Dhara N. Amin, Ph.D. - Publications

Affiliations: 
2003 Yale University, New Haven, CT 
Area:
Molecular Biology, Oncology

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Campbell MR, Zhang H, Ziaee S, Ruiz-Saenz A, Gulizia N, Oeffinger J, Amin DN, Ahuja D, Moasser MM, Park CC. Effective treatment of HER2-amplified breast cancer by targeting HER3 and β1 integrin. Breast Cancer Research and Treatment. PMID 26860947 DOI: 10.1007/S10549-016-3698-Y  0.466
2015 Amin DN, Ruiz-Saenz A, Gulizia N, Moasser MM. Chemical probing of HER2-amplified cancer cells identifies TORC2 as a particularly effective secondary target for combination with lapatinib. Oncotarget. 6: 41123-33. PMID 26516700 DOI: 10.18632/Oncotarget.5660  0.488
2015 Amin DN, Ahuja D, Yaswen P, Moasser MM. A TORC2-Akt Feed-Forward Topology Underlies HER3 Resiliency in HER2-Amplified Cancers. Molecular Cancer Therapeutics. 14: 2805-17. PMID 26438156 DOI: 10.1158/1535-7163.Mct-15-0403  0.463
2014 Park CC, Amin D, Zhang H, Moasser M. Abstract 5438: Resistance to β1 integrin inhibition in HER2 amplified cancers is mediated by HER3 Cancer Research. 74: 5438-5438. DOI: 10.1158/1538-7445.Am2014-5438  0.383
2013 Amin DN, Ahuja D, Ducker GS, Yaswen P, Shokat K, Moasser M. Abstract 3043: Akt-mTorc2 signaling underlies cellular addiction to HER3 signaling in HER2-amplified cancers. Cancer Research. 73: 3043-3043. DOI: 10.1158/1538-7445.Am2013-3043  0.517
2012 Amin DN, Sergina N, Lim L, Goga A, Moasser MM. HER3 signalling is regulated through a multitude of redundant mechanisms in HER2-driven tumour cells. The Biochemical Journal. 447: 417-25. PMID 22853430 DOI: 10.1042/Bj20120724  0.479
2010 Amin DN, Campbell MR, Moasser MM. The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics. Seminars in Cell & Developmental Biology. 21: 944-50. PMID 20816829 DOI: 10.1016/J.Semcdb.2010.08.007  0.454
2010 Coma S, Amin DN, Shimizu A, Lasorella A, Iavarone A, Klagsbrun M. Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F. Cancer Research. 70: 3823-32. PMID 20388805 DOI: 10.1158/0008-5472.Can-09-3048  0.401
2010 Amin DN, Sergina N, Ahuja D, McMahon M, Blair JA, Wang D, Hann B, Koch KM, Shokat KM, Moasser MM. Resiliency and vulnerability in the HER2-HER3 tumorigenic driver. Science Translational Medicine. 2: 16ra7. PMID 20371474 DOI: 10.1126/Scitranslmed.3000389  0.543
2010 Campbell MR, Amin D, Moasser MM. HER3 Comes of Age: New Insights into Its Functions and Role in Signaling, Tumor Biology, and Cancer Therapy Clinical Cancer Research. 16: 1373-1383. PMID 20179223 DOI: 10.1158/1078-0432.Ccr-09-1218  0.529
2010 Amin DN, Sergina N, Ahuja D, McMahon M, Wang D, Hann B, Shokat K, Moasser MM. Abstract 1653: Highly effective treatment of HER2-amplified breast cancers through the complete inactivation of the HER2-HER3 tumorigenic driver Cancer Research. 70: 1653-1653. DOI: 10.1158/1538-7445.Am10-1653  0.527
2008 Amin DN, Bielenberg DR, Lifshits E, Heymach JV, Klagsbrun M. Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells. Microvascular Research. 76: 15-22. PMID 18440031 DOI: 10.1016/J.Mvr.2008.01.002  0.481
2006 Amin DN, Hida K, Bielenberg DR, Klagsbrun M. Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors. Cancer Research. 66: 2173-80. PMID 16489018 DOI: 10.1158/0008-5472.Can-05-3387  0.495
2005 Amin DN, Tuck D, Stern DF. Neuregulin-regulated gene expression in mammary carcinoma cells. Experimental Cell Research. 309: 12-23. PMID 15963498 DOI: 10.1016/J.Yexcr.2005.04.034  0.573
2004 Hida K, Hida Y, Amin DN, Flint AF, Panigrahy D, Morton CC, Klagsbrun M. Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Research. 64: 8249-55. PMID 15548691 DOI: 10.1158/0008-5472.Can-04-1567  0.345
2004 Amin DN, Perkins AS, Stern DF. Gene expression profiling of ErbB receptor and ligand-dependent transcription. Oncogene. 23: 1428-38. PMID 14973552 DOI: 10.1038/Sj.Onc.1207257  0.564
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