| Year |
Citation |
Score |
| 2010 |
Barrila J, Gabelli SB, Bacha U, Amzel LM, Freire E. Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) . Biochemistry. 49: 4308-17. PMID 20420403 DOI: 10.1021/Bi1002585 |
0.728 |
|
| 2009 |
Regnier T, Sarma D, Hidaka K, Bacha U, Freire E, Hayashi Y, Kiso Y. New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 2722-7. PMID 19362479 DOI: 10.1016/J.Bmcl.2009.03.118 |
0.611 |
|
| 2008 |
Bacha U, Barrila J, Gabelli SB, Kiso Y, Mario Amzel L, Freire E. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chemical Biology & Drug Design. 72: 34-49. PMID 18611220 DOI: 10.1111/J.1747-0285.2008.00679.X |
0.732 |
|
| 2008 |
Brower ET, Bacha UM, Kawasaki Y, Freire E. Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use. Chemical Biology & Drug Design. 71: 298-305. PMID 18312292 DOI: 10.1111/J.1747-0285.2008.00647.X |
0.661 |
|
| 2006 |
Sydnes MO, Hayashi Y, Sharma VK, Hamada T, Bacha U, Barrila J, Freire E, Kiso Y. Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors. Tetrahedron. 62: 8601-8609. PMID 32287416 DOI: 10.1016/J.Tet.2006.06.052 |
0.693 |
|
| 2006 |
Barrila J, Bacha U, Freire E. Long-range cooperative interactions modulate dimerization in SARS 3CLpro. Biochemistry. 45: 14908-16. PMID 17154528 DOI: 10.1021/Bi0616302 |
0.734 |
|
| 2004 |
Bacha U, Barrila J, Velazquez-Campoy A, Leavitt SA, Freire E. Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro. Biochemistry. 43: 4906-12. PMID 15109248 DOI: 10.1021/Bi0361766 |
0.674 |
|
| 2003 |
Velázquez-Campoy A, Vega S, Fleming E, Bacha U, Sayed Y, Dirr HW, Freire E. Protease inhibition in African subtypes of HIV-1. Aids Reviews. 5: 165-71. PMID 14598565 |
0.533 |
|
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