Year |
Citation |
Score |
2022 |
McClellan B, Pham T, Harlow B, Lee G, Quach D, Jolly C, Brenner A, deGraffenried L. Modulation of Breast Cancer Cell FASN Expression by Obesity-Related Systemic Factors. Breast Cancer : Basic and Clinical Research. 16: 11782234221111374. PMID 36035625 DOI: 10.1177/11782234221111374 |
0.5 |
|
2021 |
Gruslova A, McClellan B, Balinda HU, Viswanadhapalli S, Alers V, Sareddy GR, Huang T, Garcia M, deGraffenried L, Vadlamudi RK, Brenner AJ. FASN inhibition as a potential treatment for endocrine-resistant breast cancer. Breast Cancer Research and Treatment. 187: 375-386. PMID 33893909 DOI: 10.1007/s10549-021-06231-6 |
0.341 |
|
2021 |
De Angulo A, Travis P, Galvan GC, Jolly C, deGraffenried L. Obesity-Modified CD4+ T-Cells Promote an Epithelial-Mesenchymal Transition Phenotype in Prostate Cancer Cells. Nutrition and Cancer. 1-10. PMID 33715540 DOI: 10.1080/01635581.2021.1898649 |
0.434 |
|
2020 |
Harlow B, Davalos A, Brenner A, Jolly C, Tiziani S, Hursting S, deGraffenried L. Abstract P1-08-02: Omega-3 fatty acids modulate the ability of obese conditions to induce of a proinflammatory phenotype in fibroblasts Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P1-08-02 |
0.618 |
|
2018 |
Liss MA, Rickborn L, DiGiovanni J, Bacich D, DeGraffenried LA, Parihar M, Thompson IM, Sharp ZD. mTOR inhibitors for treatment of low-risk prostate cancer. Medical Hypotheses. 117: 63-68. PMID 30077200 DOI: 10.1016/J.Mehy.2018.06.004 |
0.306 |
|
2018 |
Bowers LW, Rossi EL, McDonell SB, Doerstling SS, Khatib SA, Lineberger CG, Albright JE, Tang X, deGraffenried LA, Hursting SD. Leptin Signaling Mediates Obesity-associated CSC Enrichment and EMT in Preclinical TNBC Models. Molecular Cancer Research : McR. PMID 29453319 DOI: 10.1158/1541-7786.Mcr-17-0508 |
0.446 |
|
2018 |
Pham T, Oberman A, Kim I, Lee G, Quach D, Galván G, Jolly C, Cavazos D, Brenner A, deGraffenried L. Abstract P3-07-10: Modulation of FASN under obese conditions Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-07-10 |
0.4 |
|
2018 |
Winikka L, Quach D, Harlow B, Brenner A, Munoz N, Tiziani S, deGraffenried L. Abstract P1-03-12: The ratio of omega-3 to omega-6 PUFAs impact cancer cell phenotype in the tumor microenvironment Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P1-03-12 |
0.576 |
|
2018 |
Angulo AD, Travis P, Jolly C, deGraffenried L. Abstract 61: Obesity-induced T cell senescence contributes to prostate cancer progression Cancer Research. 78: 61-61. DOI: 10.1158/1538-7445.Am2018-61 |
0.47 |
|
2018 |
Harlow B, Davalos A, Brenner A, Jolly C, Hursting S, deGraffenried L. Abstract 5131: Obese conditions induce changes in stromal fibroblast phenotype Cancer Research. 78: 5131-5131. DOI: 10.1158/1538-7445.Am2018-5131 |
0.598 |
|
2017 |
Rossi EL, Dunlap SM, Bowers LW, Khatib SA, Doerstling SS, Smith LA, Sharma MA, Holley D, Brown PH, Estecio MR, Kusewitt DF, deGraffenried LA, Bultman SJ, Hursting SD. Energy balance modulation impacts epigenetic reprogramming, ERα and ERβ expression and mammary tumor development in MMTV-neu transgenic mice. Cancer Research. PMID 28373182 DOI: 10.1158/0008-5472.Can-16-2795 |
0.367 |
|
2017 |
Quach D, Lengfelder L, Winnika L, Harlow B, Galvan G, Jolly C, Brenner A, deGraffenried L. Abstract P6-17-03: The importance of the ultimate ratio of Omega-6 to Omega-3 fatty acids in the efficacy of fish oil supplements in suppressing inflammation in obese postmenopausal women Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-17-03 |
0.544 |
|
2017 |
Pham T, Lee G, Quach D, Galvan G, Jolly C, Cavazos D, Brenner A, deGraffenried L. Abstract P6-02-05: Modulation of FASN under obese conditions Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-02-05 |
0.4 |
|
2017 |
Hayden A, Quach D, Galvan G, Patodia R, Brenner A, deGraffenried L. Abstract P4-04-03: Obesity-induced EMT in luminal A breast cancer cells Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-04-03 |
0.6 |
|
2017 |
Brenner A, Lengfelder L, Quach D, Cavazos D, Ramirez R, Gruslova A, Kist K, Lathrup K, Kaklamani V, Beeram M, deGraffenried L. Abstract P1-09-16: Randomized study of COX2 inhibition on systemic inflammation in obese and non-obese subjects Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-09-16 |
0.554 |
|
2017 |
Quach DK, Harlow B, Winikka L, Brenner A, Beeram M, Tiziani S, Lengfelder L, Galvan G, Jolly C, deGraffenried L. Abstract 233: The impact of omega-3 fatty acid supplementation on obesity-induced inflammatory signaling within the breast tumor microenvironment Cancer Research. 77: 233-233. DOI: 10.1158/1538-7445.Am2017-233 |
0.595 |
|
2016 |
Chen CH, Fabian C, Hursting S, deGraffenried LA. Breast Cancer Genetic and Molecular Subtype Impacts Response to Omega-3 Fatty Acid Ethyl Esters. Nutrition and Cancer. 1-13. PMID 27367296 DOI: 10.1080/01635581.2016.1192199 |
0.446 |
|
2016 |
Lengfelder L, Brenner A, Bowers L, Apte S, Galván G, Kist K, deGraffenried L. Abstract P3-14-12: Phase 0 study evaluating COX2 inhibition on circulating PGE2 levels from obese subjects Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-14-12 |
0.54 |
|
2015 |
Bowers LW, Wiese M, Brenner AJ, Rossi EL, Tekmal RR, Hursting SD, deGraffenried LA. Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway. Plos One. 10: e0145452. PMID 26709918 DOI: 10.1371/journal.pone.0145452 |
0.546 |
|
2015 |
Bowers LW, deGraffenried LA. Targeting the COX-2 Pathway to Improve Therapeutic Response in the Obese Breast Cancer Patient Population. Current Pharmacology Reports. 1: 336-345. PMID 26442202 DOI: 10.1007/s40495-015-0041-y |
0.539 |
|
2015 |
Ford NA, Rossi EL, Barnett K, Yang P, Bowers LW, Hideka B, Kimler BF, Carlson SE, Shureiqi I, deGraffenried LA, Fabian CJ, Hursting SD. Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-Like and Claudin Low Breast Cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 26100521 DOI: 10.1158/1940-6207.Capr-15-0018 |
0.481 |
|
2015 |
Bowers LW, Rossi EL, O'Flanagan CH, deGraffenried LA, Hursting SD. The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link. Frontiers in Endocrinology. 6: 77. PMID 26029167 DOI: 10.3389/fendo.2015.00077 |
0.317 |
|
2015 |
De Angulo A, Faris R, Daniel B, Jolly C, deGraffenried L. Age-related increase in IL-17 activates pro-inflammatory signaling in prostate cells. The Prostate. 75: 449-62. PMID 25560177 DOI: 10.1002/Pros.22931 |
0.317 |
|
2015 |
Bowers LW, Brenner AJ, Hursting SD, Tekmal RR, deGraffenried LA. Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production. Breast Cancer Research and Treatment. 149: 49-57. PMID 25476497 DOI: 10.1007/s10549-014-3223-0 |
0.493 |
|
2015 |
Chen CH, Garcia L, Fabian C, Hursting S, deGraffenried L. Abstract P5-14-01: Docosahexanoic acid's modulation of survival and invasion is associated with altered CCL20/CCR6 chemokine levels and signaling in hyperplastic, DCIS and metastatic breast cancer cell lines Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P5-14-01 |
0.547 |
|
2014 |
Cavazos DA, Degraffenried MJ, Apte SA, Bowers LW, Whelan KA, Degraffenried LA. Obesity promotes aerobic glycolysis in prostate cancer cells Nutrition and Cancer. 66: 1179-1186. PMID 25264717 DOI: 10.1080/01635581.2014.951738 |
0.427 |
|
2014 |
Bowers LW, Maximo IX, Brenner AJ, Beeram M, Hursting SD, Price RS, Tekmal RR, Jolly CA, deGraffenried LA. NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions. Cancer Research. 74: 4446-57. PMID 25125682 DOI: 10.1158/0008-5472.Can-13-3603 |
0.538 |
|
2013 |
Bowers LW, Cavazos DA, Maximo IX, Brenner AJ, Hursting SD, deGraffenried LA. Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression. Breast Cancer Research : Bcr. 15: R59. PMID 23880059 DOI: 10.1186/Bcr3453 |
0.529 |
|
2013 |
Apte SA, Cavazos DA, Whelan KA, Degraffenried LA. A low dietary ratio of omega-6 to omega-3 fatty acids may delay progression of prostate cancer Nutrition and Cancer. 65: 556-562. PMID 23659447 DOI: 10.1080/01635581.2013.775316 |
0.328 |
|
2013 |
De Angulo A, Faris R, Cavazos D, Jolly C, Daniel B, DeGraffenried L. Age-related alterations in T-lymphocytes modulate key pathways in prostate tumorigenesis. The Prostate. 73: 855-64. PMID 23532664 DOI: 10.1002/Pros.22631 |
0.374 |
|
2013 |
De Angel RE, Conti CJ, Wheatley KE, Brenner AJ, Otto G, Degraffenried LA, Hursting SD. The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001. Molecular Carcinogenesis. 52: 446-58. PMID 22290600 DOI: 10.1002/mc.21878 |
0.429 |
|
2013 |
Wiese M, Bowers L, Tekmal R, Brenner A, Hursting S, deGraffenried L. Abstract P5-05-08: Obesity suppresses estrogen receptor beta expression in breast cancer cells via a HER2-mediated pathway Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P5-05-08 |
0.605 |
|
2013 |
Fabian C, Kimler B, Petroff B, Zalles C, Metheny T, Nydegger J, Box J, Phillips T, Hidaka B, Carlson S, deGraffenried L, Hursting S. Abstract P4-10-01: High dose omega-3 fatty acid supplementation modulates breast tissue biomarkers in post-menopausal women at high risk for development of breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-10-01 |
0.452 |
|
2013 |
Chen C, Quach D, Bowers L, Fabian C, Hursting S, deGraffenried L. Abstract P4-09-02: Omega-3 ethyl esters suppress breast cancer growth by modulating inflammatory signaling Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-09-02 |
0.544 |
|
2013 |
Bowers L, Maximo I, Tekmal R, Hursting S, Beeram M, Brenner A, deGraffenried L. Abstract P1-06-01: NSAID use attenuates breast cancer recurrence in obese women: Role of prostaglandin-aromatase interactions Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P1-06-01 |
0.605 |
|
2012 |
Chen CH, deGraffenried LA. Anethole suppressed cell survival and induced apoptosis in human breast cancer cells independent of estrogen receptor status. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 19: 763-7. PMID 22464689 DOI: 10.1016/j.phymed.2012.02.017 |
0.446 |
|
2012 |
Price RS, Cavazos DA, De Angel RE, Hursting SD, deGraffenried LA. Obesity-related systemic factors promote an invasive phenotype in prostate cancer cells. Prostate Cancer and Prostatic Diseases. 15: 135-43. PMID 22333686 DOI: 10.1038/Pcan.2011.54 |
0.514 |
|
2012 |
Chen CH, Fabian C, Hursting S, deGraffenried L. Abstract 5444:In vitromodeling for breast cancer prevention - omega-3 ethyl esters functioning as preventive agents in 21T series models Cancer Research. 72: 5444-5444. DOI: 10.1158/1538-7445.Am2012-5444 |
0.53 |
|
2012 |
Alejandra DA, Faris R, Cavazos D, deGraffenried L, Jolly C. Abstract 3553: Modulation of pro-inflammatory signaling pathways by aging T-lymphocytes contributes to a more malignant phenotype in prostate epithelial cells Cancer Research. 72: 3553-3553. DOI: 10.1158/1538-7445.Am2012-3553 |
0.4 |
|
2012 |
Bowers LW, Angel RD, Tekmal R, Brenner A, Hursting S, deGraffenried L. Abstract 3071: Obesity-associated growth factor signaling upregulates aromatase expression and estrogen receptor activity in breast cancer cells Cancer Research. 72: 3071-3071. DOI: 10.1158/1538-7445.Am2012-3071 |
0.601 |
|
2011 |
Tiwary R, Yu W, deGraffenried LA, Sanders BG, Kline K. Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer. Breast Cancer Research : Bcr. 13: R120. PMID 22115051 DOI: 10.1186/Bcr3063 |
0.33 |
|
2011 |
Friedrichs W, Ruparel SB, Marciniak RA, deGraffenried L. Omega-3 fatty acid inhibition of prostate cancer progression to hormone independence is associated with suppression of mTOR signaling and androgen receptor expression. Nutrition and Cancer. 63: 771-7. PMID 21667400 DOI: 10.1080/01635581.2011.570892 |
0.406 |
|
2011 |
Mishra S, Tang Y, Wang L, deGraffenried L, Yeh IT, Werner S, Troyer D, Copland JA, Sun LZ. Blockade of transforming growth factor-beta (TGFβ) signaling inhibits osteoblastic tumorigenesis by a novel human prostate cancer cell line. The Prostate. 71: 1441-54. PMID 21321980 DOI: 10.1002/Pros.21361 |
0.406 |
|
2011 |
Chen CH, Fabian C, Hursting S, deGraffenried L. Abstract 5586: Omega-3 ethyl esters: Differential involvement of NF-kB in suppressing cell viability of genetically diverse breast cancer cell lines Cancer Research. 71: 5586-5586. DOI: 10.1158/1538-7445.Am2011-5586 |
0.512 |
|
2011 |
Bowers LW, Angel RD, Cavazos D, Hursting S, Brenner A, deGraffenried L. Abstract 531: Obesity-associated growth factor signaling upregulates aromatase expression in breast cancer cells Cancer Research. 71: 531-531. DOI: 10.1158/1538-7445.Am2011-531 |
0.591 |
|
2011 |
Bowers L, Brenner A, Li R, Tekmal R, deGraffenried L. P4-02-08: Obesity-Induced Aromatase Expression in the Breast Microenvironment Promotes Estrogen Receptor Activity Independent of Circulating Estradiol Levels. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-02-08 |
0.599 |
|
2011 |
Chen C, Rhodes M, Fabian C, Hursting S, deGraffenried L. P3-10-04: Halting Early Breast Cancer Progression with Omega-3 Ethyl Esters: Altering Tumor Microenvironment in 21T Series Cell Lines. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-10-04 |
0.482 |
|
2010 |
Salcedo R, Cavazos D, Hursting S, Angel RD, deGraffenried L, Beeram M. Abstract 5088: In vitro induction of a more aggressive prostate cancer phenotype by exposure to obese sera Cancer Research. 70: 5088-5088. DOI: 10.1158/1538-7445.Am10-5088 |
0.545 |
|
2010 |
Chen C, Fabian C, Hursting S, deGraffenried L. Abstract P1-06-01: Omega-3 Fatty Acids for Chemoprevention: NF-Kb as a Molecular Target in Both Pre and Post Menopausal High-Risk Breast Cancer Models Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P1-06-01 |
0.544 |
|
2009 |
DeAngel R, Tolstykh O, Nameer K, Jayarajan R, Perkins S, Tekmal R, DeGraffenried L, Hursting S. Effects of obesity on anastrozole response in a mouse model of postmenopausal breast cancer. Cancer Research. 69: 1146. DOI: 10.1158/0008-5472.Sabcs-1146 |
0.532 |
|
2009 |
Angel RD, Tekmal R, Perkins S, deGraffenried L, Hursting S. mTOR Inhibition and Diet Induced Obesity in a Mouse Model of Postmenopausal Breast Cancer. Cancer Research. 69: 5077-5077. DOI: 10.1158/0008-5472.Sabcs-09-5077 |
0.577 |
|
2009 |
Chen C, Gasperi MD, Salcedo R, Cavazos D, deGraffenried L. Evaluation of the Phytochemical Anethole as an Anti-Tumor Agent in MCF-7 Cells. Cancer Research. 69: 3100-3100. DOI: 10.1158/0008-5472.Sabcs-09-3100 |
0.468 |
|
2009 |
Gasperi MD, Cavazos D, deGraffenried L. Curcumin Modulates Tamoxifen Response in Resistant Breast Cancer Cells. Cancer Research. 69: 3098-3098. DOI: 10.1158/0008-5472.Sabcs-09-3098 |
0.477 |
|
2008 |
Troyer DA, Tang Y, Bedolla R, Adhvaryu SG, Thompson IM, Abboud-Werner S, Sun LZ, Friedrichs WE, DeGraffenried L. Characterization of PacMetUTI, a recently isolated human prostate cancer cell line The Prostate. 68: 883-892. PMID 18361412 DOI: 10.1002/Pros.20758 |
0.405 |
|
2004 |
deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8059-67. PMID 15585641 DOI: 10.1158/1078-0432.CCR-04-0035 |
0.371 |
|
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