| Year |
Citation |
Score |
| 2024 |
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, ... ... Nepom GT, et al. Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue. Nature Communications. 15: 1564. PMID 38378682 DOI: 10.1038/s41467-024-45012-9 |
0.665 |
|
| 2023 |
Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K. Proinflammatory islet antigen reactive CD4 T cells are linked with response to alefacept in type 1 diabetes. Jci Insight. PMID 37751304 DOI: 10.1172/jci.insight.167881 |
0.308 |
|
| 2023 |
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, ... ... Nepom GT, et al. FOXP3 regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues. Biorxiv : the Preprint Server For Biology. PMID 36909599 DOI: 10.1101/2023.02.26.529772 |
0.66 |
|
| 2021 |
Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco MG, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, ... ... Nepom GT, et al. Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes. Jci Insight. 6. PMID 34806648 DOI: 10.1172/jci.insight.151349 |
0.306 |
|
| 2020 |
Diggins KE, Serti E, Muir VS, Rosasco MG, Lu T, Balmas E, Nepom GT, Long SA, Linsley PS. Exhausted-like CD8 T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects. Jci Insight. PMID 33351781 DOI: 10.1172/jci.insight.142680 |
0.308 |
|
| 2019 |
Chow IT, Gates TJ, Papadopoulos GK, Moustakas AK, Kolawole EM, Notturno RJ, McGinty JW, Torres-Chinn N, James EA, Greenbaum C, Nepom GT, Evavold BD, Kwok WW. Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes. Science Advances. 5: eaaw9336. PMID 31457096 DOI: 10.1126/Sciadv.Aaw9336 |
0.329 |
|
| 2019 |
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, et al. Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. Journal of Immunology (Baltimore, Md. : 1950). PMID 30683697 DOI: 10.4049/Jimmunol.1801425 |
0.333 |
|
| 2017 |
Yang J, Wen X, Xu H, Torres-Chinn N, Speake C, Greenbaum CJ, Nepom GT, Kwok WW. Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28550202 DOI: 10.4049/jimmunol.1601570 |
0.303 |
|
| 2016 |
Long SA, Thorpe J, DeBerg HA, Gersuk V, Eddy J, Harris KM, Ehlers M, Herold KC, Nepom GT, Linsley PS. Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes. Science Immunology. 1. PMID 28664195 DOI: 10.1126/Sciimmunol.Aai7793 |
0.325 |
|
| 2014 |
Durinovic-Belló I, Gersuk VH, Ni C, Wu R, Thorpe J, Jospe N, Sanda S, Greenbaum CJ, Nepom GT. Avidity-dependent programming of autoreactive T cells in T1D. Plos One. 9: e98074. PMID 24844227 DOI: 10.1371/journal.pone.0098074 |
0.335 |
|
| 2013 |
Dahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y. Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope. Journal of Autoimmunity. 47: 83-93. PMID 24090977 DOI: 10.1016/J.Jaut.2013.08.009 |
0.322 |
|
| 2013 |
Bollyky PL, Vernon RB, Falk BA, Preisinger A, Gooden MD, Nepom GT, Gebe JA. IL-10 induction from implants delivering pancreatic islets and hyaluronan. Journal of Diabetes Research. 2013: 342479. PMID 23971054 DOI: 10.1155/2013/342479 |
0.576 |
|
| 2013 |
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, ... Nepom G, et al. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice. Plos One. 8: e54712. PMID 23405091 DOI: 10.1371/Journal.Pone.0054712 |
0.35 |
|
| 2012 |
Vernon RB, Preisinger A, Gooden MD, D'Amico LA, Yue BB, Bollyky PL, Kuhr CS, Hefty TR, Nepom GT, Gebe JA. Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor. Cell Transplantation. 21: 2099-110. PMID 23231959 DOI: 10.3727/096368912X636786 |
0.496 |
|
| 2012 |
Nepom GT. MHC class II tetramers. Journal of Immunology (Baltimore, Md. : 1950). 188: 2477-82. PMID 22389204 DOI: 10.4049/jimmunol.1102398 |
0.315 |
|
| 2012 |
Evanko SP, Potter-Perigo S, Bollyky PL, Nepom GT, Wight TN. Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 90-100. PMID 22155153 DOI: 10.1016/j.matbio.2011.10.004 |
0.574 |
|
| 2011 |
Snir O, Rieck M, Gebe JA, Yue BB, Rawlings CA, Nepom G, Malmström V, Buckner JH. Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients. Arthritis and Rheumatism. 63: 2873-83. PMID 21567378 DOI: 10.1002/Art.30445 |
0.385 |
|
| 2011 |
Bollyky PL, Wu RP, Falk BA, Lord JD, Long SA, Preisinger A, Teng B, Holt GE, Standifer NE, Braun KR, Xie CF, Samuels PL, Vernon RB, Gebe JA, Wight TN, ... Nepom GT, et al. ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors. Proceedings of the National Academy of Sciences of the United States of America. 108: 7938-43. PMID 21518860 DOI: 10.1073/Pnas.1017360108 |
0.622 |
|
| 2010 |
Bollyky PL, Evanko SP, Wu RP, Potter-Perigo S, Long SA, Kinsella B, Reijonen H, Guebtner K, Teng B, Chan CK, Braun KR, Gebe JA, Nepom GT, Wight TN. Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse. Cellular & Molecular Immunology. 7: 211-20. PMID 20228832 DOI: 10.1038/Cmi.2010.9 |
0.588 |
|
| 2010 |
Honeyman MC, Stone NL, Falk BA, Nepom G, Harrison LC. Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens. Journal of Immunology (Baltimore, Md. : 1950). 184: 2204-10. PMID 20083660 DOI: 10.4049/Jimmunol.0900709 |
0.392 |
|
| 2010 |
Durinovic-Belló I, Wu RP, Gersuk VH, Sanda S, Shilling HG, Nepom GT. Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin. Genes and Immunity. 11: 188-93. PMID 20054344 DOI: 10.1038/gene.2009.108 |
0.331 |
|
| 2010 |
Song Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, Love JC. On-chip activation and subsequent detection of individual antigen-specific T cells. Analytical Chemistry. 82: 473-7. PMID 20000848 DOI: 10.1021/Ac9024363 |
0.346 |
|
| 2010 |
Gebe J, Yue B, Rieck M, Preisinger A, James E, Rawlings C, Stone B, Buckner J, Nepom G. Autoantigen T Cell Immune Responses Observed in the DR0401/DR0404 MHC-generated T Cell Repertoire that are Absent in the Homozygous DR0401 or DR0404 Restricted T Cell Repertoire Clinical Immunology. 135: S122. DOI: 10.1016/J.Clim.2010.03.367 |
0.4 |
|
| 2009 |
Bollyky PL, Falk BA, Long SA, Preisinger A, Braun KR, Wu RP, Evanko SP, Buckner JH, Wight TN, Nepom GT. CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta. Journal of Immunology (Baltimore, Md. : 1950). 183: 2232-41. PMID 19635906 DOI: 10.4049/jimmunol.0900191 |
0.591 |
|
| 2009 |
Gebe JA, Yue BB, Unrath KA, Falk BA, Nepom GT. Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 183: 59-65. PMID 19535636 DOI: 10.4049/Jimmunol.0804046 |
0.36 |
|
| 2009 |
Standifer NE, Burwell EA, Gersuk VH, Greenbaum CJ, Nepom GT. Changes in autoreactive T cell avidity during type 1 diabetes development. Clinical Immunology (Orlando, Fla.). 132: 312-20. PMID 19482555 DOI: 10.1016/j.clim.2009.04.013 |
0.301 |
|
| 2009 |
Bollyky PL, Falk BA, Wu RP, Buckner JH, Wight TN, Nepom GT. Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells. Journal of Leukocyte Biology. 86: 567-72. PMID 19401397 DOI: 10.1189/jlb.0109001 |
0.611 |
|
| 2009 |
Bollyky PL, Bice JB, Sweet IR, Falk BA, Gebe JA, Clark AE, Gersuk VH, Aderem A, Hawn TR, Nepom GT. The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury. Plos One. 4: e5063. PMID 19357791 DOI: 10.1371/Journal.Pone.0005063 |
0.509 |
|
| 2009 |
Long SA, Walker MR, Rieck M, James E, Kwok WW, Sanda S, Pihoker C, Greenbaum C, Nepom GT, Buckner JH. Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. European Journal of Immunology. 39: 612-20. PMID 19180473 DOI: 10.1002/eji.200838819 |
0.354 |
|
| 2009 |
Standifer N, Burwell E, Nepom G. S.48. Longitudinal Dynamics of CD4+T Cell Responses to an Insulin Peptide in Healthy, Autoantibody-positive and Type 1 Diabetic Subjects Clinical Immunology. 131: S145-S146. DOI: 10.1016/J.Clim.2009.03.429 |
0.343 |
|
| 2009 |
Durinovic-Bello I, Wu R, Sanda S, Nepom G. F.69. Selection of Antigen Specific Autoreactive T Cells is Influenced by INS-VNTR Genotype Clinical Immunology. 131: S112. DOI: 10.1016/J.Clim.2009.03.329 |
0.349 |
|
| 2009 |
Bollyky P, Falk B, Long SA, Wu R, Evanko S, Buckner J, Wight T, Nepom G. Tissue Environment Modulates FoxP3+Regulatory T Cells (Treg) Through Interactions with Extracellular Matrix Clinical Immunology. 131: S33. DOI: 10.1016/J.Clim.2009.03.091 |
0.605 |
|
| 2008 |
Laughlin E, Burke G, Pugliese A, Falk B, Nepom G. Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation. Clinical Immunology (Orlando, Fla.). 128: 23-30. PMID 18455963 DOI: 10.1016/J.Clim.2008.03.459 |
0.409 |
|
| 2008 |
Gebe JA, Unrath KA, Yue BB, Miyake T, Falk BA, Nepom GT. Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice. Journal of Autoimmunity. 30: 197-206. PMID 17949947 DOI: 10.1016/J.Jaut.2007.08.001 |
0.325 |
|
| 2008 |
Bollyky PL, Falk B, Jane BH, Stephen EP, Wight TT, Nepom GT. Intact hyaluronan promotes maintenance of immune tolerance Matrix Biology. 27: 15-16. DOI: 10.1016/j.matbio.2008.09.243 |
0.519 |
|
| 2008 |
Bollyky P, Wu R, Falk B, Wight T, Buckner J, Nepom G. OR.31. CD44 Cross-linking Potently Induces FoxP3 and Promotes CD4+CD25+ Regulatory T Cell Mediated Suppression Clinical Immunology. 127: S14. DOI: 10.1016/J.Clim.2008.03.036 |
0.607 |
|
| 2008 |
Standifer N, Nepom G. OR.9. A Shift in Autoreactive CD4 T Cell Avidity Preceding Diagnosis with Type 1 Diabetes is Correlated with the Outgrowth of Distinct T Cell Clonotypes Clinical Immunology. 127: S7. DOI: 10.1016/J.Clim.2008.03.014 |
0.382 |
|
| 2007 |
Bollyky PL, Lord JD, Masewicz SA, Evanko SP, Buckner JH, Wight TN, Nepom GT. Cutting edge: high molecular weight hyaluronan promotes the suppressive effects of CD4+CD25+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 744-7. PMID 17617562 |
0.59 |
|
| 2007 |
Laughlin EM, Miller JD, James E, Fillos D, Ibegbu CC, Mittler RS, Akondy R, Kwok W, Ahmed R, Nepom G. Antigen-specific CD4+ T cells recognize epitopes of protective antigen following vaccination with an anthrax vaccine. Infection and Immunity. 75: 1852-60. PMID 17283103 DOI: 10.1128/Iai.01814-06 |
0.425 |
|
| 2007 |
Bollyky P, Nepom G, Buckner J, Masewicz S, Lord J, Evanko S, Wight T. High Molecular Weight Hyaluronan Promotes the Suppressive Effects of CD4+CD25+ T-reg Clinical Immunology. 123: S118. DOI: 10.1016/J.Clim.2007.03.515 |
0.597 |
|
| 2007 |
Standifer N, Nepom G. Evidence for an Increase in the Functional Avidity of the GAD-reactive CD4+ T Cell Population Prior to Diabetes Onset Clinical Immunology. 123: S67. DOI: 10.1016/J.Clim.2007.03.369 |
0.371 |
|
| 2007 |
Durinovic-Bello I, Pratt N, Masewicz SA, Nepom G. Protective Versus Aggressive T Cell Responses to the Major Proinsulin73–90 Epitope in Beta-Islet Cell Autoimmunity Clinical Immunology. 123: S27. DOI: 10.1016/J.Clim.2007.03.245 |
0.337 |
|
| 2006 |
Durinovic-Belló I, Rosinger S, Olson JA, Congia M, Ahmad RC, Rickert M, Hampl J, Kalbacher H, Drijfhout JW, Mellins ED, Al Dahouk S, Kamradt T, Maeurer MJ, Nhan C, Roep BO, ... ... Nepom GT, et al. DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype. Proceedings of the National Academy of Sciences of the United States of America. 103: 11683-8. PMID 16868084 DOI: 10.1073/Pnas.0603682103 |
0.362 |
|
| 2006 |
Öling V, Marttila J, Ilonen J, Kwok WW, Nepom G, Knip M, Simell O, Reijonen H. Corrigendum to: “GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects” [Journal of Autoimmunity 25 (2005) 235–243] Journal of Autoimmunity. 27: 69. DOI: 10.1016/J.Jaut.2006.05.002 |
0.413 |
|
| 2006 |
Standifer N, Beeton C, Chandy KG, Nepom G. Su.36. Gad-Reactive, Effector Memory Cd4+ T-Cells Cultured from Type 1 Diabetic Patients Express Increased Levels of the Voltage-Gated Potassium Channel Kv1.3: a Potential Therapeutic Target Clinical Immunology. 119: S172. DOI: 10.1016/J.Clim.2006.04.463 |
0.329 |
|
| 2006 |
Masewicz S, Walker M, VanLandeghan M, Buckner J, Nepom G. Su.20. Analysis of the Cd4 Effector T-Cell Response to Regulation in Diabetes Mellitus Clinical Immunology. 119: S166. DOI: 10.1016/J.Clim.2006.04.447 |
0.383 |
|
| 2006 |
Walker M, Carson B, Ziegler S, Nepom G, Buckner J. OR.45. Induction of Autoantigen-Specific Cd4+Cd25+ Regulatory T‐Cells In Vitro Clinical Immunology. 119: S20-S21. DOI: 10.1016/J.Clim.2006.04.201 |
0.332 |
|
| 2005 |
Oling V, Marttila J, Ilonen J, Kwok WW, Nepom G, Knip M, Simell O, Reijonen H. GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects. Journal of Autoimmunity. 25: 235-43. PMID 16263242 DOI: 10.1016/J.Jaut.2005.09.018 |
0.382 |
|
| 2005 |
Mallone R, Kochik SA, Reijonen H, Carson B, Ziegler SF, Kwok WW, Nepom GT. Functional avidity directs T-cell fate in autoreactive CD4+ T cells. Blood. 106: 2798-805. PMID 16030184 DOI: 10.1182/Blood-2004-12-4848 |
0.34 |
|
| 2005 |
Walker MR, Carson BD, Nepom GT, Ziegler SF, Buckner JH. De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4103-8. PMID 15753318 DOI: 10.1073/Pnas.0407691102 |
0.343 |
|
| 2004 |
Reijonen H, Mallone R, Heninger AK, Laughlin EM, Kochik SA, Falk B, Kwok WW, Greenbaum C, Nepom GT. GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes. Diabetes. 53: 1987-94. PMID 15277377 |
0.311 |
|
| 2004 |
Shams H, Klucar P, Weis SE, Lalvani A, Moonan PK, Safi H, Wizel B, Ewer K, Nepom GT, Lewinsohn DM, Andersen P, Barnes PF. Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles. Journal of Immunology (Baltimore, Md. : 1950). 173: 1966-77. PMID 15265931 DOI: 10.4049/Jimmunol.173.3.1966 |
0.304 |
|
| 2004 |
Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH. Extensive replicative capacity of human central memory T cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 6675-83. PMID 15153483 DOI: 10.4049/Jimmunol.172.11.6675 |
0.335 |
|
| 2004 |
Mallone R, Kochik SA, Laughlin EM, Gersuk VH, Reijonen H, Kwok WW, Nepom GT. Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells. Diabetes. 53: 971-7. PMID 15047612 |
0.337 |
|
| 2004 |
Mallone R, Nepom GT. MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete. Clinical Immunology (Orlando, Fla.). 110: 232-42. PMID 15047201 DOI: 10.1016/j.clim.2003.11.004 |
0.358 |
|
| 2003 |
Reijonen H, Kwok WW, Nepom GT. Detection of CD4+ autoreactive T cells in T1D using HLA class II tetramers. Annals of the New York Academy of Sciences. 1005: 82-7. PMID 14679042 |
0.361 |
|
| 2003 |
Maus MV, Riley JL, Kwok WW, Nepom GT, June CH. HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells. Clinical Immunology (Orlando, Fla.). 106: 16-22. PMID 12584046 DOI: 10.1016/S1521-6616(02)00017-7 |
0.337 |
|
| 2002 |
Norrby-Teglund A, Nepom GT, Kotb M. Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles. European Journal of Immunology. 32: 2570-7. PMID 12207341 DOI: 10.1002/1521-4141(200209)32:9<2570::AID-IMMU2570>3.0.CO;2-E |
0.301 |
|
| 2002 |
Buckner JH, Holzer U, Novak EJ, Reijonen H, Kwok WW, Nepom GT. Defining antigen-specific responses with human MHC class II tetramers. The Journal of Allergy and Clinical Immunology. 110: 199-208. PMID 12170258 DOI: 10.1067/Mai.2002.125976 |
0.337 |
|
| 2002 |
Reijonen H, Novak EJ, Kochik S, Heninger A, Liu AW, Kwok WW, Nepom GT. Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects. Diabetes. 51: 1375-82. PMID 11978633 DOI: 10.2337/Diabetes.51.5.1375 |
0.33 |
|
| 2002 |
Masewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT. Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65. Autoimmunity. 34: 231-40. PMID 11905849 DOI: 10.3109/08916930109014692 |
0.339 |
|
| 2002 |
Nepom GT, Buckner JH, Novak EJ, Reichstetter S, Reijonen H, Gebe J, Wang R, Swanson E, Kwok WW. HLA class II tetramers: tools for direct analysis of antigen-specific CD4+ T cells. Arthritis and Rheumatism. 46: 5-12. PMID 11817608 DOI: 10.1002/1529-0131(200201)46:1<5::Aid-Art10063>3.0.Co;2-S |
0.312 |
|
| 2001 |
Gebe JA, Novak EJ, Kwok WW, Farr AG, Nepom GT, Buckner JH. T cell selection and differential activation on structurally related HLA-DR4 ligands. Journal of Immunology (Baltimore, Md. : 1950). 167: 3250-6. PMID 11544312 DOI: 10.4049/Jimmunol.167.6.3250 |
0.348 |
|
| 2001 |
Nepom GT. The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis. Rheumatic Diseases Clinics of North America. 27: 305-15. PMID 11396094 DOI: 10.1016/S0889-857X(05)70203-9 |
0.308 |
|
| 2001 |
Novak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT. Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset. International Immunology. 13: 799-806. PMID 11369708 DOI: 10.1093/Intimm/13.6.799 |
0.362 |
|
| 2001 |
Novak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW. Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens. Journal of Immunology (Baltimore, Md. : 1950). 166: 6665-70. PMID 11359821 DOI: 10.4049/Jimmunol.166.11.6665 |
0.322 |
|
| 2000 |
Novak EJ, Liu AW, Nepom GT, Kwok WW. MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen. The Journal of Clinical Investigation. 104: R63-7. PMID 10606632 DOI: 10.1172/Jci8476 |
0.337 |
|
| 1999 |
Beaty JS, Sukiennicki TL, Nepom GT. Allelic variation in transcription modulates MHC class II expression and function. Microbes and Infection / Institut Pasteur. 1: 919-27. PMID 10614010 DOI: 10.1016/S1286-4579(99)00225-7 |
0.719 |
|
| 1998 |
Hershberg RM, Cho DH, Youakim A, Bradley MB, Lee JS, Framson PE, Nepom GT. Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells Journal of Clinical Investigation. 102: 792-803. PMID 9710448 DOI: 10.1172/JCI3201 |
0.304 |
|
| 1998 |
Nepom GT, Kwok WW. Molecular basis for HLA-DQ associations with IDDM Diabetes. 47: 1177-1184. PMID 9703314 DOI: 10.2337/diab.47.8.1177 |
0.343 |
|
| 1998 |
Drover S, Kovats S, Masewicz S, Blum JS, Nepom GT. Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM. Human Immunology. 59: 77-86. PMID 9536430 DOI: 10.1016/S0198-8859(97)00263-2 |
0.303 |
|
| 1997 |
Hershberg RM, Framson PE, Cho DH, Lee LY, Kovats S, Beitz J, Blum JS, Nepom GT. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing. The Journal of Clinical Investigation. 100: 204-15. PMID 9202073 DOI: 10.1172/JCI119514 |
0.341 |
|
| 1996 |
Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ. Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. The Journal of Clinical Investigation. 98: 2597-603. PMID 8958223 DOI: 10.1172/Jci119079 |
0.323 |
|
| 1996 |
Bach J, Otto H, Rung G, Nepom G, Boitard C, van Endert P. Presentation of an autoantigenic (GAD65) peptide in IDDM by an HLA allele protecting from disease Human Immunology. 47: 151. DOI: 10.1016/0198-8859(96)85515-7 |
0.307 |
|
| 1996 |
Doherty DG, Koelle DM, Kwok WW, Masewicz S, Domeier ME, Nepom GT. Allelic variants of MHC class II Molecules can ACT as partial agonists of antigen-specific T cell responses Human Immunology. 47: 149. DOI: 10.1016/0198-8859(96)85506-6 |
0.326 |
|
| 1996 |
Kwok W, Koelle D, Nepom G. Interactions of peptide side chains with structurally complementary pockets in DQ molecules are critical for allele-specific peptide binding and T cell reactivity Human Immunology. 47: 17. DOI: 10.1016/0198-8859(96)84769-0 |
0.32 |
|
| 1996 |
Nepom GT, Sukiennicki T, Beaty JS. Allele-specific transcriptional regulation of HLA-DQB1 genes Human Immunology. 47: 12. DOI: 10.1016/0198-8859(96)84738-0 |
0.715 |
|
| 1995 |
Woolfrey AE, Nepom GT. Differential transcription elements direct expression of HLA-DQ genes. Clinical Immunology and Immunopathology. 74: 119-26. PMID 7828365 DOI: 10.1006/CLIN.1995.1018 |
0.304 |
|
| 1995 |
Beaty JS, West KA, Nepom GT. Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1 Molecular and Cellular Biology. 15: 4771-4782. PMID 7651394 DOI: 10.1128/MCB.15.9.4771 |
0.324 |
|
| 1995 |
Uchigata Y, Tokunaga K, Nepom G, Bannai M, Kuwata S, Dozio N, Benson EA, Ronningen KS, Spinas GA, Tadokoro K. Differential immunogenetic determinants of polyclonal insulin autoimmune syndrome (Hirata's disease) and monoclonal insulin autoimmune syndrome. Diabetes. 44: 1227-32. PMID 7556962 DOI: 10.2337/Diab.44.10.1227 |
0.317 |
|
| 1994 |
Kovats S, Drover S, Marshall WH, Freed D, Whiteley PE, Nepom GT, Blum JS. Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome. The Journal of Experimental Medicine. 179: 2017-22. PMID 8195723 DOI: 10.1084/jem.179.6.2017 |
0.324 |
|
| 1993 |
Miller G, Nepom GT, Reich MB, Thomas JW. Autoreactive T cells from a type I diabetic recognize multiple class II products. Human Immunology. 36: 219-26. PMID 8340230 DOI: 10.1016/0198-8859(93)90128-N |
0.332 |
|
| 1993 |
Sukiennicki TL, Shewey LM, Nepom GT. Locus- and allele-specific DNA-protein interactions in the HLA-DQB1 X box. Immunologic Research. 12: 317-29. PMID 8151156 DOI: 10.1007/Bf02935505 |
0.722 |
|
| 1991 |
Andersen LC, Beaty JS, Nettles JW, Seyfried CE, Nepom GT, Nepoom BS. Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes. The Journal of Experimental Medicine. 173: 181-92. PMID 1985121 DOI: 10.1084/JEM.173.1.181 |
0.329 |
|
| 1991 |
Nepom GT. Mutagenesis and expression of putative class II susceptibility genes: a "reverse immunogenetics" approach to analysis of HLA and disease. Autoimmunity. 7: 189-99. PMID 1716479 DOI: 10.3109/08916939008993391 |
0.35 |
|
| 1991 |
Mickelson EM, Masewicz SA, Nepom GT, Martin PJ, Hansen JA. Alloreactive T-cell clones identify multiple HLA-DQw3 variants. Human Immunology. 30: 32-40. PMID 1705927 DOI: 10.1016/0198-8859(91)90068-K |
0.304 |
|
| 1988 |
Seyfried CE, Mickelson E, Hansen JA, Nepom GT. A specific nucleotide sequence defines a functional T-cell recognition epitope shared by diverse HLA-DR specificities. Human Immunology. 21: 289-99. PMID 2453493 DOI: 10.1016/0198-8859(88)90037-7 |
0.31 |
|
| 1983 |
Torok-Storb B, Nepom GT, Nepom BS, Hansen JA. HLA-DR antigens on lymphoid cells differ from those on myeloid cells. Nature. 305: 541-3. PMID 6194439 DOI: 10.1038/305541A0 |
0.311 |
|
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