Rebecca A. Splain, Ph.D.
Affiliations: | 2011-2014 | Chemistry | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
| 2014- | GlaxoSmithKline, Collegeville, PA, United States |
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"Rebecca Splain"Mean distance: 7.63 | S | N | B | C | P |
Parents
Sign in to add mentor| Laura Lee Kiessling | grad student | 2005-2011 | UW Madison | |
| (Synthesis of galactofuranose-based acceptor substrates for the study of galactan biosynthesis.) | ||||
| Wilfred A. van der Donk | post-doc | 2011-2014 | UIUC | |
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Publications
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| Daniels PN, Lee H, Splain RA, et al. (2021) A biosynthetic pathway to aromatic amines that uses glycyl-tRNA as nitrogen donor. Nature Chemistry |
| Yamatsugu K, Splain RA, Kiessling LL. (2016) Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase. Journal of the American Chemical Society. 138: 9205-11 |
| Wesener DA, Wangkanont K, McBride R, et al. (2015) Recognition of microbial glycans by human intelectin-1. Nature Structural & Molecular Biology. 22: 603-10 |
| May JF, Levengood MR, Splain RA, et al. (2012) A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site. Biochemistry. 51: 1148-59 |
| Levengood MR, Splain RA, Kiessling LL. (2011) Monitoring processivity and length control of a carbohydrate polymerase. Journal of the American Chemical Society. 133: 12758-66 |
| Splain RA, Kiessling LL. (2010) Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2. Bioorganic & Medicinal Chemistry. 18: 3753-9 |
| Kiessling LL, Splain RA. (2010) Chemical approaches to glycobiology. Annual Review of Biochemistry. 79: 619-53 |
| May JF, Splain RA, Brotschi C, et al. (2009) A tethering mechanism for length control in a processive carbohydrate polymerization. Proceedings of the National Academy of Sciences of the United States of America. 106: 11851-6 |