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Paul A. Clarke, Ph.D - Publications

Affiliations: 
1996-1999 Chemistry Florida State University, Tallahassee, FL, United States 
 1999-1999 Chemistry University of Exeter, Exeter, England, United Kingdom 
 1999-2006 Chemistry University of Nottingham, Nottingham, England, United Kingdom 
 2006- Chemistry University of York, York, England, United Kingdom 
Area:
Natural product synthesis
Website:
http://www.york.ac.uk/chemistry/staff/academic/a-c/pclarke/
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Maddocks CJ, Ermanis K, Clarke PA. Asymmetric "Clip-Cycle" Synthesis of Pyrrolidines and Spiropyrrolidines. Organic Letters. PMID 32991808 DOI: 10.1021/acs.orglett.0c03090  0.332
2020 Hawkins K, Patterson A, Clarke PA, Smith DK. Catalytic Gels for a Prebiotically-Relevant Asymmetric Aldol Reaction in Water: From Organocatalyst Design to Hydrogel Discovery and Back Again. Journal of the American Chemical Society. PMID 32023044 DOI: 10.1021/Jacs.9B13156  0.354
2019 Vagkidis N, Brown AJ, Clarke PA. Evaluation of Amino Nitriles and an Amino Imidate as Organo­catalysts in Aldol Reactions Synthesis. 51: 4106-4112. DOI: 10.1055/S-0039-1690150  0.306
2018 Griggs SD, Thompson N, Tape DT, Fabre M, Clarke PA. Correction: Synthesis of highly substituted 2-spiropiperidines. Organic & Biomolecular Chemistry. PMID 30095852 DOI: 10.1039/C8Ob90117A  0.318
2018 Griggs SD, Thompson N, Tape DT, Fabre M, Clarke PA. Synthesis of highly substituted 2-spiropiperidines. Organic & Biomolecular Chemistry. PMID 30067258 DOI: 10.1039/C8Ob01272E  0.431
2018 Griggs SD, Tape DT, Clarke PA. Strategies for the synthesis of spiropiperidines - a review of the last 10 years. Organic & Biomolecular Chemistry. PMID 29993083 DOI: 10.1039/C8Ob01271G  0.36
2017 Steer AM, Bia N, Smith DK, Clarke PA. Prebiotic synthesis of 2-deoxy-d-ribose from interstellar building blocks promoted by amino esters or amino nitriles. Chemical Communications (Cambridge, England). PMID 28884758 DOI: 10.1039/C7Cc06083A  0.338
2017 Griggs SD, Thompson N, Tape DT, Fabre M, Clarke PA. A Two-Step Synthesis of 2-Spiropiperidines. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28561323 DOI: 10.1002/Chem.201702467  0.345
2017 Ermanis K, Hsiao YT, Kaya U, Jeuken A, Clarke PA. The stereodivergent formation of 2,6-cis and 2,6-trans-tetrahydropyrans: experimental and computational investigation of the mechanism of a thioester oxy-Michael cyclization. Chemical Science. 8: 482-490. PMID 28451195 DOI: 10.1039/C6Sc03478K  0.354
2016 Clarke PA, Nasir NM, Sellars PB, Peter AM, Lawson CA, Burroughs JL. Synthesis of 2,6-trans- and 3,3,6-trisubstituted tetrahydropyran-4-ones from Maitland-Japp derived 2H-dihydropyran-4-ones: a total synthesis of diospongin B. Organic & Biomolecular Chemistry. PMID 27340028 DOI: 10.1039/C6Ob01182A  0.415
2015 Rayner PJ, Smith JC, Denneval C, O'Brien P, Clarke PA, Horan RA. Mechanistic interrogation of the asymmetric lithiation-trapping of N-thiopivaloyl azetidine and pyrrolidine. Chemical Communications (Cambridge, England). PMID 26620913 DOI: 10.1039/C5Cc08690F  0.308
2015 Clarke PA, Sellars PB, Nasir NM. A Maitland-Japp inspired synthesis of dihydropyran-4-ones and their stereoselective conversion to functionalised tetrahydropyran-4-ones. Organic & Biomolecular Chemistry. 13: 4743-50. PMID 25804802 DOI: 10.1039/C5Ob00292C  0.406
2014 Nasir NM, Ermanis K, Clarke PA. Strategies for the construction of tetrahydropyran rings in the synthesis of natural products. Organic & Biomolecular Chemistry. 12: 3323-35. PMID 24744139 DOI: 10.1039/C4Ob00423J  0.397
2012 Clarke PA, Ermanis K. Synthesis of the C20-C32 tetrahydropyran core of the phorboxazoles and the C22 epimer via a stereodivergent Michael reaction. Organic Letters. 14: 5550-3. PMID 23088315 DOI: 10.1021/Ol3026523  0.346
2012 Clarke PA, Mistry N, Thomas GH. Synthesis of the complete series of mono acetates of N-acetyl-D-neuraminic acid. Organic & Biomolecular Chemistry. 10: 529-35. PMID 22095310 DOI: 10.1039/C1Ob06348K  0.333
2011 Iqbal M, Black RJ, Winn J, Reeder AT, Blake AJ, Clarke PA. Studies on transannulation reactions across a nine-membered ring: the synthesis of natural product-like structures. Organic & Biomolecular Chemistry. 9: 5062-78. PMID 21597625 DOI: 10.1039/C1Ob05448A  0.405
2011 Clarke PA, Santos S, Mistry N, Burroughs L, Humphries AC. The asymmetric Maitland-Japp reaction and its application to the construction of the C1-C19 bis-pyran unit of phorboxazole B. Organic Letters. 13: 624-7. PMID 21247215 DOI: 10.1021/Ol102860R  0.363
2011 Clarke PA, Sellars PB, Mistry N. Diastereoselective synthesis of functionalized 2-methyltetrahydropyran-4- ones Tetrahedron Letters. 52: 3654-3656. DOI: 10.1016/J.Tetlet.2011.05.022  0.399
2011 Clarke PA, Winn J. Synthesis of an austrodorane sesquiterpenoid core via a transannular Prins cyclization Tetrahedron Letters. 52: 1469-1472. DOI: 10.1016/J.Tetlet.2011.01.093  0.382
2011 Clarke PA. Strategies for the synthesis of tetrahydropyran-containing natural products Tetrahedron. 67: 4959. DOI: 10.1016/J.Tet.2011.04.069  0.35
2011 Iqbal M, Mistry N, Clarke PA. An asymmetric Maitland-Japp reaction: A highly enantioselective synthesis of tetrahydropyran-4-ones Tetrahedron. 67: 4960-4966. DOI: 10.1016/J.Tet.2011.04.043  0.454
2010 Clarke PA, Black RJG, Iqbal M. Investigation of transannelation reactions across a cyclononene ring Synlett. 543-546. DOI: 10.1055/S-0029-1218390  0.396
2010 Clarke PA, Hargreaves JM, Woollaston DJ, Sarmiento RMR. Synthetic studies on the phorboxazoles: A short synthesis of an epi-C23 tetrahydropyran core Tetrahedron Letters. 51: 4731-4733. DOI: 10.1016/J.Tetlet.2010.07.012  0.46
2009 Clarke PA, Cridland AP, Rolla GA, Iqbal M, Bainbridge NP, Whitwood AC, Wilson C. Studies on the synthesis of the ABC rings of (+/-)-hexacyclinic acid. The Journal of Organic Chemistry. 74: 7812-21. PMID 19813768 DOI: 10.1021/Jo901547K  0.416
2009 Clarke PA, Reeder AT, Winn J. Transannulation reactions in the synthesis of natural products Synthesis. 691-709. DOI: 10.1055/S-0028-1083355  0.327
2008 Clarke PA, Zaytsev AV, Morgan TW, Whitwood AC, Wilson C. One-pot synthesis of functionalized piperid-4-ones: a four-component condensation. Organic Letters. 10: 2877-80. PMID 18533668 DOI: 10.1021/Ol801051G  0.351
2007 Clarke PA, Santos S, Martin WHC. Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones Green Chemistry. 9: 438-440. DOI: 10.1039/B700923B  0.501
2007 Clarke PA, Zaytzev AV, Whitwood AC. Pot, atom and step economic (PASE) synthesis of highly functionalized piperidines: a five-component condensation Tetrahedron Letters. 48: 5209-5212. DOI: 10.1016/J.Tetlet.2007.05.141  0.338
2007 Clarke PA, Rolla GA, Cridland AP, Gill AA. An improved synthesis of (2E,4Z)-6-(benzyloxy)-4-bromohexa-2,4-dien-1-ol Tetrahedron. 63: 9124-9128. DOI: 10.1016/J.Tet.2007.06.071  0.362
2006 Clarke PA, Black RJG, Blake AJ. Enantioselective synthesis of the bicyclo[4.3.0]nonane ring system of the pinguisane-type sesquiterpenoids via a Brønsted acid promoted transannular enol alkylation Tetrahedron Letters. 47: 1453-1455. DOI: 10.1016/J.Tetlet.2005.12.084  0.396
2006 Clarke PA, Santos S. Strategies for the formation of tetrahydropyran rings in the synthesis of natural products European Journal of Organic Chemistry. 2045-2053. DOI: 10.1002/Ejoc.200500964  0.348
2005 Clarke PA, Martin WH, Hargreaves JM, Wilson C, Blake AJ. The one-pot, multi-component construction of highly substituted tetrahydropyran-4-ones using the Maitland-Japp reaction. Organic & Biomolecular Chemistry. 3: 3551-63. PMID 16172694 DOI: 10.1039/B508252H  0.544
2005 Clarke PA, Cridland AP. A racemic synthesis of an AB-ring system of hexacyclinic acid. Organic Letters. 7: 4221-4. PMID 16146392 DOI: 10.1021/Ol051633R  0.396
2005 Clarke PA, Martin WH, Hargreaves JM, Wilson C, Blake AJ. Revisiting the Maitland-Japp reaction. Concise construction of highly functionalised tetrahydropyran-4-ones. Chemical Communications (Cambridge, England). 1061-3. PMID 15719116 DOI: 10.1039/B416247A  0.525
2005 Clarke PA, Martin WHC. Exploiting the Maitland-Japp reaction: A synthesis of (±)- centrolobine Tetrahedron. 61: 5433-5438. DOI: 10.1016/J.Tet.2005.04.011  0.497
2005 Clarke PA, Davie RL, Peace S. Synthesis of the B-ring of FR182877. Investigation of the reactions of 6-fumaryl 1,3,8-nonatrienes Tetrahedron. 61: 2335-2351. DOI: 10.1016/J.Tet.2005.01.014  0.452
2005 Clarke PA, Grist M, Ebden M, Wilson C, Blake AJ. Synthetic studies on the DEF-rings of FR182877 and hexacyclinic acid Tetrahedron. 61: 353-363. DOI: 10.1016/J.Tet.2004.10.095  0.444
2005 Clarke PA, Martin WHC. Exploiting the Maitland—Japp Reaction: A Synthesis of (.+-.)-Centrolobine Cheminform. 36. DOI: 10.1002/chin.200541206  0.489
2005 Clarke PA, Martin WHC. An Expedient Synthesis of (.+-.)-Centrolobine. Cheminform. 36. DOI: 10.1002/chin.200513235  0.448
2004 Clarke PA, Cridland AP. Total synthesis highlights Annual Reports On the Progress of Chemistry - Section B. 100: 91-111. DOI: 10.1039/B402095M  0.335
2004 Clarke PA, Martin WHC. An expedient synthesis of (±)-centrolobine Tetrahedron Letters. 45: 9061-9063. DOI: 10.1016/J.Tetlet.2004.10.035  0.529
2004 Clarke PA, Grist M, Ebden M. An iodocyclisation/elimination approach to a DEF-ring core of FR182877 Tetrahedron Letters. 45: 927-929. DOI: 10.1016/J.Tetlet.2003.11.105  0.403
2003 Clarke PA, Grist M, Ebden M, Wilson C. Synthesis of a model DEF-ring core of hexacyclinic acid Chemical Communications. 9: 1560-1561. DOI: 10.1039/B303706A  0.416
2003 Clarke PA, Martin WHC. Synthetic methods: Part (v) protecting groups Annual Reports On the Progress of Chemistry - Section B. 99: 84-103. DOI: 10.1039/B212008A  0.307
2002 Clarke PA, Martin WH. Diastereoselective synthesis of highly substituted tetrahydropyran-4-ones. Organic Letters. 4: 4527-9. PMID 12465929 DOI: 10.1021/Ol027081J  0.548
2002 Clarke PA, Kayaleh NE, Smith MA, Baker JR, Bird SJ, Chan C. A one-step procedure for the monoacylation of symmetrical 1,2-diols. The Journal of Organic Chemistry. 67: 5226-31. PMID 12126410 DOI: 10.1021/Jo0257041  0.356
2002 Clarke PA. Selective mono-acylation of meso- and C2-symmetric 1,3- and 1,4-diols Tetrahedron Letters. 43: 4761-4763. DOI: 10.1016/S0040-4039(02)00935-8  0.336
2002 Clarke PA, Davie RL, Peace S. On the Diels-Alder reactions and the Lewis acid induced rearrangements of 6-fumaryl 1,3,8-nonatrienes Tetrahedron Letters. 43: 2753-2756. DOI: 10.1016/S0040-4039(02)00377-5  0.397
2000 Buck RT, Clarke PA, Coe DM, Drysdale MJ, Ferris L, Haigh D, Moody CJ, Pearson ND, Swann E. The carbenoid approach to peptide synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2160-7. PMID 10926221 DOI: 10.1002/1521-3765(20000616)6:12<2160::Aid-Chem2160>3.0.Co;2-Y  0.377
2000 Clarke PA, Holton RA, Kayaleh NE. Direct one step mono-functionalisation of symmetrical 1,2-diols Tetrahedron Letters. 41: 2687-2690. DOI: 10.1016/S0040-4039(00)00224-0  0.398
1996 Armstrong A, Barsanti PA, Clarke PA, Wood A. Ketone-directed peracid epoxidation of cyclic alkenes Journal of the Chemical Society - Perkin Transactions 1. 1373-1380. DOI: 10.1039/P19960001373  0.56
1996 Armstrong A, Clarke PA, Wood A. Evidence that a dioxirane is not responsible for alkene epoxidation in a ketone–Oxone® system Chemical Communications. 849-850. DOI: 10.1039/Cc9960000849  0.483
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