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Christopher Williamson Davies, Ph.D. - Publications

Affiliations: 
2008-2013 Chemistry Purdue University, West Lafayette, IN, United States 
 2013-2015 Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
 2015- Antibody Engineering Genentech, Inc., San Francisco, CA, United States 
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Noreng S, Ota N, Sun Y, Ho H, Johnson M, Arthur CP, Schneider K, Lehoux I, Davies CW, Mortara K, Wong K, Seshasayee D, Masureel M, Payandeh J, Yi T, et al. Structure of the core human NADPH oxidase NOX2. Nature Communications. 13: 6079. PMID 36241643 DOI: 10.1038/s41467-022-33711-0  0.307
2022 Yuan L, Gao F, Lv Z, Nayak D, Nayak A, Santos Bury PD, Cano KE, Jia L, Oleinik N, Atilgan FC, Ogretmen B, Williams KM, Davies C, El Oualid F, Wasmuth EV, et al. Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6. Nature Communications. 13: 4880. PMID 35986001 DOI: 10.1038/s41467-022-32613-5  0.459
2021 Singh A, Izac JR, Schuler EJA, Patel DT, Davies C, Marconi RT. High resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain. Pathogens and Disease. PMID 34117751 DOI: 10.1093/femspd/ftab030  0.364
2019 Johnsen U, Reinhardt A, Landan G, Tria FDK, Turner JM, Davies C, Schönheit P. New views on an old enzyme: allosteric regulation and evolution of archaeal pyruvate kinases. The Febs Journal. PMID 30945446 DOI: 10.1111/Febs.14837  0.368
2018 Lv Z, Yuan L, Atkison JH, Williams KM, Vega R, Sessions EH, Divlianska DB, Davies C, Chen Y, Olsen SK. Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nature Communications. 9: 5145. PMID 30514846 DOI: 10.2210/Pdb6Cwy/Pdb  0.403
2018 Lin MG, Schöneberg J, Davies CW, Ren X, Hurley JH. The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion. Molecular Biology of the Cell. PMID 29540529 DOI: 10.1091/Mbc.E17-04-0258  0.664
2015 Davies CW, Stjepanovic G, Hurley JH. How the Atg1 complex assembles to initiate autophagy. Autophagy. 11: 185-6. PMID 25700739 DOI: 10.4161/15548627.2014.984281  0.603
2014 Fedarovich A, Cook E, Tomberg J, Nicholas RA, Davies C. Structural effect of the Asp345a insertion in penicillin-binding protein 2 from penicillin-resistant strains of Neisseria gonorrhoeae. Biochemistry. 53: 7596-603. PMID 25403720 DOI: 10.1021/Bi5011317  0.326
2014 Stjepanovic G, Davies CW, Stanley RE, Ragusa MJ, Kim do J, Hurley JH. Assembly and dynamics of the autophagy-initiating Atg1 complex. Proceedings of the National Academy of Sciences of the United States of America. 111: 12793-8. PMID 25139988 DOI: 10.1073/Pnas.1407214111  0.709
2014 Nuñez JK, Kranzusch PJ, Noeske J, Wright AV, Davies CW, Doudna JA. Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nature Structural & Molecular Biology. 21: 528-34. PMID 24793649 DOI: 10.1038/Nsmb.2820  0.354
2014 Shrestha RK, Ronau JA, Davies CW, Guenette RG, Strieter ER, Paul LN, Das C. Insights into the mechanism of deubiquitination by JAMM deubiquitinases from cocrystal structures of the enzyme with the substrate and product. Biochemistry. 53: 3199-217. PMID 24787148 DOI: 10.1021/Bi5003162  0.637
2013 Davies CW, Paul LN, Das C. Mechanism of recruitment and activation of the endosome-associated deubiquitinase AMSH. Biochemistry. 52: 7818-29. PMID 24151880 DOI: 10.1021/Bi401106B  0.669
2013 Solomons JT, Johnsen U, Schönheit P, Davies C. 3-Phosphoglycerate is an allosteric activator of pyruvate kinase from the hyperthermophilic archaeon Pyrobaculum aerophilum. Biochemistry. 52: 5865-75. PMID 23879743 DOI: 10.1021/bi400761b  0.391
2013 Arnst JL, Davies CW, Raja SM, Das C, Natarajan A. High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity. Analytical Biochemistry. 440: 71-7. PMID 23747283 DOI: 10.1016/J.Ab.2013.05.017  0.573
2013 Davies CW, Das C. HHARI is one HECT of a RING. Structure (London, England : 1993). 21: 872-4. PMID 23747110 DOI: 10.1016/J.Str.2013.05.003  0.613
2012 Peat TS, Böttcher C, Newman J, Lucent D, Cowieson N, Davies C. Crystal structure of an indole-3-acetic acid amido synthetase from grapevine involved in auxin homeostasis Plant Cell. 24: 4525-4538. PMID 23136372 DOI: 10.1105/tpc.112.102921  0.372
2012 Davies CW, Chaney J, Korbel G, Ringe D, Petsko GA, Ploegh H, Das C. The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorganic & Medicinal Chemistry Letters. 22: 3900-4. PMID 22617491 DOI: 10.1016/J.Bmcl.2012.04.124  0.741
2012 Fedarovich A, Nicholas RA, Davies C. The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis. Journal of Molecular Biology. 418: 316-30. PMID 22365933 DOI: 10.1016/J.Jmb.2012.02.021  0.326
2011 Davies CW, Paul LN, Kim MI, Das C. Structural and thermodynamic comparison of the catalytic domain of AMSH and AMSH-LP: nearly identical fold but different stability. Journal of Molecular Biology. 413: 416-29. PMID 21888914 DOI: 10.1016/J.Jmb.2011.08.029  0.677
2010 Nicola G, Tomberg J, Pratt RF, Nicholas RA, Davies C. Crystal structures of covalent complexes of β-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity. Biochemistry. 49: 8094-104. PMID 20726582 DOI: 10.1021/Bi100879M  0.347
2010 Boudreaux DA, Maiti TK, Davies CW, Das C. Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proceedings of the National Academy of Sciences of the United States of America. 107: 9117-22. PMID 20439756 DOI: 10.1073/Pnas.0910870107  0.681
2010 Fedarovich A, Nicholas RA, Davies C. Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis. Journal of Molecular Biology. 398: 54-65. PMID 20206184 DOI: 10.1016/J.Jmb.2010.02.046  0.437
2008 Sauvage E, Powell AJ, Heilemann J, Josephine HR, Charlier P, Davies C, Pratt RF. Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle. Journal of Molecular Biology. 381: 383-93. PMID 18602645 DOI: 10.1016/J.Jmb.2008.06.012  0.404
2007 Tsybovsky Y, Donato H, Krupenko NI, Davies C, Krupenko SA. Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases. Biochemistry. 46: 2917-29. PMID 17302434 DOI: 10.1021/bi0619573  0.442
2006 Fedarovich A, Tomberg J, Nicholas RA, Davies C. Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae. Acta Crystallographica. Section D, Biological Crystallography. 62: 971-9. PMID 16929097 DOI: 10.1107/S0907444906020737  0.341
2006 Powell AJ, Liu ZJ, Nicholas RA, Davies C. Crystal structures of the lytic transglycosylase MltA from N.gonorrhoeae and E.coli: insights into interdomain movements and substrate binding. Journal of Molecular Biology. 359: 122-36. PMID 16618494 DOI: 10.1016/J.Jmb.2006.03.023  0.461
2005 Nicola G, Fedarovich A, Nicholas RA, Davies C. A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli. The Biochemical Journal. 392: 55-63. PMID 16038617 DOI: 10.1042/Bj20050449  0.435
2005 Nicola G, Peddi S, Stefanova M, Nicholas RA, Gutheil WG, Davies C. Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation. Biochemistry. 44: 8207-17. PMID 15938610 DOI: 10.1021/Bi0473004  0.371
2004 Swan MK, Hansen T, Schönheit P, Davies C. Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes. Biochemistry. 43: 14088-95. PMID 15518558 DOI: 10.1021/bi048608y  0.308
2004 Solomons JT, Zimmerly EM, Burns S, Krishnamurthy N, Swan MK, Krings S, Muirhead H, Chirgwin J, Davies C. The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. Journal of Molecular Biology. 342: 847-60. PMID 15342241 DOI: 10.1016/J.Jmb.2004.07.085  0.324
2004 Swan MK, Hansen T, Schönheit P, Davies C. A novel phosphoglucose isomerase (PGI)/phosphomannose isomerase from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16-A resolution. The Journal of Biological Chemistry. 279: 39838-45. PMID 15252053 DOI: 10.1074/jbc.M406855200  0.434
2004 Chumanevich AA, Krupenko SA, Davies C. The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain. The Journal of Biological Chemistry. 279: 14355-64. PMID 14729668 DOI: 10.1074/jbc.M313934200  0.452
2004 Stefanova ME, Tomberg J, Davies C, Nicholas RA, Gutheil WG. Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4. European Journal of Biochemistry / Febs. 271: 23-32. PMID 14686916 DOI: 10.1046/J.1432-1033.2003.03886.X  0.33
2003 Nicholas RA, Krings S, Tomberg J, Nicola G, Davies C. Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex. The Journal of Biological Chemistry. 278: 52826-33. PMID 14555648 DOI: 10.1074/jbc.M310177200  0.41
2003 Swan MK, Solomons JT, Beeson CC, Hansen T, Schönheit P, Davies C. Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus. The Journal of Biological Chemistry. 278: 47261-8. PMID 12970347 DOI: 10.1074/Jbc.M308603200  0.349
2003 Davies C, Muirhead H, Chirgwin J. The structure of human phosphoglucose isomerase complexed with a transition-state analogue. Acta Crystallographica. Section D, Biological Crystallography. 59: 1111-3. PMID 12777791 DOI: 10.1107/S0907444903007352  0.315
2003 Davies C, Muirhead H. Structure of native phosphoglucose isomerase from rabbit: conformational changes associated with catalytic function. Acta Crystallographica. Section D, Biological Crystallography. 59: 453-65. PMID 12595702 DOI: 10.1107/S0907444902023387  0.44
2002 Chumanevich AA, Davies C, Krupenko SA. Crystallization and preliminary X-ray diffraction analysis of recombinant hydrolase domain of 10-formyltetrahydrofolate dehydrogenase. Acta Crystallographica. Section D, Biological Crystallography. 58: 1841-2. PMID 12351832  0.341
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