Year |
Citation |
Score |
2023 |
Gajendran N, Rajasekaran S, Witt SN. Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility. Scientific Reports. 13: 9243. PMID 37286800 DOI: 10.1038/s41598-023-36451-3 |
0.37 |
|
2022 |
Rajasekaran S, Patel D, Witt SN. α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo. Biochemical and Biophysical Research Communications. 603: 7-12. PMID 35263697 DOI: 10.1016/j.bbrc.2022.01.101 |
0.323 |
|
2021 |
Rajasekaran S, Witt SN. Trojan horses and tunneling nanotubes enable α-synuclein pathology to spread in Parkinson disease. Plos Biology. 19: e3001331. PMID 34284485 DOI: 10.1371/journal.pbio.3001331 |
0.356 |
|
2021 |
Shekoohi S, Rajasekaran S, Patel D, Yang S, Liu W, Huang S, Yu X, Witt SN. Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth. Scientific Reports. 11: 5267. PMID 33664298 DOI: 10.1038/s41598-021-84443-y |
0.323 |
|
2018 |
Patel D, Witt SN. Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting. Journal of Experimental Neuroscience. 12: 1179069518796215. PMID 30158827 DOI: 10.1177/1179069518796215 |
0.324 |
|
2016 |
Wang S, Zhang S, Xu C, Barron A, Galiano F, Patel D, Lee YJ, Caldwell GA, Caldwell KA, Witt SN. Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease. Plos One. 11: e0164465. PMID 27736935 DOI: 10.1371/Journal.Pone.0164465 |
0.349 |
|
2014 |
Witt SN. Lipid disequilibrium in biological membranes, a possible pathway to neurodegeneration. Communicative & Integrative Biology. 7: e993266. PMID 26480301 DOI: 10.4161/19420889.2014.993266 |
0.366 |
|
2014 |
Wang S, Witt SN. The Parkinson's Disease-Associated Protein α-Synuclein Disrupts Stress Signaling - A Possible Implication for Methamphetamine Use? Microbial Cell. 1: 131-132. PMID 25343141 |
0.475 |
|
2014 |
Wang S, Zhang S, Liou LC, Ren Q, Zhang Z, Caldwell GA, Caldwell KA, Witt SN. Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 111: E3976-85. PMID 25201965 DOI: 10.1073/Pnas.1411694111 |
0.409 |
|
2013 |
Witt SN. Molecular chaperones, α-synuclein, and neurodegeneration. Molecular Neurobiology. 47: 552-60. PMID 22923346 DOI: 10.1007/s12035-012-8325-2 |
0.396 |
|
2012 |
Wang S, Xu B, Liou LC, Ren Q, Huang S, Luo Y, Zhang Z, Witt SN. α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2. Proceedings of the National Academy of Sciences of the United States of America. 109: 16119-24. PMID 22988096 DOI: 10.1073/Pnas.1206286109 |
0.399 |
|
2011 |
Lee YJ, Burlet E, Wang S, Xu B, Huang S, Galiano FJ, Witt SN. Triclabendazole protects yeast and mammalian cells from oxidative stress: identification of a potential neuroprotective compound. Biochemical and Biophysical Research Communications. 414: 205-8. PMID 21946065 DOI: 10.1016/j.bbrc.2011.09.057 |
0.399 |
|
2011 |
Liu X, Lee YJ, Liou LC, Ren Q, Zhang Z, Wang S, Witt SN. Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast. Human Molecular Genetics. 20: 3401-14. PMID 21642386 DOI: 10.1093/Hmg/Ddr246 |
0.41 |
|
2011 |
Lee YJ, Burlet E, Galiano F, Circu ML, Aw TY, Williams BJ, Witt SN. Phosphate and succinate use different mechanisms to inhibit sugar-induced cell death in yeast: insight into the Crabtree effect. The Journal of Biological Chemistry. 286: 20267-74. PMID 21515692 DOI: 10.1074/jbc.M110.209379 |
0.358 |
|
2011 |
Lee YJ, Wang S, Slone SR, Yacoubian TA, Witt SN. Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. Plos One. 6: e15946. PMID 21264320 DOI: 10.1371/Journal.Pone.0015946 |
0.335 |
|
2010 |
Witt SN. Hsp70 molecular chaperones and Parkinson's disease. Biopolymers. 93: 218-28. PMID 19768775 DOI: 10.1002/bip.21302 |
0.313 |
|
2006 |
Witt SN, Flower TR. alpha-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease. Fems Yeast Research. 6: 1107-16. PMID 17156009 DOI: 10.1111/j.1567-1364.2006.00135.x |
0.388 |
|
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