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Kristopher T. Kahle, Ph.D. - Publications

Affiliations: 
2007 Yale University, New Haven, CT 
Area:
Physiology Biology, Genetics
Website:
https://medicine.yale.edu/intranet/facultybydept/kristopher_kahle.profile
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123/273 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Singh AK, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, Zhao S, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T, Furey CG, Reeves BC, Smith H, Sousa AMM, ... ... Kahle KT, et al. A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus. Brain : a Journal of Neurology. PMID 38128548 DOI: 10.1093/brain/awad405  0.446
2023 Zhao S, Mekbib KY, van der Ent MA, Allington G, Prendergast A, Chau JE, Smith H, Shohfi J, Ocken J, Duran D, Furey CG, Hao LT, Duy PQ, Reeves BC, Zhang J, ... ... Kahle KT, et al. Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations. Nature Communications. 14: 7452. PMID 37978175 DOI: 10.1038/s41467-023-43062-z  0.46
2023 Khoshkhoo S, Wang Y, Chahine Y, Erson-Omay EZ, Robert SM, Kiziltug E, Damisah EC, Nelson-Williams C, Zhu G, Kong W, Huang AY, Stronge E, Phillips HW, Chhouk BH, Bizzotto S, ... ... Kahle KT, et al. Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy. Jama Neurology. PMID 37126322 DOI: 10.1001/jamaneurol.2023.0473  0.415
2023 Timberlake AT, McGee S, Allington G, Kiziltug E, Wolfe EM, Stiegler AL, Boggon TJ, Sanyoura M, Morrow M, Wenger TL, Fernandes EM, Caluseriu O, Persing JA, Jin SC, Lifton RP, ... Kahle KT, et al. De novo variants implicate chromatin modification, transcriptional regulation, and retinoic acid signaling in syndromic craniosynostosis. American Journal of Human Genetics. PMID 37086723 DOI: 10.1016/j.ajhg.2023.03.017  0.424
2023 Singh AK, Viviano S, Allington G, McGee S, Kiziltug E, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T, Furey CG, Reeves BC, Smith H, Ma S, Sousa AMM, Cherskov A, ... ... Kahle KT, et al. A novel -mutant BAFopathy implicates epigenetic dysregulation of neural progenitors in hydrocephalus. Medrxiv : the Preprint Server For Health Sciences. PMID 36993720 DOI: 10.1101/2023.03.19.23287455  0.418
2023 Zhao S, Mekbib KY, van der Ent MA, Allington G, Prendergast A, Chau JE, Smith H, Shohfi J, Ocken J, Duran D, Furey CG, Le HT, Duy PQ, Reeves BC, Zhang J, ... ... Kahle KT, et al. Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations. Biorxiv : the Preprint Server For Biology. PMID 36993588 DOI: 10.1101/2023.03.18.532837  0.434
2023 Kundishora AJ, Allington G, McGee S, Mekbib KY, Gainullin V, Timberlake AT, Nelson-Williams C, Kiziltug E, Smith H, Ocken J, Shohfi J, Allocco A, Duy PQ, Elsamadicy AA, Dong W, ... ... Kahle KT, et al. Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts. Nature Medicine. PMID 36879130 DOI: 10.1038/s41591-023-02238-2  0.435
2023 Robert SM, Reeves BC, Kiziltug E, Duy PQ, Karimy JK, Mansuri MS, Marlier A, Allington G, Greenberg ABW, DeSpenza T, Singh AK, Zeng X, Mekbib KY, Kundishora AJ, Nelson-Williams C, ... ... Kahle KT, et al. The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus. Cell. 186: 764-785.e21. PMID 36803604 DOI: 10.1016/j.cell.2023.01.017  0.592
2022 Timberlake AT, Kiziltug E, Jin SC, Nelson-Williams C, Loring E, Allocco A, Marlier A, Banka S, Stuart H, Passos-Buenos MR, Rosa R, Rogatto SR, Tonne E, Stiegler AL, Boggon TJ, ... ... Kahle KT, et al. De novo mutations in the BMP signaling pathway in lambdoid craniosynostosis. Human Genetics. PMID 35997807 DOI: 10.1007/s00439-022-02477-2  0.448
2022 Duy PQ, Timberlake AT, Lifton RP, Kahle KT. Molecular genetics of human developmental neurocranial anomalies: towards "precision surgery". Cerebral Cortex (New York, N.Y. : 1991). PMID 35739418 DOI: 10.1093/cercor/bhac249  0.427
2022 Küry S, Zhang J, Besnard T, Caro-Llopis A, Zeng X, Robert SM, Josiah SS, Kiziltug E, Denommé-Pichon AS, Cogné B, Kundishora AJ, Hao LT, Li H, Stevenson RE, Louie RJ, ... ... Kahle KT, et al. Rare pathogenic variants in WNK3 cause X-linked intellectual disability. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 35678782 DOI: 10.1016/j.gim.2022.05.009  0.786
2022 Wang J, Liu R, Hasan MN, Fischer S, Chen Y, Como M, Fiesler VM, Bhuiyan MIH, Dong S, Li E, Kahle KT, Zhang J, Deng X, Subramanya AR, Begum G, et al. Role of SPAK-NKCC1 signaling cascade in the choroid plexus blood-CSF barrier damage after stroke. Journal of Neuroinflammation. 19: 91. PMID 35413993 DOI: 10.1186/s12974-022-02456-4  0.495
2022 Duy PQ, Weise SC, Marini C, Li XJ, Liang D, Dahl PJ, Ma S, Spajic A, Dong W, Juusola J, Kiziltug E, Kundishora AJ, Koundal S, Pedram MZ, Torres-Fernández LA, ... ... Kahle KT, et al. Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus. Nature Neuroscience. PMID 35379995 DOI: 10.1038/s41593-022-01043-3  0.448
2022 Bhuiyan MIH, Young CB, Jahan I, Hasan MN, Fischer S, Meor Azlan NF, Liu M, Chattopadhyay A, Huang H, Kahle KT, Zhang J, Poloyac SM, Molyneaux BJ, Straub AC, Deng X, et al. NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice. Stroke. STROKEAHA121038351. PMID 35272484 DOI: 10.1161/STROKEAHA.121.038351  0.775
2021 Barak T, Ristori E, Ercan-Sencicek AG, Miyagishima DF, Nelson-Williams C, Dong W, Jin SC, Prendergast A, Armero W, Henegariu O, Erson-Omay EZ, Harmancı AS, Guy M, Gültekin B, Kilic D, ... ... Kahle KT, et al. PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans. Nature Medicine. 27: 2165-2175. PMID 34887573 DOI: 10.1038/s41591-021-01572-7  0.477
2021 Kundishora AJ, Peters ST, Pinard A, Duran D, Panchagnula S, Barak T, Miyagishima DF, Dong W, Smith H, Ocken J, Dunbar A, Nelson-Williams C, Haider S, Walker RL, Li B, ... ... Kahle KT, et al. DIAPH1 Variants in Non-East Asian Patients With Sporadic Moyamoya Disease. Jama Neurology. PMID 34125151 DOI: 10.1001/jamaneurol.2021.1681  0.42
2020 Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, Castonguay A, Lorenzo LÉ, Islam B, Brindle G, Bachand K, Hu J, Sularz A, Gaillard J, Choi J, ... ... Kahle KT, et al. Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia. Iscience. 23: 101552. PMID 33083721 DOI: 10.1016/J.Isci.2020.101552  0.518
2020 Jin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, ... ... Kahle KT, et al. Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus. Nature Medicine. PMID 33077954 DOI: 10.1038/s41591-020-1090-2  0.456
2020 Robert SM, Reeves BC, Alper SL, Zhang J, Kahle KT. New drugs on the horizon for cerebral edema: what's in the clinical development pipeline? Expert Opinion On Investigational Drugs. PMID 32815401 DOI: 10.1080/13543784.2020.1813715  0.516
2020 Hong CS, Vasquez JC, Kundishora AJ, Elsamadicy AA, Beckta JM, Sule A, Marks AM, Leelatian N, Huttner A, Bindra RS, DiLuna ML, Kahle KT, Erson-Omay EZ. Persistent mutation despite multimodal therapy in recurrent pediatric glioblastoma. Npj Genomic Medicine. 5: 23. PMID 32528726 DOI: 10.1038/S41525-020-0130-7  0.316
2020 Duy PQ, He M, He Z, Kahle KT. Preclinical insights into therapeutic targeting of KCC2 for disorders of neuronal hyperexcitability. Expert Opinion On Therapeutic Targets. PMID 32336175 DOI: 10.1080/14728222.2020.1762174  0.301
2020 Karimy JK, Reeves BC, Kahle KT. Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury. Expert Opinion On Therapeutic Targets. 1-9. PMID 32249624 DOI: 10.1080/14728222.2020.1752182  0.311
2020 Karimy JK, Reeves BC, Damisah E, Duy PQ, Antwi P, David W, Wang K, Schiff SJ, Limbrick DD, Alper SL, Warf BC, Nedergaard M, Simard JM, Kahle KT. Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets. Nature Reviews. Neurology. PMID 32152460 DOI: 10.1038/S41582-020-0321-Y  0.313
2020 Zhang J, Bhuiyan MIH, Zhang T, Karimy JK, Wu Z, Fiesler VM, Zhang J, Huang H, Hasan MN, Skrzypiec AE, Mucha M, Duran D, Huang W, Pawlak R, Foley LM, ... ... Kahle KT, et al. Modulation of brain cation-Cl cotransport via the SPAK kinase inhibitor ZT-1a. Nature Communications. 11: 78. PMID 31911626 DOI: 10.1038/S41467-019-13851-6  0.563
2019 Duy PQ, David WB, Kahle KT. Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation. Frontiers in Cellular Neuroscience. 13: 515. PMID 31803025 DOI: 10.3389/Fncel.2019.00515  0.356
2019 Fomchenko EI, Erson-Omay EZ, Kundishora AJ, Hong CS, Daniel AA, Allocco A, Duy PQ, Darbinyan A, Marks AM, DiLuna ML, Kahle KT, Huttner A. Genomic alterations underlying spinal metastases in pediatric H3K27M-mutant pineal parenchymal tumor of intermediate differentiation: case report. Journal of Neurosurgery. Pediatrics. 1-10. PMID 31653819 DOI: 10.3171/2019.8.Peds18664  0.309
2019 Allocco AA, Jin SC, Duy PQ, Furey CG, Zeng X, Dong W, Nelson-Williams C, Karimy JK, DeSpenza T, Hao LT, Reeves B, Haider S, Gunel M, Lifton RP, Kahle KT. Recessive Inheritance of Congenital Hydrocephalus With Other Structural Brain Abnormalities Caused by Compound Heterozygous Mutations in . Frontiers in Cellular Neuroscience. 13: 425. PMID 31616254 DOI: 10.3389/Fncel.2019.00425  0.55
2019 Watanabe M, Zhang J, Mansuri MS, Duan J, Karimy JK, Delpire E, Alper SL, Lifton RP, Fukuda A, Kahle KT. Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival. Science Signaling. 12. PMID 31615901 DOI: 10.1126/Scisignal.Aaw9315  0.658
2019 Pisella LI, Gaiarsa JL, Diabira D, Zhang J, Khalilov I, Duan J, Kahle KT, Medina I. Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology. Science Signaling. 12. PMID 31615899 DOI: 10.1126/Scisignal.Aay0300  0.529
2019 Lanni JS, Peal D, Ekstrom L, Chen H, Stanclift C, Bowen ME, Mercado A, Gamba G, Kahle KT, Harris MP. Integrated K+ channel and K+Cl- cotransporter function are required for the coordination of size and proportion during development. Developmental Biology. PMID 31472116 DOI: 10.1016/J.Ydbio.2019.08.016  0.369
2019 Jin SC, Furey CG, Zeng X, Allocco A, Nelson-Williams C, Dong W, Karimy JK, Wang K, Ma S, Delpire E, Kahle KT. SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus. Molecular Genetics & Genomic Medicine. e892. PMID 31393094 DOI: 10.1002/Mgg3.892  0.307
2019 Huang H, Song S, Banerjee S, Jiang T, Zhang J, Kahle KT, Sun D, Zhang Z. The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases. Aging and Disease. 10: 626-636. PMID 31165006 DOI: 10.14336/Ad.2018.0928  0.628
2019 Duy PQ, Furey CG, Kahle KT. Trim71/lin-41 Links an Ancient miRNA Pathway to Human Congenital Hydrocephalus. Trends in Molecular Medicine. PMID 30975633 DOI: 10.1016/J.Molmed.2019.03.004  0.307
2019 Zeng X, Hunt A, Jin SC, Duran D, Gaillard J, Kahle KT. EphrinB2-EphB4-RASA1 Signaling in Human Cerebrovascular Development and Disease. Trends in Molecular Medicine. PMID 30819650 DOI: 10.1016/J.Molmed.2019.01.009  0.354
2019 Phan D, Foster D, Jux B, Lake E, Constable T, Kolanus W, Slack F, Kahle KT. Trim71 Links an Ancient MicroRNA Pathway to Neural Stem Cell Development and Human Congenital Hydrocephalus Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_649  0.33
2019 Kundishora A, Zeng X, Duran D, Allocco AA, Choi J, Jin SC, Conine SB, Nelson-Williams C, Gaillard J, Furey CG, Timberlake AT, Mansuri M, Sorscher M, Klein J, Lu Q, ... ... Kahle KT, et al. Exome Sequencing Defines the Molecular Pathogenesis of Vein of Galen Malformation Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_341  0.538
2019 Allocco AA, Jin SC, Dong W, Zeng X, Conine SB, Furey CG, Date PP, Gaillard J, Nelson-Williams C, Dunbar A, DeSpenza T, Deniz E, Khokha MK, Lifton RP, Kahle KT. Exome Sequencing Implicates SWI/SNF Chromatin Remodeling Genes in Human Congenital Hydrocephalus Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_133  0.514
2018 Duran D, Zeng X, Jin SC, Choi J, Nelson-Williams C, Yatsula B, Gaillard J, Furey CG, Lu Q, Timberlake AT, Dong W, Sorscher MA, Loring E, Klein J, Allocco A, ... ... Kahle KT, et al. Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation. Neuron. PMID 30578106 DOI: 10.1016/J.Neuron.2018.11.041  0.637
2018 Furey CG, Zeng X, Dong W, Jin SC, Choi J, Timberlake AT, Dunbar AM, Allocco AA, Günel M, Lifton RP, Kahle KT. Human genetics and molecular mechanisms of congenital hydrocephalus. World Neurosurgery. PMID 30205212 DOI: 10.1016/J.Wneu.2018.09.018  0.457
2018 Furey CG, Choi J, Jin SC, Zeng X, Timberlake AT, Nelson-Williams C, Mansuri MS, Lu Q, Duran D, Panchagnula S, Allocco A, Karimy JK, Khanna A, Gaillard JR, DeSpenza T, ... ... Kahle KT, et al. De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus. Neuron. PMID 29983323 DOI: 10.1016/J.Neuron.2018.06.019  0.508
2018 Walcott BP, Winkler EA, Zhou S, Birk H, Guo D, Koch MJ, Stapleton CJ, Spiegelman D, Dionne-Laporte A, Dion PA, Kahle KT, Rouleau GA, Lawton MT. Identification of a rare pathway mutation in a non-syndromic human brain arteriovenous malformation via exome sequencing. Human Genome Variation. 5: 18001. PMID 29844917 DOI: 10.1038/Hgv.2018.1  0.357
2018 Duran D, Karschnia P, Gaillard JR, Karimy JK, Youngblood MW, DiLuna ML, Matouk CC, Aagaard-Kienitz B, Smith ER, Orbach DB, Rodesch G, Berenstein A, Gunel M, Kahle KT. Human genetics and molecular mechanisms of vein of Galen malformation. Journal of Neurosurgery. Pediatrics. 1-8. PMID 29350590 DOI: 10.3171/2017.9.Peds17365  0.339
2018 Furey CG, Jin SC, Timberlake AT, Choi J, Zeng X, Nelson-Williams C, Mansuri M, Lu Q, Duran D, Panchagnula S, Alloco A, Karimy JK, Gaillard J, Khanna A, Butler W, ... ... Kahle KT, et al. 125 De Novo Mutations in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus Neurosurgery. 65: 88-89. DOI: 10.1093/Neuros/Nyy303.125  0.495
2017 Heubl M, Zhang J, Pressey JC, Al Awabdh S, Renner M, Gomez-Castro F, Moutkine I, Eugène E, Russeau M, Kahle KT, Poncer JC, Lévi S. GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase. Nature Communications. 8: 1776. PMID 29176664 DOI: 10.1038/S41467-017-01749-0  0.582
2017 Timberlake AT, Furey CG, Choi J, Nelson-Williams C, Loring E, Galm A, Kahle KT, Steinbacher DM, Larysz D, Persing JA, Lifton RP. De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808027 DOI: 10.1073/Pnas.1709255114  0.523
2017 Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Stokum JA, Furey CG, Zhou X, Mansuri MS, Montejo J, Vera A, DiLuna ML, Delpire E, Alper SL, Gunel M, ... ... Kahle KT, et al. Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus. Nature Medicine. PMID 28692063 DOI: 10.1038/Nm.4361  0.553
2017 Zhang J, Karimy JK, Delpire E, Kahle KT. Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport. Expert Opinion On Therapeutic Targets. PMID 28679296 DOI: 10.1080/14728222.2017.1351949  0.611
2017 Glykys J, Dzhala V, Egawa K, Kahle KT, Delpire E, Staley K. Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential. Trends in Neurosciences. PMID 28431741 DOI: 10.1016/J.Tins.2017.03.006  0.346
2017 Shekarabi M, Zhang J, Khanna AR, Ellison DH, Delpire E, Kahle KT. WNK Kinase Signaling in Ion Homeostasis and Human Disease. Cell Metabolism. 25: 285-299. PMID 28178566 DOI: 10.1016/J.Cmet.2017.01.007  0.596
2017 Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Furey CG, Gerzanich V, Simard JM, Kahle KT. 166 TLR-4-Regulated Cerebrospinal Fluid Hypersecretion in Post-Hemorrhagic Hydrocephalus Neurosurgery. 64: 242-242. DOI: 10.1093/Neuros/Nyx417.166  0.538
2017 Furey CG, Choi J, Duran D, Timberlake AT, Zeng X, Nelson-Williams C, Khanna A, Iskandar B, Butler W, Heuer GG, Bayri Y, Sahin Y, Limbrick DD, Warf BC, Duncan CC, ... ... Kahle KT, et al. 102 Exome Sequencing Identifies Novel Molecular Determinants of Human Congenital Hydrocephalus Neurosurgery. 64: 220-220. DOI: 10.1093/Neuros/Nyx417.102  0.499
2016 Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ. Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover. Genes & Development. 30: 2684-2695. PMID 28087713 DOI: 10.1101/Gad.290122.116  0.544
2016 Duran D, Jin SC, DeSpenza T, Nelson-Williams C, Cogal AG, Abrash EW, Harris PC, Lieske JC, Shimshak SJ, Mane S, Bilguvar K, DiLuna ML, Günel M, Lifton RP, Kahle KT. Digenic mutations of human OCRL paralogs in Dent's disease type 2 associated with Chiari I malformation. Human Genome Variation. 3: 16042. PMID 28018608 DOI: 10.1038/Hgv.2016.42  0.523
2016 Zhang J, Deng X, Kahle KT. Leveraging unique structural characteristics of WNK kinases to achieve therapeutic inhibition. Science Signaling. 9: pe3. PMID 27811182 DOI: 10.1126/Scisignal.Aaj2227  0.594
2016 Karimy JK, Duran D, Hu JK, Gavankar C, Gaillard JR, Bayri Y, Rice H, DiLuna ML, Gerzanich V, Marc Simard J, Kahle KT. Cerebrospinal fluid hypersecretion in pediatric hydrocephalus. Neurosurgical Focus. 41: E10. PMID 27798982 DOI: 10.3171/2016.8.Focus16278  0.347
2016 Bhuiyan MI, Song S, Yuan H, Begum G, Kofler J, Kahle KT, Yang SS, Lin SH, Alper SL, Subramanya AR, Sun D. WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27798271 DOI: 10.1177/0271678X16675368  0.346
2016 Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, ... ... Kahle KT, et al. Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain. Scientific Reports. 6: 35986. PMID 27782176 DOI: 10.1038/Srep35986  0.756
2016 Kahle KT, Flores B, Bharucha-Goebel D, Zhang J, Donkervoort S, Hegde M, Hussain G, Duran D, Liang B, Sun D, Bönnemann CG, Delpire E. Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter. Science Signaling. 9: ra77. PMID 27485015 DOI: 10.1126/Scisignal.Aae0546  0.614
2016 Kahle KT, Khanna AR, Duan J, Staley KJ, Delpire E, Poduri A. The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 27130838 DOI: 10.1177/1073858416645087  0.344
2016 Kahle KT, Schmouth JF, Lavastre V, Latremoliere A, Zhang J, Andrews N, Omura T, Laganière J, Rochefort D, Hince P, Castonguay G, Gaudet R, Mapplebeck JC, Sotocinal SG, Duan J, et al. Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition. Science Signaling. 9: ra32. PMID 27025876 DOI: 10.1126/Scisignal.Aad0163  0.537
2016 Merner ND, Mercado A, Khanna AR, Hodgkinson A, Bruat V, Awadalla P, Gamba G, Rouleau GA, Kahle KT. Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia. Journal of Psychiatric Research. 77: 22-26. PMID 26955005 DOI: 10.1016/J.Jpsychires.2016.02.016  0.339
2016 Zhao H, Nepomuceno R, Gao X, Foley LM, Wang S, Begum G, Zhu W, Pigott VM, Falgoust LM, Kahle KT, Yang SS, Lin SH, Alper SL, Kevin Hitchens T, Hu S, et al. Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26861815 DOI: 10.1177/0271678X16631561  0.329
2015 Merner ND, Chandler MR, Bourassa C, Liang B, Khanna AR, Dion P, Rouleau GA, Kahle KT. Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia. Frontiers in Cellular Neuroscience. 9: 386. PMID 26528127 DOI: 10.3389/Fncel.2015.00386  0.322
2015 Kahle KT, Delpire E. Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target. Journal of Neurophysiology. jn.00865.2015. PMID 26510764 DOI: 10.1152/Jn.00865.2015  0.445
2015 Kahle KT, Kulkarni AV, Limbrick DD, Warf BC. Hydrocephalus in children. Lancet (London, England). PMID 26256071 DOI: 10.1016/S0140-6736(15)60694-8  0.305
2015 Adragna NC, Ravilla NB, Lauf PK, Begum G, Khanna AR, Sun D, Kahle KT. Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis. Frontiers in Cellular Neuroscience. 9: 255. PMID 26217182 DOI: 10.3389/Fncel.2015.00255  0.438
2015 Kahle KT, Khanna AR, Alper SL, Adragna NC, Lauf PK, Sun D, Delpire E. K-Cl cotransporters, cell volume homeostasis, and neurological disease. Trends in Molecular Medicine. 21: 513-23. PMID 26142773 DOI: 10.1016/J.Molmed.2015.05.008  0.434
2015 Friedel P, Kahle KT, Zhang J, Hertz N, Pisella LI, Buhler E, Schaller F, Duan J, Khanna AR, Bishop PN, Shokat KM, Medina I. WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons. Science Signaling. 8: ra65. PMID 26126716 DOI: 10.1126/Scisignal.Aaa0354  0.579
2015 Begum G, Yuan H, Kahle KT, Li L, Wang S, Shi Y, Shmukler BE, Yang SS, Lin SH, Alper SL, Sun D. Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke. Stroke; a Journal of Cerebral Circulation. 46: 1956-65. PMID 26069258 DOI: 10.1161/Strokeaha.115.008939  0.425
2015 Campbell SL, Robel S, Cuddapah VA, Robert S, Buckingham SC, Kahle KT, Sontheimer H. GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy. Glia. 63: 23-36. PMID 25066727 DOI: 10.1002/Glia.22730  0.319
2015 Kahle KT, VanHook AM. Science SignalingPodcast: 30 June 2015 Science Signaling. 8: pc16-pc16. DOI: 10.1126/Scisignal.Aac8012  0.315
2014 Alessi DR, Zhang J, Khanna A, Hochdörfer T, Shang Y, Kahle KT. The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters. Science Signaling. 7: re3. PMID 25028718 DOI: 10.1126/Scisignal.2005365  0.722
2014 Kahle KT, Merner ND, Friedel P, Silayeva L, Liang B, Khanna A, Shang Y, Lachance-Touchette P, Bourassa C, Levert A, Dion PA, Walcott B, Spiegelman D, Dionne-Laporte A, Hodgkinson A, et al. Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy. Embo Reports. 15: 766-74. PMID 24928908 DOI: 10.15252/Embr.201438840  0.369
2014 Kahle KT, Khanna A, Clapham DE, Woolf CJ. Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. Jama Neurology. 71: 640-5. PMID 24615367 DOI: 10.1001/Jamaneurol.2014.21  0.498
2014 Medina I, Friedel P, Rivera C, Kahle KT, Kourdougli N, Uvarov P, Pellegrino C. Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2. Frontiers in Cellular Neuroscience. 8: 27. PMID 24567703 DOI: 10.3389/Fncel.2014.00027  0.398
2014 Zhu W, Begum G, Pointer K, Clark PA, Yang SS, Lin SH, Kahle KT, Kuo JS, Sun D. WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration. Molecular Cancer. 13: 31. PMID 24555568 DOI: 10.1186/1476-4598-13-31  0.417
2014 Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. Local impermeant anions establish the neuronal chloride concentration. Science (New York, N.Y.). 343: 670-5. PMID 24503855 DOI: 10.1126/Science.1245423  0.338
2014 Sun D, Kahle KT. Dysregulation of diverse ion transport pathways controlling cell volume homoestasis contribute to neuroglial cell injury following ischemic stroke. Translational Stroke Research. 5: 1-2. PMID 24464825 DOI: 10.1007/S12975-014-0324-3  0.341
2014 de Los Heros P, Alessi DR, Gourlay R, Campbell DG, Deak M, Macartney TJ, Kahle KT, Zhang J. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. The Biochemical Journal. 458: 559-73. PMID 24393035 DOI: 10.1042/Bj20131478  0.711
2014 Khanna A, Walcott BP, Kahle KT, Simard JM. Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans. Neurosurgical Focus. 36: E11. PMID 24380477 DOI: 10.3171/2013.10.Focus13404  0.311
2014 Khanna A, Kahle KT, Walcott BP, Gerzanich V, Simard JM. Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema. Translational Stroke Research. 5: 3-16. PMID 24323726 DOI: 10.1007/S12975-013-0307-9  0.341
2014 Lee HK, Ahmed MM, King KC, Miranpuri GS, Kahle KT, Resnick DK, Sun D. Persistent phosphorylation of NKCC1 and WNK1 in the epicenter of the spinal cord following contusion injury. The Spine Journal : Official Journal of the North American Spine Society. 14: 777-81. PMID 24239489 DOI: 10.1016/J.Spinee.2013.06.100  0.328
2014 Kahle KT, Gao G, Zhang J, Latremoliere A, Andrews N, Shang Y, Alessi D, Woolf C, Elledge S, Clapham D. Ronald R. Tasker Young Investigator Award 165 Promoting Endogenous GABAergic Analgesia via Kinase Modulation of Neuronal Ion Plasticity Neurosurgery. 61: 214. DOI: 10.1227/01.Neu.0000452440.75411.82  0.684
2013 Kahle KT, Deeb TZ, Puskarjov M, Silayeva L, Liang B, Kaila K, Moss SJ. Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2. Trends in Neurosciences. 36: 726-37. PMID 24139641 DOI: 10.1016/J.Tins.2013.08.006  0.44
2013 Khanna A, Walcott BP, Kahle KT. Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport. Frontiers in Neurology. 4: 78. PMID 23805124 DOI: 10.3389/Fneur.2013.00078  0.304
2013 Arroyo JP, Kahle KT, Gamba G. The SLC12 family of electroneutral cation-coupled chloride cotransporters. Molecular Aspects of Medicine. 34: 288-98. PMID 23506871 DOI: 10.1016/J.Mam.2012.05.002  0.34
2013 Li J, Zhu S, Kozono D, Futulan D, Gonda D, Kushwaha D, Kahle K, Elledge S, Chen CC. Abstract 4366: ShRNA-based cellular proliferation signaling analysis revealed DRD2 as a novel therapeutic target for glioblastoma. Cancer Research. 73: 4366-4366. DOI: 10.1158/1538-7445.Am2013-4366  0.522
2012 Algharabil J, Kintner DB, Wang Q, Begum G, Clark PA, Yang SS, Lin SH, Kahle KT, Kuo JS, Sun D. Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 30: 33-48. PMID 22759954 DOI: 10.1159/000339047  0.374
2012 Ben-Ari Y, Khalilov I, Kahle KT, Cherubini E. The GABA excitatory/inhibitory shift in brain maturation and neurological disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 18: 467-86. PMID 22547529 DOI: 10.1177/1073858412438697  0.335
2012 Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science (New York, N.Y.). 335: 348-53. PMID 22157079 DOI: 10.1126/Science.1212728  0.694
2012 Walcott BP, Kahle KT, Simard JM. Novel treatment targets for cerebral edema. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 65-72. PMID 22125096 DOI: 10.1007/S13311-011-0087-4  0.341
2012 Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, et al. Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis Cancer Research. 72: 3091-3091. DOI: 10.1158/1538-7445.Am2012-3091  0.696
2011 Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP. WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. The Journal of Biological Chemistry. 286: 30171-80. PMID 21733846 DOI: 10.1074/Jbc.M111.222893  0.611
2011 Kahle KT, Walcott BP, Staley KJ. Resolution of headache and papilledema in idiopathic intracranial hypertension associated with inhibition of Na+-K+-2Cl- cotransport. Journal of Child Neurology. 26: 205-8. PMID 21285039 DOI: 10.1177/0883073810391264  0.311
2010 Wang Y, Suo H, Zheng Y, Liu K, Zhuang C, Kahle KT, Ma H, Yan X. The soybean root-specific protein kinase GmWNK1 regulates stress-responsive ABA signaling on the root system architecture. The Plant Journal : For Cell and Molecular Biology. 64: 230-42. PMID 20735771 DOI: 10.1111/J.1365-313X.2010.04320.X  0.379
2010 Kahle KT, Rinehart J, Lifton RP. Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases. Biochimica Et Biophysica Acta. 1802: 1150-8. PMID 20637866 DOI: 10.1016/J.Bbadis.2010.07.009  0.628
2010 Kahle KT, Kozono D, Kimberly NG, Hsieh G, Zinn PO, Nitta M, Chen CC. Functional genomics to explore cancer cell vulnerabilities Neurosurgical Focus. 28: E5.1-E5.7. PMID 20043720 DOI: 10.3171/2009.10.Focus09212  0.301
2010 Simard JM, Kahle KT, Gerzanich V. Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4. Journal of Neurosurgery. 113: 622-9. PMID 20035575 DOI: 10.3171/2009.11.Jns081052  0.367
2009 Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda, Md.). 24: 257-65. PMID 19675357 DOI: 10.1152/Physiol.00015.2009  0.348
2009 San-Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G. Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 4384-9. PMID 19240212 DOI: 10.1073/Pnas.0813238106  0.704
2009 Kahle KT, Wilson FH, Lifton RP. The Syndrome of Hypertension and Hyperkalemia (Pseudohypoaldosteronism Type II): WNK Kinases Regulate the Balance Between Renal Salt Reabsorption and Potassium Secretion Genetic Diseases of the Kidney. 313-329. DOI: 10.1016/B978-0-12-449851-8.00019-X  0.729
2008 Kahle KT, Staley KJ, Nahed BV, Gamba G, Hebert SC, Lifton RP, Mount DB. Roles of the cation-chloride cotransporters in neurological disease. Nature Clinical Practice. Neurology. 4: 490-503. PMID 18769373 DOI: 10.1038/Ncpneuro0883  0.585
2008 Kahle KT, Staley KJ. The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures. Neurosurgical Focus. 25: E22. PMID 18759624 DOI: 10.3171/Foc/2008/25/9/E22  0.343
2008 Ponce-Coria J, San-Cristobal P, Kahle KT, Vazquez N, Pacheco-Alvarez D, de Los Heros P, Juárez P, Muñoz E, Michel G, Bobadilla NA, Gimenez I, Lifton RP, Hebert SC, Gamba G. Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 8458-63. PMID 18550832 DOI: 10.1073/Pnas.0802966105  0.625
2008 Kahle KT, Staley K. Altered neuronal chloride homeostasis and excitatory GABAergic signaling in human temporal lobe epilepsy. Epilepsy Currents / American Epilepsy Society. 8: 51-3. PMID 18330470 DOI: 10.1111/J.1535-7511.2008.00235.X  0.373
2008 Kahle KT, Rinehart J, Giebisch G, Gamba G, Hebert SC, Lifton RP. A novel protein kinase signaling pathway essential for blood pressure regulation in humans. Trends in Endocrinology and Metabolism: Tem. 19: 91-5. PMID 18280177 DOI: 10.1016/J.Tem.2008.01.001  0.601
2008 Kahle KT, Ring AM, Lifton RP. Molecular physiology of the WNK kinases. Annual Review of Physiology. 70: 329-55. PMID 17961084 DOI: 10.1146/Annurev.Physiol.70.113006.100651  0.612
2008 Kahle KT, Ring AM, Lifton RP. Molecular physiology of the WNK kinases Annual Review of Physiology. 70: 329-355. DOI: 10.1146/annurev.physiol.70.113006.100651  0.459
2007 Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP. An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 4025-9. PMID 17360471 DOI: 10.1073/Pnas.0611728104  0.755
2007 Ring AM, Cheng SX, Leng Q, Kahle KT, Rinehart J, Lalioti MD, Volkman HM, Wilson FH, Hebert SC, Lifton RP. WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 4020-4. PMID 17360470 DOI: 10.1073/Pnas.0611727104  0.776
2006 Kahle KT, Rinehart J, Ring A, Gimenez I, Gamba G, Hebert SC, Lifton RP. WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda, Md.). 21: 326-35. PMID 16990453 DOI: 10.1152/Physiol.00015.2006  0.597
2006 Lalioti MD, Zhang J, Volkman HM, Kahle KT, Hoffmann KE, Toka HR, Nelson-Williams C, Ellison DH, Flavell R, Booth CJ, Lu Y, Geller DS, Lifton RP. Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nature Genetics. 38: 1124-32. PMID 16964266 DOI: 10.1038/Ng1877  0.66
2006 de Los Heros P, Kahle KT, Rinehart J, Bobadilla NA, Vázquez N, San Cristobal P, Mount DB, Lifton RP, Hebert SC, Gamba G. WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 1976-81. PMID 16446421 DOI: 10.1073/Pnas.0510947103  0.628
2006 Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC. WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). The Journal of Physiology. 571: 275-86. PMID 16357011 DOI: 10.1113/Jphysiol.2005.102202  0.785
2005 Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP. WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 102: 16777-82. PMID 16275913 DOI: 10.1073/Pnas.0508303102  0.784
2005 Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP. WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability. Proceedings of the National Academy of Sciences of the United States of America. 102: 16783-8. PMID 16275911 DOI: 10.1073/Pnas.0508307102  0.602
2005 Kahle KT, Wilson FH, Lifton RP. Regulation of diverse ion transport pathways by WNK4 kinase: A novel molecular switch Trends in Endocrinology and Metabolism. 16: 98-103. PMID 15808806 DOI: 10.1016/J.Tem.2005.02.012  0.785
2004 Kahle KT, MacGregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP. Paracellular Cl- permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension Proceedings of the National Academy of Sciences of the United States of America. 101: 14877-14882. PMID 15465913 DOI: 10.1073/Pnas.0406172101  0.777
2004 Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP. WNK kinases: molecular regulators of integrated epithelial ion transport. Current Opinion in Nephrology and Hypertension. 13: 557-62. PMID 15300163 DOI: 10.1097/00041552-200409000-00012  0.76
2004 Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP. WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia Proceedings of the National Academy of Sciences of the United States of America. 101: 2064-2069. PMID 14769928 DOI: 10.1073/Pnas.0308434100  0.78
2003 Kahle KT, Wilson FH, Leng Q, Lalioti MD, O'Connell AD, Dong K, Rapson AK, MacGregor GG, Giebisch G, Hebert SC, Lifton RP. WNK4 regulates the balance between renal NaCl reabsorption and K + secretion Nature Genetics. 35: 372-376. PMID 14608358 DOI: 10.1038/Ng1271  0.773
2003 Choate KA, Kahle KT, Wilson FH, Nelson-Williams C, Lifton RP. WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl--transporting epithelia Proceedings of the National Academy of Sciences of the United States of America. 100: 663-668. PMID 12522152 DOI: 10.1073/Pnas.242728499  0.803
2003 Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP. Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4 Proceedings of the National Academy of Sciences of the United States of America. 100: 680-684. PMID 12515852 DOI: 10.1073/Pnas.242735399  0.783
Low-probability matches (unlikely to be authored by this person)
2010 Eichler AF, Kahle KT, Wang DL, Joshi VA, Willers H, Engelman JA, Lynch TJ, Sequist LV. EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer. Neuro-Oncology. 12: 1193-9. PMID 20627894 DOI: 10.1200/Jco.2010.28.15_Suppl.7542  0.299
2010 Hasbargen T, Ahmed MM, Miranpuri G, Li L, Kahle KT, Resnick D, Sun D. Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury. Annals of the New York Academy of Sciences. 1198: 168-72. PMID 20536931 DOI: 10.1111/J.1749-6632.2010.05462.X  0.298
2014 Puskarjov M, Kahle KT, Ruusuvuori E, Kaila K. Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures. Epilepsia. 55: 806-18. PMID 24802699 DOI: 10.1111/Epi.12620  0.297
2018 Marks AM, Bindra RS, DiLuna ML, Huttner A, Jairam V, Kahle KT, Kieran MW. Response to the BRAF/MEK inhibitors dabrafenib/trametinib in an adolescent with a BRAF V600E mutated anaplastic ganglioglioma intolerant to vemurafenib. Pediatric Blood & Cancer. PMID 29380516 DOI: 10.1002/Pbc.26969  0.292
2012 Walcott BP, Edlow BL, Xia Z, Kahle KT, Nahed BV, Schmahmann JD. Steroid responsive A3243G mutation MELAS: clinical and radiographic evidence for regional hyperperfusion leading to neuronal loss. The Neurologist. 18: 159-70. PMID 22549360 DOI: 10.1097/Nrl.0B013E318247Bcd8  0.291
2010 Dzhala VI, Kuchibhotla KV, Glykys JC, Kahle KT, Swiercz WB, Feng G, Kuner T, Augustine GJ, Bacskai BJ, Staley KJ. Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11745-61. PMID 20810895 DOI: 10.1523/Jneurosci.1769-10.2010  0.281
2013 Ryu JH, Walcott BP, Kahle KT, Sheth SA, Peterson RT, Nahed BV, Coumans JV, Simard JM. Induced and sustained hypernatremia for the prevention and treatment of cerebral edema following brain injury. Neurocritical Care. 19: 222-31. PMID 23468135 DOI: 10.1007/S12028-013-9824-3  0.281
2019 Lalioti ME, Kaplani K, Lokka G, Georgomanolis T, Kyrousi C, Dong W, Dunbar A, Parlapani E, Damianidou E, Spassky N, Kahle KT, Papantonis A, Lygerou Z, Taraviras S. GemC1 is a critical switch for neural stem cell generation in the postnatal brain. Glia. PMID 31328313 DOI: 10.1002/Glia.23690  0.281
2019 Date P, Ackermann P, Furey C, Fink IB, Jonas S, Khokha MK, Kahle KT, Deniz E. Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus. Scientific Reports. 9: 6196. PMID 30996265 DOI: 10.1038/S41598-019-42549-4  0.276
2011 Maa EH, Kahle KT, Walcott BP, Spitz MC, Staley KJ. Diuretics and epilepsy: will the past and present meet? Epilepsia. 52: 1559-69. PMID 21838793 DOI: 10.1111/J.1528-1167.2011.03203.X  0.276
2009 Kahle KT, Barnett SM, Sassower KC, Staley KJ. Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1. Journal of Child Neurology. 24: 572-6. PMID 19406757 DOI: 10.1177/0883073809333526  0.275
2016 Leasure A, Kimberly WT, Sansing LH, Kahle KT, Kronenberg G, Kunte H, Simard JM, Sheth KN. Treatment of Edema Associated With Intracerebral Hemorrhage. Current Treatment Options in Neurology. 18: 9. PMID 26874842 DOI: 10.1007/S11940-015-0392-Z  0.271
2010 Kahle KT, Staley KJ. A treatment paradigm for neonatal seizures based on the ontogeny of neuronal chloride/cation cotransporter expression in the human cortex Epilepsia. 51: 89. DOI: 10.1111/J.1528-1167.2010.02875.X  0.27
2015 Karimy JK, Kahle KT, Kurland DB, Yu E, Gerzanich V, Simard JM. A novel method to study cerebrospinal fluid dynamics in rats. Journal of Neuroscience Methods. 241: 78-84. PMID 25554415 DOI: 10.1016/J.Jneumeth.2014.12.015  0.27
2013 Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Berry G, Jensen FE. Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures. Plos One. 8: e57148. PMID 23536761 DOI: 10.1371/Journal.Pone.0057148  0.27
2013 Kahle KT, Walcott BP, Simard JM. Continuous hyperosmolar therapy for traumatic brain injury-associated cerebral edema: as good as it gets, or an iatrogenic secondary insult? Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 20: 30-1. PMID 23200533 DOI: 10.1016/J.Jocn.2012.10.004  0.267
2018 Hong C, Kundishora A, Erson Omay EZ, Huttner A, Marks A, Diluna M, Kahle K. PDTM-35. GENETIC ALTERATIONS DRIVING SPINAL INTRAMEDULLARY METASTASES OF A HISTONE-MUTATED DIFFUSE MIDLINE PINEAL GLIOMA Neuro-Oncology. 20: vi211-vi211. DOI: 10.1093/Neuonc/Noy148.875  0.267
2015 Adragna NC, Ravilla NB, Lauf PK, Begum G, Khanna AR, Sun D, Kahle KT. Regulated phosphorylation of the K-CL cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis Frontiers in Cellular Neuroscience. 9. DOI: 10.3389/fncel.2015.00255  0.266
2011 Schanker BD, Walcott BP, Nahed BV, Kahle KT, Li YM, Coumans JV. Familial Chiari malformation: case series. Neurosurgical Focus. 31: E1. PMID 21882906 DOI: 10.3171/2011.6.Focus11104  0.264
2019 Hong C, Kundishora A, Fomchenko E, Huttner A, Erson-Omay Z, Marks A, Diluna M, Kahle K. HGG-01. ACQUISITION OF A HYPERMUTATOR PHENOTYPE UNDERLYING DISTANT SPINAL INTRAMEDULLARY SPREAD IN HISTONE-MUTATED DIFFUSE MIDLINE GLIOMA Neuro-Oncology. 21: ii86-ii86. DOI: 10.1093/Neuonc/Noz036.095  0.264
2001 Abe MK, Kahle KT, Saelzler MP, Orth K, Dixon JE, Rosner MR. ERK7 is an autoactivated member of the MAPK family. The Journal of Biological Chemistry. 276: 21272-9. PMID 11287416 DOI: 10.1074/Jbc.M100026200  0.263
2012 Barnard ZR, Walcott BP, Kahle KT, Nahed BV, Coumans JV. Hyponatremia associated with Ipilimumab-induced hypophysitis. Medical Oncology (Northwood, London, England). 29: 374-7. PMID 21264545 DOI: 10.1007/S12032-010-9794-7  0.263
2014 Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. Response to comments on "Local impermeant anions establish the neuronal chloride concentration". Science (New York, N.Y.). 345: 1130. PMID 25190789 DOI: 10.1126/Science.1253146  0.262
2019 Hong CS, Kundishora AJ, Kahle KT, Diluna ML. Teaching NeuroImages: Unilateral focal segmental hyperhidrosis from spinal tumor progression. Neurology. 93: e729-e730. PMID 31405944 DOI: 10.1212/Wnl.0000000000007950  0.261
2013 Khanna A, Venteicher AS, Walcott BP, Kahle KT, Mordes DA, William CM, Ghogawala Z, Ogilvy CS. Glioblastoma mimicking an arteriovenous malformation. Frontiers in Neurology. 4: 144. PMID 24137154 DOI: 10.3389/Fneur.2013.00144  0.26
2017 Gaillard J, Klein J, Duran D, Storey A, Scott RM, Kahle K, Smith ER. Incidence, clinical features, and treatment of familial moyamoya in pediatric patients: a single-institution series. Journal of Neurosurgery. Pediatrics. 1-7. PMID 28291427 DOI: 10.3171/2016.12.Peds16468  0.256
2011 Walcott BP, Coumans JV, Mian MK, Nahed BV, Kahle KT. Interfacility helicopter ambulance transport of neurosurgical patients: observations, utilization, and outcomes from a quaternary level care hospital. Plos One. 6: e26216. PMID 22022572 DOI: 10.1371/Journal.Pone.0026216  0.254
2017 Vasquez JC, Huttner A, Zhang L, Marks A, Chan A, Baehring JM, Kahle KT, Dhodapkar KM. SOX2 immunity and tissue resident memory in children and young adults with glioma. Journal of Neuro-Oncology. PMID 28620836 DOI: 10.1007/S11060-017-2515-8  0.252
2017 Vasquez J, Huttner A, Zhang L, Marks A, Chan A, Baehring JM, Kahle K, Dhodapkar KM. SOX2 as a target for immunotherapy of pediatric gliomas. Journal of Clinical Oncology. 35: e22012-e22012. DOI: 10.1200/Jco.2017.35.15_Suppl.E22012  0.25
2017 Duran D, Hadzipasic M, Kahle KT. Mystery Case: Acute hydrocephalus caused by radiographically occult fourth ventricular outlet obstruction. Neurology. 88: e36-e37. PMID 28138085 DOI: 10.1212/Wnl.0000000000003555  0.247
2018 Panchagnula S, Sularz AK, Kahle KT. Familial Trigeminal Neuralgia Cases Implicate Genetic Factors in Disease Pathogenesis. Jama Neurology. PMID 30398541 DOI: 10.1001/Jamaneurol.2018.3322  0.246
2002 Abe MK, Saelzler MP, Espinosa R, Kahle KT, Hershenson MB, Le Beau MM, Rosner MR. ERK8, a new member of the mitogen-activated protein kinase family. The Journal of Biological Chemistry. 277: 16733-43. PMID 11875070 DOI: 10.1074/Jbc.M112483200  0.245
2012 Stapleton CJ, Walcott BP, Kahle KT, Codd PJ, Nahed BV, Chen L, Robison NJ, Delalle I, Goumnerova LC, Jackson EM. Diffuse central neurocytoma with craniospinal dissemination. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 163-6. PMID 22088950 DOI: 10.1016/J.Jocn.2011.07.016  0.245
2010 Naunheim MR, Nahed BV, Walcott BP, Kahle KT, Soupir CP, Cahill DP, Borges LF. Diagnosis of acute lymphoblastic leukemia from intracerebral hemorrhage and blast crisis. A case report and review of the literature. Clinical Neurology and Neurosurgery. 112: 575-7. PMID 20493628 DOI: 10.1016/J.Clineuro.2010.04.001  0.245
2009 Nahed BV, Ferreira M, Naunheim MR, Kahle KT, Proctor MR, Smith ER. Intracranial vasospasm with subsequent stroke after traumatic subarachnoid hemorrhage in a 22-month-old child. Journal of Neurosurgery. Pediatrics. 3: 311-5. PMID 19338410 DOI: 10.3171/2008.12.Peds08206  0.244
2011 Simard JM, Sahuquillo J, Sheth KN, Kahle KT, Walcott BP. Managing malignant cerebral infarction. Current Treatment Options in Neurology. 13: 217-29. PMID 21190097 DOI: 10.1007/S11940-010-0110-9  0.244
2021 Omer S, Jin SC, Koumangoye R, Robert SM, Duran D, Nelson-Williams C, Huttner A, DiLuna M, Kahle KT, Delpire E. Protein kinase D1 variant associated with human epilepsy and peripheral nerve hypermyelination. Clinical Genetics. PMID 33904160 DOI: 10.1111/cge.13973  0.243
2011 Nahed BV, Ferreira M, Babu MA, Terry AR, Walcott BP, Kahle KT, Smith ER. Dural scalp and intracranial hemangiomas causing hydrocephalus and venous sinus thrombosis in an infant. Journal of Child Neurology. 26: 777-81. PMID 21325128 DOI: 10.1177/0883073810390694  0.242
2011 Kahle KT, Walcott BP, Nahed BV, Barnard ZR, Lo EH, Buonanno FS, Venna N, Ning M. Cerebral edema and a transtentorial brain herniation syndrome associated with pandemic swine influenza A (H1N1) virus infection. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 1245-8. PMID 21742505 DOI: 10.1016/J.Jocn.2011.01.014  0.242
2011 Kesari S, Advani SJ, Lawson JD, Kahle KT, Ng K, Carter B, Chen CC. DNA damage response and repair: insights into strategies for radiation sensitization of gliomas. Future Oncology (London, England). 7: 1335-46. PMID 22044206 DOI: 10.2217/Fon.11.111  0.241
2018 Coletti AM, Singh D, Kumar S, Shafin TN, Briody PJ, Babbitt BF, Pan D, Norton ES, Brown EC, Kahle KT, Del Bigio MR, Conover JC. Characterization of the ventricular-subventricular stem cell niche during human brain development. Development (Cambridge, England). PMID 30237244 DOI: 10.1242/Dev.170100  0.241
2015 Ang JW, Khanna A, Walcott BP, Kahle KT, Eskandar EN. Central nervous system lymphoma presenting as trigeminal neuralgia: A diagnostic challenge. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 22: 1188-90. PMID 25865026 DOI: 10.1016/J.Jocn.2015.01.018  0.241
2016 Delpire E, Kahle KT. The KCC3 cotransporter as a therapeutic target for peripheral neuropathy. Expert Opinion On Therapeutic Targets. PMID 28019725 DOI: 10.1080/14728222.2017.1275569  0.24
2012 Walcott BP, Nahed BV, Kahle KT, Sekhar LN, Ferreira MJ. Cerebrovascular bypass and aneurysm trapping for the treatment of an A2-segment anterior cerebral artery pseudoaneurysm and herniation through a skull base defect following trauma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 149-51. PMID 22051032 DOI: 10.1016/J.Jocn.2011.05.017  0.239
2012 Walcott BP, Nahed BV, Sarpong Y, Kahle KT, Sekhar LN, Ferreira MJ. Incidence of cerebrospinal fluid leak following petrosectomy and analysis of avoidance techniques. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 92-4. PMID 22104349 DOI: 10.1016/J.Jocn.2011.08.001  0.238
2013 Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Kahle K, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174  0.238
2011 Walcott BP, Cvetanovich GL, Barnard ZR, Nahed BV, Kahle KT, Curry WT. Surgical treatment and outcomes of metastatic breast cancer to the spine. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 1336-9. PMID 21782449 DOI: 10.1016/J.Jocn.2011.02.020  0.238
2019 Hong CS, Camara-Quintana J, Kundishora AJ, Diluna ML, Kahle KT. Teaching NeuroImages: Spinal subdural hematoma in pediatric nonaccidental trauma. Neurology. 93: e522-e523. PMID 31358679 DOI: 10.1212/Wnl.0000000000007869  0.238
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Kahle KT, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.237
2012 Walcott BP, Nahed BV, Kahle KT, Duhaime AC, Sharma N, Eskandar EN. Deep brain stimulation for medically refractory life-threatening status dystonicus in children. Journal of Neurosurgery. Pediatrics. 9: 99-102. PMID 22208329 DOI: 10.3171/2011.10.Peds11360  0.236
2011 Walcott BP, Coumans JV, Kahle KT. Diagnostic pitfalls in spine surgery: masqueraders of surgical spine disease. Neurosurgical Focus. 31: E1. PMID 21961853 DOI: 10.3171/2011.7.Focus11114  0.236
2014 Walcott BP, Miller JC, Kwon CS, Sheth SA, Hiller M, Cronin CA, Schwamm LH, Simard JM, Kahle KT, Kimberly WT, Sheth KN. Outcomes in severe middle cerebral artery ischemic stroke. Neurocritical Care. 21: 20-6. PMID 23839704 DOI: 10.1007/S12028-013-9838-X  0.235
2018 Chesler D, Bram R, Antwi P, Timberlake AT, DiLuna ML, Kahle KT. Non-syndromic single-suture craniosynostosis in triplets. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 29460062 DOI: 10.1007/S00381-018-3754-5  0.235
2017 Duran D, Messina RD, Beslow LA, Montejo JD, Karimy JK, Gavankar Furey C, Sheridan AD, Sze G, Yarman Y, DiLuna ML, Kahle KT. Malignant Cerebellar Edema Subsequent to Accidental Prescription Opioid Intoxication in Children. Frontiers in Neurology. 8: 362. PMID 28790973 DOI: 10.3389/Fneur.2017.00362  0.234
2018 Montejo JD, Camara-Quintana JQ, Duran D, Rockefeller JM, Conine SB, Blaise AM, Kahle KT, DiLuna ML. Tubular approach to minimally invasive microdiscectomy for pediatric lumbar disc herniation. Journal of Neurosurgery. Pediatrics. 1-7. PMID 29473813 DOI: 10.3171/2017.11.Peds17293  0.234
2018 Penn DL, Lanpher AB, Klein JM, Kozakewich HPW, Kahle KT, Smith ER, Orbach DB. Multimodal treatment approach in a patient with multiple intracranial myxomatous aneurysms. Journal of Neurosurgery. Pediatrics. 1-7. PMID 29303459 DOI: 10.3171/2017.9.Peds17288  0.231
2016 Lucchesi KM, Grant R, Kahle KT, Marks AM, DiLuna ML. Primary spinal myxopapillary ependymoma in the pediatric population: a study from the Surveillance, Epidemiology, and End Results (SEER) database. Journal of Neuro-Oncology. PMID 27423644 DOI: 10.1007/S11060-016-2218-6  0.231
2012 Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, et al. 112 Genfome-wide shRNA Screening Defines the SUMO-activating Enzyme (SAE1/2) as a Novel Therapeutic Target for Tumors Driven by c-Myc Oncogenesis. Neurosurgery. 71: E547. PMID 28175742 DOI: 10.1227/01.Neu.0000417701.96799.49  0.23
2012 Walcott BP, Nahed BV, Mohyeldin A, Coumans JV, Kahle KT, Ferreira MJ. Chordoma: current concepts, management, and future directions. The Lancet. Oncology. 13: e69-76. PMID 22300861 DOI: 10.1016/S1470-2045(11)70337-0  0.228
2018 Subramanian HE, Mahajan A, Sommaruga S, Falcone GJ, Kahle KT, Matouk CC. The subjective experience of patients undergoing shunt surgery for idiopathic normal pressure hydrocephalus. World Neurosurgery. PMID 29981467 DOI: 10.1016/J.Wneu.2018.06.209  0.227
2011 Coumans JV, Walcott BP, Redjal N, Kahle KT, Nahed BV. En bloc excision of a dermal sinus tract. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 554-8. PMID 21316971 DOI: 10.1016/J.Jocn.2010.11.008  0.226
2020 Elsamadicy AA, Koo AB, Lee V, David WB, Zogg CK, Kundishora AJ, Hong CS, DeSpenza T, Reeves BC, DiLuna M, Kahle KT. Risk Factors for Post Traumatic Hydrocephalus following Pediatric Traumatic Brain Injury in the Emergency Department Setting. World Neurosurgery. PMID 32389871 DOI: 10.1016/J.Wneu.2020.04.216  0.226
2011 Walcott BP, Nahed BV, Redjal N, Stein TD, Kahle KT, Coumans JV. Pathological mechanism of lumbar disc herniation resulting in neurogenic muscle hypertrophy. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 1682-4. PMID 21985744 DOI: 10.1016/J.Jocn.2011.03.033  0.225
2013 Codd PJ, Venteicher AS, Agarwalla PK, Kahle KT, Jho DH. Endoscopic burr hole evacuation of an acute subdural hematoma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 20: 1751-3. PMID 23962631 DOI: 10.1016/J.Jocn.2013.02.019  0.224
2011 Walcott BP, Pisapia JM, Nahed BV, Kahle KT, Ogilvy CS. Early experience with flow diverting endoluminal stents for the treatment of intracranial aneurysms. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 891-4. PMID 21571535 DOI: 10.1016/J.Jocn.2011.01.002  0.224
2005 Nahed BV, DiLuna ML, Morgan T, Ocal E, Hawkins AA, Ozduman K, Kahle KT, Chamberlain A, Amar AP, Gunel M. Hypertension, age, and location predict rupture of small intracranial aneurysms. Neurosurgery. 57: 676-83; discussion 6. PMID 16239879 DOI: 10.1227/01.Neu.0000175549.96530.59  0.223
2011 Walcott BP, Kuklina EV, Nahed BV, George MG, Kahle KT, Simard JM, Asaad WF, Coumans JV. Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals. Plos One. 6: e29193. PMID 22195021 DOI: 10.1371/Journal.Pone.0029193  0.221
2020 Elsamadicy AA, Koo AB, Lee M, David WB, Kundishora AJ, Freedman IG, Zogg CK, Hong CS, DeSpenza T, Sarkozy M, Kahle KT, DiLuna M. Risk factors portending extended length of stay following suboccipital decompression for adult Chiari I malformation. World Neurosurgery. PMID 32147550 DOI: 10.1016/J.Wneu.2020.02.158  0.221
2022 Weilinger NL, Wicki-Stordeur LE, Groten CJ, LeDue JM, Kahle KT, MacVicar BA. KCC2 drives chloride microdomain formation in dendritic blebbing. Cell Reports. 41: 111556. PMID 36288701 DOI: 10.1016/j.celrep.2022.111556  0.22
2011 Stapleton CJ, Walcott BP, Linskey KR, Kahle KT, Nahed BV, Asaad WF. Temporal bone chondroblastoma with secondary aneurysmal bone cyst presenting as an intracranial mass with clinical seizure activity. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 857-60. PMID 21514167 DOI: 10.1016/J.Jocn.2010.11.004  0.219
2022 Duy PQ, Greenberg ABW, Butler WE, Kahle KT. Rethinking the cilia hypothesis of hydrocephalus. Neurobiology of Disease. 175: 105913. PMID 36341771 DOI: 10.1016/j.nbd.2022.105913  0.218
2012 Walcott BP, Kahle KT, Nahed BV, Coumans JV, Asaad WF. The use of intra-operative blood gas analysis in the investigation of suspected iatrogenic vascular injury. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 21: S492-4. PMID 22167452 DOI: 10.1007/S00586-011-2116-8  0.217
2011 Bashinskaya B, Nahed BV, Redjal N, Kahle KT, Walcott BP. Trends in Peptic Ulcer Disease and the Identification of Helicobacter Pylori as a Causative Organism: Population-based Estimates from the US Nationwide Inpatient Sample. Journal of Global Infectious Diseases. 3: 366-70. PMID 22224001 DOI: 10.4103/0974-777X.91061  0.216
2011 Coumans JV, Walcott BP, Butler WE, Nahed BV, Kahle KT. Volumetric analysis of syringomyelia following hindbrain decompression for Chiari malformation Type I: syringomyelia resolution follows exponential kinetics. Neurosurgical Focus. 31: E4. PMID 21882909 DOI: 10.3171/2011.6.Focus11106  0.216
2010 Nahed BV, Walcott BP, Ortman AJ, Kahle KT, Aghi M, Peterfreund RA, Coumans JV. Interval, acute onset airway obstruction associated with a fracture of the C4 vertebra in a patient with ankylosing spondylitis. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 17: 1085-8. PMID 20580996 DOI: 10.1016/J.Jocn.2009.12.010  0.215
2011 Pisapia JM, Walcott BP, Nahed BV, Kahle KT, Ogilvy CS. Cerebral revascularization for the treatment of complex intracranial aneurysms of the posterior circulation: microsurgical anatomy, techniques and outcomes. Journal of Neurointerventional Surgery. 3: 249-54. PMID 21990836 DOI: 10.1136/Jnis.2010.004176  0.215
2016 Grunwald Z, Beslow LA, Urday S, Vashkevich A, Ayres A, Greenberg SM, Goldstein JN, Leasure A, Shi FD, Kahle KT, Battey TW, Simard JM, Rosand J, Kimberly WT, Sheth KN. Perihematomal Edema Expansion Rates and Patient Outcomes in Deep and Lobar Intracerebral Hemorrhage. Neurocritical Care. PMID 27844466 DOI: 10.1007/S12028-016-0321-3  0.214
2020 Koo AB, Yeung JT, Freedman IG, Lee JH, Ahmed OM, Ma AK, Miyagishima DF, DiLuna M, Kahle K. Clinical and economic burden of neurofibromatosis type 2 in the United States. Clinical Neurology and Neurosurgery. 197: 106053. PMID 32683193 DOI: 10.1016/J.Clineuro.2020.106053  0.214
2020 Kundishora AJ, Benjamin Reeves BA, Nelson-Williams C, Hong CS, Gopal PP, Snuderl M, Kahle KT, Omay EZE. Novel EWSR1-VGLL1 fusion in a pediatric neuroepithelial neoplasm. Clinical Genetics. PMID 31925773 DOI: 10.1111/Cge.13703  0.213
2014 Walcott BP, Neal JB, Sheth SA, Kahle KT, Eskandar EN, Coumans JV, Nahed BV. The incidence of complications in elective cranial neurosurgery associated with dural closure material. Journal of Neurosurgery. 120: 278-84. PMID 24032702 DOI: 10.3171/2013.8.Jns13703  0.212
2011 Walcott BP, Nahed BV, Kahle KT, Redjal N, Coumans JV. Determination of geographic variance in stroke prevalence using Internet search engine analytics. Neurosurgical Focus. 30: E19. PMID 21631220 DOI: 10.3171/2011.2.Focus1124  0.212
2011 Walcott BP, Kahle KT, Wain JC, Borges LF. Giant thoracic meningocele associated with neurofibromatosis 1. Neurology. 76: 1943. PMID 21624995 DOI: 10.1212/Wnl.0B013E31821D7667  0.209
2011 Walcott BP, Hanak BW, Caracci JR, Redjal N, Nahed BV, Kahle KT, Coumans JV. Trends in inpatient setting laminectomy for excision of herniated intervertebral disc: Population-based estimates from the US nationwide inpatient sample. Surgical Neurology International. 2: 7. PMID 21297929 DOI: 10.4103/2152-7806.76144  0.209
2019 Elsamadicy AA, Koo AB, Lee M, Kundishora AJ, Hong CS, Hengartner AC, Camara-Quintana J, Kahle KT, DiLuna ML. Reduced influence of affective disorders on perioperative complication rates, length of hospital stay, and healthcare costs following spinal fusion for adolescent idiopathic scoliosis. Journal of Neurosurgery. Pediatrics. 1-6. PMID 31491756 DOI: 10.3171/2019.7.Peds19223  0.208
2019 Elsamadicy AA, Koo AB, Kundishora AJ, Chouairi F, Lee M, Hengartner AC, Camara-Quintana J, Kahle KT, DiLuna ML. Impact of patient and hospital-level risk factors on extended length of stay following spinal fusion for adolescent idiopathic scoliosis. Journal of Neurosurgery. Pediatrics. 1-7. PMID 31374544 DOI: 10.3171/2019.5.Peds19161  0.207
2013 Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry GT, Jensen FE. Correction: Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures Plos One. 8. DOI: 10.1371/Annotation/48A011E6-E4D0-4706-9A28-857Eba8Cfb31  0.207
2020 Date P, Ackermann P, Furey C, Fink IB, Jonas S, Khokha MK, Kahle KT, Deniz E. Author Correction: Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus. Scientific Reports. 10: 2791. PMID 32047215 DOI: 10.1038/S41598-020-59301-Y  0.206
2011 Kahle KT, Staley KJ. Response to "a claim for caution in the use of promising bumetanide to treat neonatal seizures" Journal of Child Neurology. 26: 658-659. DOI: 10.1177/0883073811401400  0.205
2017 Furey CG, Timberlake AT, Nelson-Williams C, Duran D, Li P, Jackson EM, Kahle KT. Xp22.2 Chromosomal Duplication in Familial Intracranial Arachnoid Cyst. Jama Neurology. PMID 29052703 DOI: 10.1001/Jamaneurol.2017.3399  0.204
2020 Elsamadicy AA, Koo AB, David WB, Kundishora AJ, Hong CS, Sarkozy M, Kahle KT, DiLuna M. Pre-operative headaches and obstructive hydrocephalus predict an extended length of stay following suboccipital decompression for pediatric Chiari I malformation. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 32519127 DOI: 10.1007/S00381-020-04688-2  0.202
2020 Koo AB, Elsamadicy AA, Kundishora AJ, David WB, Lee M, Hong CS, Lee V, Kahle KT, DiLuna M. Geographical variation in outcomes and costs following spinal fusion for adolescent idiopathic scoliosis. World Neurosurgery. PMID 31917315 DOI: 10.1016/J.Wneu.2019.12.175  0.199
2011 Coumans J, Walcott B, Sheth S, Nahed B, Shankar G, Kahle K. Conflict of Interest Reporting: Compliance and Effect on Study Results Presented at the 2010 North American Spine Society Annual Meeting The Spine Journal. 11: S139. DOI: 10.1016/J.Spinee.2011.08.336  0.199
2011 Aghi MK, Walcott BP, Nahed BV, Cvetanovich GL, Kahle KT, Redjal N, Coumans JV. Determinants of initial bone graft volume loss in posterolateral lumbar fusion. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 18: 1193-6. PMID 21745744 DOI: 10.1016/J.Jocn.2011.02.017  0.198
2021 Kundishora AJ, Singh AK, Allington G, Duy PQ, Ryou J, Alper SL, Jin SC, Kahle KT. Genomics of human congenital hydrocephalus. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 34232380 DOI: 10.1007/s00381-021-05230-8  0.198
2012 Walcott BP, Kahle KT, Butler WE. Endoscopic treatment of hydrocephalus. Archives of Neurology. 69: 664. PMID 22271236 DOI: 10.1001/Archneurol.2011.1766  0.196
2022 Xue Y, Gursky Z, Monte B, Koundal S, Liu X, Lee H, Michurina TV, Mellanson KA, Zhao L, Nemajerova A, Kahle KT, Takemaru KI, Enikolopov G, Peunova NI, Benveniste H. Sustained glymphatic transport and impaired drainage to the nasal cavity observed in multiciliated cell ciliopathies with hydrocephalus. Fluids and Barriers of the Cns. 19: 20. PMID 35248089 DOI: 10.1186/s12987-022-00319-x  0.192
2016 Terry AR, Kahle KT, Larvie M, Vyas JM, Stemmer-Rachamimov A. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 5-2016. A 43-Year-Old Man with Altered Mental Status and a History of Alcohol Use. The New England Journal of Medicine. 374: 671-80. PMID 26886525 DOI: 10.1056/Nejmcpc1509361  0.192
2018 Fomchenko EI, Duran D, Jin SC, Dong W, Erson-Omay EZ, Antwi P, Allocco A, Gaillard JR, Huttner A, Gunel M, DiLuna ML, Kahle KT. Novel association of germline de novo MYH9 mutation with congenital hemangioma. Cold Spring Harbor Molecular Case Studies. PMID 29903892 DOI: 10.1101/mcs.a002998  0.19
2024 Hale AT, Boudreau H, Devulapalli R, Duy PQ, Atchley TJ, Dewan MC, Goolam M, Fieggen G, Spader HL, Smith AA, Blount JP, Johnston JM, Rocque BG, Rozzelle CJ, Chong Z, ... ... Kahle KT, et al. The genetic basis of hydrocephalus: genes, pathways, mechanisms, and global impact. Fluids and Barriers of the Cns. 21: 24. PMID 38439105 DOI: 10.1186/s12987-024-00513-z  0.188
2023 Kahle KT, Duran D, Smith ER. Increasing precision in the management of pediatric neurosurgical cerebrovascular diseases with molecular genetics. Journal of Neurosurgery. Pediatrics. 1-10. PMID 36609371 DOI: 10.3171/2022.12.PEDS22332  0.181
2021 Diab NS, Barish S, Dong W, Zhao S, Allington G, Yu X, Kahle KT, Brueckner M, Jin SC. Molecular Genetics and Complex Inheritance of Congenital Heart Disease. Genes. 12. PMID 34209044 DOI: 10.3390/genes12071020  0.18
2023 Duy PQ, Kahle KT. "Floppy brain" in congenital hydrocephalus. Cerebral Cortex (New York, N.Y. : 1991). PMID 37280765 DOI: 10.1093/cercor/bhad206  0.18
2023 Mekbib KY, Muñoz W, Allington G, McGee S, Mehta NH, Shofi JP, Fortes C, Le HT, Nelson-Williams C, Nanda P, Dennis E, Kundishora AJ, Khanna A, Smith H, Ocken J, ... ... Kahle KT, et al. Human genetics and molecular genomics of Chiari malformation type 1. Trends in Molecular Medicine. PMID 37802664 DOI: 10.1016/j.molmed.2023.08.013  0.178
2021 Rahmati N, Normoyle KP, Glykys J, Dzhala VI, Lillis KP, Kahle KT, Raiyyani R, Jacob T, Staley KJ. Unique actions of GABA arising from cytoplasmic chloride microdomains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33903223 DOI: 10.1523/JNEUROSCI.3175-20.2021  0.175
2023 Kiziltug E, Duy PQ, Allington G, Timberlake AT, Kawaguchi R, Long AS, Almeida MN, DiLuna ML, Alper SL, Alperovich M, Geschwind DH, Kahle KT. Concurrent impact of de novo mutations on cranial and cortical development in nonsyndromic craniosynostosis. Journal of Neurosurgery. Pediatrics. 1-14. PMID 37890181 DOI: 10.3171/2023.8.PEDS23155  0.172
2023 Stokum JA, Shim B, Negoita S, Tsymbalyuk N, Tsymbalyuk O, Ivanova S, Keledjian K, Bryan J, Blaustein MP, Jha RM, Kahle KT, Gerzanich V, Simard JM. Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke. Science Signaling. 16: eadd6364. PMID 37279286 DOI: 10.1126/scisignal.add6364  0.172
2023 Maury EA, Walsh CA, Kahle KT. Neurosurgery elucidates somatic mutations. Science (New York, N.Y.). 382: 1360-1362. PMID 38127765 DOI: 10.1126/science.adj2244  0.171
2023 Pinard A, Ye W, Fraser SM, Rosenfeld JA, Pichurin P, Hickey SE, Guo D, Cecchi AC, Boerio ML, Guey S, Aloui C, Lee K, Kraemer M, Alyemni SO, Bamshad MJ, ... ... Kahle KT, et al. Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease. Brain : a Journal of Neurology. PMID 37253099 DOI: 10.1093/brain/awad172  0.168
2021 DeSpenza T, Carlson M, Panchagnula S, Robert S, Duy PQ, Mermin-Bunnell N, Reeves BC, Kundishora A, Elsamadicy AA, Smith H, Ocken J, Alper SL, Jin SC, Hoffman EJ, Kahle KT. PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets. Trends in Neurosciences. PMID 34625286 DOI: 10.1016/j.tins.2021.08.007  0.167
2023 Duy PQ, Mehta NH, Kahle KT. The "microcephalic hydrocephalus" paradox as a paradigm of altered neural stem cell biology. Cerebral Cortex (New York, N.Y. : 1991). PMID 37991277 DOI: 10.1093/cercor/bhad432  0.165
2022 Duy PQ, Rakic P, Alper SL, Butler WE, Walsh CA, Sestan N, Geschwind DH, Jin SC, Kahle KT. Brain ventricles as windows into brain development and disease. Neuron. 110: 12-15. PMID 34990576 DOI: 10.1016/j.neuron.2021.12.009  0.155
2023 Kundishora AJ, Kahle KT. Epigenomic dysregulation correlates with arachnoid cyst formation and neurodevelopmental symptoms. Nature Medicine. 29: 541-542. PMID 36932244 DOI: 10.1038/s41591-023-02239-1  0.155
2022 Bramall AN, Anton ES, Kahle KT, Fecci PE. Navigating the ventricles: Novel insights into the pathogenesis of hydrocephalus. Ebiomedicine. 78: 103931. PMID 35306341 DOI: 10.1016/j.ebiom.2022.103931  0.148
2022 Duy PQ, Rakic P, Alper SL, Robert SM, Kundishora AJ, Butler WE, Walsh CA, Sestan N, Geschwind DH, Jin SC, Kahle KT. A neural stem cell paradigm of pediatric hydrocephalus. Cerebral Cortex (New York, N.Y. : 1991). PMID 36097331 DOI: 10.1093/cercor/bhac341  0.147
2021 Qi C, Feng I, Costa AR, Pinto-Costa R, Neil JE, Caluseriu O, Li D, Ganetzky RD, Brasch-Andersen C, Fagerberg C, Hansen LK, Bupp C, Muraresku CC, Ruan X, Kang B, ... ... Kahle KT, et al. Variants in ADD1 cause intellectual disability, corpus callosum dysgenesis, and ventriculomegaly in humans. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34906466 DOI: 10.1016/j.gim.2021.09.014  0.146
2022 Qureshi HM, Mekbib KY, Allington G, Elsamadicy AA, Duy PQ, Kundishora AJ, Jin SC, Kahle KT. Familial and syndromic forms of arachnoid cyst implicate genetic factors in disease pathogenesis. Cerebral Cortex (New York, N.Y. : 1991). PMID 35851401 DOI: 10.1093/cercor/bhac257  0.138
2021 Diab NS, King S, Dong W, Allington G, Sheth A, Peters ST, Kahle KT, Jin SC. Analysis workflow to assess genetic variants from human whole-exome sequencing. Star Protocols. 2: 100383. PMID 33748785 DOI: 10.1016/j.xpro.2021.100383  0.134
2021 Robert SM, Reeves BC, Marlier A, Duy PQ, DeSpenza T, Kundishora A, Kiziltug E, Singh A, Allington G, Alper SL, Kahle KT. Inflammatory hydrocephalus. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 34164718 DOI: 10.1007/s00381-021-05255-z  0.133
2018 Furey C, Antwi P, Duran D, Timberlake AT, Nelson-Williams C, Matouk CC, DiLuna ML, Günel M, Kahle KT. 9p24 triplication and 15q13 deletion in syndromic hydrocephalus with diffuse villous hyperplasia of the choroid plexus. Cold Spring Harbor Molecular Case Studies. PMID 29895553 DOI: 10.1101/mcs.a003145  0.132
2023 Greenberg ABW, Mehta NH, Mekbib KY, Kiziltug E, Smith HR, Hyman BT, Chan D, Curry WT, Arnold SE, Frosch MP, Duy PQ, Kahle KT. Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis. Cerebral Cortex (New York, N.Y. : 1991). PMID 37814356 DOI: 10.1093/cercor/bhad374  0.131
2021 Fomchenko EI, Reeves BC, Sullivan W, Marks AM, Huttner A, Kahle KT, Erson-Omay EZ. Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma. Molecular Genetics & Genomic Medicine. e1597. PMID 33448156 DOI: 10.1002/mgg3.1597  0.128
2021 Allington G, Duy PQ, Ryou J, Singh A, Kiziltug E, Robert SM, Kundishora AJ, King S, Haider S, Kahle KT, Jin SC. Genomic approaches to improve the clinical diagnosis and management of patients with congenital hydrocephalus. Journal of Neurosurgery. Pediatrics. 1-10. PMID 34715668 DOI: 10.3171/2021.8.PEDS21368  0.126
2022 Wang YC, Wu Y, Choi J, Allington G, Zhao S, Khanfar M, Yang K, Fu PY, Wrubel M, Yu X, Mekbib KY, Ocken J, Smith H, Shohfi J, Kahle KT, et al. Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy. Journal of Personalized Medicine. 12. PMID 35207663 DOI: 10.3390/jpm12020175  0.115
2018 Antwi P, Hong CS, Duran D, Sheng Chih J, Dong W, DiLuna M, Kahle KT. A novel association of campomelic dysplasia with hydrocephalus due to an unbalanced chromosomal translocation upstream of SOX9. Cold Spring Harbor Molecular Case Studies. PMID 29695406 DOI: 10.1101/mcs.a002766  0.113
2020 Reeves BC, Karimy JK, Kundishora AJ, Mestre H, Cerci HM, Matouk C, Alper SL, Lundgaard I, Nedergaard M, Kahle KT. Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus. Trends in Molecular Medicine. PMID 31959516 DOI: 10.1016/j.molmed.2019.11.008  0.112
2023 Lucas AT, Lin AE, Cohen A, Muñoz W, Kahle KT, Shin JH, Buch K, Sahai I, Carroll RW. Atlantoaxial instability associated with ALDH18A1 mutation. American Journal of Medical Genetics. Part A. PMID 37655511 DOI: 10.1002/ajmg.a.63388  0.112
2022 Koch MJ, Duy PQ, Grannan BL, Patel AB, Raymond SB, Agarwalla PK, Kahle KT, Butler WE. Angiographic Pulse Wave Coherence in the Human Brain. Frontiers in Bioengineering and Biotechnology. 10: 873530. PMID 35592552 DOI: 10.3389/fbioe.2022.873530  0.109
2010 Kahle KT, Staley KJ. Cation-chloride cotransporters as pharmacological targets in the treatment of epilepsy Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 489-500. DOI: 10.1016/B978-0-12-374373-2.00024-8  0.109
2024 Greenberg ABW, Mekbib KY, Mehta NH, Kiziltug E, Duy PQ, Smith HR, Junkkari A, Leinonen V, Hyman BT, Chan D, Curry WT, Arnold SE, Barker Ii FG, Frosch MP, Kahle KT. Utility of cortical tissue analysis in normal pressure hydrocephalus. Cerebral Cortex (New York, N.Y. : 1991). PMID 38275188 DOI: 10.1093/cercor/bhae001  0.1
2021 Elsamadicy AA, Koo AB, David WB, Lee V, Zogg CK, Kundishora AJ, Hong C, Reeves BC, Sarkozy M, Kahle KT, DiLuna M. Post-traumatic seizures following pediatric traumatic brain injury. Clinical Neurology and Neurosurgery. 203: 106556. PMID 33636505 DOI: 10.1016/j.clineuro.2021.106556  0.082
2023 Mehta NH, Greenberg ABW, Kahle KT. The Efficacy of Endoscopic Third Ventriculostomy for Idiopathic Normal Pressure Hydrocephalus. World Neurosurgery. 179: 158-166. PMID 37625638 DOI: 10.1016/j.wneu.2023.08.071  0.081
2023 Ahmad N, Fazeli W, Schließke S, Lesca G, Gokce-Samar Z, Mekbib KY, Jin SC, Burton J, Hoganson G, Petersen A, Gracie S, Granger L, Bartels E, Oppermann H, Kundishora A, ... ... Kahle KT, et al. De Novo Variants in RAB11B Cause Various Degrees of Global Developmental Delay and Intellectual Disability in Children. Pediatric Neurology. 148: 164-171. PMID 37734130 DOI: 10.1016/j.pediatrneurol.2023.08.023  0.08
2023 Greenberg ABW, Mehta NH, Allington G, Jin SC, Moreno-De-Luca A, Kahle KT. Molecular Diagnostic Yield of Exome Sequencing in Patients With Congenital Hydrocephalus: A Systematic Review and Meta-Analysis. Jama Network Open. 6: e2343384. PMID 37991765 DOI: 10.1001/jamanetworkopen.2023.43384  0.078
2021 Puthenpura V, DeNunzio NJ, Zeng X, Giantsoudi D, Aboian M, Ebb D, Kahle KT, Yock TI, Marks AM. Radiation Necrosis with Proton Therapy in a Patient with Aarskog-Scott Syndrome and Medulloblastoma. International Journal of Particle Therapy. 8: 58-65. PMID 35127977 DOI: 10.14338/IJPT-21-00013.1  0.076
2023 McLaren JR, Kahle KT, Richardson RM, Chu CJ. Epilepsy Surgery for Cognitive Improvement in Epileptic Encephalopathy. Neurosurgery Clinics of North America. 35: 49-59. PMID 38000841 DOI: 10.1016/j.nec.2023.08.002  0.074
2021 Koo AB, Elsamadicy AA, Lin IH, David WB, Reeves BC, Santarosa C, Cord B, Malhotra A, Kahle KT, Matouk CC. Patient Risk Factors Associated with 30- and 90- Day Readmission after Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients: A Nationwide Readmission Study. World Neurosurgery. PMID 33862298 DOI: 10.1016/j.wneu.2021.04.010  0.073
2013 Kahle KT, Duhaime AC. Intracranial-pressure monitoring in traumatic brain injury. The New England Journal of Medicine. 368: 1750. PMID 23635062 DOI: 10.1056/NEJMc1301076#SA5  0.068
2020 Elsamadicy AA, Koo AB, David WB, Lee V, Zogg CK, Kundishora AJ, Hong CS, DeSpenza T, Reeves BC, Kahle KT, DiLuna M. Comparison of epidemiology, treatments, and outcomes in pediatric versus adult ependymoma. Neuro-Oncology Advances. 2: vdaa019. PMID 32642681 DOI: 10.1093/noajnl/vdaa019  0.065
2011 Walcott BP, Kahle KT. Blast-related traumatic brain injury in U.S. military personnel. The New England Journal of Medicine. 365: 860. PMID 21879908 DOI: 10.1056/NEJMc1107891#SA2  0.059
2015 Khanna A, Simard JM, Kahle KT. Progesterone in traumatic brain injury. The New England Journal of Medicine. 372: 1765-6. PMID 25923560 DOI: 10.1056/NEJMc1503138#SA2  0.058
2021 Elsamadicy AA, Koo AB, David WB, Freedman IG, Kundishora AJ, Hong CS, Sarkozy M, Sciubba DM, Kahle KT, DiLuna M. Impact of race on outcomes and healthcare utilization following spinal fusion for adolescent idiopathic scoliosis. Clinical Neurology and Neurosurgery. 206: 106634. PMID 33979695 DOI: 10.1016/j.clineuro.2021.106634  0.054
2020 Sullivan W, Reeves BC, Duy PQ, Nelson-Williams C, Dong W, Jin SC, Kahle KT. Exome Sequencing as a Potential Diagnostic Adjunct in Sporadic Congenital Hydrocephalus. Jama Pediatrics. PMID 33196764 DOI: 10.1001/jamapediatrics.2020.4878  0.054
2011 Simard JM, Kahle KT, Walcott BP. Craniectomy in diffuse traumatic brain injury. The New England Journal of Medicine. 365: 374; author reply 37. PMID 21793753 DOI: 10.1056/NEJMc1106421#SA3  0.052
2021 Dinis J, Junn A, Kahle K, Alperovich M. Extended Scalp Expansion for Larger Defects During Staged Cranioplasty. The Journal of Craniofacial Surgery. PMID 34723917 DOI: 10.1097/SCS.0000000000008291  0.05
2021 Elsamadicy AA, Freedman IG, Koo AB, David WB, Havlik J, Kundishora AJ, Sciubba DM, Kahle KT, DiLuna M. The effects of pulmonary risk factors on hospital resource utilization after posterior spinal fusion for adolescent idiopathic scoliosis correction. World Neurosurgery. PMID 33548534 DOI: 10.1016/j.wneu.2021.01.109  0.05
2021 Duy PQ, Kahle KT. Intraventricular Cerebrospinal Fluid Turbulence in Pediatric Communicating Hydrocephalus. Neurology. PMID 34031199 DOI: 10.1212/WNL.0000000000012237  0.049
2013 Walcott BP, Kahle KT, Simard JM. The DECRA trial and decompressive craniectomy in diffuse traumatic brain injury: is decompression really ineffective? World Neurosurgery. 79: 80-1. PMID 23159659 DOI: 10.1016/j.wneu.2012.11.014  0.048
2020 Elsamadicy AA, Freedman IG, Koo AB, David WB, Havlik J, Kundishora AJ, Hong CS, Sciubba DM, Kahle KT, DiLuna M. Impact of pre-operative anemia on outcomes following posterior spinal fusion for adolescent idiopathic scoliosis. World Neurosurgery. PMID 33091648 DOI: 10.1016/j.wneu.2020.10.074  0.042
2021 Junn A, Dinis J, Kahle KT, Alperovich M. Stepwise Reconstruction of a Large, Self-Inflicted Calvarial Defect. The Journal of Craniofacial Surgery. PMID 34560747 DOI: 10.1097/SCS.0000000000008192  0.038
2022 Marra CM, Rohatgi S, Bloom AK, Kahle KT, Haj AK. Case 25-2022: A 25-Year-Old Woman with Headache and Blurred Vision. The New England Journal of Medicine. 387: 641-650. PMID 36070713 DOI: 10.1056/NEJMcpc2201241  0.031
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