| Year |
Citation |
Score |
| 2020 |
Mallick P, Song G, Efremenko AY, Pendse SN, Creek MR, Osimitz TG, Hines RN, Hinderliter P, Clewell HJ, Lake BG, Yoon M, Moreau M. Physiologically based pharmacokinetic (PBPK) modelling in risk assessment: Case study with pyrethroids. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32421774 DOI: 10.1093/Toxsci/Kfaa070 |
0.319 |
|
| 2019 |
Mallick P, Moreau M, Song G, Efremenko AY, Pendse SN, Creek MR, Osimitz TG, Hines RN, Hinderliter P, Clewell HJ, Lake BG, Yoon M. Development and Application of a Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31593217 DOI: 10.1093/Toxsci/Kfz211 |
0.362 |
|
| 2019 |
Matlock MK, Tambe A, Elliott-Higgins J, Hines RN, Miller GP, Swamidass SJ. A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes. Chemical Research in Toxicology. PMID 31304741 DOI: 10.1021/Acs.Chemrestox.9B00223 |
0.362 |
|
| 2019 |
Dubaisi S, Caruso JA, Gaedigk R, Vyhlidal CA, Smith PC, Hines RN, Kocarek TA, Runge-Morris M. Developmental Expression of the Cytosolic Sulfotransferases in Human Liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30885913 DOI: 10.1124/Dmd.119.086363 |
0.471 |
|
| 2019 |
Hines RN, Klick DE, Koukouritaki SB, Gerner EW, Thompson P, Jr MFL. Flavin-Containing monooxygenases Drug Metabolism Reviews. 41: 17-18. DOI: 10.2210/Pdb5Z8T/Pdb |
0.741 |
|
| 2018 |
Kenyon EM, Lipscomb JC, Pegram RA, George BJ, Hines RN. The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study using Bromodichloromethane (BDCM). Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30252107 DOI: 10.1093/Toxsci/Kfy236 |
0.339 |
|
| 2017 |
Song G, Sun X, Hines RN, McCarver DG, Lake BG, Osimitz TG, Creek MR, Clewell HJ, Yoon M. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28228413 DOI: 10.1124/Dmd.116.074583 |
0.436 |
|
| 2016 |
Thomson MM, Hines RN, Schuetz EG, Meibohm B. Expression Patterns of OATP 1B1 and OATP 1B3 Protein in Human Pediatric Liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27098745 DOI: 10.1124/Dmd.115.069252 |
0.384 |
|
| 2016 |
Giebel NL, Shadley JD, McCarver DG, Dorko K, Gramignoli R, Strom SC, Yan K, Simpson PM, Hines RN. Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26921389 DOI: 10.1124/Dmd.116.069344 |
0.399 |
|
| 2016 |
Hines RN, Simpson PM, McCarver DG. Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 959-66. PMID 26825642 DOI: 10.1124/Dmd.115.068957 |
0.391 |
|
| 2015 |
McCullough SD, Bowers EC, On DM, Morgan DS, Dailey LA, Hines RN, Devlin RB, Diaz-Sanchez D. Baseline Chromatin Modification Levels May Predict Inter-Individual Variability in Ozone-induced Gene Expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26719369 DOI: 10.1093/Toxsci/Kfv324 |
0.318 |
|
| 2015 |
Rudraiah S, Gu X, Hines RN, Manautou JE. Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 26616280 DOI: 10.1016/J.Tiv.2015.11.016 |
0.441 |
|
| 2015 |
Sethi PK, White CA, Cummings BS, Hines RN, Muralidhara S, Bruckner JV. Ontogeny of Plasma Proteins, Albumin and Binding of Diazepam, Cyclosporine and Deltamethrin. Pediatric Research. PMID 26571224 DOI: 10.1038/Pr.2015.237 |
0.34 |
|
| 2014 |
Divakaran K, Hines RN, McCarver DG. Human hepatic UGT2B15 developmental expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 292-9. PMID 24980262 DOI: 10.1093/Toxsci/Kfu126 |
0.433 |
|
| 2014 |
Rudraiah S, Rohrer PR, Gurevich I, Goedken MJ, Rasmussen T, Hines RN, Manautou JE. Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 263-77. PMID 24973094 DOI: 10.1093/Toxsci/Kfu124 |
0.408 |
|
| 2013 |
Sharma S, Ellis EC, Gramignoli R, Dorko K, Tahan V, Hansel M, Mattison DR, Caritis SN, Hines RN, Venkataramanan R, Strom SC. Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 296-304. PMID 23129211 DOI: 10.1124/Dmd.112.044891 |
0.363 |
|
| 2012 |
Hines RN. Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children. International Journal of Pharmaceutics. 452: 3-7. PMID 22766445 DOI: 10.1016/J.Ijpharm.2012.05.079 |
0.392 |
|
| 2012 |
Li W, Gu Y, James MO, Hines RN, Simpson P, Langaee T, Stacpoole PW. Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 232-9. PMID 22028318 DOI: 10.1124/Dmd.111.041533 |
0.445 |
|
| 2011 |
Marongiu F, Gramignoli R, Dorko K, Miki T, Ranade AR, Paola Serra M, Doratiotto S, Sini M, Sharma S, Mitamura K, Sellaro TL, Tahan V, Skvorak KJ, Ellis EC, Badylak SF, ... ... Hines R, et al. Hepatic differentiation of amniotic epithelial cells. Hepatology (Baltimore, Md.). 53: 1719-29. PMID 21374689 DOI: 10.1002/Hep.24255 |
0.409 |
|
| 2009 |
Croom EL, Stevens JC, Hines RN, Wallace AD, Hodgson E. Human hepatic CYP2B6 developmental expression: the impact of age and genotype. Biochemical Pharmacology. 78: 184-90. PMID 19464434 DOI: 10.1016/J.Bcp.2009.03.029 |
0.408 |
|
| 2008 |
Klick DE, Shadley JD, Hines RN. Differential regulation of human hepatic flavin containing monooxygenase 3 (FMO3) by CCAAT/enhancer-binding protein beta (C/EBPbeta) liver inhibitory and liver activating proteins. Biochemical Pharmacology. 76: 268-78. PMID 18555208 DOI: 10.1016/J.Bcp.2008.05.002 |
0.735 |
|
| 2008 |
Stevens JC, Marsh SA, Zaya MJ, Regina KJ, Divakaran K, Le M, Hines RN. Developmental changes in human liver CYP2D6 expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1587-93. PMID 18474679 DOI: 10.1124/Dmd.108.021873 |
0.411 |
|
| 2008 |
Hines RN, Koukouritaki SB, Poch MT, Stephens MC. Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition. Drug Metabolism Reviews. 40: 263-301. PMID 18464046 DOI: 10.1080/03602530801952682 |
0.399 |
|
| 2008 |
Hines RN. The ontogeny of drug metabolism enzymes and implications for adverse drug events. Pharmacology & Therapeutics. 118: 250-67. PMID 18406467 DOI: 10.1016/J.Pharmthera.2008.02.005 |
0.397 |
|
| 2008 |
Kramer MA, Rettie AE, Rieder MJ, Cabacungan ET, Hines RN. Novel CYP2C9 promoter variants and assessment of their impact on gene expression. Molecular Pharmacology. 73: 1751-60. PMID 18310303 DOI: 10.1124/Mol.107.044149 |
0.357 |
|
| 2007 |
Hines RN. Ontogeny of human hepatic cytochromes P450. Journal of Biochemical and Molecular Toxicology. 21: 169-75. PMID 17936930 DOI: 10.1002/Jbt.20179 |
0.437 |
|
| 2007 |
Klick DE, Hines RN. Mechanisms regulating human FMO3 transcription. Drug Metabolism Reviews. 39: 419-42. PMID 17786630 DOI: 10.1080/03602530701498612 |
0.744 |
|
| 2007 |
Shadley JD, Divakaran K, Munson K, Hines RN, Douglas K, McCarver DG. Identification and functional analysis of a novel human CYP2E1 far upstream enhancer. Molecular Pharmacology. 71: 1630-9. PMID 17353354 DOI: 10.1124/Mol.106.031302 |
0.401 |
|
| 2007 |
Koukouritaki SB, Poch MT, Henderson MC, Siddens LK, Krueger SK, VanDyke JE, Williams DE, Pajewski NM, Wang T, Hines RN. Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants. The Journal of Pharmacology and Experimental Therapeutics. 320: 266-73. PMID 17050781 DOI: 10.1124/Jpet.106.112268 |
0.305 |
|
| 2007 |
Kramer MA, Rettie AE, Rieder MJ, Hines RN. Novel Hispanic American
CYP2C9
Genetic Variants and Assessment of Their Impact on Gene Expression The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A415 |
0.309 |
|
| 2006 |
Zaya MJ, Hines RN, Stevens JC. Epirubicin glucuronidation and UGT2B7 developmental expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 2097-101. PMID 16985101 DOI: 10.1124/Dmd.106.011387 |
0.356 |
|
| 2006 |
Hines RN. Developmental and tissue-specific expression of human flavin-containing monooxygenases 1 and 3. Expert Opinion On Drug Metabolism & Toxicology. 2: 41-9. PMID 16863467 DOI: 10.1517/17425255.2.1.41 |
0.463 |
|
| 2006 |
Vyas PM, Roychowdhury S, Khan FD, Prisinzano TE, Lamba J, Schuetz EG, Blaisdell J, Goldstein JA, Munson KL, Hines RN, Svensson CK. Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: I. Expression and role of cytochromes P450. The Journal of Pharmacology and Experimental Therapeutics. 319: 488-96. PMID 16857728 DOI: 10.1124/Jpet.106.105858 |
0.418 |
|
| 2006 |
Vyas PM, Roychowdhury S, Koukouritaki SB, Hines RN, Krueger SK, Williams DE, Nauseef WM, Svensson CK. Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases. The Journal of Pharmacology and Experimental Therapeutics. 319: 497-505. PMID 16857727 DOI: 10.1124/Jpet.106.105874 |
0.455 |
|
| 2006 |
Yang F, Tong X, McCarver DG, Hines RN, Beard DA. Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model. Journal of Pharmacokinetics and Pharmacodynamics. 33: 485-518. PMID 16758333 DOI: 10.1007/S10928-006-9018-0 |
0.312 |
|
| 2006 |
Krueger SK, Vandyke JE, Williams DE, Hines RN. The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines. Drug Metabolism Reviews. 38: 139-47. PMID 16684653 DOI: 10.1080/03602530600569919 |
0.344 |
|
| 2006 |
Nong A, McCarver DG, Hines RN, Krishnan K. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene. Toxicology and Applied Pharmacology. 214: 78-87. PMID 16464483 DOI: 10.1016/J.Taap.2005.12.001 |
0.376 |
|
| 2006 |
Duanmu Z, Weckle A, Koukouritaki SB, Hines RN, Falany JL, Falany CN, Kocarek TA, Runge-Morris M. Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. The Journal of Pharmacology and Experimental Therapeutics. 316: 1310-7. PMID 16339912 DOI: 10.1124/Jpet.105.093633 |
0.474 |
|
| 2005 |
Koukouritaki SB, Hines RN. Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development. Pharmacogenomics. 6: 807-22. PMID 16296944 DOI: 10.2217/14622416.6.8.807 |
0.362 |
|
| 2005 |
Poch MT, Cutler NS, Yost GS, Hines RN. Molecular mechanisms regulating human CYP4B1 lung-selective expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1174-84. PMID 15900016 DOI: 10.1124/Dmd.105.004523 |
0.4 |
|
| 2005 |
Krueger SK, Siddens LK, Henderson MC, Andreasen EA, Tanguay RL, Pereira CB, Cabacungan ET, Hines RN, Ardlie KG, Williams DE. Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics. Pharmacogenetics and Genomics. 15: 245-56. PMID 15864117 DOI: 10.1097/01213011-200504000-00008 |
0.303 |
|
| 2005 |
Wan J, Carr BA, Cutler NS, Lanza DL, Hines RN, Yost GS. Sp1 and Sp3 regulate basal transcription of the human CYP2F1 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1244-53. PMID 15860659 DOI: 10.1124/Dmd.105.004069 |
0.369 |
|
| 2005 |
Koukouritaki SB, Poch MT, Cabacungan ET, McCarver DG, Hines RN. Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants. Molecular Pharmacology. 68: 383-92. PMID 15858076 DOI: 10.1124/Mol.105.012062 |
0.37 |
|
| 2004 |
Poch MT, Al-Kassim L, Smolinski SM, Hines RN. Two distinct classes of CCAAT box elements that bind nuclear factor-Y/alpha-actinin-4: potential role in human CYP1A1 regulation. Toxicology and Applied Pharmacology. 199: 239-50. PMID 15364540 DOI: 10.1016/J.Taap.2003.12.023 |
0.396 |
|
| 2004 |
Krueger SK, Siddens LK, Martin SR, Yu Z, Pereira CB, Cabacungan ET, Hines RN, Ardlie KG, Raucy JL, Williams DE. Differences in FMO2*1 allelic frequency between Hispanics of Puerto Rican and Mexican descent. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1337-40. PMID 15355885 DOI: 10.1124/Dmd.104.001099 |
0.341 |
|
| 2004 |
Koukouritaki SB, Manro JR, Marsh SA, Stevens JC, Rettie AE, McCarver DG, Hines RN. Developmental expression of human hepatic CYP2C9 and CYP2C19. The Journal of Pharmacology and Experimental Therapeutics. 308: 965-74. PMID 14634042 DOI: 10.1124/Jpet.103.060137 |
0.43 |
|
| 2003 |
Johnsrud EK, Koukouritaki SB, Divakaran K, Brunengraber LL, Hines RN, McCarver DG. Human hepatic CYP2E1 expression during development. The Journal of Pharmacology and Experimental Therapeutics. 307: 402-7. PMID 14500779 DOI: 10.1124/Jpet.103.053124 |
0.38 |
|
| 2003 |
Stevens JC, Hines RN, Gu C, Koukouritaki SB, Manro JR, Tandler PJ, Zaya MJ. Developmental expression of the major human hepatic CYP3A enzymes. The Journal of Pharmacology and Experimental Therapeutics. 307: 573-82. PMID 12975492 DOI: 10.1124/Jpet.103.054841 |
0.451 |
|
| 2003 |
Hines RN, Luo Z, Hopp KA, Cabacungan ET, Koukouritaki SB, McCarver DG. Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6). The Journal of Pharmacology and Experimental Therapeutics. 306: 1210-8. PMID 12829732 DOI: 10.1124/Jpet.103.053686 |
0.402 |
|
| 2003 |
Cashman JR, Camp K, Fakharzadeh SS, Fennessey PV, Hines RN, Mamer OA, Mitchell SC, Nguyen GP, Schlenk D, Smith RL, Tjoa SS, Williams DE, Yannicelli S. Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria. Current Drug Metabolism. 4: 151-70. PMID 12678693 DOI: 10.2174/1389200033489505 |
0.304 |
|
| 2003 |
Zheng YM, Henne KR, Charmley P, Kim RB, McCarver DG, Cabacungan ET, Hines RN, Rettie AE. Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis. Toxicology and Applied Pharmacology. 186: 119-26. PMID 12639503 DOI: 10.1016/S0041-008X(02)00028-5 |
0.373 |
|
| 2003 |
Carr BA, Wan J, Hines RN, Yost GS. Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif. The Journal of Biological Chemistry. 278: 15473-83. PMID 12598524 DOI: 10.1074/Jbc.M300319200 |
0.405 |
|
| 2002 |
Krueger SK, Williams DE, Yueh MF, Martin SR, Hines RN, Raucy JL, Dolphin CT, Shephard EA, Phillips IR. Genetic polymorphisms of flavin-containing monooxygenase (FMO). Drug Metabolism Reviews. 34: 523-32. PMID 12214664 DOI: 10.1081/Dmr-120005653 |
0.382 |
|
| 2002 |
Hines RN, Hopp KA, Franco J, Saeian K, Begun FP. Alternative processing of the human FMO6 gene renders transcripts incapable of encoding a functional flavin-containing monooxygenase. Molecular Pharmacology. 62: 320-5. PMID 12130684 DOI: 10.1124/Mol.62.2.320 |
0.416 |
|
| 2002 |
Koukouritaki SB, Simpson P, Yeung CK, Rettie AE, Hines RN. Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression. Pediatric Research. 51: 236-43. PMID 11809920 DOI: 10.1203/00006450-200202000-00018 |
0.442 |
|
| 2002 |
McCarver DG, Hines RN. The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 300: 361-6. PMID 11805192 DOI: 10.1124/Jpet.300.2.361 |
0.474 |
|
| 2002 |
Hines RN, McCarver DG. The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes. The Journal of Pharmacology and Experimental Therapeutics. 300: 355-60. PMID 11805191 DOI: 10.1124/Jpet.300.2.355 |
0.44 |
|
| 2001 |
Luo Z, Hines RN. Regulation of flavin-containing monooxygenase 1 expression by ying yang 1 and hepatic nuclear factors 1 and 4. Molecular Pharmacology. 60: 1421-30. PMID 11723251 DOI: 10.1124/Mol.60.6.1421 |
0.443 |
|
| 2001 |
Delescluse C, Ledirac N, Li R, Piechocki MP, Hines RN, Gidrol X, Rahmani R. Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells. Biochemical Pharmacology. 61: 399-407. PMID 11226373 DOI: 10.1016/S0006-2952(00)00562-1 |
0.427 |
|
| 2000 |
Whetstine JR, Yueh MF, Hopp KA, McCarver DG, Williams DE, Park CS, Kang JH, Cha YN, Dolphin CT, Shephard EA, Phillips IR, Hines RN. Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: Detection of expressed protein in African-Americans Toxicology and Applied Pharmacology. 168: 216-224. PMID 11042094 DOI: 10.1006/Taap.2000.9050 |
0.396 |
|
| 2000 |
Liu L, O'Hara DS, Cala SE, Poornima I, Hines RN, Marsh JD. Developmental regulation of the L-type calcium channel α1(C) subunit expression in heart Molecular and Cellular Biochemistry. 205: 101-109. PMID 10821427 DOI: 10.1023/A:1007013900827 |
0.34 |
|
| 2000 |
Ledirac N, Delescluse C, Lesca P, Piechocki MP, Hines RN, de Sousa G, Pralavorio M, Rahmani R. Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells. Toxicology and Applied Pharmacology. 164: 273-9. PMID 10799337 DOI: 10.1006/Taap.2000.8920 |
0.402 |
|
| 2000 |
Liu L, Fan QI, El-Zaru MR, Vanderpool K, Hines RN, Marsh JD. Regulation of DHP receptor expression by elements in the 5'-flanking sequence American Journal of Physiology - Heart and Circulatory Physiology. 278. PMID 10749709 DOI: 10.1152/Ajpheart.2000.278.4.H1153 |
0.36 |
|
| 1999 |
Larsen-Su S, Krueger SK, Yueh MF, Lee MY, Shehin SE, Hines RN, Williams DE. Flavin-containing monooxygenase isoform 2: Developmental expression in fetal and neonatal rabbit lung Journal of Biochemical and Molecular Toxicology. 13: 187-193. PMID 10098904 DOI: 10.1002/(Sici)1099-0461(1999)13:3/4<187::Aid-Jbt9>3.0.Co;2-6 |
0.375 |
|
| 1999 |
Linder MW, Falkner KC, Srinivasan G, Hines RN, Prough RA. Role of canonical glucocorticoid responsive elements in modulating expression of genes regulated by the arylhydrocarbon receptor. Drug Metabolism Reviews. 31: 247-71. PMID 10065375 DOI: 10.1081/Dmr-100101917 |
0.339 |
|
| 1998 |
Piechocki MP, Hines RN. Functional characterization of the human CYP1A1 negative regulatory element: modulation of Ah receptor mediated transcriptional activity. Carcinogenesis. 19: 771-80. PMID 9635862 DOI: 10.1093/Carcin/19.5.771 |
0.402 |
|
| 1998 |
Hines R, Smolinski S, Piechocki M. The human CYP1A1 negative regulatory element is able to modulate AH receptor mediated transcriptional activity Toxicology Letters. 95: 97-98. DOI: 10.1016/S0378-4274(98)80388-3 |
0.344 |
|
| 1997 |
Luo Z, Hines RN. Further characterization of the major and minor rabbit FMO1 promoters and identification of both positive and negative distal regulatory elements. Archives of Biochemistry and Biophysics. 346: 96-104. PMID 9328289 DOI: 10.1006/Abbi.1997.0287 |
0.361 |
|
| 1997 |
Luo Z, Hines RN. Identification of multiple rabbit flavin-containing monooxygenase form 1 (FMO1) gene promoters and observation of tissue-specific DNase I hypersensitive sites. Archives of Biochemistry and Biophysics. 336: 251-60. PMID 8954572 DOI: 10.1006/Abbi.1996.0555 |
0.379 |
|
| 1995 |
Schlenk D, Peters L, Shehin-Johnson S, Hines RN, Livingstone DR. Differential expression and activity of flavin-containing monooxygenases in euryhaline and stenohaline flatfishes indicates potential osmoregulatory role Comparative Biochemistry and Physiology. Part C: Comparative. 112: 179-186. PMID 8788588 DOI: 10.1016/0742-8413(95)02010-1 |
0.411 |
|
| 1995 |
Boucher PD, Hines RN. In vitro binding and functional studies comparing the human CYP1A1 negative regulatory element with the orthologous sequences from rodent genes. Carcinogenesis. 16: 383-92. PMID 7859371 DOI: 10.1093/Carcin/16.2.383 |
0.452 |
|
| 1995 |
Lee MY, Smiley S, Kadkhodayan S, Hines RN, Williams DE. Developmental regulation of flavin-containing monooxygenase (FMO) isoforms 1 and 2 in pregnant rabbit. Chemico-Biological Interactions. 96: 75-85. PMID 7720106 DOI: 10.1016/0009-2797(94)03584-U |
0.374 |
|
| 1995 |
Boucher PD, Piechocki MP, Hines RN. Partial characterization of the human CYP1A1 negatively acting transcription factor and mutational analysis of its cognate DNA recognition sequence. Molecular and Cellular Biology. 15: 5144-51. PMID 7651431 DOI: 10.1128/Mcb.15.9.5144 |
0.432 |
|
| 1995 |
Peters LD, Livingstone DR, Shenin-Johnson S, Hines RN, Schlenk D. Characterization of hepatic flavin monooxygenase from the marine teleost turbot (scophthalmus maximus L.) Xenobiotica. 25: 121-131. PMID 7618340 DOI: 10.3109/00498259509061838 |
0.363 |
|
| 1994 |
Lawton MP, Cashman JR, Cresteil T, Dolphin CT, Elfarra AA, Hines RN, Hodgson E, Kimura T, Ozols J, Phillips IR, Philpot RM, Poulsen LL, Rettie AE, Shephard EA, Williams DE, et al. A Nomenclature for the Mammalian Flavin-Containing Monooxygenase Gene Family Based on Amino Acid Sequence Identities Archives of Biochemistry and Biophysics. 308: 254-257. PMID 8311461 DOI: 10.1006/Abbi.1994.1035 |
0.326 |
|
| 1994 |
Thomsen JS, Wang X, Hines RN, Safe S. Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor. Carcinogenesis. 15: 933-7. PMID 8200098 DOI: 10.1093/Carcin/15.5.933 |
0.377 |
|
| 1994 |
Hines RN, Cashman JR, Philpot RM, Williams DE, Ziegler DM. The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. Toxicology and Applied Pharmacology. 125: 1-6. PMID 8128486 DOI: 10.1006/Taap.1994.1042 |
0.381 |
|
| 1993 |
States JC, Quan T, Hines RN, Novak RF, Runge-Morris M. Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector. Carcinogenesis. 14: 1643-9. PMID 8353849 DOI: 10.1093/Carcin/14.8.1643 |
0.353 |
|
| 1991 |
Thomsen JS, Nissen L, Stacey SN, Hines RN, Autrup H. Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors European Journal of Biochemistry. 197: 577-582. PMID 2029891 DOI: 10.1111/J.1432-1033.1991.Tb15946.X |
0.358 |
|
| 1990 |
Pasanen M, Haaparanta T, Sundin M, Sivonen P, Vakakangas K, Raunio H, Hines R, Jan-Åk Gustafsson, Pelkonen O. Immunochemical and molecular biological studies on human placental cigarette smoke-inducible cytochrome P-450-dependent monooxygenase activities Toxicology. 62: 175-187. PMID 1693794 DOI: 10.1016/0300-483X(90)90108-S |
0.342 |
|
| 1989 |
McLemore TL, Adelberg S, Czerwinski M, Hubbard WC, Yu SJ, Storeng R, Wood TG, Hines RN, Boyd MR. Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines. Journal of the National Cancer Institute. 81: 1787-94. PMID 2555530 DOI: 10.1093/Jnci/81.23.1787 |
0.36 |
|
| 1988 |
Hines RN, Mathis JM, Jacob CS. Identification of multiple regulatory elements on the human cytochrome P450IA1 gene Carcinogenesis. 9: 1599-1605. PMID 3409463 DOI: 10.1093/Carcin/9.9.1599 |
0.377 |
|
| 1988 |
Tiesman J, Meyer A, Hines RN, Rizzino A. Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells In Vitro Cellular &Amp; Developmental Biology. 24: 1209-1216. PMID 3209587 DOI: 10.1007/Bf02624192 |
0.305 |
|
| 1988 |
Pasanen M, Stacey S, Lykkesfeldt A, Briand P, Hines R, Autrup H. Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines Chemico-Biological Interactions. 66: 223-232. PMID 2456161 DOI: 10.1016/0009-2797(88)90073-7 |
0.315 |
|
| 1987 |
Iversen PL, Heiger WJ, Bresnick E, Hines RN. Structural details of the human cytochrome P-450c gene. Archives of Biochemistry and Biophysics. 256: 397-401. PMID 3606130 DOI: 10.1016/0003-9861(87)90460-7 |
0.361 |
|
| 1987 |
Houser WH, Cunningham CK, Hines RN, Schaeffer WI, Bresnick E. Interaction of the 4 S polycyclic aromatic hydrocarbon-binding protein with the cytochrome P-450c gene. Archives of Biochemistry and Biophysics. 259: 215-23. PMID 2825598 DOI: 10.1016/0003-9861(87)90488-7 |
0.388 |
|
| 1986 |
Houser WH, Hines RN, Bresnick E. Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression. Biochemistry. 24: 7839-45. PMID 4092041 DOI: 10.1021/Bi00347A050 |
0.383 |
|
| 1986 |
Iversen PL, Hines RN, Bresnick E. The molecular biology of the polycyclic aromatic hydrocarbon inducible cytochrome P-450; the past is prologue. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 4: 15-9. PMID 3790107 DOI: 10.1002/Bies.950040105 |
0.38 |
|
| 1986 |
Mathis JM, Prough RA, Hines RN, Bresnick E, Simpson ER. Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes Archives of Biochemistry and Biophysics. 246: 439-448. PMID 2870681 DOI: 10.1016/0003-9861(86)90490-X |
0.365 |
|
| 1985 |
Foldes RL, Hines RN, Ho KL, Shen ML, Nagel KB, Bresnick E. 3-Methylcholanthrene-induced expression of the cytochrome P-450c gene. Archives of Biochemistry and Biophysics. 239: 137-46. PMID 4004253 DOI: 10.1016/0003-9861(85)90820-3 |
0.34 |
|
| 1985 |
Hines RN, Levy JB, Conrad RD, Iversen PL, Shen ML, Renli AM, Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c Archives of Biochemistry and Biophysics. 237: 465-476. PMID 3838427 DOI: 10.1016/0003-9861(85)90300-5 |
0.325 |
|
| 1984 |
Raha C, Hines R, Bresnick E. Demonstration of microsomal oxygenation of the benzo ring of 6-nitrobenzo[a]pyrene by thin-layer chromatography. Journal of Chromatography. 291: 231-9. PMID 6539786 DOI: 10.1016/S0021-9673(00)95024-6 |
0.306 |
|
| 1984 |
Omiecinski CJ, Hines RN, Foldes RL, Levy JB, Bresnick E. Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: expression of a 4-kilobase messenger RNA. Archives of Biochemistry and Biophysics. 227: 478-93. PMID 6141764 DOI: 10.1016/0003-9861(83)90478-2 |
0.317 |
|
| 1982 |
Bresnick E, Levy J, Hines RN, Levin W, Thomas PE. The molecular cloning of cytochrome P-450c information. Archives of Biochemistry and Biophysics. 212: 501-7. PMID 7034652 DOI: 10.1016/0003-9861(81)90393-3 |
0.323 |
|
| 1982 |
Wiebkin P, Sieg MS, Nelson RE, Hines RN, Prough RA. Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line p815) cells Biochemical Pharmacology. 31: 2921-2928. PMID 6814447 DOI: 10.1016/0006-2952(82)90264-7 |
0.331 |
|
| Show low-probability matches. |