| Year |
Citation |
Score |
| 2023 |
Bergagnini-Kolev MC, Hsu S, Aitken ML, Goss CH, Hoofnagle AN, Zelnick LR, Lum D, Best CM, Thummel KE, Kestenbaum BR, de Boer IH, Lin YS. Metabolism and pharmacokinetics of vitamin D in patients with cystic fibrosis. The Journal of Steroid Biochemistry and Molecular Biology. 232: 106332. PMID 37217104 DOI: 10.1016/j.jsbmb.2023.106332 |
0.494 |
|
| 2022 |
Best CM, Thummel KE, Hsu S, Lin Y, Zelnick LR, Kestenbaum B, Kushnir MM, de Boer IH, Hoofnagle AN. The plasma free fraction of 25-hydroxyvitamin D is not strongly associated with 25-hydroxyvitamin D clearance in kidney disease patients and controls. The Journal of Steroid Biochemistry and Molecular Biology. 226: 106206. PMID 36404469 DOI: 10.1016/j.jsbmb.2022.106206 |
0.505 |
|
| 2021 |
Hsu S, Zelnick LR, Lin YS, Best CM, Kestenbaum BR, Thummel KE, Hoofnagle AN, de Boer IH. Validation of the 24,25-dihydroxyvitamin D to 25-hydroxyvitamin D ratio as a biomarker of 25-hydroxyvitamin D clearance. The Journal of Steroid Biochemistry and Molecular Biology. 106047. PMID 34954017 DOI: 10.1016/j.jsbmb.2021.106047 |
0.507 |
|
| 2021 |
Lin YS, Thummel KE, Thompson BD, Totah RA, Cho CW. Sources of Interindividual Variability. Methods in Molecular Biology (Clifton, N.J.). 2342: 481-550. PMID 34272705 DOI: 10.1007/978-1-0716-1554-6_17 |
0.553 |
|
| 2020 |
Hsu S, Zelnick LR, Lin YS, Best CM, Kestenbaum B, Thummel KE, Rose LM, Hoofnagle AN, de Boer IH. Differences in 25-Hydroxyvitamin D Clearance by eGFR and Race: A Pharmacokinetic Study. Journal of the American Society of Nephrology : Jasn. PMID 33115916 DOI: 10.1681/ASN.2020050625 |
0.505 |
|
| 2020 |
Chen KF, Chan LN, Lin YS. PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery. Journal of Pharmacokinetics and Pharmacodynamics. PMID 32710209 DOI: 10.1007/S10928-020-09701-4 |
0.406 |
|
| 2020 |
Chen KF, Chan LN, Senn TD, Oelschlager BK, Flum DR, Shen DD, Horn JR, Lin YS. The Impact of Proximal Roux-en-Y Gastric Bypass Surgery on Acetaminophen Absorption and Metabolism. Pharmacotherapy. PMID 31960977 DOI: 10.1002/Phar.2368 |
0.353 |
|
| 2020 |
Zhang H, Basit A, Wolford C, Chen KF, Gaedigk A, Lin YS, Leeder JS, Prasad B. Normalized testosterone glucuronide (TG/AG) as a potential urinary biomarker for highly variable UGT2B17 in children 7 to 18 years. Clinical Pharmacology and Therapeutics. PMID 31900930 DOI: 10.1002/Cpt.1764 |
0.319 |
|
| 2017 |
Gao C, Bergagnini-Kolev MC, Liao MZ, Wang Z, Wong T, Calamia JC, Lin YS, Mao Q, Thummel KE. Simultaneous quantification of 25-hydroxyvitamin D3-3-sulfate and 25-hydroxyvitamin D3-3-glucuronide in human serum and plasma using liquid chromatography-tandem mass spectrometry coupled with DAPTAD-derivatization. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1060: 158-165. PMID 28622619 DOI: 10.1016/J.Jchromb.2017.06.017 |
0.556 |
|
| 2016 |
Mao J, Martin I, McLeod J, Nolan G, van Horn R, Vourvahis M, Lin YS. Perspective: 4β-Hydroxycholesterol as an Emerging Endogenous Biomarker of Hepatic CYP3A. Drug Metabolism Reviews. 1-49. PMID 27718639 DOI: 10.1080/03602532.2016.1239630 |
0.376 |
|
| 2015 |
Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS. Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26681736 DOI: 10.1124/Dmd.115.067900 |
0.631 |
|
| 2015 |
Brown JT, Abdel-Rahman SM, van Haandel L, Gaedigk A, Lin YS, Leeder JS. Single Dose, CYP2D6 Genotype-Stratified Pharmacokinetic Study of Atomoxetine in Children with ADHD. Clinical Pharmacology and Therapeutics. PMID 26660002 DOI: 10.1002/Cpt.319 |
0.325 |
|
| 2015 |
Yasuda K, Cline C, Lin YS, Scheib R, Ganguly S, Thirumaran R, Chaudhry AS, Kim RB, Schuetz EG. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26281846 DOI: 10.1124/Dmd.115.065078 |
0.307 |
|
| 2015 |
Chan LN, Lin YS, Tay-Sontheimer JC, Trawick D, Oelschlager BK, Flum DR, Patton KK, Shen DD, Horn JR. Proximal Roux-en-Y gastric bypass alters drug absorption pattern but not systemic exposure of CYP3A4 and P-glycoprotein substrates. Pharmacotherapy. 35: 361-9. PMID 25757445 DOI: 10.1002/Phar.1560 |
0.341 |
|
| 2014 |
Tay-Sontheimer J, Shireman LM, Beyer RP, Senn T, Witten D, Pearce RE, Gaedigk A, Gana Fomban CL, Lutz JD, Isoherranen N, Thummel KE, Fiehn O, Leeder JS, Lin YS. Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics. Pharmacogenomics. 15: 1947-62. PMID 25521354 DOI: 10.2217/Pgs.14.155 |
0.53 |
|
| 2014 |
de Boer IH, Sachs MC, Chonchol M, Himmelfarb J, Hoofnagle AN, Ix JH, Kremsdorf RA, Lin YS, Mehrotra R, Robinson-Cohen C, Siscovick DS, Steffes MW, Thummel KE, Tracy RP, Wang Z, et al. Estimated GFR and circulating 24,25-dihydroxyvitamin D3 concentration: a participant-level analysis of 5 cohort studies and clinical trials. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 64: 187-97. PMID 24703961 DOI: 10.1053/J.Ajkd.2014.02.015 |
0.54 |
|
| 2014 |
McWilliam SJ, Antoine DJ, Sabbisetti V, Pearce RE, Jorgensen AL, Lin Y, Leeder JS, Bonventre JV, Smyth RL, Pirmohamed M. Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children. Biomarkers in Medicine. 8: 1189-97. PMID 24661102 DOI: 10.2217/Bmm.14.36 |
0.302 |
|
| 2014 |
Thummel KE, Lin YS. Sources of interindividual variability. Methods in Molecular Biology (Clifton, N.J.). 1113: 363-415. PMID 24523121 DOI: 10.1007/978-1-62703-758-7_17 |
0.61 |
|
| 2014 |
Brantley SJ, Argikar AA, Lin YS, Nagar S, Paine MF. Herb-drug interactions: challenges and opportunities for improved predictions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 301-17. PMID 24335390 DOI: 10.1124/Dmd.113.055236 |
0.308 |
|
| 2013 |
Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition. Transplantation. 95: 821-7. PMID 23354298 DOI: 10.1097/Tp.0B013E31827E6Ad9 |
0.592 |
|
| 2013 |
Prasad B, Lai Y, Lin Y, Unadkat JD. Interindividual variability in the hepatic expression of the human breast cancer resistance protein (BCRP/ABCG2): effect of age, sex, and genotype. Journal of Pharmaceutical Sciences. 102: 787-93. PMID 23280364 DOI: 10.1002/Jps.23436 |
0.423 |
|
| 2013 |
Wang Z, Lin YS, Dickmann LJ, Poulton EJ, Eaton DL, Lampe JW, Shen DD, Davis CL, Shuhart MC, Thummel KE. Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1101-16. PMID 23212742 DOI: 10.1002/Jbmr.1839 |
0.639 |
|
| 2013 |
Baker PE, Cole TB, Cartwright M, Suzuki SM, Thummel KE, Lin YS, Co AL, Rettie AE, Kim JH, Furlong CE. Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants. Chemico-Biological Interactions. 203: 257-64. PMID 23085349 DOI: 10.1016/J.Cbi.2012.10.005 |
0.573 |
|
| 2012 |
Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. Measurement and compartmental modeling of the effect of CYP3A5 gene variation on systemic and intrarenal tacrolimus disposition. Clinical Pharmacology and Therapeutics. 92: 737-45. PMID 23073208 DOI: 10.1038/Clpt.2012.175 |
0.644 |
|
| 2012 |
Zheng XE, Wang Z, Liao MZ, Lin YS, Shuhart MC, Schuetz EG, Thummel KE. Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells. Biochemical Pharmacology. 84: 391-401. PMID 22562045 DOI: 10.1016/J.Bcp.2012.04.019 |
0.597 |
|
| 2012 |
Dickmann LJ, VandenBrink BM, Lin YS. In vitro hepatotoxicity and cytochrome P450 induction and inhibition characteristics of carnosic acid, a dietary supplement with antiadipogenic properties. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1263-7. PMID 22531045 DOI: 10.1124/Dmd.112.044909 |
0.383 |
|
| 2012 |
Wang Z, Lin YS, Zheng XE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE. An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway. Molecular Pharmacology. 81: 498-509. PMID 22205755 DOI: 10.1124/Mol.111.076356 |
0.62 |
|
| 2011 |
Wang Z, Senn T, Kalhorn T, Zheng XE, Zheng S, Davis CL, Hebert MF, Lin YS, Thummel KE. Simultaneous measurement of plasma vitamin D(3) metabolites, including 4β,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometry. Analytical Biochemistry. 418: 126-33. PMID 21784054 DOI: 10.1016/J.Ab.2011.06.043 |
0.545 |
|
| 2011 |
Innocenti F, Cooper GM, Stanaway IB, Gamazon ER, Smith JD, Mirkov S, Ramirez J, Liu W, Lin YS, Moloney C, Aldred SF, Trinklein ND, Schuetz E, Nickerson DA, Thummel KE, et al. Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. Plos Genetics. 7: e1002078. PMID 21637794 DOI: 10.1371/Journal.Pgen.1002078 |
0.584 |
|
| 2010 |
Zhou L, Naraharisetti SB, Liu L, Wang H, Lin YS, Isoherranen N, Unadkat JD, Hebert MF, Mao Q. Contributions of human cytochrome P450 enzymes to glyburide metabolism. Biopharmaceutics & Drug Disposition. 31: 228-42. PMID 20437462 DOI: 10.1002/Bdd.706 |
0.49 |
|
| 2010 |
Suresh BN, Lin YS, Rieder MJ, Marciante KD, Psaty BM, Thummel KE, Totah RA. Human liver expression of CYP2C8: Gender, age, and genotype effects Drug Metabolism and Disposition. 38: 889-893. PMID 20190184 DOI: 10.1124/Dmd.109.031542 |
0.644 |
|
| 2009 |
McConn DJ, Lin YS, Mathisen TL, Blough DK, Xu Y, Hashizume T, Taylor SL, Thummel KE, Shuhart MC. Reduced duodenal cytochrome P450 3A protein expression and catalytic activity in patients with cirrhosis. Clinical Pharmacology and Therapeutics. 85: 387-93. PMID 19212316 DOI: 10.1038/Clpt.2008.292 |
0.774 |
|
| 2007 |
Shao J, Stapleton PL, Lin YS, Gallagher EP. Cytochrome p450 and glutathione s-transferase mRNA expression in human fetal liver hematopoietic stem cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 168-75. PMID 17050647 DOI: 10.1124/Dmd.106.012757 |
0.435 |
|
| 2006 |
Lamba J, Strom S, Venkataramanan R, Thummel KE, Lin YS, Liu W, Cheng C, Lamba V, Watkins PB, Schuetz E. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype. Clinical Pharmacology and Therapeutics. 79: 325-38. PMID 16580901 DOI: 10.1016/J.Clpt.2005.11.013 |
0.586 |
|
| 2004 |
Dai Y, Iwanaga K, Lin YS, Hebert MF, Davis CL, Huang W, Kharasch ED, Thummel KE. In vitro metabolism of cyclosporine A by human kidney CYP3A5 Biochemical Pharmacology. 68: 1889-1902. PMID 15450954 DOI: 10.1016/J.Bcp.2004.07.012 |
0.779 |
|
| 2004 |
Huang W, Lin YS, McConn DJ, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE. Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1434-45. PMID 15383492 DOI: 10.1124/Dmd.104.001313 |
0.746 |
|
| 2004 |
McConn DJ, Lin YS, Allen K, Kunze KL, Thummel KE. Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1083-91. PMID 15377640 DOI: 10.1124/Dmd.32.10.1083 |
0.768 |
|
| 2004 |
Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E. Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. The Journal of Pharmacology and Experimental Therapeutics. 311: 811-21. PMID 15194709 DOI: 10.1124/Jpet.104.069310 |
0.351 |
|
| 2003 |
Hebert MF, Dowling AL, Gierwatowski C, Lin YS, Edwards KL, Davis CL, Marsh CL, Schuetz EG, Thummel KE. Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors. Pharmacogenetics. 13: 661-74. PMID 14583679 DOI: 10.1097/00008571-200311000-00002 |
0.556 |
|
| 2003 |
Park JM, Lin YS, Calamia JC, Thummel KE, Slattery JT, Kalhorn TF, Carithers RL, Levy AE, Marsh CL, Hebert MF. Transiently altered acetaminophen metabolism after liver transplantation. Clinical Pharmacology and Therapeutics. 73: 545-53. PMID 12811364 DOI: 10.1016/S0009-9236(03)00062-6 |
0.602 |
|
| 2003 |
Givens RC, Lin YS, Dowling AL, Thummel KE, Lamba JK, Schuetz EG, Stewart PW, Watkins PB. CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1297-300. PMID 12754175 DOI: 10.1152/Japplphysiol.00322.2003 |
0.591 |
|
| 2003 |
Rettie AE, Tai G, Veenstra DL, Farin FM, Srinouanprachan S, Lin YS, Thummel KE, Hines RN. CYP2C9 exon 4 mutations and warfarin dose phenotype in Asians. Blood. 101: 2896-7. PMID 12642346 DOI: 10.1182/Blood-2002-11-3452 |
0.496 |
|
| 2002 |
Lamba JK, Lin YS, Schuetz EG, Thummel KE. Genetic contribution to variable human CYP3A-mediated metabolism. Advanced Drug Delivery Reviews. 54: 1271-94. PMID 12406645 DOI: 10.1016/S0169-409X(02)00066-2 |
0.662 |
|
| 2002 |
Lin YS, Dowling AL, Quigley SD, Farin FM, Zhang J, Lamba J, Schuetz EG, Thummel KE. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Molecular Pharmacology. 62: 162-72. PMID 12065767 DOI: 10.1124/Mol.62.1.162 |
0.648 |
|
| 2002 |
Lamba JK, Lin YS, Thummel K, Daly A, Watkins PB, Strom S, Zhang J, Schuetz EG. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics. 12: 121-32. PMID 11875366 DOI: 10.1097/00008571-200203000-00006 |
0.626 |
|
| 2001 |
Lin YS, Lockwood GF, Graham MA, Brian WR, Loi CM, Dobrinska MR, Shen DD, Watkins PB, Wilkinson GR, Kharasch ED, Thummel KE. In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration. Pharmacogenetics. 11: 781-91. PMID 11740342 DOI: 10.1097/00008571-200112000-00006 |
0.574 |
|
| 2001 |
Thummel KE, Brimer C, Yasuda K, Thottassery J, Senn T, Lin Y, Ishizuka H, Kharasch E, Schuetz J, Schuetz E. Transcriptional control of intestinal cytochrome P-4503A by 1α,25-dihydroxy vitamin D3 Molecular Pharmacology. 60: 1399-1406. PMID 11723248 DOI: 10.1124/Mol.60.6.1399 |
0.583 |
|
| 2001 |
Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature Genetics. 27: 383-91. PMID 11279519 DOI: 10.1038/86882 |
0.661 |
|
| Show low-probability matches. |