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Jeremy P. Mallari, Ph.D. - Publications

Affiliations: 
2008 Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Area:
Pharmaceutical Chemistry
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Eagon S, Howland M, Heying M, Callant E, Brar N, Pompa E, Mallari JP. Identification of Plasmodium falciparum falcilysin inhibitors by a virtual screen. Bioorganic & Medicinal Chemistry Letters. 52: 128394. PMID 34606998 DOI: 10.1016/j.bmcl.2021.128394  0.318
2021 Kahlon G, Lira R, Masvlov N, Pompa E, Brar N, Eagon S, Anderson MO, Andaya A, Chance JP, Fejzic H, Keniston A, Huynh N, Celis N, Vidal B, Trieu N, ... ... Mallari JP, et al. Corrigendum to "Structure guided development of potent piperazine-derived hydroxamic acid inhibitors targeting falcilysin" [Bioorg. Med. Chem. Lett. 32 (2021) 127683]. Bioorganic & Medicinal Chemistry Letters. 37: 127836. PMID 33588181 DOI: 10.1016/j.bmcl.2021.127836  0.579
2020 Kahlon G, Lira R, Masvlov N, Pompa E, Brar N, Eagon S, Anderson MO, Andaya A, Chance JP, Fejzic H, Keniston A, Vidal B, Trieu N, Rodriguez P, Mallari JP. Structure Guided Development of Potent Piperazine-Derived Hydroxamic Acid Inhibitors Targeting Falcilysin. Bioorganic & Medicinal Chemistry Letters. 127683. PMID 33227414 DOI: 10.1016/j.bmcl.2020.127683  0.625
2018 Chance JP, Fejzic H, Hernandez O, Istvan ES, Andaya A, Maslov N, Aispuro R, Crisanto T, Nguyen H, Vidal B, Serrano W, Kuwahara B, Pugne Andanado C, Goldberg DE, Mallari JP. Development of piperazine-based hydroxamic acid inhibitors against falcilysin, an essential malarial protease. Bioorganic & Medicinal Chemistry Letters. PMID 29691139 DOI: 10.1016/J.Bmcl.2018.04.010  0.518
2017 Istvan ES, Mallari JP, Corey VC, Dharia NV, Marshall GR, Winzeler EA, Goldberg DE. Esterase mutation is a mechanism of resistance to antimalarial compounds. Nature Communications. 8: 14240. PMID 28106035 DOI: 10.1038/Ncomms14240  0.32
2011 Zhang F, Tagen M, Throm S, Mallari J, Miller L, Guy RK, Dyer MA, Williams RT, Roussel MF, Nemeth K, Zhu F, Zhang J, Lu M, Panetta JC, Boulos N, et al. Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 15-21. PMID 20947617 DOI: 10.1124/Dmd.110.035915  0.449
2010 Mallari JP, Zhu F, Lemoff A, Kaiser M, Lu M, Brun R, Guy RK. Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models. Bioorganic & Medicinal Chemistry. 18: 8302-9. PMID 21051236 DOI: 10.1016/J.Bmc.2010.09.073  0.605
2009 Mallari JP, Shelat AA, Kosinski A, Caffrey CR, Connelly M, Zhu F, McKerrow JH, Guy RK. Structure-guided development of selective TbcatB inhibitors. Journal of Medicinal Chemistry. 52: 6489-93. PMID 19769357 DOI: 10.1021/Jm900908P  0.668
2009 Mallari JP, Guiguemde WA, Guy RK. Antimalarial activity of thiosemicarbazones and purine derived nitriles. Bioorganic & Medicinal Chemistry Letters. 19: 3546-9. PMID 19447616 DOI: 10.1016/J.Bmcl.2009.04.142  0.638
2008 Mallari JP, Shelat A, Kosinski A, Caffrey CR, Connelly M, Zhu F, McKerrow JH, Guy RK. Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB. Bioorganic & Medicinal Chemistry Letters. 18: 2883-5. PMID 18420405 DOI: 10.1016/J.Bmcl.2008.03.083  0.656
2008 Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. Journal of Medicinal Chemistry. 51: 545-52. PMID 18173229 DOI: 10.1021/Jm070760L  0.654
2006 MacKey ZB, Baca AM, Mallari JP, Apsel B, Shelat A, Hansell EJ, Chiang PK, Wolff B, Guy KR, Williams J, McKerrow JH. Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei Chemical Biology and Drug Design. 67: 355-363. PMID 16784460 DOI: 10.1111/J.1747-0285.2006.00389.X  0.551
2005 Fujii N, Mallari JP, Hansell EJ, Mackey Z, Doyle P, Zhou YM, Gut J, Rosenthal PJ, McKerrow JH, Guy RK. Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain. Bioorganic & Medicinal Chemistry Letters. 15: 121-3. PMID 15582423 DOI: 10.1016/J.Bmcl.2004.10.023  0.624
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