Fred F. Kadlubar - Publications

Affiliations: 
University of Arkansas for Medical Sciences, United States 
Area:
Molecular Biology, Oncology

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Zhang X, Huang M, Wu X, Kadlubar S, Lin J, Yu X, Fan C, Ning B, Kadlubar FF. GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer. Pharmacogenomics and Personalized Medicine. 6: 9-17. PMID 23526580 DOI: 10.2147/Pgpm.S35949  0.354
2010 Yu X, Dhakal IB, Beggs M, Edavana VK, Williams S, Zhang X, Mercer K, Ning B, Lang NP, Kadlubar FF, Kadlubar S. Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 391-403. PMID 20881232 DOI: 10.1093/Toxsci/Kfq296  0.361
2010 Bessette EE, Spivack SD, Goodenough AK, Wang T, Pinto S, Kadlubar FF, Turesky RJ. Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry. Chemical Research in Toxicology. 23: 1234-44. PMID 20443584 DOI: 10.1021/Tx100098F  0.319
2010 Zhang J, Dhakal IB, Lang NP, Kadlubar FF. Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk. Cancer Causes & Control : Ccc. 21: 1437-44. PMID 20431935 DOI: 10.1007/S10552-010-9571-0  0.317
2010 Zhang J, Dhakal IB, Greene G, Lang NP, Kadlubar FF. Polymorphisms in hOGG1 and XRCC1 and risk of prostate cancer: effects modified by plasma antioxidants. Urology. 75: 779-85. PMID 19914697 DOI: 10.1016/J.Urology.2009.08.063  0.357
2010 Zhang J, Dhakal I, Greene G, Lang N, Kadlubar F. Abstract B123: Sequence variants in inflammatory genes, plasma antioxidants, and prostate cancer risk Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B123  0.377
2010 Zhang X, Kadlubar S, Mercer K, Yu X, Dhakal I, Beggs M, Caldwell D, Edavana VK, Williams S, Kadlubar FF. Abstract LB-105: Single nucleotide polymorphisms (SNPs) in the CYP19A1 gene are strongly associated with CYP1A2 expression: First evidence for epistasis in the CYP superfamily Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-105  0.377
2010 Yu X, Beggs ML, Dhakal IB, Zhang X, Edavana VK, Williams S, Mercer KE, Kadlubar FF, Kadlubar S. Abstract 916: Functional significance of sulfotransferase 1A1 polymorphisms in the 3’ untranslated region in determination of enzymatic activity Cancer Research. 70: 916-916. DOI: 10.1158/1538-7445.Am10-916  0.365
2010 Zhang X, Huang M, Wu X, Kadlubar S, Yu X, Caldwell D, Lin J, Ning B, Kadlubar FF. Abstract 885:GSTM1CNV and promoter SNPs are associated with REC/SPT and survival after Retinoid Acid treatment for head and neck cancer Cancer Research. 70: 885-885. DOI: 10.1158/1538-7445.Am10-885  0.339
2010 Edavana VK, Williams S, Beggs ML, Mercer K, Yu X, Zhang X, Caldwell DB, Kadlubar F, Kadlubar S. Abstract 2619: Sulfation of toremifene: Individual variability, isoform specificity, and contribution to toremifene pharmacogenomics Cancer Research. 70: 2619-2619. DOI: 10.1158/1538-7445.Am10-2619  0.409
2010 Zhang J, Zhang X, Dhakal I, Gross M, Lang N, Kadlubar F, Anderson K. Abstract 1861: Polymorphisms in antioxidant defense and DNA repair genes, dietary intake of antioxidants, and risk of pancreatic cancer Cancer Research. 70: 1861-1861. DOI: 10.1158/1538-7445.Am10-1861  0.424
2009 Zhang J, Dhakal IB, Gross MD, Lang NP, Kadlubar FF, Harnack LJ, Anderson KE. Physical activity, diet, and pancreatic cancer: a population-based, case-control study in Minnesota. Nutrition and Cancer. 61: 457-65. PMID 19838917 DOI: 10.1080/01635580902718941  0.357
2008 Mizumachi T, Muskhelishvili L, Naito A, Furusawa J, Fan CY, Siegel ER, Kadlubar FF, Kumar U, Higuchi M. Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells. The Prostate. 68: 408-17. PMID 18196528 DOI: 10.1002/Pros.20697  0.31
2008 Lin Z, Zhang X, Tuo J, Guo Y, Green B, Chan CC, Tan W, Huang Y, Ling W, Kadlubar FF, Lin D, Ning B. A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer. Human Mutation. 29: 113-22. PMID 17854076 DOI: 10.1002/Humu.20610  0.366
2008 Zhang J, Dhakal I, Gross M, Lang N, Kadlubar F, Kadlubar S, Anderson K. Abstract A95: Genetic variability in energy metabolism and pancreatic cancer risk: A population-based case-control study in Minnesota Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A95  0.403
2008 Gallagher CJ, Kadlubar FF, Muscat JE, Ambrosone CB, Lang NP, Lazarus P. The UGT2B17 gene deletion polymorphism and risk of prostate cancer: A case-control study in Caucasians Cancer Detection and Prevention. 32: 186-187. DOI: 10.1016/J.Cdp.2008.08.005  0.347
2007 Gallagher CJ, Kadlubar FF, Muscat JE, Ambrosone CB, Lang NP, Lazarus P. The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians. Cancer Detection and Prevention. 31: 310-5. PMID 17935910 DOI: 10.1016/J.Cdp.2007.07.005  0.39
2007 Zhang J, Dhakal I, Stone A, Ning B, Greene G, Lang NP, Kadlubar FF. Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas. Nutrition and Cancer. 59: 46-53. PMID 17927501 DOI: 10.1080/01635580701385900  0.336
2007 Liu R, Blower PE, Pham AN, Fang J, Dai Z, Wise C, Green B, Teitel CH, Ning B, Ling W, Lyn-Cook BD, Kadlubar FF, Sadée W, Huang Y. Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin. Molecular Pharmacology. 72: 1637-46. PMID 17875604 DOI: 10.1124/Mol.107.039644  0.31
2007 Kadlubar FF. Hormone-metabolizing genotypes: an alternate interpretation. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1911. PMID 17855714 DOI: 10.1158/1055-9965.Epi-07-0355  0.306
2007 Ambrosone CB, Abrams SM, Gorlewska-Roberts K, Kadlubar FF. Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells Archives of Biochemistry and Biophysics. 464: 169-175. PMID 17601487 DOI: 10.1016/J.Abb.2007.05.018  0.385
2007 Carreón T, Kadlubar FF, Ruder AM, Schulte PA, Hayes RB, Waters M, Grant DJ, Boissy R, Bell DA, Hemstreet GP, Yin S, Lemasters GK, Rothman N. Reply to the letter to the Editor: "N-Acetyltransferases and the susceptibility to benzidine-induced bladder carcinogenesis". International Journal of Cancer. 121: 1637-9; author reply. PMID 17583575 DOI: 10.1002/Ijc.22906  0.329
2007 Chen J, Kadlubar FF, Chen JZ. DNA supercoiling suppresses real-time PCR: a new approach to the quantification of mitochondrial DNA damage and repair. Nucleic Acids Research. 35: 1377-88. PMID 17284464 DOI: 10.1093/Nar/Gkm010  0.322
2007 Ward MH, Cross AJ, Divan H, Kulldorff M, Nowell-Kadlubar S, Kadlubar FF, Sinha R. Processed meat intake, CYP2A6 activity and risk of colorectal adenoma Carcinogenesis. 28: 1210-1216. PMID 17277235 DOI: 10.1093/Carcin/Bgm009  0.361
2006 Nakajima M, Itoh M, Sakai H, Fukami T, Katoh M, Yamazaki H, Kadlubar FF, Imaoka S, Funae Y, Yokoi T. CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl. International Journal of Cancer. 119: 2520-6. PMID 16988941 DOI: 10.1002/Ijc.22136  0.401
2006 Park J, Chen L, Ratnashinge L, Sellers TA, Tanner JP, Lee JH, Dossett N, Lang N, Kadlubar FF, Ambrosone CB, Zachariah B, Heysek RV, Patterson S, Pow-Sang J. Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 1473-8. PMID 16896035 DOI: 10.1158/1055-9965.Epi-06-0141  0.384
2006 Ahn J, Nowell S, McCann SE, Yu J, Carter L, Lang NP, Kadlubar FF, Ratnasinghe LD, Ambrosone CB. Associations between catalase phenotype and genotype: modification by epidemiologic factors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 1217-22. PMID 16775184 DOI: 10.1158/1055-9965.Epi-06-0104  0.757
2006 Tuo J, Ning B, Bojanowski CM, Lin ZN, Ross RJ, Reed GF, Shen D, Jiao X, Zhou M, Chew EY, Kadlubar FF, Chan CC. Synergic effect of polymorphisms in ERCC6 5' flanking region and complement factor H on age-related macular degeneration predisposition. Proceedings of the National Academy of Sciences of the United States of America. 103: 9256-61. PMID 16754848 DOI: 10.1073/Pnas.0603485103  0.333
2006 Jiang Z, Dragin N, Jorge-Nebert LF, Martin MV, Guengerich FP, Aklillu E, Ingelman-Sundberg M, Hammons GJ, Lyn-Cook BD, Kadlubar FF, Saldana SN, Sorter M, Vinks AA, Nassr N, von Richter O, et al. Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype. Pharmacogenetics and Genomics. 16: 359-67. PMID 16609368 DOI: 10.1097/01.Fpc.0000204994.99429.46  0.393
2006 Carreón T, Ruder AM, Schulte PA, Hayes RB, Rothman N, Waters M, Grant DJ, Boissy R, Bell DA, Kadlubar FF, Hemstreet GP, Yin S, LeMasters GK. NAT2 slow acetylation and bladder cancer in workers exposed to benzidine. International Journal of Cancer. 118: 161-8. PMID 16003747 DOI: 10.1002/Ijc.21308  0.406
2005 Coles BF, Kadlubar FF. Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease. Methods in Enzymology. 401: 9-42. PMID 16399377 DOI: 10.1016/S0076-6879(05)01002-5  0.38
2005 Anderson KE, Kadlubar FF, Kulldorff M, Harnack L, Gross M, Lang NP, Barber C, Rothman N, Sinha R. Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2261-5. PMID 16172241 DOI: 10.1158/1055-9965.Epi-04-0514  0.344
2005 Zhang X, Miao X, Tan W, Ning B, Liu Z, Hong Y, Song W, Guo Y, Zhang X, Shen Y, Qiang B, Kadlubar FF, Lin D. Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology. 129: 565-76. PMID 16083713 DOI: 10.1053/J.Gastro.2005.05.003  0.408
2005 Lin J, Kadlubar FF, Spitz MR, Zhao H, Wu X. A modified host cell reactivation assay to measure DNA repair capacity for removing 4-aminobiphenyl adducts: A pilot study of bladder cancer Cancer Epidemiology Biomarkers and Prevention. 14: 1832-1836. PMID 16030125 DOI: 10.1158/1055-9965.Epi-04-0902  0.372
2005 Ning B, Nowell S, Sweeney C, Ambrosone CB, Williams S, Miao X, Liang G, Lin D, Stone A, Ratnasinghe DL, Manjanatha M, Lang NP, Kadlubar FF. Common genetic polymorphisms in the 5'-flanking region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity. Pharmacogenetics and Genomics. 15: 465-73. PMID 15970794 DOI: 10.1097/01.Fpc.0000166823.74378.79  0.742
2005 Nowell SA, Ahn J, Rae JM, Scheys JO, Trovato A, Sweeney C, MacLeod SL, Kadlubar FF, Ambrosone CB. Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients. Breast Cancer Research and Treatment. 91: 249-58. PMID 15952058 DOI: 10.1007/S10549-004-7751-X  0.359
2005 Stone A, Ratnasinghe LD, Emerson GL, Modali R, Lehman T, Runnells G, Carroll A, Carter W, Barnhart S, Rasheed AA, Greene G, Johnson DE, Ambrosone CB, Kadlubar FF, Lang NP. CYP3A43 Pro(340)Ala polymorphism and prostate cancer risk in African Americans and Caucasians. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1257-61. PMID 15894682 DOI: 10.1158/1055-9965.Epi-04-0534  0.41
2005 Di Paolo OA, Teitel CH, Nowell S, Coles BF, Kadlubar FF. Expression of cytochromes P450 and glutathione S-transferases in human prostate, and the potential for activation of heterocyclic amine carcinogens via acetyl-coA-, PAPS- and ATP-dependent pathways. International Journal of Cancer. 117: 8-13. PMID 15880531 DOI: 10.1002/Ijc.21152  0.764
2005 Nowell S, Green B, Tang YM, Wiese R, Kadlubar FF. Examination of human tissue cytosols for expression of sulfotransferase isoform 1A2 (SULT1A2) using a SULT1A2-specific antibody. Molecular Pharmacology. 67: 394-9. PMID 15528404 DOI: 10.1124/Mol.104.006171  0.725
2004 Chen JZ, Kadlubar FF. Mitochondrial mutagenesis and oxidative stress in human prostate cancer. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews. 22: 1-12. PMID 15845219 DOI: 10.1081/Gnc-120037931  0.305
2004 Gorlewska-Roberts KM, Teitel CH, Lay JO, Roberts DW, Kadlubar FF. Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines. Chemical Research in Toxicology. 17: 1659-66. PMID 15606142 DOI: 10.1021/Tx049787N  0.377
2004 Huber WW, Teitel CH, Coles BF, King RS, Wiese FW, Kaderlik KR, Casciano DA, Shaddock JG, Mulder GJ, Ilett KF, Kadlubar FF. Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities. Environmental and Molecular Mutagenesis. 44: 265-76. PMID 15468054 DOI: 10.1002/Em.20052  0.364
2004 Yang M, Coles BF, Caporaso NE, Choi Y, Lang NP, Kadlubar FF. Lack of association between Caucasian lung cancer risk and O6-methylguanine-DNA methyltransferase-codon 178 genetic polymorphism. Lung Cancer (Amsterdam, Netherlands). 44: 281-6. PMID 15140540 DOI: 10.1016/J.Lungcan.2003.12.003  0.417
2004 Ning B, Wang C, Morel F, Nowell S, Ratnasinghe DL, Carter W, Kadlubar FF, Coles B. Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form. Pharmacogenetics. 14: 35-44. PMID 15128049 DOI: 10.1097/00008571-200401000-00004  0.757
2004 Kim D, Kadlubar FF, Teitel CH, Guengerich FP. Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines. Chemical Research in Toxicology. 17: 529-36. PMID 15089095 DOI: 10.1021/Tx034267Y  0.324
2004 Nowell S, Ratnasinghe DL, Ambrosone CB, Williams S, Teague-Ross T, Trimble L, Runnels G, Carrol A, Green B, Stone A, Johnson D, Greene G, Kadlubar FF, Lang NP. Association of SULT1A1 phenotype and genotype with prostate cancer risk in African-Americans and Caucasians. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 270-6. PMID 14973106 DOI: 10.1158/1055-9965.Epi-03-0047  0.761
2003 Amirimani B, Ning B, Deitz AC, Weber BL, Kadlubar FF, Rebbeck TR. Increased Transcriptional Activity of the CYP3A4* 1B Promoter Variant Environmental and Molecular Mutagenesis. 42: 299-305. PMID 14673875 DOI: 10.1002/Em.10199  0.363
2003 Coles BF, Kadlubar FF. Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs? Biofactors (Oxford, England). 17: 115-30. PMID 12897434 DOI: 10.1002/Biof.5520170112  0.411
2003 Faraglia B, Chen SY, Gammon MD, Zhang Y, Teitelbaum SL, Neugut AI, Ahsan H, Garbowski GC, Hibshoosh H, Lin D, Kadlubar FF, Santella RM. Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke. Carcinogenesis. 24: 719-25. PMID 12727801 DOI: 10.1093/Carcin/Bgg013  0.395
2003 Xia Q, Chou MW, Kadlubar FF, Chan PC, Fu PP. Human liver microsomal metabolism and DNA adduct formation of the tumorigenic pyrrolizidine alkaloid, riddelliine. Chemical Research in Toxicology. 16: 66-73. PMID 12693032 DOI: 10.1021/Tx025605I  0.376
2003 Kimura S, Kawabe M, Yu A, Morishima H, Fernandez-Salguero P, Hammons GJ, Ward JM, Kadlubar FF, Gonzalez FJ. Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2. Carcinogenesis. 24: 583-7. PMID 12663521 DOI: 10.1093/Carcin/24.3.583  0.34
2003 Lin DX, Thompson PA, Teitel C, Chen JS, Kadlubar FF. Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation. Mutation Research. 523: 193-200. PMID 12628517 DOI: 10.1016/S0027-5107(02)00335-4  0.4
2003 Sweeney C, Ambrosone CB, Joseph L, Stone A, Hutchins LF, Kadlubar FF, Coles BF. Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment International Journal of Cancer. 103: 810-814. PMID 12516103 DOI: 10.1002/Ijc.10896  0.358
2002 Sweeney C, Coles BF, Nowell S, Lang NP, Kadlubar FF. Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer. Toxicology. 181: 83-7. PMID 12505289 DOI: 10.1016/S0300-483X(02)00259-7  0.78
2002 Nowell S, Sweeney C, Winters M, Stone A, Lang NP, Hutchins LF, Kadlubar FF, Ambrosone CB. Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy. Journal of the National Cancer Institute. 94: 1635-40. PMID 12419790 DOI: 10.1093/Jnci/94.21.1635  0.751
2002 Yang M, Coles BF, Delongchamp R, Lang NP, Kadlubar FF. Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue. Lung Cancer (Amsterdam, Netherlands). 38: 15-21. PMID 12367788 DOI: 10.1016/S0169-5002(02)00150-2  0.387
2002 Anderson KE, Sinha R, Kulldorff M, Gross M, Lang NP, Barber C, Harnack L, DiMagno E, Bliss R, Kadlubar FF. Meat intake and cooking techniques: associations with pancreatic cancer. Mutation Research. 506: 225-31. PMID 12351162 DOI: 10.1016/S0027-5107(02)00169-0  0.339
2002 Nowell S, Coles B, Sinha R, MacLeod S, Luke Ratnasinghe D, Stotts C, Kadlubar FF, Ambrosone CB, Lang NP. Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk. Mutation Research. 506: 175-85. PMID 12351157 DOI: 10.1016/S0027-5107(02)00164-1  0.749
2002 Wu X, Zhao H, Amos CI, Shete S, Makan N, Hong WK, Kadlubar FF, Spitz MR. p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity. Journal of the National Cancer Institute. 94: 681-90. PMID 11983757 DOI: 10.1093/Jnci/94.9.681  0.381
2002 Nowell S, Sweeney C, Hammons G, Kadlubar FF, Lang NP. CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 11: 377-83. PMID 11927498  0.751
2002 Gorlewska-Roberts K, Green B, Fares M, Ambrosone CB, Kadlubar FF. Carcinogen-DNA adducts in human breast epithelial cells Environmental and Molecular Mutagenesis. 39: 184-192. PMID 11921188 DOI: 10.1002/Em.10060  0.377
2002 Thompson PA, DeMarini DM, Kadlubar FF, McClure GY, Brooks LR, Green BL, Fares MY, Stone A, Josephy PD, Ambrosone CB. Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells. Environmental and Molecular Mutagenesis. 39: 134-42. PMID 11921181 DOI: 10.1002/Em.10067  0.319
2002 Ishibe N, Sinha R, Hein DW, Kulldorff M, Strickland P, Fretland AJ, Chow WH, Kadlubar FF, Lang NP, Rothman N. Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics. 12: 145-50. PMID 11875368 DOI: 10.1097/00008571-200203000-00008  0.402
2001 Coles BF, Morel F, Rauch C, Huber WW, Yang M, Teitel CH, Green B, Lang NP, Kadlubar FF. Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression. Pharmacogenetics. 11: 663-669. PMID 11692074 DOI: 10.1097/00008571-200111000-00004  0.338
2001 Kadlubar FF. Concluding remarks: symposium on Genetic Susceptibility to Environmental Toxicants. Mutation Research. 482: 111-113. PMID 11535255 DOI: 10.1016/S0027-5107(01)00216-0  0.31
2001 Schoket B, Papp G, Lévay K, Mracková G, Kadlubar FF, Vincze I. Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure. Mutation Research. 482: 57-69. PMID 11535249 DOI: 10.1016/S0027-5107(01)00210-X  0.416
2001 Coles B, Nowell SA, MacLeod SL, Sweeney C, Lang NP, Kadlubar FF. The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk. Mutation Research. 482: 3-10. PMID 11535243 DOI: 10.1016/S0027-5107(01)00187-7  0.475
2001 Hammons GJ, Yan-Sanders Y, Jin B, Blann E, Kadlubar FF, Lyn-Cook BD. Specific site methylation in the 5'-flanking region of CYP1A2 interindividual differences in human livers. Life Sciences. 69: 839-45. PMID 11487095 DOI: 10.1016/S0024-3205(01)01175-4  0.349
2001 Tan W, Chen GF, Xing DY, Song CY, Kadlubar FF, Lin DX. Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. International Journal of Cancer. 95: 96-101. PMID 11241319 DOI: 10.1002/1097-0215(20010320)95:2<96::Aid-Ijc1017>3.0.Co;2-2  0.393
2001 Wiese FW, Thompson PA, Kadlubar FF. Carcinogen substrate specificity of human COX-1 and COX-2. Carcinogenesis. 22: 5-10. PMID 11159734 DOI: 10.1093/Carcin/22.1.5  0.379
2001 Muskhelishvili L, Thompson PA, Kusewitt DF, Wang C, Kadlubar FF. In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. Journal of Histochemistry and Cytochemistry. 49: 229-236. PMID 11156691 DOI: 10.1177/002215540104900210  0.333
2000 Tang YM, Green BL, Chen GF, Thompson PA, Lang NP, Shinde A, Lin DX, Tan W, Lyn-Cook BD, Hammons GJ, Kadlubar FF. Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls. Pharmacogenetics. 10: 761-6. PMID 11221602 DOI: 10.1097/00008571-200012000-00001  0.44
2000 Nowell S, Ambrosone CB, Ozawa S, MacLeod SL, Mrackova G, Williams S, Plaxco J, Kadlubar FF, Lang NP. Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol Pharmacogenetics. 10: 789-797. PMID 11191883 DOI: 10.1097/00008571-200012000-00004  0.768
2000 MacLeod SL, Nowell S, Massengill J, Jazieh A, McClure G, Plaxco J, Kadlubar FF, Lan NP. Cancer therapy and polymorphisms of cytochromes P450. Clinical Chemistry and Laboratory Medicine. 38: 883-7. PMID 11097344 DOI: 10.1515/Cclm.2000.128  0.748
2000 Coles B, Yang M, Lang NP, Kadlubar FF. Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide. Cancer Letters. 156: 167-175. PMID 10880766 DOI: 10.1016/S0304-3835(00)00458-4  0.386
2000 Fu P, Von Tungeln LS, Hammons GJ, McMahon G, Wogan G, Flammang TJ, Kadlubar FF. Metabolic activation capacity of neonatal mice in relation to the neonatal mouse tumorigenicity bioassay Drug Metabolism Reviews. 32: 241-266. PMID 10774778 DOI: 10.1081/Dmr-100100575  0.347
2000 Poirier LA, Doerge DR, Gaylor DW, Miller MA, Lorentzen RJ, Casciano DA, Kadlubar FF, Schwetz BA. An FDA review of sulfamethazine toxicity. Regulatory Toxicology and Pharmacology : Rtp. 30: 217-22. PMID 10620471 DOI: 10.1006/Rtph.1999.1348  0.302
2000 King RS, Teitel CH, Kadlubar FF. In vitro bioactivation of N-hydroxy-2-amino-α-carboline Carcinogenesis. 21: 1347-1354. DOI: 10.1093/Carcin/21.7.1347  0.329
2000 Agus C, Ilett KF, Kadlubar FF, Minchin RF. Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline Carcinogenesis. 21: 1213-1219. DOI: 10.1093/Carcin/21.6.1213  0.412
1999 Hammons GJ, Yan Y, Lopatina NG, Jin B, Wise C, Blann EB, Poirier LA, Kadlubar FF, Lyn-Cook BD. Increased expression of hepatic DNA methyltransferase in smokers. Cell Biology and Toxicology. 15: 389-94. PMID 10811534 DOI: 10.1023/A:1007658000971  0.378
1999 King RS, Teitel CH, Shaddock JG, Casciano DA, Kadlubar FF. Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative Cancer Letters. 143: 167-171. PMID 10503898 DOI: 10.1016/S0304-3835(99)00119-6  0.345
1999 Kimura S, Kawabe M, Ward JM, Morishima H, Kadlubar FF, Hammons GJ, Fernandez-Salguero P, Gonzalez FJ. CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice. Carcinogenesis. 20: 1825-1830. PMID 10469630 DOI: 10.1093/Carcin/20.9.1825  0.399
1999 Ozawa S, Shimizu M, Katoh T, Miyajima A, Ohno Y, Matsumoto Y, Fukuoka M, Tang YM, Lang NP, Kadlubar FF. Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A3*1 (213Arg) and ST1A3*2 (213His), Both of Which Exist in Japanese as Well as Caucasians Journal of Biochemistry. 126: 271-277. PMID 10423517 DOI: 10.1093/Oxfordjournals.Jbchem.A022445  0.36
1999 Nowell SA, Massengill JS, Williams S, Radominska-Pandya A, Tephly TR, Cheng Z, Strassburg CP, Tukey RH, MacLeod SL, Lang NP, Kadlubar FF. Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved. Carcinogenesis. 20: 1107-14. PMID 10357796 DOI: 10.1093/Carcin/20.6.1107  0.414
1999 Ozawa S, Schoket B, McDaniel LP, Tang YM, Ambrosone CB, Kostic S, Vincze I, Kadlubar FF. Analyses of bronchial bulky DNA adduct levels and CYP2C9, GSTP1 and NQO1 genotypes in a Hungarian study population with pulmonary diseases Carcinogenesis. 20: 991-995. PMID 10357778 DOI: 10.1093/Carcin/20.6.991  0.432
1999 Hammons GJ, Fletcher JV, Stepps KR, Smith EA, Balentine DA, Harbowy ME, Kadlubar FF. Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4-aminobiphenyl in human and rat liver microsomes. Nutrition and Cancer. 33: 46-52. PMID 10227043 DOI: 10.1080/01635589909514747  0.332
1999 Thompson PA, Seyedi F, Lang NP, MacLeod SL, Wogan GN, Anderson KE, Tang YM, Coles B, Kadlubar FF. Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype. Mutation Research. 424: 263-74. PMID 10064866 DOI: 10.1016/S0027-5107(99)00024-X  0.419
1999 Ariyoshi N, Nunoya K, Takahashi Y, Umetsu Y, Miyamoto M, Daigo S, Yokoi T, Kwon J, Kadlubar FF, Shinha R, Beaune P, Kimura K, Kamataki T. The Study On Cyp2A6 Genetic Polymorphism Drug Metabolism and Pharmacokinetics. 14: 100-101. DOI: 10.2133/Dmpk.14.Supplement_100  0.352
1998 Shirai T, Takahashi S, Cui L, Yamada Y, Tada M, Kadlubar FF, Ito N. Use of polyclonal antibodies against carcinogen–DNA adducts in analysis of carcinogenesis Toxicology Letters. 102: 441-446. PMID 10022293 DOI: 10.1016/S0378-4274(98)00366-X  0.323
1998 Kadlubar FF, Anderson KE, Häussermann S, Lang NP, Barone GW, Thompson PA, MacLeod SL, Chou MW, Mikhailova M, Plastaras J, Marnett LJ, Nair J, Velic I, Bartsch H. Comparison of DNA adduct levels associated with oxidative stress in human pancreas. Mutation Research. 405: 125-33. PMID 9748537 DOI: 10.1016/S0027-5107(98)00129-8  0.384
1998 Ozawa S, Tang YM, Yamazoe Y, Kato R, Lang NP, Kadlubar FF. Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines. Chemico-Biological Interactions. 109: 237-248. PMID 9566748 DOI: 10.1016/S0009-2797(97)00135-X  0.384
1998 Fu PP, Von Tungeln LS, Yi P, Xia Q, Casciano AA, Flammang TJ, Kadlubar FF. Neonatal Mouse Tumorigenicity Bioassay Drug Information Journal. 32: 711-728. DOI: 10.1177/009286159803200311  0.343
1997 Frame LT, Gatlin TL, Kadlubar FF, Lang NP. Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer. Environmental Toxicology and Pharmacology. 4: 277-281. PMID 21781833 DOI: 10.1016/S1382-6689(97)10023-0  0.431
1997 Flammang TJ, Tungeln LSV, Kadlubar FF, Fu PP. Neonatal mouse assay for tumorigenicity: alternative to the chronic rodent bioassay. Regulatory Toxicology and Pharmacology. 26: 230-240. PMID 9356286 DOI: 10.1006/Rtph.1997.1125  0.308
1997 Culp SJ, Roberts DW, Talaska G, Lang NP, Fu PP, Lay JO, Teitel CH, Snawder JE, Von Tungeln LS, Kadlubar FF. Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation. Mutation Research. 378: 97-112. PMID 9288889 DOI: 10.1016/S0027-5107(97)00101-2  0.386
1997 MacLeod S, Sinha R, Kadlubar FF, Lang NP. Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2 Mutation Research. 376: 135-142. PMID 9202749 DOI: 10.1016/S0027-5107(97)00036-5  0.385
1997 Huber WW, McDaniel LP, Kaderlik KR, Teitel CH, Lang NP, Kadlubar FF. Chemoprotection against the formation of colon DNA adducts from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat Mutation Research. 376: 115-122. PMID 9202746 DOI: 10.1016/S0027-5107(97)00033-X  0.367
1997 Anderson KE, Hammons GJ, Kadlubar FF, Potter JD, Kaderlik KR, Ilett KF, Minchin RF, Teitel CH, Chou HC, Martin MV, Guengerich FP, Barone GW, Lang NP, Peterson LA. Metabolic activation of aromatic amines by human pancreas. Carcinogenesis. 18: 1085-92. PMID 9163700 DOI: 10.1093/Carcin/18.5.1085  0.408
1997 Hammons GJ, Milton D, Stepps K, Guengerich FP, Tukey RH, Kadlubar FF. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes. Carcinogenesis. 18: 851-4. PMID 9111224 DOI: 10.1093/Carcin/18.4.851  0.355
1997 Kadlubar FF. O I.2 Metabolic activation and detoxification of carcinogens in relation to DNA adduct levels and cancer susceptibility in humans Mutation Research. 379. DOI: 10.1016/S0027-5107(97)82614-0  0.388
1996 Alexandrov K, Rojas M, Kadlubar FF, Lang NP, Bartsch H. Evidence of anti-benzo[a]pyrene diolepoxide-DNA adduct formation in human colon mucosa. Carcinogenesis. 17: 2081-2083. PMID 8824539 DOI: 10.1093/Carcin/17.9.2081  0.382
1996 Butcher NJ, Minchin RF, Kadlubar FF, Ilett KF. Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro. Carcinogenesis. 17: 889-92. PMID 8625507 DOI: 10.1093/Carcin/17.4.889  0.365
1995 Kadlubar FF, Badawi AF. Genetic susceptibility and carcinogen-DNA adduct formation in human urinary bladder carcinogenesis. Toxicology Letters. 627-32. PMID 8597119 DOI: 10.1016/0378-4274(95)03507-9  0.488
1995 Sinha R, Rothman N, Mark SD, Murray S, Brown ED, Levander OA, Davies DS, Lang NP, Kadlubar FF, Hoover RN. Lower levels of urinary 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) in humans with higher CYP1A2 activity Carcinogenesis. 16: 2859-2861. PMID 7586210 DOI: 10.1093/Carcin/16.11.2859  0.382
1995 Kaderlik KR, Kadlubar FF. Metabolic polymorphisms and carcinogen-DNA adduct formation in human populations. Pharmacogenetics. 5. PMID 7581479 DOI: 10.1097/00008571-199512001-00011  0.449
1995 Al-Atrash J, Zhang YJ, Lin D, Kadlubar FF, Santella RM. Quantitative immunohistochemical analysis of 4-aminobiphenyl-DNA in cultured cells and mice: Comparison to gas chromatography/mass spectroscopy analysis Chemical Research in Toxicology. 8: 747-752. PMID 7548758 DOI: 10.1021/Tx00047A015  0.349
1994 Ilett KF, Ingram DM, Carpenter DS, Teitel CH, Lang NP, Kadlubar FF, Minchin RF. Expression of monomorphic and polymorphic N-acetyltransferases in human colon Biochemical Pharmacology. 47: 914-917. PMID 8135868 DOI: 10.1016/0006-2952(94)90493-6  0.391
1994 Kadlubar FF. Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans. Drug Metabolism Reviews. 26: 37-46. PMID 8082575 DOI: 10.3109/03602539409029783  0.331
1994 Kaderlik KR, Mulder GJ, Shaddock JG, Casciano DA, Teitel CH, Kadlubar FF. Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes. Carcinogenesis. 15: 1711-6. PMID 8055653 DOI: 10.1093/Carcin/15.8.1711  0.401
1994 Kaderlik KR, Minchin RF, Mulder GJ, Ilett KF, Daugaard-Jenson M, Teitel CH, Kadlubar FF. Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues. Carcinogenesis. 15: 1703-9. PMID 8055652 DOI: 10.1093/Carcin/15.8.1703  0.412
1994 Kaderlik KR, Mulder GJ, Turesky RJ, Lang NP, Teitel CH, Chiarelli MP, Kadlubar FF. Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes. Carcinogenesis. 15: 1695-701. PMID 8055651 DOI: 10.1093/Carcin/15.8.1695  0.364
1994 Sotomayor RE, Sega GA, Kadlubar F. Induction of DNA damage by urethane in mouse testes: DNA binding and unscheduled DNA synthesis. Environmental and Molecular Mutagenesis. 24: 68-74. PMID 8050418 DOI: 10.1002/Em.2850240109  0.329
1994 Vineis P, Bartsch H, Caporaso N, Harrington AM, Kadlubar FF, Landi MT, Malaveille C, Shields PG, Skipper P, Talaska G, Tannenbaum SR. Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogenesis Nature. 369: 154-156. PMID 7909916 DOI: 10.1038/369154A0  0.383
1994 Ozawa S, Chou H, Kadlubar FF, Nagata K, Yamazoe Y, Kato R. Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b] pyridine by cDNA-expressed human and rat arylsulfotransferases. Japanese Journal of Cancer Research. 85: 1220-1228. PMID 7852185 DOI: 10.1111/J.1349-7006.1994.Tb02933.X  0.396
1994 Friesen MD, Kaderlik K, Lin D, Garren L, Bartsch H, Lang NP, Kadlubar FF. Analysis of DNA Adducts of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Rat and Human Tissues by Alkaline Hydrolysis and Gas Chromatography/Electron Capture Mass Spectrometry: Validation by Comparison with 32P-Postlabeling Chemical Research in Toxicology. 7: 733-739. PMID 7696526 DOI: 10.1021/Tx00042A004  0.357
1994 Lin D, Lay JO, Bryant MS, Malaveille C, Friesen M, Bartsch H, Lang NP, Kadlubar FF. Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry. Environmental Health Perspectives. 102: 11-16. DOI: 10.2307/3432144  0.367
1993 Bartsch H, Malaveille C, Friesen M, Kadlubar FF, Vineis P. Black (air-cured) and blond (flue-cured) tobacco cancer risk IV: Molecular dosimetry studies implicate aromatic amines as bladder carcinogens European Journal of Cancer. 29: 1199-1207. PMID 8518034 DOI: 10.1016/S0959-8049(05)80315-6  0.314
1993 Ilett KF, Castleden WM, Vandongen YK, Stacey MC, Butler MA, Kadlubar FF. Acetylation phenotype and cytochrome P450IA2 phenotype are unlikely to be associated with peripheral arterial disease Clinical Pharmacology & Therapeutics. 54: 317-322. PMID 8375127 DOI: 10.1038/Clpt.1993.153  0.31
1993 Swenson DH, el-Bayoumy K, Shuie GH, Hecht SS, Fiala E, Kadlubar FF, Freeman JP. Synthesis of N-(purin-8-yl)arylamines. Chemical Research in Toxicology. 6: 480-5. PMID 8374045 DOI: 10.1021/Tx00034A014  0.351
1993 Talaska G, Schamer M, Skipper P, Tannenbaum S, Caporaso N, Kadlubar F, Bartsch H, Vineis P. Carcinogen-DNA adducts in exfoliated urothelial cells: techniques for noninvasive human monitoring. Environmental Health Perspectives. 99: 289-91. PMID 8319646 DOI: 10.1289/Ehp.9399289  0.377
1993 Segerbäck D, Kaderlik KR, Talaska G, Dooley KL, Kadlubar FF. 32P-postlabelling analysis of DNA adducts of 4,4'-methylenebis(2-chloroaniline) in target and nontarget tissues in the dog and their implications for human risk assessment. Carcinogenesis. 14: 2143-7. PMID 8222068 DOI: 10.1093/Carcin/14.10.2143  0.401
1993 Bell DA, Taylor JA, Butler MA, Stephens EA, Wiest J, Brubaker LH, Kadlubar FF, Lucier GW. Short communication: Genotype/phenotype discordance for human arylamine n-acetyltransferase (nat2) reveals a new slow-acetylator allele common in african-americans Carcinogenesis. 14: 1689-1692. PMID 8102597 DOI: 10.1093/Carcin/14.8.1689  0.357
1993 Ketterer B, Harris JM, Talaska G, Meyer DJ, Pemble SE, Taylor JB, Lang NP, Kadlubar FF. The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer. Environmental Health Perspectives. 98: 87-94. PMID 1486868 DOI: 10.1289/Ehp.929887  0.389
1992 Cho BP, Kadlubar FF, Culp SJ, Evans FE. 15N nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanosine, and other C8-substituted guanine nucleosides. Chemical Research in Toxicology. 3: 445-52. PMID 2133096 DOI: 10.1021/Tx00017A010  0.323
1992 Minchin RF, Reeves PT, Teitel CH, Mcmanus ME, Mojarrabi B, Ilett K, Kadlubar FF. N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells Biochemical and Biophysical Research Communications. 185: 839-844. PMID 1627140 DOI: 10.1016/0006-291X(92)91703-S  0.38
1992 Groopman JD, Skipper PL, Donahue PR, Trudel LJ, Wildschutte M, Kadlubar FF, Tannenbaum SR. Monoclonal antibodies and rabbit antisera recognizing 4-aminobiphenyl-DNA adducts and application to immunoaffinity chromatography Carcinogenesis. 13: 917-922. PMID 1600611 DOI: 10.1093/Carcin/13.6.917  0.326
1992 Dooley KL, Tungeln LSV, Bucci T, Fu PP, Kadlubar FF. Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates,Glu-P-1,IQ,PhIP,and MeIQx in the neonatal B6C3F1 male mouse Cancer Letters. 62: 205-209. PMID 1596864 DOI: 10.1016/0304-3835(92)90097-F  0.312
1992 Minchin RF, Ilett KF, Teitel CH, Reeves PT, Kadlubar FF. Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts. Carcinogenesis. 13: 663-667. PMID 1576718 DOI: 10.1093/Carcin/13.4.663  0.366
1992 Kadlubar FF, Butler MA, Kaderlik KR, Chou H, Lang NP. Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis. Environmental Health Perspectives. 98: 69-74. PMID 1486865 DOI: 10.1289/Ehp.929869  0.364
1992 Gaylor DW, Kadlubar FF, Beland FA. Application of biomarkers to risk assessment. Environmental Health Perspectives. 98: 139-141. PMID 1486842 DOI: 10.1289/Ehp.9298139  0.308
1992 Kaderlik RK, Lin D-, Lang NP, Kadlubar FF. Advantages and limitations of laboratory methods for measurement of carcinogen-DNA adducts for epidemiological studies. Toxicology Letters. 469-75. PMID 1471199 DOI: 10.1016/0378-4274(92)90221-5  0.365
1992 Lin D, Kaderlik KR, Turesky RJ, Miller DW, Lay JO, Kadlubar FF. Identification of N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA. Chemical Research in Toxicology. 5: 691-697. PMID 1446011 DOI: 10.1021/Tx00029A016  0.39
1992 Kadlubar FF. Detection of human DNA-carcinogen adducts. Nature. 360: 189-189. PMID 1436097 DOI: 10.1038/360189A0  0.369
1992 Segerbäck D, Kadlubar FF. Characterization of 4,4'-methylenebis(2-chloroaniline)--DNA adducts formed in vivo and in vitro. Carcinogenesis. 13: 1587-1592. PMID 1394844 DOI: 10.1093/Carcin/13.9.1587  0.401
1992 Turesky RJ, Rossi SC, Welti DH, Lay JO, Kadlubar FF. Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine. Chemical Research in Toxicology. 5: 479-490. PMID 1391614 DOI: 10.1021/Tx00028A005  0.35
1992 Butler MA, Lang NP, Young JF, Caporaso NE, Vineis P, Hayes RB, Teitel CH, Massengill JP, Lawsen MF, Kadlubar FF. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. Pharmacogenetics. 2: 116-27. PMID 1306111 DOI: 10.1097/00008571-199206000-00003  0.433
1992 Gaylor DW, Kadlubar FF, Beland FA. Commentary: Application of Biomarkers to Risk Assessment Environmental Health Perspectives. 98: 139. DOI: 10.2307/3431260  0.374
1992 Kadlubar FF, Guengerich FP. Inducibility of human cytochromes P-450 primarily involved in the activation of chemical carcinogens Chemosphere. 25: 201-204. DOI: 10.1016/0045-6535(92)90513-Q  0.388
1991 Bartsch H, Caporaso N, Coda M, Kadlubar F, Malaveille C, Skipper P, Talaska G, Tannenbaum SR, Vineis P. Carcinogen hemoglobin adducts, urinary mutagenicity, and metabolic phenotype in active and passive cigarette smokers. Journal of the National Cancer Institute. 82: 1826-31. PMID 2250298 DOI: 10.1093/Jnci/82.23.1826  0.31
1991 Talaska G, al-Juburi AZ, Kadlubar FF. Smoking related carcinogen-DNA adducts in biopsy samples of human urinary bladder: identification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl as a major adduct. Proceedings of the National Academy of Sciences of the United States of America. 88: 5350-4. PMID 2052611 DOI: 10.1073/Pnas.88.12.5350  0.369
1991 Peluso M, Castegnaro M, Malaveille C, Friesen M, Garren L, Hautefeuille A, Vineis P, Kadlubar F, Bartsch H. 32Postabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phnylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent Carcinogenesis. 12: 713-717. PMID 2013135 DOI: 10.1093/Carcin/12.4.713  0.354
1991 Yu SY, Heflich RH, Von Tungeln LS, el-Bayoumy K, Kadlubar FF, Fu PP. Comparative direct-acting mutagenicity of 1- and 2-nitropyrene: evidence for 2-nitropyrene mutagenesis by both guanine and adenine adducts. Mutation Research. 250: 145-52. PMID 1944329 DOI: 10.1016/0027-5107(91)90170-S  0.343
1991 Turesky RJ, Lang NP, Butler MA, Teitel CH, Kadlubar FF. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon Carcinogenesis. 12: 1839-1845. PMID 1934265 DOI: 10.1093/Carcin/12.10.1839  0.424
1991 Hemminki K, Szyfter K, Kadlubar FF. Quantitation of the 32P-postlabeling reaction using cyclic N1,N2 and C8 modified deoxyguanosine 3'-monophosphates as substrates. Chemico-Biological Interactions. 77: 51-61. PMID 1845762 DOI: 10.1016/0009-2797(91)90005-R  0.318
1991 Hammons GJ, Dooley KL, Kadlubar FF. 4-Aminobiphenyl-hemoglobin adduct formation as an index of in vivo N-oxidation by hepatic cytochrome P-450IA2. Chemical Research in Toxicology. 4: 144-147. PMID 1782342 DOI: 10.1021/Tx00020A003  0.312
1990 Lakshmi VM, Mattammal MB, Spry LA, Kadlubar FF, Zenser TV, Davis BB. Metabolism and disposition of benzindine in the dog Carcinogenesis. 11: 139-144. PMID 2403856 DOI: 10.1093/Carcin/11.1.139  0.376
1990 Peluso M, Castegnaro M, Malaveille C, Talaska G, Vineis P, Kadlubar F, Bartsch H. 32P-postlabelling analysis of DNA adducted with urinary mutagens from smokers of black tobacco. Carcinogenesis. 11: 1307-11. PMID 2387016 DOI: 10.1093/Carcin/11.8.1307  0.386
1990 Wohlleb JC, Hunter CF, Blass B, Kadlubar FF, Chu DZJ, Lang NP. Aromatic amine acetyltransferase as a marker for colorectal cancer: environmental and demographic associations. International Journal of Cancer. 46: 22-30. PMID 2365498 DOI: 10.1002/Ijc.2910460107  0.351
1990 Talaska G, Dooley KL, Kadlubar FF. Detection and characterization of carcinogen-DNA adducts in exfoliated urothelial cells from 4-aminobiphenyl-treated dogs by 32P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography. Carcinogenesis. 11: 639-46. PMID 2323002 DOI: 10.1093/Carcin/11.4.639  0.367
1990 Guengerich FP, Shimada T, Iwasaki M, Butler MA, Kadlubar FF. Activation of Carcinogens by Human Liver Cytochromes P-450 Basic Life Sciences. 53: 381-396. PMID 2282045 DOI: 10.1007/978-1-4613-0637-5_30  0.359
1990 Kadlubar FF, Fu PP, Jung H, Shaikh AU, Beland FA. The metabolic N-oxidation of carcinogenic arylamines in relation to nitrogen charge density and oxidation potential. Environmental Health Perspectives. 87: 233-236. PMID 2269230 DOI: 10.1289/Ehp.9087233  0.316
1990 Butler MA, Lang NP, Young JF, Talaska G, Massengill J, Teitel C, Kadlubar FF. Determination of Carcinogenic Arylamine N-Oxidation Phenotype in Humans by Analysis of Caffeine Urinary Metabolites Progress in Clinical and Biological Research. 318-318. DOI: 10.1007/978-1-4615-3800-4_30  0.414
1989 Butler MA, Iwasaki M, Guengerich FP, Kadlubar FF. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proceedings of the National Academy of Sciences of the United States of America. 86: 7696-700. PMID 2813353 DOI: 10.1073/Pnas.86.20.7696  0.389
1989 Wilson VL, Weston A, Manchester DK, Trivers GE, Roberts DW, Kadlubar FF, Montesano R, Willey JC, Mann DL, Harris CC. Alkyl and aryl carcinogen adducts detected in human peripheral lung Carcinogenesis. 10: 2149-2153. PMID 2805234 DOI: 10.1093/Carcin/10.11.2149  0.352
1989 Krauss RS, Angerman‐Stewart J, Eling TE, Dooley KL, Kadlubar FF. The formation of 2-aminofluorene-DNA adducts in vivo: evidence for peroxidase-mediated activation. Journal of Biochemical Toxicology. 4: 111-117. PMID 2593130 DOI: 10.1002/Jbt.2570040207  0.389
1989 Hammons GJ, Alworth WL, Hopkins NE, Guengerich FP, Kadlubar FF. 2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine. Chemical Research in Toxicology. 2: 367-74. PMID 2519725 DOI: 10.1021/Tx00012A003  0.331
1988 Flammang TJ, Yamazoe Y, Guengerich FP, Kadlubar FF. The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen N-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine N-acetyltransferase phenotype. Carcinogenesis. 8: 1967-70. PMID 3677322 DOI: 10.1093/Carcin/8.12.1967  0.409
1988 Dooley KL, Stavenuiter JFC, Westra JG, Kadlubar FF. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse Cancer Letters. 41: 99-103. PMID 3390806 DOI: 10.1016/0304-3835(88)90060-2  0.301
1988 Ziegler DM, Ansher SS, Nagata T, Kadlubar FF, Jakoby WB. N-methylation: potential mechanism for metabolic activation of carcinogenic primary arylamines. Proceedings of the National Academy of Sciences of the United States of America. 85: 2514-2517. PMID 3357879 DOI: 10.1073/Pnas.85.8.2514  0.35
1988 Delclos KB, el-Bayoumy K, Hecht SS, Walker RP, Kadlubar FF. Metabolism of the carcinogen [3H]6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite. Carcinogenesis. 9: 1875-84. PMID 3168165 DOI: 10.1093/Carcin/9.10.1875  0.334
1988 Yamazoe Y, Zenser TV, Miller DW, Kadlubar FF. Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine Carcinogenesis. 9: 1635-1641. PMID 3136947 DOI: 10.1093/Carcin/9.9.1635  0.379
1987 Tullis DL, Dooley KL, Miller DW, Baetcke KP, Kadlubar FF. Characterization and properties of the DNA adducts formed from N-methyl-4-aminoazobenzene in rats during a carcinogenic treatment regimen. Carcinogenesis. 8: 577-583. PMID 3829320 DOI: 10.1093/Carcin/8.4.577  0.383
1987 Delclos KB, Miller DW, Lay JO, Casciano DA, Walker RP, Fu PP, Kadlubar FF. Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts in isolated rat hepatocytes treated with 6-nitrochrysene and 6-aminochrysene. Carcinogenesis. 8: 1703-9. PMID 3664962 DOI: 10.1093/Carcin/8.11.1703  0.393
1987 Ni YC, Heflich RH, Kadlubar FF, Fu PP. Mutagenicity of nitrofurans in Salmonella typhimurium TA98, TA98NR and TA98/1,8-DNP6. Mutation Research. 192: 15-22. PMID 3309641 DOI: 10.1016/0165-7992(87)90120-5  0.304
1987 Lasko DD, Basu AK, Kadlubar FF, Evans FE, Lay JO, Essigmann JM. A probe for the mutagenic activity of the carcinogen 4-aminobiphenyl: synthesis and characterization of an M13mp10 genome containing the major carcinogen-DNA adduct at a unique site. Biochemistry. 26: 3072-81. PMID 3300770 DOI: 10.1021/Bi00385A019  0.311
1987 Coles B, Beale D, Miller D, Lay J, Kadlubar F, Aitken A, Ketterer B. The binding of an aminoazo dye carcinogen to a specific methionine residue in rat liver alcohol dehydrogenase in vivo. Chemico-Biological Interactions. 64: 181-192. PMID 3121196 DOI: 10.1016/0009-2797(87)90070-6  0.323
1986 Yamazoe Y, Roth RW, Kadlubar FF. Reactivity of benzidine diimine with DNA to form N-(deoxyguanosin-8-yl)-benzidine Carcinogenesis. 7: 179-182. PMID 3943140 DOI: 10.1093/Carcin/7.1.179  0.368
1986 Kadlubar FF, Yamazoe Y, Lang NP, Chu DZJ, Beland FA. Carcinogen-DNA adduct formation as a predictor of metabolic activation pathways and reactive intermediates in benzidine carcinogenesis. Advances in Experimental Medicine and Biology. 197: 537-549. PMID 3766280 DOI: 10.1007/978-1-4684-5134-4_51  0.394
1986 Lang NP, Chu DZJ, Hunter CF, Kendall DC, Flammang TJ, Kadlubar FF. Role of aromatic amine acetyltransferase in human colorectal cancer. Archives of Surgery. 121: 1259-1261. DOI: 10.1001/Archsurg.1986.01400110045007  0.393
1985 Beland FA, Kadlubar FF. Formation and persistence of arylamine DNA adducts in vivo. Environmental Health Perspectives. 62: 19-30. PMID 4085422 DOI: 10.1289/Ehp.856219  0.318
1985 Westra JG, Flammang TJ, Fullerton NF, Beland FA, Weis CC, Kadlubar FF. Formation of DNA adducts in vivo in rat liver and intestinal epithelium after administration of the carcinogen 3,2'-dimethyl-4-aminobiphenyl and its hydroxamic acid Carcinogenesis. 6: 37-44. PMID 4038474 DOI: 10.1093/Carcin/6.1.37  0.387
1985 Frederick CB, Weis CC, Flammang TJ, Martin CN, Kadlubar FF. Hepatic N-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine. Carcinogenesis. 6: 959-65. PMID 4017176 DOI: 10.1093/Carcin/6.7.959  0.348
1985 Yamazoe Y, Miller DW, Weis CC, Dooley KL, Zenser TV, Beland FA, Kadlubar FF. DNA adducts formed by ring-oxidation of the carcinogen 2-naphthylamine with prostaglandin H synthase in vitro and in the dog urothelium in vivo. Carcinogenesis. 6: 1379-1387. PMID 3928186 DOI: 10.1093/Carcin/6.9.1379  0.372
1984 Coles B, Ketterer B, Beland FA, Kadlubar FF. Glutathione conjugate formation in the detoxification of ultimate and proximate carcinogens of N-methyl-4-aminoazobenzene Carcinogenesis. 5: 917-920. PMID 6733853 DOI: 10.1093/Carcin/5.7.917  0.336
1984 Kadlubar FF, Beranek DT, Weis CC, Evans FE, Cox R, Irving CC. Characterization of the purine ring-opened 7-methylguanine and its presistence in rat bladder epithelial DNA after treatment with the carcinogen N-methylnitrosourea Carcinogenesis. 5: 587-592. PMID 6722978 DOI: 10.1093/Carcin/5.5.587  0.317
1984 Kennelly JC, Beland FA, Kadlubar FF, Martin CN. Binding of N-acetylbenzidine and N,N'-diacetylbenzidine to hepatic DNA of rat and hamster in vivo and in vitro. Carcinogenesis. 5: 407-12. PMID 6705145 DOI: 10.1093/Carcin/5.3.407  0.368
1983 Beranek DT, Weis CC, Evans FE, Chetsanga CJ, Kadlubar FF. Identification Of N5-Methyl-N5-Formyl-2,5,6-Triamino-4-Hydroxypyrimidine As A Major Adduct In Rat Liver Dna After Treatment With The Carcinogens, N,N-Dimethylnitrosamine Or 1,2-Dimethylhydrazine Biochemical and Biophysical Research Communications. 110: 625-631. PMID 6838542 DOI: 10.1016/0006-291X(83)91195-6  0.366
1983 Martin CN, Beland FA, Kennelly JC, Kadlubar FF. Binding of benzidine, N-acetylbenzidine, N, N'-diacetylbenzidine and Direct Blue 6 to rat liver DNA. Environmental Health Perspectives. 49: 101-6. PMID 6832087 DOI: 10.1289/Ehp.8349101  0.353
1983 Coles B, Srai SKS, Ketterer B, Waynforth B, Kadlubar FF. Identification of 4'-sulphonyloxy-N-(glutathion-S-methylene)-4-aminoazobenzene, a compound conjugated with both sulphate and glutathione, which is a major biliary metabolite of N,N-dimethyl-4-aminoazobenzene. Chemico-Biological Interactions. 43: 123-129. PMID 6402313 DOI: 10.1016/0009-2797(83)90091-1  0.333
1983 Beland FA, Beranek DT, Dooley KL, Heflich RH, Kadlubar FF. Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis. Environmental Health Perspectives. 49: 125-34. PMID 6339219 DOI: 10.1289/Ehp.8349125  0.394
1982 Mulder GJ, Unruh LE, Evans FE, Ketterer B, Kadlubar FF. Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene. Chemico-Biological Interactions. 39: 111-27. PMID 7060218 DOI: 10.1016/0009-2797(82)90010-2  0.329
1982 Fu PP, Heflich RH, Casciano DA, Huang AY, Trie WM, Kadlubar FF, Beland FA. Biologically active aromatic amines derived from carcinogenic polycyclic aromatic hydrocarbons: synthesis and mutagenicity of aminobenzo[a]pyrenes. Mutation Research. 94: 13-21. PMID 7048083 DOI: 10.1016/0027-5107(82)90164-6  0.328
1982 Fu PP, Chou MW, Yang SK, Beland FA, Kadlubar FF, Casciano DA, Heflich RH, Evans FE. Metabolism of the mutagenic environmental pollutant, 6-nitrobenzo[a]pyrene: metabolic activation via ring oxidation. Biochemical and Biophysical Research Communications. 105: 1037-43. PMID 7046751 DOI: 10.1016/0006-291X(82)91074-9  0.312
1982 Kadlubar FF, Frederick CB, Weis CC, Zenser TV. Prostaglandin endoperoxide synthetase-mediated metabolism of carcinogenic aromatic amines and their binding to DNA and protein. Biochemical and Biophysical Research Communications. 108: 253-8. PMID 6816227 DOI: 10.1016/0006-291X(82)91859-9  0.375
1982 Ketterer B, Srai SKS, Waynforth B, Tullis DL, Evans FE, Kadlubar FF. Formation of N-(glutathion-S-methylene)-4-aminoazobenzene following metabolic oxidation of the N-methyl group of the carcinogen, N-methyl-4-aminoazobenzene. Chemico-Biological Interactions. 38: 287-302. PMID 6800667 DOI: 10.1016/0009-2797(82)90059-X  0.356
1981 Frederick CB, Mays JB, Kadlubar FF. A chromatographic technique for the analysis of oxidized metabolites: application to carcinogenic N-hydroxyarylamines in urine. Analytical Biochemistry. 118: 120-5. PMID 7337206 DOI: 10.1016/0003-2697(81)90166-4  0.35
1981 Oldham JW, Kadlubar FF, Milo GE. Effect of pH on the neoplastic transformation of normal human skin fibroblasts by N-hydroxy-1-napthylamine and N-hydroxy-2-naphthylamine Carcinogenesis. 2: 937-940. PMID 7296774 DOI: 10.1093/Carcin/2.9.937  0.314
1981 Kadlubar FF, Anson JF, Dooley KL, Beland FA. Formation of urothelial and hepatic DNA adducts from the carcinogen 2-naphthylamine Carcinogenesis. 2: 467-470. PMID 7273326 DOI: 10.1093/Carcin/2.5.467  0.375
1980 Kadlubar FF, Unruh LE, Beland FA, Straub KM, Evans FE. In vitro reaction of the carcinogen, N-hydroxy-2-naphthylamine, with DNA at the C-8 and N2 atoms of guanine and at the N6 atom of adenine. Carcinogenesis. 1: 139-150. PMID 22282993 DOI: 10.1093/Carcin/1.2.139  0.352
1980 Kadlubar FF. A transversion mutation hypothesis for chemical carcinogenesis by N2-substitution of guanine in DNA Chemico-Biological Interactions. 31: 255-263. PMID 7408034 DOI: 10.1016/0009-2797(80)90014-9  0.361
1979 Ketterer B, Kadlubar F, Flammang T, Carne T, Enderby G. Glutathione adducts of N-methyl-4-aminoazobenzene formed in vivo and by reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with glutathione Chemico-Biological Interactions. 25: 7-21. PMID 111801 DOI: 10.1016/0009-2797(79)90065-6  0.34
1974 Poulsen LL, Kadlubar FF, Ziegler DM. Role of the microsomal mixed-function amine oxidase in the oxidation of N,N-disubstituted hydroxylamines. Archives of Biochemistry and Biophysics. 164: 774-775. PMID 4460890 DOI: 10.1016/0003-9861(74)90094-0  0.303
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