Year |
Citation |
Score |
2024 |
McGinn M, Rabender C, Mikkelsen R, Yakovlev V. Hepatocyte-derived extracellular vesicles regulate liver regeneration after partial hepatectomy. Biorxiv : the Preprint Server For Biology. PMID 38979255 DOI: 10.1101/2024.06.25.600679 |
0.683 |
|
2022 |
Clark GC, Hampton JD, Koblinski JE, Quinn B, Mahmoodi S, Metcalf O, Guo C, Peterson E, Fisher PB, Farrell NP, Wang XY, Mikkelsen RB. Radiation induces ESCRT pathway dependent CD44v3 extracellular vesicle production stimulating pro-tumor fibroblast activity in breast cancer. Frontiers in Oncology. 12: 913656. PMID 36106109 DOI: 10.3389/fonc.2022.913656 |
0.39 |
|
2021 |
Rabender CS, Mezzaroma E, Yakovlev VA, Mauro AG, Bonaventura A, Abbate A, Mikkelsen RB. Mitigation of Radiation-Induced Lung and Heart Injuries in Mice by Oral Sepiapterin after Irradiation. Radiation Research. 195: 463-473. PMID 33822229 DOI: 10.1667/RADE-20-00249.1 |
0.718 |
|
2019 |
Singh S, Vaughan CA, Rabender C, Mikkelsen R, Deb S, Palit Deb S. DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2. Jci Insight. PMID 31527309 DOI: 10.1172/Jci.Insight.128194 |
0.715 |
|
2018 |
Rabender CS, Bruno N, Alam A, Sundaresan G, Zweit J, Mikkelsen RB. Sepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular Normalization. The Journal of Pharmacology and Experimental Therapeutics. PMID 29581154 DOI: 10.1124/Jpet.117.245258 |
0.766 |
|
2017 |
Rabender CS, Gobalakrishnan S, Wang L, Zweit J, Mikkelsen RB. Abstract 5196: Recoupling nitric oxide synthetase to normalize tumor vasculature and enhance tumor radiosensitivity and anti-tumor drug uptake Cancer Research. 77: 5196-5196. DOI: 10.1158/1538-7445.Am2017-5196 |
0.739 |
|
2017 |
Serrano N, Blue J, Alam A, Rabender CS, Weiss E, Anscher MS, Mikkelsen RB, Yakovlev VA. Abstract 3800: Analysis of circulating tumor exosomes: their ability to serve as a biomarker for recurrence in lung cancer Cancer Research. 77: 3800-3800. DOI: 10.1158/1538-7445.Am2017-3800 |
0.738 |
|
2016 |
Rabender C, Mezzaroma E, Mauro AG, Mullangi R, Abbate A, Anscher M, Hart B, Mikkelsen R. IPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects. Radiation Research. 186: 478-488. PMID 27841740 DOI: 10.1667/Rr14403.2 |
0.724 |
|
2016 |
Serrano N, Alam A, Rabender C, Weiss E, Anscher MS, Mikkelsen RB, Yakovlev V. Analysis of Circulating Tumor Exosomes: Their Role in the Tissue Microenvironment and Ability to Serve as a Biomarker for Recurrence in Lung Cancer. International Journal of Radiation Oncology, Biology, Physics. 96: E565-E566. PMID 27675031 DOI: 10.1016/J.Ijrobp.2016.06.2044 |
0.751 |
|
2016 |
Rabender C, Bruno N, Mikkelsen RB. Abstract 3383: Tumor vasculature normalization by recoupling nitric oxide synthase with a tetrahydrobiopterin precursor Cancer Research. 76: 3383-3383. DOI: 10.1158/1538-7445.Am2016-3383 |
0.771 |
|
2015 |
Alam A, Mukhopadhyay ND, Ning Y, Reshko LB, Cardnell RJ, Alam O, Rabender CS, Yakovlev VA, Walker L, Anscher MS, Mikkelsen RB. A Preliminary Study on Racial Differences in HMOX1, NFE2L2, and TGFβ1 Gene Polymorphisms and Radiation-Induced Late Normal Tissue Toxicity. International Journal of Radiation Oncology, Biology, Physics. 93: 436-43. PMID 26238954 DOI: 10.1016/J.Ijrobp.2015.05.049 |
0.711 |
|
2015 |
Liu R, Zhang L, Yang J, Zhang X, Mikkelsen R, Song S, Zhou H. HIV Protease Inhibitors Sensitize Human Head and Neck Squamous Carcinoma Cells to Radiation by Activating Endoplasmic Reticulum Stress. Plos One. 10: e0125928. PMID 25933118 DOI: 10.1371/Journal.Pone.0125928 |
0.321 |
|
2015 |
Rabender CS, Alam A, Sundaresan G, Cardnell RJ, Yakovlev VA, Mukhopadhyay ND, Graves P, Zweit J, Mikkelsen RB. The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression. Molecular Cancer Research : McR. 13: 1034-43. PMID 25724429 DOI: 10.1158/1541-7786.Mcr-15-0057-T |
0.767 |
|
2015 |
Rabender C, Alam A, Waters M, Mikkelsen R. Abstract 1210: Biopterin metabolism drives tumor progression Cancer Research. 75: 1210-1210. DOI: 10.1158/1538-7445.Am2015-1210 |
0.773 |
|
2014 |
Wallner PE, Anscher MS, Barker CA, Bassetti M, Bristow RG, Cha YI, Dicker AP, Formenti SC, Graves EE, Hahn SM, Hei TK, Kimmelman AC, Kirsch DG, Kozak KR, Lawrence TS, ... ... Mikkelsen RB, et al. Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary. International Journal of Radiation Oncology, Biology, Physics. 88: 11-7. PMID 24246724 DOI: 10.1016/J.Ijrobp.2013.09.040 |
0.314 |
|
2014 |
Mikkelsen R, Rabender C, Graves P, Anscher M. Induction of HO-1 and CO Synthesis Radiosensitizes Tumor Epithelial Cells With CO Acting as a NO Mimetic International Journal of Radiation Oncology*Biology*Physics. 90: S105. DOI: 10.1016/J.Ijrobp.2014.05.517 |
0.735 |
|
2013 |
Cardnell RJ, Rabender CS, Ross GR, Guo C, Howlett EL, Alam A, Wang XY, Akbarali HI, Mikkelsen RB. Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer. The Journal of Pharmacology and Experimental Therapeutics. 347: 117-25. PMID 23912334 DOI: 10.1124/Jpet.113.203828 |
0.73 |
|
2013 |
Alam A, Rabender C, Mikkelsen R. Abstract 443: PKC epsilon is activated by ionizing radiation in a reactive nitrogen species dependent manner in tumor endothelial cells. Cancer Research. 73: 443-443. DOI: 10.1158/1538-7445.Am2013-443 |
0.774 |
|
2012 |
Chris R, Mikkelsen R. Abstract 2057: Tumor suppressor effects of tetrahydrobiopterin are mediated through beta-catenin in breast cancer cells Cancer Research. 72: 2057-2057. DOI: 10.1158/1538-7445.Am2012-2057 |
0.487 |
|
2012 |
Mikkelsen R, Alam A, Cardnell R, Howlett E, Reshko L, Walker L, Ning Y, Anscher M. Polymorphisms in Genes Involved in Nitric Oxide (NO) Signaling and the Risk for Late Normal Tissue Injury From Radiation Therapy (RT) International Journal of Radiation Oncology*Biology*Physics. 84: S682. DOI: 10.1016/J.Ijrobp.2012.07.1822 |
0.346 |
|
2011 |
Cardnell RJ, Mikkelsen RB. Nitric oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous carcinoma xenografts. Plos One. 6: e20147. PMID 21647438 DOI: 10.1371/Journal.Pone.0020147 |
0.443 |
|
2011 |
Rabender CS, Mikkelsen R. Abstract 4062: Nitric Oxide synthase dysregulation in solid tumors: The therapeutic potential of tetrahydrobiopterin Cancer Research. 71: 4062-4062. DOI: 10.1158/1538-7445.Am2011-4062 |
0.772 |
|
2010 |
Yakovlev VA, Mikkelsen RB. Protein tyrosine nitration in cellular signal transduction pathways. Journal of Receptor and Signal Transduction Research. 30: 420-9. PMID 20843272 DOI: 10.3109/10799893.2010.513991 |
0.313 |
|
2010 |
Yakovlev VA, Rabender CS, Sankala H, Gauter-Fleckenstein B, Fleckenstein K, Batinic-Haberle I, Jackson I, Vujaskovic Z, Anscher MS, Mikkelsen RB, Graves PR. Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+). International Journal of Radiation Oncology, Biology, Physics. 78: 547-54. PMID 20584581 DOI: 10.1016/J.Ijrobp.2010.03.037 |
0.72 |
|
2010 |
Wang J, Lin P, Mikkelsen RB, Gewirtz D, Anscher MS, Graves PR. Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin Cancer Research. 70: 1400-1400. DOI: 10.1158/1538-7445.Am10-1400 |
0.445 |
|
2010 |
Rabender C, Mikkelsen R. Abstract 1324: Modulation of IR induced NFKB activity by manipulation of NOS coupling Cancer Research. 70: 1324-1324. DOI: 10.1158/1538-7445.Am10-1324 |
0.749 |
|
2010 |
Robert CJG, Mikkelsen RB. Abstract 1321: ERK1/2 show different activity profilesin vitroandin vivosubsequent to NOS inhibition Cancer Research. 70: 1321-1321. DOI: 10.1158/1538-7445.Am10-1321 |
0.445 |
|
2009 |
Graves P, Van Meter T, Rosenberg E, Mikkelsen R. The Role of Nitric Oxide Synthase and Heme Oxygenase I in Radiation-induced Lung Injury International Journal of Radiation Oncology*Biology*Physics. 75: S172-S173. DOI: 10.1016/J.Ijrobp.2009.07.403 |
0.391 |
|
2009 |
Mikkelsen R, Cardnell R. Nitric Oxide Synthase Inhibition Enhances In Vivo the Radiation Response of Squamous Carcinomas International Journal of Radiation Oncology*Biology*Physics. 75: S70-S71. DOI: 10.1016/J.Ijrobp.2009.07.178 |
0.356 |
|
2008 |
Yakovlev V, Fleckenstein K, Graves P, Jackson I, Vujaskovic Z, Mikkelsen R. Phasic Changes in Protein Tyrosine Nitration and Expression of Key Regulatory Proteins in the Rodent Lung Following a Radiation Exposure International Journal of Radiation Oncology*Biology*Physics. 72: S22-S23. DOI: 10.1016/J.Ijrobp.2008.06.816 |
0.339 |
|
2007 |
Yakovlev VA, Barani IJ, Rabender CS, Black SM, Leach JK, Graves PR, Kellogg GE, Mikkelsen RB. Tyrosine nitration of IkappaBalpha: a novel mechanism for NF-kappaB activation. Biochemistry. 46: 11671-83. PMID 17910475 DOI: 10.1021/Bi701107Z |
0.704 |
|
2005 |
Barrett DM, Black SM, Todor H, Schmidt-Ullrich RK, Dawson KS, Mikkelsen RB. Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation. The Journal of Biological Chemistry. 280: 14453-61. PMID 15684422 DOI: 10.1074/Jbc.M411523200 |
0.38 |
|
2004 |
Mikkelsen R. Redox signaling mechanisms and radiation-induced bystander effects. Human & Experimental Toxicology. 23: 75-79. PMID 15070064 DOI: 10.1191/0960327104Ht421Oa |
0.338 |
|
2003 |
Mikkelsen RB, Wardman P. Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene. 22: 5734-54. PMID 12947383 DOI: 10.1038/Sj.Onc.1206663 |
0.386 |
|
2003 |
Koo DT, Mikkelsen RB. Modulation of radiation-induced p53 Ser-15 phosphorylation by nitric oxide International Journal of Radiation Oncology Biology Physics. 57. DOI: 10.1016/S0360-3016(03)01159-3 |
0.36 |
|
2002 |
Leach JK, Black SM, Schmidt-Ullrich RK, Mikkelsen RB. Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation. The Journal of Biological Chemistry. 277: 15400-6. PMID 11856735 DOI: 10.1074/Jbc.M110309200 |
0.418 |
|
2001 |
Lammering G, Hewit T, Contessa J, Hawkins W, Lin P, Valerie K, Mikkelsen R, Dent P, Schmidt-Ullrich R. EGFR and its mutant EGFRvIII as modulators of tumor cell radiosensitivity International Journal of Radiation Oncology*Biology*Physics. 51: 103. DOI: 10.1016/S0360-3016(01)02012-0 |
0.31 |
|
1996 |
Schmidt-Ullrich R, Mikkelsen R, Valerie K, Todd D, Kavanagh B, Contessa J, Rorrer K, Chen P. 134 Molecular mechanisms of radiation-induced cell proliferation in human carcinoma cells International Journal of Radiation Oncology*Biology*Physics. 36: 225. DOI: 10.1016/S0360-3016(97)85475-2 |
0.35 |
|
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