Year |
Citation |
Score |
2023 |
Laurent H, Hughes MDG, Walko M, Brockwell DJ, Mahmoudi N, Youngs TGA, Headen TF, Dougan L. Visualization of Self-Assembly and Hydration of a β-Hairpin through Integrated Small and Wide-Angle Neutron Scattering. Biomacromolecules. PMID 37874935 DOI: 10.1021/acs.biomac.3c00583 |
0.601 |
|
2023 |
Hughes MDG, Cussons S, Hanson BS, Cook KR, Feller T, Mahmoudi N, Baker DL, Ariëns R, Head DA, Brockwell DJ, Dougan L. Building block aspect ratio controls assembly, architecture, and mechanics of synthetic and natural protein networks. Nature Communications. 14: 5593. PMID 37696784 DOI: 10.1038/s41467-023-40921-7 |
0.655 |
|
2023 |
Aufderhorst-Roberts A, Cussons S, Brockwell DJ, Dougan L. Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel. Soft Matter. 19: 3167-3178. PMID 37067782 DOI: 10.1039/d2sm01225a |
0.674 |
|
2023 |
Cook KR, Head D, Dougan L. Modelling network formation in folded protein hydrogels by cluster aggregation kinetics. Soft Matter. PMID 36988480 DOI: 10.1039/d3sm00111c |
0.383 |
|
2023 |
Brown CP, Hughes MDG, Mahmoudi N, Brockwell DJ, Coletta PL, Peyman S, Evans SD, Dougan L. Structural and mechanical properties of folded protein hydrogels with embedded microbubbles. Biomaterials Science. PMID 36815670 DOI: 10.1039/d2bm01918c |
0.695 |
|
2022 |
Hughes MDG, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Tuning Protein Hydrogel Mechanics through Modulation of Nanoscale Unfolding and Entanglement in Postgelation Relaxation. Acs Nano. PMID 35731007 DOI: 10.1021/acsnano.2c02369 |
0.735 |
|
2021 |
Hanson BS, Dougan L. Intermediate Structural Hierarchy in Biological Networks Modulates the Fractal Dimension and Force Distribution of Percolating Clusters. Biomacromolecules. PMID 34420304 DOI: 10.1021/acs.biomac.1c00751 |
0.323 |
|
2021 |
Hughes MDG, Hanson BS, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Control of Nanoscale Protein Unfolding Defines Network Architecture and Mechanics of Protein Hydrogels. Acs Nano. PMID 34214394 DOI: 10.1021/acsnano.1c00353 |
0.74 |
|
2020 |
Aufderhorst-Roberts A, Hughes M, Hare A, Head DA, Kapur N, Brockwell DJ, Dougan L. Reaction Rate Governs the Viscoelasticity and Nanostructure of Folded Protein Hydrogels. Biomacromolecules. PMID 32870660 DOI: 10.1021/Acs.Biomac.0C01044 |
0.664 |
|
2020 |
Hughes MDG, Cussons S, Mahmoudi N, Brockwell DJ, Dougan L. Single molecule protein stabilisation translates to macromolecular mechanics of a protein network. Soft Matter. PMID 32578583 DOI: 10.1039/C9Sm02484K |
0.765 |
|
2020 |
Laurent H, Soper AK, Dougan L. Trimethylamine N-oxide (TMAO) resists the compression of water structure by magnesium perchlorate: terrestrial kosmotrope vs. Martian chaotrope. Physical Chemistry Chemical Physics : Pccp. 22: 4924-4937. PMID 32091074 DOI: 10.1039/C9Cp06324B |
0.32 |
|
2020 |
Hanson BS, Brown CP, Laurent H, Hughes MDG, Dougan L. Hierarchical biomechanics: student engagement activities with a focus on biological physics Physics Education. 55: 25015. DOI: 10.1088/1361-6552/Ab687E |
0.388 |
|
2020 |
Hanson BS, Dougan L. Network Growth and Structural Characteristics of Globular Protein Hydrogels Macromolecules. 53: 7335-7345. DOI: 10.1021/Acs.Macromol.0C00890 |
0.505 |
|
2019 |
Hanson BS, Head D, Dougan L. The hierarchical emergence of worm-like chain behaviour from globular domain polymer chains. Soft Matter. PMID 31595281 DOI: 10.1039/C9Sm01656B |
0.315 |
|
2018 |
Lenton S, Rhys NH, Towey JJ, Soper AK, Dougan L. Temperature-Dependent Segregation in Alcohol-Water Binary Mixtures Is Driven by Water Clustering. The Journal of Physical Chemistry. B. 122: 7884-7894. PMID 30039970 DOI: 10.1021/Acs.Jpcb.8B03543 |
0.303 |
|
2018 |
Batchelor M, Wolny M, Kurzawa M, Dougan L, Knight PJ, Peckham M. Determining Stable Single Alpha Helical (SAH) Domain Properties by Circular Dichroism and Atomic Force Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1805: 185-211. PMID 29971719 DOI: 10.1007/978-1-4939-8556-2_10 |
0.388 |
|
2017 |
Lenton S, Rhys NH, Towey JJ, Soper AK, Dougan L. Highly compressed water structure observed in a perchlorate aqueous solution. Nature Communications. 8: 919. PMID 29030555 DOI: 10.1038/S41467-017-01039-9 |
0.312 |
|
2017 |
Wolny M, Batchelor M, Bartlett GJ, Baker EG, Kurzawa M, Knight PJ, Dougan L, Woolfson DN, Paci E, Peckham M. Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability. Scientific Reports. 7: 44341. PMID 28287151 DOI: 10.1038/Srep44341 |
0.362 |
|
2017 |
Wolny M, Batchelor M, Bartlett GJ, Baker EG, Kurzawa M, Knight PJ, Dougan L, Takagi Y, Woolfson DN, Paci E, Peckham M. Design and Characterization of Long and Stable de novo Single α-Helix Domains Biophysical Journal. 112: 189a. DOI: 10.1016/J.Bpj.2016.11.1050 |
0.388 |
|
2016 |
da Silva MA, Lenton S, Hughes M, Brockwell DJ, Dougan L. Assessing the potential of folded globular polyproteins as hydrogel building blocks. Biomacromolecules. PMID 28006103 DOI: 10.1021/Acs.Biomac.6B01877 |
0.732 |
|
2016 |
Tych KM, Batchelor M, Hoffmann T, Wilson MC, Hughes ML, Paci E, Brockwell DJ, Dougan L. Differential effects of hydrophobic core packing residues for thermodynamic and mechanical stability of a hyperthermophilic protein. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27338140 DOI: 10.1021/Acs.Langmuir.6B01550 |
0.82 |
|
2016 |
Lenton S, Walsh DL, Rhys NH, Soper AK, Dougan L. Structural evidence for solvent-stabilisation by aspartic acid as a mechanism for halophilic protein stability in high salt concentrations. Physical Chemistry Chemical Physics : Pccp. PMID 27327567 DOI: 10.1039/C6Cp02684B |
0.496 |
|
2016 |
Hughes ML, Dougan L. The physics of pulling polyproteins: a review of single molecule force spectroscopy using the AFM to study protein unfolding. Reports On Progress in Physics. Physical Society (Great Britain). 79: 076601. PMID 27309041 DOI: 10.1088/0034-4885/79/7/076601 |
0.488 |
|
2016 |
Towey JJ, Soper AK, Dougan L. Low-Density Water Structure Observed in a Nanosegregated Cryoprotectant Solution at Low Temperatures from 285 to 238 K. Journal of Physical Chemistry B. 120: 4439-4448. PMID 26991653 DOI: 10.1021/Acs.Jpcb.6B01185 |
0.301 |
|
2016 |
Tych KM, Batchelor M, Hoffmann T, Wilson MC, Paci E, Brockwell DJ, Dougan L. Tuning protein mechanics through an ionic cluster graft from an extremophilic protein. Soft Matter. PMID 26809452 DOI: 10.1039/C5Sm02938D |
0.835 |
|
2015 |
Rhys NH, Soper AK, Dougan L. Hydrophilic Association in a Dilute Glutamine Solution Persists Independent of Increasing Temperature. The Journal of Physical Chemistry. B. 119: 15644-51. PMID 26633573 DOI: 10.1021/Acs.Jpcb.5B07413 |
0.345 |
|
2015 |
Hoffmann T, Tych KM, Crosskey T, Schiffrin B, Brockwell DJ, Dougan L. Rapid and Robust Polyprotein Production Facilitates Single-Molecule Mechanical Characterization of β-Barrel Assembly Machinery Polypeptide Transport Associated Domains. Acs Nano. 9: 8811-21. PMID 26284289 DOI: 10.1021/Acsnano.5B01962 |
0.79 |
|
2015 |
Tych KM, Hoffmann T, Batchelor M, Hughes ML, Kendrick KE, Walsh DL, Wilson M, Brockwell DJ, Dougan L. Life in extreme environments: single molecule force spectroscopy as a tool to explore proteins from extremophilic organisms. Biochemical Society Transactions. 43: 179-85. PMID 25849914 DOI: 10.1042/Bst20140274 |
0.815 |
|
2015 |
Tych KM, Hughes ML, Bourke J, Taniguchi Y, Kawakami M, Brockwell DJ, Dougan L. Optimizing the calculation of energy landscape parameters from single-molecule protein unfolding experiments. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 91: 012710. PMID 25679645 DOI: 10.1103/Physreve.91.012710 |
0.801 |
|
2015 |
Batchelor M, Wolny M, Dougan L, Paci E, Knight PJ, Peckham M. Myosin tails and single α-helical domains. Biochemical Society Transactions. 43: 58-63. PMID 25619246 DOI: 10.1042/Bst20140302 |
0.447 |
|
2015 |
Dougan L. Using Single Molecule Force Spectroscopy to Probe Proteins from Extremophiles Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1966 |
0.62 |
|
2014 |
Wolny M, Batchelor M, Knight PJ, Paci E, Dougan L, Peckham M. Stable single α-helices are constant force springs in proteins. The Journal of Biological Chemistry. 289: 27825-35. PMID 25122759 DOI: 10.1074/Jbc.M114.585679 |
0.461 |
|
2014 |
Wolny M, Batchelor M, Parker F, Baboolal T, Mashanov G, Molloy J, Paci E, Dougan L, Knight PJ, Peckham M. Unravelling the Properties of Single α-Helical Domains in Myosin and other Proteins Biophysical Journal. 106: 626a. DOI: 10.1016/J.Bpj.2013.11.3459 |
0.396 |
|
2013 |
Towey JJ, Soper AK, Dougan L. What happens to the structure of water in cryoprotectant solutions? Faraday Discussions. 167: 159-76. PMID 24640490 DOI: 10.1039/C3Fd00084B |
0.4 |
|
2013 |
Hoffmann T, Tych KM, Hughes ML, Brockwell DJ, Dougan L. Towards design principles for determining the mechanical stability of proteins. Physical Chemistry Chemical Physics : Pccp. 15: 15767-80. PMID 23989058 DOI: 10.1039/C3Cp52142G |
0.825 |
|
2013 |
Hoffmann T, Tych KM, Brockwell DJ, Dougan L. Single-molecule force spectroscopy identifies a small cold shock protein as being mechanically robust. The Journal of Physical Chemistry. B. 117: 1819-26. PMID 23293964 DOI: 10.1021/Jp310442S |
0.846 |
|
2013 |
Tych KM, Hoffmann T, Brockwell DJ, Dougan L. Single molecule force spectroscopy reveals the temperature-dependent robustness and malleability of a hyperthermophilic protein† Soft Matter. 9: 9016-9025. DOI: 10.1039/C3Sm51439K |
0.821 |
|
2013 |
Rhys NH, Dougan L. The emerging role of hydrogen bond interactions in polyglutamine structure, stability and association Soft Matter. 9: 2359-2364. DOI: 10.1039/C2Sm27565A |
0.459 |
|
2012 |
Rhys NH, Soper AK, Dougan L. The Hydrogen-Bonding Ability of the Amino Acid Glutamine Revealed by Neutron Diffraction Experiments Journal of Physical Chemistry B. 116: 13308-13319. PMID 23083424 DOI: 10.1021/Jp307442F |
0.362 |
|
2012 |
Hoffmann T, Dougan L. Single molecule force spectroscopy using polyproteins. Chemical Society Reviews. 41: 4781-96. PMID 22648310 DOI: 10.1039/C2Cs35033E |
0.562 |
|
2012 |
Towey JJ, Dougan L. Structural Examination of the Impact of Glycerol on Water Structure Journal of Physical Chemistry B. 116: 1633-1641. PMID 22126327 DOI: 10.1021/Jp2093862 |
0.351 |
|
2011 |
Dougan L, Genchev GZ, Lu H, Fernandez JM. Probing osmolyte participation in the unfolding transition state of a protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 9759-64. PMID 21613570 DOI: 10.1073/Pnas.1101934108 |
0.712 |
|
2011 |
Towey JJ, Soper AK, Dougan L. Preference for isolated water molecules in a concentrated glycerol-water mixture. Journal of Physical Chemistry B. 115: 7799-7807. PMID 21612256 DOI: 10.1021/Jp203140B |
0.3 |
|
2011 |
Towey JJ, Soper AK, Dougan L. The structure of glycerol in the liquid state: a neutron diffraction study. Physical Chemistry Chemical Physics : Pccp. 13: 9397-406. PMID 21483945 DOI: 10.1039/C0Cp02136A |
0.333 |
|
2010 |
Dougan L, Crain J, Finney JL, Soper AK. Molecular self-assembly in a model amphiphile system. Physical Chemistry Chemical Physics : Pccp. 12: 10221-9. PMID 20539889 DOI: 10.1039/C003407J |
0.604 |
|
2010 |
Dougan L. Self-Assembly in a Model Amphiphile System Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.249 |
0.353 |
|
2010 |
Fernandez JM, Garcia-Manyes S, Dougan L. Force-clamp spectroscopy of single proteins Springer Series in Chemical Physics. 96: 318-335. DOI: 10.1002/9783527626137.ch13 |
0.649 |
|
2009 |
Dougan L, Li J, Badilla CL, Berne BJ, Fernandez JM. Single homopolypeptide chains collapse into mechanically rigid conformations. Proceedings of the National Academy of Sciences of the United States of America. 106: 12605-10. PMID 19549822 DOI: 10.1073/Pnas.0900678106 |
0.665 |
|
2009 |
Garcia-Manyes S, Dougan L, Badilla CL, Brujic J, Fernández JM. Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 106: 10534-9. PMID 19541635 DOI: 10.1073/Pnas.0901213106 |
0.813 |
|
2009 |
Garcia-Manyes S, Dougan L, Fernández JM. Osmolyte-induced separation of the mechanical folding phases of ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 106: 10540-5. PMID 19541633 DOI: 10.1073/Pnas.0902090106 |
0.794 |
|
2009 |
Dougan L, Genchev G, Alegre-Cebollada J, Lu H, Fernandez JM. Solvent Bridging Determines The Molecular Architecture Of The Unfolding Transition State Of A Protein Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.274 |
0.766 |
|
2009 |
Garcia-Manyes S, Dougan L, Badilla CL, Brujic J, Fernandez J. Revisiting Protein Folding at the Single Molecule Level Biophysical Journal. 96: 217a. DOI: 10.1016/J.Bpj.2008.12.1903 |
0.821 |
|
2009 |
Dougan L, Badilla CL, Fernandez JM. Extreme Mechanical Stability In Polyglutamine Chains Identified Using Single Molecule Force-clamp Spectroscopy Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1596 |
0.464 |
|
2008 |
Dougan L, Koti AS, Genchev G, Lu H, Fernandez JM. A single-molecule perspective on the role of solvent hydrogen bonds in protein folding and chemical reactions. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 9: 2836-47. PMID 19058277 DOI: 10.1002/Cphc.200800572 |
0.628 |
|
2008 |
Koti Ainavarapu SR, Wiita AP, Dougan L, Uggerud E, Fernandez JM. Single-molecule force spectroscopy measurements of bond elongation during a bimolecular reaction. Journal of the American Chemical Society. 130: 6479-87. PMID 18433129 DOI: 10.1021/Ja800180U |
0.739 |
|
2008 |
Dougan L, Feng G, Lu H, Fernandez JM. Solvent molecules bridge the mechanical unfolding transition state of a protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 3185-90. PMID 18305176 DOI: 10.1073/Pnas.0706075105 |
0.672 |
|
2007 |
Dougan L, Fernandez JM. Tandem repeating modular proteins avoid aggregation in single molecule force spectroscopy experiments. The Journal of Physical Chemistry. A. 111: 12402-8. PMID 18020430 DOI: 10.1021/Jp076095+ |
0.684 |
|
2007 |
Walther KA, Gräter F, Dougan L, Badilla CL, Berne BJ, Fernandez JM. Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 104: 7916-21. PMID 17470816 DOI: 10.1073/Pnas.0702179104 |
0.818 |
|
2006 |
Soper AK, Dougan L, Crain J, Finney JL. Excess entropy in alcohol-water solutions: a simple clustering explanation. The Journal of Physical Chemistry. B. 110: 3472-6. PMID 16494400 DOI: 10.1021/Jp054556Q |
0.578 |
|
2005 |
Dougan L, Hargreaves R, Bates SP, Finney JL, Réat V, Soper AK, Crain J. Segregation in aqueous methanol enhanced by cooling and compression. The Journal of Chemical Physics. 122: 174514. PMID 15910052 DOI: 10.1063/1.1888405 |
0.587 |
|
2004 |
Dougan L, Crain J, Vass H, Magennis SW. Probing the liquid-state structure and dynamics of aqueous solutions by fluorescence spectroscopy. Journal of Fluorescence. 14: 91-7. PMID 15622867 DOI: 10.1023/B:Jofl.0000014666.03818.A4 |
0.587 |
|
2004 |
Dougan L, Bates SP, Hargreaves R, Fox JP, Crain J, Finney JL, Reat V, Soper AK. Methanol-water solutions: a bi-percolating liquid mixture. The Journal of Chemical Physics. 121: 6456-62. PMID 15446945 DOI: 10.1063/1.1789951 |
0.59 |
|
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