Scott T. Eblen - Publications

Affiliations: 
Cell and Molecular Pharmacology Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology, Cell Biology, Pharmacology, Oncology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Williams CB, Phelps-Polirer K, Dingle IP, Williams CJ, Rhett MJ, Eblen ST, Armeson K, Hill EG, Yeh ES. Correction: HUNK phosphorylates EGFR to regulate breast cancer metastasis. Oncogene. PMID 33958726 DOI: 10.1038/s41388-021-01797-3  0.318
2019 Zambrano JN, Eblen ST, Abt M, Rhett JM, Muise-Helmericks R, Yeh ES. HUNK Phosphorylates Rubicon to Support Autophagy. International Journal of Molecular Sciences. 20. PMID 31752345 DOI: 10.3390/Ijms20225813  0.402
2019 Williams CB, Phelps-Polirer K, Dingle IP, Williams CJ, Rhett MJ, Eblen ST, Armeson K, Hill EG, Yeh ES. HUNK phosphorylates EGFR to regulate breast cancer metastasis. Oncogene. PMID 31597954 DOI: 10.1038/S41388-019-1046-5  0.47
2019 Kaur J, Daoud A, Eblen ST. Targeting Chromatin Remodeling for Cancer Therapy. Current Molecular Pharmacology. PMID 30767757 DOI: 10.2174/1874467212666190215112915  0.348
2018 Zambrano JN, Williams CJ, Williams CB, Hedgepeth L, Burger P, Dilday T, Eblen ST, Armeson K, Hill EG, Yeh ES. Staurosporine, an inhibitor of hormonally up-regulated neu-associated kinase. Oncotarget. 9: 35962-35973. PMID 30542510 DOI: 10.18632/Oncotarget.26311  0.5
2018 Eblen ST. Extracellular-Regulated Kinases: Signaling From Ras to ERK Substrates to Control Biological Outcomes. Advances in Cancer Research. 138: 99-142. PMID 29551131 DOI: 10.1016/Bs.Acr.2018.02.004  0.507
2017 Eblen ST, Bradley A. MOAP-1, UBR5 and cisplatin resistance in ovarian cancer. Translational Cancer Research. 6: S18-S21. PMID 29607295 DOI: 10.21037/Tcr.2017.02.01  0.751
2016 Collier JB, Whitaker RM, Eblen ST, Schnellmann RG. Rapid Renal Regulation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α by Extracellular Regulated Kinase 1/2 in Physiological and Pathological Conditions. The Journal of Biological Chemistry. PMID 27875304 DOI: 10.1074/Jbc.M116.754762  0.414
2014 Bradley A, Zheng H, Ziebarth A, Sakati W, Branham-O'Connor M, Blumer JB, Liu Y, Kistner-Griffin E, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Landen CN, Eblen ST. EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer. Carcinogenesis. 35: 1100-9. PMID 24379240 DOI: 10.1093/Carcin/Bgt489  0.778
2013 Ali MW, Cacan E, Liu Y, Pierce JY, Creasman WT, Murph MM, Govindarajan R, Eblen ST, Greer SF, Hooks SB. Transcriptional suppression, DNA methylation, and histone deacetylation of the regulator of G-protein signaling 10 (RGS10) gene in ovarian cancer cells. Plos One. 8: e60185. PMID 23533674 DOI: 10.1371/Journal.Pone.0060185  0.427
2013 Liu Y, Conaway L, Rutherford Bethard J, Al-Ayoubi AM, Thompson Bradley A, Zheng H, Weed SA, Eblen ST. Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion. Nucleic Acids Research. 41: 4949-62. PMID 23519612 DOI: 10.1093/Nar/Gkt170  0.77
2013 Liu Y, Conaway LN, Bethard JR, Bradley AT, Eblen S. Abstract 4283: Src phosphorylates splicing factor 45 (SPF45) and regulates SPF45 nucleocytoplasmic shuttling, cell migration and invasion. Cancer Research. 73: 4283-4283. DOI: 10.1158/1538-7445.Am2013-4283  0.791
2012 Mueller KL, Powell K, Madden JM, Eblen ST, Boerner JL. EGFR Tyrosine 845 Phosphorylation-Dependent Proliferation and Transformation of Breast Cancer Cells Require Activation of p38 MAPK. Translational Oncology. 5: 327-34. PMID 23066441 DOI: 10.1593/Tlo.12163  0.533
2012 Gault CR, Eblen ST, Neumann CA, Hannun YA, Obeid LM. Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner. The Journal of Biological Chemistry. 287: 31794-803. PMID 22833671 DOI: 10.1074/Jbc.M112.385765  0.44
2012 Al-Ayoubi AM, Zheng H, Liu Y, Bai T, Eblen ST. Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion. Molecular and Cellular Biology. 32: 2880-93. PMID 22615491 DOI: 10.1128/Mcb.06327-11  0.776
2012 Eblen ST. Regulation of chemoresistance via alternative messenger RNA splicing. Biochemical Pharmacology. 83: 1063-72. PMID 22248731 DOI: 10.1016/J.Bcp.2011.12.041  0.415
2011 Bethard JR, Zheng H, Roberts L, Eblen ST. Identification of phosphorylation sites on the E3 ubiquitin ligase UBR5/EDD. Journal of Proteomics. 75: 603-9. PMID 21924388 DOI: 10.1016/J.Jprot.2011.08.023  0.481
2011 Liu Y, Al-Ayoubi A, Zheng H, Bethard J, Eblen ST. Abstract 3077: The SR protein kinase Clk1 phosphorylates SPF45 and regulates its localization, degradation and alternative splicing activity Cancer Research. 71: 3077-3077. DOI: 10.1158/1538-7445.Am2011-3077  0.779
2011 Bradley AT, Zheng H, Ziebarth A, Sakati W, Eier S, Lopez-Berestein G, Sood AK, Landen C, Eblen ST. Abstract 1649: The E3 ubiquitin ligase EDD regulates platinum resistance and is a novel therapeutic target for epithelial ovarian cancer Cancer Research. 71: 1649-1649. DOI: 10.1158/1538-7445.Am2011-1649  0.769
2011 Ziebarth A, Zheng H, Bradley A, Sakati W, Eier S, Lopez-Berestein G, Sood A, Eblen S, Landen C. The ubiquitin ligase EDD mediates platinum resistance and is a target for therapy in epithelial ovarian cancer Gynecologic Oncology. 120: S26-S27. DOI: 10.1016/J.Ygyno.2010.12.066  0.744
2010 Zheng H, Al-Ayoubi A, Eblen ST. Identification of novel substrates of MAP Kinase cascades using bioengineered kinases that uniquely utilize analogs of ATP to phosphorylate substrates. Methods in Molecular Biology (Clifton, N.J.). 661: 167-83. PMID 20811983 DOI: 10.1007/978-1-60761-795-2_10  0.743
2010 Li Q, Wu J, Zheng H, Liu K, Guo TL, Liu Y, Eblen ST, Grant S, Zhang S. Discovery of 3-(2-aminoethyl)-5-(3-phenyl-propylidene)-thiazolidine-2,4-dione as a dual inhibitor of the Raf/MEK/ERK and the PI3K/Akt signaling pathways. Bioorganic & Medicinal Chemistry Letters. 20: 4526-30. PMID 20580230 DOI: 10.1016/J.Bmcl.2010.06.030  0.461
2009 Li Q, Al-Ayoubi A, Guo T, Zheng H, Sarkar A, Nguyen T, Eblen ST, Grant S, Kellogg GE, Zhang S. Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 6042-6. PMID 19796943 DOI: 10.1016/J.Bmcl.2009.09.057  0.722
2008 Al-Ayoubi A, Tarcsafalvi A, Zheng H, Sakati W, Eblen ST. ERK activation and nuclear signaling induced by the loss of cell/matrix adhesion stimulates anchorage-independent growth of ovarian cancer cells. Journal of Cellular Biochemistry. 105: 875-84. PMID 18726893 DOI: 10.1002/Jcb.21889  0.772
2007 Eblen ST, Kumar NV, Weber MJ. Using genetically engineered kinases to screen for novel protein kinase substrates: phosphorylation of substrates in cell lysates with exogenous kinase. Csh Protocols. 2007: pdb.prot4639. PMID 21357058 DOI: 10.1101/Pdb.Prot4639  0.52
2007 Eblen ST, Kumar NV, Weber MJ. Using genetically engineered kinases to screen for novel protein kinase substrates: phosphorylation of kinase-associated substrates. Csh Protocols. 2007: pdb.prot4638. PMID 21357057 DOI: 10.1101/Pdb.Prot4638  0.485
2007 Eblen ST, Kumar NV, Weber MJ. Using Genetically Engineered Kinases to Screen for Novel Protein Kinase Substrates: Generation of [{gamma}-32P]ATP Analog from ADP Analog. Csh Protocols. 2007: pdb.prot4637. PMID 21357056 DOI: 10.1101/Pdb.Prot4637  0.352
2007 Eblen ST, Kumar NV, Weber MJ. Using Genetically Engineered Kinases to Screen for Novel Protein Kinase Substrates: Identification of a Mutant Kinase/ATP Analog Pair. Csh Protocols. 2007: pdb.prot4636. PMID 21357055 DOI: 10.1101/Pdb.Prot4636  0.452
2007 Park ER, Eblen ST, Catling AD. MEK1 activation by PAK: a novel mechanism. Cellular Signalling. 19: 1488-96. PMID 17314031 DOI: 10.1016/J.Cellsig.2007.01.018  0.479
2006 Gioeli D, Black BE, Gordon V, Spencer A, Kesler CT, Eblen ST, Paschal BM, Weber MJ. Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization. Molecular Endocrinology (Baltimore, Md.). 20: 503-15. PMID 16282370 DOI: 10.1210/Me.2005-0351  0.481
2005 Sharma C, Vomastek T, Tarcsafalvi A, Catling AD, Schaeffer HJ, Eblen ST, Weber MJ. MEK partner 1 (MP1): regulation of oligomerization in MAP kinase signaling. Journal of Cellular Biochemistry. 94: 708-19. PMID 15547943 DOI: 10.1002/Jcb.20344  0.443
2004 Kumar NV, Eblen ST, Weber MJ. Identifying specific kinase substrates through engineered kinases and ATP analogs. Methods (San Diego, Calif.). 32: 389-97. PMID 15003601 DOI: 10.1016/J.Ymeth.2003.10.002  0.481
2004 Eblen ST, Slack-Davis JK, Tarcsafalvi A, Parsons JT, Weber MJ, Catling AD. Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion. Molecular and Cellular Biology. 24: 2308-17. PMID 14993270 DOI: 10.1128/Mcb.24.6.2308-2317.2004  0.494
2003 Slack-Davis JK, Eblen ST, Zecevic M, Boerner SA, Tarcsafalvi A, Diaz HB, Marshall MS, Weber MJ, Parsons JT, Catling AD. PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation. The Journal of Cell Biology. 162: 281-91. PMID 12876277 DOI: 10.1083/Jcb.200212141  0.475
2003 Eblen ST, Kumar NV, Shah K, Henderson MJ, Watts CK, Shokat KM, Weber MJ. Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs. The Journal of Biological Chemistry. 278: 14926-35. PMID 12594221 DOI: 10.1074/Jbc.M300485200  0.523
2002 Eblen ST, Slack JK, Weber MJ, Catling AD. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. Molecular and Cellular Biology. 22: 6023-33. PMID 12167697 DOI: 10.1128/Mcb.22.17.6023-6033.2002  0.504
2001 Catling AD, Eblen ST, Schaeffer HJ, Weber MJ. Scaffold protein regulation of mitogen-activated protein kinase cascade. Methods in Enzymology. 332: 368-87. PMID 11305112 DOI: 10.1016/S0076-6879(01)32216-4  0.439
2001 Eblen ST, Catling AD, Assanah MC, Weber MJ. Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2. Molecular and Cellular Biology. 21: 249-59. PMID 11113199 DOI: 10.1128/Mcb.21.1.249-259.2001  0.502
1999 Slack JK, Catling AD, Eblen ST, Weber MJ, Parsons JT. c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration. The Journal of Biological Chemistry. 274: 27177-84. PMID 10480934 DOI: 10.1074/jbc.274.38.27177  0.324
1998 Zecevic M, Catling AD, Eblen ST, Renzi L, Hittle JC, Yen TJ, Gorbsky GJ, Weber MJ. Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E. The Journal of Cell Biology. 142: 1547-58. PMID 9744883 DOI: 10.1083/Jcb.142.6.1547  0.427
1998 Schaeffer HJ, Catling AD, Eblen ST, Collier LS, Krauss A, Weber MJ. MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science (New York, N.Y.). 281: 1668-71. PMID 9733512 DOI: 10.1126/Science.281.5383.1668  0.493
1995 Fautsch MP, Eblen ST, Anders RA, Burnette RJ, Leof EB. Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor-beta 1 in murine mammary epithelial cells. Journal of Cellular Biochemistry. 58: 517-26. PMID 7593274 DOI: 10.1002/Jcb.240580415  0.397
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