Year |
Citation |
Score |
2014 |
Rai G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, et al. Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies. Journal of Medicinal Chemistry. 57: 4035-48. PMID 24684213 DOI: 10.1021/Jm401915R |
0.515 |
|
2014 |
Luci DK, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, et al. Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. Journal of Medicinal Chemistry. 57: 495-506. PMID 24393039 DOI: 10.1021/Jm4016476 |
0.456 |
|
2013 |
Joshi N, Hoobler EK, Perry S, Diaz G, Fox B, Holman TR. Kinetic and structural investigations into the allosteric and pH effect on the substrate specificity of human epithelial 15-lipoxygenase-2. Biochemistry. 52: 8026-35. PMID 24171444 DOI: 10.1021/Bi4010649 |
0.304 |
|
2013 |
Yigitkanli K, Pekcec A, Karatas H, Pallast S, Mandeville E, Joshi N, Smirnova N, Gazaryan I, Ratan RR, Witztum JL, Montaner J, Holman TR, Lo EH, van Leyen K. Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke. Annals of Neurology. 73: 129-35. PMID 23192915 DOI: 10.1002/Ana.23734 |
0.447 |
|
2011 |
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, et al. Discovery of potent and selective inhibitors of human platelet-type 12-lipoxygenase Journal of Medicinal Chemistry. 54: 5485-5497. PMID 21739938 DOI: 10.1021/Jm2005089 |
0.512 |
|
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