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Charles J. Walsby, Ph.D. - Publications

Affiliations: 
Chemistry Simon Fraser University, Burnaby, British Columbia, Canada 
Area:
Bioinorganic chemistry, spectroscopy
Website:
http://www.sfu.ca/chemistry/groups/walsby/Charles_Walsby.htm
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nguyen BX, VandeVen W, MacNeil GA, Zhou W, Paterson AR, Walsby CJ, Chiang L. High-Valent Ni and Cu Complexes of a Tetraanionic Bis(amidateanilido) Ligand. Inorganic Chemistry. 62: 15180-15194. PMID 37676794 DOI: 10.1021/acs.inorgchem.3c02358  0.316
2023 MacNeil GA, Chang SW, Prosser KE, Ye E, Heroux D, Lewis AR, Bally M, Walsby CJ. Spatial characterization of redox processes and speciation of Ru(III) anticancer complexes by F magnetic resonance imaging. Chemical Communications (Cambridge, England). 59: 623-626. PMID 36537324 DOI: 10.1039/d2cc04830b  0.705
2022 Schrage BR, Zhou W, Harrison LA, Nevonen DE, Thompson JR, Prosser KE, Walsby CJ, Ziegler CJ, Leznoff DB, Nemykin VN. Resolving a Half-Century-Long Controversy between (Magneto)optical and EPR Spectra of Single-Electron-Reduced [PcFe], [PcFeL], and [PcFeX] Complexes: Story of a Double Flip. Inorganic Chemistry. PMID 36472380 DOI: 10.1021/acs.inorgchem.2c03456  0.727
2021 Walsby CJ, Prosser KE, Xie D, Chu A, MacNeil GA, Varju BR, Kadakia RT, Que EL. Copper(II) Pyridyl Amino-Phenolates: Hypoxia-Selective, Nucleus Targeting Cytotoxins, and Magnetic Resonance Probes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33878230 DOI: 10.1002/chem.202100603  0.753
2020 Elsayed SA, Harrypersad S, Sahyon HA, El-Magd MA, Walsby CJ. Ruthenium(II)/(III) DMSO-Based Complexes of 2-Aminophenyl Benzimidazole with In Vitro and In Vivo Anticancer Activity. Molecules (Basel, Switzerland). 25. PMID 32962014 DOI: 10.3390/Molecules25184284  0.43
2019 Gomes LMF, Bataglioli JC, Jussila AJ, Smith JR, Walsby CJ, Storr T. Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes. Frontiers in Chemistry. 7: 838. PMID 31921764 DOI: 10.3389/Fchem.2019.00838  0.347
2019 Safaei E, Balaghi SE, Chiang L, Clarke RM, Martelino D, Webb MI, Wong EWY, Savard D, Walsby CJ, Storr T. Stabilization of different redox levels of a tridentate benzoxazole amidophenoxide ligand when bound to Co(iii) or V(v). Dalton Transactions (Cambridge, England : 2003). PMID 31429839 DOI: 10.1039/C9Dt02865J  0.701
2019 Gomes LMF, Mahammed A, Prosser KE, Smith JR, Silverman MA, Walsby CJ, Gross Z, Storr T. A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation. Chemical Science. 10: 1634-1643. PMID 30842826 DOI: 10.1039/C8Sc04660C  0.724
2018 Mu C, Prosser KE, Harrypersad S, MacNeil GA, Panchmatia R, Thompson JR, Sinha S, Warren JJ, Walsby CJ. Activation by Oxidation: Ferrocene-Functionalized Ru(II)-Arene Complexes with Anticancer, Antibacterial, and Antioxidant Properties. Inorganic Chemistry. PMID 30495936 DOI: 10.1021/Acs.Inorgchem.8B02542  0.754
2018 Prosser KE, Leung A, Harrypersad S, Lewis AR, Bally MB, Walsby CJ. Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29490115 DOI: 10.1002/Chem.201800289  0.716
2018 Zhang C, Sutherland M, Herasymchuk K, Clarke RM, Thompson JR, Chiang L, Walsby CJ, Storr T. Octahedral Co(III) salen complexes: the role of peripheral ligand electronics on axial ligand release upon reduction Canadian Journal of Chemistry. 96: 110-118. DOI: 10.1139/Cjc-2017-0277  0.471
2016 Stott LA, Prosser KE, Berdichevsky EK, Walsby CJ, Warren JJ. Lowering water oxidation overpotentials using the ionisable imidazole of copper(2-(2'-pyridyl)imidazole). Chemical Communications (Cambridge, England). PMID 27990513 DOI: 10.1039/C6Cc09208J  0.702
2016 Prosser KE, Chang SW, Saraci F, Le PH, Walsby CJ. Anticancer copper pyridine benzimidazole complexes: ROS generation, biomolecule interactions, and cytotoxicity. Journal of Inorganic Biochemistry. 167: 89-99. PMID 27915178 DOI: 10.1016/J.Jinorgbio.2016.11.006  0.771
2016 Zhao J, Prosser KE, Chang SW, Zakharia SP, Walsby CJ. Combining a Ru(ii)-arene complex with a NO-releasing nitrate-ester ligand generates cytotoxic activity. Dalton Transactions (Cambridge, England : 2003). PMID 27805196 DOI: 10.1039/C6Dt03661A  0.748
2016 Chang SW, Lewis AR, Prosser KE, Thompson JR, Gladkikh M, Bally MB, Warren JJ, Walsby CJ. CF3 Derivatives of the Anticancer Ru(III) Complexes KP1019, NKP-1339, and Their Imidazole and Pyridine Analogues Show Enhanced Lipophilicity, Albumin Interactions, and Cytotoxicity. Inorganic Chemistry. PMID 27143338 DOI: 10.1021/Acs.Inorgchem.6B00359  0.772
2016 Bonanno NM, Lough AJ, Prosser KE, Walsby CJ, Poddutoori PK, Lemaire MT. A stable open-shell redox active ditopic ligand. Dalton Transactions (Cambridge, England : 2003). 45: 5460-3. PMID 26966736 DOI: 10.1039/C5Dt04061B  0.729
2016 Leung AWY, Anantha M, Prosser KE, Wehbe M, Walsby CJ, Bally MB. Abstract 1319: A novel formulation of CX-5461, a small-molecule inhibitor of rRNA synthesis, and its use for treatment of acute myeloid leukemia models Cancer Research. 76: 1319-1319. DOI: 10.1158/1538-7445.Am2016-1319  0.678
2016 Prosser KE, Walsby CJ. Electron Paramagnetic Resonance as a Tool for Studying the Mechanisms of Paramagnetic Anticancer Metallodrugs European Journal of Inorganic Chemistry. 2017: 1573-1585. DOI: 10.1002/Ejic.201601142  0.76
2015 Mu C, Chang SW, Prosser KE, Leung AW, Santacruz S, Jang T, Thompson JR, Yapp DT, Warren JJ, Bally MB, Beischlag TV, Walsby CJ. Induction of Cytotoxicity in Pyridine Analogues of the Anti-metastatic Ru(III) Complex NAMI-A by Ferrocene Functionalization. Inorganic Chemistry. PMID 26652771 DOI: 10.1021/Acs.Inorgchem.5B02109  0.777
2015 Webb MI, Walsby CJ. Albumin binding and ligand-exchange processes of the Ru(iii) anticancer agent NAMI-A and its bis-DMSO analogue determined by ENDOR spectroscopy. Dalton Transactions (Cambridge, England : 2003). PMID 26174110 DOI: 10.1039/C5Dt02021B  0.725
2015 Jones MR, Mu C, Wang MC, Webb MI, Walsby CJ, Storr T. Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity. Metallomics : Integrated Biometal Science. 7: 129-35. PMID 25387614 DOI: 10.1039/C4Mt00252K  0.613
2014 Makins C, Whitelaw DA, Mu C, Walsby CJ, Wolthers KR. Isotope effects for deuterium transfer and mutagenesis of Tyr187 provide insight into controlled radical chemistry in adenosylcobalamin-dependent ornithine 4,5-aminomutase. Biochemistry. 53: 5432-43. PMID 25100213 DOI: 10.1021/Bi5006706  0.311
2014 Lo SY, Säbel CE, Webb MI, Walsby CJ, Siemann S. High metal substitution tolerance of anthrax lethal factor and characterization of its active copper-substituted analogue. Journal of Inorganic Biochemistry. 140: 12-22. PMID 25042732 DOI: 10.1016/J.Jinorgbio.2014.06.009  0.663
2013 Webb MI, Wu B, Jang T, Chard RA, Wong EW, Wong MQ, Yapp DT, Walsby CJ. Increasing the bioavailability of Ru(III) anticancer complexes through hydrophobic albumin interactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 17031-42. PMID 24203647 DOI: 10.1002/Chem.201302671  0.719
2013 Webb MI, Walsby CJ. EPR as a probe of the intracellular speciation of ruthenium(III) anticancer compounds. Metallomics : Integrated Biometal Science. 5: 1624-33. PMID 24057014 DOI: 10.1039/C3Mt00090G  0.684
2012 Wong EW, Miura A, Wright MD, He Q, Walsby CJ, Shimizu S, Kobayashi N, Leznoff DB. Gold(II) phthalocyanine revisited: synthesis and spectroscopic properties of gold(III) phthalocyanine and an unprecedented ring-contracted phthalocyanine analogue. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12404-10. PMID 22933175 DOI: 10.1002/Chem.201201701  0.378
2012 Simmons JM, Yildirim T, Hamaed A, Antonelli DM, Webb MI, Walsby CJ. Direct observation of activated hydrogen binding to a supported organometallic compound at room temperature. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 4170-3. PMID 22392791 DOI: 10.1002/Chem.201102658  0.617
2012 Webb MI, Chard RA, Al-Jobory YM, Jones MR, Wong EW, Walsby CJ. Pyridine analogues of the antimetastatic Ru(III) complex NAMI-A targeting non-covalent interactions with albumin. Inorganic Chemistry. 51: 954-66. PMID 22224431 DOI: 10.1021/Ic202029E  0.723
2012 Wong EWY, Miura A, Wright MD, He Q, Walsby CJ, Shimizu S, Kobayashi N, Leznoff DB. Inside Cover: Gold(II) Phthalocyanine Revisited: Synthesis and Spectroscopic Properties of Gold(III) Phthalocyanine and an Unprecedented Ring-Contracted Phthalocyanine Analogue (Chem. Eur. J. 39/2012) Chemistry - a European Journal. 18: 12158-12158. DOI: 10.1002/Chem.201290168  0.305
2011 Webb MI, Walsby CJ. Control of ligand-exchange processes and the oxidation state of the antimetastatic Ru(III) complex NAMI-A by interactions with human serum albumin. Dalton Transactions (Cambridge, England : 2003). 40: 1322-31. PMID 21210063 DOI: 10.1039/C0Dt01168A  0.729
2011 Sherren CN, Mu C, Webb MI, McKenzie I, McCollum BM, Brodovitch JC, Percival PW, Storr T, Seddon KR, Clyburne JAC, Walsby CJ. Merging the chemistry of electron-rich olefins with imidazolium ionic liquids: Radicals and hydrogen-atom adducts Chemical Science. 2: 2173-2177. DOI: 10.1039/C1Sc00408E  0.622
2010 Hoang TK, Webb MI, Mai HV, Hamaed A, Walsby CJ, Trudeau M, Antonelli DM. Design and synthesis of vanadium hydrazide gels for Kubas-type hydrogen adsorption: a new class of hydrogen storage materials. Journal of the American Chemical Society. 132: 11792-8. PMID 20681605 DOI: 10.1021/Ja104926H  0.604
2010 Wong EW, Walsby CJ, Storr T, Leznoff DB. Phthalocyanine as a chemically inert, redox-active ligand: structural and electronic properties of a Nb(IV)-oxo complex incorporating a highly reduced phthalocyanine(4-) anion. Inorganic Chemistry. 49: 3343-50. PMID 20225871 DOI: 10.1021/Ic902409N  0.411
2010 Cetinbas N, Webb MI, Dubland JA, Walsby CJ. Serum-protein interactions with anticancer Ru(III) complexes KP1019 and KP418 characterized by EPR. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 131-45. PMID 19707803 DOI: 10.1007/S00775-009-0578-5  0.699
2008 Ramnial T, Taylor SA, Bender ML, Gorodetsky B, Lee PT, Dickie DA, McCollum BM, Pye CC, Walsby CJ, Clyburne JA. Carbon-centered strong bases in phosphonium ionic liquids. The Journal of Organic Chemistry. 73: 801-12. PMID 18173280 DOI: 10.1021/Jo701289D  0.327
2008 Dickie DA, Macintosh IS, Ino DD, He Q, Labeodan OA, Jennings MC, Schatte G, Walsby CJ, Clyburne JAC. Synthesis of the bulky m-terphenyl phenol Ar*OH (Ar* = C 6H3-2,6-Mes2, Mes = 2,4,6-trimethylphenyl) and the preparation and structural characterization of several of its metal complexes Canadian Journal of Chemistry. 86: 20-31. DOI: 10.1139/V07-131  0.34
2006 Lees NS, Chen D, Walsby CJ, Behshad E, Frey PA, Hoffman BM. How an enzyme tames reactive intermediates: positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy. Journal of the American Chemical Society. 128: 10145-54. PMID 16881644 DOI: 10.1021/Ja061282R  0.442
2005 Walsby CJ, Telser J, Rigsby RE, Armstrong RN, Hoffman BM. Enzyme control of small-molecule coordination in FosA as revealed by 31P pulsed ENDOR and ESE-EPR. Journal of the American Chemical Society. 127: 8310-9. PMID 15941264 DOI: 10.1021/Ja044094E  0.651
2005 Walsby CJ, Ortillo D, Yang J, Nnyepi MR, Broderick WE, Hoffman BM, Broderick JB. Spectroscopic approaches to elucidating novel iron-sulfur chemistry in the "radical-Sam" protein superfamily. Inorganic Chemistry. 44: 727-41. PMID 15859242 DOI: 10.1021/Ic0484811  0.48
2003 Chen D, Walsby C, Hoffman BM, Frey PA. Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase. Journal of the American Chemical Society. 125: 11788-9. PMID 14505379 DOI: 10.1021/Ja036120Z  0.478
2003 Walsby CJ, Krepkiy D, Petering DH, Hoffman BM. Cobalt-substituted zinc finger 3 of transcription factor IIIA: interactions with cognate DNA detected by (31)P ENDOR spectroscopy. Journal of the American Chemical Society. 125: 7502-3. PMID 12812475 DOI: 10.1021/Ja034589O  0.5
2003 Broderick JB, Ortillo D, Broderick WE, Hong W, Walsby CJ, Hoffman BM, Krebs C, Hanh B. Poised for radical generation: Interaction of S-adenosylmethionine with a [4Fe4S] cluster Journal of Inorganic Biochemistry. 96: 104. DOI: 10.1016/S0162-0134(03)80571-8  0.417
2003 Petering DH, Krepkiy D, Forsterling H, Walsby CJ, Hoffman B. Structure, DNA binding, and comparative properties of zinc, cadmium, lead, and cobalt finger-3 peptides from Xenopus laevis transcription factor IIIA Journal of Inorganic Biochemistry. 96: 73. DOI: 10.1016/S0162-0134(03)80527-5  0.439
2002 Walsby CJ, Ortillo D, Broderick WE, Broderick JB, Hoffman BM. An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme. Journal of the American Chemical Society. 124: 11270-1. PMID 12236732 DOI: 10.1021/Ja027078V  0.451
2002 Walsby CJ, Hong W, Broderick WE, Cheek J, Ortillo D, Broderick JB, Hoffman BM. Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme. Journal of the American Chemical Society. 124: 3143-51. PMID 11902903 DOI: 10.1021/Ja012034S  0.489
2000 Gaponenko V, Dvoretsky A, Walsby C, Hoffman BM, Rosevear PR. Calculation of z-coordinates and orientational restraints using a metal binding tag Biochemistry. 39: 15217-15224. PMID 11106501 DOI: 10.1021/Bi001381W  0.511
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