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Thomas J Stout, PhD - Publications

Affiliations: 
1986-1992 Chemistry Cornell University, Ithaca, NY, United States 
 1992-1997 University of California, San Francisco, San Francisco, CA 
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 Brinen LS, Stout TJ. Can mosquitoes be bitten? A new hope for anti-malarial drug design. Structure (London, England : 1993). 11: 1309-10. PMID 14604516 DOI: 10.1016/J.Str.2003.10.011  0.563
1999 Costi PM, Rinaldi M, Tondi D, Pecorari P, Barlocco D, Ghelli S, Stroud RM, Santi DV, Stout TJ, Musiu C, Marangiu EM, Pani A, Congiu D, Loi GA, La Colla P. Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibition. Journal of Medicinal Chemistry. 42: 2112-24. PMID 10377217 DOI: 10.1021/jm9900016  0.42
1999 Stout TJ, Tondi D, Rinaldi M, Barlocco D, Pecorari P, Santi DV, Kuntz ID, Stroud RM, Shoichet BK, Costi MP. Structure-based design of inhibitors specific for bacterial thymidylate synthase. Biochemistry. 38: 1607-17. PMID 9931028 DOI: 10.1021/Bi9815896  0.465
1998 Stout TJ, Schellenberger U, Santi DV, Stroud RM. Crystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilis. Biochemistry. 37: 14736-47. PMID 9778348 DOI: 10.1021/Bi981270L  0.435
1998 Sage CR, Michelitsch MD, Stout TJ, Biermann D, Nissen R, Finer-Moore J, Stroud RM. D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry. 37: 13893-901. PMID 9753479 DOI: 10.2210/Pdb1Bjg/Pdb  0.404
1998 Stout TJ, Sage CR, Stroud RM. The additivity of substrate fragments in enzyme-ligand binding. Structure (London, England : 1993). 6: 839-48. PMID 9687366 DOI: 10.1016/S0969-2126(98)00086-0  0.375
1997 Sage CR, Rutenber EE, Stout TJ, Stroud RM. An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q. Biochemistry. 35: 16270-81. PMID 8973201 DOI: 10.1021/Bi961269R  0.428
1996 Stout TJ, Stroud RM. The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition. Structure (London, England : 1993). 4: 67-77. PMID 8805515 DOI: 10.1016/S0969-2126(96)00010-X  0.429
1996 Stout TJ, Costi MP, Barlocco D, Rinaldi M, Shoichet B, Perry KM, Kuntz ID, Stroud RM. Structure-based discovery of a new class of enzyme inhibitors Acta Crystallographica Section a Foundations of Crystallography. 52: C207-C207. DOI: 10.1107/S0108767396091064  0.448
1996 Sage CR, Rutenber EE, Stout TJ, Stroud RM. Short-circuiting a water-mediated enzyme reaction Acta Crystallographica Section a Foundations of Crystallography. 52: C239-C239. DOI: 10.1107/S0108767396089830  0.349
1995 Elbaum D, Porco JAJ, Stout TJ, Clardy J, Schreiber SL. Stereochemical and Conformational Effects on the Cycloaromatization of Dynemicin A-Related Molecules Journal of the American Chemical Society. 117: 211-225. DOI: 10.1021/Ja00106A025  0.449
1994 Trischman JA, Tapiolas DM, Jensen PR, Dwight R, Fenical W, McKee TC, Ireland CM, Stout TJ, Clardy J. Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete Journal of the American Chemical Society. 116: 757-758. DOI: 10.1021/Ja00081A042  0.376
1993 Zheng GQ, Chang CJ, Stout TJ, Clardy J, Ho DK, Cassady JM. Ohioensins: novel benzonaphthoxanthenones from Polytrichum ohioense The Journal of Organic Chemistry. 58: 366-372. DOI: 10.1021/Jo00054A019  0.435
1993 Shin J, Fenical W, Stout TJ, Clardy J. New cembradiene diterpenoids from an undescribed Caribbean gorgonian of the genus Eunicea Tetrahedron. 49: 515-524. DOI: 10.1016/S0040-4020(01)86256-6  0.471
1992 Hagihara M, Anthony NJ, Stout TJ, Clardy J, Schreiber SL. Vinylogous polypeptides: an alternative peptide backbone Journal of the American Chemical Society. 114: 6568-6570. DOI: 10.1021/Ja00042A052  0.348
1992 Kimura Y, Nishibe M, Nakajima H, Hamasaki T, Shigemitsu N, Sugawara F, Stout TJ, Clardy J. Emeniveol; A new pollen growth inhibitor from the fungus, Emericella nivea Tetrahedron Letters. 33: 6987-6990. DOI: 10.1016/S0040-4039(00)60913-9  0.458
1991 Chikashita H, Porco JA, Stout TJ, Clardy J, Schreiber SL. Synthesis of the angular anthraquinone subunit of dynemicin A The Journal of Organic Chemistry. 56: 1692-1694. DOI: 10.1021/Jo00005A008  0.388
1991 Sugawara F, Strobel S, Strobel G, Larsen RD, Berglund DL, Gray G, Takahashi N, Coval SJ, Stout TJ, Clardy J. The structure and biological activity of cercosporamide from Cercosporidium henningsii The Journal of Organic Chemistry. 56: 909-910. DOI: 10.1021/Jo00003A002  0.429
1991 Tapiolas DM, Roman M, Fenical W, Stout TJ, Clardy J. Octalactins A and B: cytotoxic eight-membered-ring lactones from a marine bacterium, Streptomyces sp Journal of the American Chemical Society. 113: 4682-4683. DOI: 10.1021/Ja00012A048  0.415
1991 Kigoshi H, Niwa H, Yamada K, Stout TJ, Clardy J. The three-dimensional structure of neohalicholactone, an unusual fatty acid metabolite from the marine sponge halichondria okadai kadota Tetrahedron Letters. 32: 2427-2428. DOI: 10.1016/S0040-4039(00)74344-9  0.426
1991 Stout TJ, Clardy J, Charles Pathirana I, Penical W. Aplasmomycin c: Structural studies of a marine antibiotic Tetrahedron. 47: 3511-3520. DOI: 10.1016/S0040-4020(01)80865-6  0.46
1990 Akee RK, Carroll TR, Yoshida WY, Scheuer PJ, Stout TJ, Clardy J. Two imidazole alkaloids from a sponge The Journal of Organic Chemistry. 55: 1944-1946. DOI: 10.1021/Jo00293A048  0.419
1990 Zabriskie TM, Foster MP, Stout TJ, Clardy J, Ireland CM. Studies on the solution- and solid-state structure of patellin 2 Journal of the American Chemical Society. 112: 8080-8084. DOI: 10.1021/Ja00178A035  0.45
1990 Porco JA, Schoenen FJ, Stout TJ, Clardy J, Schreiber SL. Transannular Diels-Alder route to systems related to dynemicin A Journal of the American Chemical Society. 112: 7410-7411. DOI: 10.1021/Ja00176A060  0.349
1990 Evans DA, Kaldor SW, Jones TK, Clardy J, Stout TJ. Total synthesis of the macrolide antibiotic cytovaricin Journal of the American Chemical Society. 112: 7001-7031. DOI: 10.1021/Ja00175A038  0.447
1989 Ayer WA, Craw PA, Stout TJ, Clardy J. Novel sesquiterpenoids from the fairy ring fungus, Marasmiusoreades Canadian Journal of Chemistry. 67: 773-778. DOI: 10.1139/V89-116  0.495
1989 Manker DC, Faulkner DJ, Stout TJ, Clardy J. The baconipyrones. Novel polypropionates from the pulmonate Siphonaria baconi The Journal of Organic Chemistry. 54: 5371-5374. DOI: 10.1021/Jo00283A036  0.414
1989 Zheng GQ, Chang CJ, Stout TJ, Clardy J, Cassady JM. Ohioensin-A: a novel benzonaphthoxanthenone from Polytrichum ohioense Journal of the American Chemical Society. 111: 5500-5501. DOI: 10.1021/Ja00196A085  0.415
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