| Year |
Citation |
Score |
| 2024 |
Hague WB, Williamson C, Beuers U. Intrahepatic cholestasis of pregnancy: Introduction and overview 2024. Obstetric Medicine. 17: 138-143. PMID 39262909 DOI: 10.1177/1753495X241265772 |
0.373 |
|
| 2024 |
Amarsi R, Furse S, Cleaton MAM, Maurel S, Mitchell AL, Ferguson-Smith AC, Cenac N, Williamson C, Koulman A, Charalambous M. A co-ordinated transcriptional programme in the maternal liver supplies long chain polyunsaturated fatty acids to the conceptus using phospholipids. Nature Communications. 15: 6767. PMID 39117683 DOI: 10.1038/s41467-024-51089-z |
0.4 |
|
| 2022 |
Borges Manna L, Williamson C. Nuclear Receptors in Pregnancy and Outcomes: Clinical Perspective. Advances in Experimental Medicine and Biology. 1390: 3-19. PMID 36107310 DOI: 10.1007/978-3-031-11836-4_1 |
0.317 |
|
| 2022 |
Dixon PH, Levine AP, Cebola I, Chan MMY, Amin AS, Aich A, Mozere M, Maude H, Mitchell AL, Zhang J, Chambers J, Syngelaki A, Donnelly J, Cooley S, Geary M, ... ... Williamson C, et al. GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements. Nature Communications. 13: 4840. PMID 35977952 DOI: 10.1038/s41467-022-29931-z |
0.311 |
|
| 2022 |
Terrault NA, Williamson C. Pregnancy-Associated Liver Diseases. Gastroenterology. PMID 35276220 DOI: 10.1053/j.gastro.2022.01.060 |
0.338 |
|
| 2021 |
Yang X, Zhang C, Williamson C, Liu Y, Zhou Y, Liu C, Chen L, Zhang Y, Korevaar T, Wu W, Fan J. Association of Maternal Thyroid Function with Gestational Hypercholanemia. Thyroid : Official Journal of the American Thyroid Association. PMID 34941431 DOI: 10.1089/thy.2021.0242 |
0.36 |
|
| 2021 |
Ovadia C, Williamson C. Intrahepatic cholestasis of pregnancy: are we expecting too much from ursodeoxycholic acid? - Authors' reply. The Lancet. Gastroenterology & Hepatology. 6: 886-887. PMID 34626560 DOI: 10.1016/S2468-1253(21)00304-6 |
0.42 |
|
| 2021 |
Markus C, Coat S, Marschall HU, Williamson C, Dixon P, Fuller M, Matthews S, Rankin W, Metz M, Hague WM. The BACH project protocol: an international multicentre total Bile Acid Comparison and Harmonisation project and sub-study of the TURRIFIC randomised trial. Clinical Chemistry and Laboratory Medicine. PMID 34355544 DOI: 10.1515/cclm-2021-0496 |
0.311 |
|
| 2021 |
Ovadia C, Sajous J, Seed PT, Patel K, Williamson NJ, Attilakos G, Azzaroli F, Bacq Y, Batsry L, Broom K, Brun-Furrer R, Bull L, Chambers J, Cui Y, Ding M, ... ... Williamson C, et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. The Lancet. Gastroenterology & Hepatology. PMID 33915090 DOI: 10.1016/S2468-1253(21)00074-1 |
0.377 |
|
| 2021 |
Manna LB, Williamson C. Nuclear receptors, gestational metabolism and maternal metabolic disorders. Molecular Aspects of Medicine. 100941. PMID 33455843 DOI: 10.1016/j.mam.2021.100941 |
0.309 |
|
| 2021 |
Hague WM, Callaway L, Chambers J, Chappell L, Coat S, de Haan-Jebbink J, Dekker M, Dixon P, Dodd J, Fuller M, Gordijn S, Graham D, Heikinheimo O, Hennessy A, Kaaja R, ... ... Williamson C, et al. A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy: the TURRIFIC randomised trial. Bmc Pregnancy and Childbirth. 21: 51. PMID 33435904 DOI: 10.1186/s12884-020-03481-y |
0.332 |
|
| 2020 |
Fan HM, Mitchell AL, Williamson C. ENDOCRINOLOGY IN PREGNANCY: Metabolic impact of bile acids in gestation. European Journal of Endocrinology. PMID 33434155 DOI: 10.1530/EJE-20-1101 |
0.424 |
|
| 2020 |
Conti-Ramsden F, McEwan M, Hill R, Wade J, Abraham G, Buckeldee O, Williamson C, Knight CL, Girling J, Chappell LC. Detection of additional abnormalities or co-morbidities in women with suspected intrahepatic cholestasis of pregnancy. Obstetric Medicine. 13: 185-191. PMID 33343695 DOI: 10.1177/1753495X19868873 |
0.415 |
|
| 2020 |
Vasavan T, Deepak S, Jayawardane IA, Lucchini M, Martin C, Geenes V, Yang J, Lövgren-Sandblom A, Seed PT, Chambers J, Stone S, Kurlak L, Dixon PH, Marschall HU, Gorelik J, ... ... Williamson C, et al. Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations. Journal of Hepatology. PMID 33276032 DOI: 10.1016/j.jhep.2020.11.038 |
0.779 |
|
| 2020 |
Rahim MN, Pirani T, Williamson C, Heneghan MA. Management of pregnancy in women with cirrhosis. United European Gastroenterology Journal. 2050640620977034. PMID 33259738 DOI: 10.1177/2050640620977034 |
0.33 |
|
| 2020 |
Ferraro E, Pozhidaeva L, Pitcher DS, Mansfield C, Koh JHB, Williamson C, Aslanidi O, Gorelik J, Ng FS. Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts. Scientific Reports. 10: 15284. PMID 32943714 DOI: 10.1038/S41598-020-72016-4 |
0.702 |
|
| 2020 |
Bellafante E, McIlvride S, Nikolova V, Fan HM, Manna LB, Chambers J, Machirori M, Banerjee A, Murphy K, Martineau M, Schoonjans K, Marschall HU, Jones P, Williamson C. Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis. Scientific Reports. 10: 11523. PMID 32661285 DOI: 10.1038/S41598-020-67968-6 |
0.407 |
|
| 2020 |
Pataia V, McIlvride S, Papacleovoulou G, Ovadia C, McDonald JAK, Wahlström A, Jansen E, Adorini L, Shapiro D, Marchesi JR, Marschall HU, Williamson C. Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32597707 DOI: 10.1152/Ajpgi.00126.2020 |
0.541 |
|
| 2020 |
Borges Manna L, Papacleovoulou G, Flaviani F, Pataia V, Qadri A, Abu-Hayyeh S, McIlvride S, Jansen E, Dixon P, Chambers J, Vazquez-Lopez M, Wahlström A, Kitaba N, Marschall HU, Godfrey KM, ... ... Williamson C, et al. Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy. Scientific Reports. 10: 10361. PMID 32587408 DOI: 10.1038/S41598-020-67301-1 |
0.514 |
|
| 2020 |
Rahim MN, Williamson C, Kametas NA, Heneghan MA. Using pregnancy to assess risk and predict women's health. Eclinicalmedicine. 20: 100292. PMID 32211598 DOI: 10.1016/J.Eclinm.2020.100292 |
0.325 |
|
| 2020 |
Chappell LC, Williamson C, Thornton JG. Ursodeoxycholic acid for adverse perinatal outcomes - Authors' reply. Lancet (London, England). 395: 780-781. PMID 32145786 DOI: 10.1016/S0140-6736(19)32970-8 |
0.378 |
|
| 2020 |
Ovadia C, Perdones-Montero A, Fan HM, Mullish BH, McDonald JAK, Papacleovoulou G, Wahlström A, Ståhlman M, Tsakmaki A, Clarke LCD, Sklavounos A, Dixon PH, Bewick GA, Walters JRF, Marschall HU, ... ... Williamson C, et al. Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy. Scientific Reports. 10: 3895. PMID 32127609 DOI: 10.1038/S41598-020-60821-W |
0.499 |
|
| 2020 |
Cauldwell M, Mackie FL, Steer PJ, Henehghan MA, Baalman JH, Brennand J, Johnston T, Dockree S, Hedley C, Jarvis S, Khan S, McAuliffe FM, Mackillop L, Penna L, Smith B, ... ... Williamson C, et al. Pregnancy outcomes in women with primary biliary cholangitis and primary sclerosing cholangitis: A retrospective cohort study. Bjog : An International Journal of Obstetrics and Gynaecology. PMID 32012415 DOI: 10.1111/1471-0528.16119 |
0.366 |
|
| 2020 |
Rahim MN, Long L, Penna L, Williamson C, Kametas NA, Nicolaides KH, Heneghan MA. Pregnancy in liver transplantation. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 31950556 DOI: 10.1002/Lt.25717 |
0.414 |
|
| 2019 |
Borges Manna L, Ovadia C, Lövgren-Sandblom A, Chambers J, Begum S, Seed P, Walker I, Chappell LC, Marschall HU, Williamson C. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study. Bjog : An International Journal of Obstetrics and Gynaecology. PMID 31483939 DOI: 10.1111/1471-0528.15926 |
0.501 |
|
| 2019 |
Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, Chambers J, Hunter R, Dorling J, Williamson C, Thornton JG. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet (London, England). PMID 31378395 DOI: 10.1016/S0140-6736(19)31270-X |
0.528 |
|
| 2019 |
McIlvride S, Nikolova V, Fan HM, McDonald JAK, Wahlström A, Bellafante E, Jansen E, Adorini L, Shapiro D, Jones P, Marchesi JR, Marschall HU, Williamson C. Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in a mouse model of gestational diabetes. American Journal of Physiology. Endocrinology and Metabolism. PMID 31237448 DOI: 10.1152/Ajpendo.00407.2018 |
0.417 |
|
| 2019 |
Ovadia C, Perdones-Montero A, Spagou K, Smith A, Sarafian MH, Gomez Romero M, Bellafante E, Clarke LC, Sadiq F, Nikolova V, Mitchell A, Dixon PH, Santa-Pinter N, Wahlström A, Abu-Hayyeh S, ... ... Williamson C, et al. Enhanced microbial bile acid deconjugation and impaired ileal uptake in pregnancy repress intestinal regulation of bile acid synthesis. Hepatology (Baltimore, Md.). PMID 30983011 DOI: 10.1002/Hep.30661 |
0.543 |
|
| 2019 |
Ovadia C, Seed PT, Sklavounos A, Geenes V, Di Illio C, Chambers J, Kohari K, Bacq Y, Bozkurt N, Brun-Furrer R, Bull L, Estiú MC, Grymowicz M, Gunaydin B, Hague WM, ... ... Williamson C, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. Lancet (London, England). PMID 30773280 DOI: 10.1016/S0140-6736(18)31877-4 |
0.488 |
|
| 2018 |
Chappell LC, Chambers J, Dixon PH, Dorling J, Hunter R, Bell JL, Bowler U, Hardy P, Juszczak E, Linsell L, Rounding C, Smith A, Williamson C, Thornton JG. Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES). Trials. 19: 657. PMID 30482254 DOI: 10.1186/S13063-018-3018-4 |
0.51 |
|
| 2018 |
Hagström H, Höijer J, Marschall HU, Williamson C, Heneghan MA, Westbrook RH, Ludvigsson JF, Stephansson O. Outcomes of Pregnancy in Mothers With Cirrhosis: A National Population-Based Cohort Study of 1.3 Million Pregnancies. Hepatology Communications. 2: 1299-1305. PMID 30411076 DOI: 10.1002/hep4.1255 |
0.328 |
|
| 2018 |
Ovadia C, Lövgren-Sandblom A, Edwards LA, Langedijk J, Geenes V, Chambers J, Cheng F, Clarke L, Begum S, Noori M, Pusey C, Padmagirison R, Agarwal S, Peerless J, Cheesman K, ... ... Williamson C, et al. Therapeutic plasma exchange as a novel treatment for severe intrahepatic cholestasis of pregnancy: Case series and mechanism of action. Journal of Clinical Apheresis. PMID 30321466 DOI: 10.1002/Jca.21654 |
0.474 |
|
| 2018 |
Pataia V, Papacleovoulou G, Nikolova V, Samuelsson AM, Chambers S, Jansen E, Taylor PD, Poston L, Williamson C. Paternal cholestasis exacerbates obesity-associated hypertension in male offspring but is prevented by paternal ursodeoxycholic acid treatment. International Journal of Obesity (2005). PMID 29795465 DOI: 10.1038/S41366-018-0095-0 |
0.319 |
|
| 2018 |
Ibrahim E, Diakonov I, Arunthavarajah D, Swift T, Goodwin M, McIlvride S, Nikolova V, Williamson C, Gorelik J. Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5. Scientific Reports. 8: 7110. PMID 29740092 DOI: 10.1038/S41598-018-25569-4 |
0.788 |
|
| 2018 |
Harrington P, Nelson-Piercy C, Williamson C, Cooper N, Kesse-Adu R, Robinson S. Refractory severe immune thrombocytopenia in a twin pregnancy. Obstetric Medicine. 11: 35-38. PMID 29636813 DOI: 10.1177/1753495X17709188 |
0.362 |
|
| 2018 |
Ovadia C, Marschall HU, Williamson C. The importance of gestation-adjusted birthweight centile in assessment of fetal growth in metabolic conditions. Journal of Clinical Research in Pediatric Endocrinology. PMID 29537381 DOI: 10.4274/Jcrpe.5308 |
0.322 |
|
| 2018 |
Chappell LC, Chambers J, Thornton JG, Williamson C. Does ursodeoxycholic acid improve perinatal outcomes in women with intrahepatic cholestasis of pregnancy? Bmj (Clinical Research Ed.). 360: k104. PMID 29419378 DOI: 10.1136/Bmj.K104 |
0.513 |
|
| 2018 |
Vasavan T, Ferraro E, Ibrahim E, Dixon P, Gorelik J, Williamson C. Heart and bile acids - Clinical consequences of altered bile acid metabolism. Biochimica Et Biophysica Acta. PMID 29317337 DOI: 10.1016/J.Bbadis.2017.12.039 |
0.806 |
|
| 2018 |
Hagström H, Höijer J, Marschall H-, Williamson C, Heneghan M, Westbrook R, Ludvigsson JF, Stephansson O. Outcomes of pregnancy in women with cirrhosis – a national, population-based cohort study Journal of Hepatology. 68. DOI: 10.1016/S0168-8278(18)31649-0 |
0.36 |
|
| 2018 |
Vasavan T, Martin C, Jayawardane I, Deepak S, Geenes V, Lucchini M, Chambers J, Kurlak L, Thornton J, Broughton-Pipkin F, Hayes-Gill B, Fifer W, Williamson C. The PR interval in the fetal electrocardiogram is significantly prolonged in severe intrahepatic cholestasis of pregnancy and potentially normalised by UDCA therapy Journal of Hepatology. 68: S624-S625. DOI: 10.1016/S0168-8278(18)31505-8 |
0.417 |
|
| 2018 |
Pataia V, Papacleovoulou G, Jansen E, Adorini L, Marschall H-, Williamson C. Obeticholic acid improves fetal hypercholanaemia during cholestatic gestation Journal of Hepatology. 68. DOI: 10.1016/S0168-8278(18)31061-4 |
0.507 |
|
| 2018 |
Dixon P, Nye L, Langer J, Nikolaenko V, Williamson C, Want E. 59. UDCA treatment partially reverses placental dyslipidemia in intrahepatic cholestasis of pregnancy Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13. DOI: 10.1016/J.Preghy.2018.08.191 |
0.418 |
|
| 2018 |
Chappell L, Hill R, Conti-Ramsden F, Wade J, Williamson C. 419. Detection of additional abnormalities or co-morbidities in women with intrahepatic cholestasis of pregnancy Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13. DOI: 10.1016/J.Preghy.2018.08.146 |
0.425 |
|
| 2018 |
Chappell L, Ovadia C, Seed P, Sklavounos A, Thornton J, Williamson C. 273. Adverse perinatal outcomes of intrahepatic cholestasis of pregnancy and association with biochemical markers: Results of aggregate and independent patient data meta-analyses Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13. DOI: 10.1016/J.Preghy.2018.08.111 |
0.484 |
|
| 2017 |
Adeyemi O, Alvarez-Laviada A, Schultz F, Ibrahim E, Trauner M, Williamson C, Glukhov AV, Gorelik J. Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis. Plos One. 12: e0183167. PMID 28934223 DOI: 10.1371/Journal.Pone.0183167 |
0.766 |
|
| 2017 |
McIlvride S, Mushtaq A, Papacleovoulou G, Hurling C, Steel J, Jansen E, Abu-Hayyeh S, Williamson C. A progesterone-brown fat axis is involved in regulating fetal growth. Scientific Reports. 7: 10671. PMID 28878263 DOI: 10.1038/S41598-017-10979-7 |
0.426 |
|
| 2017 |
Quartermaine G, Lambert K, Rees K, Seed PT, Dhanjal MK, Knight M, McCance DR, Williamson C. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome; a UKOSS study with case control comparisons. Bjog : An International Journal of Obstetrics and Gynaecology. PMID 28872770 DOI: 10.1111/1471-0528.14918 |
0.373 |
|
| 2017 |
Alawi KM, Tandio D, Xu J, Thakore P, Papacleovoulou G, Fernandes ES, Legido-Quigley C, Williamson C, Brain SD. Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis. Scientific Reports. 7: 2338. PMID 28539583 DOI: 10.1038/S41598-017-02439-Z |
0.325 |
|
| 2017 |
Lim TY, Coltart I, Foskett P, Thompson R, Strautnieks S, Penna L, Williamson C, Miquel R, Heneghan MA. Donor transmitted mutation of the ABCB11 gene and ensuing intra-hepatic cholestasis of pregnancy in a liver transplant recipient. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 28524363 DOI: 10.1002/Lt.24776 |
0.403 |
|
| 2017 |
McIlvride S, Dixon PH, Williamson C. Bile acids and gestation. Molecular Aspects of Medicine. PMID 28506676 DOI: 10.1016/J.Mam.2017.05.003 |
0.516 |
|
| 2017 |
Pataia V, Dixon PH, Williamson C. Pregnancy and bile acid disorders. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00028.2017. PMID 28450276 DOI: 10.1152/Ajpgi.00028.2017 |
0.498 |
|
| 2017 |
Estiú MC, Frailuna MA, Otero C, Dericco M, Williamson C, Marin JJG, Macias RIR. Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid. Plos One. 12: e0176504. PMID 28437442 DOI: 10.1371/Journal.Pone.0176504 |
0.427 |
|
| 2017 |
Nikolova V, Papacleovoulou G, Bellafante E, Borges Manna L, Jansen E, Baron S, Abu-Hayyeh S, Parker MG, Williamson C. Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00449.2016. PMID 28420650 DOI: 10.1152/Ajpendo.00449.2016 |
0.467 |
|
| 2017 |
Papacleovoulou G, Nikolova V, Oduwole O, Chambers J, Vazquez-Lopez M, Jansen E, Nicolaides K, Parker M, Williamson C. Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28082353 DOI: 10.1096/Fj.201601032R |
0.417 |
|
| 2016 |
Lambert K, Rees K, Seed PT, Dhanjal MK, Knight M, McCance DR, Williamson C. Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes. Obstetrics and Gynecology. PMID 27926659 DOI: 10.1097/Aog.0000000000001747 |
0.365 |
|
| 2016 |
Jayasena CN, Abbara A, Comninos AN, Narayanaswamy S, Gonzalez Maffe J, Izzi-Engbeaya C, Oldham J, Lee TT, Sarang Z, Malik Z, Dhanjal MK, Williamson C, Regan L, Bloom SR, Dhillo WS. Novel circulating placental markers prokineticin-1, soluble fms-like tyrosine kinase-1, soluble endoglin and placental growth factor and association with late miscarriage. Human Reproduction (Oxford, England). PMID 27664209 DOI: 10.1093/Humrep/Dew225 |
0.311 |
|
| 2016 |
Ovadia C, Williamson C. Intrahepatic cholestasis of pregnancy: Recent advances. Clinics in Dermatology. 34: 327-34. PMID 27265070 DOI: 10.1016/J.Clindermatol.2016.02.004 |
0.472 |
|
| 2016 |
Johnston IM, Nolan JD, Pattni SS, Appleby RN, Zhang JH, Kennie SL, Madhan GK, Jameie-Oskooei S, Pathmasrirengam S, Lin J, Hong A, Dixon PH, Williamson C, Walters JR. Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea. The American Journal of Gastroenterology. PMID 26856750 DOI: 10.1038/Ajg.2015.424 |
0.384 |
|
| 2016 |
Dixon PH, Williamson C. The pathophysiology of intrahepatic cholestasis of pregnancy. Clinics and Research in Hepatology and Gastroenterology. PMID 26823041 DOI: 10.1016/J.Clinre.2015.12.008 |
0.485 |
|
| 2016 |
Schultz F, Hasan A, Alvarez-Laviada A, Miragoli M, Bhogal N, Wells S, Poulet C, Chambers J, Williamson C, Gorelik J. The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts. Progress in Biophysics and Molecular Biology. 120: 149-63. PMID 26777584 DOI: 10.1016/J.Pbiomolbio.2016.01.003 |
0.789 |
|
| 2016 |
Westbrook RH, Dusheiko G, Williamson C. Pregnancy and liver disease. Journal of Hepatology. 64: 933-45. PMID 26658682 DOI: 10.1016/J.Jhep.2015.11.030 |
0.437 |
|
| 2016 |
Wu L, Williamson C, Dixon P. Sa1569 Serum microRNA Analysis in Intrahepatic Cholestasis of Pregnancy Gastroenterology. 150: S1070. DOI: 10.1016/S0016-5085(16)33612-5 |
0.423 |
|
| 2016 |
Nolan JD, Appleby RN, Zhang JH, Kennie S, Williamson C, Walters JR. 615 Stimulation of Expression of Ileal Fibroblast Growth Factor 19 (FGF19) by Bile Acids Is Reduced in Patients With Crohn's Disease Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30529-7 |
0.315 |
|
| 2015 |
Abu-Hayyeh S, Ovadia C, Lieu T, Jensen DD, Chambers J, Dixon PH, Lövgren-Sandblom A, Bolier R, Tolenaars D, Kremer AE, Syngelaki A, Noori M, Williams D, Marin JJ, Monte MJ, ... ... Williamson C, et al. Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum. Hepatology (Baltimore, Md.). PMID 26426865 DOI: 10.1002/Hep.28265 |
0.436 |
|
| 2015 |
Abu-Hayyeh S, Williamson C. Progesterone metabolites as farnesoid X receptor inhibitors. Digestive Diseases (Basel, Switzerland). 33: 300-6. PMID 26045261 DOI: 10.1159/000371565 |
0.469 |
|
| 2015 |
Geenes V, Williamson C. Liver disease in pregnancy. Best Practice & Research. Clinical Obstetrics & Gynaecology. 29: 612-24. PMID 25982587 DOI: 10.1016/J.Mpmed.2015.08.010 |
0.422 |
|
| 2015 |
Geenes V, Chambers J, Khurana R, Shemer EW, Sia W, Mandair D, Elias E, Marschall HU, Hague W, Williamson C. Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 189: 59-63. PMID 25864112 DOI: 10.1016/J.Ejogrb.2015.03.020 |
0.46 |
|
| 2015 |
Martineau MG, Raker C, Dixon PH, Chambers J, Machirori M, King NM, Hooks ML, Manoharan R, Chen K, Powrie R, Williamson C. The metabolic profile of intrahepatic cholestasis of pregnancy is associated with impaired glucose tolerance, dyslipidemia, and increased fetal growth. Diabetes Care. 38: 243-8. PMID 25504029 DOI: 10.2337/Dc14-2143 |
0.417 |
|
| 2015 |
Kremer AE, Bolier R, Dixon PH, Geenes V, Chambers J, Tolenaars D, Ris-Stalpers C, Kaess BM, Rust C, van der Post JA, Williamson C, Beuers U, Oude Elferink RP. Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy. Journal of Hepatology. 62: 897-904. PMID 25450205 DOI: 10.1016/J.Jhep.2014.10.041 |
0.421 |
|
| 2015 |
Lee RH, Geenes VL, Williamson C. Primum non nocere: stillbirth rate in intrahepatic cholestasis of pregnancy. American Journal of Obstetrics and Gynecology. 212: 414. PMID 25434841 DOI: 10.1016/J.Ajog.2014.11.039 |
0.405 |
|
| 2015 |
Lawrance D, Williamson C, Boutelle MG, Cass AEG. Development of a disposable bile acid biosensor for use in the management of cholestasis Analytical Methods. 7: 3714-3719. DOI: 10.1039/C5Ay00372E |
0.438 |
|
| 2014 |
Jayasena CN, Abbara A, Izzi-Engbeaya C, Comninos AN, Harvey RA, Gonzalez Maffe J, Sarang Z, Ganiyu-Dada Z, Padilha AI, Dhanjal M, Williamson C, Regan L, Ghatei MA, Bloom SR, Dhillo WS. Reduced levels of plasma kisspeptin during the antenatal booking visit are associated with increased risk of miscarriage. The Journal of Clinical Endocrinology and Metabolism. 99: E2652-60. PMID 25127195 DOI: 10.1210/Jc.2014-1953 |
0.373 |
|
| 2014 |
Williamson C, Geenes V. Intrahepatic cholestasis of pregnancy. Obstetrics and Gynecology. 124: 120-133. PMID 24901263 DOI: 10.1016/J.Ogrm.2018.06.003 |
0.505 |
|
| 2014 |
Martineau M, Raker C, Powrie R, Williamson C. Authors' response: re: Intrahepatic cholestasis of pregnancy is not associated with stillbirth in an Australian maternity population. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 176: 205-6. PMID 24657183 DOI: 10.1016/J.Ejogrb.2014.03.001 |
0.4 |
|
| 2014 |
Martineau M, Raker C, Powrie R, Williamson C. Intrahepatic cholestasis of pregnancy is associated with an increased risk of gestational diabetes. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 176: 80-5. PMID 24462052 DOI: 10.1016/J.Ejogrb.2013.12.037 |
0.36 |
|
| 2014 |
Geenes V, Lövgren-Sandblom A, Benthin L, Lawrance D, Chambers J, Gurung V, Thornton J, Chappell L, Khan E, Dixon P, Marschall HU, Williamson C. The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid. Plos One. 9: e83828. PMID 24421907 DOI: 10.1371/Journal.Pone.0083828 |
0.547 |
|
| 2014 |
Herraez E, Lozano E, Poli E, Keitel V, De Luca D, Williamson C, Marin JJ, Macias RI. Role of macrophages in bile acid-induced inflammatory response of fetal lung during maternal cholestasis. Journal of Molecular Medicine (Berlin, Germany). 92: 359-72. PMID 24317353 DOI: 10.1007/S00109-013-1106-1 |
0.446 |
|
| 2014 |
Martineau M, Papacleovoulou G, Abu-Hayyeh S, Dixon PH, Ji H, Powrie R, Larson L, Chien EK, Williamson C. Cholestatic pregnancy is associated with reduced placental 11βHSD2 expression. Placenta. 35: 37-43. PMID 24262137 DOI: 10.1016/J.Placenta.2013.10.019 |
0.529 |
|
| 2014 |
Geenes V, Chappell LC, Seed PT, Steer PJ, Knight M, Williamson C. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study. Hepatology (Baltimore, Md.). 59: 1482-91. PMID 23857305 DOI: 10.1002/Hep.26617 |
0.458 |
|
| 2014 |
Norwood F, Dhanjal M, Hill M, James N, Jungbluth H, Kyle P, O'Sullivan G, Palace J, Robb S, Williamson C, Hilton-Jones D, Nelson-Piercy C. Myasthenia in pregnancy: best practice guidelines from a U.K. multispecialty working group. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 538-43. PMID 23757420 DOI: 10.1136/Jnnp-2013-305572 |
0.421 |
|
| 2014 |
Abu-Amero S, Thomas A, White S, Rogers K, Mir AMP, Solanky N, Leon L, Demetriou C, Ke X, Stanier S, Stanier B, Tzehaie HCMS, Al-Olabi L, Williamson C, Johnson M, et al. The Baby Bio Bank-A Legacy for Researchers Worldwide into Common Complications of Pregnancy Journal of General Practice. 2: 1-4. DOI: 10.4172/2329-9126.1000158 |
0.402 |
|
| 2014 |
Ovadia C, Abu-Hayyeh S, Dixon PH, Chambers J, Lövgren-Sandblom A, Bolier R, Tolenaars D, Beuers U, Oude-Elferink R, Jansen E, Seed PT, Marschall H-, Williamson C. P379 Biochemical Markers For Intrahepatic Cholestasis Of Pregnancy And Pruritus Gravidarum In Women With Gestational Pruritus Journal of Hepatology. 60. DOI: 10.1016/S0168-8278(14)60541-9 |
0.401 |
|
| 2013 |
Lambert K, Williamson C. Review of Presentation, Diagnosis and Management of Pituitary Tumours in Pregnancy. Obstetric Medicine. 6: 13-19. PMID 27757146 DOI: 10.1258/Om.2012.120022 |
0.348 |
|
| 2013 |
Frise C, Noori M, Williamson C. Severe metabolic alkalosis in pregnancy. Obstetric Medicine. 6: 138-140. PMID 27708709 DOI: 10.1258/Om.2012.120030 |
0.381 |
|
| 2013 |
Walker I, Chappell LC, Williamson C. Abnormal liver function tests in pregnancy. Bmj (Clinical Research Ed.). 347: f6055. PMID 24162941 DOI: 10.1136/Bmj.F6055 |
0.4 |
|
| 2013 |
Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, Owen BM, Nikolova V, Ovadia C, Huang X, Vaarasmaki M, Baumann M, Jansen E, Albrecht C, Jarvelin MR, Marin JJ, Knisely AS, ... Williamson C, et al. Maternal cholestasis during pregnancy programs metabolic disease in offspring. The Journal of Clinical Investigation. 123: 3172-81. PMID 23934127 DOI: 10.1172/Jci68927 |
0.439 |
|
| 2013 |
Keitel V, Spomer L, Marin JJG, Williamson C, Geenes V, Kubitz R, Häussinger D, Macias RIR. Effect of maternal cholestasis on TGR5 expression in human and rat placenta at term. Placenta. 34: 810-816. PMID 23849932 DOI: 10.1016/J.Placenta.2013.06.302 |
0.419 |
|
| 2013 |
Frise CJ, Williamson C. Gastrointestinal and liver disease in pregnancy. Clinical Medicine (London, England). 13: 269-74. PMID 23760701 DOI: 10.1016/J.Ogrm.2017.01.005 |
0.434 |
|
| 2013 |
Chappell LC, Williamson C. Liver: Links between hepatobiliary diseases in and beyond pregnancy. Nature Reviews. Gastroenterology & Hepatology. 10: 387-8. PMID 23712314 DOI: 10.1038/Nrgastro.2013.92 |
0.378 |
|
| 2013 |
Frise CJ, Williamson C. Endocrine disease in pregnancy. Clinical Medicine (London, England). 13: 176-81. PMID 23681868 DOI: 10.7861/Clinmedicine.13-2-176 |
0.457 |
|
| 2013 |
Zhang JH, Nolan JD, Kennie SL, Johnston IM, Dew T, Dixon PH, Williamson C, Walters JR. Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G940-8. PMID 23518683 DOI: 10.1152/Ajpgi.00398.2012 |
0.343 |
|
| 2013 |
Abu-Hayyeh S, Papacleovoulou G, Williamson C. Nuclear receptors, bile acids and cholesterol homeostasis series - bile acids and pregnancy. Molecular and Cellular Endocrinology. 368: 120-8. PMID 23159988 DOI: 10.1016/J.Mce.2012.10.027 |
0.527 |
|
| 2013 |
Frise CJ, Mackillop L, Joash K, Williamson C. Starvation ketoacidosis in pregnancy. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 167: 1-7. PMID 23131345 DOI: 10.1016/J.Ejogrb.2012.10.005 |
0.44 |
|
| 2013 |
Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C. Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype. Hepatology (Baltimore, Md.). 57: 716-26. PMID 22961653 DOI: 10.1002/Hep.26055 |
0.528 |
|
| 2013 |
Kennie S, Nolan JD, Zhang JH, Johnston IM, Dixon PH, Williamson C, Walters JR. Su2040 Relative Potencies of Bile Acids in Inducing Fibroblast Growth Factor 19 in the Human Ileum Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)62002-8 |
0.36 |
|
| 2012 |
Chappell LC, Gurung V, Seed PT, Chambers J, Williamson C, Thornton JG. Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial. Bmj (Clinical Research Ed.). 344: e3799. PMID 22695903 DOI: 10.1136/Bmj.E3799 |
0.416 |
|
| 2012 |
Langendonk JG, Roos JCP, Angus L, Williams M, Karstens FPJ, De Klerk JBC, Maritz C, Ben-Omran T, Williamson C, Lachmann RH, Murphy E. A series of pregnancies in women with inherited metabolic disease Journal of Inherited Metabolic Disease. 35: 419-424. PMID 21918856 DOI: 10.1007/S10545-011-9389-2 |
0.433 |
|
| 2012 |
Nolan JD, Zhang JH, Johnston I, Kennie S, Dew T, Dixon P, Williamson C, Walters JR. OC-079 FGF19 expression is highly responsive to bile acids compared to other bile acid regulatory genes within the human ileum Gut. 61. DOI: 10.1136/Gutjnl-2012-302514A.79 |
0.311 |
|
| 2012 |
Zhang JH, Nolan JD, Johnston I, Kennie S, Dew T, Dixon PH, Williamson C, Walters JR. Sa1303 Dramatic Stimulation of Fibroblast Growth Factor 19 Expression in the Human Ileum by Bile Acids Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)61010-5 |
0.341 |
|
| 2011 |
Webster JR, Chappell L, Cheng F, Breeze AC, Lucas N, Plaat F, Williamson C. Operative delivery rates following induction of labour for obstetric cholestasis. Obstetric Medicine. 4: 66-9. PMID 27582856 DOI: 10.1258/Om.2011.110080 |
0.335 |
|
| 2011 |
Geenes VL, Lim YH, Bowman N, Tailor H, Dixon PH, Chambers J, Brown L, Wyatt-Ashmead J, Bhakoo K, Williamson C. A placental phenotype for intrahepatic cholestasis of pregnancy. Placenta. 32: 1026-32. PMID 22015023 DOI: 10.1016/J.Placenta.2011.09.006 |
0.557 |
|
| 2011 |
Nelson-Piercy C, Mackillop L, Williams DJ, Williamson C, Swiet Md, Redman C. Maternal mortality in the UK and the need for obstetric physicians. Bmj. 343. PMID 21828209 DOI: 10.1136/Bmj.D4993 |
0.364 |
|
| 2011 |
Miragoli M, Kadir SH, Sheppard MN, Salvarani N, Virta M, Wells S, Lab MJ, Nikolaev VO, Moshkov A, Hague WM, Rohr S, Williamson C, Gorelik J. A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology (Baltimore, Md.). 54: 1282-92. PMID 21809354 DOI: 10.1002/Hep.24492 |
0.769 |
|
| 2011 |
Williamson C, Miragoli M, Sheikh Abdul Kadir S, Abu-Hayyeh S, Papacleovoulou G, Geenes V, Gorelik J. Bile acid signaling in fetal tissues: implications for intrahepatic cholestasis of pregnancy. Digestive Diseases (Basel, Switzerland). 29: 58-61. PMID 21691106 DOI: 10.1159/000324130 |
0.787 |
|
| 2011 |
Geenes VL, Dixon PH, Chambers J, Raguz S, Marin JJ, Bhakoo KK, Williamson C. Characterisation of the nuclear receptors FXR, PXR and CAR in normal and cholestatic placenta. Placenta. 32: 535-7. PMID 21596433 DOI: 10.1016/J.Placenta.2011.04.014 |
0.391 |
|
| 2011 |
Cantwell R, Clutton-Brock T, Cooper G, Dawson A, Drife J, Garrod D, Harper A, Hulbert D, Lucas S, McClure J, Millward-Sadler H, Neilson J, Nelson-Piercy C, Norman J, O'Herlihy C, ... ... Williamson C, et al. Saving Mothers' Lives: Reviewing maternal deaths to make motherhood safer: 2006-2008. The Eighth Report of the Confidential Enquiries into Maternal Deaths in the United Kingdom. Bjog : An International Journal of Obstetrics and Gynaecology. 118: 1-203. PMID 21356004 DOI: 10.1111/J.1471-0528.2010.02847.X |
0.36 |
|
| 2011 |
Woods A, Heslegrave AJ, Muckett PJ, Levene AP, Clements M, Mobberley M, Ryder TA, Abu-Hayyeh S, Williamson C, Goldin RD, Ashworth A, Withers DJ, Carling D. LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice. The Biochemical Journal. 434: 49-60. PMID 21118154 DOI: 10.1042/Bj20101721 |
0.348 |
|
| 2011 |
Papacleovoulou G, Abu-Hayyeh S, Williamson C. Nuclear receptor-driven alterations in bile acid and lipid metabolic pathways during gestation. Biochimica Et Biophysica Acta. 1812: 879-887. PMID 21073948 DOI: 10.1016/J.Bbadis.2010.11.001 |
0.433 |
|
| 2011 |
Chrisoulidou A, Goulis DG, Iliadou PK, Dave JR, Bili H, Simms C, Redman CWG, Williamson C. Acute and chronic Chlamydia pneumoniae infection in pregnancy complicated with preeclampsia. Hypertension in Pregnancy. 30: 164-168. PMID 20849251 DOI: 10.3109/10641955.2010.506235 |
0.331 |
|
| 2011 |
Chappell LC, Gurung V, Chambers J, Seed PT, Williamson C, Thornton JG. Pitch: Two randomised controlled trials in obstetric cholestasis: ursodeoxycholic acid versus placebo and early delivery versus expectant management Archives of Disease in Childhood-Fetal and Neonatal Edition. 96. DOI: 10.1136/Adc.2011.300163.47 |
0.373 |
|
| 2011 |
Gurung V, Chappell LC, Chambers J, Seed P, Williamson C, Thornton JG. Management and complications of 343 women with obstetric cholestasis in the united kingdom in 2009–2010 Archives of Disease in Childhood-Fetal and Neonatal Edition. 96. DOI: 10.1136/Adc.2011.300163.1 |
0.367 |
|
| 2011 |
Dixon PH, Wadsworth C, Chambers J, Donnelly J, Cooley S, Jarvis S, Kubitz R, Lammert F, Marschall H-, Glantz A, Khan S, Whittaker J, Geary M, Williamson C. Intrahepatic cholestasis of pregnancy – a candidate gene study Archives of Disease in Childhood-Fetal and Neonatal Edition. 96. DOI: 10.1136/Adc.2011.300160.11 |
0.307 |
|
| 2011 |
Kremer AE, Dixon PH, Ris-Stalpers C, Geenes V, Chambers J, Post JAvd, Williamson C, Beuers U, Elferink RPO. 24 Autotaxin Is A Novel Diagnostic Marker For Intrahepatic Cholestasis Of Pregnancy Journal of Hepatology. 54. DOI: 10.1016/S0168-8278(11)60026-3 |
0.42 |
|
| 2011 |
Pattni SS, Pathmasrirengan S, Dixon PH, Williamson C, Walters JR. A Study of the Prevalence of Genetic Polymorphisms in Bile Acid Diarrhea Patients Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)62751-0 |
0.339 |
|
| 2010 |
Kenyon AP, Tribe RM, Nelson-Piercy C, Girling JC, Williamson C, Seed PT, Vaughan-Jones S, Shennan AH. Pruritus in pregnancy: a study of anatomical distribution and prevalence in relation to the development of obstetric cholestasis. Obstetric Medicine. 3: 25-9. PMID 27582836 DOI: 10.1258/Om.2010.090055 |
0.341 |
|
| 2010 |
Nijher GM, Chaudhri OB, Ramachandran R, Murphy KG, Zac-Varghese SE, Fowler A, Chinthapalli K, Patterson M, Thompson EL, Williamson C, Kumar S, Ghatei MA, Bloom SR, Dhillo WS. The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy. British Journal of Clinical Pharmacology. 70: 674-81. PMID 21039761 DOI: 10.1111/J.1365-2125.2010.03746.X |
0.365 |
|
| 2010 |
Milona A, Owen BM, Cobbold JF, Willemsen EC, Cox IJ, Boudjelal M, Cairns W, Schoonjans K, Taylor-Robinson SD, Klomp LW, Parker MG, White R, van Mil SW, Williamson C. Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function. Hepatology (Baltimore, Md.). 52: 1341-9. PMID 20842631 DOI: 10.1002/Hep.23849 |
0.482 |
|
| 2010 |
Kremer AE, Martens JJ, Kulik W, Ruëff F, Kuiper EM, van Buuren HR, van Erpecum KJ, Kondrackiene J, Prieto J, Rust C, Geenes VL, Williamson C, Moolenaar WH, Beuers U, Oude Elferink RP. Lysophosphatidic acid is a potential mediator of cholestatic pruritus. Gastroenterology. 139: 1008-18, 1018.e1. PMID 20546739 DOI: 10.1053/J.Gastro.2010.05.009 |
0.304 |
|
| 2010 |
Nijher GM, Baxter JE, Chaudhri OB, Murphy KG, Ramachandran R, Fowler A, Chinthapalli K, Patterson M, Jayasena CN, Williamson C, Kumar S, Ghatei MA, Bloom SR, Dhillo WS. Identification of the hormone kisspeptin in amniotic fluid. Clinical Chemistry. 56: 1029-31. PMID 20348399 DOI: 10.1373/Clinchem.2009.141879 |
0.371 |
|
| 2010 |
Sheikh Abdul Kadir SH, Miragoli M, Abu-Hayyeh S, Moshkov AV, Xie Q, Keitel V, Nikolaev VO, Williamson C, Gorelik J. Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes. Plos One. 5: e9689. PMID 20300620 DOI: 10.1371/Journal.Pone.0009689 |
0.786 |
|
| 2010 |
Mackillop L, Williamson C. Liver disease in pregnancy. Postgraduate Medical Journal. 86: 160-4. PMID 20237010 DOI: 10.1136/pgmj.2009.089631 |
0.329 |
|
| 2010 |
Abu-Hayyeh S, Martinez-Becerra P, Sheikh Abdul Kadir SH, Selden C, Romero MR, Rees M, Marschall HU, Marin JJ, Williamson C. Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites. The Journal of Biological Chemistry. 285: 16504-12. PMID 20177056 DOI: 10.1074/Jbc.M109.072140 |
0.415 |
|
| 2010 |
King NM, Chambers J, O'Donnell K, Jayaweera SR, Williamson C, Glover VA. Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy. Archives of Women's Mental Health. 13: 339-45. PMID 20101421 DOI: 10.1007/S00737-009-0139-5 |
0.315 |
|
| 2010 |
Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C. The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G151-8. PMID 19815629 DOI: 10.1152/Ajpgi.00336.2009 |
0.455 |
|
| 2010 |
Owen BM, Milona A, van Mil S, Clements P, Holder J, Boudjelal M, Cairns W, Parker M, White R, Williamson C. Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 143-9. PMID 19797606 DOI: 10.1124/Dmd.109.029306 |
0.335 |
|
| 2010 |
Papacleovoulou G, Milona A, Owen B, Jansen E, Williamson C. P42 Cholestatic pregnancy alters cholesterol and lipid transport to the fetal circulation, affecting lipid metabolism of the fetus Gut. 59. DOI: 10.1136/Gut.2010.223362.68 |
0.483 |
|
| 2010 |
Adjene A, Comninos A, Troke R, Badman MK, Hensman D, Spalding D, Williamson C, Todd JF, Meeran K, Tan T. The difficulties of managing an insulinoma in pregnancy Regulatory Peptides. 164: 13. DOI: 10.1016/J.Regpep.2010.07.039 |
0.376 |
|
| 2009 |
Gurung V, Williamson C, Chappell L, Chambers J, Briley A, Broughton Pipkin F, Thornton J. Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis. Bmc Pregnancy and Childbirth. 9: 19. PMID 19445704 DOI: 10.1186/1471-2393-9-19 |
0.42 |
|
| 2009 |
Abdul Kadir SH, Ali NN, Mioulane M, Brito-Martins M, Abu-Hayyeh S, Foldes G, Moshkov AV, Williamson C, Harding SE, Gorelik J. Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease. Journal of Cellular and Molecular Medicine. 13: 3730-41. PMID 19438812 DOI: 10.1111/J.1582-4934.2009.00741.X |
0.774 |
|
| 2009 |
Geenes V, Williamson C. Intrahepatic cholestasis of pregnancy. World Journal of Gastroenterology. 15: 2049-66. PMID 19418576 DOI: 10.3748/wjg.15.2049 |
0.391 |
|
| 2009 |
Banerjee A, Wynne K, Tan T, Hatfield EC, Martin NM, Williamson C, Meeran K. High dose cabergoline therapy for a resistant macroprolactinoma during pregnancy. Clinical Endocrinology. 70: 812-3. PMID 18803677 DOI: 10.1111/J.1365-2265.2008.03425.X |
0.319 |
|
| 2008 |
Dixon PH, Williamson C. The molecular genetics of intrahepatic cholestasis of pregnancy. Obstetric Medicine. 1: 65-71. PMID 27582788 DOI: 10.1258/Om.2008.080010 |
0.402 |
|
| 2008 |
Owen BM, Van Mil SW, Boudjelal M, McLay I, Cairns W, Elias E, White R, Williamson C, Dixon PH. Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 38: 1289-97. PMID 18800312 DOI: 10.1080/00498250802426114 |
0.358 |
|
| 2008 |
Kadir SHS, Abu-Hayyeh S, Williamson C, Gorelik J. Mechanisms of bile acid signalling in cardiomyocytes Journal of Molecular and Cellular Cardiology. 44: 774-775. DOI: 10.1016/J.Yjmcc.2008.02.152 |
0.717 |
|
| 2008 |
Kadir SHSA, Ali NN, Abu-Hayyeh S, Harding SE, Williamson C, Gorelik J. The use of embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease Journal of Molecular and Cellular Cardiology. 44: 774. DOI: 10.1016/J.Yjmcc.2008.02.151 |
0.712 |
|
| 2007 |
Van Mil SW, Milona A, Dixon PH, Mullenbach R, Geenes VL, Chambers J, Shevchuk V, Moore GE, Lammert F, Glantz AG, Mattsson LA, Whittaker J, Parker MG, White R, Williamson C. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology. 133: 507-16. PMID 17681172 DOI: 10.1053/J.Gastro.2007.05.015 |
0.421 |
|
| 2007 |
Broughton Pipkin F, Kalsheker N, Morgan L, O'Malley S, Henfrey M, Arulkumaran S, Symonds I, Cameron A, Dominiczak A, McDade M, Kwong Lee W, McCulloch J, Caulfield M, Farrall M, Kilby M, ... ... Williamson C, et al. Babies, pre-eclamptic mothers and grandparents: A three-generation phenotyping study Journal of Hypertension. 25: 849-854. PMID 17351378 DOI: 10.1097/Hjh.0B013E32803Fb634 |
0.31 |
|
| 2007 |
Albrecht C, Soumian S, Tetlow N, Patel P, Sullivan MHF, Lakasing L, Nicolaides K, Williamson C. Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls Placenta. 28: 701-708. PMID 17113147 DOI: 10.1016/J.Placenta.2006.10.001 |
0.345 |
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| 2006 |
Gorelik J, Ali NN, Shevchuk AI, Lab M, Williamson C, Harding SE, Korchev YE. Functional characterization of embryonic stem cell-derived cardiomyocytes using scanning ion conductance microscopy Tissue Engineering. 12: 657-664. PMID 16674281 DOI: 10.1089/Ten.2006.12.657 |
0.666 |
|
| 2006 |
Gorelik J, Patel P, Ng'andwe C, Vodyanoy I, Diakonov I, Lab M, Korchev Y, Williamson C. Basic science: Genes encoding bile acid, phospholipid and anion transporters are expressed in a human fetal cardiomyocyte culture British Journal of Obstetrics and Gynaecology. 113: 552-558. PMID 16637898 DOI: 10.1111/J.1471-0528.2006.00918.X |
0.741 |
|
| 2006 |
Diac M, Kenyon A, Nelson-Piercy C, Girling J, Cheng F, Tribe RM, Goodman J, Shennan A, Williamson C. Dexamethasone in the treatment of obstetric cholestasis: a case series. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology. 26: 110-4. PMID 16483964 DOI: 10.1080/01443610500443246 |
0.342 |
|
| 2006 |
Varanou A, Withington SL, Lakasing L, Williamson C, Burton GJ, Hemberger M. The importance of cysteine cathepsin proteases for placental development. Journal of Molecular Medicine (Berlin, Germany). 84: 305-17. PMID 16440214 DOI: 10.1007/S00109-005-0032-2 |
0.344 |
|
| 2005 |
Müllenbach R, Bennett A, Tetlow N, Patel N, Hamilton G, Cheng F, Chambers J, Howard R, Taylor-Robinson SD, Williamson C. ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy Gut. 54: 829-834. PMID 15888793 DOI: 10.1136/Gut.2004.058115 |
0.387 |
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| 2005 |
Lakasing L, Williamson C. Obstetric complications due to autoantibodies Best Practice & Research Clinical Endocrinology & Metabolism. 19: 149-175. PMID 15826928 DOI: 10.1016/J.Beem.2004.11.014 |
0.348 |
|
| 2005 |
Goulis DG, Chappell L, Gibbs RGJ, Williams D, Dave JR, Taylor P, Swiet MD, Poston L, Williamson C. Association of raised titres of antibodies to Chlamydia pneumoniae with a history of pre-eclampsia British Journal of Obstetrics and Gynaecology. 112: 299-305. PMID 15713143 DOI: 10.1111/J.1471-0528.2004.00423.X |
0.305 |
|
| 2004 |
Miller NM, Williamson C, Fisk NM, Glover V. Infant cortisol response after prolonged antenatal prednisolone treatment Bjog: An International Journal of Obstetrics and Gynaecology. 111: 1471-1474. PMID 15663140 DOI: 10.1111/J.1471-0528.2004.00288.X |
0.314 |
|
| 2004 |
Gorelik J, Shevchuk A, Swiet Md, Lab M, Korchev Y, Williamson C. Comparison of the arrhythmogenic effects of tauro‐ and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes British Journal of Obstetrics and Gynaecology. 111: 867-870. PMID 15270939 DOI: 10.1111/J.1471-0528.2004.00166.X |
0.772 |
|
| 2004 |
Williamson C, Hems LM, Goulis DG, Walker I, Chambers J, Donaldson O, Swiet M, Johnston DG. Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group. Bjog : An International Journal of Obstetrics and Gynaecology. 111: 676-81. PMID 15198757 DOI: 10.1111/J.1471-0528.2004.00167.X |
0.425 |
|
| 2004 |
Goulis DG, Walker IA, de Swiet M, Redman CW, Williamson C. Preeclampsia with abnormal liver function tests is associated with cholestasis in a subgroup of cases. Hypertension in Pregnancy. 23: 19-27. PMID 15117597 DOI: 10.1081/Prg-120028278 |
0.421 |
|
| 2003 |
Chrisoulidou A, Williamson C, Swiet MD. Assessment of adrenocortical function in women taking exogenous glucocorticoids during pregnancy. Journal of Obstetrics and Gynaecology. 23: 643-644. PMID 14617468 DOI: 10.1080/01443610310001607481 |
0.378 |
|
| 2003 |
Savander M, Ropponen A, Avela K, Weerasekera N, Cormand B, Hirvioja ML, Riikonen S, Ylikorkala O, Lehesjoki AE, Williamson C, Aittomäki K. Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy. Gut. 52: 1025-9. PMID 12801961 DOI: 10.1136/Jmg.40.8.640 |
0.392 |
|
| 2003 |
Müllenbach R, Linton KJ, Wiltshire S, Weerasekera N, Chambers J, Elias E, Higgins CF, Johnston DG, McCarthy MI, Williamson C. ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy Journal of Medical Genetics. 40. PMID 12746424 DOI: 10.1136/Jmg.40.5.E70 |
0.478 |
|
| 2003 |
Patel P, Weerasekera N, Hitchins M, Boyd CA, Johnston DG, Williamson C. Semi quantitative expression analysis of MDR3, FIC1, BSEP, OATP-A, OATP-C,OATP-D, OATP-E and NTCP gene transcripts in 1st and 3rd trimester human placenta. Placenta. 24: 39-44. PMID 12495658 DOI: 10.1053/Plac.2002.0879 |
0.313 |
|
| 2003 |
Kenyon AP, Dann AT, Girling J, Nelson-Piercy C, Williamson C, Tribe R, Shennan AH. Cord liver function and bile acids in actively managed obstetric cholestasis (OC) are not abnormal Journal of Obstetrics and Gynaecology. 23: S47-S48. DOI: 10.1080/713938725 |
0.442 |
|
| 2003 |
Gorelik J, Shevchuk AI, Diakonov I, Swiet Md, Lab M, Korchev Y, Williamson C. Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes. British Journal of Obstetrics and Gynaecology. 110: 467-474. DOI: 10.1046/J.1471-0528.2003.02273.X |
0.731 |
|
| 2003 |
Mullenbach R, Linton KJ, Wiltshire S, Elias E, McCarthy MI, Williamson C. ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy Journal of Hepatology. 38: 213-213. DOI: 10.1016/S0168-8278(03)80114-9 |
0.361 |
|
| 2002 |
Gorelik J, Harding SE, Shevchuk AI, Koralage D, Lab M, de Swiet M, Korchev Y, Williamson C. Taurocholate induces changes in rat cardiomyocyte contraction and calcium dynamics. Clinical Science (London, England : 1979). 103: 191-200. PMID 12149111 DOI: 10.1042/Cs1030191 |
0.749 |
|
| 2002 |
Kenyon AP, Piercy CN, Girling J, Williamson C, Tribe RM, Shennan AH. Obstetric cholestasis, outcome with active management: a series of 70 cases. Bjog : An International Journal of Obstetrics and Gynaecology. 109: 282-8. PMID 11950183 DOI: 10.1111/J.1471-0528.2002.01368.X |
0.363 |
|
| 2002 |
Walker IA, Nelson-Piercy C, Williamson C. Role of bile acid measurement in pregnancy. Annals of Clinical Biochemistry. 39: 105-13. PMID 11928758 DOI: 10.1258/0004563021901856 |
0.518 |
|
| 2002 |
Germain AM, Carvajal JA, Glasinovic JC, Kato CS, Williamson C. Intrahepatic Cholestasis of Pregnancy: An Intriguing Pregnancy-Specific Disorder Journal of the Society For Gynecologic Investigation. 9: 10-14. PMID 11839502 DOI: 10.1016/S1071-5576(01)00144-7 |
0.47 |
|
| 2002 |
Milkiewicz P, Elias E, Williamson C, Weaver J. Obstetric cholestasis: May have serious consequences for the fetus, and needs to be taken seriously Bmj. 324: 123-124. PMID 11799014 DOI: 10.1136/Bmj.324.7330.123 |
0.438 |
|
| 2001 |
Williamson C. Drugs in pregnancy. Gastrointestinal disease. Best Practice & Research in Clinical Obstetrics & Gynaecology. 15: 937-952. PMID 11800534 DOI: 10.1053/Beog.2001.0239 |
0.435 |
|
| 2001 |
Kenyon AP, Piercy CN, Girling J, Williamson C, Tribe RM, Shennan AH. Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis. Bjog : An International Journal of Obstetrics and Gynaecology. 108: 1190-2. PMID 11762661 DOI: 10.1111/J.1471-0528.2003.00281.X |
0.415 |
|
| 2001 |
Williamson C, Gorelik J, Eaton BM, Lab M, Swiet Md, Korchev Y. The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis. Clinical Science. 100: 363-369. DOI: 10.1042/Cs1000363 |
0.791 |
|
| 2000 |
Dixon PH, Weerasekera N, Linton KJ, Donaldson O, Chambers J, Egginton E, Weaver J, Nelson-Piercy C, de Swiet M, Warnes G, Elias E, Higgins CF, Johnston DG, McCarthy MI, Williamson C. Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Human Molecular Genetics. 9: 1209-17. PMID 10767346 DOI: 10.1093/Hmg/9.8.1209 |
0.347 |
|
| 1996 |
Priddy AR, Williamson C, Worsley A, Sharp P. Spontaneous conception and vaginal delivery in a woman with salt-losing congenital adrenal hyperplasia Journal of Obstetrics and Gynaecology. 16: 89-90. DOI: 10.3109/01443619609007747 |
0.327 |
|
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