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Dirk Grimm - Publications

Affiliations: 
Heidelberg University Hospital 
Area:
RNAi, gene therapy, AAV, iPS cells, genome engineering
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Year Citation  Score
2023 Theuerkauf SA, Herrera-Carrillo E, John F, Zinser LJ, Molina MA, Riechert V, Thalheimer FB, Börner K, Grimm D, Chlanda P, Berkhout B, Buchholz CJ. AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery. Biomaterials. 303: 122399. PMID 37992599 DOI: 10.1016/j.biomaterials.2023.122399  0.334
2023 Liu J, Koay TW, Maiakovska O, Zayas M, Grimm D. Progress in Bioengineering of Myotropic Adeno-Associated Viral Gene Therapy Vectors. Human Gene Therapy. 34: 350-364. PMID 37082964 DOI: 10.1089/hum.2023.057  0.363
2022 Rapti K, Maiakovska O, Becker J, Szumska J, Zayas M, Bubeck F, Liu J, Gerstmann E, Krämer C, Wiedtke E, Grimm D. Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus (AAV) Capsid Variants. Journal of Visualized Experiments : Jove. PMID 36342179 DOI: 10.3791/64389  0.383
2022 Szumska J, Grimm D. Boosters for adeno-associated virus vector (AAV) (r)evolution. Cytotherapy. PMID 35999132 DOI: 10.1016/j.jcyt.2022.07.005  0.382
2022 Becker J, Fakhiri J, Grimm D. Fantastic AAV Gene Therapy Vectors and How to Find Them-Random Diversification, Rational Design and Machine Learning. Pathogens (Basel, Switzerland). 11. PMID 35890005 DOI: 10.3390/pathogens11070756  0.409
2022 Mann AM, Schäfer W, Adriouch S, Börner K, Grimm D, Braren I, Koch-Nolte F. Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors. Methods in Molecular Biology (Clifton, N.J.). 2510: 129-144. PMID 35776323 DOI: 10.1007/978-1-0716-2384-8_7  0.331
2022 Gadenstaetter AJ, Schmutzler L, Grimm D, Landegger LD. Intranasal application of adeno-associated viruses: a systematic review. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 35597541 DOI: 10.1016/j.trsl.2022.05.002  0.312
2022 Becker J, Stanifer ML, Leist SR, Stolp B, Maiakovska O, West A, Wiedtke E, Börner K, Ghanem A, Ambiel I, Tse LV, Fackler OT, Baric RS, Boulant S, Grimm D. Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV-RNAi expression vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35038579 DOI: 10.1016/j.ymthe.2022.01.024  0.407
2021 Michels A, Frank AM, Günther DM, Mataei M, Börner K, Grimm D, Hartmann J, Buchholz CJ. Lentiviral and adeno-associated vectors efficiently transduce mouse T lymphocytes when targeted to murine CD8. Molecular Therapy. Methods & Clinical Development. 23: 334-347. PMID 34729380 DOI: 10.1016/j.omtm.2021.09.014  0.301
2021 Zhang C, Freistaedter A, Schmelas C, Gunkel M, Dao Thi VL, Grimm D. An RNA Interference/Adeno-Associated Virus Vector-Based Combinatorial Gene Therapy Approach Against Hepatitis E Virus. Hepatology Communications. PMID 34719133 DOI: 10.1002/hep4.1842  0.443
2021 Kremer LPM, Cerrizuela S, Dehler S, Stiehl T, Weinmann J, Abendroth H, Kleber S, Laure A, El Andari J, Anders S, Marciniak-Czochra A, Grimm D, Martin-Villalba A. High throughput screening of novel AAV capsids identifies variants for transduction of adult NSCs within the subventricular zone. Molecular Therapy. Methods & Clinical Development. 23: 33-50. PMID 34553001 DOI: 10.1016/j.omtm.2021.07.001  0.301
2021 Fakhiri J, Grimm D. Best of most possible worlds: Hybrid gene therapy vectors based on parvoviruses and heterologous viruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33831556 DOI: 10.1016/j.ymthe.2021.04.005  0.388
2021 Medert R, Jungmann A, Hildebrand S, Busch M, Grimm D, Flockerzi V, Müller OJ, Most P, Schumacher D, Freichel M. Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart. Pflugers Archiv : European Journal of Physiology. PMID 33580817 DOI: 10.1007/s00424-021-02521-6  0.312
2020 Fakhiri J, Landegger LD, Grimm D. Breaking the sound barrier: Towards next-generation AAV vectors for gene therapy of hearing disorders. Hearing Research. 108092. PMID 33268240 DOI: 10.1016/j.heares.2020.108092  0.333
2020 Weinmann J, Weis S, Sippel J, Tulalamba W, Remes A, El Andari J, Herrmann AK, Pham QH, Borowski C, Hille S, Schönberger T, Frey N, Lenter M, VandenDriessche T, Müller OJ, ... ... Grimm D, et al. Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants. Nature Communications. 11: 5432. PMID 33116134 DOI: 10.1038/s41467-020-19230-w  0.386
2020 El Andari J, Grimm D. Production, Processing, and Characterization of synthetic AAV Gene Therapy Vectors. Biotechnology Journal. e2000025. PMID 32975881 DOI: 10.1002/biot.202000025  0.355
2020 Klein S, Müller TG, Khalid D, Sonntag-Buck V, Heuser AM, Glass B, Meurer M, Morales I, Schillak A, Freistaedter A, Ambiel I, Winter SL, Zimmermann L, Naumoska T, Bubeck F, ... ... Grimm D, et al. SARS-CoV-2 RNA Extraction Using Magnetic Beads for Rapid Large-Scale Testing by RT-qPCR and RT-LAMP. Viruses. 12. PMID 32784757 DOI: 10.3390/V12080863  0.355
2020 Haar J, Krämer C, Grimm D. Lab-Scale Production of Recombinant Adeno-Associated Viruses (AAV) for Expression of Optogenetic Elements. Methods in Molecular Biology (Clifton, N.J.). 2173: 83-100. PMID 32651911 DOI: 10.1007/978-1-0716-0755-8_5  0.481
2020 Mathony J, Harteveld Z, Schmelas C, Upmeier Zu Belzen J, Aschenbrenner S, Sun W, Hoffmann MD, Stengl C, Scheck A, Georgeon S, Rosset S, Wang Y, Grimm D, Eils R, Correia BE, et al. Computational design of anti-CRISPR proteins with improved inhibition potency. Nature Chemical Biology. PMID 32284602 DOI: 10.1038/S41589-020-0518-9  0.322
2020 Fakhiri J, Linse KP, Mietzsch M, Xu M, Schneider MA, Meister M, Schildgen O, Schnitzler P, Soderlund-Venermo M, Agbandje-McKenna M, Grimm D. Impact of natural or synthetic singletons in the capsid of human bocavirus 1 on particle infectivity and immunoreactivity. Journal of Virology. PMID 32213611 DOI: 10.1128/Jvi.00170-20  0.44
2020 Börner K, Kienle E, Huang LY, Weinmann J, Sacher A, Bayer P, Stüllein C, Fakhiri J, Zimmermann L, Westhaus A, Beneke J, Beil N, Wiedtke E, Schmelas C, Miltner D, ... ... Grimm D, et al. Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32105604 DOI: 10.1016/J.Ymthe.2020.02.009  0.364
2020 Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, et al. Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-titer HBV Carrier Mice. Gastroenterology. PMID 32001321 DOI: 10.1053/J.Gastro.2020.01.032  0.381
2019 Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, et al. Ex Vivo/In vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template. Iscience. 23: 100764. PMID 31887661 DOI: 10.1016/J.Isci.2019.100764  0.516
2019 Eichhoff AM, Börner K, Albrecht B, Schäfer W, Baum N, Haag F, Körbelin J, Trepel M, Braren I, Grimm D, Adriouch S, Koch-Nolte F. Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors. Molecular Therapy. Methods & Clinical Development. 15: 211-220. PMID 31687421 DOI: 10.1016/J.Omtm.2019.09.003  0.433
2019 Hentzschel F, Mitesser V, Fraschka SA, Krzikalla D, Carrillo EH, Berkhout B, Bártfai R, Mueller AK, Grimm D. Gene knockdown in malaria parasites via non-canonical RNAi. Nucleic Acids Research. PMID 31680162 DOI: 10.1093/Nar/Gkz927  0.42
2019 Tulalamba W, Weinmann J, Pham QH, El Andari J, VandenDriessche T, Chuah MK, Grimm D. Distinct transduction of muscle tissue in mice after systemic delivery of AAVpo1 vectors. Gene Therapy. PMID 31624368 DOI: 10.1038/S41434-019-0106-3  0.36
2019 Domenger C, Grimm D. Next-generation AAV vectors - don't judge a virus (only) by its cover. Human Molecular Genetics. PMID 31261383 DOI: 10.1093/Hmg/Ddz148  0.525
2019 Hoffmann MD, Aschenbrenner S, Grosse S, Rapti K, Domenger C, Fakhiri J, Mastel M, Börner K, Eils R, Grimm D, Niopek D. Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins. Nucleic Acids Research. PMID 30982889 DOI: 10.1093/Nar/Gkz271  0.343
2019 Fakhiri J, Nickl M, Grimm D. Rapid and Simple Screening of CRISPR Guide RNAs (gRNAs) in Cultured Cells Using Adeno-Associated Viral (AAV) Vectors. Methods in Molecular Biology (Clifton, N.J.). 1961: 111-126. PMID 30912043 DOI: 10.1007/978-1-4939-9170-9_8  0.493
2019 Fakhiri J, Schneider MA, Puschhof J, Stanifer M, Schildgen V, Holderbach S, Voss Y, El Andari J, Schildgen O, Boulant S, Meister M, Clevers H, Yan Z, Qiu J, Grimm D. Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses. Molecular Therapy. Methods & Clinical Development. 12: 202-222. PMID 30766894 DOI: 10.1016/J.Omtm.2019.01.003  0.493
2019 Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM. Publisher Correction: Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments. Nature Genetics. PMID 30647470 DOI: 10.1038/S41588-018-0341-3  0.308
2018 Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM. Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments. Nature Genetics. PMID 30531872 DOI: 10.1038/S41588-018-0298-2  0.346
2018 Herrmann AK, Bender C, Kienle E, Grosse S, El Andari J, Botta J, Schürmann N, Wiedtke E, Niopek D, Grimm D. A robust and all-inclusive pipeline for shuffling of Adeno-associated viruses (AAV). Acs Synthetic Biology. PMID 30513195 DOI: 10.1021/Acssynbio.8B00373  0.436
2018 Bubeck F, Hoffmann MD, Harteveld Z, Aschenbrenner S, Bietz A, Waldhauer MC, Börner K, Fakhiri J, Schmelas C, Dietz L, Grimm D, Correia BE, Eils R, Niopek D. Engineered anti-CRISPR proteins for optogenetic control of CRISPR-Cas9. Nature Methods. 15: 924-927. PMID 30377362 DOI: 10.1038/S41592-018-0178-9  0.319
2018 Senís E, Mosteiro L, Wilkening S, Wiedtke E, Nowrouzi A, Afzal S, Fronza R, Landerer H, Abad M, Niopek D, Schmidt M, Serrano M, Grimm D. AAVvector-mediated in vivo reprogramming into pluripotency. Nature Communications. 9: 2651. PMID 29985406 DOI: 10.1038/S41467-018-05059-X  0.457
2018 Herrmann AK, Grosse S, Börner K, Krämer C, Wiedtke E, Gunkel M, Grimm D. Impact of the assembly-activating protein (AAP) on molecular evolution of synthetic Adeno-associated virus (AAV) capsids. Human Gene Therapy. PMID 29978729 DOI: 10.1089/Hum.2018.085  0.496
2018 Herrmann AK, Grimm D. High-Throughput Dissection of AAV-Host Interactions: The Fast and the Curious. Journal of Molecular Biology. PMID 29782834 DOI: 10.1016/J.Jmb.2018.05.022  0.47
2018 Schmelas C, Grimm D. Split Cas9, not hairs - advancing the therapeutic index of CRISPR technology. Biotechnology Journal. PMID 29316283 DOI: 10.1002/Biot.201700432  0.459
2017 Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN. Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. Science Translational Medicine. 9. PMID 29187645 DOI: 10.1126/Scitranslmed.Aan8081  0.353
2017 Kunze C, Börner K, Kienle E, Orschmann T, Rusha E, Schneider M, Radivojkov-Blagojevic M, Drukker M, Desbordes S, Grimm D, Brack-Werner R. Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes. Glia. PMID 29119608 DOI: 10.1002/Glia.23254  0.313
2017 Grimm D, Büning H. Small but increasingly mighty - Latest advances in AAV vector research, design and evolution. Human Gene Therapy. PMID 28835125 DOI: 10.1089/hum.2017.172  0.371
2017 Große S, Penaud-Budloo M, Herrmann AK, Börner K, Fakhiri J, Laketa V, Krämer C, Wiedtke E, Gunkel M, Ménard L, Ayuso E, Grimm D. Relevance of assembly-activating protein for Adeno-associated virus vector production and capsid protein stability in mammalian and insect cells. Journal of Virology. PMID 28768875 DOI: 10.1128/Jvi.01198-17  0.432
2017 Weinmann J, Grimm D. Next-generation AAV vectors for clinical use: an ever-accelerating race. Virus Genes. PMID 28762205 DOI: 10.1007/S11262-017-1502-7  0.425
2017 Pervolaraki K, Stanifer ML, Münchau S, Renn LA, Albrecht D, Kurzhals S, Senís E, Grimm D, Schröder-Braunstein J, Rabin RL, Boulant S. Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut. Frontiers in Immunology. 8: 459. PMID 28484457 DOI: 10.3389/Fimmu.2017.00459  0.334
2017 Lempp FA, Wiedtke E, Qu B, Roques P, Chemin I, Vondran FW, Le Grand R, Grimm D, Urban S. Sodium taurocholate cotransporting polypeptide is the limiting host factor of Hepatitis B Virus infection in macaque and pig hepatocytes. Hepatology (Baltimore, Md.). PMID 28195359 DOI: 10.1002/Hep.29112  0.402
2017 Sá E Cunha C, Nyboer B, Heiss K, Sanches-Vaz M, Fontinha D, Wiedtke E, Grimm D, Przyborski JM, Mota MM, Prudêncio M, Mueller AK. Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137845 DOI: 10.1073/Pnas.1606419114  0.359
2016 Senís E, Mockenhaupt S, Rupp D, Bauer T, Paramasivam N, Knapp B, Gronych J, Grosse S, Windisch MP, Schmidt F, Theis FJ, Eils R, Lichter P, Schlesner M, Bartenschlager R, ... Grimm D, et al. TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus. Nucleic Acids Research. PMID 27614072 DOI: 10.1093/Nar/Gkw805  0.413
2016 Michler T, Große S, Mockenhaupt S, Röder N, Stückler F, Knapp B, Ko C, Heikenwalder M, Protzer U, Grimm D. Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA. Embo Molecular Medicine. PMID 27473329 DOI: 10.15252/Emmm.201506172  0.526
2016 Ebrahimi-Fakhari D, Wahlster L, Bartz F, Werenbeck-Ueding J, Praggastis M, Zhang J, Joggerst-Thomalla B, Theiss S, Grimm D, Ory DS, Runz H. Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-Pick type C1 disease cells. Human Molecular Genetics. PMID 27378690 DOI: 10.1093/Hmg/Ddw204  0.306
2016 Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA, Kienle E, Bindman JG, Wiedtke E, Hsu BY, Naqvi SJ, Schwabe RF, Corvera CU, Grimm D, Willenbring H. In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis. Cell Stem Cell. 18: 809-816. PMID 27257763 DOI: 10.1016/J.Stem.2016.05.005  0.405
2016 Hentzschel F, Herrmann AK, Mueller AK, Grimm D. Plasmodium meets AAV - the (un)likely marriage of parasitology and virology, and how to make the match. Febs Letters. PMID 27117587 DOI: 10.1002/1873-3468.12187  0.324
2016 Liesche C, Venkatraman L, Aschenbrenner S, Grosse S, Grimm D, Eils R, Beaudouin J. Death receptor-based enrichment of Cas9-expressing cells. Bmc Biotechnology. 16: 17. PMID 26883910 DOI: 10.1186/S12896-016-0250-4  0.394
2016 Wilkening S, Afzal S, Senís E, Fronza R, Kalle Cv, Grimm D, Schmidt M. 470. New Insights into rAAV Integration Mechanisms by Targeted Enrichment Sequencing Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33279-8  0.374
2016 Grosse S, Penaud-Budloo M, Ayuso E, Grimm D. 302. Molecular AAV Capsid Evolution Is Not Primarily Restricted by Inadvertent Shuffling of the Assembly-Activating Protein AAP Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33111-2  0.451
2016 Fakhiri J, Schneider M, Kailasan S, Meister M, McKenna MA, Yan Z, Qiu J, Grimm D. 254. New Chimeric Gene Therapy Vectors Based on Four Different Mammalian Bocaviruses Molecular Therapy. 24: S100. DOI: 10.1016/S1525-0016(16)33063-5  0.534
2016 Michler T, Kosinska A, Jäger C, Röder N, Grimm D, Heikenwälder M, Roggendorf M, Protzer U. RNA Interference Mediated Suppression of HBV Transcripts Restores HBV-Specific Immunity and Enhances the Efficacy of Therapeutic Vaccination Journal of Hepatology. 64: S148-S149. DOI: 10.1016/S0168-8278(16)00039-8  0.358
2015 Grimm D, Zolotukhin S. E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal-Tailored Acceleration of AAV Evolution. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1819-1831. PMID 28142019 DOI: 10.1038/mt.2015.173  0.317
2015 Singer M, Marshall J, Heiss K, Mair GR, Grimm D, Mueller AK, Frischknecht F. Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining. Genome Biology. 16: 249. PMID 26573820 DOI: 10.1186/S13059-015-0811-1  0.324
2015 Grimm D, Zolotukhin S. E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal-Tailored Acceleration of AAV Evolution. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26388463 DOI: 10.1038/Mt.2015.173  0.428
2015 Mockenhaupt S, Grosse S, Rupp D, Bartenschlager R, Grimm D. Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys. Proceedings of the National Academy of Sciences of the United States of America. 112: E4007-16. PMID 26170322 DOI: 10.1073/Pnas.1510476112  0.513
2015 Mueller S, Huard J, Waldow K, Huang X, D'Alessandro LA, Bohl S, Börner K, Grimm D, Klamt S, Klingmüller U, Schilling M. T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes. Molecular Systems Biology. 11: 795. PMID 26148348 DOI: 10.15252/Msb.20156032  0.326
2015 Schmidt F, Grimm D. CRISPR genome engineering and viral gene delivery: a case of mutual attraction. Biotechnology Journal. 10: 258-72. PMID 25663455 DOI: 10.1002/Biot.201400529  0.477
2015 Michler T, Grosse S, Mockenhaupt S, Protzer U, Grimm D. 699. shRNA Sense Strand Neutralization Reduces Off-Targeting, Ameliorates Toxicity and Enhances Efficacy of RNAi-Based HBV Gene Therapy Molecular Therapy. 23: S278. DOI: 10.1016/S1525-0016(16)34308-8  0.526
2015 Lederle M, Tegeler K, Cerny D, Zessin P, Grimm D. 697. New Insights Into the Mechanisms of Argonaute Protein Competition and Implications for RNAi Gene Therapies Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34306-4  0.505
2015 Boerner K, Fischer E, Schnitzler P, Fortes P, Kräusslich H, Grimm D. 648. Non-Coding RNAs as Clinically Relevant Host Factors and Target Molecules in HIV-1 Infection Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34257-5  0.319
2015 Boerner K, Kienle E, Sacher A, Huang L, Bechtle M, Wiedtke E, Bayer P, Kräusslich H, Agbandje-McKenna M, Grimm D. 307. Rational Development of 12 Different AAV Serotypes as Scaffolds for Peptide Display Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33916-8  0.33
2015 Senís E, Mosteiro L, Wilkening S, Schmidt M, Serrano M, Grimm D. 300. AAV Vector-Mediated In Vivo Reprogramming of Various Cell Types in Adult Mice Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33909-0  0.521
2015 Schmidt F, Beaudouin J, Börner K, Grimm D. 117. AAV-TRISPR – A Novel Versatile AAV Vector Kit for Combinatorial CRISPR and RNAi Expression Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33722-4  0.537
2015 Boerner K, Nickl M, Schmidt F, Gnirck A, Bayer P, Kräusslich H, Grimm D. 56. AAV Vector-Mediated CRISPR Attacks on Proviral HIV-1 DNA for Purging of Cellular Reservoirs Molecular Therapy. 23: S25. DOI: 10.1016/S1525-0016(16)33661-9  0.383
2015 Michler T, Grosse S, Mockenhaupt S, Heikenwaelder M, Grimm D, Protzer U. P0563 : RNAi-based gene therapy for chronic hepatitis B: Evaluation in a murine model Journal of Hepatology. 62: S526. DOI: 10.1016/S0168-8278(15)30770-4  0.354
2014 Uhrig-Schmidt S, Geiger M, Luippold G, Birk G, Mennerich D, Neubauer H, Grimm D, Wolfrum C, Kreuz S. Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors. Plos One. 9: e116288. PMID 25551639 DOI: 10.1371/Journal.Pone.0116288  0.441
2014 Carnero E, Barriocanal M, Segura V, Guruceaga E, Prior C, Börner K, Grimm D, Fortes P. Type I Interferon Regulates the Expression of Long Non-Coding RNAs. Frontiers in Immunology. 5: 548. PMID 25414701 DOI: 10.3389/Fimmu.2014.00548  0.416
2014 Hentzschel F, Hammerschmidt-Kamper C, Börner K, Heiss K, Knapp B, Sattler JM, Kaderali L, Castoldi M, Bindman JG, Malato Y, Willenbring H, Mueller AK, Grimm D. AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2130-41. PMID 25189739 DOI: 10.1038/Mt.2014.172  0.368
2014 Senís E, Fatouros C, Große S, Wiedtke E, Niopek D, Mueller AK, Börner K, Grimm D. CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox. Biotechnology Journal. 9: 1402-12. PMID 25186301 DOI: 10.1002/Biot.201400046  0.539
2014 Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W. A chemical switch for controlling viral infectivity. Chemical Communications (Cambridge, England). 50: 10319-22. PMID 25058661 DOI: 10.1039/C4Cc03292F  0.306
2013 Börner K, Niopek D, Cotugno G, Kaldenbach M, Pankert T, Willemsen J, Zhang X, Schürmann N, Mockenhaupt S, Serva A, Hiet MS, Wiedtke E, Castoldi M, Starkuviene V, Erfle H, ... ... Grimm D, et al. Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines. Nucleic Acids Research. 41: e199. PMID 24049077 DOI: 10.1093/Nar/Gkt836  0.495
2013 Schürmann N, Trabuco LG, Bender C, Russell RB, Grimm D. Molecular dissection of human Argonaute proteins by DNA shuffling. Nature Structural & Molecular Biology. 20: 818-26. PMID 23748378 DOI: 10.1038/Nsmb.2607  0.355
2012 Grimm D, Dalmay T, van Rij RP. Everybody wins! Poland hosts thrilling competitions of viruses, RNAi and football teams. Embo Reports. 13: 874-6. PMID 22986551 DOI: 10.1038/Embor.2012.136  0.411
2012 Grimm D. All for one, one for all: new combinatorial RNAi therapies combat hepatitis C virus evolution. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1661-3. PMID 22945230 DOI: 10.1038/Mt.2012.173  0.412
2012 Kienle E, Senís E, Börner K, Niopek D, Wiedtke E, Grosse S, Grimm D. Engineering and evolution of synthetic adeno-associated virus (AAV) gene therapy vectors via DNA family shuffling. Journal of Visualized Experiments : Jove. PMID 22491297 DOI: 10.3791/3819  0.462
2012 Valdmanis PN, Gu S, Schüermann N, Sethupathy P, Grimm D, Kay MA. Expression determinants of mammalian argonaute proteins in mediating gene silencing. Nucleic Acids Research. 40: 3704-13. PMID 22210886 DOI: 10.1093/Nar/Gkr1274  0.498
2011 Malato Y, Naqvi S, Schürmann N, Ng R, Wang B, Zape J, Kay MA, Grimm D, Willenbring H. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. The Journal of Clinical Investigation. 121: 4850-60. PMID 22105172 DOI: 10.1172/Jci59261  0.545
2011 Grimm D. The dose can make the poison: lessons learned from adverse in vivo toxicities caused by RNAi overexpression. Silence. 2: 8. PMID 22029761 DOI: 10.1186/1758-907X-2-8  0.385
2011 Mockenhaupt S, Schürmann N, Grimm D. When cellular networks run out of control: global dysregulation of the RNAi machinery in human pathology and therapy. Progress in Molecular Biology and Translational Science. 102: 165-242. PMID 21846572 DOI: 10.1016/B978-0-12-415795-8.00006-4  0.465
2011 Gu S, Jin L, Zhang F, Huang Y, Grimm D, Rossi JJ, Kay MA. Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes. Proceedings of the National Academy of Sciences of the United States of America. 108: 9208-13. PMID 21576459 DOI: 10.1073/Pnas.1018023108  0.538
2011 Mockenhaupt S, Grimm D. Vectorology: Adeno-associated viruses for efficient gene targeting in human cells | Vektorologie: Adeno-assoziierte viren für effizientes gene targeting in humanen zellen Biospektrum. 17: 533-536. DOI: 10.1007/sl2268-011-0085-4  0.303
2011 Mockenhaupt S, Grimm D. Adeno-assoziierte Viren für effizientes Gene Targeting in humanen Zellen Biospektrum. 17: 533-536. DOI: 10.1007/S12268-011-0085-4  0.395
2010 Grimm D, Wang L, Lee JS, Schürmann N, Gu S, Börner K, Storm TA, Kay MA. Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver. The Journal of Clinical Investigation. 120: 3106-19. PMID 20697157 DOI: 10.1172/Jci43565  0.643
2010 Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, Heissmeyer V, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, dos Santos FB, Jalili R, ... ... Grimm D, et al. Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. Plos Pathogens. 6: e1000764. PMID 20169186 DOI: 10.1371/Journal.Ppat.1000764  0.565
2010 Beer S, Bellovin DI, Lee JS, Komatsubara K, Wang LS, Koh H, Börner K, Storm TA, Davis CR, Kay MA, Felsher DW, Grimm D. Low-level shRNA cytotoxicity can contribute to MYC-induced hepatocellular carcinoma in adult mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 161-70. PMID 19844192 DOI: 10.1038/Mt.2009.222  0.593
2010 Börner K, Grimm D. Use of small RNAs for therapeutic gene silencing: Risk versus benefit Drug Discovery Today: Technologies. 7: e51-e57. DOI: 10.1016/J.Ddtec.2010.07.003  0.434
2009 Grimm D. Small silencing RNAs: state-of-the-art. Advanced Drug Delivery Reviews. 61: 672-703. PMID 19427885 DOI: 10.1016/J.Addr.2009.05.002  0.431
2008 Giering JC, Grimm D, Storm TA, Kay MA. Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1630-6. PMID 18665161 DOI: 10.1038/Mt.2008.144  0.78
2008 Doege H, Grimm D, Falcon A, Tsang B, Storm TA, Xu H, Ortegon AM, Kazantzis M, Kay MA, Stahl A. Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia. The Journal of Biological Chemistry. 283: 22186-92. PMID 18524776 DOI: 10.1074/Jbc.M803510200  0.511
2008 Grimm D, Lee JS, Wang L, Desai T, Akache B, Storm TA, Kay MA. In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses. Journal of Virology. 82: 5887-911. PMID 18400866 DOI: 10.1128/Jvi.00254-08  0.631
2008 Streetz KL, Doyonnas R, Grimm D, Jenkins DD, Fuess S, Perryman S, Lin J, Trautwein C, Shizuru J, Blau H, Sylvester KG, Kay MA. Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells. Hepatology (Baltimore, Md.). 47: 706-18. PMID 18220289 DOI: 10.1002/Hep.22012  0.495
2007 Grimm D, Kay MA. Therapeutic application of RNAi: is mRNA targeting finally ready for prime time? The Journal of Clinical Investigation. 117: 3633-41. PMID 18060021 DOI: 10.1172/Jci34129  0.544
2007 Grimm D, Kay MA. RNAi and gene therapy: a mutual attraction. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 473-81. PMID 18024667 DOI: 10.1182/Asheducation-2007.1.473  0.649
2007 Paskowitz DM, Greenberg KP, Yasumura D, Grimm D, Yang H, Duncan JL, Kay MA, Lavail MM, Flannery JG, Vollrath D. Rapid and stable knockdown of an endogenous gene in retinal pigment epithelium. Human Gene Therapy. 18: 871-80. PMID 17892416 DOI: 10.1089/Hum.2007.065  0.642
2007 Grimm D, Kay MA. Combinatorial RNAi: a winning strategy for the race against evolving targets? Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 878-88. PMID 17311009 DOI: 10.1038/Sj.Mt.6300116  0.64
2007 Akache B, Grimm D, Shen X, Fuess S, Yant SR, Glazer DS, Park J, Kay MA. A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 330-9. PMID 17235311 DOI: 10.1038/Sj.Mt.6300053  0.696
2006 Akache B, Grimm D, Pandey K, Yant SR, Xu H, Kay MA. The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. Journal of Virology. 80: 9831-6. PMID 16973587 DOI: 10.1128/Jvi.00878-06  0.616
2006 Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature. 441: 537-41. PMID 16724069 DOI: 10.1038/Nature04791  0.65
2006 Grimm D, Kay MA. Therapeutic short hairpin RNA expression in the liver: viral targets and vectors. Gene Therapy. 13: 563-75. PMID 16453009 DOI: 10.1038/Sj.Gt.3302727  0.592
2006 Müller OJ, Leuchs B, Pleger ST, Grimm D, Franz WM, Katus HA, Kleinschmidt JA. Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors. Cardiovascular Research. 70: 70-8. PMID 16448634 DOI: 10.1016/J.Cardiores.2005.12.017  0.68
2006 Grimm D, Pandey K, Nakai H, Storm TA, Kay MA. Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype. Journal of Virology. 80: 426-39. PMID 16352567 DOI: 10.1128/Jvi.80.1.426-439.2006  0.637
2006 Giering JC, Grimm D, Storm TA, Xu H, Kay MA. 796. Pol II-Driven shRNA as an Effective Hepatitis B Virus Therapeutic Molecular Therapy. 13: S308-S309. DOI: 10.1016/J.Ymthe.2006.08.885  0.772
2006 Grimm D, Lee JS, Storm TA, Kay MA. 742. Molecular Evolution of Adeno-Associated Viral (AAV) Vectors Via DNA Family Shuffling of Primate and Non-Primate Serotypes Molecular Therapy. 13: S287. DOI: 10.1016/J.Ymthe.2006.08.824  0.643
2006 Hebert ML, Grimm D, Storm TA, Kay MA. 489. Treatment for Hemophilia B Using Self- Complimentary AAV8 Vectors Molecular Therapy. 13: S189-S190. DOI: 10.1016/J.Ymthe.2006.08.559  0.656
2006 Akache B, Fuess S, Grimm D, Kay MA. 103. A Screen for Host Cellular Proteins That Interact with Adeno-Associated Virus Capsid Proteins Reveals Proteins Involved in AAV8 Transduction Molecular Therapy. 13: S42-S43. DOI: 10.1016/J.Ymthe.2006.08.123  0.609
2006 Grimm D, Streetz KL, Storm TA, Jopling CL, Lee JS, Kay MA. 805. Fatality in Mice Due to Oversaturation of Cellular Micro/Short Hairpin RNA Pathways Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1226  0.661
2006 Grimm D, Lee JS, Streetz KL, Storm TA, Kay MA. 1066. A Novel Class of Miniature Stabilized Double-Stranded AAV (msdsAAV) Vectors for the In Vivo Expression of Short Hairpin RNAs Molecular Therapy. 13: S409. DOI: 10.1016/J.Ymthe.2006.08.1164  0.626
2005 Riu E, Grimm D, Huang Z, Kay MA. Increased maintenance and persistence of transgenes by excision of expression cassettes from plasmid sequences in vivo. Human Gene Therapy. 16: 558-70. PMID 15916481 DOI: 10.1089/Hum.2005.16.558  0.611
2005 Grimm D, Pandey K, Kay MA. Adeno-associated virus vectors for short hairpin RNA expression. Methods in Enzymology. 392: 381-405. PMID 15644194 DOI: 10.1016/S0076-6879(04)92023-X  0.669
2005 Grimm D, Pandey K, Streetz KL, Kay MA. 857. A Versatile and Efficient Viral Vector Platform for Stable In Vivo Expression of Short Hairpin RNA Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.400  0.682
2005 Grimm D, Streetz KL, Pandey K, Storm TA, Kay MA. 87. Determinants of Toxicity Induced by In Vivo Expression of Short Hairpin RNA from AAV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.065  0.688
2004 Grimm D, Streetz KL, Storm TA, Nakai H, McCaffrey AP, Huang Z, Salazar FH, Marion PL, Kay MA. 371. Complete Inhibition of Hepatitis B Virus Gene Expression In Vivo with Short Hairpin RNA Expressed from a Novel Double-Stranded, Bi-Cistronic Adeno-Associated Virus Pseudotype 8 Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.918  0.659
2004 Grimm D, Nakai H, Storm TA, Riu EP, Kay MA. 96. Transgene Expression from Recombinant AAV-8 Vectors in the Liver Occurs Independently of the Serotype Origin of the Viral Inverted Terminal Repeats Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.031  0.635
2003 Grimm D, Kay MA. From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Current Gene Therapy. 3: 281-304. PMID 12871018 DOI: 10.2174/1566523034578285  0.643
2003 Grimm D, Zhou S, Nakai H, Thomas CE, Storm TA, Fuess S, Matsushita T, Allen J, Surosky R, Lochrie M, Meuse L, McClelland A, Colosi P, Kay MA. Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy. Blood. 102: 2412-9. PMID 12791653 DOI: 10.1182/Blood-2003-02-0495  0.647
2003 Grimm D, Kay MA, Kleinschmidt JA. Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 839-50. PMID 12788658 DOI: 10.1016/S1525-0016(03)00095-9  0.745
2002 Grimm D. Production methods for gene transfer vectors based on adeno-associated virus serotypes. Methods (San Diego, Calif.). 28: 146-57. PMID 12413413 DOI: 10.1016/S1046-2023(02)00219-0  0.515
2002 Rohr UP, Kronenwett R, Grimm D, Kleinschmidt J, Haas R. Primary human cells differ in their susceptibility to rAAV-2-mediated gene transfer and duration of reporter gene expression. Journal of Virological Methods. 105: 265-75. PMID 12270659 DOI: 10.1016/S0166-0934(02)00117-9  0.629
2001 Jiang S, Altmann A, Grimm D, Kleinschmidt JA, Schilling T, Germann C, Haberkorn U. Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors. Cancer Gene Therapy. 8: 469-72. PMID 11498767 DOI: 10.1038/Sj.Cgt.7700327  0.635
2001 King JA, Dubielzig R, Grimm D, Kleinschmidt JA. DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids. The Embo Journal. 20: 3282-91. PMID 11406604 DOI: 10.1093/Emboj/20.12.3282  0.604
2000 Kunke D, Grimm D, Denger S, Kreuzer J, Delius H, Komitowski D, Kleinschmidt JA. Preclinical study on gene therapy of cervical carcinoma using adeno-associated virus vectors. Cancer Gene Therapy. 7: 766-77. PMID 10830724 DOI: 10.1038/Sj.Cgt.7700178  0.638
1999 Grimm D, Kleinschmidt JA. Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use. Human Gene Therapy. 10: 2445-50. PMID 10543610 DOI: 10.1089/10430349950016799  0.683
1999 Grimm D, Kern A, Pawlita M, Ferrari F, Samulski R, Kleinschmidt J. Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2. Gene Therapy. 6: 1322-30. PMID 10455443 DOI: 10.1038/Sj.Gt.3300946  0.621
1999 Hörster A, Teichmann B, Hormes R, Grimm D, Kleinschmidt J, Sczakiel G. Recombinant AAV-2 harboring gfp-antisense/ribozyme fusion sequences monitor transduction, gene expression, and show anti-HIV-1 efficacy. Gene Therapy. 6: 1231-8. PMID 10455431 DOI: 10.1038/Sj.Gt.3300955  0.664
1999 Hermens WT, ter Brake O, Dijkhuizen PA, Sonnemans MA, Grimm D, Kleinschmidt JA, Verhaagen J. Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system. Human Gene Therapy. 10: 1885-91. PMID 10446928 DOI: 10.1089/10430349950017563  0.673
1998 Grimm D, Kern A, Rittner K, Kleinschmidt JA. Novel tools for production and purification of recombinant adenoassociated virus vectors. Human Gene Therapy. 9: 2745-60. PMID 9874273 DOI: 10.1089/Hum.1998.9.18-2745  0.685
1997 Weger S, Wistuba A, Grimm D, Kleinschmidt JA. Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins. Journal of Virology. 71: 8437-47. PMID 9343200 DOI: 10.1128/Jvi.71.11.8437-8447.1997  0.672
1997 Wistuba A, Kern A, Weger S, Grimm D, Kleinschmidt JA. Subcellular compartmentalization of adeno-associated virus type 2 assembly. Journal of Virology. 71: 1341-52. PMID 8995658 DOI: 10.1128/Jvi.71.2.1341-1352.1997  0.617
Low-probability matches (unlikely to be authored by this person)
2018 Michler T, Kosinska A, Bunse T, Heikenwälder M, Grimm D, Milstein S, Sepp-Lorenzino L, Protzer U. Combinatorial RNAi/vaccination therapy for chronic hepatitis B achieves long-term functional cure in preclinical mouse model Journal of Hepatology. 68: S16. DOI: 10.1016/S0168-8278(18)30250-2  0.299
2021 Cheng M, Dietz L, Gong Y, Eichler F, Nammour J, Ng C, Grimm D, Maguire CA. Neutralizing antibody evasion and transduction with purified extracellular vesicle-enveloped AAV vectors. Human Gene Therapy. PMID 34445894 DOI: 10.1089/hum.2021.122  0.295
2017 Michler T, Kosinska A, Bunse T, Heikenwälder M, Grimm D, Milstein S, Sepp-Lorenzino L, Protzer U. Preclinical study of a combinatorial RNAi/vaccination therapy as a potential cure for chronic hepatitis B Journal of Hepatology. 66: S112. DOI: 10.1016/S0168-8278(17)30483-X  0.291
2017 Lou WP, Mateos A, Koch M, Klussman S, Yang C, Lu N, Kumar S, Limpert S, Göpferich M, Zschaetzsch M, Sliwinski C, Kenzelmann M, Seedorf M, Maillo C, Senis E, ... Grimm D, et al. Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1. Frontiers in Molecular Neuroscience. 10: 445. PMID 29379413 DOI: 10.3389/Fnmol.2017.00445  0.289
2022 Maurer L, El Andari J, Rapti K, Spreyer L, Steinmann E, Grimm D, Dao Thi VL. Induction of Hepatitis E Virus Anti-ORF3 Antibodies from Systemic Administration of a Muscle-Specific Adeno-Associated Virus (AAV) Vector. Viruses. 14. PMID 35215859 DOI: 10.3390/v14020266  0.283
2022 Bauer A, Puglisi M, Nagl D, Schick JA, Werner T, Klingl A, El Andari J, Hornung V, Kessler H, Götz M, Grimm D, Brack-Werner R. Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104979. PMID 35398994 DOI: 10.1002/advs.202104979  0.282
2022 El Andari J, Renaud-Gabardos E, Tulalamba W, Weinmann J, Mangin L, Pham QH, Hille S, Bennett A, Attebi E, Bourges E, Leborgne C, Guerchet N, Fakhiri J, Krämer C, Wiedtke E, ... ... Grimm D, et al. Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders. Science Advances. 8: eabn4704. PMID 36129972 DOI: 10.1126/sciadv.abn4704  0.272
2013 Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, et al. Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation. 128: 1420-32. PMID 23956210 DOI: 10.1161/Circulationaha.112.001357  0.269
2019 Tabatabai J, Fakhiri J, Meyburg J, Linse KP, Xu M, Söderlund-Venermo M, Grimm D, Schnitzler P. Severe Human Bocavirus 1 Respiratory Tract Infection in an Immunodeficient Child With Fatal Outcome. The Pediatric Infectious Disease Journal. PMID 31033910 DOI: 10.1097/Inf.0000000000002354  0.264
2022 Rovai A, Chung B, Hu Q, Hook S, Yuan Q, Kempf T, Schmidt F, Grimm D, Talbot SR, Steinbrück L, Götting J, Bohne J, Krooss SA, Ott M. In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Nature Communications. 13: 5215. PMID 36064805 DOI: 10.1038/s41467-022-32906-9  0.264
2013 Ma X, Wehland M, Schulz H, Saar K, Hübner N, Infanger M, Bauer J, Grimm D. Genomic approach to identify factors that drive the formation of three-dimensional structures by EA.hy926 endothelial cells. Plos One. 8: e64402. PMID 23675535 DOI: 10.1371/journal.pone.0064402  0.26
2014 Michler T, Mockenhaupt S, Grosse S, Grimm D, Protzer U. Enhancing safety and efficacy of RNAi-based gene therapy for the treatment of chronic hepatitis B International Journal of Infectious Diseases. 21: 33. DOI: 10.1016/J.Ijid.2014.03.483  0.259
2001 Smith J, Herrero R, Erles K, Grimm D, Muñoz N, Bosch FX, Tafur L, Shah KV, Schlehofer JR. Adeno-associated virus seropositivity and HPV-induced cervical cancer in Spain and Colombia. International Journal of Cancer. Journal International Du Cancer. 94: 520-6. PMID 11745438 DOI: 10.1002/Ijc.1496  0.259
2013 Grimm D, Heeg M, Thimme R. Hepatitis B virus: from immunobiology to immunotherapy. Clinical Science (London, England : 1979). 124: 77-85. PMID 23013042 DOI: 10.1042/CS20120169  0.253
2016 Pujol FM, Laketa V, Schmidt F, Mukenhirn M, Müller B, Boulant S, Grimm D, Keppler OT, Fackler OT. HIV-1 Vpu Antagonizes CD317/tetherin by Adaptor protein-1-Mediated Exclusion from Virus Assembly Sites. Journal of Virology. PMID 27170757 DOI: 10.1128/Jvi.00504-16  0.251
2021 Marichal-Gallardo P, Börner K, Pieler MM, Sonntag-Buck V, Obr M, Bejarano D, Wolff MW, Kräusslich HG, Reichl U, Grimm D. Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography. Human Gene Therapy. PMID 33554722 DOI: 10.1089/hum.2019.284  0.25
2011 Grimm D, Blum HE, Thimme R. [Genome-wide association studies]. Deutsche Medizinische Wochenschrift (1946). 136: 95-8. PMID 21225557 DOI: 10.1055/s-0030-1269446  0.249
2023 Thürkauf M, Lin S, Oliveri F, Grimm D, Platt RJ, Rüegg MA. Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9. Nature Communications. 14: 6116. PMID 37777530 DOI: 10.1038/s41467-023-41769-7  0.248
2021 Yu JC, Mietzsch M, Singh A, Jimenez Ybargollin A, Kailasan S, Chipman P, Bhattacharya N, Fakhiri J, Grimm D, Kapoor A, Kučinskaitė-Kodzė I, Žvirblienė A, Söderlund-Venermo M, McKenna R, Agbandje-McKenna M. Characterization of the GBoV1 Capsid and Its Antibody Interactions. Viruses. 13. PMID 33672786 DOI: 10.3390/v13020330  0.246
2015 Aleshcheva G, Wehland M, Sahana J, Bauer J, Corydon TJ, Hemmersbach R, Frett T, Egli M, Infanger M, Grosse J, Grimm D. Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2303-14. PMID 25681461 DOI: 10.1096/fj.14-268151  0.245
2018 Cordas Dos Santos DM, Eilers J, Sosa Vizcaino A, Orlova E, Zimmermann M, Stanulla M, Schrappe M, Börner K, Grimm D, Muckenthaler MU, Kulozik AE, Kunz JB. MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB. Bmc Cancer. 18: 663. PMID 29914415 DOI: 10.1186/S12885-018-4525-0  0.243
2011 Grimm D, Thimme R, Blum HE. HBV life cycle and novel drug targets. Hepatology International. 5: 644-53. PMID 21484123 DOI: 10.1007/s12072-011-9261-3  0.242
2022 Flitsch LJ, Börner K, Stüllein C, Ziegler S, Sonntag-Buck V, Wiedtke E, Semkova V, Au Yeung SWC, Schlee J, Hajo M, Mathews M, Ludwig BS, Kossatz S, Kessler H, Grimm D, et al. Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening. Scientific Reports. 12: 8356. PMID 35589936 DOI: 10.1038/s41598-022-12404-0  0.242
2023 Grosch M, Schraft L, Chan A, Küchenhoff L, Rapti K, Ferreira AM, Kornienko J, Li S, Radke MH, Krämer C, Clauder-Münster S, Perlas E, Backs J, Gotthardt M, Dieterich C, ... ... Grimm D, et al. Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Nature Communications. 14: 3714. PMID 37349314 DOI: 10.1038/s41467-023-39352-1  0.241
2021 Senís E, Mosteiro L, Grimm D, Abad M. A Versatile In Vivo System to Study Myc in Cell Reprogramming. Methods in Molecular Biology (Clifton, N.J.). 2318: 267-279. PMID 34019296 DOI: 10.1007/978-1-0716-1476-1_14  0.236
2021 Murenu E, Pavlou M, Richter L, Rapti K, Just S, Cehajic-Kapetanovic J, Tafrishi N, Hayes A, Scholey R, Lucas R, Büning H, Grimm D, Michalakis S. A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting. Molecular Therapy. Methods & Clinical Development. 20: 587-600. PMID 33665228 DOI: 10.1016/j.omtm.2021.01.011  0.235
2015 Kirchgessner TG, Martin R, Sleph P, Grimm D, Liu X, Lupisella J, Smalley J, Narayanan R, Xie Y, Ostrowski J, Cantor GH, Mohan R, Kick E. Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates. The Journal of Pharmacology and Experimental Therapeutics. 352: 305-14. PMID 25467132 DOI: 10.1124/jpet.114.219923  0.234
2021 Hakim CH, Kumar SRP, Pérez-López DO, Wasala NB, Zhang D, Yue Y, Teixeira J, Pan X, Zhang K, Million ED, Nelson CE, Metzger S, Han J, Louderman JA, Schmidt F, ... ... Grimm D, et al. Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models. Nature Communications. 12: 6769. PMID 34819506 DOI: 10.1038/s41467-021-26830-7  0.22
2018 Wolff G, Taranko AE, Meln I, Weinmann J, Sijmonsma T, Lerch S, Heide D, Billeter AT, Tews D, Krunic D, Fischer-Posovszky P, Müller-Stich BP, Herzig S, Grimm D, Heikenwälder M, et al. Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis. Molecular Metabolism. PMID 30409703 DOI: 10.1016/J.Molmet.2018.10.007  0.219
2009 Grimm D. New concepts for siRNA design: The beauty of asymmetry: Asymmetry in siRNA design Gene Therapy. 16: 827-829. PMID 19404320 DOI: 10.1038/Gt.2009.45  0.214
2014 Uhrig-Schmidt S, Geiger M, Luippold G, Birk G, Mennerich D, Neubauer H, Grimm D, Wolfrum C, Kreuz S. Local application of rAAV serotypes 1, 2, 5, 6 and 8 and rAd into visceral fat pads. Plos One. DOI: 10.1371/Journal.Pone.0116288.G001  0.214
2013 Ma X, Wehland M, Aleshcheva G, Hauslage J, Waßer K, Hemmersbach R, Infanger M, Bauer J, Grimm D. Interleukin-6 expression under gravitational stress due to vibration and hypergravity in follicular thyroid cancer cells. Plos One. 8: e68140. PMID 23844163 DOI: 10.1371/journal.pone.0068140  0.206
2021 Luck R, Karakatsani A, Shah B, Schermann G, Adler H, Kupke J, Tisch N, Jeong HW, Back MK, Hetsch F, D'Errico A, De Palma M, Wiedtke E, Grimm D, Acker-Palmer A, et al. The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner. Cell Reports. 36: 109522. PMID 34407407 DOI: 10.1016/j.celrep.2021.109522  0.204
2013 Aleshcheva G, Sahana J, Ma X, Hauslage J, Hemmersbach R, Egli M, Infanger M, Bauer J, Grimm D. Changes in morphology, gene expression and protein content in chondrocytes cultured on a random positioning machine. Plos One. 8: e79057. PMID 24244418 DOI: 10.1371/journal.pone.0079057  0.197
2014 Grimm D. The genes that turned wildcats into kitty cats Science. 346: 799.  0.195
2023 Moreno Velasquez SD, Gerstmann E, Grimm D. Goody two plasmids: An optimized transient transfection system for AAV vector production. Molecular Therapy. Methods & Clinical Development. 30: 191-193. PMID 37519408 DOI: 10.1016/j.omtm.2023.06.010  0.195
2012 Grosse J, Wehland M, Pietsch J, Ma X, Ulbrich C, Schulz H, Saar K, Hübner N, Hauslage J, Hemmersbach R, Braun M, van Loon J, Vagt N, Infanger M, Eilles C, ... ... Grimm D, et al. Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 639-55. PMID 22024737 DOI: 10.1096/fj.11-194886  0.195
2014 Grimm D, Pietsch J, Wehland M, Richter P, Strauch SM, Lebert M, Magnusson NE, Wise P, Bauer J. The impact of microgravity-based proteomics research. Expert Review of Proteomics. 11: 465-76. PMID 24957700 DOI: 10.1586/14789450.2014.926221  0.193
2012 Magnusson NE, Dyrskjøt L, Grimm D, Wehland M, Pietsch J, Rungby J. Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death. Basic & Clinical Pharmacology & Toxicology. 111: 254-61. PMID 22642398 DOI: 10.1111/j.1742-7843.2012.00902.x  0.192
2022 Melendez E, Chondronasiou D, Mosteiro L, de Villarreal JM, Fernández-Alfara M, Lynch C, Grimm D, Real FX, Alcamí J, Climent N, Pietrocola F, Serrano M. Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development (Cambridge, England). PMID 35420133 DOI: 10.1242/dev.200361  0.187
2014 Grimm D. Animal domestication. The genes that turned wildcats into kitty cats. Science (New York, N.Y.). 346: 799. PMID 25395514 DOI: 10.1126/science.346.6211.799  0.182
2020 Hoffmann MD, Mathony J, Upmeier Zu Belzen J, Harteveld Z, Aschenbrenner S, Stengl C, Grimm D, Correia BE, Eils R, Niopek D. Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein. Nucleic Acids Research. PMID 33330940 DOI: 10.1093/nar/gkaa1198  0.181
2014 Ma X, Pietsch J, Wehland M, Schulz H, Saar K, Hübner N, Bauer J, Braun M, Schwarzwälder A, Segerer J, Birlem M, Horn A, Hemmersbach R, Waßer K, Grosse J, ... ... Grimm D, et al. Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 813-35. PMID 24196587 DOI: 10.1096/fj.13-243287  0.18
2014 Wildgruber R, Weber G, Wise P, Grimm D, Bauer J. Free-flow electrophoresis in proteome sample preparation. Proteomics. 14: 629-36. PMID 24123730 DOI: 10.1002/pmic.201300253  0.177
2022 Becker J, Fischer N, Grimm D. Right on target: The next class of efficient, safe, and specific RNAi triggers. Molecular Therapy. Nucleic Acids. 28: 363-365. PMID 35505965 DOI: 10.1016/j.omtn.2022.03.027  0.17
2015 Wang C, Liu C, Roqueiro D, Grimm D, Schwab R, Becker C, Lanz C, Weigel D. Genome-wide analysis of local chromatin packing in Arabidopsis thaliana. Genome Research. 25: 246-56. PMID 25367294 DOI: 10.1101/Gr.170332.113  0.165
2011 Niopek D, Berrens R, Mockenhaupt S, Lewis MD, Mueller AK, Grimm D. To go, or not to go, that is the question - six personal reflections on how geographic mobility may affect your career and life. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 728-31. PMID 21858845 DOI: 10.1002/Bies.201100083  0.164
2024 Muñoz S, Bertolin J, Jimenez V, Jaén ML, Garcia M, Pujol A, Vilà L, Sacristan V, Barbon E, Ronzitti G, El Andari J, Tulalamba W, Pham QH, Ruberte J, VandenDriessche T, ... ... Grimm D, et al. Treatment of Infantile-Onset Pompe Disease in a Rat Model with Muscle-Directed AAV Gene Therapy. Molecular Metabolism. 101899. PMID 38346589 DOI: 10.1016/j.molmet.2024.101899  0.164
2011 Ulbrich C, Pietsch J, Grosse J, Wehland M, Schulz H, Saar K, Hübner N, Hauslage J, Hemmersbach R, Braun M, van Loon J, Vagt N, Egli M, Richter P, Einspanier R, ... ... Grimm D, et al. Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 185-98. PMID 21865726 DOI: 10.1159/000331730  0.16
2011 Pietsch J, Sickmann A, Weber G, Bauer J, Egli M, Wildgruber R, Infanger M, Grimm D. A proteomic approach to analysing spheroid formation of two human thyroid cell lines cultured on a random positioning machine. Proteomics. 11: 2095-104. PMID 21520503 DOI: 10.1002/pmic.201000817  0.159
2016 Liesche C, Venkatraman L, Aschenbrenner S, Grosse S, Grimm D, Eils R, Beaudouin J. Death receptor-based enrichment of Cas9-expressing cells Bmc Biotechnology. 16. DOI: 10.1186/s12896-016-0250-4  0.158
2013 Wehland M, Ma X, Braun M, Hauslage J, Hemmersbach R, Bauer J, Grosse J, Infanger M, Grimm D. The impact of altered gravity and vibration on endothelial cells during a parabolic flight. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 31: 432-51. PMID 23548630 DOI: 10.1159/000343380  0.156
2011 Grimm D, Thimme R. [Cholestatic liver diseases]. Therapeutische Umschau. Revue ThéRapeutique. 68: 195-9. PMID 21452140 DOI: 10.1024/0040-5930/a000150  0.154
2015 Wehland M, Aleshcheva G, Schulz H, Saar K, Hübner N, Hemmersbach R, Braun M, Ma X, Frett T, Warnke E, Riwaldt S, Pietsch J, Corydon TJ, Infanger M, Grimm D. Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers. Cell Communication and Signaling : Ccs. 13: 18. PMID 25889719 DOI: 10.1186/s12964-015-0095-9  0.153
2015 Riwaldt S, Bauer J, Pietsch J, Braun M, Segerer J, Schwarzwälder A, Corydon TJ, Infanger M, Grimm D. The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions. International Journal of Molecular Sciences. 16: 28296-310. PMID 26633361 DOI: 10.3390/ijms161226108  0.147
2013 Pietsch J, Riwaldt S, Bauer J, Sickmann A, Weber G, Grosse J, Infanger M, Eilles C, Grimm D. Interaction of proteins identified in human thyroid cells. International Journal of Molecular Sciences. 14: 1164-78. PMID 23303277 DOI: 10.3390/ijms14011164  0.146
2023 Stajković N, Liu Y, Arsić A, Meng N, Lyu H, Zhang N, Grimm D, Lerche H, Nikić-Spiegel I. Direct fluorescent labeling of NF186 and NaV1.6 in living primary neurons using bioorthogonal click chemistry. Journal of Cell Science. PMID 37288813 DOI: 10.1242/jcs.260600  0.143
2014 Stokich B, Osgood Q, Grimm D, Moorthy S, Chakraborty N, Menze MA. Cryopreservation of hepatocyte (HepG2) cell monolayers: impact of trehalose. Cryobiology. 69: 281-90. PMID 25127872 DOI: 10.1016/J.Cryobiol.2014.08.001  0.143
2015 Riwaldt S, Pietsch J, Sickmann A, Bauer J, Braun M, Segerer J, Schwarzwälder A, Aleshcheva G, Corydon TJ, Infanger M, Grimm D. Identification of proteins involved in inhibition of spheroid formation under microgravity. Proteomics. PMID 25930030 DOI: 10.1002/pmic.201500067  0.143
2012 Grosse J, Meier K, Bauer TJ, Eilles C, Grimm D. Cell separation by countercurrent centrifugal elutriation: recent developments. Preparative Biochemistry & Biotechnology. 42: 217-33. PMID 22509848 DOI: 10.1080/10826068.2011.602799  0.143
2014 Knapstein J, Grimm D, Wörns MA, Galle PR, Lang H, Zimmermann T. Triple antiviral therapy with telaprevir after liver transplantation: A case series Transplant Research and Risk Management. 6: 73-78. DOI: 10.2147/TRRM.S65651  0.142
2015 Bauer J, Wehland M, Pietsch J, Sickmann A, Weber G, Grimm D. Annotated Gene and Proteome Data Support Recognition of Interconnections Between the Results of Different Experiments in Space Research Microgravity Science and Technology. DOI: 10.1007/s12217-015-9451-z  0.14
2021 Rapti K, Grimm D. Adeno-Associated Viruses (AAV) and Host Immunity - A Race Between the Hare and the Hedgehog. Frontiers in Immunology. 12: 753467. PMID 34777364 DOI: 10.3389/fimmu.2021.753467  0.139
2011 Pietsch J, Bauer J, Egli M, Infanger M, Wise P, Ulbrich C, Grimm D. The effects of weightlessness on the human organism and mammalian cells. Current Molecular Medicine. 11: 350-64. PMID 21568935 DOI: 10.2174/156652411795976600  0.138
2014 Ma X, Sickmann A, Pietsch J, Wildgruber R, Weber G, Infanger M, Bauer J, Grimm D. Proteomic differences between microvascular endothelial cells and the EA.hy926 cell line forming three-dimensional structures. Proteomics. 14: 689-98. PMID 24376074 DOI: 10.1002/pmic.201300453  0.138
2012 Grosse J, Wehland M, Pietsch J, Schulz H, Saar K, Hübner N, Eilles C, Bauer J, Abou-El-Ardat K, Baatout S, Ma X, Infanger M, Hemmersbach R, Grimm D. Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 5124-40. PMID 22964303 DOI: 10.1096/fj.12-215749  0.138
2021 Meng N, Grimm D. Membrane-destabilizing ionizable phospholipids: Novel components for organ-selective mRNA delivery and CRISPR-Cas gene editing. Signal Transduction and Targeted Therapy. 6: 206. PMID 34035211 DOI: 10.1038/s41392-021-00642-z  0.137
2011 Grimm D, Bauer J, Pietsch J, Infanger M, Eucker J, Eilles C, Schoenberger J. Diagnostic and therapeutic use of membrane proteins in cancer cells Current Medicinal Chemistry. 18: 176-190. PMID 21110808 DOI: 10.2174/092986711794088344  0.134
2011 Grimm D, Wise P, Lebert M, Richter P, Baatout S. How and why does the proteome respond to microgravity? Expert Review of Proteomics. 8: 13-27. PMID 21329425 DOI: 10.1586/epr.10.105  0.133
2014 Grosse J, Warnke E, Wehland M, Pietsch J, Pohl F, Wise P, Magnusson NE, Eilles C, Grimm D. Mechanisms of apoptosis in irradiated and sunitinib-treated follicular thyroid cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 19: 480-90. PMID 24213562 DOI: 10.1007/s10495-013-0937-0  0.133
2015 Mahner S, Woelber L, Mueller V, Witzel I, Prieske K, Grimm D, Keller-V Amsberg G, Trillsch F. Beyond Bevacizumab: An Outlook to New Anti-Angiogenics for the Treatment of Ovarian Cancer. Frontiers in Oncology. 5: 211. PMID 26500886 DOI: 10.3389/fonc.2015.00211  0.132
2022 Waithaka A, Maiakovska O, Grimm D, do Nascimento LM, Clayton C. Sequences and proteins that influence mRNA processing in Trypanosoma brucei: Evolutionary conservation of SR-domain and PTB protein functions. Plos Neglected Tropical Diseases. 16: e0010876. PMID 36288402 DOI: 10.1371/journal.pntd.0010876  0.131
2014 Grimm D, Wehland M, Pietsch J, Aleshcheva G, Wise P, van Loon J, Ulbrich C, Magnusson NE, Infanger M, Bauer J. Growing tissues in real and simulated microgravity: new methods for tissue engineering. Tissue Engineering. Part B, Reviews. 20: 555-66. PMID 24597549 DOI: 10.1089/ten.TEB.2013.0704  0.126
2013 Pietsch J, Ma X, Wehland M, Aleshcheva G, Schwarzwälder A, Segerer J, Birlem M, Horn A, Bauer J, Infanger M, Grimm D. Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission. Biomaterials. 34: 7694-705. PMID 23866977 DOI: 10.1016/j.biomaterials.2013.06.054  0.124
2014 Darstein F, König C, Hoppe-Lotichius M, Grimm D, Knapstein J, Mittler J, Lang H, Galle PR, Zimmermann T. Impact of pancreatic comorbidities in patients with end-stage liver disease on outcome after liver transplantation. European Journal of Internal Medicine. 25: 281-5. PMID 24468121 DOI: 10.1016/j.ejim.2014.01.005  0.123
2012 Wehland M, Bauer J, Infanger M, Grimm D. Target-based anti-angiogenic therapy in breast cancer. Current Pharmaceutical Design. 18: 4244-57. PMID 22632607 DOI: 10.2174/138161212802430468  0.122
2012 Pietsch J, Sickmann A, Weber G, Bauer J, Egli M, Wildgruber R, Infanger M, Grimm D. Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces. Proteomics. 12: 2539-46. PMID 22707460 DOI: 10.1002/pmic.201200070  0.122
2012 Ma X, Wildgruber R, Bauer J, Weber G, Infanger M, Grosse J, Grimm D. The use of sigmoid pH gradients in free-flow isoelectric focusing of human endothelial cell proteins. Electrophoresis. 33: 1349-55. PMID 22648801 DOI: 10.1002/elps.201100598  0.119
2013 Azencott CA, Grimm D, Sugiyama M, Kawahara Y, Borgwardt KM. Efficient network-guided multi-locus association mapping with graph cuts. Bioinformatics (Oxford, England). 29: i171-9. PMID 23812981 DOI: 10.1093/Bioinformatics/Btt238  0.118
2014 Ulbrich C, Wehland M, Pietsch J, Aleshcheva G, Wise P, van Loon J, Magnusson N, Infanger M, Grosse J, Eilles C, Sundaresan A, Grimm D. The impact of simulated and real microgravity on bone cells and mesenchymal stem cells. Biomed Research International. 2014: 928507. PMID 25110709 DOI: 10.1155/2014/928507  0.117
2014 Kristensen TB, Knutsson ML, Wehland M, Laursen BE, Grimm D, Warnke E, Magnusson NE. Anti-vascular endothelial growth factor therapy in breast cancer. International Journal of Molecular Sciences. 15: 23024-41. PMID 25514409 DOI: 10.3390/ijms151223024  0.113
2015 Grimm DE, Hornung U. Leica ATRplus - Improved Performance for Automated Target Aiming and Locking | Leica ATRplus - Leistungssteigerung der automatischen Messung und Verfolgung von Prismen Avn Allgemeine Vermessungs-Nachrichten. 122: 269-276.  0.111
2023 Kermani F, Mosqueira M, Peters K, Lemma ED, Rapti K, Grimm D, Bastmeyer M, Laugsch M, Hecker M, Ullrich ND. Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Basic Research in Cardiology. 118: 13. PMID 36988697 DOI: 10.1007/s00395-023-00984-5  0.111
2015 Hernandez JB, Chang C, LeBlanc M, Grimm D, Le Lay J, Kaestner KH, Zheng Y, Montminy M. The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nature Communications. 6: 7216. PMID 26031354 DOI: 10.1038/Ncomms8216  0.108
2011 Grimm DK, Chen SK, Litkouhi BB. Intelligent cell phone restriction based on driver identification profiles 18th World Congress On Intelligent Transport Systems and Its America Annual Meeting 2011. 2: 1219-1224.  0.108
2011 Grimm D, Wehland M, Pietsch J, Infanger M, Bauer J. Drugs interfering with apoptosis in breast cancer. Current Pharmaceutical Design. 17: 272-83. PMID 21348828 DOI: 10.2174/138161211795049723  0.106
2011 Wohllebe S, Ulbrich C, Grimm D, Pietsch J, Erzinger G, Richter R, Lebert M, Richter PR, Häder DP. Photodynamic treatment of Chaoborus crystallinus larvae with chlorophyllin induces necrosis and apoptosis. Photochemistry and Photobiology. 87: 1113-22. PMID 21699544 DOI: 10.1111/j.1751-1097.2011.00958.x  0.104
2015 Llinares-López F, Grimm DG, Bodenham DA, Gieraths U, Sugiyama M, Rowan B, Borgwardt K. Genome-wide detection of intervals of genetic heterogeneity associated with complex traits. Bioinformatics (Oxford, England). 31: i240-i249. PMID 26072488 DOI: 10.1093/Bioinformatics/Btv263  0.103
2016 Grimm D, Lieb J, Weyer V, Vollmar J, Darstein F, Lautem A, Hoppe-Lotichius M, Koch S, Schad A, Schattenberg JM, Wörns MA, Weinmann A, Galle PR, Zimmermann T. Organic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatment Bmc Cancer. 16. DOI: 10.1186/s12885-016-2150-3  0.102
2015 Grimm DG, Azencott CA, Aicheler F, Gieraths U, MacArthur DG, Samocha KE, Cooper DN, Stenson PD, Daly MJ, Smoller JW, Duncan LE, Borgwardt KM. The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity. Human Mutation. 36: 513-23. PMID 25684150 DOI: 10.1002/Humu.22768  0.101
2014 Warnke E, Pietsch J, Wehland M, Bauer J, Infanger M, Görög M, Hemmersbach R, Braun M, Ma X, Sahana J, Grimm D. Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1. Cell Communication and Signaling : Ccs. 12: 32. PMID 24885050 DOI: 10.1186/1478-811X-12-32  0.101
2015 Nielsen OH, Grimm D, Wehland M, Bauer J, Magnusson NE. Anti-Angiogenic Drugs in the Treatment of Metastatic Renal Cell Carcinoma: Advances in Clinical Application. Current Vascular Pharmacology. 13: 381-91. PMID 24548189  0.096
2012 Baraban L, Makarov D, Streubel R, Mönch I, Grimm D, Sanchez S, Schmidt OG. Catalytic Janus motors on microfluidic chip: deterministic motion for targeted cargo delivery. Acs Nano. 6: 3383-9. PMID 22424213 DOI: 10.1021/nn300413p  0.093
2015 Gliddon E, Lauder S, Berk L, Cosgrove V, Grimm D, Dodd S, Suppes T, Berk M. Evaluating discussion board engagement in the MoodSwings online self-help program for bipolar disorder: protocol for an observational prospective cohort study. Bmc Psychiatry. 15: 243. PMID 26462799 DOI: 10.1186/S12888-015-0630-7  0.093
2013 Wehland M, Bauer J, Magnusson NE, Infanger M, Grimm D. Biomarkers for anti-angiogenic therapy in cancer. International Journal of Molecular Sciences. 14: 9338-64. PMID 23629668 DOI: 10.3390/ijms14059338  0.091
2015 Mahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, Petersen C, Mueller V, Jaenicke F, Woelber L. Systemic treatment of vulvar cancer. Expert Review of Anticancer Therapy. 15: 629-37. PMID 25997120 DOI: 10.1586/14737140.2015.1037837  0.087
2015 Svejgaard B, Wehland M, Ma X, Kopp S, Sahana J, Warnke E, Aleshcheva G, Hemmersbach R, Hauslage J, Grosse J, Bauer J, Corydon TJ, Islam T, Infanger M, Grimm D. Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat. Plos One. 10: e0135157. PMID 26274317 DOI: 10.1371/journal.pone.0135157  0.087
2015 Kopp S, Warnke E, Wehland M, Aleshcheva G, Magnusson NE, Hemmersbach R, Juhl Corydon T, Bauer J, Infanger M, Grimm D. Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity. Scientific Reports. 5: 16691. PMID 26576504 DOI: 10.1038/srep16691  0.086
2021 Bubeck F, Grimm D. 'Hit and run' therapy averts macular degeneration. Nature Biomedical Engineering. 5: 132-133. PMID 33580229 DOI: 10.1038/s41551-021-00690-4  0.085
2013 Feragen A, Petersen J, Grimm D, Dirksen A, Pedersen JH, Borgwardt K, de Bruijne M. Geometric tree kernels: classification of COPD from airway tree geometry. Information Processing in Medical Imaging : Proceedings of the ... Conference. 23: 171-83. PMID 24683967 DOI: 10.1007/978-3-642-38868-2_15  0.081
2013 Grimm D, Hagmann J, Koenig D, Weigel D, Borgwardt K. Accurate indel prediction using paired-end short reads. Bmc Genomics. 14: 132. PMID 23442375 DOI: 10.1186/1471-2164-14-132  0.081
2023 Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, ... ... Grimm D, et al. Loss of epigenetic information as a cause of mammalian aging. Cell. PMID 36638792 DOI: 10.1016/j.cell.2022.12.027  0.08
2013 Woelber L, Trillsch F, Kock L, Grimm D, Petersen C, Choschzick M, Jaenicke F, Mahner S. Management of patients with vulvar cancer: a perspective review according to tumour stage. Therapeutic Advances in Medical Oncology. 5: 183-92. PMID 23634196 DOI: 10.1177/1758834012471699  0.079
2015 Darstein F, König C, Hoppe-Lotichius M, Grimm D, Knapstein J, Zimmermann A, Mittler J, Schattenberg JM, Sprinzl MF, Wörns MA, Lang H, Galle PR, Zimmermann T. New onset of diabetes after transplantation is associated with improved patient survival after liver transplantation due to confounding factor. European Journal of Internal Medicine. PMID 26058989 DOI: 10.1016/j.ejim.2015.05.018  0.077
2011 Bláha M, Eisenbeiss H, Grimm D, Limpach P. Direct georeferencing of UAVs International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences - Isprs Archives. 38: 131-136.  0.075
2015 Wuest SL, Richard S, Kopp S, Grimm D, Egli M. Simulated microgravity: critical review on the use of random positioning machines for mammalian cell culture. Biomed Research International. 2015: 971474. PMID 25649075 DOI: 10.1155/2015/971474  0.074
2015 Grimm D. ANIMAL WELFARE. New rules may end U.S. chimpanzee research. Science (New York, N.Y.). 349: 777. PMID 26293932 DOI: 10.1126/science.349.6250.777  0.072
2014 Darstein F, König C, Hoppe-Lotichius M, Grimm D, Knapstein J, Mittler J, Zimmermann A, Otto G, Lang H, Galle PR, Zimmermann T. Preoperative left ventricular hypertrophy is associated with reduced patient survival after liver transplantation. Clinical Transplantation. 28: 236-42. PMID 24372847 DOI: 10.1111/ctr.12304  0.071
2011 Pietsch J, Bauer J, Weber G, Nissum M, Westphal K, Egli M, Grosse J, Schönberger J, Eilles C, Infanger M, Grimm D. Proteome analysis of thyroid cancer cells after long-term exposure to a random positioning machine Microgravity Science and Technology. 23: 381-390. DOI: 10.1007/s12217-011-9258-5  0.068
2014 Grimm D. Animal welfare accreditation called into question: PETA study finds violations more often in approved labs Science. 345: 988.  0.068
2015 Nielsen OH, Grimm D, Wehland M, Bauer J, Magnusson NE. Anti-angiogenic drugs in the treatment of metastatic renal cell carcinoma: Advances in clinical application Current Vascular Pharmacology. 13: 381-391.  0.068
2013 Heinzig A, Mikolajick T, Trommer J, Grimm D, Weber WM. Dually active silicon nanowire transistors and circuits with equal electron and hole transport. Nano Letters. 13: 4176-81. PMID 23919720 DOI: 10.1021/nl401826u  0.068
2015 Aleshcheva G, Bauer J, Hemmersbach R, Egli M, Wehland M, Grimm D. Tissue Engineering of Cartilage on Ground-Based Facilities Microgravity Science and Technology. 1-9. DOI: 10.1007/s12217-015-9479-0  0.066
2010 Bufon CC, González JD, Thurmer DJ, Grimm D, Bauer M, Schmidt OG. Self-assembled ultra-compact energy storage elements based on hybrid nanomembranes. Nano Letters. 10: 2506-10. PMID 20536208 DOI: 10.1021/nl1010367  0.065
2012 Ibrahim I, Bachmatiuk A, Grimm D, Popov A, Makharza S, Knupfer M, Büchner B, Cuniberti G, Rümmeli MH. Understanding high-yield catalyst-free growth of horizontally aligned single-walled carbon nanotubes nucleated by activated C60 species. Acs Nano. 6: 10825-34. PMID 23186015 DOI: 10.1021/Nn304189Y  0.065
2013 Golecki M, Lach J, Jeremies A, Lungwitz F, Fronk M, Salvan G, Zahn DR, Park J, Krupskaya Y, Kataev V, Klingeler R, Büchner B, Mahns B, Knupfer M, Siles PF, ... Grimm D, et al. Chemisorption of exchange-coupled [Ni2L(dppba)]+ complexes on gold by using ambidentate 4-(diphenylphosphino)benzoate co-ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 7787-801. PMID 23595564 DOI: 10.1002/Chem.201300496  0.06
2015 Fisker FY, Grimm D, Wehland M. Third-Generation Beta-Adrenoceptor Antagonists in the Treatment of Hypertension and Heart Failure. Basic & Clinical Pharmacology & Toxicology. 117: 5-14. PMID 25732141 DOI: 10.1111/bcpt.12396  0.058
2014 Grimm D. Animal welfare. Free Willy? Dolphin drama riles aquaria. Science (New York, N.Y.). 344: 1437-8. PMID 24970058 DOI: 10.1126/science.344.6191.1437  0.056
2014 Mohajerin TJ, Neal AW, Telfeyan K, Sasihharan SM, Ford S, Yang N, Chevis DA, Grimm DA, Datta S, White CD, Johannesson KH. Geochemistry of tungsten and arsenic in aquifer systems: A comparative study of groundwaters from west bengal, india, and nevada, usa Water, Air, and Soil Pollution. 225. DOI: 10.1007/S11270-013-1792-X  0.056
2013 Grimm D, Bof Bufon CC, Deneke C, Atkinson P, Thurmer DJ, Schäffel F, Gorantla S, Bachmatiuk A, Schmidt OG. Rolled-up nanomembranes as compact 3D architectures for field effect transistors and fluidic sensing applications. Nano Letters. 13: 213-8. PMID 23245385 DOI: 10.1021/Nl303887B  0.056
2013 Grosse J, Warnke E, Pohl F, Magnusson NE, Wehland M, Infanger M, Eilles C, Grimm D. Impact of sunitinib on human thyroid cancer cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 32: 154-70. PMID 23867310 DOI: 10.1159/000350132  0.055
2013 Grimm D. Growing heterogeneity - Difficult integration | Wachsende Heterogenität - schwierige Integration Merkur. 67: 863-871.  0.055
2013 Woelber L, Grimm D, Vettorazzi E, Wisotzki C, Trillsch F, Jaenicke F, Schwarz J, Choschzick M, Mahner S. Secondary sentinel node biopsy after previous excision of the primary tumor in squamous cell carcinoma of the vulva. Annals of Surgical Oncology. 20: 1701-6. PMID 23132121 DOI: 10.1245/s10434-012-2735-2  0.052
2011 Pearcy CA, Chevis DA, Haug TJ, Jeffries HA, Yang N, Tang J, Grimm DA, Johannesson KH. Evidence of microbially mediated arsenic mobilization from sediments of the Aquia aquifer, Maryland, USA Applied Geochemistry. 26: 575-586. DOI: 10.1016/J.Apgeochem.2011.01.015  0.052
2012 Grimm D. Types of Constitutions The Oxford Handbook of Comparative Constitutional Law. DOI: 10.1093/oxfordhb/9780199578610.013.0006  0.052
2012 Grimm D, Barkhorn I, Festa D, Bonzon K, Boomhower J, Hovland V, Blau J. Assessing catch shares' effects evidence from Federal United States and associated British Columbian fisheries Marine Policy. 36: 644-657. DOI: 10.1016/j.marpol.2011.10.014  0.05
2011 Neurauter ML, Llaneras RE, Grimm D, Green C. Driver Acceptance and Use of a Speed Limit and Curve Advisor Sae International Journal of Passenger Cars - Mechanical Systems. 4: 358-363. DOI: 10.4271/2011-01-0550  0.05
2012 Wehland M, Grosse J, Simonsen U, Infanger M, Bauer J, Grimm D. The effects of newer beta-adrenoceptor antagonists on vascular function in cardiovascular disease. Current Vascular Pharmacology. 10: 378-90. PMID 22022769 DOI: 10.2174/157016112799959323  0.05
2015 Warnke E, Kopp S, Wehland M, Hemmersbach R, Bauer J, Pietsch J, Infanger M, Grimm D. Thyroid Cells Exposed to Simulated Microgravity Conditions – Comparison of the Fast Rotating Clinostat and the Random Positioning Machine Microgravity Science and Technology. DOI: 10.1007/s12217-015-9456-7  0.049
2012 Rastelli A, Ding F, Plumhof JD, Kumar S, Trotta R, Deneke C, Malachias A, Atkinson P, Zallo E, Zander T, Herklotz A, Singh R, Křápek V, Schröter JR, Kiravittaya S, ... ... Grimm D, et al. Controlling quantum dot emission by integration of semiconductor nanomembranes onto piezoelectric actuators Physica Status Solidi (B) Basic Research. 249: 687-696. DOI: 10.1002/Pssb.201100775  0.049
2015 Mueller S, Huard J, Waldow K, Huang X, D'Alessandro LA, Bohl S, Börner K, Grimm D, Klamt S, Klingmüller U, Schilling M. T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes. Molecular Systems Biology. 11: 795. PMID 25771250  0.048
2015 Mueller S, Huard J, Waldow K, Huang X, D'Alessandro LA, Bohl S, Börner K, Grimm D, Klamt S, Klingmüller U, Schilling M. T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes Molecular Systems Biology. 11. DOI: 10.15252/msb.20156032  0.048
2014 Grimm D, Wilson RB, Teshome B, Gorantla S, Rümmeli MH, Bublat T, Zallo E, Li G, Cahill DG, Schmidt OG. Thermal conductivity of mechanically joined semiconducting/metal nanomembrane superlattices. Nano Letters. 14: 2387-93. PMID 24738656 DOI: 10.1021/Nl404827J  0.048
2015 Andersen MB, Simonsen U, Wehland M, Pietsch J, Grimm D. LCZ696 (Valsartan/Sacubitril) - A Possible New Treatment for Hypertension and Heart Failure. Basic & Clinical Pharmacology & Toxicology. PMID 26280447 DOI: 10.1111/bcpt.12453  0.047
2014 Grimm D. Animal research. Male scent may compromise biomedical studies. Science (New York, N.Y.). 344: 461. PMID 24786056 DOI: 10.1126/science.344.6183.461  0.047
2011 Tsafnat G, Setzermann P, Partridge SR, Grimm D. Computational inference of difficult word boundaries in DNA languages Acm International Conference Proceeding Series. DOI: 10.1145/2093698.2093709  0.047
2016 Aleshcheva G, Bauer J, Hemmersbach R, Slumstrup L, Wehland M, Infanger M, Grimm D. Scaffold-free Tissue Formation Under Real and Simulated Microgravity Conditions Basic and Clinical Pharmacology and Toxicology. DOI: 10.1111/bcpt.12561  0.046
2023 Grimm D, Nonnenmacher M. Every little bit helps: A single-residue switch in a vascular AAV enables blood-brain barrier penetration. Molecular Therapy. Methods & Clinical Development. 29: 364-365. PMID 37214312 DOI: 10.1016/j.omtm.2023.04.007  0.045
2014 Grimm D, Woelber L, Trillsch F, Keller-v Amsberg G, Mahner S. Clinical management of epithelial ovarian cancer during pregnancy. European Journal of Cancer (Oxford, England : 1990). 50: 963-71. PMID 24462638 DOI: 10.1016/j.ejca.2013.12.020  0.045
2013 LaRue EA, Grimm D, Thum RA. Laboratory crosses and genetic analysis of natural populations demonstrate sexual viability of invasive hybrid watermilfoils (Myriophyllum spicatum×M. sibiricum) Aquatic Botany. 109: 49-53. DOI: 10.1016/j.aquabot.2013.04.004  0.042
2015 Grimm D. Lower bounds for Pythagoras numbers of function fields Commentarii Mathematici Helvetici. 90: 365-375. DOI: 10.4171/CMH/356  0.042
2012 Sandmire DA, Gorham SR, Rankin NE, Grimm DR. The influence of art making on anxiety: A pilot study Art Therapy. 29: 68-73. DOI: 10.1080/07421656.2012.683748  0.042
2015 Yang N, Welch KA, Mohajerin TJ, Telfeyan K, Chevis DA, Grimm DA, Lyons WB, White CD, Johannesson KH. Comparison of arsenic and molybdenum geochemistry in meromictic lakes of the McMurdo Dry Valleys, Antarctica: Implications for oxyanion-forming trace element behavior in permanently stratified lakes Chemical Geology. 404: 110-125. DOI: 10.1016/J.Chemgeo.2015.03.029  0.041
2015 Sandmire DA, Rankin NE, Gorham SR, Eggleston DT, French CA, Lodge EE, Kuns GC, Grimm DR. Psychological and autonomic effects of art making in college-aged students. Anxiety, Stress, and Coping. 1-9. PMID 26222010 DOI: 10.1080/10615806.2015.1076798  0.04
2015 Grimm D. ANIMAL RESEARCH. Research chimps will soon be listed as 'endangered'. Science (New York, N.Y.). 348: 1296. PMID 26089489 DOI: 10.1126/science.348.6241.1296  0.039
2015 Gianakis A, McNett M, Belle J, Moran C, Grimm D. Risk factors for ventilator-associated pneumonia: among trauma patients with and without brain injury. Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses. 22: 125-31. PMID 25961478 DOI: 10.1097/JTN.0000000000000121  0.038
2013 Grimm D. Splitting fields of conics and sums of squares of rational functions Manuscripta Mathematica. 141: 727-736. DOI: 10.1007/s00229-012-0590-x  0.038
2013 Grimm D. Animal rights. Lawsuits seek 'personhood' for chimpanzees. Science (New York, N.Y.). 342: 1154-5. PMID 24311651 DOI: 10.1126/science.342.6163.1154  0.037
2016 Jalil AR, Chang H, Bandari VK, Robaschik P, Zhang J, Siles PF, Li G, Bürger D, Grimm D, Liu X, Salvan G, Zahn DR, Zhu F, Wang H, Yan D, et al. Fully Integrated Organic Nanocrystal Diode as High Performance Room Temperature NO2 Sensor. Advanced Materials (Deerfield Beach, Fla.). PMID 26890153 DOI: 10.1002/Adma.201506293  0.037
2016 Li G, Grimm D, Engemaier V, Lösch S, Manga K, Bandari VK, Zhu F, Schmidt OG. Hybrid semiconductor/metal nanomembrane superlattices for thermoelectric application Physica Status Solidi (a) Applications and Materials Science. DOI: 10.1002/pssa.201532604  0.037
2010 Grimm D, Thimme R. Risk of HCV transmission via blood products and medical treatment | Übertragungsrisiko von HCV durch blutprodukte und medizinische behandlung Medizinische Welt. 61: 150-154.  0.037
2014 Elizabeth E, Smolen L, Pitts A, Krueger LA, Grimm D. Economic Impact of Converting from Pen and 10-mL Vial to 3-mL Vial for Insulin Delivery in a Hospital Setting. Hospital Pharmacy. 49: 1033-8. PMID 25673892 DOI: 10.1310/hjp4911-1033  0.036
2010 Ulbrich C, Leder A, Pietsch J, Flick B, Wehland M, Grimm D. The impact of vascular endothelial growth factor and basic fibroblast growth factor on cardiac fibroblasts grown under altered gravity conditions Cellular Physiology and Biochemistry. 26: 1011-1022. PMID 21220932 DOI: 10.1159/000323976  0.036
2014 Becher KJ, Grimm D, Van Geel J. Sums of squares in algebraic function fields over a complete discretely valued field Pacific Journal of Mathematics. 267: 257-276. DOI: 10.2140/pjm.2014.267.257  0.036
2022 Maiakovska O, Baumgartl C, Grimm D. Determination of AAV properties by single amino acids: Go(o)d is in the details. Molecular Therapy. Methods & Clinical Development. 27: 93-95. PMID 36212908 DOI: 10.1016/j.omtm.2022.09.006  0.036
2015 Larson S, Grimm D. ANIMAL RIGHTS. The scientist behind the 'personhood' chimps. Science (New York, N.Y.). 348: 1187-8. PMID 26068819 DOI: 10.1126/science.348.6240.1187  0.036
2014 McNett M, Amato S, Gianakis A, Grimm D, Philippbar SA, Belle J, Moran C. The FOUR score and GCS as predictors of outcome after traumatic brain injury. Neurocritical Care. 21: 52-7. PMID 24408147 DOI: 10.1007/s12028-013-9947-6  0.036
2012 Grimm DE, Steiner L, Mautz R. GNSS antenna orientation and detection of multipath signals from direction of arrival 25th International Technical Meeting of the Satellite Division of the Institute of Navigation 2012, Ion Gnss 2012. 2: 1179-1185.  0.035
2015 Ibrahim I, Kalbacova J, Engemaier V, Pang J, Rodriguez RD, Grimm D, Gemming T, Zahn DRT, Schmidt OG, Eckert J, Rümmeli MH. Confirming the Dual Role of Etchants during the Enrichment of Semiconducting Single Wall Carbon Nanotubes by Chemical Vapor Deposition Chemistry of Materials. 27: 5964-5973. DOI: 10.1021/acs.chemmater.5b02037  0.035
2012 Wilczweski P, Grimm D, Gianakis A, Gill B, Sarver W, McNett M. Risk factors associated with pressure ulcer development in critically ill traumatic spinal cord injury patients. Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses. 19: 5-10. PMID 22415500 DOI: 10.1097/JTN.0b013e31823a4528  0.035
2010 Schupp CJ, Holland-Cunz S, Schenk JP, Weisser H, Grimm D, Günther P. Multiple hemangiomas and hemangiomatosis - Risk factors and outcome over an eight year period European Journal of Pediatric Surgery. 20: 379-381. PMID 20665431 DOI: 10.1055/s-0030-1261938  0.034
2011 Grimm D, Mion LC. Falls resulting in traumatic injury among older adults: nursing care issues. Aacn Advanced Critical Care. 22: 161-8. PMID 21521958 DOI: 10.1097/Nci.0B013E3182157Cb3  0.033
2014 Grimm D, Weiss D, Erek K, Zarnekow R. Product carbon footprint and life cycle assessment of ICT - Literature review and state of the art Proceedings of the Annual Hawaii International Conference On System Sciences. 875-884. DOI: 10.1109/HICSS.2014.116  0.032
2022 Ernst L, Steinfeld B, Barayeu U, Klintzsch T, Kurth M, Grimm D, Dick TP, Rebelein JG, Bischofs IB, Keppler F. Methane formation driven by reactive oxygen species across all living organisms. Nature. 603: 482-487. PMID 35264795 DOI: 10.1038/s41586-022-04511-9  0.03
2013 Trillsch F, Ruetzel JD, Herwig U, Doerste U, Woelber L, Grimm D, Choschzick M, Jaenicke F, Mahner S. Surgical management and perioperative morbidity of patients with primary borderline ovarian tumor (BOT). Journal of Ovarian Research. 6: 48. PMID 23837881 DOI: 10.1186/1757-2215-6-48  0.029
2015 Grimm D. The insurgent. Science (New York, N.Y.). 347: 366-9. PMID 25613874 DOI: 10.1126/science.347.6220.366  0.029
2013 Grimm D, Almeda F. Systematics, phylogeny, and biogeography of chaetolepis (melastomataceae) Journal of the Botanical Research Institute of Texas. 7: 217-263.  0.028
2014 Grimm D. Scientific Community. Animal welfare accreditation called into question. Science (New York, N.Y.). 345: 988. PMID 25170127 DOI: 10.1126/science.345.6200.988  0.027
2015 Grimm D. Dawn of the dog. Science (New York, N.Y.). 348: 274-9. PMID 25883337 DOI: 10.1126/science.348.6232.274  0.025
2014 Robaschik P, Siles PF, Bülz D, Richter P, Monecke M, Fronk M, Klyatskaya S, Grimm D, Schmidt OG, Ruben M, Zahn DR, Salvan G. Optical properties and electrical transport of thin films of terbium(III) bis(phthalocyanine) on cobalt. Beilstein Journal of Nanotechnology. 5: 2070-8. PMID 25551034 DOI: 10.3762/bjnano.5.215  0.025
2015 Grimm D. How the wolf became the dog. Science (New York, N.Y.). 348: 277. PMID 25883338 DOI: 10.1126/science.348.6232.277  0.024
2014 Grimm D. Whole community planning: building resiliency at the local level. Journal of Business Continuity & Emergency Planning. 7: 253-9. PMID 24578027  0.023
2015 Grimm D, Assouline B, Piero A. [Schooling of patients exhibiting Autism Spectrum Disorders without mental retardation]. L'Encephale. PMID 26358485 DOI: 10.1016/j.encep.2015.07.005  0.023
2012 Grimm D, Erek K, Wilkens M, Zarnekow R. Towards a production-related Carbon Footprint of IT-services (CFIS) Electronics Goes Green 2012+, Ecg 2012 - Joint International Conference and Exhibition, Proceedings.  0.023
2014 Sharma R, Bufon CCB, Grimm D, Sommer R, Wollatz A, Schadewald J, Thurmer DJ, Siles PF, Bauer M, Schmidt OG. Large-area rolled-up nanomembrane capacitor arrays for electrostatic energy storage Advanced Energy Materials. 4. DOI: 10.1002/aenm.201301631  0.02
2011 Grimm D. Animal cognition. Are dolphins too smart for captivity? Science (New York, N.Y.). 332: 526-9. PMID 21527689 DOI: 10.1126/science.332.6029.526  0.02
2011 Edwards C, Hankey J, Kiefer R, Grimm D, Leask N. Understanding Driver Perceptions of a Vehicle to Vehicle (V2V) Communication System Using a Test Track Demonstration Sae International Journal of Passenger Cars - Mechanical Systems. 4: 444-461. DOI: 10.4271/2011-01-0577  0.018
2015 Grimm D, Hasenburg A, Eulenburg C, Steinsiek L, Mayer S, Eltrop S, Prieske K, Trillsch F, Mahner S, Woelber L. Sexual Activity and Function in Patients With Gynecological Malignancies After Completed Treatment. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 25: 1134-41. PMID 26098093 DOI: 10.1097/IGC.0000000000000468  0.018
2015 Cocemasov AI, Nika DL, Fomin VM, Grimm D, Schmidt OG. Phonon-engineered thermal transport in Si wires with constant and periodically modulated cross-sections: A crossover between nano- and microscale regimes Applied Physics Letters. 107. DOI: 10.1063/1.4926401  0.017
2015 Grimm D. The role of fundamental rights after sixty-five years of constitutional jurisprudence in Germany International Journal of Constitutional Law. 13: 9-29. DOI: 10.1093/icon/mov005  0.016
2013 Grimm D, Erek K, Zarnekow R. Carbon footprint of IT-Services - A comparative study of energy consumption for offline and online storage usage 19th Americas Conference On Information Systems, Amcis 2013 - Hyperconnected World: Anything, Anywhere, Anytime. 1: 666-677.  0.016
2011 Bai F, Grimm D, Talty T, Saraydar C. Gossip Networks: The Enabler for Sparsely Populated VANETs Sae International Journal of Passenger Cars - Electronic and Electrical Systems. 4: 1-9. DOI: 10.4271/2011-01-0046  0.015
2015 Grimm D, Eulenburg C, Brummer O, Schliedermann AK, Trillsch F, Prieske K, Gieseking F, Selka E, Mahner S, Woelber L. Sexual activity and function after surgical treatment in patients with (pre)invasive vulvar lesions. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. PMID 26094599 DOI: 10.1007/s00520-015-2812-8  0.015
2015 Anken R, Brungs S, Grimm D, Knie M, Hilbig R. Fish Inner Ear Otolith Growth Under Real Microgravity (Spaceflight) and Clinorotation Microgravity Science and Technology. DOI: 10.1007/s12217-015-9459-4  0.015
2016 Woelber L, Eulenburg C, Grimm D, Trillsch F, Bohlmann I, Burandt E, Dieckmann J, Klutmann S, Schmalfeldt B, Mahner S, Prieske K. The Risk of Contralateral Non-sentinel Metastasis in Patients with Primary Vulvar Cancer and Unilaterally Positive Sentinel Node Annals of Surgical Oncology. 1-7. DOI: 10.1245/s10434-016-5114-6  0.014
2011 Grimm D. Plea for impact research | Plädoyer für Wirkungsforschung Rechtsgeschichte. 19: 97-105.  0.014
2015 Grimm D. The Democratic Costs of Constitutionalisation: The European Case European Law Journal. 21: 460-473. DOI: 10.1111/eulj.12139  0.012
2013 Bordes JL, Favre JL, Grimm D. Jean Biarez: His Life and Work Multiscale Geomechanics. 1-14. DOI: 10.1002/9781118601433.ch1  0.01
2024 Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, ... ... Grimm D, et al. Loss of epigenetic information as a cause of mammalian aging. Cell. 187: 1312-1313. PMID 38428398 DOI: 10.1016/j.cell.2024.01.049  0.01
2015 Grimm D. Why we outlive our pets Science. 350: 1182-1185. PMID 26785473  0.01
2015 Medas JC, Amato S, Grimm D, Radziewicz R, Rhodes C, VanHorn C, McNett M. Outcomes of a comprehensive nurse residency program. Nursing Management. 46: 40-8. PMID 26492506 DOI: 10.1097/01.NUMA.0000469353.71942.5b  0.01
2015 Wölber L, Mahner S, Grimm D, Trillsch F, Prieske K. Lymphadenectomy for vulvar cancer | Lymphonodektomie beim Vulvakarzinom Gynakologe. 48: 741-752. DOI: 10.1007/s00129-015-3775-z  0.01
2015 Grimm D, Beaud O. Démocratie européenne : Les raisons de la défiance Esprit. 83-94.  0.01
2015 Grimm D. Diagnosis and treatment: Ovarian can European Journal of Oncology Pharmacy. 9: 6.  0.01
2014 Siles PF, Bufon CCB, Grimm D, Jalil AR, Mende C, Lungwitz F, Salvan G, Zahn DRT, Lang H, Schmidt OG. Morphology and local transport characteristics of metalloporphyrin thin films Organic Electronics: Physics, Materials, Applications. 15: 1432-1439. DOI: 10.1016/j.orgel.2014.04.004  0.01
2013 Bode JP, Grimm D, Kemnitz A. Hypercube-anti-ramsey numbers of Q5 Ars Combinatoria. 110: 105-111.  0.01
2011 Grimm D. Are dolphins too smart for captivity? (Science (526)) Science. 333: 698. DOI: 10.1126/science.333.6043.698  0.01
2011 Grimm D. Was the German empirea sovereign state? Imperial Germany Revisited: Continuing Debates and New Perspectives. 51-66.  0.01
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