Year |
Citation |
Score |
2023 |
Wang Y, Barthez M, Chen D. Mitochondrial regulation in stem cells. Trends in Cell Biology. PMID 37919163 DOI: 10.1016/j.tcb.2023.10.003 |
0.313 |
|
2023 |
Wang CL, Ohkubo R, Mu WC, Chen W, Fan JL, Song Z, Maruichi A, Sudmant PH, Pisco AO, Dubal DB, Ji N, Chen D. The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging. Cell Metabolism. PMID 37146607 DOI: 10.1016/j.cmet.2023.04.012 |
0.302 |
|
2020 |
Wei-Chieh M, Ohkubo R, Widjaja A, Chen D. The Mitochondrial Metabolic Checkpoint in Stem Cell Aging and Rejuvenation. Mechanisms of Ageing and Development. 111254. PMID 32343979 DOI: 10.1016/J.Mad.2020.111254 |
0.448 |
|
2020 |
He M, Chiang HH, Luo H, Zheng Z, Qiao Q, Wang L, Tan M, Ohkubo R, Mu WC, Zhao S, Wu H, Chen D. An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance. Cell Metabolism. PMID 32032542 DOI: 10.1016/J.Cmet.2020.01.009 |
0.354 |
|
2019 |
Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, et al. Latest advances in aging research and drug discovery. Aging. 11. PMID 31770722 DOI: 10.18632/Aging.102487 |
0.36 |
|
2019 |
Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, et al. To help aging populations, classify organismal senescence. Science (New York, N.Y.). 366: 576-578. PMID 31672885 DOI: 10.1126/Science.Aay7319 |
0.316 |
|
2019 |
Chen D, Kerr C. The Epigenetics of Stem Cell Aging Comes of Age. Trends in Cell Biology. PMID 31030975 DOI: 10.1016/J.Tcb.2019.03.006 |
0.412 |
|
2019 |
Luo H, Mu WC, Karki R, Chiang HH, Mohrin M, Shin JJ, Ohkubo R, Ito K, Kanneganti TD, Chen D. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Reports. 26: 945-954.e4. PMID 30673616 DOI: 10.1016/J.Celrep.2018.12.101 |
0.47 |
|
2018 |
Mohrin M, Widjaja A, Liu Y, Luo H, Chen D. The mitochondrial unfolded protein response is activated upon hematopoietic stem cell exit from quiescence. Aging Cell. e12756. PMID 29575576 DOI: 10.1111/Acel.12756 |
0.376 |
|
2017 |
Ohkubo R, Chen D. Aging: rewiring the circadian clock. Nature Structural & Molecular Biology. 24: 687-688. PMID 28880862 DOI: 10.1038/Nsmb.3461 |
0.392 |
|
2017 |
Luo H, Chiang HH, Louw M, Susanto A, Chen D. Nutrient Sensing and the Oxidative Stress Response. Trends in Endocrinology and Metabolism: Tem. PMID 28314502 DOI: 10.1016/J.Tem.2017.02.008 |
0.389 |
|
2016 |
Shin J, Chen D. Molecular, Cellular, and Physiological Characterization of Sirtuin 7 (SIRT7). Methods in Molecular Biology (Clifton, N.J.). 1436: 271-7. PMID 27246221 DOI: 10.1007/978-1-4939-3667-0_18 |
0.331 |
|
2016 |
Mohrin M, Chen D. The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells. Current Opinion in Hematology. PMID 26945277 DOI: 10.1097/Moh.0000000000000244 |
0.419 |
|
2016 |
Chen D. The Mitochondrial Metabolic Checkpoint and Reversing Stem Cell Aging Blood. 128: SCI-34-SCI-34. DOI: 10.1182/blood.v128.22.sci-34.sci-34 |
0.337 |
|
2015 |
Shin J, Mohrin M, Chen D. Reversing stem cell aging. Oncotarget. PMID 26062656 DOI: 10.18632/Oncotarget.4403 |
0.394 |
|
2015 |
Mohrin M, Shin J, Liu Y, Brown K, Luo H, Xi Y, Haynes CM, Chen D. Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging. Science (New York, N.Y.). 347: 1374-7. PMID 25792330 DOI: 10.1126/Science.Aaa2361 |
0.468 |
|
2013 |
Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy AJ, Valenzuela DM, Luo H, ... ... Chen D, et al. SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease. Cell Reports. 5: 654-65. PMID 24210820 DOI: 10.1016/J.Celrep.2013.10.007 |
0.303 |
|
2013 |
Mohrin M, Chen D. Sirtuins, tissue maintenance, and tumorigenesis. Genes & Cancer. 4: 76-81. PMID 24019997 DOI: 10.1177/1947601912474930 |
0.366 |
|
2013 |
Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E. The sirtuins, oxidative stress and aging: an emerging link. Aging. 5: 144-50. PMID 23474711 |
0.311 |
|
2013 |
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D. SIRT3 reverses aging-associated degeneration. Cell Reports. 3: 319-27. PMID 23375372 DOI: 10.1016/J.Celrep.2013.01.005 |
0.478 |
|
2013 |
Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy A, Valenzuela D, Luo H, ... ... Chen D, et al. Correction to SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease. [Cell Reports 5, 7, (2013)] 654-665 Cell Reports. 5: 1479. DOI: 10.1016/J.Celrep.2013.11.036 |
0.308 |
|
2012 |
Brown K, Liu Y, Chen D. Aging: The Mitochondrial Connection Experimental Pathology. 2: 1-6. DOI: 10.4172/2161-0681.S4-003 |
0.367 |
|
2011 |
Zhang D, Liu Y, Chen D. SIRT-ain relief from age-inducing stress. Aging. 3: 158-61. PMID 21307404 |
0.306 |
|
2010 |
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metabolism. 12: 662-7. PMID 21109198 DOI: 10.1016/J.Cmet.2010.11.015 |
0.351 |
|
2010 |
Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, et al. Dietary restriction: standing up for sirtuins. Science (New York, N.Y.). 329: 1012-3; author reply. PMID 20798296 DOI: 10.1126/Science.329.5995.1012 |
0.319 |
|
2010 |
Qiu X, Brown KV, Moran Y, Chen D. Sirtuin regulation in calorie restriction. Biochimica Et Biophysica Acta. 1804: 1576-83. PMID 19782772 DOI: 10.1016/J.Bbapap.2009.09.015 |
0.301 |
|
2008 |
Chen D, Steele AD, Hutter G, Bruno J, Govindarajan A, Easlon E, Lin SJ, Aguzzi A, Lindquist S, Guarente L. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Experimental Gerontology. 43: 1086-93. PMID 18799131 DOI: 10.1016/J.Exger.2008.08.050 |
0.304 |
|
2008 |
Nakahata Y, Kaluzova M, Grimaldi B, Sahar S, Hirayama J, Chen D, Guarente LP, Sassone-Corsi P. The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell. 134: 329-40. PMID 18662547 DOI: 10.1016/J.Cell.2008.07.002 |
0.311 |
|
2008 |
Chen D, Bruno J, Easlon E, Lin SJ, Cheng HL, Alt FW, Guarente L. Tissue-specific regulation of SIRT1 by calorie restriction. Genes & Development. 22: 1753-7. PMID 18550784 DOI: 10.1101/Gad.1650608 |
0.322 |
|
2007 |
Chen D, Guarente L. SIR2: a potential target for calorie restriction mimetics. Trends in Molecular Medicine. 13: 64-71. PMID 17207661 DOI: 10.1016/J.Molmed.2006.12.004 |
0.376 |
|
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