Victor A. Kenyon, Ph.D. - Publications

Affiliations: 
University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
biophysical methods to study neurological proteins, their cofactors and how misregulation contributes to disease

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Alkan C, O'Brien T, Kenyon V, Ikegami T. Computer-Selected Antiviral Compounds: Assessing In Vitro Efficacies against Rift Valley Fever Virus. Viruses. 16. PMID 38257788 DOI: 10.3390/v16010088  0.303
2015 Jameson JB, Kenyon V, Holman TR. A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors. Analytical Biochemistry. 476: 45-50. PMID 25712042 DOI: 10.1016/J.Ab.2015.02.011  0.451
2014 Armstrong MM, Diaz G, Kenyon V, Holman TR. Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes. Bioorganic & Medicinal Chemistry. 22: 4293-7. PMID 24924423 DOI: 10.1016/J.Bmc.2014.05.025  0.39
2014 Rai G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, et al. Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies. Journal of Medicinal Chemistry. 57: 4035-48. PMID 24684213 DOI: 10.1021/Jm401915R  0.559
2012 Weaver JR, Holman TR, Imai Y, Jadhav A, Kenyon V, Maloney DJ, Nadler JL, Rai G, Simeonov A, Taylor-Fishwick DA. Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction. Molecular and Cellular Endocrinology. 358: 88-95. PMID 22502743 DOI: 10.1016/J.Mce.2012.03.004  0.305
2012 Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M. Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation Molecular Pharmacology. 81: 420-430. PMID 22155783 DOI: 10.1124/Mol.111.075630  0.398
2011 Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, et al. Discovery of potent and selective inhibitors of human platelet-type 12-lipoxygenase Journal of Medicinal Chemistry. 54: 5485-5497. PMID 21739938 DOI: 10.1021/Jm2005089  0.588
2010 Rai G, Kenyon V, Jadhav A, Schultz L, Armstrong M, Jameson JB, Hoobler E, Leister W, Simeonov A, Holman TR, Maloney DJ. Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1 Journal of Medicinal Chemistry. 53: 7392-7404. PMID 20866075 DOI: 10.1021/Jm1008852  0.569
2009 Wecksler AT, Kenyon V, Garcia NK, Deschamps JD, Van Der Donk WA, Holman TR. Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2 Biochemistry. 48: 8721-8730. PMID 19645454 DOI: 10.1021/Bi9009242  0.326
2008 van Leyen K, Arai K, Jin G, Kenyon V, Gerstner B, Rosenberg PA, Holman TR, Lo EH. Novel lipoxygenase inhibitors as neuroprotective reagents. Journal of Neuroscience Research. 86: 904-9. PMID 17960827 DOI: 10.1002/jnr.21543  0.38
2007 Vasquez-Martinez Y, Ohri RV, Kenyon V, Holman TR, Sepúlveda-Boza S. Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2 Bioorganic and Medicinal Chemistry. 15: 7408-7425. PMID 17869117 DOI: 10.1016/J.Bmc.2007.07.036  0.508
2006 Deschamps JD, Kenyon VA, Holman TR. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases Bioorganic and Medicinal Chemistry. 14: 4295-4301. PMID 16500106 DOI: 10.1016/J.Bmc.2006.01.057  0.539
2006 Kenyon V, Chorny I, Carvajal WJ, Holman TR, Jacobson MP. Novel human lipoxygenase inhibitors discovered using virtual screening with homology models Journal of Medicinal Chemistry. 49: 1356-1363. PMID 16480270 DOI: 10.1021/Jm050639J  0.553
2005 Cichewicz RH, Clifford LJ, Lassen PR, Cao X, Freedman TB, Nafie LA, Deschamps JD, Kenyon VA, Flanary JR, Holman TR, Crews P. Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis. Bioorganic & Medicinal Chemistry. 13: 5600-12. PMID 16039133 DOI: 10.1016/J.Bmc.2005.06.020  0.343
2004 Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: Archetypes for a unique class of selective and recyclable inhibitors Journal of the American Chemical Society. 126: 14910-14920. PMID 15535718 DOI: 10.1021/Ja046082Z  0.561
2004 Ruddat VC, Mogul R, Chorny I, Chen C, Perrin N, Whitman S, Kenyon V, Jacobson MP, Bernasconi CF, Holman TR. Tryptophan 500 and arginine 707 define product and substrate active site binding in soybean lipoxygenase-1 Biochemistry. 43: 13063-13071. PMID 15476400 DOI: 10.1021/Bi0489098  0.305
2004 Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. Journal of Medicinal Chemistry. 47: 4060-5. PMID 15267244 DOI: 10.1021/Jm049872S  0.476
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