Patricia Wadsworth - Publications

Affiliations: 
Molecular & Cellular Biology University of Massachusetts, Amherst, Amherst, MA 
Area:
General Biology, Cell Biology, General Biophysics

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Verma V, Wadsworth P, Maresca TJ. Human dynein-dynactin is a fast processive motor in living cells. Biorxiv : the Preprint Server For Biology. PMID 38076961 DOI: 10.1101/2023.11.28.569102  0.37
2023 Fermino do Rosário C, Zhang Y, Stadnicki J, Ross JL, Wadsworth P. Lateral and longitudinal compaction of PRC1 overlap zones drives stabilization of interzonal microtubules. Molecular Biology of the Cell. mbcE23020049. PMID 37467037 DOI: 10.1091/mbc.E23-02-0049  0.461
2023 Fermino do Rosário C, Wadsworth P. Measurement of Microtubule Stability in Mammalian Cells. Current Protocols. 3: e793. PMID 37235484 DOI: 10.1002/cpz1.793  0.484
2022 Velle KB, Kennard AS, Trupinić M, Ivec A, Swafford AJM, Nolton E, Rice LM, Tolić IM, Fritz-Laylin LK, Wadsworth P. Naegleria's mitotic spindles are built from unique tubulins and highlight core spindle features. Current Biology : Cb. PMID 35139359 DOI: 10.1016/j.cub.2022.01.034  0.357
2021 Velle KB, Fermino do Rosário C, Wadsworth P, Fritz-Laylin LK. A OneStep Solution to Fix and Stain Cells for Correlative Live and Fixed Microscopy. Current Protocols. 1: e308. PMID 34826344 DOI: 10.1002/cpz1.308  0.34
2021 Wadsworth P. The multifunctional spindle midzone in vertebrate cells at a glance. Journal of Cell Science. 134. PMID 34042161 DOI: 10.1242/jcs.250001  0.446
2018 Mann BJ, Wadsworth P. Kinesin-5 Regulation and Function in Mitosis. Trends in Cell Biology. 29: 66-79. PMID 30220581 DOI: 10.1016/J.Tcb.2018.08.004  0.51
2018 Mann BJ, Wadsworth P. Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells Cytoskeleton. 75: 508-521. PMID 30123975 DOI: 10.1002/Cm.21486  0.563
2017 Ly T, Whigham A, Clarke R, Brenes-Murillo AJ, Estes B, Madhessian D, Lundberg E, Wadsworth P, Lamond AI. Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS. Elife. 6. PMID 29052541 DOI: 10.7554/Elife.27574  0.421
2017 Bickel KG, Mann BJ, Waitzman JS, Poor TA, Rice SE, Wadsworth P. Src family kinase phosphorylation of the motor domain of the human kinesin-5, Eg5. Cytoskeleton (Hoboken, N.J.). PMID 28646493 DOI: 10.1002/Cm.21380  0.455
2017 Ly T, Whigham A, Clarke R, Brenes-Murillo AJ, Estes B, Madhessian D, Lundberg E, Wadsworth P, Lamond AI. Author response: Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS Elife. DOI: 10.7554/Elife.27574.030  0.343
2016 Mann BJ, Balchand SK, Wadsworth P. Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics. Molecular Biology of the Cell. PMID 27852894 DOI: 10.1091/Mbc.E16-06-0476  0.511
2016 Balchand SK, Mann BJ, Wadsworth P. Using Fluorescence Microscopy to Study Mitosis. Methods in Molecular Biology (Clifton, N.J.). 1413: 3-14. PMID 27193839 DOI: 10.1007/978-1-4939-3542-0_1  0.383
2016 Reid TA, Schuster BM, Mann BJ, Balchand SK, Plooster M, McClellan M, Coombes CE, Wadsworth P, Gardner MK. Suppression of microtubule assembly kinetics by the mitotic protein TPX2. Journal of Cell Science. PMID 26869224 DOI: 10.1242/Jcs.178806  0.521
2015 Balchand SK, Mann BJ, Titus J, Ross JL, Wadsworth P. TPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule. The Journal of Biological Chemistry. 290: 17367-79. PMID 26018074 DOI: 10.1074/Jbc.M114.612903  0.491
2015 Rice S, Gifford KM, Waitzman JS, Poor T, Mann B, Wadsworth P. SRC Kinase Phospho-Regulation of the Human Mitotic Kinesin Eg5 Biophysical Journal. 108: 21a. DOI: 10.1016/J.Bpj.2014.11.140  0.382
2014 Collins E, Mann BJ, Wadsworth P. Eg5 restricts anaphase B spindle elongation in mammalian cells. Cytoskeleton (Hoboken, N.J.). 71: 136-44. PMID 24285623 DOI: 10.1002/Cm.21158  0.582
2014 Gifford KM, Waitzman JS, Poor TA, Mann B, Gonzalez MC, Wadsworth P, Rice SE. SRC Phosphorylation Regulates the Human Kinesin-5, Eg5, and Disrupts the Binding of Eg5 Inhibitors Biophysical Journal. 106: 780a. DOI: 10.1016/J.Bpj.2013.11.4274  0.403
2013 Wadsworth P, Lee WL. Microtubule motors: doin' it without dynactin. Current Biology : Cb. 23: R563-5. PMID 23845243 DOI: 10.1016/J.Cub.2013.05.026  0.483
2013 Balchand SK, Titus J, Ross J, Wadsworth P. TPX2 Dynamically Binds to Microtubules and Reduces the Velocity of the Kinesin EG5 Biophysical Journal. 104: 144a. DOI: 10.1016/J.Bpj.2012.11.818  0.486
2012 Collins ES, Balchand SK, Faraci JL, Wadsworth P, Lee WL. Cell cycle-regulated cortical dynein/dynactin promotes symmetric cell division by differential pole motion in anaphase. Molecular Biology of the Cell. 23: 3380-90. PMID 22809624 DOI: 10.1091/Mbc.E12-02-0109  0.516
2012 Gable A, Qiu M, Titus J, Balchand S, Ferenz NP, Ma N, Collins ES, Fagerstrom C, Ross JL, Yang G, Wadsworth P. Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2. Molecular Biology of the Cell. 23: 1254-66. PMID 22337772 DOI: 10.1091/Mbc.E11-09-0820  0.529
2012 Wadsworth P. Using cultured mammalian cells to study mitosis. Cold Spring Harbor Protocols. 2012: 205-12. PMID 22301654 DOI: 10.1101/Pdb.Ip067850  0.445
2011 Ma N, Titus J, Gable A, Ross JL, Wadsworth P. TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle. The Journal of Cell Biology. 195: 87-98. PMID 21969468 DOI: 10.1083/Jcb.201106149  0.531
2011 Wadsworth P, Lee WL, Murata T, Baskin TI. Variations on theme: spindle assembly in diverse cells. Protoplasma. 248: 439-46. PMID 20830494 DOI: 10.1007/S00709-010-0205-X  0.504
2010 Goodson HV, Dzurisin JS, Wadsworth P. Methods for expressing and analyzing GFP-tubulin and GFP-microtubule-associated proteins. Cold Spring Harbor Protocols. 2010: pdb.top85. PMID 20810643 DOI: 10.1101/Pdb.Top85  0.395
2010 Goodson HV, Dzurisin JS, Wadsworth P. Generation of stable cell lines expressing GFP-tubulin and photoactivatable-GFP-tubulin and characterization of clones. Cold Spring Harbor Protocols. 2010: pdb.prot5480. PMID 20810628 DOI: 10.1101/Pdb.Prot5480  0.316
2010 Tulu US, Ferenz NP, Wadsworth P. Photoactivatable green fluorescent protein-tubulin. Methods in Cell Biology. 97: 81-90. PMID 20719266 DOI: 10.1016/S0091-679X(10)97005-2  0.478
2010 Miquelard-Garnier G, Zimberlin JA, Sikora CB, Wadsworth P, Crosby A. Polymer microlenses for quantifying cell sheet mechanics. Soft Matter. 6: 398-403. PMID 20445765 DOI: 10.1039/B916385A  0.398
2010 Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P. Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux. Molecular Biology of the Cell. 21: 979-88. PMID 20110350 DOI: 10.1091/Mbc.E09-07-0601  0.5
2010 Ferenz NP, Gable A, Wadsworth P. Mitotic functions of kinesin-5. Seminars in Cell & Developmental Biology. 21: 255-9. PMID 20109572 DOI: 10.1016/J.Semcdb.2010.01.019  0.5
2010 Ferenz NP, Ma N, Lee WL, Wadsworth P. Imaging protein dynamics in live mitotic cells. Methods (San Diego, Calif.). 51: 193-6. PMID 20085816 DOI: 10.1016/J.Ymeth.2010.01.018  0.51
2009 Ferenz NP, Paul R, Fagerstrom C, Mogilner A, Wadsworth P. Dynein antagonizes eg5 by crosslinking and sliding antiparallel microtubules. Current Biology : Cb. 19: 1833-8. PMID 19836236 DOI: 10.1016/J.Cub.2009.09.025  0.477
2009 Lee WL, Wadsworth P. New spindle morphogenesis model by Dynein, Nudel, and the spindle matrix. Cell Research. 19: 529-31. PMID 19421240 DOI: 10.1038/Cr.2009.49  0.459
2009 Bezanilla M, Wadsworth P. Spindle positioning: actin mediates pushing and pulling. Current Biology : Cb. 19: R168-9. PMID 19243693 DOI: 10.1016/J.Cub.2008.12.026  0.544
2008 Zimberlin JA, Wadsworth P, Crosby AJ. Living microlens arrays. Cell Motility and the Cytoskeleton. 65: 762-7. PMID 18615631 DOI: 10.1002/Cm.20302  0.399
2008 Murthy K, Wadsworth P. Dual role for microtubules in regulating cortical contractility during cytokinesis. Journal of Cell Science. 121: 2350-9. PMID 18559890 DOI: 10.1242/Jcs.027052  0.459
2007 Wadsworth P. Studying mitosis in cultured Mammalian cells. Csh Protocols. 2007: pdb.prot4674. PMID 21357020 DOI: 10.1101/Pdb.Prot4674  0.425
2007 Ferenz NP, Wadsworth P. Prophase microtubule arrays undergo flux-like behavior in mammalian cells. Molecular Biology of the Cell. 18: 3993-4002. PMID 17671163 DOI: 10.1091/Mbc.E07-05-0420  0.557
2007 Bannigan A, Scheible WR, Lukowitz W, Fagerstrom C, Wadsworth P, Somerville C, Baskin TI. A conserved role for kinesin-5 in plant mitosis. Journal of Cell Science. 120: 2819-27. PMID 17652157 DOI: 10.1242/Jcs.009506  0.484
2007 Yang Z, Tulu US, Wadsworth P, Rieder CL. Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint. Current Biology : Cb. 17: 973-80. PMID 17509882 DOI: 10.1016/J.Cub.2007.04.056  0.448
2006 Tulu US, Fagerstrom C, Ferenz NP, Wadsworth P. Molecular requirements for kinetochore-associated microtubule formation in mammalian cells. Current Biology : Cb. 16: 536-41. PMID 16527751 DOI: 10.1016/J.Cub.2006.01.060  0.573
2005 Wadsworth P, Rusan NM, Tulu US, Fagerstrom C. Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells. Nature Methods. 2: 981-7. PMID 16299485 DOI: 10.1038/Nmeth1205-981  0.403
2005 Wadsworth P. Cytokinesis: Rho marks the spot. Current Biology : Cb. 15: R871-4. PMID 16271857 DOI: 10.1016/J.Cub.2005.10.021  0.435
2005 Salaycik KJ, Fagerstrom CJ, Murthy K, Tulu US, Wadsworth P. Quantification of microtubule nucleation, growth and dynamics in wound-edge cells. Journal of Cell Science. 118: 4113-22. PMID 16118246 DOI: 10.1242/Jcs.02531  0.566
2005 Murthy K, Wadsworth P. Myosin-II-dependent localization and dynamics of F-actin during cytokinesis. Current Biology : Cb. 15: 724-31. PMID 15854904 DOI: 10.1016/J.Cub.2005.02.055  0.442
2005 Rusan NM, Wadsworth P. Centrosome fragments and microtubules are transported asymmetrically away from division plane in anaphase. The Journal of Cell Biology. 168: 21-8. PMID 15631988 DOI: 10.1083/Jcb.200409153  0.439
2004 Wadsworth P, Khodjakov A. E pluribus unum: towards a universal mechanism for spindle assembly. Trends in Cell Biology. 14: 413-9. PMID 15308207 DOI: 10.1016/J.Tcb.2004.07.004  0.52
2004 Piehl M, Tulu US, Wadsworth P, Cassimeris L. Centrosome maturation: measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1. Proceedings of the National Academy of Sciences of the United States of America. 101: 1584-8. PMID 14747658 DOI: 10.1073/Pnas.0308205100  0.503
2003 Tulu US, Rusan NM, Wadsworth P. Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells. Current Biology : Cb. 13: 1894-9. PMID 14588246 DOI: 10.1016/J.Cub.2003.10.002  0.585
2003 Wadsworth P. Cell biology. Persistence pays. Science (New York, N.Y.). 300: 1675-7. PMID 12805528 DOI: 10.1126/Science.1086055  0.424
2002 Rusan NM, Tulu US, Fagerstrom C, Wadsworth P. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. The Journal of Cell Biology. 158: 997-1003. PMID 12235119 DOI: 10.1083/Jcb.200204109  0.576
2002 Landen JW, Lang R, McMahon SJ, Rusan NM, Yvon AM, Adams AW, Sorcinelli MD, Campbell R, Bonaccorsi P, Ansel JC, Archer DR, Wadsworth P, Armstrong CA, Joshi HC. Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma. Cancer Research. 62: 4109-14. PMID 12124349  0.333
2002 Yvon AM, Walker JW, Danowski B, Fagerstrom C, Khodjakov A, Wadsworth P. Centrosome reorientation in wound-edge cells is cell type specific. Molecular Biology of the Cell. 13: 1871-80. PMID 12058055 DOI: 10.1091/Mbc.01-11-0539  0.548
2002 Wadsworth P. Focusing on Cells Cell. 111: 445-446. DOI: 10.1016/S0092-8674(02)01117-0  0.423
2001 Danowski BA, Khodjakov A, Wadsworth P. Centrosome behavior in motile HGF-treated PtK2 cells expressing GFP-gamma tubulin. Cell Motility and the Cytoskeleton. 50: 59-68. PMID 11746672 DOI: 10.1002/Cm.1041  0.552
2001 Yvon AM, Gross DJ, Wadsworth P. Antagonistic forces generated by myosin II and cytoplasmic dynein regulate microtubule turnover, movement, and organization in interphase cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 8656-61. PMID 11438687 DOI: 10.1073/Pnas.141224198  0.492
2001 Rusan NM, Fagerstrom CJ, Yvon AM, Wadsworth P. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin. Molecular Biology of the Cell. 12: 971-80. PMID 11294900 DOI: 10.1091/Mbc.12.4.971  0.503
2000 Yvon AM, Wadsworth P. Region-specific microtubule transport in motile cells. The Journal of Cell Biology. 151: 1003-12. PMID 11086002 DOI: 10.1083/Jcb.151.5.1003  0.493
1999 Yvon AM, Wadsworth P, Jordan MA. Taxol suppresses dynamics of individual microtubules in living human tumor cells. Molecular Biology of the Cell. 10: 947-59. PMID 10198049 DOI: 10.1091/Mbc.10.4.947  0.564
1999 Wadsworth P. Regional regulation of microtubule dynamics in polarized, motile cells. Cell Motility and the Cytoskeleton. 42: 48-59. PMID 9915584 DOI: 10.1002/(Sici)1097-0169(1999)42:1<48::Aid-Cm5>3.0.Co;2-8  0.55
1999 Wadsworth P. Microinjection of mitotic cells. Methods in Cell Biology. 61: 219-31. PMID 9891317 DOI: 10.1016/S0091-679X(08)61983-4  0.423
1998 McMeekan J, Wadsworth P. Functional assays to identify and characterize regulators of microtubule behavior. Biotechniques. 24: 870-6. PMID 9591140 DOI: 10.2144/98245Rr04  0.525
1996 Wadsworth P, Bottaro DP. Microtubule dynamic turnover is suppressed during polarization and stimulated in hepatocyte growth factor scattered Madin-Darby canine kidney epithelial cells. Cell Motility and the Cytoskeleton. 35: 225-36. PMID 8913643 DOI: 10.1002/(Sici)1097-0169(1996)35:3<225::Aid-Cm5>3.0.Co;2-7  0.519
1996 Shelden E, Wadsworth P. Stimulation of microtubule dynamic turnover in living cells treated with okadaic acid. Cell Motility and the Cytoskeleton. 35: 24-34. PMID 8874963 DOI: 10.1002/(Sici)1097-0169(1996)35:1<24::Aid-Cm2>3.0.Co;2-I  0.529
1995 Dhamodharan R, Jordan MA, Thrower D, Wilson L, Wadsworth P. Vinblastine suppresses dynamics of individual microtubules in living interphase cells. Molecular Biology of the Cell. 6: 1215-29. PMID 8534917 DOI: 10.1091/Mbc.6.9.1215  0.551
1995 Dhamodharan R, Wadsworth P. Modulation of microtubule dynamic instability in vivo by brain microtubule associated proteins. Journal of Cell Science. 108: 1679-89. PMID 7615685 DOI: 10.7275/R5Qv3Jr9  0.409
1995 Vasquez R, Howell B, Yvon A, Wadsworth P, Cassimeris L. Nanomolar Nocodazole Puts The Brakes On Microtubule Dynamic Instability In-Vivo Molecular Biology of the Cell. 6. DOI: 10.7275/R50C4T0S  0.449
1993 Wadsworth P. Mitosis: spindle assembly and chromosome motion. Current Opinion in Cell Biology. 5: 123-8. PMID 8448024 DOI: 10.1016/S0955-0674(05)80017-1  0.464
1993 Shelden E, Wadsworth P. Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific. The Journal of Cell Biology. 120: 935-45. PMID 8432733 DOI: 10.1083/Jcb.120.4.935  0.569
1993 Zhang D, Wadsworth P, Hepler PK. Dynamics of microfilaments are similar, but distinct from microtubules during cytokinesis in living, dividing plant cells Cell Motility and the Cytoskeleton. 24: 151-155. DOI: 10.1002/Cm.970240302  0.58
1992 Shelden E, Wadsworth P. Microinjection of biotin-tubulin into anaphase cells induces transient elongation of kinetochore microtubules and reversal of chromosome-to-pole motion. The Journal of Cell Biology. 116: 1409-20. PMID 1541637 DOI: 10.1083/Jcb.116.6.1409  0.523
1992 Shelden E, Wadsworth P. Visualization of Microtubules in Living Cells - Microtubule Dynamics are Cell Type Specific Molecular Biology of the Cell. 3. DOI: 10.7275/R5Sn075C  0.517
1992 Zhang DH, Wadsworth P, Hepler PK. Modulation of anaphase spindle microtubule structure in stamen hair cells of Tradescantia by calcium and related agents Journal of Cell Science. 102: 79-89. DOI: 10.7275/R5Nv9Gf3  0.349
1991 Wise D, Cassimeris L, Rieder CL, Wadsworth P, Salmon ED. Chromosome fiber dynamics and congression oscillations in metaphase PtK2 cells at 23 degrees C. Cell Motility and the Cytoskeleton. 18: 131-42. PMID 2013109 DOI: 10.1002/Cm.970180208  0.454
1991 Amin-Hanjani S, Wadsworth P. Inhibition of spindle elongation by taxol. Cell Motility and the Cytoskeleton. 20: 136-44. PMID 1684311 DOI: 10.1002/Cm.970200206  0.586
1990 Zhang D, Wadsworth P, Hepler PK. Microtubule dynamics in living dividing plant cells: confocal imaging of microinjected fluorescent brain tubulin. Proceedings of the National Academy of Sciences of the United States of America. 87: 8820-4. PMID 11607116 DOI: 10.1073/Pnas.87.22.8820  0.479
1990 Shelden E, Wadsworth P. Interzonal microtubules are dynamic during spindle elongation. Journal of Cell Science. 97: 273-81. PMID 2277093 DOI: 10.7275/R58P5Xqd  0.591
1990 Wadsworth P, McGrail M. Interphase microtubule dynamics are cell type-specific. Journal of Cell Science. 95: 23-32. PMID 2190995 DOI: 10.7275/R5Bg2M6C  0.531
1990 Wadsworth P, Shelden E. Microtubule assembly in the mitotic spindle Annals of the New York Academy of Sciences. 582: 312-313. DOI: 10.1111/J.1749-6632.1990.Tb21695.X  0.496
1989 Wadsworth P, Shelden E, Rupp G, Rieder CL. Biotin-tubulin incorporates into kinetochore fiber microtubules during early but not late anaphase. The Journal of Cell Biology. 109: 2257-65. PMID 2681228 DOI: 10.1083/Jcb.109.5.2257  0.44
1988 Wadsworth P, Salmon ED. Spindle microtubule dynamics: modulation by metabolic inhibitors. Cell Motility and the Cytoskeleton. 11: 97-105. PMID 3056623 DOI: 10.1002/Cm.970110203  0.568
1987 Wadsworth P. Microinjected carboxylated beads move predominantly poleward in sea urchin eggs. Cell Motility and the Cytoskeleton. 8: 293-301. PMID 2891449 DOI: 10.1002/Cm.970080402  0.557
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