| Year |
Citation |
Score |
| 2024 |
Ohya Y, Ogiso Y, Matsuda M, Sakae H, Nishida K, Miki Y, Fox TE, Kester M, Sakamoto W, Nabe T, Kitatani K. Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells. Cells. 13. PMID 38474369 DOI: 10.3390/cells13050405 |
0.551 |
|
| 2024 |
Paudel BB, Tan SF, Fox TE, Ung J, Golla U, Shaw JJP, Dunton W, Lee IS, Fares W, Patel S, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot MC, et al. Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes. Blood Advances. PMID 38170742 DOI: 10.1182/bloodadvances.2023010535 |
0.419 |
|
| 2023 |
Ung J, Tan SF, Fox TE, Shaw JJP, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers. 15. PMID 38136410 DOI: 10.3390/cancers15245866 |
0.316 |
|
| 2023 |
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Biorxiv : the Preprint Server For Biology. PMID 37961314 DOI: 10.1101/2023.10.21.563437 |
0.314 |
|
| 2023 |
Feng TY, Melchor SJ, Zhao XY, Ghumman H, Kester M, Fox TE, Ewald SE. Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in infection-induced cachexia. Heliyon. 9: e17411. PMID 37456044 DOI: 10.1016/j.heliyon.2023.e17411 |
0.482 |
|
| 2023 |
Thim EA, Fox T, Deering T, Vass LR, Sheybani ND, Kester M, Price RJ. Solid tumor treatment via augmentation of bioactive C6 ceramide levels with thermally ablative focused ultrasound. Drug Delivery and Translational Research. PMID 37335416 DOI: 10.1007/s13346-023-01377-w |
0.497 |
|
| 2023 |
Paudel BB, Tan SF, Fox TE, Ung J, Shaw J, Dunton W, Lee I, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, et al. Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes. Biorxiv : the Preprint Server For Biology. PMID 37131653 DOI: 10.1101/2023.04.13.536805 |
0.453 |
|
| 2023 |
Thim EA, Fox T, Deering T, Vass LR, Sheybani ND, Kester M, Price RJ. Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound. Biorxiv : the Preprint Server For Biology. PMID 36993445 DOI: 10.1101/2023.03.23.532394 |
0.496 |
|
| 2023 |
Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, et al. Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia. Cancers. 15. PMID 36980769 DOI: 10.3390/cancers15061883 |
0.53 |
|
| 2023 |
Sakae H, Ogiso Y, Matsuda M, Shimora H, Deering T, Fox TE, Kester M, Nabe T, Kitatani K. Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma. Cells. 12. PMID 36831258 DOI: 10.3390/cells12040591 |
0.498 |
|
| 2022 |
Salotto KE, Olson WC, Pollack KE, Illendula A, Michel E, Henriques S, Fox T, Walker S, Dunlap-Brown M, Slingluff CL, Kester M, Snyder HW. A nano-enhanced vaccine for metastatic melanoma immunotherapy. Cancer Drug Resistance (Alhambra, Calif.). 5: 829-845. PMID 36176766 DOI: 10.20517/cdr.2021.132 |
0.483 |
|
| 2022 |
Khokhlatchev AV, Sharma A, Deering TG, Shaw JJP, Costa-Pinheiro P, Golla U, Annageldiyev C, Cabot MC, Conaway MR, Tan SF, Ung J, Feith DJ, Loughran TP, Claxton DF, Fox TE, et al. Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22514. PMID 36106439 DOI: 10.1096/fj.202200765R |
0.576 |
|
| 2022 |
LeBlanc FR, Hasanali ZS, Stuart A, Shimko S, Sharma K, Leshchenko VV, Parekh S, Fu H, Zhang Y, Martin MM, Kester M, Fox T, Liao J, Loughran TP, Evans J, et al. Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma. Oncotarget. 13: 986-1002. PMID 36093297 DOI: 10.18632/oncotarget.28258 |
0.499 |
|
| 2022 |
Ung J, Tan SF, Fox TE, Shaw JJP, Vass LR, Costa-Pinheiro P, Garrett-Bakelman FE, Keng MK, Sharma A, Claxton DF, Levine RL, Tallman MS, Cabot MC, Kester M, Feith DJ, et al. Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia. Blood Reviews. 100950. PMID 35487785 DOI: 10.1016/j.blre.2022.100950 |
0.52 |
|
| 2022 |
DiPasquale M, Deering TG, Desai D, Sharma AK, Amin S, Fox TE, Kester M, Katsaras J, Marquardt D, Heberle FA. Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation. Chemistry and Physics of Lipids. 105205. PMID 35483419 DOI: 10.1016/j.chemphyslip.2022.105205 |
0.487 |
|
| 2022 |
Qi X, Wu F, Kim SH, Kaifi JT, Kimchi ET, Snyder H, Illendula A, Fox T, Kester M, Staveley-O'Carroll KF, Li G. Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22250. PMID 35294071 DOI: 10.1096/fj.202101707R |
0.487 |
|
| 2022 |
Fisher-Wellman KH, Hagen JT, Kassai M, Kao LP, Nelson MAM, McLaughlin KL, Coalson HS, Fox TE, Tan SF, Feith DJ, Kester M, Loughran TP, Claxton DF, Cabot MC. Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22094. PMID 34888943 DOI: 10.1096/fj.202101194RRR |
0.525 |
|
| 2020 |
Costa-Pinheiro P, Heher A, Raymond MH, Jividen K, Shaw JJ, Paschal BM, Walker SJ, Fox TE, Kester M. Role of SPTSSB-Regulated de Novo Sphingolipid Synthesis in Prostate Cancer Depends on Androgen Receptor Signaling. Iscience. 23: 101855. PMID 33313495 DOI: 10.1016/j.isci.2020.101855 |
0.516 |
|
| 2020 |
Shaw JJ, Boyer TL, Venner E, Beck PJ, Slamowitz T, Caste T, Hickman A, Raymond MH, Costa-Pinheiro P, Jameson MJ, Fox TE, Kester M. Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma. Molecular Cancer Therapeutics. PMID 33087509 DOI: 10.1158/1535-7163.MCT-20-0182 |
0.532 |
|
| 2020 |
Patterson L, Allen J, Posey I, Shaw JJP, Costa-Pinheiro P, Walker SJ, Gademsey A, Wu X, Wu S, Zachos NC, Fox TE, Sears CL, Kester M. Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin-induced colon epithelial cell signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33047400 DOI: 10.1096/fj.202001669R |
0.505 |
|
| 2020 |
Keppley LJW, Walker SJ, Gademsey AN, Smith JP, Keller SR, Kester M, Fox TE. Nervonic acid limits weight gain in a mouse model of diet-induced obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32959931 DOI: 10.1096/Fj.202000525R |
0.432 |
|
| 2020 |
Zanieri F, Levi A, Montefusco D, Longato L, De Chiara F, Frenguelli L, Omenetti S, Andreola F, Luong TV, Massey V, Caballeria J, Fondevila C, Shanmugavelandy SS, Fox T, Mazza G, et al. Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH. Cells. 9. PMID 32429478 DOI: 10.3390/Cells9051237 |
0.592 |
|
| 2020 |
Drews K, Calgi MP, Harrison WC, Drews CM, Costa-Pinheiro P, Shaw JJP, Jobe KA, Han JD, Fox TE, White JM, Kester M. Glucosylceramide synthase maintains influenza virus entry and infection. Plos One. 15: e0228735. PMID 32032363 DOI: 10.1371/Journal.Pone.0228735 |
0.449 |
|
| 2020 |
Costa-Pinheiro P, Heher A, Raymond M, Jividen K, Fox T, Kester M. Abstract 2079: Ceramide nanoliposomes a novel therapeutic option for androgen receptor negative prostate cancer Epidemiology. DOI: 10.1158/1538-7445.Am2020-2079 |
0.504 |
|
| 2019 |
Pearson JM, Tan SF, Sharma A, Annageldiyev C, Fox TE, Abad JL, Fabrias G, Desai D, Amin S, Wang HG, Cabot MC, Claxton DF, Kester M, Feith DJ, Loughran TP. Ceramide analog SACLAC modulates sphingolipid levels and Mcl-1 splicing to induce apoptosis in acute myeloid leukemia. Molecular Cancer Research : McR. PMID 31744877 DOI: 10.1158/1541-7786.Mcr-19-0619 |
0.563 |
|
| 2019 |
Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, et al. Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia. Blood Advances. 3: 2598-2603. PMID 31488436 DOI: 10.1182/Bloodadvances.2018021295 |
0.502 |
|
| 2019 |
Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, et al. Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells. Journal of Lipid Research. PMID 31363040 DOI: 10.1194/Jlr.Ra119000251 |
0.577 |
|
| 2019 |
Moore JH, Varhue WB, Su YH, Linton SS, Farmehini V, Fox TE, Matters GL, Kester M, Swami NS. Conductance-based biophysical distinction and microfluidic enrichment of nano-vesicles derived from pancreatic tumor cells of varying invasiveness. Analytical Chemistry. PMID 31333013 DOI: 10.1021/Acs.Analchem.8B05745 |
0.503 |
|
| 2019 |
Tan SF, Dunton W, Liu X, Fox TE, Morad SAF, Desai D, Doi K, Conaway MR, Amin S, Claxton DF, Wang HG, Kester M, Cabot MC, Feith DJ, Loughran TP. Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-kB-dependent P-glycoprotein upregulation. Journal of Lipid Research. PMID 30962310 DOI: 10.1194/Jlr.M091876 |
0.481 |
|
| 2019 |
Drews K, Calgi MP, Harrison WC, Drews CM, Costa-Pinheiro P, Shaw JJP, Jobe KA, Nelson EA, Han JD, Fox T, White JM, Kester M. Glucosylceramidase Maintains Influenza Infection By Regulating Endocytosis. Journal of Virology. PMID 30918081 DOI: 10.1128/Jvi.00017-19 |
0.527 |
|
| 2018 |
Linton SS, Abraham T, Liao J, Clawson GA, Butler PJ, Fox T, Kester M, Matters GL. Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages. Plos One. 13: e0206759. PMID 30383833 DOI: 10.1371/Journal.Pone.0206759 |
0.555 |
|
| 2018 |
Li G, Liu D, Kimchi ET, Kaifi JT, Qi X, Manjunath Y, Liu X, Deering T, Fox T, Rockey DC, Schell TD, Kester M, Avella DM, Staveley-O'Carroll KF. Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice. Gastroenterology. PMID 29408569 DOI: 10.1053/J.Gastro.2017.10.050 |
0.565 |
|
| 2017 |
Doshi UA, Shaw J, Fox TE, Claxton DF, Loughran TP, Kester M. STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia. Signal Transduction and Targeted Therapy. 2: 17051. PMID 29263930 DOI: 10.1038/Sigtrans.2017.51 |
0.587 |
|
| 2017 |
Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Usui T, Minato J, Egiz M, Shigeta S, Fox T, Deering T, Kester M, Yaegashi N. Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer. Molecular Cancer Therapeutics. PMID 29079707 DOI: 10.1158/1535-7163.Mct-17-0173 |
0.62 |
|
| 2017 |
Shin M, Snyder HW, Donvito G, Schurman LD, Fox TE, Lichtman AH, Kester M, Hsu KL. Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. Molecular Pharmaceutics. PMID 28901776 DOI: 10.1021/Acs.Molpharmaceut.7B00657 |
0.487 |
|
| 2017 |
Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, et al. SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models. Cancer Translational Medicine. 3: 109-121. PMID 28890935 DOI: 10.4103/Ctm.Ctm_7_17 |
0.484 |
|
| 2017 |
Loc WS, Linton SS, Wilczynski ZR, Matters GL, McGovern CO, Abraham T, Fox T, Gigliotti CM, Tang X, Tabakovic A, Martin JA, Clawson GA, Smith JP, Butler PJ, Kester M, et al. Effective Encapsulation and Biological Activity of Phosphorylated Chemotherapeutics in Calcium Phosphosilicate Nanoparticles for the Treatment of Pancreatic Cancer. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28673852 DOI: 10.1016/J.Nano.2017.06.017 |
0.57 |
|
| 2017 |
Vijayan M, Xia C, Song YE, Ngo H, Studstill CJ, Drews K, Fox TE, Johnson MC, Hiscott J, Kester M, Alexander S, Hahm B. Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28600291 DOI: 10.4049/Jimmunol.1601959 |
0.467 |
|
| 2016 |
Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, et al. Acid ceramidase is upregulated in AML and represents a novel therapeutic target. Oncotarget. PMID 27825124 DOI: 10.18632/Oncotarget.13079 |
0.568 |
|
| 2016 |
Young MM, Takahashi Y, Fox TE, Yun JK, Kester M, Wang HG. Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking. Cell Reports. 17: 1532-1545. PMID 27806293 DOI: 10.1016/J.Celrep.2016.10.019 |
0.478 |
|
| 2016 |
Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC. Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. Journal of Lipid Research. PMID 27140664 DOI: 10.1194/Jlr.M067389 |
0.579 |
|
| 2016 |
Rivera IG, Ordoñez M, Presa N, Gangoiti P, Gomez-Larrauri A, Trueba M, Fox T, Kester M, Gomez-Muñoz A. Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells. Biochemical Pharmacology. 102: 107-19. PMID 26707801 DOI: 10.1016/J.Bcp.2015.12.009 |
0.624 |
|
| 2016 |
Rivera IG, Ordoñez M, Presa N, Gangoiti P, Gomez-Larrauri A, Trueba M, Fox T, Kester M, Gomez-Muñoz A. Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells Biochemical Pharmacology. 102: 107-119. DOI: 10.1016/j.bcp.2015.12.009 |
0.54 |
|
| 2015 |
LeBlanc FR, Liu X, Hengst J, Fox T, Calvert V, Petricoin EF, Yun J, Feith DJ, Loughran TP. Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia. Cancer Biology & Therapy. 0. PMID 26252351 DOI: 10.1080/15384047.2015.1078949 |
0.444 |
|
| 2015 |
Kester M, Bassler J, Fox TE, Carter CJ, Davidson JA, Parette MR. Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic. Biological Chemistry. 396: 737-47. PMID 25838296 DOI: 10.1515/Hsz-2015-0129 |
0.464 |
|
| 2015 |
Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP, Barth BM, Fox TE, Cabot MC. Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia-Impact on enzyme activity and response to cytotoxics. Biochimica Et Biophysica Acta. 1851: 919-28. PMID 25769964 DOI: 10.1016/J.Bbalip.2015.03.001 |
0.595 |
|
| 2015 |
Haakenson JK, Khokhlatchev AV, Choi YJ, Linton SS, Zhang P, Zaki PM, Fu C, Cooper TK, Manni A, Zhu J, Fox TE, Dong C, Kester M. Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells. The Journal of Biological Chemistry. 290: 8632-43. PMID 25681441 DOI: 10.1074/Jbc.M114.609677 |
0.53 |
|
| 2015 |
Dick TE, Hengst JA, Fox TE, Colledge AL, Kale VP, Sung SS, Sharma A, Amin S, Loughran TP, Kester M, Wang HG, Yun JK. The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines. The Journal of Pharmacology and Experimental Therapeutics. 352: 494-508. PMID 25563902 DOI: 10.1124/Jpet.114.219659 |
0.563 |
|
| 2015 |
Tan S, Liu X, Broeg K, Fox TE, Feith DJ, Loughran TP. Acid Ceramidase Inhibition Impairs Tumor Progression in a Rat Model of LGL Leukemia Blood. 126: 1246-1246. DOI: 10.1182/Blood.V126.23.1246.1246 |
0.352 |
|
| 2013 |
Jiang Y, DiVittore NA, Young MM, Jia Z, Xie K, Ritty TM, Kester M, Fox TE. Altered sphingolipid metabolism in patients with metastatic pancreatic cancer. Biomolecules. 3: 435-48. PMID 24970174 DOI: 10.3390/biom3030435 |
0.5 |
|
| 2013 |
Ryland LK, Doshi UA, Shanmugavelandy SS, Fox TE, Aliaga C, Broeg K, Baab KT, Young M, Khan O, Haakenson JK, Jarbadan NR, Liao J, Wang HG, Feith DJ, Loughran TP, et al. C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia. Plos One. 8: e84648. PMID 24367685 DOI: 10.1371/Journal.Pone.0084648 |
0.804 |
|
| 2013 |
Morad SA, Levin JC, Tan SF, Fox TE, Feith DJ, Cabot MC. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells. Biochimica Et Biophysica Acta. 1831: 1657-64. PMID 23939396 DOI: 10.1016/J.Bbalip.2013.07.016 |
0.31 |
|
| 2013 |
Hankins JL, Ward KE, Linton SS, Barth BM, Stahelin RV, Fox TE, Kester M. Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex. The Journal of Biological Chemistry. 288: 19726-38. PMID 23696646 DOI: 10.1074/Jbc.M113.481622 |
0.773 |
|
| 2013 |
Barth BM, Shanmugavelandy SS, Kaiser JM, McGovern C, Altınoğlu Eİ, Haakenson JK, Hengst JA, Gilius EL, Knupp SA, Fox TE, Smith JP, Ritty TM, Adair JH, Kester M. PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate. Acs Nano. 7: 2132-44. PMID 23373542 DOI: 10.1021/Nn304862B |
0.576 |
|
| 2013 |
Watters RJ, Fox TE, Tan SF, Shanmugavelandy S, Choby JE, Broeg K, Liao J, Kester M, Cabot MC, Loughran TP, Liu X. Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia. Leukemia & Lymphoma. 54: 1288-96. PMID 23181473 DOI: 10.3109/10428194.2012.752485 |
0.589 |
|
| 2013 |
Kaiser JM, Imai H, Haakenson JK, Brucklacher RM, Fox TE, Shanmugavelandy SS, Unrath KA, Pedersen MM, Dai P, Freeman WM, Bronson SK, Gardner TW, Kester M. Nanoliposomal minocycline for ocular drug delivery. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 130-40. PMID 22465498 DOI: 10.1016/J.Nano.2012.03.004 |
0.451 |
|
| 2012 |
Fox TE, Young MM, Pedersen MM, Han X, Gardner TW, Kester M. Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death. Investigative Ophthalmology & Visual Science. 53: 7257-67. PMID 22952117 DOI: 10.1167/Iovs.11-7626 |
0.486 |
|
| 2012 |
LeBlanc F, Liu X, Fox T, Shah M, Rogers A, Ryland L, Kester M, Yun J, Loughran TP. Targeting Sphingosine Kinase 1 in NK-LGL Leukemia Blood. 120: 1313-1313. DOI: 10.1182/Blood.V120.21.1313.1313 |
0.785 |
|
| 2011 |
Hankins JL, Fox TE, Barth BM, Unrath KA, Kester M. Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression. The Journal of Biological Chemistry. 286: 44357-66. PMID 22065582 DOI: 10.1074/Jbc.M111.264010 |
0.765 |
|
| 2011 |
Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer. Cancer Biology & Therapy. 12: 574-85. PMID 21795855 DOI: 10.4161/Cbt.12.7.15971 |
0.804 |
|
| 2011 |
Liao A, Broeg K, Fox T, Tan SF, Watters R, Shah MV, Zhang LQ, Li Y, Ryland L, Yang J, Aliaga C, Dewey A, Rogers A, Loughran K, Hirsch L, et al. Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia. Blood. 118: 2793-800. PMID 21768294 DOI: 10.1182/Blood-2011-01-331447 |
0.784 |
|
| 2011 |
Heakal Y, Woll MP, Fox T, Seaton K, Levenson R, Kester M. Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains. Cancer Biology & Therapy. 12: 427-35. PMID 21725197 DOI: 10.4161/Cbt.12.5.15984 |
0.79 |
|
| 2011 |
O'Neill SM, Yun JK, Fox TE, Kester M. Transcriptional regulation of the human neutral ceramidase gene. Archives of Biochemistry and Biophysics. 511: 21-30. PMID 21531200 DOI: 10.1016/J.Abb.2011.04.012 |
0.45 |
|
| 2011 |
O'Neill SM, Houck KL, Yun JK, Fox TE, Kester M. AP-1 binding transcriptionally regulates human neutral ceramidase. Archives of Biochemistry and Biophysics. 511: 31-9. PMID 21530485 DOI: 10.1016/J.Abb.2011.04.009 |
0.778 |
|
| 2011 |
Ryland LK, Fox TE, Liu X, Loughran TP, Kester M. Dysregulation of sphingolipid metabolism in cancer. Cancer Biology & Therapy. 11: 138-49. PMID 21209555 DOI: 10.4161/Cbt.11.2.14624 |
0.76 |
|
| 2011 |
Fox TE, Young MM, Pedersen MM, Giambuzzi-Tussey S, Kester M, Gardner TW. Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains. American Journal of Physiology. Endocrinology and Metabolism. 300: E600-9. PMID 21205932 DOI: 10.1152/Ajpendo.00641.2010 |
0.484 |
|
| 2011 |
Takahashi Y, Meyerkord CL, Hori T, Runkle K, Fox TE, Kester M, Loughran TP, Wang HG. Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. Autophagy. 7: 61-73. PMID 21068542 DOI: 10.4161/Auto.7.1.14015 |
0.494 |
|
| 2011 |
Fox TE, Bewley MC, Unrath KA, Pedersen MM, Anderson RE, Jung DY, Jefferson LS, Kim JK, Bronson SK, Flanagan JM, Kester M. Circulating sphingolipid biomarkers in models of type 1 diabetes. Journal of Lipid Research. 52: 509-17. PMID 21068007 DOI: 10.1194/Jlr.M010595 |
0.442 |
|
| 2010 |
Barth BM, Gustafson SJ, Young MM, Fox TE, Shanmugavelandy SS, Kaiser JM, Cabot MC, Kester M, Kuhn TB. Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance. Cancer Biology & Therapy. 10: 1126-36. PMID 20935456 DOI: 10.4161/Cbt.10.11.13438 |
0.543 |
|
| 2010 |
Fox TE, Kester M. Therapeutic strategies for diabetes and complications: a role for sphingolipids? Advances in Experimental Medicine and Biology. 688: 206-16. PMID 20919656 DOI: 10.1007/978-1-4419-6741-1_14 |
0.445 |
|
| 2010 |
Winter JN, Fox TE, Kester M, Jefferson LS, Kimball SR. Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. American Journal of Physiology. Cell Physiology. 299: C335-44. PMID 20427710 DOI: 10.1152/Ajpcell.00039.2010 |
0.512 |
|
| 2010 |
Ganapathi SB, Fox TE, Kester M, Elmslie KS. Ceramide modulates HERG potassium channel gating by translocation into lipid rafts. American Journal of Physiology. Cell Physiology. 299: C74-86. PMID 20375276 DOI: 10.1152/Ajpcell.00462.2009 |
0.769 |
|
| 2010 |
Wijesinghe DS, Allegood JC, Gentile LB, Fox TE, Kester M, Chalfant CE. Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels. Journal of Lipid Research. 51: 641-51. PMID 19654423 DOI: 10.1194/Jlr.D000430 |
0.467 |
|
| 2009 |
Salli U, Fox TE, Carkaci-Salli N, Sharma A, Robertson GP, Kester M, Vrana KE. Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide. Stem Cells and Development. 18: 55-65. PMID 18393629 DOI: 10.1089/Scd.2007.0271 |
0.525 |
|
| 2008 |
O'Neill SM, Olympia DK, Fox TE, Brown JT, Stover TC, Houck KL, Wilson R, Waybill P, Kozak M, Levison SW, Weber N, Karavodin LM, Kester M. C(6)-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries. Vascular Disease Prevention. 5: 200-210. PMID 19946459 DOI: 10.2174/156727008785133809 |
0.749 |
|
| 2008 |
Kester M, Heakal Y, Fox T, Sharma A, Robertson GP, Morgan TT, Altinoğlu EI, Tabaković A, Parette MR, Rouse SM, Ruiz-Velasco V, Adair JH. Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells. Nano Letters. 8: 4116-21. PMID 19367878 DOI: 10.1021/Nl802098G |
0.759 |
|
| 2008 |
Pearlman E, Johnson A, Adhikary G, Sun Y, Chinnery HR, Fox T, Kester M, McMenamin PG. Toll-like receptors at the ocular surface. The Ocular Surface. 6: 108-16. PMID 18781257 DOI: 10.1016/S1542-0124(12)70279-3 |
0.521 |
|
| 2008 |
Houck KL, Fox TE, Sandirasegarane L, Kester M. Ether-linked diglycerides inhibit vascular smooth muscle cell growth via decreased MAPK and PI3K/Akt signaling. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1657-68. PMID 18723771 DOI: 10.1152/Ajpheart.00141.2008 |
0.793 |
|
| 2008 |
Sun Y, Fox T, Adhikary G, Kester M, Pearlman E. Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide. Journal of Leukocyte Biology. 83: 1512-21. PMID 18372342 DOI: 10.1189/Jlb.0108076 |
0.596 |
|
| 2007 |
Fox TE, Houck KL, O'Neill SM, Nagarajan M, Stover TC, Pomianowski PT, Unal O, Yun JK, Naides SJ, Kester M. Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains. The Journal of Biological Chemistry. 282: 12450-7. PMID 17308302 DOI: 10.1074/Jbc.M700082200 |
0.762 |
|
| 2006 |
Fox TE, Han X, Kelly S, Merrill AH, Martin RE, Anderson RE, Gardner TW, Kester M. Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy. Diabetes. 55: 3573-80. PMID 17130506 DOI: 10.2337/Db06-0539 |
0.469 |
|
| Show low-probability matches. |