Kenneth Walsh - Publications

Affiliations: 
Boston University School of Medicine, Boston, MA 
Area:
cardiovascular cell growth, differentiation and apoptosis
Website:
https://www.bumc.bu.edu/busm/profile/kenneth-walsh/

233 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gladyshev VN, Kritchevsky SB, Clarke SG, Cuervo AM, Fiehn O, de Magalhães JP, Mau T, Maes M, Moritz R, Niedernhofer LJ, Van Schaftingen E, Tranah GJ, Walsh K, Yura Y, Zhang B, et al. Molecular Damage in Aging. Nature Aging. 1: 1096-1106. PMID 36846190 DOI: 10.1038/s43587-021-00150-3  0.417
2018 Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. Journal of the American Heart Association. 7. PMID 29887522 DOI: 10.1161/Jaha.117.008441  0.716
2018 Fuster JJ, Zuriaga MA, Polackal M, Walsh K. Abstract 018: TET2 Loss of Function-driven Clonal Hematopoiesis Promotes Age-related Vascular and Systemic Inflammation and Metabolic Dysfunction in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.018  0.314
2017 Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Scientific Reports. 7: 17326. PMID 29229927 DOI: 10.1038/S41598-017-17509-5  0.316
2017 Neppl RL, Wu CL, Walsh K. lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy. The Journal of Cell Biology. PMID 28855249 DOI: 10.1083/Jcb.201612100  0.308
2017 Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Frontiers in Cardiovascular Medicine. 4: 27. PMID 28529941 DOI: 10.3389/Fcvm.2017.00027  0.315
2017 Karki S, Ngo D, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A Regulates Adipose Tissue Angiogenesis via Anti-Angiogenic VEGFA165b in Obese Humans. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00776.2016. PMID 28411232 DOI: 10.1152/Ajpheart.00776.2016  0.347
2017 Wu CL, Satomi Y, Walsh K. RNA-seq and metabolomic analyses of Akt1-mediated muscle growth reveals regulation of regenerative pathways and changes in the muscle secretome. Bmc Genomics. 18: 181. PMID 28209124 DOI: 10.1186/S12864-017-3548-2  0.324
2017 Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, ... ... Walsh K, et al. Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (New York, N.Y.). PMID 28104796 DOI: 10.1126/Science.Aag1381  0.315
2016 Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vascular Medicine (London, England). PMID 27688298 DOI: 10.1177/1358863X16666693  0.346
2016 Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. Embo Molecular Medicine. PMID 27234440 DOI: 10.15252/Emmm.201506151  0.76
2016 Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. Plos One. 11: e0151515. PMID 26999812 DOI: 10.1371/Journal.Pone.0151515  0.307
2016 Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26800561 DOI: 10.1161/Atvbaha.115.306578  0.328
2015 Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal of the American Heart Association. 5. PMID 26722122 DOI: 10.1161/Jaha.115.002277  0.371
2015 Shimizu I, Walsh K. The Whitening of Brown Fat and Its Implications for Weight Management in Obesity. Current Obesity Reports. 4: 224-9. PMID 26627217 DOI: 10.1007/S13679-015-0157-8  0.332
2015 Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R. C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury. The Journal of Biological Chemistry. PMID 26487714 DOI: 10.1074/Jbc.M115.690784  0.326
2015 Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, ... ... Walsh K, et al. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. PMID 26375005 DOI: 10.1038/Nature15372  0.367
2015 Shah D, Romero F, Duong M, Wang N, Paudyal B, Suratt BT, Kallen CB, Sun J, Zhu Y, Walsh K, Summer R. Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury. Scientific Reports. 5: 11362. PMID 26068229 DOI: 10.1038/Srep11362  0.324
2015 Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N. C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism. Molecular and Cellular Biology. 35: 2173-85. PMID 25870106 DOI: 10.1128/Mcb.01518-14  0.395
2015 Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 64: 1235-48. PMID 25352637 DOI: 10.2337/Db14-1164  0.343
2015 Dorn GW, Song M, Walsh K. Functional implications of mitofusin 2-mediated mitochondrial-SR tethering. Journal of Molecular and Cellular Cardiology. 78: 123-8. PMID 25252175 DOI: 10.1016/J.Yjmcc.2014.09.015  0.31
2015 Cheng KK, Akasaki Y, Lecommandeur E, Lindsay RT, Murfitt S, Walsh K, Griffin JL. Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation. Journal of Proteome Research. 14: 342-52. PMID 25231380 DOI: 10.1021/Pr500756U  0.349
2015 Hayakawa S, Ohashi K, Shibata R, Kataoka Y, Miyabe M, Enomoto T, Joki Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Ogawa H, Matsuo K, Hiramatsu-Ito M, van den Hoff MJ, ... Walsh K, et al. Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model. Journal of the American Society of Nephrology : Jasn. 26: 636-46. PMID 25071081 DOI: 10.1681/Asn.2014020210  0.37
2014 Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, ... Walsh K, et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nature Medicine. 20: 1464-71. PMID 25362254 DOI: 10.1038/Nm.3703  0.349
2014 Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, et al. Cardiovascular risks associated with low dose ionizing particle radiation. Plos One. 9: e110269. PMID 25337914 DOI: 10.1371/Journal.Pone.0110269  0.301
2014 Zeng L, Maruyama S, Nakamura K, Parker-Duffen JL, Adham IM, Zhong X, Lee HK, Querfurth H, Walsh K. The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis. Skeletal Muscle. 4: 16. PMID 25161767 DOI: 10.1186/2044-5040-4-16  0.533
2014 Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N. Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity. Circulation. 130: 1072-80. PMID 25116954 DOI: 10.1161/Circulationaha.113.008171  0.322
2014 Hanatani S, Izumiya Y, Araki S, Rokutanda T, Kimura Y, Walsh K, Ogawa H. Akt1-mediated fast/glycolytic skeletal muscle growth attenuates renal damage in experimental kidney disease. Journal of the American Society of Nephrology : Jasn. 25: 2800-11. PMID 25012168 DOI: 10.1681/Asn.2013091025  0.319
2014 Miyabe M, Ohashi K, Shibata R, Uemura Y, Ogura Y, Yuasa D, Kambara T, Kataoka Y, Yamamoto T, Matsuo K, Joki Y, Enomoto T, Hayakawa S, Hiramatsu-Ito M, Ito M, ... ... Walsh K, et al. Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury. Cardiovascular Research. 103: 111-20. PMID 24743592 DOI: 10.1093/Cvr/Cvu105  0.341
2014 Parker-Duffen JL, Nakamura K, Silver M, Zuriaga MA, MacLauchlan S, Aprahamian TR, Walsh K. Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. The Journal of Biological Chemistry. 289: 16200-13. PMID 24742672 DOI: 10.1074/Jbc.M114.548115  0.34
2014 Shimizu I, Aprahamian T, Kikuchi R, Shimizu A, Papanicolaou KN, MacLauchlan S, Maruyama S, Walsh K. Vascular rarefaction mediates whitening of brown fat in obesity. The Journal of Clinical Investigation. 124: 2099-112. PMID 24713652 DOI: 10.1172/Jci71643  0.731
2014 Kwon B, Kumar P, Lee HK, Zeng L, Walsh K, Fu Q, Barakat A, Querfurth HW. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Human Molecular Genetics. 23: 3681-94. PMID 24556217 DOI: 10.1093/Hmg/Ddu077  0.541
2014 Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. The Journal of Biological Chemistry. 289: 8633-44. PMID 24482236 DOI: 10.1074/Jbc.M113.517219  0.403
2014 Parker-Duffen JL, Walsh K. Cardiometabolic effects of adiponectin. Best Practice & Research. Clinical Endocrinology & Metabolism. 28: 81-91. PMID 24417948 DOI: 10.1016/J.Beem.2013.09.001  0.336
2014 Nakamura K, Fuster JJ, Walsh K. Adipokines: a link between obesity and cardiovascular disease. Journal of Cardiology. 63: 250-9. PMID 24355497 DOI: 10.1016/J.Jjcc.2013.11.006  0.307
2013 Parker-Duffen JL, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel MS, Ranscht B, Walsh K. T-cadherin is essential for adiponectin-mediated revascularization. The Journal of Biological Chemistry. 288: 24886-97. PMID 23824191 DOI: 10.1074/Jbc.M113.454835  0.341
2013 Yoshida S, Aihara K, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama K, Akaike M, Matsumoto M, ... ... Walsh K, et al. Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling. Circulation. 128: 60-71. PMID 23723256 DOI: 10.1161/Circulationaha.113.001533  0.309
2013 Shimizu I, Walsh K. Vascular remodeling mediated by Angptl2 produced from perivascular adipose tissue. Journal of Molecular and Cellular Cardiology. 59: 176-8. PMID 23528806 DOI: 10.1016/J.Yjmcc.2013.03.009  0.304
2013 Li Y, Wong K, Walsh K, Gao B, Zang M. Retinoic acid receptor β stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice Journal of Biological Chemistry. 288: 10490-10504. PMID 23430257 DOI: 10.1074/Jbc.M112.429852  0.305
2013 Zhu Y, Pereira RO, O'Neill BT, Riehle C, Ilkun O, Wende AR, Rawlings TA, Zhang YC, Zhang Q, Klip A, Shiojima I, Walsh K, Abel ED. Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation. Molecular Endocrinology (Baltimore, Md.). 27: 172-84. PMID 23204326 DOI: 10.1210/Me.2012-1210  0.337
2013 Fetalvero KM, Yu Y, Goetschkes M, Liang G, Valdez RA, Gould T, Triantafellow E, Bergling S, Loureiro J, Eash J, Lin V, Porter JA, Finan PM, Walsh K, Yang Y, et al. Defective autophagy and mTORC1 signaling in myotubularin null mice. Molecular and Cellular Biology. 33: 98-110. PMID 23109424 DOI: 10.1128/Mcb.01075-12  0.353
2012 Shimano M, Ouchi N, Walsh K. Cardiokines: recent progress in elucidating the cardiac secretome. Circulation. 126: e327-32. PMID 23169257 DOI: 10.1161/Circulationaha.112.150656  0.401
2012 Shiojima I, Schiekofer S, Schneider JG, Belisle K, Sato K, Andrassy M, Galasso G, Walsh K. Short-term akt activation in cardiac muscle cells improves contractile function in failing hearts. The American Journal of Pathology. 181: 1969-76. PMID 23031259 DOI: 10.1016/J.Ajpath.2012.08.020  0.427
2012 Ogura Y, Ouchi N, Ohashi K, Shibata R, Kataoka Y, Kambara T, Kito T, Maruyama S, Yuasa D, Matsuo K, Enomoto T, Uemura Y, Miyabe M, Ishii M, Yamamoto T, ... ... Walsh K, et al. Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Circulation. 126: 1728-38. PMID 22929303 DOI: 10.1161/Circulationaha.112.115089  0.329
2012 Panse KD, Felkin LE, López-Olañeta MM, Gómez-Salinero J, Villalba M, Muñoz L, Nakamura K, Shimano M, Walsh K, Barton PJ, Rosenthal N, Lara-Pezzi E. Follistatin-like 3 mediates paracrine fibroblast activation by cardiomyocytes. Journal of Cardiovascular Translational Research. 5: 814-26. PMID 22915069 DOI: 10.1007/s12265-012-9400-9  0.303
2012 Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K. Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circulation Research. 111: 1012-26. PMID 22904094 DOI: 10.1161/Circresaha.112.274142  0.74
2012 Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, ... ... Walsh K, et al. Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell. 149: 1298-313. PMID 22682250 DOI: 10.1016/J.Cell.2012.03.047  0.308
2012 Ouchi N, Walsh K. Cardiovascular and metabolic regulation by the adiponectin/C1q/tumor necrosis factor-related protein family of proteins. Circulation. 125: 3066-8. PMID 22653085 DOI: 10.1161/Circulationaha.112.114181  0.322
2012 Papanicolaou KN, Phillippo MM, Walsh K. Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion. American Journal of Physiology. Heart and Circulatory Physiology. 303: H243-55. PMID 22636681 DOI: 10.1152/Ajpheart.00185.2012  0.713
2012 Lee HK, Rocnik E, Fu Q, Kwon B, Zeng L, Walsh K, Querfurth H. Foxo/atrogin induction in human and experimental myositis. Neurobiology of Disease. 46: 463-75. PMID 22590725 DOI: 10.1016/J.Nbd.2012.02.011  0.551
2012 Ngoh GA, Papanicolaou KN, Walsh K. Loss of mitofusin 2 promotes endoplasmic reticulum stress. The Journal of Biological Chemistry. 287: 20321-32. PMID 22511781 DOI: 10.1074/Jbc.M112.359174  0.728
2012 Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. Journal of Immunology (Baltimore, Md. : 1950). 188: 854-63. PMID 22156343 DOI: 10.4049/Jimmunol.1100426  0.329
2012 Araki S, Izumiya Y, Hanatani S, Rokutanda T, Usuku H, Akasaki Y, Takeo T, Nakagata N, Walsh K, Ogawa H. Akt1-mediated skeletal muscle growth attenuates cardiac dysfunction and remodeling after experimental myocardial infarction. Circulation. Heart Failure. 5: 116-25. PMID 22135402 DOI: 10.1161/Circheartfailure.111.964783  0.401
2012 Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. American Journal of Physiology. Heart and Circulatory Physiology. 302: H167-79. PMID 22037195 DOI: 10.1152/Ajpheart.00833.2011  0.738
2011 Summer R, Walsh K, Medoff BD. Obesity and pulmonary arterial hypertension: Is adiponectin the molecular link between these conditions? Pulmonary Circulation. 1: 440-7. PMID 22530098 DOI: 10.4103/2045-8932.93542  0.331
2011 Shimano M, Ouchi N, Nakamura K, van Wijk B, Ohashi K, Asaumi Y, Higuchi A, Pimentel DR, Sam F, Murohara T, van den Hoff MJ, Walsh K. Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 108: E899-906. PMID 21987816 DOI: 10.1073/Pnas.1108559108  0.417
2011 Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y, Walsh K, Murohara T, Ouchi N. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. The Journal of Biological Chemistry. 286: 34552-8. PMID 21849507 DOI: 10.1074/Jbc.M111.277319  0.334
2011 Lugus JJ, Ngoh GA, Bachschmid MM, Walsh K. Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells. Journal of Molecular and Cellular Cardiology. 51: 885-93. PMID 21839087 DOI: 10.1016/J.Yjmcc.2011.07.023  0.366
2011 El-Armouche A, Ouchi N, Tanaka K, Doros G, Wittköpper K, Schulze T, Eschenhagen T, Walsh K, Sam F. Follistatin-like 1 in chronic systolic heart failure: a marker of left ventricular remodeling. Circulation. Heart Failure. 4: 621-7. PMID 21622850 DOI: 10.1161/Circheartfailure.110.960625  0.347
2011 Jadhav R, Dodd T, Smith E, Bailey E, Delucia AL, Russell JC, Madison R, Potter B, Walsh K, Jo H, Rocic P. Angiotensin type I receptor blockade in conjunction with enhanced Akt activation restores coronary collateral growth in the metabolic syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1938-49. PMID 21335466 DOI: 10.1152/Ajpheart.00282.2010  0.306
2011 Papanicolaou KN, Khairallah RJ, Ngoh GA, Chikando A, Luptak I, O'Shea KM, Riley DD, Lugus JJ, Colucci WS, Lederer WJ, Stanley WC, Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Molecular and Cellular Biology. 31: 1309-28. PMID 21245373 DOI: 10.1128/Mcb.00911-10  0.74
2011 Shimano M, Ouchi N, Nakamura K, Oshima Y, Higuchi A, Pimentel DR, Panse KD, Lara-Pezzi E, Lee SJ, Sam F, Walsh K. Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy. The Journal of Biological Chemistry. 286: 9840-8. PMID 21245136 DOI: 10.1074/Jbc.M110.197079  0.399
2011 Kim MH, Kay DI, Rudra RT, Chen BM, Hsu N, Izumiya Y, Martinez L, Spencer MJ, Walsh K, Grinnell AD, Crosbie RH. Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice. Human Molecular Genetics. 20: 1324-38. PMID 21245083 DOI: 10.1093/Hmg/Ddr015  0.344
2011 Ikeda H, Shiojima I, Oka T, Yoshida M, Maemura K, Walsh K, Igarashi T, Komuro I. Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice. Molecular and Cellular Biology. 31: 1054-65. PMID 21189286 DOI: 10.1128/Mcb.00732-10  0.325
2010 Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M. Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure. European Journal of Heart Failure. 12: 1290-6. PMID 21098579 DOI: 10.1093/Eurjhf/Hfq102  0.372
2010 O'Shea KM, Chess DJ, Khairallah RJ, Hecker PA, Lei B, Walsh K, Des Rosiers C, Stanley WC. ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin. Lipids in Health and Disease. 9: 95. PMID 20819225 DOI: 10.1186/1476-511X-9-95  0.333
2010 Zeng L, Akasaki Y, Sato K, Ouchi N, Izumiya Y, Walsh K. Insulin-like 6 is induced by muscle injury and functions as a regenerative factor. The Journal of Biological Chemistry. 285: 36060-9. PMID 20807758 DOI: 10.1074/Jbc.M110.160879  0.562
2010 Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A, Walsh K. Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science (New York, N.Y.). 329: 454-7. PMID 20558665 DOI: 10.1126/Science.1188280  0.333
2010 Ikeda Y, Aihara K, Akaike M, Sato T, Ishikawa K, Ise T, Yagi S, Iwase T, Ueda Y, Yoshida S, Azuma H, Walsh K, Tamaki T, Kato S, Matsumoto T. Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice. Molecular Endocrinology (Baltimore, Md.). 24: 1338-48. PMID 20501642 DOI: 10.1210/Me.2009-0402  0.369
2010 Ohashi K, Ouchi N, Higuchi A, Shaw RJ, Walsh K. LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. The Journal of Biological Chemistry. 285: 22291-8. PMID 20489196 DOI: 10.1074/Jbc.M110.123794  0.393
2010 Papanicolaou KN, Streicher JM, Ishikawa TO, Herschman H, Wang Y, Walsh K. Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. Journal of Molecular and Cellular Cardiology. 49: 196-209. PMID 20399788 DOI: 10.1016/J.Yjmcc.2010.04.002  0.758
2010 Biolo A, Shibata R, Ouchi N, Kihara S, Sonoda M, Walsh K, Sam F. Determinants of adiponectin levels in patients with chronic systolic heart failure. The American Journal of Cardiology. 105: 1147-52. PMID 20381668 DOI: 10.1016/J.Amjcard.2009.12.015  0.32
2010 O'Shea KM, Chess DJ, Khairallah RJ, Rastogi S, Hecker PA, Sabbah HN, Walsh K, Stanley WC. Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1639-45. PMID 20348222 DOI: 10.1152/Ajpheart.00957.2009  0.36
2010 Kondo K, Shibata R, Unno K, Shimano M, Ishii M, Kito T, Shintani S, Walsh K, Ouchi N, Murohara T. Impact of a single intracoronary administration of adiponectin on myocardial ischemia/reperfusion injury in a pig model. Circulation. Cardiovascular Interventions. 3: 166-73. PMID 20332381 DOI: 10.1016/J.Cardfail.2009.07.166  0.32
2010 Shimano M, Ouchi N, Shibata R, Ohashi K, Pimentel DR, Murohara T, Walsh K. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. Journal of Molecular and Cellular Cardiology. 49: 210-20. PMID 20206634 DOI: 10.1016/j.yjmcc.2010.02.021  0.307
2010 Ouchi N, Asaumi Y, Ohashi K, Higuchi A, Sono-Romanelli S, Oshima Y, Walsh K. DIP2A functions as a FSTL1 receptor. The Journal of Biological Chemistry. 285: 7127-34. PMID 20054002 DOI: 10.1074/Jbc.M109.069468  0.394
2010 Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. The Journal of Biological Chemistry. 285: 6153-60. PMID 20028977 DOI: 10.1074/Jbc.M109.088708  0.313
2010 Sam F, Duhaney TA, Sato K, Wilson RM, Ohashi K, Sono-Romanelli S, Higuchi A, De Silva DS, Qin F, Walsh K, Ouchi N. Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure. Endocrinology. 151: 322-31. PMID 19850745 DOI: 10.1210/En.2009-0806  0.365
2009 Sam F, Walsh K. What can adiponectin say about left ventricular function? Heart (British Cardiac Society). 96: 331-2. PMID 19934101 DOI: 10.1136/Hrt.2009.178590  0.341
2009 Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. The Journal of Biological Chemistry. 284: 35839-49. PMID 19828446 DOI: 10.1074/Jbc.M109.057273  0.411
2009 Oshima Y, Ouchi N, Shimano M, Pimentel DR, Papanicolaou KN, Panse KD, Tsuchida K, Lara-Pezzi E, Lee SJ, Walsh K. Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. Circulation. 120: 1606-15. PMID 19805648 DOI: 10.1161/Circulationaha.109.872200  0.749
2009 Ikeda H, Shiojima I, Ozasa Y, Yoshida M, Holzenberger M, Kahn CR, Walsh K, Igarashi T, Abel ED, Komuro I. Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 47: 664-75. PMID 19744489 DOI: 10.1016/J.Yjmcc.2009.08.028  0.353
2009 Ohashi K, Ouchi N, Sato K, Higuchi A, Ishikawa TO, Herschman HR, Kihara S, Walsh K. Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Molecular and Cellular Biology. 29: 3487-99. PMID 19398582 DOI: 10.1128/Mcb.00126-09  0.404
2009 Wang CY, Kim HH, Hiroi Y, Sawada N, Salomone S, Benjamin LE, Walsh K, Moskowitz MA, Liao JK. Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. Science Signaling. 2: ra11. PMID 19293429 DOI: 10.1126/Scisignal.2000143  0.356
2009 Balcazar N, Sathyamurthy A, Elghazi L, Gould A, Weiss A, Shiojima I, Walsh K, Bernal-Mizrachi E. mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability. The Journal of Biological Chemistry. 284: 7832-42. PMID 19144649 DOI: 10.1074/Jbc.M807458200  0.309
2009 Peter AK, Ko CY, Kim MH, Hsu N, Ouchi N, Rhie S, Izumiya Y, Zeng L, Walsh K, Crosbie RH. Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy. Human Molecular Genetics. 18: 318-27. PMID 18986978 DOI: 10.1093/Hmg/Ddn358  0.544
2008 Qin W, Zhao W, Ho L, Wang J, Walsh K, Gandy S, Pasinetti GM. Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deterioration. Annals of the New York Academy of Sciences. 1147: 335-47. PMID 19076455 DOI: 10.1196/Annals.1427.024  0.321
2008 Izumiya Y, Bina HA, Ouchi N, Akasaki Y, Kharitonenkov A, Walsh K. FGF21 is an Akt-regulated myokine. Febs Letters. 582: 3805-10. PMID 18948104 DOI: 10.1016/J.Febslet.2008.10.021  0.358
2008 Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K. Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism. The Journal of Biological Chemistry. 283: 32802-11. PMID 18718903 DOI: 10.1074/Jbc.M803440200  0.392
2008 Ouchi N, Walsh K. A novel role for adiponectin in the regulation of inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1219-21. PMID 18565846 DOI: 10.1161/Atvbaha.108.165068  0.337
2008 Song Y, Coleman L, Shi J, Beppu H, Sato K, Walsh K, Loscalzo J, Zhang YY. Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H677-90. PMID 18552156 DOI: 10.1152/Ajpheart.91519.2007  0.322
2008 Shibata R, Numaguchi Y, Matsushita K, Sone T, Kubota R, Ohashi T, Ishii M, Kihara S, Walsh K, Ouchi N, Murohara T. Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction. The American Journal of Cardiology. 101: 1712-5. PMID 18549845 DOI: 10.1016/J.Amjcard.2008.02.057  0.316
2008 Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 117: 3099-108. PMID 18519848 DOI: 10.1161/Circulationaha.108.767673  0.405
2008 Schiekofer S, Belisle K, Galasso G, Schneider JG, Boehm BO, Burster T, Schmitz G, Walsh K. Angiogenic-regulatory network revealed by molecular profiling heart tissue following Akt1 induction in endothelial cells. Angiogenesis. 11: 289-99. PMID 18491207 DOI: 10.1007/S10456-008-9112-6  0.432
2008 Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, Lan F, Walsh K, Wierzbicki M, Verbeuren TJ, Cohen RA, Zang M. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. The Journal of Biological Chemistry. 283: 20015-26. PMID 18482975 DOI: 10.1074/Jbc.M802187200  0.333
2008 Shibata R, Skurk C, Ouchi N, Galasso G, Kondo K, Ohashi T, Shimano M, Kihara S, Murohara T, Walsh K. Adiponectin promotes endothelial progenitor cell number and function. Febs Letters. 582: 1607-12. PMID 18423403 DOI: 10.1016/J.Febslet.2008.04.006  0.349
2008 Mogi M, Walsh K, Iwai M, Horiuchi M. Akt-FOXO3a signaling affects human endothelial progenitor cell differentiation. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 31: 153-9. PMID 18360030 DOI: 10.1291/Hypres.31.153  0.316
2008 Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K. Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. Febs Letters. 582: 1147-50. PMID 18339320 DOI: 10.1016/J.Febslet.2008.03.002  0.401
2008 Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K. Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice. Cell Metabolism. 7: 159-72. PMID 18249175 DOI: 10.1016/J.Cmet.2007.11.003  0.531
2008 Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circulation Research. 102: 16-31. PMID 18174472 DOI: 10.1161/Circresaha.107.164186  0.735
2008 Lee HY, You HJ, Won JY, Youn SW, Cho HJ, Park KW, Park WY, Seo JS, Park YB, Walsh K, Oh BH, Kim HS. Forkhead factor, FOXO3a, induces apoptosis of endothelial cells through activation of matrix metalloproteinases Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 302-308. PMID 18063811 DOI: 10.1161/Atvbaha.107.150664  0.321
2007 Lee HY, Youn SW, Kim JY, Park KW, Hwang CI, Park WY, Oh BH, Park YB, Walsh K, Seo JS, Kim HS. FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 112-20. PMID 18032780 DOI: 10.1161/Atvbaha.107.153304  0.309
2007 Walsh K, Shiojima I. Cardiac growth and angiogenesis coordinated by intertissue interactions. The Journal of Clinical Investigation. 117: 3176-9. PMID 17975662 DOI: 10.1172/Jci34126  0.354
2007 Phung TL, Eyiah-Mensah G, O'Donnell RK, Bieniek R, Shechter S, Walsh K, Kuperwasser C, Benjamin LE. Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression. Cancer Research. 67: 5070-5. PMID 17545582 DOI: 10.1158/0008-5472.Can-06-3341  0.314
2007 Shibata R, Izumiya Y, Sato K, Papanicolaou K, Kihara S, Colucci WS, Sam F, Ouchi N, Walsh K. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. Journal of Molecular and Cellular Cardiology. 42: 1065-74. PMID 17499764 DOI: 10.1016/J.Yjmcc.2007.03.808  0.749
2007 Shibata R, Sato K, Kumada M, Izumiya Y, Sonoda M, Kihara S, Ouchi N, Walsh K. Adiponectin accumulates in myocardial tissue that has been damaged by ischemia-reperfusion injury via leakage from the vascular compartment Cardiovascular Research. 74: 471-479. PMID 17362898 DOI: 10.1016/J.Cardiores.2007.02.010  0.315
2007 Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clinica Chimica Acta; International Journal of Clinical Chemistry. 380: 24-30. PMID 17343838 DOI: 10.1016/J.Cca.2007.01.026  0.303
2007 Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K. Adiponectin modulates inflammatory reactions via calreticulin receptor–dependent clearance of early apoptotic bodies Journal of Clinical Investigation. 117: 375-386. PMID 17256056 DOI: 10.1172/Jci29709  0.344
2007 Lee HY, Chung JW, Youn SW, Kim JY, Park KW, Koo BK, Oh BH, Park YB, Chaqour B, Walsh K, Kim HS. Forkhead transcription factor FOXO3a is a negative regulator of angiogenic immediate early gene CYR61, leading to inhibition of vascular smooth muscle cell proliferation and neointimal hyperplasia. Circulation Research. 100: 372-80. PMID 17234971 DOI: 10.1161/01.Res.0000257945.97958.77  0.371
2007 Fisslthaler B, Fleming I, Keserü B, Walsh K, Busse R. Fluid shear stress and NO decrease the activity of the hydroxy-methylglutaryl coenzyme A reductase in endothelial cells via the AMP-activated protein kinase and FoxO1. Circulation Research. 100: e12-21. PMID 17218607 DOI: 10.1161/01.Res.0000257747.74358.1C  0.323
2007 Hopkins TA, Ouchi N, Shibata R, Walsh K. Adiponectin actions in the cardiovascular system. Cardiovascular Research. 74: 11-8. PMID 17140553 DOI: 10.1016/J.Cardiores.2006.10.009  0.383
2007 Ouchi N, Shibata R, Walsh K. Cardioprotective Actions of Adiponectin High Blood Pressure & Cardiovascular Prevention. 14: 69-73. DOI: 10.2165/00151642-200714020-00003  0.346
2006 Shiojima I, Walsh K. Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway. Genes & Development. 20: 3347-65. PMID 17182864 DOI: 10.1101/Gad.1492806  0.398
2006 Moussa CE, Fu Q, Kumar P, Shtifman A, Lopez JR, Allen PD, LaFerla F, Weinberg D, Magrane J, Aprahamian T, Walsh K, Rosen KM, Querfurth HW. Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2165-7. PMID 16940437 DOI: 10.1096/Fj.06-5763Fje  0.302
2006 Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, et al. Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Cancer Cell. 10: 159-170. PMID 16904613 DOI: 10.1016/J.Ccr.2006.07.003  0.321
2006 Schiekofer S, Shiojima I, Sato K, Galasso G, Oshima Y, Walsh K. Microarray analysis of Akt1 activation in transgenic mouse hearts reveals transcript expression profiles associated with compensatory hypertrophy and failure. Physiological Genomics. 27: 156-70. PMID 16882883 DOI: 10.1152/Physiolgenomics.00234.2005  0.405
2006 Ouchi N, Shibata R, Walsh K. Targeting adiponectin for cardioprotection. Expert Opinion On Therapeutic Targets. 10: 573-81. PMID 16848693 DOI: 10.1517/14728222.10.4.573  0.355
2006 Ouchi N, Shibata R, Walsh K. Cardioprotection by adiponectin. Trends in Cardiovascular Medicine. 16: 141-6. PMID 16781946 DOI: 10.1016/J.Tcm.2006.03.001  0.374
2006 Rocnik EF, Liu P, Sato K, Walsh K, Vaziri C. The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity. The Journal of Biological Chemistry. 281: 22855-64. PMID 16774925 DOI: 10.1074/Jbc.M513463200  0.353
2006 Walsh K. Akt signaling and growth of the heart. Circulation. 113: 2032-4. PMID 16651482 DOI: 10.1161/Circulationaha.106.615138  0.408
2006 Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 47: 887-93. PMID 16567591 DOI: 10.1161/01.Hyp.0000215207.54689.31  0.387
2006 Mukai Y, Rikitake Y, Shiojima I, Wolfrum S, Satoh M, Takeshita K, Hiroi Y, Salomone S, Kim HH, Benjamin LE, Walsh K, Liao JK. Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt. The Journal of Clinical Investigation. 116: 334-43. PMID 16453020 DOI: 10.1172/Jci26223  0.357
2005 Galasso G, Schiekofer S, Sato K, Shibata R, Handy DE, Ouchi N, Leopold JA, Loscalzo J, Walsh K. Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circulation Research. 98: 254-61. PMID 16373599 DOI: 10.1161/01.Res.0000200740.57764.52  0.361
2005 Magrané J, Rosen KM, Smith RC, Walsh K, Gouras GK, Querfurth HW. Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10960-9. PMID 16306409 DOI: 10.1523/Jneurosci.1723-05.2005  0.303
2005 Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nature Medicine. 11: 1096-103. PMID 16155579 DOI: 10.1038/Nm1295  0.369
2005 Partovian C, Zhuang Z, Moodie K, Lin M, Ouchi N, Sessa WC, Walsh K, Simons M. PKCalpha activates eNOS and increases arterial blood flow in vivo. Circulation Research. 97: 482-7. PMID 16081872 DOI: 10.1161/01.Res.0000179775.04114.45  0.348
2005 Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. The Journal of Clinical Investigation. 115: 2108-18. PMID 16075055 DOI: 10.1172/Jci24682  0.396
2005 Skaletz-Rorowski A, Kureishi Y, Shiojima I, Walsh K. The pro- and antiangiogenic effects of statins. Seminars in Vascular Medicine. 4: 395-400. PMID 15861320 DOI: 10.1055/S-2004-869596  0.371
2005 Ouchi N, Shibata R, Walsh K. AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle. Circulation Research. 96: 838-46. PMID 15790954 DOI: 10.1161/01.Res.0000163633.10240.3B  0.365
2005 Kim HS, Skurk C, Maatz H, Shiojima I, Ivashchenko Y, Yoon SW, Park YB, Walsh K. Akt/FOXO3a signaling modulates the endothelial stress response through regulation of heat shock protein 70 expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1042-4. PMID 15784720 DOI: 10.1096/Fj.04-2841Fje  0.364
2005 Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. The Journal of Biological Chemistry. 280: 20814-23. PMID 15781459 DOI: 10.1074/Jbc.M500528200  0.602
2005 Taniyama Y, Ito M, Sato K, Kuester C, Veit K, Tremp G, Liao R, Colucci WS, Ivashchenko Y, Walsh K, Shiojima I. Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy. Journal of Molecular and Cellular Cardiology. 38: 375-85. PMID 15698844 DOI: 10.1016/J.Yjmcc.2004.12.002  0.421
2005 Park KW, Kim DH, You HJ, Sir JJ, Jeon SI, Youn SW, Yang HM, Skurk C, Park YB, Walsh K, Kim HS. Activated forkhead transcription factor inhibits neointimal hyperplasia after angioplasty through induction of p27 Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 742-747. PMID 15662024 DOI: 10.1161/01.Atv.0000156288.70849.26  0.36
2005 Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE. Microvascular patterning is controlled by fine-tuning the Akt signal. Proceedings of the National Academy of Sciences of the United States of America. 102: 128-33. PMID 15611473 DOI: 10.1073/Pnas.0403198102  0.358
2005 Shiojima I, Walsh K. The role of vascular endothelial growth factor in restenosis: the controversy continues. Circulation. 110: 2283-6. PMID 15492329 DOI: 10.1161/01.Cir.0000146723.23523.47  0.331
2005 Jones SP, Greer JJ, Ware PD, Yang J, Walsh K, Lefer DJ. Deficiency of iNOS does not attenuate severe congestive heart failure in mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H365-70. PMID 15319210 DOI: 10.1152/Ajpheart.00245.2004  0.343
2004 Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart Nature Medicine. 10: 1384-1389. PMID 15558058 DOI: 10.1038/Nm1137  0.377
2004 Choi JH, Hurt J, Yoon CH, Kim JH, Lee CS, Youn SW, Oh IY, Skurk C, Murohara T, Park YB, Walsh K, Kim HS. Augmentation of therapeutic augiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3β activity Journal of Biological Chemistry. 279: 49430-49438. PMID 15339925 DOI: 10.1074/Jbc.M402088200  0.357
2004 Yang HM, Kim HS, Park KW, You HJ, Jeon SI, Youn SW, Kim SH, Oh BH, Lee MM, Park YB, Walsh K. Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signaling Circulation. 110: 301-308. PMID 15238462 DOI: 10.1161/01.Cir.0000135467.43430.16  0.348
2004 Yang J, Sato K, Aprahamian T, Brown NJ, Hutcheson J, Bialik A, Perlman H, Walsh K. Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1466-73. PMID 15178561 DOI: 10.1161/01.Atv.0000134402.94963.2F  0.325
2004 Shibata R, Ouchi N, Kihara S, Sato K, Funahashi T, Walsh K. Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. The Journal of Biological Chemistry. 279: 28670-4. PMID 15123726 DOI: 10.1074/Jbc.M402558200  0.376
2004 Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 117: 399-412. PMID 15109499 DOI: 10.1016/S0092-8674(04)00400-3  0.319
2004 Aprahamian T, Rifkin I, Bonegio R, Hugel B, Freyssinet JM, Sato K, Castellot JJ, Walsh K. Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease. The Journal of Experimental Medicine. 199: 1121-31. PMID 15096538 DOI: 10.1084/Jem.20031557  0.31
2004 Skurk C, Walsh K. Death receptor induced apoptosis: a new mechanism of homocysteine-mediated endothelial cell cytotoxicity. Hypertension (Dallas, Tex. : 1979). 43: 1168-70. PMID 15096473 DOI: 10.1161/01.Hyp.0000127811.48554.12  0.302
2004 Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circulation Research. 94: 884-91. PMID 14988230 DOI: 10.1161/01.Res.0000124394.01180.Be  0.388
2004 Kobayashi H, Ouchi N, Kihara S, Walsh K, Kumada M, Abe Y, Funahashi T, Matsuzawa Y. Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circulation Research. 94: e27-31. PMID 14752031 DOI: 10.1161/01.Res.0000119921.86460.37  0.346
2004 Torella D, Rota M, Nurzynska D, Musso E, Monsen A, Shiraishi I, Zias E, Walsh K, Rosenzweig A, Sussman MA, Urbanek K, Nadal-Ginard B, Kajstura J, Anversa P, Leri A. Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circulation Research. 94: 514-24. PMID 14726476 DOI: 10.1161/01.Res.0000117306.10142.50  0.381
2004 Abid MR, Guo S, Minami T, Spokes KC, Ueki K, Skurk C, Walsh K, Aird WC. Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 294-300. PMID 14656735 DOI: 10.1161/01.Atv.0000110502.10593.06  0.357
2004 Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, Funahashi T, Walsh K. Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells Journal of Biological Chemistry. 279: 1304-1309. PMID 14557259 DOI: 10.1074/Jbc.M310389200  0.342
2004 Gorski DH, Walsh K. Control of vascular cell differentiation by homeobox transcription factors. Trends in Cardiovascular Medicine. 13: 213-20. PMID 12922016 DOI: 10.1016/S1050-1738(03)00081-1  0.36
2004 Mogi M, Walsh K, Miki T. The Role of Akt-Forkhead Signaling in the Hematopoietic Stem-Progenitor Cell Differentiation: Expansion of Hematopoietic and Endothelial Progenitors from Akt-1 Null Marrows and Peripheral Blood Involving FKHRL1-Activation. Blood. 104: 1704-1704. DOI: 10.1182/Blood.V104.11.1704.1704  0.351
2004 Phung T, Sun JF, Felske T, Shiojima I, Dvorak A, Nagy J, Walsh K, Dvorak H, Benjamin L. AKT/PKB REGULATES MICROVASCULAR REMODELING AND HOMEOSTASIS Cardiovascular Pathology. 13: 8. DOI: 10.1016/J.Carpath.2004.03.018  0.342
2003 Kovacic S, Soltys CL, Barr AJ, Shiojima I, Walsh K, Dyck JR. Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. The Journal of Biological Chemistry. 278: 39422-7. PMID 12890675 DOI: 10.1074/Jbc.M305371200  0.373
2003 Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, Skurk C, Summer R, Fine A, Quesenberry PJ, Walsh K. Akt signaling regulates side population cell phenotype via Bcrp1 translocation. The Journal of Biological Chemistry. 278: 39068-75. PMID 12851395 DOI: 10.1074/Jbc.M306362200  0.314
2003 Park KW, Yang HM, Youn SW, Yang HJ, Chae IH, Oh BH, Lee MM, Park YB, Choi YS, Kim HS, Walsh K. Constitutively active glycogen synthase kinase-3beta gene transfer sustains apoptosis, inhibits proliferation of vascular smooth muscle cells, and reduces neointima formation after balloon injury in rats. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1364-9. PMID 12805073 DOI: 10.1161/01.Atv.0000081633.53390.B4  0.337
2003 Suhara T, Magrané J, Rosen K, Christensen R, Kim HS, Zheng B, McPhie DL, Walsh K, Querfurth H. Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism. Neurobiology of Aging. 24: 437-51. PMID 12600720 DOI: 10.1016/S0197-4580(02)00135-5  0.34
2003 Lake AC, Bialik A, Walsh K, Castellot JJ. CCN5 is a growth arrest-specific gene that regulates smooth muscle cell proliferation and motility. The American Journal of Pathology. 162: 219-31. PMID 12507905 DOI: 10.1016/S0002-9440(10)63813-8  0.37
2003 Skaletz-Rorowski A, Lutchman M, Kureishi Y, Lefer DJ, Faust JR, Walsh K. HMG-CoA reductase inhibitors promote cholesterol-dependent Akt/PKB translocation to membrane domains in endothelial cells. Cardiovascular Research. 57: 253-64. PMID 12504836 DOI: 10.1016/S0008-6363(02)00618-1  0.348
2003 Schönherr E, Levkau B, Schaefer L, Kresse H, Walsh K. Decorin affects endothelial cells by Akt-dependent and -independent pathways. Annals of the New York Academy of Sciences. 973: 149-52. PMID 12485853 DOI: 10.1111/J.1749-6632.2002.Tb04625.X  0.331
2003 Six I, Kureishi Y, Luo Z, Walsh K. Akt signaling mediates VEGF/VPF vascular permeability in vivo. Febs Letters. 532: 67-9. PMID 12459464 DOI: 10.1016/S0014-5793(02)03630-X  0.339
2003 Lee P, Sata M, Lefer DJ, Factor SM, Walsh K, Kitsis RN. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 284: H456-63. PMID 12414449 DOI: 10.1152/Ajpheart.00777.2002  0.399
2003 Shiojima I, Sato K, Colucci WS, Walsh K. Conditional activation of Akt in the heart provides mechanistic insights into progression from compensated cardiac hypertrophy to heart failure Journal of Cardiac Failure. 9: S3. DOI: 10.1016/S1071-9164(03)00155-6  0.406
2002 Taniyama Y, Walsh K. Elevated myocardial Akt signaling ameliorates doxorubicin-induced congestive heart failure and promotes heart growth. Journal of Molecular and Cellular Cardiology. 34: 1241-7. PMID 12392981 DOI: 10.1006/Jmcc.2002.2068  0.396
2002 Soltys CL, Buchholz L, Gandhi M, Clanachan AS, Walsh K, Dyck JR. Phosphorylation of cardiac protein kinase B is regulated by palmitate. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1056-64. PMID 12181135 DOI: 10.1152/Ajpheart.00275.2002  0.337
2002 Shiojima I, Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circulation Research. 90: 1243-50. PMID 12089061 DOI: 10.1161/01.Res.0000022200.71892.9F  0.365
2002 Takahashi A, Kureishi Y, Yang J, Luo Z, Guo K, Mukhopadhyay D, Ivashchenko Y, Branellec D, Walsh K. Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth. Molecular and Cellular Biology. 22: 4803-14. PMID 12052887 DOI: 10.1128/Mcb.22.13.4803-4814.2002  0.391
2002 Suzuki E, Nishimatsu H, Satonaka H, Walsh K, Goto A, Omata M, Fujita T, Nagai R, Hirata Y. Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes. Circulation Research. 90: 1004-11. PMID 12016267 DOI: 10.1161/01.Res.0000017629.70769.Cc  0.306
2002 Suhara T, Kim HS, Kirshenbaum LA, Walsh K. Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation. Molecular and Cellular Biology. 22: 680-91. PMID 11756562 DOI: 10.1128/Mcb.22.2.680-691.2002  0.343
2002 Fujio Y, Mitsuuchi Y, Testa JR, Walsh K. Activation of Akt2 Inhibits anoikis and apoptosis induced by myogenic differentiation. Cell Death and Differentiation. 8: 1207-12. PMID 11753568 DOI: 10.1038/Sj.Cdd.4400919  0.348
2002 Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K, Koh GY. Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 126-128. PMID 11729102 DOI: 10.1096/Fj.01-0556Fje  0.363
2001 Wills KN, Mano T, Avanzini JB, Nguyen T, Antelman D, Gregory RJ, Smith RC, Walsh K. Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle alpha-actin promoter suppresses smooth muscle cell proliferation and neointima formation. Gene Therapy. 8: 1847-54. PMID 11821938 DOI: 10.1038/Sj.Gt.3301603  0.331
2001 Go YM, Boo YC, Park H, Maland MC, Patel R, Pritchard KA, Fujio Y, Walsh K, Darley-Usmar V, Jo H. Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 91: 1574-81. PMID 11568138 DOI: 10.1152/Jappl.2001.91.4.1574  0.31
2001 Llevadot J, Murasawa S, Kureishi Y, Uchida S, Masuda H, Kawamoto A, Walsh K, Isner JM, Asahara T. HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells. The Journal of Clinical Investigation. 108: 399-405. PMID 11489933 DOI: 10.1172/Jci13131  0.321
2001 Nishimatsu H, Suzuki E, Nagata D, Moriyama N, Satonaka H, Walsh K, Sata M, Kangawa K, Matsuo H, Goto A, Kitamura T, Hirata Y. Adrenomedullin induces endothelium-dependent vasorelaxation via the phosphatidylinositol 3-kinase/Akt-dependent pathway in rat aorta. Circulation Research. 89: 63-70. PMID 11440979 DOI: 10.1161/Hh1301.092498  0.322
2001 Suhara T, Mano T, Oliveira BE, Walsh K. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP). Circulation Research. 89: 13-9. PMID 11440972 DOI: 10.1161/Hh1301.092506  0.374
2001 Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. Journal of Molecular and Cellular Cardiology. 33: 907-21. PMID 11343414 DOI: 10.1006/Jmcc.2001.1367  0.322
2001 Lu Y, Parkyn L, Otterbein LE, Kureishi Y, Walsh K, Ray A, Ray P. Activated Akt protects the lung from oxidant-induced injury and delays death of mice. The Journal of Experimental Medicine. 193: 545-49. PMID 11181705 DOI: 10.1084/Jem.193.4.545  0.316
2001 Negoro S, Oh H, Tone E, Kunisada K, Fujio Y, Walsh K, Kishimoto T, Yamauchi-Takihara K. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation. 103: 555-61. PMID 11157722 DOI: 10.1161/01.Cir.103.4.555  0.361
2001 Panka DJ, Mano T, Suhara T, Walsh K, Mier JW. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. The Journal of Biological Chemistry. 276: 6893-6. PMID 11145953 DOI: 10.1074/Jbc.C000569200  0.34
2001 Shiojima I, Yefremashvili M, Abel E, Walsh K. Insulin signaling regulates heart size in postnatal development Journal of Molecular and Cellular Cardiology. 33: A176. DOI: 10.1016/S0022-2828(01)90675-3  0.332
2001 Walsh K, Shiojima I, Abel E. Insulin signaling in the heart Journal of Molecular and Cellular Cardiology. 33: A149. DOI: 10.1016/S0022-2828(01)90574-7  0.321
2000 Miao W, Luo Z, Kitsis RN, Walsh K. Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo Journal of Molecular and Cellular Cardiology. 32: 2397-2402. PMID 11113015 DOI: 10.1006/Jmcc.2000.1283  0.325
2000 Hixon ML, Muro-Cacho C, Wagner MW, Obejero-Paz C, Millie E, Fujio Y, Kureishi Y, Hassold T, Walsh K, Gualberto A. Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization. The Journal of Clinical Investigation. 106: 1011-20. PMID 11032861 DOI: 10.1172/Jci8252  0.342
2000 Nagata D, Suzuki E, Nishimatsu H, Yoshizumi M, Mano T, Walsh K, Sata M, Kakoki M, Goto A, Omata M, Hirata Y. Cyclin A downregulation and p21(cip1) upregulation correlate with GATA-6-induced growth arrest in glomerular mesangial cells. Circulation Research. 87: 699-704. PMID 11029406 DOI: 10.1161/01.Res.87.8.699  0.326
2000 Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Lefer DJ, Sessa WC, Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nature Medicine. 6: 1004-10. PMID 10973320 DOI: 10.1038/79510  0.363
2000 Luo Z, Fujio Y, Kureishi Y, Rudic RD, Daumerie G, Fulton D, Sessa WC, Walsh K. Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. The Journal of Clinical Investigation. 106: 493-9. PMID 10953024 DOI: 10.1172/Jci9419  0.345
2000 Walsh K, Smith RC, Kim HS. Vascular cell apoptosis in remodeling, restenosis, and plaque rupture. Circulation Research. 87: 184-8. PMID 10926867 DOI: 10.1161/01.Res.87.3.184  0.347
2000 Sata M, Walsh K. Fas ligand-deficient mice display enhanced leukocyte infiltration and intima hyperplasia in flow-restricted vessels. Journal of Molecular and Cellular Cardiology. 32: 1395-400. PMID 10900166 DOI: 10.1006/Jmcc.2000.1176  0.335
2000 Funamoto M, Fujio Y, Kunisada K, Negoro S, Tone E, Osugi T, Hirota H, Izumi M, Yoshizaki K, Walsh K, Kishimoto T, Yamauchi-Takihara K. Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes. The Journal of Biological Chemistry. 275: 10561-6. PMID 10744750 DOI: 10.1074/Jbc.275.14.10561  0.397
2000 Perlman H, Sata M, Krasinski K, Dorai T, Buttyan R, Walsh K. Adenovirus-encoded hammerhead ribozyme to Bcl-2 inhibits neointimal hyperplasia and induces vascular smooth muscle cell apoptosis. Cardiovascular Research. 45: 570-8. PMID 10728378 DOI: 10.1016/S0008-6363(99)00346-6  0.354
2000 Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against lschemia-reperfusion injury in mouse heart Circulation. 101: 660-667. PMID 10673259 DOI: 10.1161/01.Cir.101.6.660  0.387
2000 Sata M, Suhara T, Walsh K. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 309-16. PMID 10669625 DOI: 10.1161/01.Atv.20.2.309  0.333
1999 Perlman H, Pagliari LJ, Georganas C, Mano T, Walsh K, Pope RM. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. The Journal of Experimental Medicine. 190: 1679-88. PMID 10587358 DOI: 10.1084/Jem.190.11.1679  0.313
1999 Witzenbichler B, Kureishi Y, Luo Z, Le Roux A, Branellec D, Walsh K. Regulation of smooth muscle cell migration and integrin expression by the Gax transcription factor. The Journal of Clinical Investigation. 104: 1469-80. PMID 10562309 DOI: 10.1172/Jci7251  0.348
1999 Perlman H, Luo Z, Krasinski K, Le Roux A, Mahfoudi A, Smith RC, Branellec D, Walsh K. Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis. Gene Therapy. 6: 758-63. PMID 10505098 DOI: 10.1038/Sj.Gt.3300893  0.323
1999 Sata M, Walsh K. Cyclosporine downregulates Fas ligand expression on vascular endothelial cells: implication for accelerated vasculopathy by immunosuppressive therapy. Biochemical and Biophysical Research Communications. 263: 430-2. PMID 10491310 DOI: 10.1006/Bbrc.1999.1392  0.303
1999 Broceño C, Walsh K, Pons G. A 1.3-kb upstream 5' region of the rat phosphoglycerate mutase m gene confers testis and skeletal muscle-specific expression in transgenic mice. Biochemical and Biophysical Research Communications. 263: 244-250. PMID 10486284 DOI: 10.1006/Bbrc.1999.1227  0.314
1999 Ushio-Fukai M, Alexander RW, Akers M, Yin Q, Fujio Y, Walsh K, Griendling KK. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. The Journal of Biological Chemistry. 274: 22699-704. PMID 10428852 DOI: 10.1074/Jbc.274.32.22699  0.317
1999 Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 399: 597-601. PMID 10376602 DOI: 10.1038/21218  0.325
1999 Fujio Y, Guo K, Mano T, Mitsuuchi Y, Testa JR, Walsh K. Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival. Molecular and Cellular Biology. 19: 5073-82. PMID 10373556 DOI: 10.1128/Mcb.19.7.5073  0.341
1999 Fujio Y, Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. The Journal of Biological Chemistry. 274: 16349-54. PMID 10347193 DOI: 10.1074/Jbc.274.23.16349  0.352
1999 Walsh K, Sata M. Is extravasation a Fas-regulated process? Molecular Medicine Today. 5: 61-7. PMID 10200946 DOI: 10.1016/S1357-4310(98)01415-4  0.342
1999 Walsh K, Sata M. Negative regulation of inflammation by Fas ligand expression on the vascular endothelium. Trends in Cardiovascular Medicine. 9: 34-41. PMID 10189965 DOI: 10.1016/S1050-1738(99)00006-7  0.32
1999 Mano T, Luo Z, Malendowicz SL, Evans T, Walsh K. Reversal of GATA-6 downregulation promotes smooth muscle differentiation and inhibits intimal hyperplasia in balloon-injured rat carotid artery. Circulation Research. 84: 647-54. PMID 10189352 DOI: 10.1161/01.Res.84.6.647  0.326
1999 Cheema ZF, Wade SB, Sata M, Walsh K, Sohrabji F, Miranda RC. Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1754-70. PMID 10024361 DOI: 10.1523/Jneurosci.19-05-01754.1999  0.308
1999 Sata M, Walsh K. Endothelial cell apoptosis induced by oxidized LDL is associated with the down-regulation of the cellular caspase inhibitor FLIP. The Journal of Biological Chemistry. 273: 33103-6. PMID 9837872 DOI: 10.1074/Jbc.273.50.33103  0.343
1998 Sata M, Walsh K. Oxidized LDL activates fas-mediated endothelial cell apoptosis. The Journal of Clinical Investigation. 102: 1682-9. PMID 9802882 DOI: 10.1172/Jci3531  0.356
1998 Luo Z, Shyu KG, Gualberto A, Walsh K. Calcineurin inhibitors and cardiac hypertrophy. Nature Medicine. 4: 1092-3. PMID 9771723 DOI: 10.1038/2578  0.315
1998 Perlman H, Sata M, Le Roux A, Sedlak TW, Branellec D, Walsh K. Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity. The Embo Journal. 17: 3576-86. PMID 9649428 DOI: 10.1093/Emboj/17.13.3576  0.35
1998 Guo K, Andrés V, Walsh K. Nitric oxide-induced downregulation of Cdk2 activity and cyclin A gene transcription in vascular smooth muscle cells. Circulation. 97: 2066-72. PMID 9610538 DOI: 10.1161/01.Cir.97.20.2066  0.334
1998 Perlman H, Suzuki E, Simonson M, Smith RC, Walsh K. GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest. The Journal of Biological Chemistry. 273: 13713-8. PMID 9593712 DOI: 10.1074/Jbc.273.22.13713  0.362
1998 Sata M, Walsh K. TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nature Medicine. 4: 415-20. PMID 9546786 DOI: 10.1038/Nm0498-415  0.347
1998 Baumgartner I, Pieczek A, Manor O, Blair R, Kearney M, Walsh K, Isner JM. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation. 97: 1114-23. PMID 9537336 DOI: 10.1161/01.Cir.97.12.1114  0.302
1998 Sata M, Perlman H, Muruve DA, Silver M, Ikebe M, Libermann TA, Oettgen P, Walsh K. Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response. Proceedings of the National Academy of Sciences of the United States of America. 95: 1213-7. PMID 9448311 DOI: 10.1073/Pnas.95.3.1213  0.311
1997 Walsh K. Coordinate regulation of cell cycle and apoptosis during myogenesis Progress in Cell Cycle Research. 3: 53-58. PMID 9552406 DOI: 10.1007/978-1-4615-5371-7_5  0.314
1997 Walsh K, Perlman H. Cell cycle exit upon myogenic differentiation. Current Opinion in Genetics & Development. 7: 597-602. PMID 9388774 DOI: 10.1016/S0959-437X(97)80005-6  0.321
1997 Smith RC, Wills KN, Antelman D, Perlman H, Truong LN, Krasinski K, Walsh K. Adenoviral constructs encoding phosphorylation-competent full-length and truncated forms of the human retinoblastoma protein inhibit myocyte proliferation and neointima formation. Circulation. 96: 1899-905. PMID 9323079 DOI: 10.1161/01.Cir.96.6.1899  0.34
1997 Smith RC, Branellec D, Gorski DH, Guo K, Perlman H, Dedieu JF, Pastore C, Mahfoudi A, Denèfle P, Isner JM, Walsh K. p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes & Development. 11: 1674-89. PMID 9224717 DOI: 10.1101/Gad.11.13.1674  0.357
1997 Skopicki HA, Lyons GE, Schatteman G, Smith RC, Andrés V, Schirm S, Isner J, Walsh K. Embryonic expression of the Gax homeodomain protein in cardiac, smooth, and skeletal muscle. Circulation Research. 80: 452-62. PMID 9118475 DOI: 10.1161/01.Res.80.4.452  0.349
1997 Wei GL, Krasinski K, Kearney M, Isner JM, Walsh K, Andres V. Temporally and Spatially Coordinated Expression of Cell Cycle Regulatory Factors After Angioplasty Circulation Research. 80: 418-426. DOI: 10.1161/01.Res.0000435858.35902.Ea  0.305
1996 Suzuki E, Evans T, Lowry J, Truong L, Bell DW, Testa JR, Walsh K. The human GATA-6 gene: Structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals Genomics. 38: 283-290. PMID 8975704 DOI: 10.1006/Geno.1996.0630  0.323
1996 Fisher SA, Walsh K, Forehand CJ. Characterization of cardiac gene cis-regulatory elements in the early stages of chicken heart morphogenesis Journal of Molecular and Cellular Cardiology. 28: 113-122. PMID 8745219 DOI: 10.1006/Jmcc.1996.0011  0.318
1996 Andrés V, Walsh K. Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. The Journal of Cell Biology. 132: 657-66. PMID 8647896 DOI: 10.1083/Jcb.132.4.657  0.311
1995 Weir L, Chen D, Pastore C, Isner JM, Walsh K. Expression of gax, a growth arrest homeobox gene, is rapidly down-regulated in the rat carotid artery during the proliferative response to balloon injury. The Journal of Biological Chemistry. 270: 5457-61. PMID 7890661 DOI: 10.1074/Jbc.270.10.5457  0.348
1995 Suzuki E, Guo K, Kolman M, Yu YT, Walsh K. Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation Molecular and Cellular Biology. 15: 3415-3423. PMID 7760838 DOI: 10.1128/Mcb.15.6.3415  0.334
1995 Andrés V, Fisher S, Wearsch P, Walsh K. Regulation of Gax homeobox gene transcription by a combination of positive factors including myocyte-specific enhancer factor 2. Molecular and Cellular Biology. 15: 4272-4281. PMID 7623821 DOI: 10.1128/Mcb.15.8.4272  0.304
1995 Gorski DH, Walsh K. Mitogen-responsive nuclear factors that mediate growth control signals in vascular myocytes Cardiovascular Research. 30: 585-592. DOI: 10.1016/S0008-6363(96)88508-7  0.305
1987 Walsh K, Schena M, Flint AJ, Koshland DE. Compensatory regulation in metabolic pathways--responses to increases and decreases in citrate synthase levels. Biochemical Society Symposium. 54: 183-95. PMID 3332995  0.366
1985 Walsh K, Koshland DE. Characterization of rate-controlling steps in vivo by use of an adjustable expression vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 3577-81. PMID 3889909  0.363
1985 Koshland DE, Walsh K, LaPorte DC. Sensitivity of metabolic fluxes to covalent control Current Topics in Cellular Regulation. 27: 13-22. PMID 3004815 DOI: 10.1016/B978-0-12-152827-0.50009-8  0.355
1985 Walsh K, Koshland DE. Branch point control by the phosphorylation state of isocitrate dehydrogenase. A quantitative examination of fluxes during a regulatory transition. The Journal of Biological Chemistry. 260: 8430-7. PMID 2861202  0.379
1984 LaPorte DC, Walsh K, Koshland DE. The branch point effect. Ultrasensitivity and subsensitivity to metabolic control Journal of Biological Chemistry. 259: 14068-14075. PMID 6389540  0.349
1984 Walsh K, Koshland DE. Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt. The Journal of Biological Chemistry. 259: 9646-54. PMID 6378912  0.322
Show low-probability matches.