Fabien Pierrel - Publications

Affiliations: 
2001-2004 CEA-Grenoble 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ferizhendi KK, Simon P, Pelosi L, Séchet E, Arulanandam R, Chehade MH, Rey M, Onal D, Flandrin L, Chreim R, Faivre B, Vo SC, Arias-Cartin R, Barras F, Fontecave M, ... ... Pierrel F, et al. An organic O donor for biological hydroxylation reactions. Proceedings of the National Academy of Sciences of the United States of America. 121: e2321242121. PMID 38507448 DOI: 10.1073/pnas.2321242121  0.602
2024 Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, ... ... Pierrel F, et al. COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells. Molecular Cell. PMID 38295803 DOI: 10.1016/j.molcel.2024.01.003  0.349
2023 Gonzalez L, Chau-Duy Tam Vo S, Faivre B, Pierrel F, Fontecave M, Hamdane D, Lombard M. Activation of Coq6p, a FAD Monooxygenase Involved in Coenzyme Q Biosynthesis, by Adrenodoxin Reductase/Ferredoxin. Chembiochem : a European Journal of Chemical Biology. e202300738. PMID 38141230 DOI: 10.1002/cbic.202300738  0.721
2023 Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, ... ... Pierrel F, et al. COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells. Biorxiv : the Preprint Server For Biology. PMID 38014142 DOI: 10.1101/2023.11.13.566839  0.336
2023 Kazemzadeh K, Pelosi L, Chenal C, Chobert SC, Hajj Chehade M, Jullien M, Flandrin L, Schmitt W, He Q, Bouvet E, Jarzynka M, Varoquaux N, Junier I, Pierrel F, Abby SS. Diversification of Ubiquinone Biosynthesis via Gene Duplications, Transfers, Losses, and Parallel Evolution. Molecular Biology and Evolution. 40. PMID 37788637 DOI: 10.1093/molbev/msad219  0.311
2022 Schulz V, Basu S, Freibert SA, Webert H, Boss L, Mühlenhoff U, Pierrel F, Essen LO, Warui DM, Booker SJ, Stehling O, Lill R. Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2. Nature Chemical Biology. PMID 36280795 DOI: 10.1038/s41589-022-01159-4  0.312
2022 Pierrel F, Burgardt A, Lee JH, Pelosi L, Wendisch VF. Recent advances in the metabolic pathways and microbial production of coenzyme Q. World Journal of Microbiology & Biotechnology. 38: 58. PMID 35178585 DOI: 10.1007/s11274-022-03242-3  0.3
2021 Arias-Cartin R, Uzel A, Seduk F, Gerbaud G, Pierrel F, Broc M, Lebrun R, Guigliarelli B, Magalon A, Grimaldi S, Walburger A. Identification and characterization of a non-canonical menaquinone-linked formate dehydrogenase. The Journal of Biological Chemistry. 101384. PMID 34748728 DOI: 10.1016/j.jbc.2021.101384  0.369
2020 Abby SS, Kazemzadeh K, Vragniau C, Pelosi L, Pierrel F. Advances in bacterial pathways for the biosynthesis of ubiquinone. Biochimica Et Biophysica Acta. Bioenergetics. 1861: 148259. PMID 32663475 DOI: 10.1016/J.Bbabio.2020.148259  0.427
2020 Szyttenholm J, Chaspoul F, Bauzan M, Ducluzeau AL, Chehade MH, Pierrel F, Denis Y, Nitschke W, Schoepp-Cothenet B. The controversy on the ancestral arsenite oxidizing enzyme; deducing evolutionary histories with phylogeny and thermodynamics. Biochimica Et Biophysica Acta. Bioenergetics. 1861: 148252. PMID 32569664 DOI: 10.1016/J.Bbabio.2020.148252  0.408
2020 Vo CD, Michaud J, Elsen S, Faivre B, Bouveret E, Barras F, Fontecave M, Pierrel F, Lombard M, Pelosi L. The O-independent pathway of ubiquinone biosynthesis is essential for denitrification in . The Journal of Biological Chemistry. PMID 32409583 DOI: 10.1074/Jbc.Ra120.013748  0.726
2019 Acosta Lopez MJ, Trevisson E, Canton M, Vazquez-Fonseca L, Morbidoni V, Baschiera E, Frasson C, Pelosi L, Rascalou B, Desbats MA, Alcázar-Fabra M, Ríos JJ, Sánchez-García A, Basso G, Navas P, ... Pierrel F, et al. Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking . Oxidative Medicine and Cellular Longevity. 2019: 3904905. PMID 31379988 DOI: 10.1155/2019/3904905  0.433
2019 Pelosi L, Vo CD, Abby SS, Loiseau L, Rascalou B, Hajj Chehade M, Faivre B, Goussé M, Chenal C, Touati N, Binet L, Cornu D, Fyfe CD, Fontecave M, Barras F, ... ... Pierrel F, et al. Ubiquinone Biosynthesis over the Entire O Range: Characterization of a Conserved O-Independent Pathway. Mbio. 10. PMID 31289180 DOI: 10.1128/Mbio.01319-19  0.679
2019 Cerqua C, Casarin A, Pierrel F, Vazquez Fonseca L, Viola G, Salviati L, Trevisson E. Vitamin K2 cannot substitute Coenzyme Q as electron carrier in the mitochondrial respiratory chain of mammalian cells. Scientific Reports. 9: 6553. PMID 31024065 DOI: 10.1038/S41598-019-43014-Y  0.382
2018 Hajj Chehade M, Pelosi L, Fyfe CD, Loiseau L, Rascalou B, Brugière S, Kazemzadeh K, Vo CD, Ciccone L, Aussel L, Couté Y, Fontecave M, Barras F, Lombard M, Pierrel F. A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone. Cell Chemical Biology. PMID 30686758 DOI: 10.1016/J.Chembiol.2018.12.001  0.718
2017 Pierrel F. Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency. Frontiers in Physiology. 8: 436. PMID 28690551 DOI: 10.3389/Fphys.2017.00436  0.447
2017 Loiseau L, Fyfe C, Aussel L, Hajj Chehade M, Hernández SB, Faivre B, Hamdane D, Mellot-Draznieks C, Rascalou B, Pelosi L, Velours C, Cornu D, Lombard M, Casadesús J, Pierrel F, et al. The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ. The Journal of Biological Chemistry. PMID 28559279 DOI: 10.1074/Jbc.M117.789164  0.722
2016 Pelosi L, Ducluzeau AL, Loiseau L, Barras F, Schneider D, Junier I, Pierrel F. Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions. Msystems. 1. PMID 27822549 DOI: 10.1128/mSystems.00091-16  0.356
2016 Payet LA, Leroux M, Willison JC, Kihara A, Pelosi L, Pierrel F. Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast. Cell Chemical Biology. PMID 27693056 DOI: 10.1016/J.Chembiol.2016.08.008  0.481
2016 Stefely JA, Licitra F, Laredj L, Reidenbach AG, Kemmerer ZA, Grangeray A, Jaeg-Ehret T, Minogue CE, Ulbrich A, Hutchins PD, Wilkerson EM, Ruan Z, Aydin D, Hebert AS, Guo X, ... ... Pierrel F, et al. Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. Molecular Cell. PMID 27499294 DOI: 10.1016/J.Molcel.2016.06.030  0.346
2016 Andrea Desbats M, Morbidoni V, Silic-Benussi M, Doimo M, Ciminale V, Cassina M, Sacconi S, Hirano M, Basso G, Pierrel F, Navas P, Salviati L, Trevisson E. The COQ2 genotype predicts the severity of Coenzyme Q10 deficiency. Human Molecular Genetics. PMID 27493029 DOI: 10.1093/Hmg/Ddw257  0.419
2016 Ismail A, Leroux V, Smadja M, Gonzalez L, Lombard M, Pierrel F, Mellot-Draznieks C, Fontecave M. Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6. Plos Computational Biology. 12: e1004690. PMID 26808124 DOI: 10.1371/Journal.Pcbi.1004690  0.718
2016 Payet L, Leroux M, Willison JC, Kihara A, Pelosi L, Pierrel F. Characterization of metabolic steps involved in the biosynthesis of the precursor of coenzyme Q in Saccharomyces cerevisiae Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1857: e50. DOI: 10.1016/J.Bbabio.2016.04.145  0.421
2015 Ozeir M, Pelosi L, Ismail A, Mellot-Draznieks C, Fontecave M, Pierrel F. Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 290: 24140-51. PMID 26260787 DOI: 10.1074/Jbc.M115.675744  0.662
2015 Rendon J, Pilet E, Fahs Z, Seduk F, Sylvi L, Hajj Chehade M, Pierrel F, Guigliarelli B, Magalon A, Grimaldi S. Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site. Biochimica Et Biophysica Acta. 1847: 739-47. PMID 25976528 DOI: 10.1016/J.Bbabio.2015.05.001  0.422
2014 Brazzolotto X, Pierrel F, Pelosi L. Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins Biochemical Journal. 460: 79-89. PMID 24624902 DOI: 10.1042/Bj20140107  0.384
2014 Aussel L, Pierrel F, Loiseau L, Lombard M, Fontecave M, Barras F. Biosynthesis and physiology of coenzyme Q in bacteria Biochimica Et Biophysica Acta - Bioenergetics. 1837: 1004-1011. PMID 24480387 DOI: 10.1016/J.Bbabio.2014.01.015  0.728
2014 Aussel L, Loiseau L, Chehade MH, Pocachard B, Fontecave M, Pierrel F, Barras F. UbiJ, a new gene required for aerobic growth and proliferation in macrophage, is involved in coenzyme q biosynthesis in Escherichia coli and Salmonella enterica serovar typhimurium Journal of Bacteriology. 196: 70-79. PMID 24142253 DOI: 10.1128/Jb.01065-13  0.67
2014 Doimo M, Trevisson E, Airik R, Bergdoll M, Santos-Ocaña C, Hildebrandt F, Navas P, Pierrel F, Salviati L. Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1842: 1-6. PMID 24140869 DOI: 10.1016/J.Bbadis.2013.10.007  0.39
2014 Schoepp-Cothenet B, Bauzan M, Ducluzeau A, Pierrel F, Nitschke W. Study of the respiratory arsenate reductase from Halorhodospira halophila definitively clarifies the evolutionary history of this versatile enzyme Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e90-e91. DOI: 10.1016/J.Bbabio.2014.05.107  0.365
2013 Chehade MH, Loiseau L, Lombard M, Pecqueur L, Ismail A, Smadja M, Golinelli-Pimpaneau B, Mellot-Draznieks C, Hamelin O, Aussel L, Kieffer-Jaquinod S, Labessan N, Barras F, Fontecave M, Pierrel F. Ubil, a new gene in escherichia coli coenzyme Q biosynthesis, is involved in aerobic C5-hydroxylation Journal of Biological Chemistry. 288: 20085-20092. PMID 23709220 DOI: 10.1074/Jbc.M113.480368  0.743
2012 Xie LX, Ozeir M, Tang JY, Chen JY, Jaquinod SK, Fontecave M, Clarke CF, Pierrel F. Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway. The Journal of Biological Chemistry. 287: 23571-81. PMID 22593570 DOI: 10.1074/Jbc.M112.360354  0.662
2012 Ozeir M, Xie LX, Chehade MH, Tang JY, Chen JY, Jaquinod S, Fontecave M, Clarke CF, Pierrel F. In vivo accumulation of coenzyme Q biosynthetic intermediates and aminated analogs in the yeast Saccharomyces cerevisiae Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1817: S92. DOI: 10.1016/J.Bbabio.2012.06.249  0.657
2011 Ozeir M, Mühlenhoff U, Webert H, Lill R, Fontecave M, Pierrel F. Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency. Chemistry & Biology. 18: 1134-42. PMID 21944752 DOI: 10.1016/J.Chembiol.2011.07.008  0.68
2010 Mühlenhoff U, Molik S, Godoy JR, Uzarska MA, Richter N, Seubert A, Zhang Y, Stubbe J, Pierrel F, Herrero E, Lillig CH, Lill R. Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metabolism. 12: 373-85. PMID 20889129 DOI: 10.1016/J.Cmet.2010.08.001  0.379
2010 Pierrel F, Hamelin O, Douki T, Kieffer-Jaquinod S, Mühlenhoff U, Ozeir M, Lill R, Fontecave M. Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis. Chemistry & Biology. 17: 449-59. PMID 20534343 DOI: 10.1016/J.Chembiol.2010.03.014  0.672
2010 Bestwick M, Khalimonchuk O, Pierrel F, Winge DR. The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10 Molecular and Cellular Biology. 30: 172-185. PMID 19841065 DOI: 10.1128/Mcb.00869-09  0.419
2008 Pierrel F, Khalimonchuk O, Cobine PA, Bestwick M, Winge DR. Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1 Molecular and Cellular Biology. 28: 4927-4939. PMID 18541668 DOI: 10.1128/Mcb.00057-08  0.39
2008 Khalimonchuk O, Rigby K, Bestwick M, Pierrel F, Cobine PA, Winge DR. Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae Eukaryotic Cell. 7: 1427-1431. PMID 18503002 DOI: 10.1128/Ec.00132-08  0.321
2007 Pierrel F, Bestwick ML, Cobine PA, Khalimonchuk O, Cricco JA, Winge DR. Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly Embo Journal. 26: 4335-4346. PMID 17882260 DOI: 10.1038/Sj.Emboj.7601861  0.354
2007 Mathevon C, Pierrel F, Oddou JL, Garcia-Serres R, Blondin G, Latour JM, Ménage S, Gambarelli S, Fontecave M, Atta M. tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase Proceedings of the National Academy of Sciences of the United States of America. 104: 13295-13300. PMID 17679698 DOI: 10.1073/Pnas.0704338104  0.757
2007 Hernández HL, Pierrel F, Elleingand E, García-Serres R, Huynh BH, Johnson MK, Fontecave M, Atta M. MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters. Biochemistry. 46: 5140-7. PMID 17407324 DOI: 10.1021/Bi7000449  0.737
2006 Cobine PA, Pierrel F, Leary SC, Sasarman F, Horng YC, Shoubridge EA, Winge DR. The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding Journal of Biological Chemistry. 281: 12270-12276. PMID 16520371 DOI: 10.1074/Jbc.M600496200  0.33
2004 Pierrel F, Douki T, Fontecave M, Atta M. MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA Journal of Biological Chemistry. 279: 47555-47563. PMID 15339930 DOI: 10.1074/Jbc.M408562200  0.74
2003 Pierrel F, Hernandez HL, Johnson MK, Fontecave M, Atta M. MiaB protein from Thermotoga maritima. Characterization of an extremely thermophilic tRNA-methylthiotransferase. The Journal of Biological Chemistry. 278: 29515-24. PMID 12766153 DOI: 10.1074/Jbc.M301518200  0.758
2002 Pierrel F, Björk GR, Fontecave M, Atta M. Enzymatic modification of tRNAs. MiaB is an iron-sulfur protein Journal of Biological Chemistry. 277: 13367-13370. PMID 11882645 DOI: 10.1074/Jbc.C100609200  0.749
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