Philippe F. Moullier, M.D. and Ph.D. - Publications

Affiliations: 
Université de Nantes INSERM - France 
Area:
Gene Therapy

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mével M, Pichard V, Bouzelha M, Alvarez-Dorta D, Lalys PA, Provost N, Allais M, Mendes A, Landagaray E, Ducloyer JB, Toublanc E, Galy A, Brument N, Lefevre GM, Gouin SG, ... ... Moullier P, et al. Mannose-coupled AAV2: A second-generation AAV vector for increased retinal gene therapy efficiency. Molecular Therapy. Methods & Clinical Development. 32: 101187. PMID 38327809 DOI: 10.1016/j.omtm.2024.101187  0.341
2021 Gernoux G, Guilbaud M, Devaux M, Journou M, Pichard V, Jaulin N, Léger A, Le Duff J, Deschamps JY, Le Guiner C, Moullier P, Cherel Y, Adjali O. AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation. Molecular Therapy. Methods & Clinical Development. 20: 660-674. PMID 33718516 DOI: 10.1016/j.omtm.2021.02.003  0.349
2020 Bey K, Deniaud J, Dubreil L, Joussemet B, Cristini J, Ciron C, Hordeaux J, Le Boulc'h M, Marche K, Maquigneau M, Guilbaud M, Moreau R, Larcher T, Deschamps JY, Fusellier M, ... ... Moullier P, et al. Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases? Molecular Therapy. Methods & Clinical Development. 17: 771-784. PMID 32355866 DOI: 10.1016/J.Omtm.2020.04.001  0.408
2020 Vandamme C, Xicluna R, Hesnard L, Devaux M, Jaulin N, Guilbaud M, Duff JL, Couzinié C, Moullier P, Saulquin X, Adjali O. Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation. Frontiers in Immunology. 10: 3110. PMID 32038634 DOI: 10.3389/Fimmu.2019.03110  0.313
2020 Bertin B, Veron P, Leborgne C, Deschamps JY, Moullec S, Fromes Y, Collaud F, Boutin S, Latournerie V, van Wittenberghe L, Delache B, Le Grand R, Dereuddre-Bosquet N, Benveniste O, Moullier P, et al. Capsid-specific removal of circulating antibodies to adeno-associated virus vectors. Scientific Reports. 10: 864. PMID 31965041 DOI: 10.1038/S41598-020-57893-Z  0.331
2020 Mével M, Bouzelha M, Leray A, Pacouret S, Guilbaud M, Penaud-Budloo M, Alvarez-Dorta D, Dubreil L, Gouin SG, Combal JP, Hommel M, Gonzalez-Aseguinolaza G, Blouin V, Moullier P, Adjali O, et al. Chemical modification of the adeno-associated virus capsid to improve gene delivery Chemical Science. 11: 1122-1131. DOI: 10.1039/C9Sc04189C  0.393
2019 Guilbaud M, Devaux M, Couzinié C, Duff JL, Toromanoff A, Vandamme C, Jaulin N, Gernoux G, Larcher T, Moullier P, Guiner CL, Adjali O. 5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity Human Gene Therapy. PMID 30808235 DOI: 10.1089/Hum.2018.234  0.436
2018 François A, Bouzelha M, Lecomte E, Broucque F, Penaud-Budloo M, Adjali O, Moullier P, Blouin V, Ayuso E. Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls. Molecular Therapy. Methods & Clinical Development. 10: 223-236. PMID 30112419 DOI: 10.1016/J.Omtm.2018.07.004  0.354
2018 Domenger C, Allais M, François V, Léger A, Lecomte E, Montus M, Servais L, Voit T, Moullier P, Audic Y, Le Guiner C. RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect. Molecular Therapy. Nucleic Acids. 10: 277-291. PMID 29499940 DOI: 10.1016/J.Omtn.2017.12.008  0.344
2017 Le Meur G, Lebranchu P, Billaud F, Adjali O, Schmitt S, Bézieau S, Péréon Y, Valabregue R, Ivan C, Darmon C, Moullier P, Rolling F, Weber M. Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29033008 DOI: 10.1016/J.Ymthe.2017.09.014  0.36
2017 Le Guiner C, Servais L, Montus M, Larcher T, Fraysse B, Moullec S, Allais M, François V, Dutilleul M, Malerba A, Koo T, Thibaut JL, Matot B, Devaux M, Le Duff J, ... ... Moullier P, et al. Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy. Nature Communications. 8: 16105. PMID 28742067 DOI: 10.1038/Ncomms16105  0.468
2017 Penaud-Budloo M, Lecomte E, Guy-Duché A, Saleun S, Roulet A, Lopez-Roques C, Tournaire B, Cogné B, Léger A, Blouin V, Lindenbaum P, Moullier P, Ayuso E. Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells Human Gene Therapy Methods. 28: 148-162. PMID 28463571 DOI: 10.1089/Hgtb.2016.185  0.341
2017 Pacouret S, Bouzelha M, Shelke R, Andres-Mateos E, Xiao R, Maurer A, Mevel M, Turunen H, Barungi T, Penaud-Budloo M, Broucque F, Blouin V, Moullier P, Ayuso E, Vandenberghe LH. AAV-ID: a Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28427840 DOI: 10.1016/J.Ymthe.2017.04.001  0.355
2016 Tshilenge KT, Ameline B, Weber M, Mendes-Madeira A, Nedellec S, Biget M, Provost N, Libeau L, Blouin V, Deschamps JY, Le Meur G, Colle MA, Moullier P, Pichard V, Rolling F. Vitrectomy prior to intravitreal injection of AAV2/2 vector promotes efficient transduction of retinal ganglion cells in dogs and non-human primates. Human Gene Therapy Methods. PMID 27229628 DOI: 10.1089/Hgtb.2016.034  0.387
2016 D'Costa S, Blouin V, Broucque F, Penaud-Budloo M, François A, Perez IC, Le Bec C, Moullier P, Snyder RO, Ayuso E. Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR. Molecular Therapy. Methods & Clinical Development. 5: 16019. PMID 27069952 DOI: 10.1038/Mtm.2016.19  0.384
2016 Pichard V, Provost N, Mendes-Madeira A, Libeau L, Hulin P, Tshilenge KT, Biget M, Ameline B, Deschamps JY, Weber M, Le Meur G, Colle MA, Moullier P, Rolling F. AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 867-76. PMID 26857842 DOI: 10.1038/Mt.2016.37  0.401
2016 Neuberger EW, Perez I, Le Guiner C, Moser D, Ehlert T, Allais M, Moullier P, Simon P, Snyder RO. Establishment of two quantitative nested qPCR assays targeting the human EPO transgene. Gene Therapy. 23: 330-9. PMID 26752352 DOI: 10.1038/Gt.2016.2  0.361
2016 Vandamme C, Devaux M, Jaulin N, Guilbaud M, Duff JL, Hesnard L, Djamai H, Bonneville M, Moullier P, Saulquin X, Adjali O. 697. Phenotypic and Functional Characterisation of Human Anti-AAV CD8+ T Cells Using MHC Class I Tetramer-Associated Magnetic Enrichment Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33505-5  0.333
2016 Guiner CL, Servais L, Montus M, Larcher T, Fraysse B, Moullec S, Koo T, Malerba A, Bec CL, Hebben M, Masurier C, Mingozzi F, Adjali O, Carlier P, Hogrel J, ... ... Moullier P, et al. 503. Adeno-Associated Virus Vector (AAV) Microdystrophin Gene Therapy Prolongs Survival and Restores Muscle Function in the Canine Model of Duchenne Muscular Dystrophy (DMD) Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33312-3  0.464
2016 Dupont J, Tournaire B, Durand R, Marolleau B, Bertil E, Georger C, Lecomte E, Cogné B, Gjata B, vanWittenberghe L, Vignaud A, Snyder RO, Moullier P, Léger A. 390. Impact of a Treatment with Antioxidant on Gene Transfer Efficiency After Recombinant Adeno-Associated Vector Injection in a Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33199-9  0.46
2016 Pacouret S, Mevel M, Bouzelha M, Maurer A, Shelke R, Xiao R, Penaud-Budloo M, Turunen H, Broucque F, Blouin V, Moullier P, Ayuso E, Vandenberghe LH. 34. Development and Validation of Identity and Homogeneity Assays for AAV Preparations Molecular Therapy. 24: S15. DOI: 10.1016/S1525-0016(16)32843-X  0.374
2015 Lecomte E, Tournaire B, Cogné B, Dupont JB, Lindenbaum P, Martin-Fontaine M, Broucque F, Robin C, Hebben M, Merten OW, Blouin V, François A, Redon R, Moullier P, Léger A. Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing. Molecular Therapy. Nucleic Acids. 4: e260. PMID 26506038 DOI: 10.1038/Mtna.2015.32  0.364
2015 Guan X, Wang Z, Czerniecki S, Mack D, François V, Blouin V, Moullier P, Childers M. Use of adeno-associated virus to enrich cardiomyocytes derived from human stem cells. Human Gene Therapy. Clinical Development. PMID 26177370 DOI: 10.1089/Hum.2015.052  0.351
2015 Dupont JB, Tournaire B, Georger C, Marolleau B, Jeanson-Leh L, Ledevin M, Lindenbaum P, Lecomte E, Cogné B, Dubreil L, Larcher T, Gjata B, Van Wittenberghe L, Le Guiner C, Penaud-Budloo M, ... ... Moullier P, et al. Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA. Molecular Therapy. Methods & Clinical Development. 2: 15010. PMID 26029721 DOI: 10.1038/Mtm.2015.10  0.368
2015 Zerah M, Piguet F, Colle MA, Raoul S, Deschamps JY, Deniaud J, Gautier B, Toulgoat F, Bieche I, Laurendeau I, Sondhi D, Souweidane MM, Cartier-Lacave N, Moullier P, Crystal RG, et al. Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates. Human Gene Therapy. Clinical Development. 26: 113-24. PMID 25758611 DOI: 10.1089/Humc.2014.139  0.425
2015 Hordeaux J, Dubreil L, Deniaud J, Iacobelli F, Moreau S, Ledevin M, Le Guiner C, Blouin V, Le Duff J, Mendes-Madeira A, Rolling F, Cherel Y, Moullier P, Colle MA. Efficient central nervous system AAVrh10-mediated intrathecal gene transfer in adult and neonate rats. Gene Therapy. 22: 316-24. PMID 25588740 DOI: 10.1038/Gt.2014.121  0.315
2015 Domenger C, Lardenois A, Allais M, François V, Montus M, Servais L, Voit T, Moullier P, Guiner CL. 143. Off-Target Analysis of a rAAV-U7snRNA Vector Used for the Treatment of Duchenne Patients By Exon Skipping Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33748-0  0.409
2015 Guiner CL, Servais L, Montus M, Bodvael F, Gjata B, Hogrel JY, Carlier P, Moullec S, Masurier C, Adjali O, Mingozzi F, Koo T, Athanasopoulos T, Cherel Y, Mavilio F, ... ... Moullier P, et al. Adeno-associated virus vector (AAV) microdystrophin gene therapy prolongs survival and restores muscle function in the canine model of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 25. DOI: 10.1016/J.Nmd.2015.06.458  0.415
2014 Moreau A, Vandamme C, Segovia M, Devaux M, Guilbaud M, Tilly G, Jaulin N, Le Duff J, Cherel Y, Deschamps JY, Anegon I, Moullier P, Cuturi MC, Adjali O. Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer. Molecular Therapy. Methods & Clinical Development. 1: 14028. PMID 26015970 DOI: 10.1038/Mtm.2014.28  0.454
2014 Ayuso E, Blouin V, Lock M, McGorray S, Leon X, Alvira MR, Auricchio A, Bucher S, Chtarto A, Clark KR, Darmon C, Doria M, Fountain W, Gao G, Gao K, ... ... Moullier P, et al. Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material. Human Gene Therapy. 25: 977-87. PMID 25275822 DOI: 10.1089/Hum.2014.057  0.354
2014 Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, Guigand L, Cherel Y, Moullier P, Rolling F, Adjali O. Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates. Plos One. 9: e102538. PMID 25248159 DOI: 10.1371/Journal.Pone.0102538  0.44
2014 Le Guiner C, Montus M, Servais L, Cherel Y, Francois V, Thibaud JL, Wary C, Matot B, Larcher T, Guigand L, Dutilleul M, Domenger C, Allais M, Beuvin M, Moraux A, ... ... Moullier P, et al. Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1923-35. PMID 25200009 DOI: 10.1038/Mt.2014.151  0.38
2014 Chuah MK, Petrus I, De Bleser P, Le Guiner C, Gernoux G, Adjali O, Nair N, Willems J, Evens H, Rincon MY, Matrai J, Di Matteo M, Samara-Kuko E, Yan B, Acosta-Sanchez A, ... ... Moullier P, et al. Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1605-13. PMID 24954473 DOI: 10.1038/Mt.2014.114  0.426
2014 Bucher T, Dubreil L, Colle MA, Maquigneau M, Deniaud J, Ledevin M, Moullier P, Joussemet B. Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats. Gene Therapy. 21: 522-8. PMID 24572783 DOI: 10.1038/Gt.2014.16  0.333
2014 Childers MK, Joubert R, Poulard K, Moal C, Grange RW, Doering JA, Lawlor MW, Rider BE, Jamet T, Danièle N, Martin S, Rivière C, Soker T, Hammer C, Van Wittenberghe L, ... ... Moullier P, et al. Gene therapy prolongs survival and restores function in murine and canine models of myotubular myopathy. Science Translational Medicine. 6: 220ra10. PMID 24452262 DOI: 10.1126/Scitranslmed.3007523  0.462
2014 Lhériteau E, Petit L, Weber M, Le Meur G, Deschamps JY, Libeau L, Mendes-Madeira A, Guihal C, François A, Guyon R, Provost N, Lemoine F, Papal S, El-Amraoui A, Colle MA, ... Moullier P, et al. Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 265-77. PMID 24091916 DOI: 10.1038/Mt.2013.232  0.383
2014 Denard J, Jenny C, Blouin V, Moullier P, Svinartchouk F. Different protein composition and functional properties of adeno-associated virus-6 vector manufactured from the culture medium and cell lysates Molecular Therapy - Methods and Clinical Development. 1. DOI: 10.1038/Mtm.2014.31  0.384
2014 Servais L, Guiner CL, Montus M, Cherel Y, Francois V, Thibaud JL, Wary C, Matot B, Larche T, Guigand L, Dutilleul M, Goubin H, Deschamps JY, Domenger C, Allais M, ... ... Moullier P, et al. G.P.92 Neuromuscular Disorders. 24: 822. DOI: 10.1016/J.Nmd.2014.06.106  0.384
2014 Mack DL, Goddard M, Snyder JM, Doering J, Lawlor MW, Moullier P, O’Callaghan M, Beggs AH, Mavilio F, Poulard K, Latournerie V, Buj-Bello A, Childers M. G.P.41 Neuromuscular Disorders. 24: 807. DOI: 10.1016/J.Nmd.2014.06.055  0.389
2013 Perez IC, Le Guiner C, Ni W, Lyles J, Moullier P, Snyder RO. PCR-based detection of gene transfer vectors: application to gene doping surveillance. Analytical and Bioanalytical Chemistry. 405: 9641-53. PMID 23912835 DOI: 10.1007/S00216-013-7264-8  0.377
2013 Bucher T, Colle MA, Wakeling E, Dubreil L, Fyfe J, Briot-Nivard D, Maquigneau M, Raoul S, Cherel Y, Astord S, Duque S, Marais T, Voit T, Moullier P, Barkats M, et al. scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease. Human Gene Therapy. 24: 670-82. PMID 23799774 DOI: 10.1089/Hum.2012.218  0.325
2013 Guiner CL, Montus M, Servais L, Cherel Y, Hogrel JY, Carlier P, Masurier C, Adjali O, Mavilio F, Dickson G, Moullier P, Voit T. P.20.13 Gene therapy of Duchenne Muscular Dystrophy using rAAV vectors: Exon skipping and microdystrophin approaches in GRMD dogs Neuromuscular Disorders. 23: 842-843. DOI: 10.1016/J.Nmd.2013.06.703  0.439
2013 Cherel Y, Guiner CL, Guigand L, Dutilleul M, Larcher T, Goubin H, Fraysse B, Deschamps JY, Montus M, Servais L, Voit T, Moullier P. P.20.12 Gene therapy of Duchenne Muscular Dystrophy using rAAV vectors: Patterns of dystrophin expression and histological improvements Neuromuscular Disorders. 23: 842. DOI: 10.1016/J.Nmd.2013.06.702  0.398
2013 Childers M, Joubert R, Poulard K, Holder M, Grange R, Doering J, Lawlor M, Moal C, Jamet T, Danièle N, Martin C, Rivière C, Poppante K, Soker T, Hammer C, ... ... Moullier P, et al. P.4.3 Intravenous infusion of AAV8–MTM1 prolongs life and ameliorates severe muscle pathology in mouse and dog models of X-linked myotubular myopathy Neuromuscular Disorders. 23: 760. DOI: 10.1016/J.Nmd.2013.06.441  0.412
2013 Joubert R, Moal C, Vignaud A, Martin S, Richard I, Moullier P, Beggs AH, Childers MK, Mavilio F, Buj-Bello A. O.6 Restricting MTM1 transgene expression to skeletal muscle in AAV-mediated gene therapy for myotubular myopathy Neuromuscular Disorders. 23: 741. DOI: 10.1016/J.Nmd.2013.06.384  0.423
2012 Petit L, Lhériteau E, Weber M, Le Meur G, Deschamps JY, Provost N, Mendes-Madeira A, Libeau L, Guihal C, Colle MA, Moullier P, Rolling F. Restoration of vision in the pde6β-deficient dog, a large animal model of rod-cone dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2019-30. PMID 22828504 DOI: 10.1038/Mt.2012.134  0.363
2012 Veron P, Leborgne C, Monteilhet V, Boutin S, Martin S, Moullier P, Masurier C. Humoral and cellular capsid-specific immune responses to adeno-associated virus type 1 in randomized healthy donors Journal of Immunology. 188: 6418-6424. PMID 22593612 DOI: 10.4049/Jimmunol.1200620  0.39
2012 Denard J, Beley C, Kotin R, Lai-Kuen R, Blot S, Leh H, Asokan A, Samulski RJ, Moullier P, Voit T, Garcia L, Svinartchouk F. Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6. Journal of Virology. 86: 6620-31. PMID 22496229 DOI: 10.1128/Jvi.00297-12  0.381
2012 Nowrouzi A, Penaud-Budloo M, Kaeppel C, Appelt U, Guiner CL, Moullier P, Kalle Cv, Snyder RO, Schmidt M. Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver Molecular Therapy. 20: 1177-1186. PMID 22453768 DOI: 10.1038/Mt.2012.47  0.385
2012 Moullier P, Snyder RO. Recombinant adeno-associated viral vector reference standards Methods in Enzymology. 507: 297-311. PMID 22365780 DOI: 10.1016/B978-0-12-386509-0.00015-6  0.431
2012 Beggs A, Jamet T, Joubert R, Furth M, Holder M, Grange R, Lawlor M, Viola M, Poulard K, Masurier C, Martin S, Rivière C, Poppante K, Soker T, Hammer C, ... ... Moullier P, et al. T.O.4 Development of AAV-gene and protein-based therapies for X-linked myotubular myopathy Neuromuscular Disorders. 22: 907. DOI: 10.1016/J.Nmd.2012.06.341  0.4
2012 Thibaud JL, Wary C, Moullec S, Azzabou N, Guiner CL, Garcia L, Montus M, Cherel Y, Fromes Y, Servais L, Roques S, Moullier P, Voit T, Carlier PG. T.P.23 Quantitative evaluation of locoregional high venous pressure rAAV8-U7- ESE6-ESE8 exon-skipping therapy in the GRMD dog using NMR 1H imaging and 31P spectroscopy Neuromuscular Disorders. 22: 859. DOI: 10.1016/J.Nmd.2012.06.188  0.318
2012 Hordeaux J, Moreau S, Dubreil L, Deniaud J, Iacobelli F, Joussemet B, Guiner CL, Moullier P, Chérel Y, Colle M-. Efficient Central Nervous System Transduction by Intracisternal AAV10 Gene Transfer in Rats Journal of Comparative Pathology. 146: 52. DOI: 10.1016/J.Jcpa.2011.11.029  0.336
2011 Joussemet B, Belbellaa B, Mendes-Madeira A, Bucher T, Briot-Nivard D, Dubreil L, Colle MA, Cherel Y, Moullier P, Rolling F. Neonatal systemic delivery of scAAV9 in rodents and large animals results in gene transfer to RPE cells in the retina. Experimental Eye Research. 93: 491-502. PMID 21723863 DOI: 10.1016/J.Exer.2011.06.012  0.415
2011 Léger A, Le Guiner C, Nickerson ML, McGee Im K, Ferry N, Moullier P, Snyder RO, Penaud-Budloo M. Adeno-associated viral vector-mediated transgene expression is independent of DNA methylation in primate liver and skeletal muscle. Plos One. 6: e20881. PMID 21687632 DOI: 10.1371/Journal.Pone.0020881  0.399
2011 Monteilhet V, Saheb S, Boutin S, Leborgne C, Veron P, Montus MF, Moullier P, Benveniste O, Masurier C. A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8 Molecular Therapy. 19: 2084-2091. PMID 21629225 DOI: 10.1038/Mt.2011.108  0.421
2011 Ni W, Guiner CL, Gernoux G, Penaud-Budloo M, Moullier P, Snyder RO. Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates: implications for gene doping Gene Therapy. 18: 709-718. PMID 21390073 DOI: 10.1038/Gt.2011.19  0.404
2011 Ellinwood NM, Ausseil J, Desmaris N, Bigou S, Liu S, Jens JK, Snella EM, Mohammed EE, Thomson CB, Raoul S, Joussemet B, Roux F, Chérel Y, Lajat Y, Piraud M, ... ... Moullier P, et al. Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 251-9. PMID 21139569 DOI: 10.1038/Mt.2010.265  0.753
2010 Lhériteau E, Libeau L, Mendes-Madeira A, Deschamps JY, Weber M, Le Meur G, Provost N, Guihal C, Moullier P, Rolling F. Regulation of retinal function but nonrescue of vision in RPE65-deficient dogs treated with doxycycline-regulatable AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1085-93. PMID 20354505 DOI: 10.1038/Mt.2010.46  0.41
2010 Toromanoff A, Adjali O, Larcher T, Hill M, Guigand L, Chenuaud P, Deschamps JY, Gauthier O, Blancho G, Vanhove B, Rolling F, Chérel Y, Moullier P, Anegon I, Le Guiner C. Lack of immunotoxicity after regional intravenous (RI) delivery of rAAV to nonhuman primate skeletal muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 151-60. PMID 19888197 DOI: 10.1038/Mt.2009.251  0.421
2010 Colle MA, Piguet F, Bertrand L, Raoul S, Bieche I, Dubreil L, Sloothaak D, Bouquet C, Moullier P, Aubourg P, Cherel Y, Cartier N, Sevin C. Efficient intracerebral delivery of AAV5 vector encoding human ARSA in non-human primate. Human Molecular Genetics. 19: 147-58. PMID 19837699 DOI: 10.1093/Hmg/Ddp475  0.433
2009 Van Vliet K, Mohiuddin Y, McClung S, Blouin V, Rolling F, Moullier P, Agbandje-McKenna M, Snyder RO. Adeno-associated virus capsid serotype identification: Analytical methods development and application. Journal of Virological Methods. 159: 167-77. PMID 19447508 DOI: 10.1016/J.Jviromet.2009.03.020  0.334
2009 Stieger K, Belbellaa B, Le Guiner C, Moullier P, Rolling F. In vivo gene regulation using tetracycline-regulatable systems. Advanced Drug Delivery Reviews. 61: 527-41. PMID 19394373 DOI: 10.1016/J.Addr.2008.12.016  0.43
2009 Duque S, Joussemet B, Riviere C, Marais T, Dubreil L, Douar AM, Fyfe J, Moullier P, Colle MA, Barkats M. Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1187-96. PMID 19367261 DOI: 10.1038/Mt.2009.71  0.362
2009 Stieger K, Lhériteau E, Lhéariteau E, Moullier P, Rolling F. AAV-mediated gene therapy for retinal disorders in large animal models. Ilar Journal. 50: 206-24. PMID 19293463 DOI: 10.1093/Ilar.50.2.206  0.411
2009 Ciron C, Cressant A, Roux F, Raoul S, Cherel Y, Hantraye P, Déglon N, Schwartz B, Barkats M, Heard JM, Tardieu M, Moullier P, Colle MA. Human alpha-iduronidase gene transfer mediated by adeno-associated virus types 1, 2, and 5 in the brain of nonhuman primates: vector diffusion and biodistribution. Human Gene Therapy. 20: 350-60. PMID 19272011 DOI: 10.1089/Hum.2008.155  0.614
2009 Lhériteau E, Libeau L, Stieger K, Deschamps JY, Mendes-Madeira A, Provost N, Lemoine F, Mellersh C, Ellinwood NM, Cherel Y, Moullier P, Rolling F. The RPGRIP1-deficient dog, a promising canine model for gene therapy. Molecular Vision. 15: 349-61. PMID 19223988  0.666
2009 Stieger K, Schroeder J, Provost N, Mendes-Madeira A, Belbellaa B, Le Meur G, Weber M, Deschamps JY, Lorenz B, Moullier P, Rolling F. Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 516-23. PMID 19107120 DOI: 10.1038/Mt.2008.283  0.425
2009 Moreau A, Vicente R, Dubreil L, Adjali O, Podevin G, Jacquet C, Deschamps JY, Klatzmann D, Cherel Y, Taylor N, Moullier P, Zimmermann VS. Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 472-9. PMID 19088703 DOI: 10.1038/Mt.2008.272  0.455
2009 Ciron C, Cressant A, Roux F, Raoul S, Cherel Y, Hantraye P, Deglon N, Schwartz B, Barkats M, Heard JM, Tardieu M, Moullier P, Colle M. AAV1-, AAV2- and AAV5-Mediated human α-Iduronidase Gene Transfer In The Brain of Nonhuman Primate: Vector Diffusion and Bio Distribution Human Gene Therapy. 90106063907063. DOI: 10.1089/Hgt.2008.155  0.359
2008 Toromanoff A, Chérel Y, Guilbaud M, Penaud-Budloo M, Snyder RO, Haskins ME, Deschamps JY, Guigand L, Podevin G, Arruda VR, High KA, Stedman HH, Rolling F, Anegon I, Moullier P, et al. Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1291-1299. PMID 28178483 DOI: 10.1038/Mt.2008.87  0.674
2008 Moullier P, Snyder RO. International efforts for recombinant adeno-associated viral vector reference standards. Molecular Therapy. 16: 1185-1188. PMID 18574495 DOI: 10.1038/Mt.2008.125  0.374
2008 Penaud-Budloo M, Le Guiner C, Nowrouzi A, Toromanoff A, Chérel Y, Chenuaud P, Schmidt M, von Kalle C, Rolling F, Moullier P, Snyder RO. Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle. Journal of Virology. 82: 7875-85. PMID 18524821 DOI: 10.1128/Jvi.00649-08  0.407
2008 Toromanoff A, Chérel Y, Guilbaud M, Penaud-Budloo M, Snyder RO, Haskins ME, Deschamps JY, Guigand L, Podevin G, Arruda VR, High KA, Stedman HH, Rolling F, Anegon I, Moullier P, et al. Safety and efficacy of regional intravenous (r.i.) versus intramuscular (i.m.) delivery of rAAV1 and rAAV8 to nonhuman primate skeletal muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1291-9. PMID 18461055 DOI: 10.1038/mt.2008.87  0.629
2008 Stieger K, Colle MA, Dubreil L, Mendes-Madeira A, Weber M, Le Meur G, Deschamps JY, Provost N, Nivard D, Cherel Y, Moullier P, Rolling F. Subretinal delivery of recombinant AAV serotype 8 vector in dogs results in gene transfer to neurons in the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 916-23. PMID 18388922 DOI: 10.1038/Mt.2008.41  0.435
2008 Guilbaud M, Chadeuf G, Avolio F, François A, Moullier P, Recchia A, Salvetti A. Relative Influence of the Adeno-Associated Virus (AAV) Type 2 p5 Element for Recombinant AAV Vector Site-Specific Integration Journal of Virology. 82: 2590-2593. PMID 18094174 DOI: 10.1128/Jvi.01956-07  0.376
2007 Le Guiner C, Stieger K, Snyder RO, Rolling F, Moullier P. Immune responses to gene product of inducible promoters. Current Gene Therapy. 7: 334-46. PMID 17979680 DOI: 10.2174/156652307782151461  0.365
2006 Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Therapy. 14: 292-303. PMID 17024105 DOI: 10.1038/Sj.Gt.3302861  0.415
2006 Ciron C, Desmaris N, Colle MA, Raoul S, Joussemet B, Vérot L, Ausseil J, Froissart R, Roux F, Chérel Y, Ferry N, Lajat Y, Schwartz B, Vanier MT, Maire I, ... ... Moullier P, et al. Gene therapy of the brain in the dog model of Hurler's syndrome. Annals of Neurology. 60: 204-13. PMID 16718701 DOI: 10.1002/Ana.20870  0.637
2006 Stieger K, Le Meur G, Lasne F, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Martin L, Moullier P, Rolling F. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 967-75. PMID 16442848 DOI: 10.1016/J.Ymthe.2005.12.001  0.421
2006 Toromanoff A, Hill M, Cherel Y, Deschamps J, Gauthier O, Vanhove B, Rolling F, Moullier P, Anegon I, Guiner CL. 974. Constitutive Expression of a Mutated Form of CTLA4Ig after Gene Transfer Is Well Tolerated and Prevents Immune Responses Against an Immunogenic Transgene in Nonhuman Primates Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1067  0.38
2006 Toromanoff A, Cherel Y, Deschamps J, Arruda VR, High KA, Stedman HH, Haskins ME, Rolling F, Anegon I, Moullier P, Le Guiner C. 39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle Molecular Therapy. 13: S16-S17. DOI: 10.1016/J.Ymthe.2006.08.052  0.378
2005 François A, Guilbaud M, Awedikian R, Chadeuf G, Moullier P, Salvetti A. The Cellular TATA Binding Protein Is Required for Rep-Dependent Replication of a Minimal Adeno-Associated Virus Type 2 p5 Element Journal of Virology. 79: 11082-11094. PMID 16103159 DOI: 10.1128/Jvi.79.17.11082-11094.2005  0.329
2005 Chadeuf G, Ciron C, Moullier P, Salvetti A. Evidence for encapsidation of prokaryotic sequences during recombinant adeno-associated virus production and their in vivo persistence after vector delivery. Molecular Therapy. 12: 744-753. PMID 16023415 DOI: 10.1016/J.Ymthe.2005.06.003  0.433
2005 Fraefel C, Mendes-Madeira A, Mabon O, Lefebvre A, Meur GL, Ackermann M, Moullier P, Rolling F. In vivo gene transfer to the rat retina using herpes simplex virus type 1 (HSV-1)-based amplicon vectors. Gene Therapy. 12: 1283-1288. PMID 15889134 DOI: 10.1038/Sj.Gt.3302553  0.39
2005 Awedikian R, François A, Guilbaud M, Moullier P, Salvetti A. Intracellular route and biological activity of exogenously delivered Rep proteins from the adeno-associated virus type 2. Virology. 335: 252-263. PMID 15840524 DOI: 10.1016/J.Virol.2005.02.024  0.354
2005 Le Meur G, Weber M, Péréon Y, Mendes-Madeira A, Nivard D, Deschamps JY, Moullier P, Rolling F. Postsurgical assessment and long-term safety of recombinant adeno-associated virus-mediated gene transfer into the retinas of dogs and primates. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 500-6. PMID 15824224 DOI: 10.1001/Archopht.123.4.500  0.384
2005 Grez M, Galun E, Moullier P. The twelfth annual meeting of the European Society of Gene Therapy. Molecular Therapy. 11: 178-179. PMID 15717416 DOI: 10.1016/J.Ymthe.2004.12.013  0.349
2005 Provost N, Le Meur G, Weber M, Mendes-Madeira A, Podevin G, Cherel Y, Colle MA, Deschamps JY, Moullier P, Rolling F. Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 275-83. PMID 15668139 DOI: 10.1016/J.Ymthe.2004.09.022  0.385
2005 Moullier P. Editorial [Hot Topic: Recombinant Adeno-Associated Virus: Current Achievements and Limitations (Guest Editor: Philippe Moullier)] Current Gene Therapy. 5: 263-263. DOI: 10.2174/1566523054065002  0.311
2004 Geoffroy M, Epstein AL, Toublanc E, Moullier P, Salvetti A. Herpes Simplex Virus Type 1 ICP0 Protein Mediates Activation of Adeno-Associated Virus Type 2 rep Gene Expression from a Latent Integrated Form Journal of Virology. 78: 10977-10986. PMID 15452218 DOI: 10.1128/Jvi.78.20.10977-10986.2004  0.386
2004 Serhan F, Penaud M, Petit C, Leste-Lasserre T, Trajcevski S, Klatzmann D, Duisit G, Sonigo P, Moullier P. Early Detection of a Two-Long-Terminal-Repeat Junction Molecule in the Cytoplasm of Recombinant Murine Leukemia Virus-Infected Cells Journal of Virology. 78: 6190-6199. PMID 15163712 DOI: 10.1128/Jvi.78.12.6190-6199.2004  0.324
2004 Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, Cartier N, Epstein AL, Moullier P, Salvetti A. Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines Journal of Gene Medicine. 6: 555-564. PMID 15133766 DOI: 10.1002/Jgm.542  0.373
2004 Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Joussemet B, Bujard H, Samulski RJ, Favre D, Moullier P. Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 410-8. PMID 15006608 DOI: 10.1016/J.Ymthe.2003.12.015  0.432
2004 Blouin V, Brument N, Toublanc E, Raimbaud I, Moullier P, Salvetti A. Improving rAAV production and purification: Towards the definition of a scaleable process Journal of Gene Medicine. 6. PMID 14978765 DOI: 10.1002/Jgm.505  0.361
2004 Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Cherel Y, Casadevall N, Samulski RJ, Moullier P. Autoimmune anemia in macaques following erythropoietin gene therapy. Blood. 103: 3303-4. PMID 14739218 DOI: 10.1182/Blood-2003-11-3845  0.445
2004 Podevin G, Otta E, Nguyen JM, Pichard V, Aubert D, Moullier P, Ferry N. Factors influencing immune response after in vivo retrovirus-mediated gene transfer to the liver. The Journal of Gene Medicine. 6: 16-21. PMID 14716673 DOI: 10.1002/Jgm.469  0.37
2004 Chenuaud P, Larcher T, Rabinowitz J, Provost N, Cherel Y, Casadevall N, Samulski J, Moullier P. 1050. Autoimmune Anemia in Macaques Following Erythropoietin Gene Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.995  0.444
2003 Folliot S, Briot D, Conrath H, Provost N, Cherel Y, Moullier P, Rolling F. Sustained tetracycline-regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno-associated viral vector. The Journal of Gene Medicine. 5: 493-501. PMID 12797114 DOI: 10.1002/Jgm.367  0.421
2003 Weber M, Rabinowitz J, Provost N, Conrath H, Folliot S, Briot D, Chérel Y, Chenuaud P, Samulski J, Moullier P, Rolling F. Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 774-81. PMID 12788651 DOI: 10.1016/S1525-0016(03)00098-4  0.441
2003 Aubert D, Pichard V, Durand S, Moullier P, Ferry N. Cytotoxic immune response after retroviral-mediated hepatic gene transfer in rat does not preclude expression from adeno-associated virus 1 transduced muscles. Human Gene Therapy. 14: 473-81. PMID 12691612 DOI: 10.1089/104303403321467234  0.391
2003 Nony P, Chadeuf G, Tessier J, Moullier P, Salvetti A. Evidence for Packaging of rep-cap Sequences into Adeno-Associated Virus (AAV) Type 2 Capsids in the Absence of Inverted Terminal Repeats: a Model for Generation of rep-Positive AAV Particles Journal of Virology. 77: 776-781. PMID 12477885 DOI: 10.1128/Jvi.77.1.776-781.2003  0.356
2002 Brument N, Morenweiser R, Blouin V, Toublanc E, Raimbaud I, Chérel Y, Folliot S, Gaden F, Boulanger P, Kroner-Lux G, Moullier P, Rolling F, Salvetti A. A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and -5. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 678-86. PMID 12436964 DOI: 10.1006/Mthe.2002.0719  0.348
2002 Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marmé F, Chérel Y, Salvetti A, Hurtrel B, Heard JM, Rivière Y, Moullier P. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus. Journal of Virology. 76: 11605-11. PMID 12388721 DOI: 10.1128/Jvi.76.22.11605-11611.2002  0.62
2002 Duisit G, Conrath H, Saleun S, Folliot S, Provost N, Cosset FL, Sandrin V, Moullier P, Rolling F. Five recombinant simian immunodeficiency virus pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 446-54. PMID 12377185 DOI: 10.1006/Mthe.2002.0690  0.351
2002 Serhan F, Jourdan N, Saleun S, Moullier P, Duisit G. Characterization of Producer Cell-Dependent Restriction of Murine Leukemia Virus Replication Journal of Virology. 76: 6609-6617. PMID 12050374 DOI: 10.1128/Jvi.76.13.6609-6617.2002  0.324
2002 Aubert D, Ménoret S, Chiari E, Pichard V, Durand S, Tesson L, Moullier P, Anegon I, Ferry N. Cytotoxic immune response blunts long-term transgene expression after efficient retroviral-mediated hepatic gene transfer in rat. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 388-96. PMID 11945065 DOI: 10.1006/Mthe.2002.0561  0.38
2002 Nègre D, Duisit G, Mangeot P-, Moullier P, Darlix J-, Cosset F-. Lentiviral Vectors Derived from Simian Immunodeficiency Virus Current Topics in Microbiology and Immunology. 261: 53-74. PMID 11892253 DOI: 10.1007/978-3-642-56114-6_3  0.367
2001 Verdugo ME, Scarpino V, Moullier P, Haskins ME, Aguirre GD, Ray J. Adenoviral vector-mediated beta-glucuronidase cDNA transfer to treat MPS VII RPE in vitro. Current Eye Research. 23: 357-67. PMID 11910525 DOI: 10.1076/Ceyr.23.5.357.5444  0.357
2001 Favre D, Provost N, Blouin V, Blancho G, Chérel Y, Salvetti A, Moullier P. Immediate and long-term safety on recombinant adeno-associated virus injection into the nonhuman primate muscle Molecular Therapy. 4: 559-566. PMID 11735340 DOI: 10.1006/Mthe.2001.0494  0.406
2001 Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, Linden RM, Moullier P, Salvetti A. Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences. Journal of Virology. 75: 9991-4. PMID 11559833 DOI: 10.1128/Jvi.75.20.9991-9994.2001  0.337
2001 Serguera C, Sarkis C, Ridet J, Colin P, Moullier P, Mallet J. Primary Adult Human Astrocytes as an ex Vivo Vehicle for β-Glucuronidase Delivery in the Brain Molecular Therapy. 3: 875-881. PMID 11407901 DOI: 10.1006/Mthe.2001.0319  0.31
2001 Agard C, Ligeza C, Dupas B, Izembart A, Kouri CE, Moullier P, Ferry N. Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Therapy. 8: 128-136. PMID 11263528 DOI: 10.1038/Sj.Cgt.7700281  0.365
2001 Tessier J, Chadeuf G, Nony P, Avet-Loiseau H, Moullier P, Salvetti A. Characterization of Adenovirus-Induced Inverted Terminal Repeat-Independent Amplification of Integrated Adeno-Associated Virus rep-cap Sequences Journal of Virology. 75: 375-383. PMID 11119606 DOI: 10.1128/Jvi.75.1.375-383.2001  0.391
2000 Nègre D, Mangeot PE, Duisit G, Blanchard S, Vidalain PO, Leissner P, Winter AJ, Rabourdin-Combe C, Mehtali M, Moullier P, Darlix JL, Cosset FL. Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells Gene Therapy. 7: 1613-1623. PMID 11083469 DOI: 10.1038/Sj.Gt.3301292  0.449
2000 Favre D, Cherel Y, Provost N, Blouin V, Ferry N, Moullier P, Salvetti A. Hyaluronidase enhances recombinant adeno-associated virus (rAAV)-mediated gene transfer in the rat skeletal muscle Gene Therapy. 7: 1417-1420. PMID 10981669 DOI: 10.1038/Sj.Gt.3301256  0.406
2000 Chadeuf G, Favre D, Tessier J, Provost N, Nony P, Kleinschmidt J, Moullier P, Salvetti A. Efficient recombinant adeno-associated virus production by a stable rep-cap HeLa cell line correlates with adenovirus-induced amplification of the integrated rep-cap genome. The Journal of Gene Medicine. 2: 260-8. PMID 10953917 DOI: 10.1002/1521-2254(200007/08)2:4<260::Aid-Jgm111>3.0.Co;2-8  0.402
1999 Duisit G, Saleun S, Douthe S, Barsoum J, Chadeuf G, Moullier P. Baculovirus vector requires electrostatic interactions including heparan sulfate for efficient gene transfer in mammalian cells. Journal of Gene Medicine. 1: 93-102. PMID 10738573 DOI: 10.1002/(Sici)1521-2254(199903/04)1:2<93::Aid-Jgm19>3.0.Co;2-1  0.36
1999 Izembart A, Aguado E, Gauthier O, Aubert D, Moullier P, Ferry N. In vivo retrovirus-mediated gene transfer to the liver of dogs results in transient expression and induction of a cytotoxic immune response. Human Gene Therapy. 10: 2917-2925. PMID 10609653 DOI: 10.1089/10430349950016339  0.387
1999 Duisit G, Salvetti A, Moullier P, Cosset F. Functional characterization of adenoviral/retroviral chimeric vectors and their use for efficient screening of retroviral producer cell lines. Human Gene Therapy. 10: 189-200. PMID 10022544 DOI: 10.1089/10430349950018986  0.361
1999 Mauff BL, Boeffard F, Tesson L, Chadeuf G, Douthe S, Salvetti A, Moullier P, Soulillou JP, Anegon I. Analysis Of Gene Transfer Efficacy In Rat Islets With Adeno Virus, Adeno-Associated Virus And Baculovirus. Transplantation. 67. DOI: 10.1097/00007890-199904150-00256  0.368
1998 Salvetti A, Orève S, Chadeuf G, Favre D, Cherel Y, Champion-Arnaud P, David-Ameline J, Moullier P. Factors Influencing Recombinant Adeno-Associated Virus Production Human Gene Therapy. 9: 695-706. PMID 9551617 DOI: 10.1089/Hum.1998.9.5-695  0.367
1998 Bohl D, Salvetti A, Moullier P, Heard JM. Control of erythropoietin delivery by doxycycline in mice after intramuscular injection of adeno-associated vector Blood. 92: 1512-1517. DOI: 10.1182/Blood.V92.5.1512.417K43_1512_1517  0.468
1997 Moullier P, Salvetti A, Champion-Arnaud P, Ronco PM. Gene transfer into the kidney: current status and limitations. Nephron. 77: 139-151. PMID 9346379 DOI: 10.1159/000190265  0.395
1996 Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. [Gene therapy of lysosomal diseases]. Archives De PéDiatrie : Organe Officiel De La SociéTe FrançAise De PéDiatrie. 3: 65s-68s. PMID 8795971 DOI: 10.1016/0929-693X(96)85996-3  0.679
1995 Naffakh N, Moullier P, Salvetti A, Bohl D, Danos O, Heard JM. Delivery of therapeutic proteins from genetically-modified cells. Restorative Neurology and Neuroscience. 8: 67-9. PMID 21551810 DOI: 10.3233/Rnn-1995-81216  0.658
1995 Salvetti A, Moullier P, Cornet V, Brooks D, Hopwood JJ, Danos O, Heard JM. In vivo delivery of human alpha-L-iduronidase in mice implanted with neo-organs. Human Gene Therapy. 6: 1153-9. PMID 8527473 DOI: 10.1089/Hum.1995.6.9-1153  0.691
1995 Cartier N, Lopez J, Moullier P, Rocchiccioli F, Rolland MO, Jorge P, Mosser J, Mandel JL, Bougnères PF, Danos O, Aubourg P. Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 92: 1674-1678. PMID 7878038 DOI: 10.1073/Pnas.92.5.1674  0.573
1995 Moullier P, Bohl D, Cardoso J, Heard JM, Danos O. Long-term delivery of a lysosomal enzyme by genetically modified fibroblasts in dogs. Nature Medicine. 1: 353-7. PMID 7585066 DOI: 10.1038/Nm0495-353  0.684
1994 Moullier P, Friedlander G, Calise D, Ronco P, Perricaudet M, Ferry N. Adenoviral-mediated gene transfer to renal tubular cells in vivo. Kidney International. 45: 1220-1225. PMID 8007594 DOI: 10.1038/Ki.1994.162  0.362
1993 Moullier P, Maréchal V, Danos O, Heard JM. Continuous systemic secretion of a lysosomal enzyme by genetically modified mouse skin fibroblasts. Transplantation. 56: 427-32. PMID 8356601 DOI: 10.1097/00007890-199308000-00034  0.683
1993 Moullier P, Bohl D, Heard JM, Danos O. Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts. Nature Genetics. 4: 154-9. PMID 8348154 DOI: 10.1038/Ng0693-154  0.67
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