Year |
Citation |
Score |
2011 |
Fekry MI, Szekely J, Dutta S, Breydo L, Zang H, Gates KS. Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator. Journal of the American Chemical Society. 133: 17641-51. PMID 21954957 DOI: 10.1021/Ja2046149 |
0.792 |
|
2011 |
Fekry MI, Price NE, Zang H, Huang C, Harmata M, Brown P, Daniels JS, Gates KS. Thiol-activated DNA damage by α-bromo-2-cyclopentenone Chemical Research in Toxicology. 24: 217-228. PMID 21250671 DOI: 10.1021/Tx100282B |
0.749 |
|
2006 |
Stover JS, Chowdhury G, Zang H, Guengerich FP, Rizzo CJ. Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases. Chemical Research in Toxicology. 19: 1506-17. PMID 17112239 DOI: 10.1021/Tx0601455 |
0.639 |
|
2006 |
Choi JY, Chowdhury G, Zang H, Angel KC, Vu CC, Peterson LA, Guengerich FP. Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases. The Journal of Biological Chemistry. 281: 38244-56. PMID 17050527 DOI: 10.1074/Jbc.M608369200 |
0.561 |
|
2006 |
Choi JY, Zang H, Angel KC, Kozekov ID, Goodenough AK, Rizzo CJ, Guengerich FP. Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases. Chemical Research in Toxicology. 19: 879-86. PMID 16780368 DOI: 10.1021/Tx060051V |
0.428 |
|
2006 |
Zang H, Chowdhury G, Angel KC, Harris TM, Guengerich FP. Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4. Chemical Research in Toxicology. 19: 859-67. PMID 16780366 DOI: 10.1021/Tx060056S |
0.677 |
|
2006 |
Irimia A, Zang H, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M. Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4. Biochemistry. 45: 5949-56. PMID 16681366 DOI: 10.1021/Bi052511+ |
0.34 |
|
2006 |
Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP. Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. The Journal of Biological Chemistry. 281: 2358-72. PMID 16306039 DOI: 10.1074/Jbc.M510889200 |
0.449 |
|
2005 |
Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ. Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine. Chemical Research in Toxicology. 18: 1701-14. PMID 16300379 DOI: 10.1021/Tx050141K |
0.485 |
|
2005 |
Zang H, Fang Q, Pegg AE, Guengerich FP. Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase. The Journal of Biological Chemistry. 280: 30873-81. PMID 16000301 DOI: 10.1074/Jbc.M505283200 |
0.436 |
|
2005 |
Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP. DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. The Journal of Biological Chemistry. 280: 29750-64. PMID 15965231 DOI: 10.1074/Jbc.M504756200 |
0.435 |
|
2005 |
Zang H, Harris TM, Guengerich FP. Kinetics of nucleotide incorporation opposite polycyclic aromatic hydrocarbon-DNA adducts by processive bacteriophage T7 DNA polymerase. Chemical Research in Toxicology. 18: 389-400. PMID 15720147 DOI: 10.1021/Tx049683C |
0.536 |
|
2005 |
Zang H, Harris TM, Guengerich FP. Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 280: 1165-78. PMID 15533946 DOI: 10.1074/Jbc.M405996200 |
0.56 |
|
2004 |
Breydo L, Zang H, Gates KS. Synthesis and noncovalent DNA-binding properties of thiazole derivatives related to leinamycin Tetrahedron Letters. 45: 5711-5716. DOI: 10.1016/J.Tetlet.2004.05.093 |
0.764 |
|
2003 |
Zang H, Gates KS. Sequence specificity of DNA alkylation by the antitumor natural product leinamycin. Chemical Research in Toxicology. 16: 1539-46. PMID 14680367 DOI: 10.1021/Tx0341658 |
0.779 |
|
2001 |
Breydo L, Zang H, Mitra K, Gates KS. Thiol-independent DNA alkylation by leinamycin. Journal of the American Chemical Society. 123: 2060-1. PMID 11456831 DOI: 10.1021/Ja003309R |
0.735 |
|
2001 |
Zang H, Breydo L, Mitra K, Dannaldson J, Gates KS. DNA alkylation by leinamycin can be triggered by cyanide and phosphines. Bioorganic & Medicinal Chemistry Letters. 11: 1511-5. PMID 11412971 DOI: 10.1016/S0960-894X(01)00196-2 |
0.73 |
|
2000 |
Zang H, Gates KS. DNA binding and alkylation by the "left half" of azinomycin B. Biochemistry. 39: 14968-75. PMID 11101313 DOI: 10.1021/Bi001998D |
0.777 |
|
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