Year |
Citation |
Score |
2022 |
Nakamura H, Sekine H, Kato H, Masai H, Gradin K, Poellinger L. Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a non-canonical mechanism. The Journal of Biological Chemistry. 102137. PMID 35714766 DOI: 10.1016/j.jbc.2022.102137 |
0.434 |
|
2021 |
Kitajima S, Sun W, Lee KL, Ho JC, Oyadomari S, Okamoto T, Masai H, Poellinger L, Kato H. A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition. Scientific Reports. 11: 4538. PMID 33633164 DOI: 10.1038/s41598-021-83857-y |
0.308 |
|
2018 |
Kitajima S, Lee KL, Fujioka M, Sun W, You J, Chia GS, Wanibuchi H, Tomita S, Araki M, Kato H, Poellinger L. Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells. Oncotarget. 9: 19123-19135. PMID 29721188 DOI: 10.18632/oncotarget.24919 |
0.337 |
|
2018 |
Suzuki N, Vojnovic N, Lee KL, Yang H, Gradin K, Poellinger L. HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters. Experimental Cell Research. 366: 181-191. PMID 29574021 DOI: 10.1016/j.yexcr.2018.03.020 |
0.426 |
|
2018 |
Nakamura H, Bono H, Hiyama K, Kawamoto T, Kato Y, Nakanishi T, Nishiyama M, Hiyama E, Hirohashi N, Sueoka E, Poellinger L, Tanimoto K. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions. Plos One. 13: e0192136. PMID 29466367 DOI: 10.1371/journal.pone.0192136 |
0.315 |
|
2017 |
Ho JC, Abdullah LN, Pang QY, Jha S, Chow EK, Yang H, Kato H, Poellinger L, Ueda J, Lee KL. Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway. Plos One. 12: e0188051. PMID 29145444 DOI: 10.1371/Journal.Pone.0188051 |
0.306 |
|
2017 |
Han J, Li J, Ho JC, Chia GS, Kato H, Jha S, Yang H, Poellinger L, Lee KL. Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells. Scientific Reports. 7: 4108. PMID 28642487 DOI: 10.1038/s41598-017-04333-0 |
0.394 |
|
2017 |
Zheng X, Narayanan S, Zheng X, Luecke-Johansson S, Gradin K, Catrina SB, Poellinger L, Pereira TS. A Notch-independent Mechanism Contributes to the Induction of Hes1 Gene Expression in Response to Hypoxia in P19 cells. Experimental Cell Research. PMID 28602625 DOI: 10.1016/j.yexcr.2017.06.006 |
0.708 |
|
2017 |
Luecke-Johansson S, Gralla M, Rundqvist H, Ho JC, Johnson RS, Gradin K, Poellinger L. A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase. Molecular and Cellular Biology. PMID 28416634 DOI: 10.1128/Mcb.00630-16 |
0.3 |
|
2017 |
Suzuki N, Gradin K, Poellinger L, Yamamoto M. Regulation of hypoxia-inducible gene expression after HIF activation. Experimental Cell Research. PMID 28286304 DOI: 10.1016/J.Yexcr.2017.03.013 |
0.487 |
|
2015 |
Jakubauskiene E, Vilys L, Makino Y, Poellinger L, Kanopka A. Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia. The Journal of Biological Chemistry. 290: 18079-89. PMID 26023237 DOI: 10.1074/jbc.M115.639690 |
0.358 |
|
2015 |
Kobayashi S, Yamashita T, Ohneda K, Nagano M, Kimura K, Nakai H, Poellinger L, Ohneda O. Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 20: 224-41. PMID 25626335 DOI: 10.1111/gtc.12215 |
0.366 |
|
2014 |
Niemi H, Honkonen K, Korpisalo P, Huusko J, Kansanen E, Merentie M, Rissanen TT, André H, Pereira T, Poellinger L, Alitalo K, Ylä-Herttuala S. HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery. European Journal of Clinical Investigation. 44: 989-99. PMID 25208310 DOI: 10.1111/Eci.12333 |
0.629 |
|
2014 |
Ng KP, Manjeri A, Lee KL, Huang W, Tan SY, Chuah CT, Poellinger L, Ong ST. Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition. Blood. 123: 3316-26. PMID 24705490 DOI: 10.1182/blood-2013-07-511907 |
0.376 |
|
2014 |
Aesoy R, Gradin K, Aasrud KS, Hoivik EA, Ruas JL, Poellinger L, Bakke M. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Molecular Cancer. 13: 54. PMID 24618291 DOI: 10.1186/1476-4598-13-54 |
0.761 |
|
2014 |
Zheng X, Zhou AX, Rouhi P, Uramoto H, Borén J, Cao Y, Pereira T, Akyürek LM, Poellinger L. Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proceedings of the National Academy of Sciences of the United States of America. 111: 2560-5. PMID 24550283 DOI: 10.1073/pnas.1320815111 |
0.659 |
|
2013 |
Khalesi E, Nakamura H, Leong Lee K, Chandra Putra A, Fukazawa T, Kawahara Y, Makino Y, Poellinger L, Yuge L, Tanimoto K. The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms. Biochemical and Biophysical Research Communications. PMID 24513211 DOI: 10.1016/j.bbrc.2013.10.083 |
0.368 |
|
2013 |
Khalesi E, Nakamura H, Lee KL, Putra AC, Fukazawa T, Kawahara Y, Makino Y, Poellinger L, Yuge L, Tanimoto K. The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms. Biochemical and Biophysical Research Communications. 441: 499-506. PMID 24383088 |
0.453 |
|
2012 |
Hao N, Lee KL, Furness SG, Bosdotter C, Poellinger L, Whitelaw ML. Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling. Molecular Pharmacology. 82: 1082-93. PMID 22936816 DOI: 10.1124/mol.112.078873 |
0.375 |
|
2012 |
Zheng X, Zheng X, Wang X, Ma Z, Gupta Sunkari V, Botusan I, Takeda T, Björklund A, Inoue M, Catrina SB, Brismar K, Poellinger L, Pereira TS. Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death & Disease. 3: e322. PMID 22695615 DOI: 10.1038/cddis.2012.66 |
0.641 |
|
2012 |
Stiehl DP, Bordoli MR, Abreu-Rodríguez I, Wollenick K, Schraml P, Gradin K, Poellinger L, Kristiansen G, Wenger RH. Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene. 31: 2283-97. PMID 21927022 DOI: 10.1038/onc.2011.417 |
0.332 |
|
2012 |
Poellinger L. Mechanisms of gene regulation in hypoxia: Role of hypoxia-inducible factors in regulation of the epigenetic landscape of target cells Vascular Pharmacology. 56: 314-315. DOI: 10.1016/J.VPH.2011.08.026 |
0.421 |
|
2011 |
Florczyk U, Czauderna S, Stachurska A, Tertil M, Nowak W, Kozakowska M, Poellinger L, Jozkowicz A, Loboda A, Dulak J. Opposite effects of HIF-1α and HIF-2α on the regulation of IL-8 expression in endothelial cells. Free Radical Biology & Medicine. 51: 1882-92. PMID 21925595 DOI: 10.1016/j.freeradbiomed.2011.08.023 |
0.31 |
|
2010 |
Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F, Johnson RS. The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metabolism. 11: 364-78. PMID 20399150 DOI: 10.1016/J.Cmet.2010.03.001 |
0.383 |
|
2010 |
Main H, Lee KL, Yang H, Haapa-Paananen S, Edgren H, Jin S, Sahlgren C, Kallioniemi O, Poellinger L, Lim B, Lendahl U. Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells. Experimental Cell Research. 316: 1610-24. PMID 20034489 DOI: 10.1016/J.Yexcr.2009.12.012 |
0.383 |
|
2010 |
Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. The Journal of Biological Chemistry. 285: 2601-9. PMID 19880525 DOI: 10.1074/jbc.M109.021824 |
0.832 |
|
2009 |
Lendahl U, Lee KL, Yang H, Poellinger L. Generating specificity and diversity in the transcriptional response to hypoxia. Nature Reviews. Genetics. 10: 821-32. PMID 19884889 DOI: 10.1038/nrg2665 |
0.388 |
|
2009 |
Loboda A, Stachurska A, Florczyk U, Rudnicka D, Jazwa A, Wegrzyn J, Kozakowska M, Stalinska K, Poellinger L, Levonen AL, Yla-Herttuala S, Jozkowicz A, Dulak J. HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells. Antioxidants & Redox Signaling. 11: 1501-17. PMID 19254160 DOI: 10.1089/ars.2008.2211 |
0.329 |
|
2009 |
Takacova M, Holotnakova T, Vondracek J, Machala M, Pencikova K, Gradin K, Poellinger L, Pastorek J, Pastorekova S, Kopacek J. Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX. The Biochemical Journal. 419: 419-25. PMID 19154183 DOI: 10.1042/BJ20080952 |
0.438 |
|
2008 |
Botusan IR, Sunkari VG, Savu O, Catrina AI, Grünler J, Lindberg S, Pereira T, Ylä-Herttuala S, Poellinger L, Brismar K, Catrina SB. Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 19426-31. PMID 19057015 DOI: 10.1073/pnas.0805230105 |
0.752 |
|
2008 |
Ohradanova A, Gradin K, Barathova M, Zatovicova M, Holotnakova T, Kopacek J, Parkkila S, Poellinger L, Pastorekova S, Pastorek J. Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2. British Journal of Cancer. 99: 1348-56. PMID 18813310 DOI: 10.1038/sj.bjc.6604685 |
0.441 |
|
2008 |
Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proceedings of the National Academy of Sciences of the United States of America. 105: 6392-7. PMID 18427106 DOI: 10.1073/pnas.0802047105 |
0.486 |
|
2008 |
Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 133: 223-34. PMID 18423195 DOI: 10.1016/J.Cell.2008.02.038 |
0.402 |
|
2008 |
Nakamura H, Tanimoto K, Hiyama K, Yunokawa M, Kawamoto T, Kato Y, Yoshiga K, Poellinger L, Hiyama E, Nishiyama M. Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2. Oncogene. 27: 4200-9. PMID 18345027 DOI: 10.1038/onc.2008.58 |
0.417 |
|
2008 |
Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, ... ... Poellinger L, et al. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 3368-73. PMID 18299578 DOI: 10.1073/pnas.0711591105 |
0.834 |
|
2008 |
Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi T, Goto K, Ohneda K, Fujii-Kuriyama Y, Poellinger L, Yamamoto M. Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS. Molecular and Cellular Biology. 28: 1285-97. PMID 18070924 DOI: 10.1128/Mcb.01332-07 |
0.355 |
|
2007 |
Ruas JL, Lendahl U, Poellinger L. Modulation of vascular gene expression by hypoxia. Current Opinion in Lipidology. 18: 508-14. PMID 17885420 DOI: 10.1097/MOL.0b013e3282efe49d |
0.815 |
|
2007 |
Mason SD, Rundqvist H, Papandreou I, Duh R, McNulty WJ, Howlett RA, Olfert IM, Sundberg CJ, Denko NC, Poellinger L, Johnson RS. HIF-1alpha in endurance training: suppression of oxidative metabolism. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R2059-69. PMID 17855495 DOI: 10.1152/Ajpregu.00335.2007 |
0.486 |
|
2007 |
Löfstedt T, Fredlund E, Holmquist-Mengelbier L, Pietras A, Ovenberger M, Poellinger L, Påhlman S. Hypoxia inducible factor-2alpha in cancer. Cell Cycle (Georgetown, Tex.). 6: 919-26. PMID 17404509 DOI: 10.4161/cc.6.8.4133 |
0.512 |
|
2007 |
Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C. Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells. The Journal of Biological Chemistry. 282: 14073-82. PMID 17355974 DOI: 10.1074/jbc.M700732200 |
0.61 |
|
2007 |
Ronkainen VP, Ronkainen JJ, Hänninen SL, Leskinen H, Ruas JL, Pereira T, Poellinger L, Vuolteenaho O, Tavi P. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1821-30. PMID 17341685 DOI: 10.1096/Fj.06-7294Com |
0.78 |
|
2006 |
Pereira T, Zheng X, Poellinger L. Degradation of the hypoxia-inducible factor 1alpha: where does it happen? Cell Cycle (Georgetown, Tex.). 5: 2720-2. PMID 17172857 DOI: 10.4161/cc.5.23.3536 |
0.797 |
|
2006 |
Welford SM, Bedogni B, Gradin K, Poellinger L, Broome Powell M, Giaccia AJ. HIF1alpha delays premature senescence through the activation of MIF. Genes & Development. 20: 3366-71. PMID 17142669 DOI: 10.1101/Gad.1471106 |
0.398 |
|
2006 |
Holmquist-Mengelbier L, Fredlund E, Löfstedt T, Noguera R, Navarro S, Nilsson H, Pietras A, Vallon-Christersson J, Borg A, Gradin K, Poellinger L, Påhlman S. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell. 10: 413-23. PMID 17097563 DOI: 10.1016/j.ccr.2006.08.026 |
0.594 |
|
2006 |
Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, Axelson M, Biberfeld P, Poellinger L, Brismar K. Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4506-14. PMID 16899596 DOI: 10.1158/1078-0432.CCR-05-2473 |
0.505 |
|
2006 |
Zheng X, Ruas JL, Cao R, Salomons FA, Cao Y, Poellinger L, Pereira T. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Molecular and Cellular Biology. 26: 4628-41. PMID 16738327 DOI: 10.1128/MCB.02236-05 |
0.833 |
|
2006 |
Kashuba EV, Gradin K, Isaguliants M, Szekely L, Poellinger L, Klein G, Kazlauskas A. Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein. The Journal of Biological Chemistry. 281: 1215-23. PMID 16257957 DOI: 10.1074/Jbc.M509036200 |
0.317 |
|
2005 |
Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U, Bondesson M. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Developmental Cell. 9: 617-28. PMID 16256737 DOI: 10.1016/j.devcel.2005.09.010 |
0.815 |
|
2005 |
Pajusola K, Künnapuu J, Vuorikoski S, Soronen J, André H, Pereira T, Korpisalo P, Ylä-Herttuala S, Poellinger L, Alitalo K. Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1365-7. PMID 15958522 DOI: 10.1096/Fj.05-3720Fje |
0.72 |
|
2005 |
Nakamura H, Makino Y, Okamoto K, Poellinger L, Ohnuma K, Morimoto C, Tanaka H. TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 7592-9. PMID 15944259 |
0.509 |
|
2005 |
Ruas JL, Poellinger L. Hypoxia-dependent activation of HIF into a transcriptional regulator. Seminars in Cell & Developmental Biology. 16: 514-22. PMID 15908239 DOI: 10.1016/j.semcdb.2005.04.001 |
0.792 |
|
2005 |
Ameln H, Gustafsson T, Sundberg CJ, Okamoto K, Jansson E, Poellinger L, Makino Y. Physiological activation of hypoxia inducible factor-1 in human skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1009-11. PMID 15811877 DOI: 10.1096/fj.04-2304fje |
0.433 |
|
2005 |
Nilsson H, Jögi A, Beckman S, Harris AL, Poellinger L, Påhlman S. HIF-2alpha expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia. Experimental Cell Research. 303: 447-56. PMID 15652356 DOI: 10.1016/j.yexcr.2004.10.003 |
0.581 |
|
2005 |
Ruas JL, Poellinger L, Pereira T. Role of CBP in regulating HIF-1-mediated activation of transcription. Journal of Cell Science. 118: 301-11. PMID 15615775 DOI: 10.1242/jcs.01617 |
0.837 |
|
2004 |
Catrina SB, Okamoto K, Pereira T, Brismar K, Poellinger L. Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function. Diabetes. 53: 3226-32. PMID 15561954 DOI: 10.2337/diabetes.53.12.3226 |
0.794 |
|
2004 |
Löfstedt T, Jögi A, Sigvardsson M, Gradin K, Poellinger L, Påhlman S, Axelson H. Induction of ID2 expression by hypoxia-inducible factor-1: a role in dedifferentiation of hypoxic neuroblastoma cells. The Journal of Biological Chemistry. 279: 39223-31. PMID 15252039 DOI: 10.1074/jbc.M402904200 |
0.435 |
|
2004 |
Poellinger L, Johnson RS. HIF-1 and hypoxic response: The plot thickens Current Opinion in Genetics and Development. 14: 81-85. PMID 15108809 DOI: 10.1016/J.Gde.2003.12.006 |
0.441 |
|
2003 |
Tanimoto K, Yoshiga K, Eguchi H, Kaneyasu M, Ukon K, Kumazaki T, Oue N, Yasui W, Imai K, Nakachi K, Poellinger L, Nishiyama M. Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance. Carcinogenesis. 24: 1779-83. PMID 12919954 DOI: 10.1093/carcin/bgg132 |
0.576 |
|
2003 |
Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product. The Journal of Biological Chemistry. 278: 6816-23. PMID 12468553 DOI: 10.1074/jbc.M209297200 |
0.824 |
|
2002 |
Ruas JL, Poellinger L, Pereira T. Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein. The Journal of Biological Chemistry. 277: 38723-30. PMID 12133832 DOI: 10.1074/jbc.M205051200 |
0.824 |
|
2002 |
Makino Y, Kanopka A, Wilson WJ, Tanaka H, Poellinger L. Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus. The Journal of Biological Chemistry. 277: 32405-8. PMID 12119283 DOI: 10.1074/jbc.C200328200 |
0.572 |
|
2002 |
Wilson WJ, Poellinger L. The dietary flavonoid quercetin modulates HIF-1 alpha activity in endothelial cells. Biochemical and Biophysical Research Communications. 293: 446-50. PMID 12054621 DOI: 10.1016/S0006-291X(02)00244-9 |
0.633 |
|
2002 |
Fink T, Kazlauskas A, Poellinger L, Ebbesen P, Zachar V. Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1. Blood. 99: 2077-83. PMID 11877282 DOI: 10.1182/blood.V99.6.2077 |
0.492 |
|
2002 |
Makino Y, Cao R, Svensson K, Bertilsson G, Asman M, Tanaka H, Cao Y, Berkenstam A, Poellinger L. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature. 414: 550-4. PMID 11734856 DOI: 10.1038/35107085 |
0.416 |
|
2000 |
Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. The Embo Journal. 19: 4298-309. PMID 10944113 DOI: 10.1093/emboj/19.16.4298 |
0.792 |
|
2000 |
Lando D, Pongratz I, Poellinger L, Whitelaw ML. A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor. The Journal of Biological Chemistry. 275: 4618-27. PMID 10671489 DOI: 10.1074/JBC.275.7.4618 |
0.567 |
|
2000 |
Carrero P, Okamoto K, Coumailleau P, O'Brien S, Tanaka H, Poellinger L. Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha. Molecular and Cellular Biology. 20: 402-15. PMID 10594042 DOI: 10.1128/MCB.20.1.402-415.2000 |
0.658 |
|
1999 |
Gradin K, Toftgârd R, Poellinger L, Berghard A. Repression of dioxin signal transduction in fibroblasts. Identification Of a putative repressor associated with Arnt. The Journal of Biological Chemistry. 274: 13511-8. PMID 10224119 DOI: 10.1074/jbc.274.19.13511 |
0.434 |
|
1999 |
Ema M, Hirota K, Mimura J, Abe H, Yodoi J, Sogawa K, Poellinger L, Fujii-Kuriyama Y. Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. The Embo Journal. 18: 1905-14. PMID 10202154 DOI: 10.1093/emboj/18.7.1905 |
0.45 |
|
1999 |
Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 274: 6519-25. PMID 10037745 DOI: 10.1074/jbc.274.10.6519 |
0.605 |
|
1999 |
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L. Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha. The Embo Journal. 17: 6573-86. PMID 9822602 DOI: 10.1093/emboj/17.22.6573 |
0.648 |
|
1997 |
Kallio PJ, Pongratz I, Gradin K, McGuire J, Poellinger L. Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 94: 5667-72. PMID 9159130 DOI: 10.1073/PNAS.94.11.5667 |
0.64 |
|
1996 |
Gradin K, McGuire J, Wenger RH, Kvietikova I, fhitelaw ML, Toftgård R, Tora L, Gassmann M, Poellinger L. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Molecular and Cellular Biology. 16: 5221-31. PMID 8816435 DOI: 10.1128/Mcb.16.10.5221 |
0.618 |
|
1995 |
Antonsson C, Arulampalam V, Whitelaw ML, Pettersson S, Poellinger L. Constitutive function of the basic helix-loop-helix/PAS factor Arnt. Regulation of target promoters via the E box motif. The Journal of Biological Chemistry. 270: 13968-72. PMID 7775458 DOI: 10.1074/JBC.270.23.13968 |
0.313 |
|
1993 |
Pimental RA, Liang B, Yee GK, Wilhelmsson A, Poellinger L, Paulson KE. Dioxin receptor and C/EBP regulate the function of the glutathione S-transferase Ya gene xenobiotic response element. Molecular and Cellular Biology. 13: 4365-4373. DOI: 10.1128/MCB.13.7.4365 |
0.411 |
|
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