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Yann Gambin - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sunde M, Pham CL, Shanmugam N, Baker MO, Steain M, O'Carroll A, Brown JW, Sierecki E, Gambin Y. Competing Interactions between Viral RHIM Amyloid-forming Proteins and Host Functional Amyloid Structures Modulate the Cellular Response to Infection Biophysical Journal. 118: 180a-181a. DOI: 10.1016/J.Bpj.2019.11.1103  0.318
2019 Brown JWP, Bauer A, Polinkovsky ME, Bhumkar A, Hunter DJB, Gaus K, Sierecki E, Gambin Y. Single-molecule detection on a portable 3D-printed microscope. Nature Communications. 10: 5662. PMID 31827096 DOI: 10.1038/S41467-019-13617-0  0.397
2019 O'Carroll A, Coyle J, Gambin Y. Prions and Prion-like assemblies in neurodegeneration and immunity: The emergence of universal mechanisms across health and disease. Seminars in Cell & Developmental Biology. PMID 31818518 DOI: 10.1016/J.Semcdb.2019.11.012  0.365
2019 Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, et al. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nature Communications. 10: 4288. PMID 31537793 DOI: 10.1038/S41467-019-12279-2  0.315
2019 McMahon KA, Wu Y, Gambin Y, Sierecki E, Tillu VA, Hall T, Martel N, Okano S, Moradi SV, Ruelcke JE, Ferguson C, Yap AS, Alexandrov K, Hill MM, Parton RG. Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications. 10: 3279. PMID 31332168 DOI: 10.1038/S41467-019-11111-1  0.402
2018 O'Carroll A, Chauvin B, Brown JWP, Meagher A, Coyle J, Schill J, Bhumkhar A, Hunter DJB, Ve T, Kobe B, Sierecki E, Gambin Y. Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88. Bmc Biology. 16: 149. PMID 30583727 DOI: 10.1186/S12915-018-0611-7  0.363
2018 Pham CL, Shanmugam N, Strange M, O'Carroll A, Brown JW, Sierecki E, Gambin Y, Steain M, Sunde M. Viral M45 and necroptosis-associated proteins form heteromeric amyloid assemblies. Embo Reports. PMID 30498077 DOI: 10.15252/Embr.201846518  0.332
2018 Moustaqil M, Fontaine F, Overman J, McCann A, Bailey TL, Rudolffi Soto P, Bhumkar A, Giles N, Hunter DJB, Gambin Y, Francois M, Sierecki E. Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor. Nucleic Acids Research. PMID 30335167 DOI: 10.1093/Nar/Gky897  0.323
2018 Steinbeck J, Ross IL, Rothnagel R, Gäbelein P, Schulze S, Giles N, Ali R, Drysdale R, Sierecki E, Gambin Y, Stahlberg H, Takahashi Y, Hippler M, Hankamer B. Structure of a PSI-LHCI-cyt bf supercomplex in promoting cyclic electron flow under anaerobic conditions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254175 DOI: 10.1073/Pnas.1809973115  0.324
2018 Jung W, Sierecki E, Bastiani M, O'Carroll A, Alexandrov K, Rae J, Johnston W, Hunter DJB, Ferguson C, Gambin Y, Ariotti N, Parton RG. Cell-free formation and interactome analysis of caveolae. The Journal of Cell Biology. PMID 29716956 DOI: 10.1083/Jcb.201707004  0.345
2018 Fontaine FR, Goodall S, Prokop JW, Howard CB, Moustaqil M, Kumble S, Rasicci DT, Osborne GW, Gambin Y, Sierecki E, Jones ML, Zuegg J, Mahler S, Francois M. Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. Mabs. 1-11. PMID 29648920 DOI: 10.1080/19420862.2018.1451288  0.352
2018 Ariotti N, Rae J, Giles N, Martel N, Sierecki E, Gambin Y, Hall TE, Parton RG. Ultrastructural localisation of protein interactions using conditionally stable nanobodies. Plos Biology. 16: e2005473. PMID 29621251 DOI: 10.1371/Journal.Pbio.2005473  0.451
2018 Hunter DJB, Bhumkar A, Giles N, Sierecki E, Gambin Y. Unexpected instabilities explain batch-to-batch variability in cell-free protein expression systems. Biotechnology and Bioengineering. PMID 29603735 DOI: 10.1002/Bit.26604  0.381
2018 Leitao A, Bhumkar A, Hunter DJB, Gambin Y, Sierecki E. Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein. International Journal of Molecular Sciences. 19. PMID 29364143 DOI: 10.3390/Ijms19020334  0.389
2018 Healey RD, Wojciechowski J, Monserrat-Martinez A, Tan SL, Marquis CP, Sierecki E, Gambin Y, Finch AM, Thordarson P. Design, synthesis and evaluation of N- and C-terminal protein bioconjugates as GPCR agonists. Bioconjugate Chemistry. PMID 29328675 DOI: 10.1021/Acs.Bioconjchem.7B00716  0.305
2017 Gambin Y, Giles N, O'Carroll A, Polinkovsky M, Hunter D, Sierecki E. Single-molecule fluorescence reveals the oligomerisation and folding steps driving the prion-like behaviour of ASC. Journal of Molecular Biology. PMID 29288634 DOI: 10.1016/J.Jmb.2017.12.013  0.469
2017 Moustaqil M, Bhumkar A, Gonzalez L, Raoul L, Hunter DJB, Carrive P, Sierecki E, Gambin Y. A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein-Protein Interactions. International Journal of Molecular Sciences. 18. PMID 29232933 DOI: 10.3390/Ijms18122681  0.449
2017 Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AA, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, et al. Small-Molecule Inhibitors of the SOX18 Transcription Factor. Cell Chemical Biology. PMID 28163017 DOI: 10.1016/J.Chembiol.2017.01.003  0.375
2017 Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AA, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, ... ... Gambin Y, et al. Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. Elife. 6. PMID 28137359 DOI: 10.7554/Elife.21221  0.358
2016 Sierecki E, Giles N, Bowden Q, Polinkovsky ME, Steinbeck J, Arrioti N, Rahman D, Bhumkar A, Nicovich PR, Ross I, Parton RG, Böcking T, Gambin Y. Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence. Scientific Reports. 6: 37630. PMID 27892477 DOI: 10.1038/Srep37630  0.39
2016 Gambin Y, Polinkovsky M, Francois B, Giles N, Bhumkar A, Sierecki E. Confocal Spectroscopy to Study Dimerization, Oligomerization and Aggregation of Proteins: A Practical Guide. International Journal of Molecular Sciences. 17. PMID 27144560 DOI: 10.3390/Ijms17050655  0.464
2016 Gagoski D, Polinkovsky ME, Mureev S, Kunert A, Johnston W, Gambin Y, Alexandrov K. Performance benchmarking of four cell-free protein expression systems. Biotechnology and Bioengineering. 113: 292-300. PMID 26301602 DOI: 10.1002/Bit.25814  0.403
2014 Polinkovsky ME, Gambin Y, Banerjee PR, Erickstad MJ, Groisman A, Deniz AA. Ultrafast cooling reveals microsecond-scale biomolecular dynamics. Nature Communications. 5: 5737. PMID 25517430 DOI: 10.1038/Ncomms6737  0.598
2014 Sierecki E, Stevers LM, Giles N, Polinkovsky ME, Moustaqil M, Mureev S, Johnston WA, Dahmer-Heath M, Skalamera D, Gonda TJ, Gabrielli B, Collins BM, Alexandrov K, Gambin Y. Rapid mapping of interactions between Human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy. Molecular & Cellular Proteomics : McP. 13: 2233-45. PMID 24866125 DOI: 10.1074/Mcp.M113.037275  0.467
2014 Sierecki E, Giles N, Polinkovsky M, Moustaqil M, Alexandrov K, Gambin Y. A cell-free approach to accelerate the study of protein-protein interactions in vitro. Interface Focus. 3: 20130018. PMID 24511386 DOI: 10.1098/Rsfs.2013.0018  0.433
2014 Gambin Y, Ariotti N, McMahon KA, Bastiani M, Sierecki E, Kovtun O, Polinkovsky ME, Magenau A, Jung W, Okano S, Zhou Y, Leneva N, Mureev S, Johnston W, Gaus K, et al. Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. Elife. 3: e01434. PMID 24473072 DOI: 10.7554/Elife.01434  0.415
2014 Han SP, Gambin Y, Gomez GA, Verma S, Giles N, Michael M, Wu SK, Guo Z, Johnston W, Sierecki E, Parton RG, Alexandrov K, Yap AS. Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. The Journal of Biological Chemistry. 289: 7764-75. PMID 24469447 DOI: 10.1074/Jbc.M113.544478  0.321
2012 Ferreon AC, Moosa MM, Gambin Y, Deniz AA. Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape. Proceedings of the National Academy of Sciences of the United States of America. 109: 17826-31. PMID 22826265 DOI: 10.1073/Pnas.1201802109  0.698
2012 Milles S, Koehler C, Gambin Y, Deniz AA, Lemke EA. Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range. Molecular Biosystems. 8: 2531-4. PMID 22739670 DOI: 10.1039/C2Mb25135C  0.678
2012 Tnimov Z, Guo Z, Gambin Y, Nguyen UT, Wu YW, Abankwa D, Stigter A, Collins BM, Waldmann H, Goody RS, Alexandrov K. Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI. The Journal of Biological Chemistry. 287: 26549-62. PMID 22628549 DOI: 10.1074/Jbc.M112.371294  0.331
2012 Polinkovsky ME, Gambin Y, Erickstad M, Deniz A, Groisman A. Inverse Temperature Jump System to Study Fast Protein Folding Kinetics Biophysical Journal. 102: 448a-449a. DOI: 10.1016/J.Bpj.2011.11.2460  0.67
2011 Gambin Y, VanDelinder V, Ferreon AC, Lemke EA, Groisman A, Deniz AA. Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing. Nature Methods. 8: 239-41. PMID 21297620 DOI: 10.1038/Nmeth.1568  0.696
2010 Gambin Y, Deniz AA. Multicolor single-molecule FRET to explore protein folding and binding. Molecular Biosystems. 6: 1540-7. PMID 20601974 DOI: 10.1039/C003024D  0.696
2010 Ferreon AC, Moran CR, Gambin Y, Deniz AA. Single-molecule fluorescence studies of intrinsically disordered proteins. Methods in Enzymology. 472: 179-204. PMID 20580965 DOI: 10.1016/S0076-6879(10)72010-3  0.705
2010 Gambin Y, Simonnet C, VanDelinder V, Deniz A, Groisman A. Ultrafast microfluidic mixer with three-dimensional flow focusing for studies of biochemical kinetics. Lab On a Chip. 10: 598-609. PMID 20162235 DOI: 10.1039/B914174J  0.609
2010 Gambin Y, Lemke EA, Vandelinder V, Groisman A, Deniz AA. High-Resolution smFRET in a Microfluidic Gas Exchange Platform Biophysical Journal. 98: 622a-623a. DOI: 10.1016/J.Bpj.2009.12.3407  0.646
2010 Moran CR, Ferreon ACM, Gambin Y, Deniz AA. Single-Molecule FRET Reveals Altered Binding-Induced Folding Landscape of PD-Related Mutant Protein Alpha-Synuclein Biophysical Journal. 98: 258a. DOI: 10.1016/J.Bpj.2009.12.1402  0.677
2009 Lemke EA, Gambin Y, Vandelinder V, Brustad EM, Liu HW, Schultz PG, Groisman A, Deniz AA. Microfluidic device for single-molecule experiments with enhanced photostability. Journal of the American Chemical Society. 131: 13610-2. PMID 19772358 DOI: 10.1021/Ja9027023  0.624
2009 Vandelinder V, Ferreon AC, Gambin Y, Deniz AA, Groisman A. High-resolution temperature-concentration diagram of alpha-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device. Analytical Chemistry. 81: 6929-35. PMID 19555081 DOI: 10.1021/Ac901008C  0.663
2009 Gambin Y, Schug A, Lemke EA, Lavinder JJ, Ferreon AC, Magliery TJ, Onuchic JN, Deniz AA. Direct single-molecule observation of a protein living in two opposed native structures. Proceedings of the National Academy of Sciences of the United States of America. 106: 10153-8. PMID 19506258 DOI: 10.1073/Pnas.0904461106  0.694
2009 Reffay M, Gambin Y, Benabdelhak H, Phan G, Taulier N, Ducruix A, Hodges RS, Urbach W. Tracking membrane protein association in model membranes. Plos One. 4: e5035. PMID 19337368 DOI: 10.1371/Journal.Pone.0005035  0.366
2009 Ferreon AC, Gambin Y, Lemke EA, Deniz AA. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 5645-50. PMID 19293380 DOI: 10.1073/Pnas.0809232106  0.658
2009 Schug A, Gambin Y, Deniz A, Onuchic J. The Rop-Dimer: A Folded Protein Living Between Two Alternate Structures Biophysical Journal. 96: 568a. DOI: 10.1016/J.Bpj.2008.12.3722  0.656
2006 Gambin Y, Lopez-Esparza R, Reffay M, Sierecki E, Gov NS, Genest M, Hodges RS, Urbach W. Lateral mobility of proteins in liquid membranes revisited. Proceedings of the National Academy of Sciences of the United States of America. 103: 2098-102. PMID 16461891 DOI: 10.1073/Pnas.0511026103  0.392
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