| Year |
Citation |
Score |
| 2020 |
Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, Katz II, Yu H, Xiong W, Hu F. Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice. Embo Reports. e50219. PMID 32852886 DOI: 10.15252/Embr.202050219 |
0.412 |
|
| 2020 |
Feng T, Sheng RR, Solé-Domènech S, Ullah M, Zhou X, Mendoza CS, Enriquez LCM, Katz II, Paushter DH, Sullivan PM, Wu X, Maxfield FR, Hu F. A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination. Brain : a Journal of Neurology. PMID 32572497 DOI: 10.1093/Brain/Awaa154 |
0.429 |
|
| 2019 |
Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F. Progranulin deficiency leads to reduced glucocerebrosidase activity. Plos One. 14: e0212382. PMID 31291241 DOI: 10.1371/Journal.Pone.0212382 |
0.336 |
|
| 2019 |
Lan Y, Sullivan PM, Hu F. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. Autophagy. 1-15. PMID 30696333 DOI: 10.1080/15548627.2019.1569914 |
0.356 |
|
| 2018 |
Zhou X, Sullivan PM, Paushter DH, Hu F. The Interaction Between Progranulin with Sortilin and the Lysosome. Methods in Molecular Biology (Clifton, N.J.). 1806: 269-288. PMID 29956282 DOI: 10.1007/978-1-4939-8559-3_18 |
0.333 |
|
| 2018 |
Nicholson AM, Zhou X, Perkerson RB, Parsons TM, Chew J, Brooks M, DeJesus-Hernandez M, Finch NA, Matchett BJ, Kurti A, Jansen-West KR, Perkerson E, Daughrity L, Castanedes-Casey M, Rousseau L, ... ... Hu F, et al. Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity. Acta Neuropathologica Communications. 6: 42. PMID 29855382 DOI: 10.1186/S40478-018-0545-X |
0.334 |
|
| 2018 |
Paushter DH, Du H, Feng T, Hu F. The lysosomal function of progranulin, a guardian against neurodegeneration. Acta Neuropathologica. PMID 29744576 DOI: 10.1007/S00401-018-1861-8 |
0.341 |
|
| 2017 |
Zhou X, Sullivan PM, Sun L, Hu F. The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C. Journal of Neurochemistry. PMID 28640985 DOI: 10.1111/Jnc.14110 |
0.32 |
|
| 2017 |
Zhou X, Sun L, Bracko O, Choi JW, Jia Y, Nana AL, Brady OA, Hernandez JCC, Nishimura N, Seeley WW, Hu F. Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations. Nature Communications. 8: 15277. PMID 28541286 DOI: 10.1038/Ncomms15277 |
0.35 |
|
| 2017 |
Zhou X, Sun L, Brady OA, Murphy KA, Hu F. Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency. Acta Neuropathologica Communications. 5: 9. PMID 28126008 DOI: 10.1186/S40478-017-0412-1 |
0.376 |
|
| 2016 |
Sullivan PM, Zhou X, Robins AM, Paushter DH, Kim D, Smolka MB, Hu F. The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Acta Neuropathologica Communications. 4: 51. PMID 27193190 DOI: 10.1186/S40478-016-0324-5 |
0.328 |
|
| 2015 |
Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F. Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin. The Journal of Cell Biology. 210: 991-1002. PMID 26370502 DOI: 10.1083/Jcb.201502029 |
0.376 |
|
| 2015 |
Hsu F, Hu F, Mao Y. Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling. The Journal of Cell Biology. 209: 97-110. PMID 25869669 DOI: 10.1083/Jcb.201408027 |
0.328 |
|
| 2014 |
Brady OA, Zhou X, Hu F. Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a). The Journal of Biological Chemistry. 289: 19670-80. PMID 24872421 DOI: 10.1074/Jbc.M113.515700 |
0.314 |
|
| 2013 |
Busch JI, Martinez-Lage M, Ashbridge E, Grossman M, Van Deerlin VM, Hu F, Lee VM, Trojanowski JQ, Chen-Plotkin AS. Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain. Acta Neuropathologica Communications. 1: 36. PMID 24252750 DOI: 10.1186/2051-5960-1-36 |
0.372 |
|
| 2013 |
Tian C, Shi H, Xiong S, Hu F, Xiong WC, Liu J. The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans. Development (Cambridge, England). 140: 4070-80. PMID 24004951 DOI: 10.1242/Dev.099838 |
0.42 |
|
| 2013 |
Brady OA, Zheng Y, Murphy K, Huang M, Hu F. The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function. Human Molecular Genetics. 22: 685-95. PMID 23136129 DOI: 10.1093/Hmg/Dds475 |
0.316 |
|
| 2011 |
Zheng Y, Brady OA, Meng PS, Mao Y, Hu F. C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking. Plos One. 6: e21023. PMID 21698296 DOI: 10.1371/Journal.Pone.0021023 |
0.33 |
|
| 2011 |
Brady OA, Meng P, Zheng Y, Mao Y, Hu F. Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1. Journal of Neurochemistry. 116: 248-59. PMID 21062285 DOI: 10.1111/J.1471-4159.2010.07098.X |
0.302 |
|
| 2010 |
Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM. Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron. 68: 654-67. PMID 21092856 DOI: 10.1016/J.Neuron.2010.09.034 |
0.671 |
|
| 2009 |
Mao Y, Balkin DM, Zoncu R, Erdmann KS, Tomasini L, Hu F, Jin MM, Hodsdon ME, De Camilli P. A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism. The Embo Journal. 28: 1831-42. PMID 19536138 DOI: 10.1038/Emboj.2009.155 |
0.331 |
|
| 2008 |
Budel S, Padukkavidana T, Liu BP, Feng Z, Hu F, Johnson S, Lauren J, Park JH, McGee AW, Liao J, Stillman A, Kim JE, Yang BZ, Sodi S, Gelernter J, et al. Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13161-72. PMID 19052207 DOI: 10.1523/Jneurosci.3828-08.2008 |
0.522 |
|
| 2008 |
Hu F, Strittmatter SM. The N-terminal domain of Nogo-A inhibits cell adhesion and axonal outgrowth by an integrin-specific mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1262-9. PMID 18234903 DOI: 10.1523/Jneurosci.1068-07.2008 |
0.603 |
|
| 2007 |
Laurén J, Hu F, Chin J, Liao J, Airaksinen MS, Strittmatter SM. Characterization of myelin ligand complexes with neuronal Nogo-66 receptor family members. The Journal of Biological Chemistry. 282: 5715-25. PMID 17189258 DOI: 10.1074/Jbc.M609797200 |
0.631 |
|
| 2006 |
Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC. Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 10997-1002. PMID 16835300 DOI: 10.1073/Pnas.0602427103 |
0.52 |
|
| 2005 |
Hu F, Liu BP, Budel S, Liao J, Chin J, Fournier A, Strittmatter SM. Nogo-A interacts with the Nogo-66 receptor through multiple sites to create an isoform-selective subnanomolar agonist. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5298-304. PMID 15930377 DOI: 10.1523/Jneurosci.5235-04.2005 |
0.704 |
|
| 2004 |
Hu F, Strittmatter SM. Regulating axon growth within the postnatal central nervous system. Seminars in Perinatology. 28: 371-8. PMID 15693393 DOI: 10.1053/J.Semperi.2004.10.001 |
0.633 |
|
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