Year |
Citation |
Score |
2020 |
Giménez-Llort L, Santana-Santana M, Bayascas JR. The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice. Frontiers in Behavioral Neuroscience. 14: 61. PMID 32457586 DOI: 10.3389/Fnbeh.2020.00061 |
0.31 |
|
2020 |
Alcaraz E, Vilardell J, Borgo C, Sarró E, Plana M, Marin O, Pinna LA, Bayascas JR, Meseguer A, Salvi M, Itarte E, Ruzzene M. Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells. Plos One. 15: e0227340. PMID 31910234 DOI: 10.1371/Journal.Pone.0227340 |
0.399 |
|
2017 |
Yang S, Pascual-Guiral S, Ponce R, Giménez-Llort L, Baltrons MA, Arancio O, Palacio JR, Clos VM, Yuste VJ, Bayascas JR. Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides. Frontiers in Aging Neuroscience. 9: 435. PMID 29358916 DOI: 10.3389/Fnagi.2017.00435 |
0.356 |
|
2016 |
Cordón-Barris L, Pascual-Guiral S, Yang S, Giménez-Llort L, Lope-Piedrafita S, Niemeyer C, Claro E, Lizcano JM, Bayascas JR. Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors. Molecular and Cellular Biology. 36: 2967-2982. PMID 27644329 DOI: 10.1128/Mcb.00230-16 |
0.422 |
|
2016 |
Soriano A, París-Coderch L, Jubierre L, Martínez A, Zhou X, Piskareva O, Bray I, Vidal I, Almazán-Moga A, Molist C, Roma J, Bayascas JR, Casanovas O, Stallings RL, Sánchez de Toledo J, et al. MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes. Oncotarget. 7: 9271-87. PMID 26824183 DOI: 10.18632/Oncotarget.7005 |
0.322 |
|
2014 |
Zhou X, Cordon-Barris L, Zurashvili T, Bayascas JR. Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses. Cell Cycle. 13: 3164-3168. PMID 25485494 DOI: 10.4161/15384101.2014.962954 |
0.371 |
|
2013 |
Erazo T, Moreno A, Ruiz-Babot G, Rodríguez-Asiain A, Morrice NA, Espadamala J, Bayascas JR, Gómez N, Lizcano JM. Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex. Molecular and Cellular Biology. 33: 1671-86. PMID 23428871 DOI: 10.1128/Mcb.01246-12 |
0.421 |
|
2013 |
Zurashvili T, Cordón-Barris L, Ruiz-Babot G, Zhou X, Lizcano JM, Gómez N, Giménez-Llort L, Bayascas JR. Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. Molecular and Cellular Biology. 33: 1027-40. PMID 23275438 DOI: 10.1128/Mcb.01052-12 |
0.414 |
|
2011 |
Rodríguez-Asiain A, Ruiz-Babot G, Romero W, Cubí R, Erazo T, Biondi RM, Bayascas JR, Aguilera J, Gómez N, Gil C, Claro E, Lizcano JM. Brain specific kinase-1 BRSK1/SAD-B associates with lipid rafts: modulation of kinase activity by lipid environment. Biochimica Et Biophysica Acta. 1811: 1124-35. PMID 22020259 DOI: 10.1016/J.Bbalip.2011.10.004 |
0.358 |
|
2010 |
Bayascas JR. PDK1: The Major Transducer of PI 3-Kinase Actions Current Topics in Microbiology and Immunology. 346: 9-29. PMID 20563709 DOI: 10.1007/82_2010_43 |
0.409 |
|
2010 |
Sanchez Canedo C, Demeulder B, Ginion A, Bayascas JR, Balligand JL, Alessi DR, Vanoverschelde JL, Beauloye C, Hue L, Bertrand L. Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation. American Journal of Physiology. Endocrinology and Metabolism. 298: E761-9. PMID 20051528 DOI: 10.1152/Ajpendo.00421.2009 |
0.566 |
|
2009 |
Waugh C, Sinclair L, Finlay D, Bayascas JR, Cantrell D. Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation. Molecular and Cellular Biology. 29: 5952-62. PMID 19703999 DOI: 10.1128/Mcb.00585-09 |
0.365 |
|
2008 |
Bayascas JR. Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways. Cell Cycle (Georgetown, Tex.). 7: 2978-82. PMID 18802401 DOI: 10.4161/Cc.7.19.6810 |
0.409 |
|
2008 |
Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, et al. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Molecular and Cellular Biology. 28: 3258-72. PMID 18347057 DOI: 10.1128/Mcb.02032-07 |
0.586 |
|
2007 |
Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX. The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11228-41. PMID 17942717 DOI: 10.1523/Jneurosci.3462-07.2007 |
0.361 |
|
2006 |
Bayascas JR, Sakamoto K, Armit L, Arthur JS, Alessi DR. Evaluation of approaches to generation of tissue-specific knock-in mice. The Journal of Biological Chemistry. 281: 28772-81. PMID 16887794 DOI: 10.1074/Jbc.M606789200 |
0.54 |
|
2006 |
Alessi DR, Sakamoto K, Bayascas JR. LKB1-dependent signaling pathways Annual Review of Biochemistry. 75: 137-163. PMID 16756488 DOI: 10.1146/Annurev.Biochem.75.103004.142702 |
0.568 |
|
2005 |
Bayascas JR, Leslie NR, Parsons R, Fleming S, Alessi DR. Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice. Current Biology : Cb. 15: 1839-46. PMID 16243031 DOI: 10.1016/J.Cub.2005.08.066 |
0.58 |
|
2005 |
Yuste VJ, Sánchez-López I, Solé C, Moubarak RS, Bayascas JR, Dolcet X, Encinas M, Susin SA, Comella JX. The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. The Journal of Biological Chemistry. 280: 35670-83. PMID 16049016 DOI: 10.1074/Jbc.M504015200 |
0.301 |
|
2005 |
Bayascas JR, Alessi DR. Regulation of Akt/PKB Ser473 phosphorylation Molecular Cell. 18: 143-145. PMID 15837416 DOI: 10.1016/J.Molcel.2005.03.020 |
0.534 |
|
2004 |
Sole C, Dolcet X, Segura MF, Gutierrez H, Diaz-Meco MT, Gozzelino R, Sanchis D, Bayascas JR, Gallego C, Moscat J, Davies AM, Comella JX. The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling. The Journal of Cell Biology. 167: 479-92. PMID 15520226 DOI: 10.1083/Jcb.200403093 |
0.354 |
|
2004 |
Bayascas JR, Yuste VJ, Solé C, Sánchez-López I, Segura MF, Perera R, Comella JX. Characterization of splice variants of human caspase-activated DNase with CIDE-N structure and function. Febs Letters. 566: 234-40. PMID 15147901 DOI: 10.1016/J.Febslet.2004.04.050 |
0.365 |
|
2002 |
Bayascas JR, Yuste VJ, Benito E, Garcia-Fernàndez J, Comella JX. Isolation of AmphiCASP-3/7, an ancestral caspase from amphioxus (Branchiostoma floridae). Evolutionary considerations for vertebrate caspases. Cell Death and Differentiation. 9: 1078-89. PMID 12232796 DOI: 10.1038/Sj.Cdd.4401075 |
0.591 |
|
2002 |
Yuste VJ, Sánchez-López I, Solé C, Encinas M, Bayascas JR, Boix J, Comella JX. The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells. Journal of Neurochemistry. 80: 126-39. PMID 11796751 DOI: 10.1046/J.0022-3042.2001.00695.X |
0.336 |
|
2001 |
Yuste VJ, Bayascas JR, Llecha N, Sánchez-López I, Boix J, Comella JX. The Absence of Oligonucleosomal DNA Fragmentation during Apoptosis of IMR-5 Neuroblastoma Cells DISAPPEARANCE OF THE CASPASE-ACTIVATED DNase Journal of Biological Chemistry. 276: 22323-22331. PMID 11294834 DOI: 10.1074/Jbc.M100072200 |
0.344 |
|
2001 |
Saló E, Tauler J, Jimenez E, Bayascas JR, Gonzalez-Linares J, Garcia-Fernàndez J, Baguñà J. Hox and ParaHox Genes in Flatworms: Characterization and Expression Integrative and Comparative Biology. 41: 652-663. DOI: 10.1668/0003-1569(2001)041[0652:Hapgif]2.0.Co;2 |
0.644 |
|
1999 |
Soler RM, Dolcet X, Encinas M, Egea J, Bayascas JR, Comella JX. Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons. The Journal of Neuroscience. 19: 9160-9169. DOI: 10.1523/Jneurosci.19-21-09160.1999 |
0.393 |
|
1998 |
Bayascas JR, Castillo E, Saló E. Platyhelminthes have a Hox code differentially activated during regeneration, with genes closely related to those of spiralian protostomes Development Genes and Evolution. 208: 467-473. PMID 9799427 DOI: 10.1007/S004270050204 |
0.409 |
|
1998 |
Bayascas JR, Castillo E, Muñoz-Mármol AM, Baguñà J, Saló E. Synchronous and early activation of planarian Hox genes and the re-specification of body axes during regeneration in Dugesia (G.) tigrina (Turbellaria; Tricladida) Hydrobiologia. 383: 125-130. DOI: 10.1023/A:1003427408356 |
0.621 |
|
1997 |
Muñoz-Mármol AM, Bayascas JR, Castillo E, Casali A, Saló E. Planarian homeobox gene Dtprd-1 is expressed in specific gland cells and belongs to a new family within the paired-like class. Development Genes and Evolution. 207: 296-305. PMID 27747427 DOI: 10.1007/S004270050117 |
0.405 |
|
1997 |
Bueno D, Castillo E, Vispo M, Cebrià F, Bayascas JR, Saló E, Romero R. New protocol to visualize gene expression in intact and regenerating adult planarians by whole-mount in situhybridization Technical Tips Online. 2: 164-166. DOI: 10.1016/S1366-2120(08)70073-4 |
0.31 |
|
1996 |
Bayascas JR, Castillo E, Munoz-Marmol A, Salo E. Hox genes disobey colinearity and do not distinguish head from tail during planarian regeneration. The International Journal of Developmental Biology. 40. DOI: 10.1387/Ijdb.9087748 |
0.384 |
|
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