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Nirmal D. Pugh, Ph.D. - Publications

Affiliations: 
2001 The University of Mississippi, USA 
Area:
Pharmacology, Organic Chemistry, Immunology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Haron MH, Zhang J, Chittiboyina AG, Khan IA, Pugh ND. Validation of a Toll-like Receptor (TLR)2/TLR1 Activation Assay for Biological Standardization of / Immune-Enhancing Potency. Journal of Dietary Supplements. 1-13. PMID 37794652 DOI: 10.1080/19390211.2023.2263566  0.349
2023 Li Y, Ji N, Wang M, Pugh ND, Khan IA, Tan C. Immulina as an Immunostimulatory Supplement: Formulation and Pharmacological Studies. Planta Medica. PMID 37647915 DOI: 10.1055/a-2156-4653  0.369
2019 Zhang J, Tyler HL, Haron MH, Jackson CR, Pasco DS, Pugh ND. Macrophage activation by edible mushrooms is due to the collaborative interaction of toll-like receptor agonists and dectin-1b activating beta glucans derived from colonizing microorganisms. Food & Function. PMID 31701990 DOI: 10.1039/C9Fo01707K  0.709
2019 Haron MH, Tyler HL, Chandra S, Moraes RM, Jackson CR, Pugh ND, Pasco DS. Plant microbiome-dependent immune enhancing action of Echinacea purpurea is enhanced by soil organic matter content. Scientific Reports. 9: 136. PMID 30644442 DOI: 10.1038/S41598-018-36907-X  0.679
2016 Tyler HL, Haron MH, Pugh ND, Zhang J, Jackson CR, Pasco DS. Bacterial components are the major contributors to the macrophage stimulating activity exhibited by extracts of common edible mushrooms. Food & Function. PMID 27711863 DOI: 10.1039/C6Fo00562D  0.742
2016 Haron MH, Tyler HL, Pugh ND, Moraes RM, Maddox VL, Jackson CR, Pasco DS. Activities and Prevalence of Proteobacteria Members Colonizing Echinacea purpurea Fully Account for Macrophage Activation Exhibited by Extracts of This Botanical. Planta Medica. PMID 27286330 DOI: 10.1055/S-0042-108590  0.721
2016 Zhang J, Howard X, Gul W, Pasco D, ElSohly M, Pugh N. In Vitro Bioassays For Standardization Of Immune Enhancing Dietary Supplements Planta Medica. 82. DOI: 10.1055/S-0036-1578701  0.645
2015 Pugh ND, Edwall D, Lindmark L, Kousoulas KG, Iyer AV, Haron MH, Pasco DS. Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infection. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 22: 271-6. PMID 25765832 DOI: 10.1016/J.Phymed.2014.12.006  0.653
2015 Haron M, Tyler H, Pugh N, Jackson C, Moraes R, Maddox V, Pasco D. In vitro macrophage activation exhibited by Echinacea purpurea aerial extracts is equivalent to the total activity exhibited by the endophytic bacteria associated with these plant samples Planta Medica. 81. DOI: 10.1055/S-0035-1545172  0.711
2015 Haron M, Tyler H, Pugh N, Jackson C, Chandra S, Moraes R, Pasco D. Increase in soil organic matter content enhances bacterial endophyte-dependent in vitro macrophage activity exhibited by Echinacea purpurea root material Planta Medica. 81. DOI: 10.1055/S-0035-1545171  0.667
2014 Yang Y, Inatsuka C, Gad E, Disis ML, Standish LJ, Pugh N, Pasco DS, Lu H. Protein-bound polysaccharide-K induces IL-1β via TLR2 and NLRP3 inflammasome activation. Innate Immunity. 20: 857-66. PMID 24323452 DOI: 10.1177/1753425913513814  0.649
2014 Haron M, Tyler H, Pugh N, Jackson C, Chandra S, Moraes R, Maddox V, Pasco D. Immune enhancing Echinacea bacterial endophytes Planta Medica. 80. DOI: 10.1055/S-0034-1382710  0.667
2014 Haron M, Tyler H, Pugh N, Jackson C, Pasco D. In vitro macrophage activation by edible mushroom extracts varies considerably and is highly correlated to bacterial LPS content Planta Medica. 80. DOI: 10.1055/S-0034-1382707  0.719
2014 Pugh N, Edwall D, Lindmark L, Kousoulas K, Iyer A, Pasco D. Protective effect of orally administered Spirulina braun-type lipoproteins against influenza A (H1N1) virus infection in mice Planta Medica. 80. DOI: 10.1055/S-0034-1382706  0.67
2013 Pugh ND, Jackson CR, Pasco DS. Total bacterial load within Echinacea purpurea, determined using a new PCR-based quantification method, is correlated with LPS levels and in vitro macrophage activity. Planta Medica. 79: 9-14. PMID 23212786 DOI: 10.1055/S-0032-1328023  0.724
2013 Pasco D, Pugh N, Balachandran P, Jackson C. Immune Enhancing Bacterial Endophytic Components in Echinacea and Other Botanicals Planta Medica. 79. DOI: 10.1055/S-0033-1336429  0.736
2011 Moraes RM, Lata H, Sumyanto J, Pereira AMS, Bertoni BW, Joshi VC, Pugh ND, Khan IA, Pasco DS. Characterization and pharmacological properties of in vitro propagated clones of Echinacea tennesseensis (Beadle) Small Plant Cell, Tissue and Organ Culture. 106: 309-315. DOI: 10.1007/S11240-011-9922-X  0.698
2010 Nielsen CH, Balachandran P, Christensen O, Pugh ND, Tamta H, Sufka KJ, Wu X, Walsted A, Schjørring-Thyssen M, Enevold C, Pasco DS. Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins. Planta Medica. 76: 1802-8. PMID 20560112 DOI: 10.1055/S-0030-1250043  0.644
2009 Balachandran P, Pugh N, Tamta H, Sufka K, Wu X, Pasco D. Enhancement of Natural Killer Cell Activity and Phagocytosis in Healthy Subjects by Immulina, a Spirulina Extract Enriched for Braun Type Lipoproteins Planta Medica. 75. DOI: 10.1055/S-2009-1216531  0.69
2009 Tamta H, Pugh ND, Balachandran P, Moraes RM, Sumiyanto J, Pasco DS. Variability of In Vitro Macrophage Activation by Commercially Diverse Bulk Echinacea Plant Material is Due Predominantly to Bacterial Lipoproteins and Lipopolysaccharides Planta Medica. 75. DOI: 10.1055/S-2009-1216530  0.696
2009 Moraes R, Sumiyanto J, Lata H, Tamta H, Pugh N, Wu X, Joshi V, Khan I, Pasco D. In vitro Monocyte Activity of Echinacea purpurea: Endophytic Bacteria is Affected by the Host's Genetic Diversity and Harvest Timing Planta Medica. 75. DOI: 10.1055/S-2009-1216441  0.659
2008 Tamta H, Pugh ND, Balachandran P, Moraes R, Sumiyanto J, Pasco DS. Variability in in vitro macrophage activation by commercially diverse bulk echinacea plant material is predominantly due to bacterial lipoproteins and lipopolysaccharides. Journal of Agricultural and Food Chemistry. 56: 10552-6. PMID 18942831 DOI: 10.1021/Jf8023722  0.744
2008 Pugh ND, Tamta H, Balachandran P, Wu X, Howell J, Dayan FE, Pasco DS. The majority of in vitro macrophage activation exhibited by extracts of some immune enhancing botanicals is due to bacterial lipoproteins and lipopolysaccharides. International Immunopharmacology. 8: 1023-32. PMID 18486914 DOI: 10.1016/J.Intimp.2008.03.007  0.75
2006 Balachandran P, Pugh ND, Ma G, Pasco DS. Toll-like receptor 2-dependent activation of monocytes by Spirulina polysaccharide and its immune enhancing action in mice. International Immunopharmacology. 6: 1808-14. PMID 17052671 DOI: 10.1016/J.Intimp.2006.08.001  0.717
2006 Grzanna R, Polotsky A, Phan PV, Pugh N, Pasco D, Frondoza CG. Immolina, a high-molecular-weight polysaccharide fraction of Spirulina, enhances chemokine expression in human monocytic THP-1 cells. Journal of Alternative and Complementary Medicine (New York, N.Y.). 12: 429-35. PMID 16813506 DOI: 10.1089/Acm.2006.12.429  0.679
2005 Pugh ND, Balachandran P, Lata H, Dayan FE, Joshi V, Bedir E, Makino T, Moraes R, Khan I, Pasco DS. Melanin: dietary mucosal immune modulator from Echinacea and other botanical supplements. International Immunopharmacology. 5: 637-47. PMID 15710333 DOI: 10.1016/J.Intimp.2004.12.011  0.712
2002 Duncan CJ, Pugh N, Pasco DS, Ross SA. Isolation of a galactomannan that enhances macrophage activation from the edible fungus Morchella esculenta. Journal of Agricultural and Food Chemistry. 50: 5683-5. PMID 12236698 DOI: 10.1021/Jf020267C  0.71
2001 Pugh N, Ross SA, Eisohly HN, Eisohly MA, Pasco DS. Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, Aphanizomenon flos-aquae and Chlorella pyrenoidosa Planta Medica. 67: 737-742. PMID 11731916 DOI: 10.1055/S-2001-18358  0.698
2001 Pugh N, Khan IA, Moraes RM, Pasco DS. Podophyllotoxin lignans enhance IL-1beta but suppress TNF-alpha mRNA expression in LPS-treated monocytes. Immunopharmacology and Immunotoxicology. 23: 83-95. PMID 11322652 DOI: 10.1081/Iph-100102570  0.654
2001 Pugh N, Ross SA, ElSohly MA, Pasco DS. Characterization of aloeride, a new high-molecular-weight polysaccharide from Aloe vera with potent immunostimulatory activity Journal of Agricultural and Food Chemistry. 49: 1030-1034. PMID 11262067 DOI: 10.1021/Jf001036D  0.716
2000 Bedir E, Pugh N, Calis I, Pasco DS, Khan IA. Immunostimulatory effects of cycloartane-type triterpene glycosides from Astragalus species Biological and Pharmaceutical Bulletin. 23: 834-837. PMID 10919362 DOI: 10.1248/Bpb.23.834  0.675
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