| Year |
Citation |
Score |
| 2007 |
Woodard CL, Keenan SM, Gerena L, Welsh WJ, Geyer JA, Waters NC. Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk. Bioorganic & Medicinal Chemistry Letters. 17: 4961-6. PMID 17588749 DOI: 10.1016/J.Bmcl.2007.06.032 |
0.374 |
|
| 2005 |
Peng Y, Keenan SM, Welsh WJ. Structural model of the Plasmodium CDK, Pfmrk, a novel target for malaria therapeutics. Journal of Molecular Graphics & Modelling. 24: 72-80. PMID 16046158 DOI: 10.1016/J.Jmgm.2005.06.002 |
0.312 |
|
| 2004 |
Keenan SM, Lents NH, Baldassare JJ. Expression of cyclin E renders cyclin D-CDK4 dispensable for inactivation of the retinoblastoma tumor suppressor protein, activation of E2F, and G1-S phase progression. The Journal of Biological Chemistry. 279: 5387-96. PMID 14645251 DOI: 10.1074/Jbc.M310383200 |
0.441 |
|
| 2004 |
Keenan SM, Welsh WJ. Characteristics of the Plasmodium falciparum PK5 ATP-binding site: implications for the design of novel antimalarial agents. Journal of Molecular Graphics & Modelling. 22: 241-7. PMID 14629982 DOI: 10.1016/J.Jmgm.2003.09.002 |
0.331 |
|
| 2002 |
Lents NH, Keenan SM, Bellone C, Baldassare JJ. Activation and phosphorylation on Thr-160 of nuclear-targeted CDK2 Is ERK dependent. Annals of the New York Academy of Sciences. 973: 265-7. PMID 12485874 DOI: 10.1111/J.1749-6632.2002.Tb04646.X |
0.413 |
|
| 2002 |
Lents NH, Keenan SM, Bellone C, Baldassare JJ. Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. The Journal of Biological Chemistry. 277: 47469-75. PMID 12359725 DOI: 10.1074/Jbc.M207425200 |
0.492 |
|
| 2001 |
Keenan SM, Baldassare JJ. Molecular scaffold protein and cellular responses. Trends in Endocrinology and Metabolism: Tem. 12: 184-6. PMID 11397637 DOI: 10.1016/S1043-2760(01)00404-0 |
0.346 |
|
| 2001 |
Keenan SM, Bellone C, Baldassare JJ. Cyclin-dependent kinase 2 nucleocytoplasmic translocation is regulated by extracellular regulated kinase. The Journal of Biological Chemistry. 276: 22404-9. PMID 11304535 DOI: 10.1074/Jbc.M100409200 |
0.461 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2010 |
Jirage D, Keenan SM, Waters NC. Exploring novel targets for antimalarial drug discovery: plasmodial protein kinases. Infectious Disorders Drug Targets. 10: 134-46. PMID 20334624 |
0.287 |
|
| 2005 |
Keenan SM, Geyer JA, Welsh WJ, Prigge ST, Waters NC. Rational inhibitor design and iterative screening in the identification of selective plasmodial cyclin dependent kinase inhibitors. Combinatorial Chemistry & High Throughput Screening. 8: 27-38. PMID 15720195 DOI: 10.2174/1386207053328183 |
0.268 |
|
| 2013 |
Bullard KM, DeLisle RK, Keenan SM. Malarial kinases: novel targets for in silico approaches to drug discovery. Methods in Molecular Biology (Clifton, N.J.). 993: 205-29. PMID 23568473 DOI: 10.1007/978-1-62703-342-8_14 |
0.254 |
|
| 2005 |
Nur-E-Kamal A, Zhang A, Keenan SM, Wang XI, Seraj J, Satoh T, Meiners S, Welsh WJ. Requirement of activated Cdc42-associated kinase for survival of v-Ras-transformed mammalian cells. Molecular Cancer Research : McR. 3: 297-305. PMID 15886301 DOI: 10.1158/1541-7786.Mcr-04-0152 |
0.223 |
|
| 2015 |
Bullard KM, Broccardo C, Keenan SM. Effects of cyclin-dependent kinase inhibitor Purvalanol B application on protein expression and developmental progression in intra-erythrocytic Plasmodium falciparum parasites. Malaria Journal. 14: 147. PMID 25879664 DOI: 10.1186/S12936-015-0655-X |
0.191 |
|
| 2009 |
Peng Y, Zhang Q, Arora S, Keenan SM, Kortagere S, Wannemacher KM, Howells RD, Welsh WJ. Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways. Bioorganic & Medicinal Chemistry. 17: 6442-50. PMID 19646882 DOI: 10.1016/J.Bmc.2009.07.007 |
0.19 |
|
| 2009 |
Geyer JA, Keenan SM, Woodard CL, Thompson PA, Gerena L, Nichols DA, Gutteridge CE, Waters NC. Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones. Bioorganic & Medicinal Chemistry Letters. 19: 1982-5. PMID 19250824 DOI: 10.1016/j.bmcl.2009.02.042 |
0.165 |
|
| 2012 |
Stahla-Beek HJ, April DG, Saeedi BJ, Hannah AM, Keenan SM, Geiss BJ. Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme. Journal of Virology. 86: 8730-9. PMID 22674988 DOI: 10.1128/Jvi.00384-12 |
0.16 |
|
| 2015 |
Bullard KM, Gullberg RC, Soltani E, Steel JJ, Geiss BJ, Keenan SM. Murine Efficacy and Pharmacokinetic Evaluation of the Flaviviral NS5 Capping Enzyme 2-Thioxothiazolidin-4-One Inhibitor BG-323. Plos One. 10: e0130083. PMID 26075394 DOI: 10.1371/Journal.Pone.0130083 |
0.156 |
|
| 2007 |
Zhang Q, Peng Y, Wang XI, Keenan SM, Arora S, Welsh WJ. Highly potent triazole-based tubulin polymerization inhibitors. Journal of Medicinal Chemistry. 50: 749-54. PMID 17249649 DOI: 10.1021/Jm061142S |
0.156 |
|
| 2003 |
Williams JB, Keenan SM, Gan Q, Knuepfer MM. Hemodynamic response profile predicts susceptibility to cocaine-induced toxicity. European Journal of Pharmacology. 464: 189-96. PMID 12620513 DOI: 10.1016/S0014-2999(03)01429-8 |
0.15 |
|
| 2009 |
Arora S, Wang XI, Keenan SM, Andaya C, Zhang Q, Peng Y, Welsh WJ. Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity. Cancer Research. 69: 1910-5. PMID 19223556 DOI: 10.1158/0008-5472.Can-08-0877 |
0.132 |
|
| 2003 |
Paula S, Tabet MR, Keenan SM, Welsh WJ, Ball WJ. Three-dimensional structure-activity relationship modeling of cocaine binding to two monoclonal antibodies by comparative molecular field analysis. Journal of Molecular Biology. 325: 515-30. PMID 12498800 DOI: 10.1016/S0022-2836(02)01235-4 |
0.131 |
|
| 2003 |
Ball WJ, Farr CD, Paula S, Keenan SM, Delisle RK, Welsh WJ. Three-dimensional structure-activity relationship modeling of digoxin inhibition and docking to Na+,K+-ATPase. Annals of the New York Academy of Sciences. 986: 296-7. PMID 12763827 DOI: 10.1111/J.1749-6632.2003.Tb07191.X |
0.116 |
|
| 2005 |
Peng Y, Keenan SM, Zhang Q, Welsh WJ. 3D-QSAR comparative molecular field analysis on delta opioid receptor agonist SNC80 and its analogs. Journal of Molecular Graphics & Modelling. 24: 25-33. PMID 15950508 DOI: 10.1016/J.Jmgm.2005.05.001 |
0.109 |
|
| 2011 |
Geiss BJ, Stahla-Beek HJ, Hannah AM, Gari HH, Henderson BR, Saeedi BJ, Keenan SM. A high-throughput screening assay for the identification of flavivirus NS5 capping enzyme GTP-binding inhibitors: implications for antiviral drug development. Journal of Biomolecular Screening. 16: 852-61. PMID 21788392 DOI: 10.1177/1087057111412183 |
0.108 |
|
| 2009 |
Geiss BJ, Stahla H, Hannah AM, Gari AM, Keenan SM. Focus on flaviviruses: current and future drug targets. Future Medicinal Chemistry. 1: 327-44. PMID 20165556 DOI: 10.4155/Fmc.09.27 |
0.104 |
|
| 2005 |
Keenan SM, DeLisle RK, Welsh WJ, Paula S, Ball WJ. Elucidation of the Na+, K+-ATPase digitalis binding site. Journal of Molecular Graphics & Modelling. 23: 465-75. PMID 15886034 DOI: 10.1016/J.Jmgm.2005.02.001 |
0.102 |
|
| 2002 |
Yu SJ, Keenan SM, Tong W, Welsh WJ. Influence of the structural diversity of data sets on the statistical quality of three-dimensional quantitative structure-activity relationship (3D-QSAR) models: predicting the estrogenic activity of xenoestrogens. Chemical Research in Toxicology. 15: 1229-34. PMID 12387618 DOI: 10.1021/Tx0255875 |
0.092 |
|
| 2005 |
Peng Y, Keenan SM, Zhang Q, Kholodovych V, Welsh WJ. 3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies. Journal of Medicinal Chemistry. 48: 1620-9. PMID 15743203 DOI: 10.1021/Jm049117E |
0.081 |
|
| 2009 |
Geiss BJ, Thompson AA, Andrews AJ, Sons RL, Gari HH, Keenan SM, Peersen OB. Analysis of flavivirus NS5 methyltransferase cap binding. Journal of Molecular Biology. 385: 1643-54. PMID 19101564 DOI: 10.1016/J.Jmb.2008.11.058 |
0.078 |
|
| 2006 |
Zhang Q, Keenan SM, Peng Y, Nair AC, Yu SJ, Howells RD, Welsh WJ. Discovery of novel triazole-based opioid receptor antagonists. Journal of Medicinal Chemistry. 49: 4044-7. PMID 16821764 DOI: 10.1021/Jm0601250 |
0.078 |
|
| 2021 |
Grunspan DZ, Holt EA, Keenan SM. Instructional Communities of Practice during COVID-19: Social Networks and Their Implications for Resilience. Journal of Microbiology & Biology Education. 22. PMID 33884061 DOI: 10.1128/jmbe.v22i1.2505 |
0.052 |
|
| 2003 |
Christoffers KH, Li H, Keenan SM, Howells RD. Purification and mass spectrometric analysis of the mu opioid receptor. Brain Research. Molecular Brain Research. 118: 119-31. PMID 14559361 |
0.041 |
|
| 2007 |
Berent GP, Kelly RR, Aldersley S, Schmitz KL, Khalsa BK, Panara J, Keenan S. Focus-on-form instructional methods promote deaf college students' improvement in English grammar. Journal of Deaf Studies and Deaf Education. 12: 8-24. PMID 16887881 DOI: 10.1093/deafed/enl009 |
0.028 |
|
| Hide low-probability matches. |