Michael P. Murphy
Affiliations: | MRC Mitochondrial Biology Unit | University of Cambridge, Cambridge, England, United Kingdom |
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"Michael Murphy"
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| Miljkovic JL, Burger N, Gawel JM, et al. (2022) Rapid and selective generation of HS within mitochondria protects against cardiac ischemia-reperfusion injury. Redox Biology. 55: 102429 |
| Prag HA, Aksentijevic D, Dannhorn A, et al. (2022) Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury. Circulation Research. 101161CIRCRESAHA1213 |
| Gruszczyk AV, Casey AM, James AM, et al. (2022) Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. Redox Biology. 54: 102368 |
| Yin Z, Burger N, Kula-Alwar D, et al. (2021) Structural basis for a complex I mutation that blocks pathological ROS production. Nature Communications. 12: 707 |
| Deragon MA, McCaig WD, Patel PS, et al. (2020) Mitochondrial ROS prime the hyperglycemic shift from apoptosis to necroptosis. Cell Death Discovery. 6: 132 |
| Cvetko F, Caldwell ST, Higgins M, et al. (2020) Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. The Journal of Biological Chemistry |
| Prag HA, Gruszczyk AV, Huang MM, et al. (2020) Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovascular Research |
| Prag HA, Pala L, Kula-Alwar D, et al. (2020) Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovascular Drugs and Therapy |
| Chowdhury AR, Zielonka J, Kalyanaraman B, et al. (2020) Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon. Redox Biology. 36: 101606 |
| Fortner KA, Blanco LP, Buskiewicz I, et al. (2020) Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- mice. Lupus Science & Medicine. 7 |