Year |
Citation |
Score |
2009 |
Riffell JL, Zimmerman C, Khong A, McHardy LM, Roberge M. Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation. Cell Cycle (Georgetown, Tex.). 8: 3025-38. PMID 19713760 DOI: 10.4161/Cc.8.18.9623 |
0.598 |
|
2009 |
Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. Bmc Microbiology. 9: 9. PMID 19144191 DOI: 10.1186/1471-2180-9-9 |
0.561 |
|
2008 |
Sturgeon CM, Cinel B, Díaz-Marrero AR, McHardy LM, Ngo M, Andersen RJ, Roberge M. Abrogation of ionizing radiation-induced G2 checkpoint and inhibition of nuclear export by Cryptocarya pyrones. Cancer Chemotherapy and Pharmacology. 61: 407-13. PMID 17440726 DOI: 10.1007/S00280-007-0483-Y |
0.631 |
|
2005 |
McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M. Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8. PMID 15897241 DOI: 10.1158/1535-7163.Mct-04-0310 |
0.597 |
|
2004 |
Warabi K, McHardy LM, Matainaho L, Van Soest R, Roskelley CD, Roberge M, Andersen RJ. Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. Journal of Natural Products. 67: 1387-9. PMID 15332859 DOI: 10.1021/Np0340246 |
0.503 |
|
2004 |
Baetz K, McHardy L, Gable K, Tarling T, Rebérioux D, Bryan J, Andersen RJ, Dunn T, Hieter P, Roberge M. Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action. Proceedings of the National Academy of Sciences of the United States of America. 101: 4525-30. PMID 15070751 DOI: 10.1073/Pnas.0307122101 |
0.606 |
|
2004 |
McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD. The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Research. 64: 1468-74. PMID 14973060 DOI: 10.1158/0008-5472.Can-03-2733 |
0.571 |
|
2002 |
Williams DE, Craig KS, Patrick B, McHardy LM, van Soest R, Roberge M, Andersen RJ. Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. The Journal of Organic Chemistry. 67: 245-58. PMID 11777468 DOI: 10.1021/Jo016101C |
0.522 |
|
2001 |
Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M. Inhibition of tumor cell invasion and angiogenesis by motuporamines. Cancer Research. 61: 6788-94. PMID 11559552 |
0.378 |
|
2001 |
Britton R, De Silva ED, Bigg CM, McHardy LM, Roberge M, Andersen RJ. Synthetic transformations of eleutherobin reveal new features of its microtubule-stabilizing pharmacophore [20] Journal of the American Chemical Society. 123: 8632-8633. PMID 11525686 DOI: 10.1021/Ja016459Q |
0.499 |
|
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