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Kevin B Dagbay - Publications

Affiliations: 
University of Massachusetts, Amherst, Amherst, MA 
Area:
Protein Engineering, Cysteine Protease, Drug Discovery
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Martin CJ, Datta A, Littlefield C, Kalra A, Chapron C, Wawersik S, Dagbay KB, Brueckner CT, Nikiforov A, Danehy FT, Streich FC, Boston C, Simpson A, Jackson JW, Lin S, et al. Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape. Science Translational Medicine. 12. PMID 32213632 DOI: 10.1126/Scitranslmed.Aay8456  0.318
2020 Dagbay KB, Treece E, Streich FC, Jackson JW, Faucette RR, Nikiforov A, Lin SC, Boston CJ, Nicholls SB, Capili AD, Carven GJ. Structural basis for specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015. The Journal of Biological Chemistry. PMID 32075906 DOI: 10.1074/Jbc.Ra119.012293  0.711
2019 Okerberg ES, Dagbay KB, Green JL, Soni I, Aban A, Nomanbhoy TK, Savinov SN, Hardy JA, Kozarich JW. Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP-Binding Site at the Dimer Interface of Procaspase-6. Biochemistry. PMID 31095371 DOI: 10.1021/Acs.Biochem.9B00290  0.649
2018 Eron SJ, MacPherson DJ, Dagbay KB, Hardy JA. Multiple mechanisms of zinc-mediated inhibition for the apoptotic caspases -3, -6, -7, & -8. Acs Chemical Biology. PMID 29364645 DOI: 10.1021/Acschembio.8B00064  0.729
2017 Dagbay KB, Hardy JA. Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions. Proceedings of the National Academy of Sciences of the United States of America. PMID 28864531 DOI: 10.1073/Pnas.1704640114  0.658
2017 Dagbay KB, Hill ME, Barrett E, Hardy JA. Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency. Biochemistry. PMID 28726391 DOI: 10.1021/Acs.Biochem.7B00357  0.756
2017 Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Caspase-6 Undergoes a Distinct Helix-Strand Interconversion Upon Substrate Binding. The Journal of Biological Chemistry. PMID 28154009 DOI: 10.1074/Jbc.M116.773499  0.748
2014 Dagbay K, Eron SJ, Serrano BP, Velázquez-Delgado EM, Zhao Y, Lin D, Vaidya S, Hardy JA. A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases. Methods in Enzymology. 544: 215-49. PMID 24974292 DOI: 10.1016/B978-0-12-417158-9.00009-1  0.43
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