Jeffrey M. Wells, Ph.D. - Publications

Affiliations: 
2004 State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Medical Biophysics, Oncology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Honoré C, Rescan C, Hald J, McGrath PS, Petersen MB, Hansson M, Klein T, Østergaard S, Wells JM, Madsen OD. Revisiting the immunocytochemical detection of Neurogenin 3 expression in mouse and man. Diabetes, Obesity & Metabolism. 18: 10-22. PMID 27615127 DOI: 10.1111/dom.12718  0.4
2016 McCauley HA, Wells JM. Sweet Relief: Reprogramming Gastric Endocrine Cells to Make Insulin. Cell Stem Cell. 18: 295-7. PMID 26942844 DOI: 10.1016/j.stem.2016.02.009  0.4
2016 Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem Cell Reports. 6: 44-54. PMID 26771352 DOI: 10.1016/j.stemcr.2015.12.001  0.4
2015 Dye BR, Hill DR, Ferguson MA, Tsai YH, Nagy MS, Dyal R, Wells JM, Mayhew CN, Nattiv R, Klein OD, White ES, Deutsch GH, Spence JR. In vitro generation of human pluripotent stem cell derived lung organoids. Elife. 4. PMID 25803487 DOI: 10.7554/eLife.05098  0.4
2015 Sinagoga KL, Wells JM. Generating human intestinal tissues from pluripotent stem cells to study development and disease. The Embo Journal. 34: 1149-63. PMID 25792515 DOI: 10.15252/embj.201490686  0.4
2015 McGrath PS, Watson CL, Ingram C, Helmrath MA, Wells JM. The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas. Diabetes. 64: 2497-505. PMID 25650326 DOI: 10.2337/db14-1412  0.4
2015 Wells JM. Developmental biology. Regional identity of gut stem cells--one gene to rule them all. Nature Reviews. Gastroenterology & Hepatology. 12: 125-6. PMID 25645971 DOI: 10.1038/nrgastro.2015.22  0.4
2015 Ji H, Zhang X, Oh S, Mayhew CN, Ulm A, Somineni HK, Ericksen M, Wells JM, Khurana Hershey GK. Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells. The Journal of Allergy and Clinical Immunology. 135: 236-44. PMID 25441642 DOI: 10.1016/J.Jaci.2014.08.038  0.4
2014 McCracken KW, Catá EM, Crawford CM, Sinagoga KL, Schumacher M, Rockich BE, Tsai YH, Mayhew CN, Spence JR, Zavros Y, Wells JM. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature. 516: 400-4. PMID 25363776 DOI: 10.1038/Nature13863  0.4
2014 Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, et al. An in vivo model of human small intestine using pluripotent stem cells. Nature Medicine. 20: 1310-4. PMID 25326803 DOI: 10.1038/Nm.3737  0.4
2014 Jonatan D, Spence JR, Method AM, Kofron M, Sinagoga K, Haataja L, Arvan P, Deutsch GH, Wells JM. Sox17 regulates insulin secretion in the normal and pathologic mouse β cell. Plos One. 9: e104675. PMID 25144761 DOI: 10.1371/journal.pone.0104675  0.4
2014 Chlon TM, Hoskins EE, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells. Journal of Virology. 88: 11315-26. PMID 25031356 DOI: 10.1128/JVI.01533-14  0.4
2014 Schiesser JV, Wells JM. Generation of β cells from human pluripotent stem cells: are we there yet? Annals of the New York Academy of Sciences. 1311: 124-37. PMID 24611778 DOI: 10.1111/nyas.12369  0.4
2014 Runck LA, Method A, Bischoff A, Levitt M, Peña A, Collins MH, Gupta A, Shanmukhappa S, Wells JM, Guasch G. Defining the molecular pathologies in cloaca malformation: similarities between mouse and human. Disease Models & Mechanisms. 7: 483-93. PMID 24524909 DOI: 10.1242/Dmm.014530  0.4
2014 Wells JM, Spence JR. How to make an intestine. Development (Cambridge, England). 141: 752-60. PMID 24496613 DOI: 10.1242/dev.097386  0.4
2014 Xie W, Lynch TJ, Liu X, Tyler SR, Yu S, Zhou X, Luo M, Kusner DM, Sun X, Yi Y, Zhang Y, Goodheart MJ, Parekh KR, Wells JM, Xue HH, et al. Sox2 modulates Lef-1 expression during airway submucosal gland development. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L645-60. PMID 24487391 DOI: 10.1152/Ajplung.00157.2013  0.4
2014 Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC. Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 146: 233-44.e5. PMID 23999170 DOI: 10.1053/J.Gastro.2013.08.053  0.4
2014 Method AM, Wells JM. Patterning the Embryonic Endoderm into Presumptive Organ Domains Principles of Developmental Genetics: Second Edition. 545-564. DOI: 10.1016/B978-0-12-405945-0.00030-2  0.4
2013 Brugmann SA, Wells JM. Building additional complexity to in vitro-derived intestinal tissues. Stem Cell Research & Therapy. 4: S1. PMID 24565179 DOI: 10.1186/Scrt362  0.4
2013 Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. Plos One. 8: e70397. PMID 23940571 DOI: 10.1371/Journal.Pone.0070397  0.4
2013 Yang H, Lee S, Lee S, Kim K, Yang Y, Kim JH, Adams RH, Wells JM, Morrison SJ, Koh GY, Kim I. Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice. The Journal of Clinical Investigation. 123: 418-31. PMID 23241958 DOI: 10.1172/Jci64547  0.4
2012 McCracken KW, Wells JM. Molecular pathways controlling pancreas induction. Seminars in Cell & Developmental Biology. 23: 656-62. PMID 22743233 DOI: 10.1016/j.semcdb.2012.06.009  0.4
2012 Du A, McCracken KW, Walp ER, Terry NA, Klein TJ, Han A, Wells JM, May CL. Arx is required for normal enteroendocrine cell development in mice and humans. Developmental Biology. 365: 175-88. PMID 22387004 DOI: 10.1016/J.Ydbio.2012.02.024  0.4
2011 McCracken KW, Howell JC, Wells JM, Spence JR. Generating human intestinal tissue from pluripotent stem cells in vitro. Nature Protocols. 6: 1920-8. PMID 22082986 DOI: 10.1038/nprot.2011.410  0.4
2011 Howell JC, Wells JM. Generating intestinal tissue from stem cells: Potential for research and therapy Regenerative Medicine. 6: 743-755. PMID 22050526 DOI: 10.2217/rme.11.90  0.4
2011 Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, et al. The human DEK oncogene regulates DNA damage response signaling and repair. Nucleic Acids Research. 39: 7465-76. PMID 21653549 DOI: 10.1093/Nar/Gkr454  0.4
2011 Murtaugh LC, Wells JM. Understanding endoderm development: more than just a series of tubes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 461-2. PMID 21337458 DOI: 10.1002/dvdy.22587  0.4
2011 Spence JR, Mayhew CN, Rankin SA, Kuhar MF, Vallance JE, Tolle K, Hoskins EE, Kalinichenko VV, Wells SI, Zorn AM, Shroyer NF, Wells JM. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature. 470: 105-9. PMID 21151107 DOI: 10.1038/nature09691  0.4
2010 Lin SC, Wani MA, Whitsett JA, Wells JM. Klf5 regulates lineage formation in the pre-implantation mouse embryo. Development (Cambridge, England). 137: 3953-63. PMID 20980403 DOI: 10.1242/dev.054775  0.4
2010 Gimelli S, Caridi G, Beri S, McCracken K, Bocciardi R, Zordan P, Dagnino M, Fiorio P, Murer L, Benetti E, Zuffardi O, Giorda R, Wells JM, Gimelli G, Ghiggeri GM. Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract Human Mutation. 31: 1352-1359. PMID 20960469 DOI: 10.1002/humu.21378  0.4
2010 Liu X, Luo M, Xie W, Wells JM, Goodheart MJ, Engelhardt JF. Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L694-710. PMID 20802155 DOI: 10.1152/Ajplung.00140.2010  0.4
2010 Carpenter AC, Rao S, Wells JM, Campbell K, Lang RA. Generation of mice with a conditional null allele for Wntless. Genesis (New York, N.Y. : 2000). 48: 554-8. PMID 20614471 DOI: 10.1002/Dvg.20651  0.4
2010 Mayhew CN, Wells JM. Converting human pluripotent stem cells into β-cells: Recent advances and future challenges Current Opinion in Organ Transplantation. 15: 54-60. PMID 19855279 DOI: 10.1097/MOT.0b013e3283337e1c  0.4
2009 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM. Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Developmental Cell. 17: 62-74. PMID 19619492 DOI: 10.1016/J.Devcel.2009.05.012  0.4
2009 Zorn AM, Wells JM. Vertebrate endoderm development and organ formation Annual Review of Cell and Developmental Biology. 25: 221-251. PMID 19575677 DOI: 10.1146/annurev.cellbio.042308.113344  0.4
2009 Lange AW, Keiser AR, Wells JM, Zorn AM, Whitsett JA. Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. Plos One. 4: e5711. PMID 19479035 DOI: 10.1371/journal.pone.0005711  0.4
2007 Spence JR, Wells JM. Translational embryology: using embryonic principles to generate pancreatic endocrine cells from embryonic stem cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 3218-27. PMID 17973329 DOI: 10.1002/dvdy.21366  0.4
2003 Wells J, Sen A, Hui SW. Localized delivery to CT-26 tumors in mice using thermosensitive liposomes. International Journal of Pharmaceutics. 261: 105-14. PMID 12878399 DOI: 10.1016/S0378-5173(03)00290-4  0.4
2000 Wells JM, Li LH, Sen A, Jahreis GP, Hui SW. Electroporation-enhanced gene delivery in mammary tumors. Gene Therapy. 7: 541-7. PMID 10819568 DOI: 10.1038/Sj.Gt.3301141  0.4
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