| Year |
Citation |
Score |
| 2020 |
Zidon TM, Padilla J, Fritsche KL, Welly RJ, McCabe LT, Stricklin OE, Frank AP, Park YM, Clegg DJ, Lubahn D, Kanaley J, Vieira-Potter V. Effects of ERβ and ERα on OVX-induced changes in adiposity and insulin resistance. The Journal of Endocrinology. PMID 32053493 DOI: 10.1530/Joe-19-0321 |
0.331 |
|
| 2019 |
Iyer MS, Paszkiewicz RL, Bergman RN, Richey JM, Woolcott OO, Asare Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Clegg DJ, Kabir M. Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs. American Journal of Physiology. Endocrinology and Metabolism. PMID 31237449 DOI: 10.1152/Ajpendo.00539.2018 |
0.388 |
|
| 2019 |
Fatima LA, Campello RS, Barreto-Andrade JN, Passarelli M, Clegg DJ, Machado UF. Estradiol stimulates adipogenesis and Slc2a4/GLUT4 expression via ESR1-mediated activation of CEBPA. Molecular and Cellular Endocrinology. 110447. PMID 31100494 DOI: 10.1016/J.Mce.2019.05.006 |
0.323 |
|
| 2019 |
Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metabolism. 29: 1232. PMID 31067449 DOI: 10.1016/J.Cmet.2019.04.006 |
0.31 |
|
| 2019 |
PASZKIEWICZ RK, BERGMAN RN, FRANK A, WOOLCOTT OO, SOUZA SANTOS RD, IYER MS, CLEGG D, KABIR M. 1761-P: Brain-Restricted CB1-Receptor Antagonists Increase Oxygen Consumption Rate and Promote Beiging in 3T3-L1 Adipocytes Similar to Rimonabant Suggesting that Central Effects Can Be Avoided Diabetes. 68: 1761-P. DOI: 10.2337/Db19-1761-P |
0.32 |
|
| 2018 |
Frank AP, de Souza Santos R, Palmer BF, Clegg DJ. Determinants of body fat distribution in humans may provide insight about obesity-related health risks. Journal of Lipid Research. PMID 30097511 DOI: 10.1194/Jlr.R086975 |
0.381 |
|
| 2018 |
PASZKIEWICZ RL, BERGMAN RN, RICHEY JM, IYER MS, WOOLCOTT OO, KOLKA CM, CLEGG D, KABIR M. Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2 Diabetes. 67: 2010-P. DOI: 10.2337/Db18-2010-P |
0.321 |
|
| 2017 |
de Souza Santos R, Camargo RL, Vanzela EC, Batista TM, Morato PN, Leite NC, Rovani JC, García-Arévalo M, Clegg DJ, Carneiro EM. Diet-induced glucose homeostasis dysregulation is enhanced by taurine supplementation in ovariectomized mice. Amino Acids. PMID 29282544 DOI: 10.1007/S00726-017-2533-Z |
0.385 |
|
| 2017 |
Fatima LA, Campello RS, Santos RS, Freitas HS, Frank AP, Machado UF, Clegg DJ. Estrogen receptor 1 (ESR1) regulates VEGFA in adipose tissue. Scientific Reports. 7: 16716. PMID 29196658 DOI: 10.1038/S41598-017-16686-7 |
0.346 |
|
| 2017 |
Frank AP, Palmer BF, Clegg DJ. Do estrogens enhance activation of brown and beiging of adipose tissues? Physiology & Behavior. PMID 28988965 DOI: 10.1016/J.Physbeh.2017.09.026 |
0.348 |
|
| 2017 |
Palmer BF, Clegg DJ. Non-shivering thermogenesis as a mechanism to facilitate sustainable weight loss. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 18: 819-831. PMID 28547916 DOI: 10.1111/Obr.12563 |
0.328 |
|
| 2017 |
Clegg D, Hevener AL, Moreau KL, Morselli E, Criollo A, Van Pelt RE, Vieira-Potter VJ. Sex Hormones and Cardiometabolic Health: Role of Estrogen and Estrogen Receptors. Endocrinology. PMID 28323912 DOI: 10.1210/En.2016-1677 |
0.344 |
|
| 2017 |
Morselli E, Santos RS, Criollo A, Nelson MD, Palmer BF, Clegg DJ. The effects of oestrogens and their receptors on cardiometabolic health. Nature Reviews. Endocrinology. PMID 28304393 DOI: 10.1038/Nrendo.2017.12 |
0.314 |
|
| 2016 |
Palmer BF, Clegg DJ. Physiology and pathophysiology of potassium homeostasis. Advances in Physiology Education. 40: 480-490. PMID 27756725 DOI: 10.1152/Advan.00121.2016 |
0.304 |
|
| 2016 |
Wang A, Luo J, Moore W, Alkhalidy H, Wu L, Zhang J, Zhen W, Wang Y, Clegg DJ, Bin Xu, Cheng Z, McMillan RP, Hulver MW, Liu D. GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro. Scientific Reports. 6: 34302. PMID 27698362 DOI: 10.1038/Srep34302 |
0.471 |
|
| 2016 |
Santiago AM, Clegg DJ, Routh VH. Estrogens modulate ventrolateral ventromedial hypothalamic glucose-inhibited neurons. Molecular Metabolism. 5: 823-33. PMID 27688996 DOI: 10.1016/J.Molmet.2016.08.002 |
0.327 |
|
| 2016 |
Rodriguez-Navas C, Morselli E, Clegg DJ. Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice. Molecular Metabolism. 5: 680-9. PMID 27656405 DOI: 10.1016/J.Molmet.2016.06.014 |
0.329 |
|
| 2016 |
Iyer MS, Bergman RN, Korman JE, Woolcott OO, Kabir M, Victor RG, Clegg DJ, Kolka C. Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet. Diabetes. PMID 27495220 DOI: 10.2337/Db16-0698 |
0.349 |
|
| 2016 |
Farman HH, Windahl SH, Westberg L, Isaksson H, Egecioglu E, Schele E, Ryberg H, Jansson JO, Tuukkanen J, Koskela A, Xie SK, Hahner L, Zehr J, Clegg DJ, Lagerquist MK, et al. Female Mice lacking Estrogen Receptor α in Hypothalamic Pro-opiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass. Endocrinology. en20161181. PMID 27254004 DOI: 10.1210/En.2016-1181 |
0.302 |
|
| 2016 |
Santos RS, Batista TM, Camargo RL, Morato PN, Borck PC, Leite NC, Kurauti MA, Wanschel AC, Nadal Á, Clegg DJ, Carneiro EM. "Lacking of estradiol reduces insulin exocytosis from pancreatic β-cells and increases hepatic insulin degradation". Steroids. PMID 27192429 DOI: 10.1016/J.Steroids.2016.05.002 |
0.373 |
|
| 2016 |
Frank AP, Clegg DJ. JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Fat. Jama. 315: 1919. PMID 27139076 DOI: 10.1001/Jama.2016.0972 |
0.337 |
|
| 2016 |
Hinton AO, He Y, Xia Y, Xu P, Yang Y, Saito K, Wang C, Yan X, Shu G, Henderson A, Clegg DJ, Khan SA, Reynolds C, Wu Q, Tong Q, et al. Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension. PMID 27091896 DOI: 10.1161/Hypertensionaha.116.07175 |
0.32 |
|
| 2016 |
Saito K, He Y, Yang Y, Zhu L, Wang C, Xu P, Hinton AO, Yan X, Zhao J, Fukuda M, Tong Q, Clegg DJ, Xu Y. PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Scientific Reports. 6: 23459. PMID 26988598 DOI: 10.1038/Srep23459 |
0.394 |
|
| 2016 |
Kim JS, Rizwan MZ, Clegg DJ, Anderson GM. Leptin Signaling is not Required for Anorexigenic Estradiol Effects in Female Mice. Endocrinology. en20151594. PMID 26937712 DOI: 10.1210/En.2015-1594 |
0.407 |
|
| 2016 |
Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, ... Clegg DJ, et al. 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26809497 DOI: 10.1093/Gerona/Glv309 |
0.339 |
|
| 2016 |
Farman H, Windahl S, Clegg D, Xie SK, Westberg L, Isaksson H, Egecioglu E, Schele E, Johnsson JO, Tuukkanen J, Hahner L, Zehr J, Lagerquist M, Ohlsson C. Mice lacking estrogen receptor [alpha] in hypothalamic POMC neurons display enhanced estrogenic response on cortical bone mass Bone Abstracts. DOI: 10.1530/Boneabs.5.Ht2 |
0.309 |
|
| 2015 |
Frank AP, Zechner JF, Clegg DJ. Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice. Obesity Surgery. PMID 26667161 DOI: 10.1007/S11695-015-2009-8 |
0.362 |
|
| 2015 |
Zhu L, Xu P, Cao X, Yang Y, Hinton AO, Xia Y, Saito K, Yan X, Zou F, Ding H, Wang C, Yan C, Saha P, Khan SA, Zhao J, ... Clegg DJ, et al. The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. en20151660. PMID 26375425 DOI: 10.1210/En.2015-1660 |
0.415 |
|
| 2015 |
Xu P, Cao X, He Y, Zhu L, Yang Y, Saito K, Wang C, Yan X, Hinton AO, Zou F, Ding H, Xia Y, Yan C, Shu G, Wu SP, ... Clegg DJ, et al. Estrogen receptor-α in medial amygdala neurons regulates body weight. The Journal of Clinical Investigation. 125: 2861-76. PMID 26098212 DOI: 10.1172/Jci80941 |
0.426 |
|
| 2015 |
Morselli E, Frank AP, Palmer BF, Rodriguez-Navas C, Criollo A, Clegg DJ. A sexually dimorphic hypothalamic response to chronic high-fat diet consumption. International Journal of Obesity (2005). PMID 26073655 DOI: 10.1038/Ijo.2015.114 |
0.402 |
|
| 2015 |
Hevener AL, Clegg DJ, Mauvais-Jarvis F. Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome. Molecular and Cellular Endocrinology. PMID 26033249 DOI: 10.1016/J.Mce.2015.05.020 |
0.359 |
|
| 2015 |
Neinast MD, Frank AP, Zechner JF, Li Q, Vishvanath L, Palmer BF, Aguirre V, Gupta RK, Clegg DJ. Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning. Molecular Metabolism. 4: 427-36. PMID 25973390 DOI: 10.1016/J.Molmet.2015.02.006 |
0.411 |
|
| 2015 |
Palmer BF, Clegg DJ. The sexual dimorphism of obesity. Molecular and Cellular Endocrinology. 402: 113-9. PMID 25578600 DOI: 10.1016/J.Mce.2014.11.029 |
0.409 |
|
| 2014 |
Morselli E, Criollo A, Rodriguez-Navas C, Clegg DJ. Chronic High Fat Diet Consumption Impairs Metabolic Health of Male Mice. Inflammation and Cell Signaling. 1: e561. PMID 26046098 DOI: 10.14800/Ics.561 |
0.42 |
|
| 2014 |
Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, ... ... Clegg DJ, et al. Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα. Cell Reports. 9: 633-45. PMID 25373903 DOI: 10.1016/J.Celrep.2014.09.025 |
0.394 |
|
| 2014 |
Kim M, Neinast MD, Frank AP, Sun K, Park J, Zehr JA, Vishvanath L, Morselli E, Amelotte M, Palmer BF, Gupta RK, Scherer PE, Clegg DJ. ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Molecular Metabolism. 3: 642-51. PMID 25161887 DOI: 10.1016/J.Molmet.2014.05.007 |
0.317 |
|
| 2014 |
Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A, Yan C, Ding H, Zhu L, Yu L, Yang B, ... ... Clegg DJ, et al. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. The Journal of Clinical Investigation. 124: 4351-62. PMID 25157819 DOI: 10.1172/Jci74726 |
0.33 |
|
| 2014 |
Palmer BF, Clegg DJ. Oxygen sensing and metabolic homeostasis. Molecular and Cellular Endocrinology. 397: 51-8. PMID 25132648 DOI: 10.1016/J.Mce.2014.08.001 |
0.307 |
|
| 2014 |
Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer--mechanisms underlying tumour progression and recurrence. Nature Reviews. Endocrinology. 10: 455-65. PMID 24935119 DOI: 10.1038/Nrendo.2014.94 |
0.316 |
|
| 2014 |
Frank A, Brown LM, Clegg DJ. The role of hypothalamic estrogen receptors in metabolic regulation. Frontiers in Neuroendocrinology. 35: 550-7. PMID 24882636 DOI: 10.1016/J.Yfrne.2014.05.002 |
0.452 |
|
| 2014 |
Picard A, Rouch C, Kassis N, Moullé VS, Croizier S, Denis RG, Castel J, Coant N, Davis K, Clegg DJ, Benoit SC, Prévot V, Bouret S, Luquet S, Le Stunff H, et al. Hippocampal lipoprotein lipase regulates energy balance in rodents. Molecular Metabolism. 3: 167-76. PMID 24634821 DOI: 10.1016/J.Molmet.2013.11.002 |
0.374 |
|
| 2014 |
Davis KE, Carstens EJ, Irani BG, Gent LM, Hahner LM, Clegg DJ. Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Hormones and Behavior. 66: 196-207. PMID 24560890 DOI: 10.1016/J.Yhbeh.2014.02.004 |
0.431 |
|
| 2014 |
Palmer BF, Clegg DJ. Ascent to altitude as a weight loss method: the good and bad of hypoxia inducible factor activation. Obesity (Silver Spring, Md.). 22: 311-7. PMID 23625659 DOI: 10.1002/Oby.20499 |
0.374 |
|
| 2013 |
Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J, Zeve D, D Hahner L, W Cox D, M Gent L, Xu Y, V Wang Z, A Khan S, Clegg DJ. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Molecular Metabolism. 2: 227-42. PMID 24049737 DOI: 10.1016/J.Molmet.2013.05.006 |
0.381 |
|
| 2013 |
Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH. Estrogen, astrocytes and the neuroendocrine control of metabolism. Reviews in Endocrine & Metabolic Disorders. 14: 331-8. PMID 24009071 DOI: 10.1007/S11154-013-9263-7 |
0.395 |
|
| 2013 |
Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocrine Reviews. 34: 309-38. PMID 23460719 DOI: 10.1210/Er.2012-1055 |
0.426 |
|
| 2013 |
Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/Jneurosci.1610-12.2013 |
0.303 |
|
| 2013 |
Brown LM, Clegg DJ. Estrogen and leptin regulation of endocrinological features of anorexia nervosa. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 237. PMID 23147480 DOI: 10.1038/Npp.2012.176 |
0.395 |
|
| 2012 |
Clegg DJ. Minireview: the year in review of estrogen regulation of metabolism. Molecular Endocrinology (Baltimore, Md.). 26: 1957-60. PMID 23051593 DOI: 10.1210/Me.2012-1284 |
0.43 |
|
| 2012 |
Castañeda TR, Abplanalp W, Um SH, Pfluger PT, Schrott B, Brown K, Grant E, Carnevalli L, Benoit SC, Morgan DA, Gilham D, Hui DY, Rahmouni K, Thomas G, Kozma SC, ... Clegg DJ, et al. Metabolic control by S6 kinases depends on dietary lipids. Plos One. 7: e32631. PMID 22412899 DOI: 10.1371/Journal.Pone.0032631 |
0.394 |
|
| 2012 |
Xu Y, Nedungadiuli T, Gent L, Elias C, Elmquist JK, Clegg D. It's ALL in the Hypothalamus! Sex, Reproduction, and Obesity. Biology of Reproduction. 87: 34-34. DOI: 10.1093/Biolreprod/87.S1.34 |
0.313 |
|
| 2012 |
Wang HH, Liu KJ, Clegg DJ, Portincasa P, Wang DQ. 470 Deletion of the Gpr30 Gene, a Novel Estrogen Receptor, Results in Increased Susceptibility to Cholesterol Gallstone Formation in Mice Gastroenterology. 142: S-98-S-99. DOI: 10.1016/S0016-5085(12)60375-8 |
0.307 |
|
| 2011 |
Speakman JR, Levitsky DA, Allison DB, Bray MS, de Castro JM, Clegg DJ, Clapham JC, Dulloo AG, Gruer L, Haw S, Hebebrand J, Hetherington MM, Higgs S, Jebb SA, Loos RJ, et al. Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Disease Models & Mechanisms. 4: 733-45. PMID 22065844 DOI: 10.1242/Dmm.008698 |
0.367 |
|
| 2011 |
Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metabolism. 14: 453-65. PMID 21982706 DOI: 10.1016/J.Cmet.2011.08.009 |
0.392 |
|
| 2011 |
Kilpeläinen TO, Zillikens MC, StanÄákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, ... ... Clegg DJ, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics. 43: 753-60. PMID 21706003 DOI: 10.1038/Ng.866 |
0.366 |
|
| 2011 |
Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. The Journal of Clinical Investigation. 121: 1858-70. PMID 21490391 DOI: 10.1172/Jci43378 |
0.335 |
|
| 2011 |
Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiologica (Oxford, England). 203: 259-69. PMID 21281456 DOI: 10.1111/J.1748-1716.2010.02237.X |
0.386 |
|
| 2011 |
Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE. Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice. The Journal of Clinical Investigation. 121: 604-12. PMID 21245576 DOI: 10.1172/Jci41702 |
0.398 |
|
| 2011 |
Clegg DJ, Gotoh K, Kemp C, Wortman MD, Benoit SC, Brown LM, D'Alessio D, Tso P, Seeley RJ, Woods SC. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & Behavior. 103: 10-6. PMID 21241723 DOI: 10.1016/J.Physbeh.2011.01.010 |
0.424 |
|
| 2011 |
Irani BG, Xiang Z, Yarandi HN, Holder JR, Moore MC, Bauzo RM, Proneth B, Shaw AM, Millard WJ, Chambers JB, Benoit SC, Clegg DJ, Haskell-Luevano C. Implication of the melanocortin-3 receptor in the regulation of food intake. European Journal of Pharmacology. 660: 80-7. PMID 21199647 DOI: 10.1016/J.Ejphar.2010.10.101 |
0.371 |
|
| 2011 |
Davis JF, Choi DL, Clegg DJ, Benoit SC. Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiology & Behavior. 103: 39-43. PMID 21036184 DOI: 10.1016/J.Physbeh.2010.10.017 |
0.343 |
|
| 2011 |
Davis JF, Choi DL, Schurdak JD, Fitzgerald MF, Clegg DJ, Lipton JW, Figlewicz DP, Benoit SC. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological Psychiatry. 69: 668-74. PMID 21035790 DOI: 10.1016/J.Biopsych.2010.08.028 |
0.428 |
|
| 2011 |
Ford J, Hajibeigi A, Long M, Hahner L, Gore C, Hsieh JT, Clegg D, Zerwekh J, Öz OK. GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice Journal of Bone and Mineral Research. 26: 298-307. PMID 20734455 DOI: 10.1002/Jbmr.209 |
0.338 |
|
| 2010 |
Zheng Q, Zhu J, Shanabrough M, Borok E, Benoit SC, Horvath TL, Clegg DJ, Reizes O. Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice. Neuroscience. 171: 1032-40. PMID 20923696 DOI: 10.1016/J.Neuroscience.2010.09.060 |
0.417 |
|
| 2010 |
Irani BG, Donato J, Olson DP, Lowell BB, Sacktor TC, Reyland ME, Tolson KP, Zinn AR, Ueta Y, Sakata I, Zigman JM, Elias CF, Clegg DJ. Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 170: 1065-79. PMID 20691763 DOI: 10.1016/J.Neuroscience.2010.07.064 |
0.317 |
|
| 2010 |
Brown LM, Gent L, Davis K, Clegg DJ. Metabolic impact of sex hormones on obesity. Brain Research. 1350: 77-85. PMID 20441773 DOI: 10.1016/J.Brainres.2010.04.056 |
0.443 |
|
| 2010 |
Shi H, Sorrell JE, Clegg DJ, Woods SC, Seeley RJ. The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis. Physiology & Behavior. 100: 165-72. PMID 20193700 DOI: 10.1016/J.Physbeh.2010.02.018 |
0.413 |
|
| 2010 |
Davidson TL, Kanoski SE, Chan K, Clegg DJ, Benoit SC, Jarrard LE. Hippocampal lesions impair retention of discriminative responding based on energy state cues. Behavioral Neuroscience. 124: 97-105. PMID 20141284 DOI: 10.1037/A0018402 |
0.312 |
|
| 2010 |
Brown LM, Clegg DJ. Central effects of estradiol in the regulation of food intake, body weight, and adiposity. The Journal of Steroid Biochemistry and Molecular Biology. 122: 65-73. PMID 20035866 DOI: 10.1016/J.Jsbmb.2009.12.005 |
0.43 |
|
| 2010 |
Jessen L, Clegg DJ, Bouman SD. Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R43-50. PMID 19864335 DOI: 10.1152/Ajpregu.90736.2008 |
0.371 |
|
| 2010 |
Miller C, Clegg D, Cooney P, Brown L. Sex differences in diet-induced obesity and central leptin sensitivity in middle-aged rats Appetite. 54: 664. DOI: 10.1016/J.Appet.2010.04.141 |
0.366 |
|
| 2010 |
Miller C, Clegg D, Cooney P, Brown L. Proestrus rats have reduced inflammation and ER stress in the liver after 72h on a high fat diet Appetite. 54: 664. DOI: 10.1016/J.Appet.2010.04.140 |
0.308 |
|
| 2009 |
Nedungadi TP, Clegg DJ. Sexual dimorphism in body fat distribution and risk for cardiovascular diseases. Journal of Cardiovascular Translational Research. 2: 321-7. PMID 20560019 DOI: 10.1007/S12265-009-9101-1 |
0.411 |
|
| 2009 |
Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. The Journal of Clinical Investigation. 119: 2577-89. PMID 19726875 DOI: 10.1172/Jci36714 |
0.391 |
|
| 2009 |
Wang HH, Liu M, Clegg DJ, Portincasa P, Wang DQ. New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation. Biochimica Et Biophysica Acta. 1791: 1037-47. PMID 19589396 DOI: 10.1016/J.Bbalip.2009.06.006 |
0.344 |
|
| 2009 |
Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes. 58: 2292-302. PMID 19587358 DOI: 10.2337/Db09-0257 |
0.319 |
|
| 2009 |
Medvedovic M, Gear R, Freudenberg JM, Schneider J, Bornschein R, Yan M, Mistry MJ, Hendrix H, Karyala S, Halbleib D, Heffelfinger S, Clegg DJ, Anderson MW. Influence of fatty acid diets on gene expression in rat mammary epithelial cells. Physiological Genomics. 38: 80-8. PMID 19351911 DOI: 10.1152/Physiolgenomics.00007.2009 |
0.309 |
|
| 2009 |
Shi H, Seeley RJ, Clegg DJ. Sexual differences in the control of energy homeostasis. Frontiers in Neuroendocrinology. 30: 396-404. PMID 19341761 DOI: 10.1016/J.Yfrne.2009.03.004 |
0.4 |
|
| 2009 |
Shi H, Clegg DJ. Sex differences in the regulation of body weight. Physiology & Behavior. 97: 199-204. PMID 19250944 DOI: 10.1016/J.Physbeh.2009.02.017 |
0.422 |
|
| 2009 |
Haas E, Bhattacharya I, Brailoiu E, Damjanović M, Brailoiu GC, Gao X, Mueller-Guerre L, Marjon NA, Gut A, Minotti R, Meyer MR, Amann K, Ammann E, Perez-Dominguez A, Genoni M, ... Clegg DJ, et al. Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circulation Research. 104: 288-91. PMID 19179659 DOI: 10.1161/Circresaha.108.190892 |
0.323 |
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| 2009 |
Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. 296: E1003-12. PMID 19116375 DOI: 10.1152/Ajpendo.90377.2008 |
0.431 |
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| 2009 |
Davidson TL, Chan K, Jarrard LE, Kanoski SE, Clegg DJ, Benoit SC. Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation. Hippocampus. 19: 235-52. PMID 18831000 DOI: 10.1002/Hipo.20499 |
0.347 |
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| 2009 |
Shertzer HG, Schneider SN, Kendig EL, Clegg DJ, D'Alessio DA, Johansson E, Genter MB. Tetrahydroindenoindole inhibits the progression of diabetes in mice. Chemico-Biological Interactions. 177: 71-80. PMID 18823964 DOI: 10.1016/J.Cbi.2008.09.001 |
0.378 |
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| 2009 |
Ford J, Hajibeigi A, Getachew M, Liu J, Clegg D, Oz O. Loss of function of the non-genomic estrogen receptor GPR30 causes increased body size, percent body fat, and bone mass in adult male mice Bone. 44: S62-S63. DOI: 10.1016/J.Bone.2009.01.030 |
0.345 |
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| 2009 |
Brown L, Cooney P, Miller C, Clegg D. Proestrus rats on a high-fat diet have less central inflammation than male rats Appetite. 52: 821. DOI: 10.1016/J.Appet.2009.04.031 |
0.33 |
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| 2008 |
Davis JF, Tracy AL, Schurdak JD, Tschöp MH, Lipton JW, Clegg DJ, Benoit SC. Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behavioral Neuroscience. 122: 1257-63. PMID 19045945 DOI: 10.1037/A0013111 |
0.38 |
|
| 2008 |
Benoit SC, Tracy AL, Davis JF, Choi D, Clegg DJ. Novel functions of orexigenic hypothalamic peptides: from genes to behavior. Nutrition (Burbank, Los Angeles County, Calif.). 24: 843-7. PMID 18725081 DOI: 10.1016/J.Nut.2008.06.028 |
0.331 |
|
| 2008 |
Shen L, Tso P, Woods SC, Clegg DJ, Barber KL, Carey K, Liu M. Brain apolipoprotein E: an important regulator of food intake in rats. Diabetes. 57: 2092-8. PMID 18559657 DOI: 10.2337/Db08-0291 |
0.424 |
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| 2008 |
Kendig EL, Schneider SN, Clegg DJ, Genter MB, Shertzer HG. Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet. Biochemical Pharmacology. 76: 216-24. PMID 18554574 DOI: 10.1016/J.Bcp.2008.05.001 |
0.377 |
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| 2008 |
Shertzer HG, Schneider SN, Kendig EL, Clegg DJ, D'Alessio DA, Genter MB. Acetaminophen normalizes glucose homeostasis in mouse models for diabetes. Biochemical Pharmacology. 75: 1402-10. PMID 18237716 DOI: 10.1016/J.Bcp.2007.12.003 |
0.353 |
|
| 2008 |
Tracy AL, Clegg DJ, Johnson JD, Davidson TL, Benoit SC. The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer. Pharmacology, Biochemistry, and Behavior. 89: 263-71. PMID 18234306 DOI: 10.1016/J.Pbb.2007.12.018 |
0.422 |
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| 2008 |
Kemp CJ, D'Alessio DA, Scott RO, Kelm GR, Meller ST, Barrera JG, Seeley RJ, Clegg DJ, Benoit SC. Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. Physiology & Behavior. 93: 912-8. PMID 18234242 DOI: 10.1016/J.Physbeh.2007.12.008 |
0.394 |
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| 2008 |
Eric Hu X, Wos JA, Dowty ME, Suchanek PM, Ji W, Chambers JB, Benoit SC, Clegg DJ, Reizes O. Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight. The Journal of Pharmacology and Experimental Therapeutics. 324: 206-13. PMID 17932246 DOI: 10.1124/Jpet.107.130435 |
0.419 |
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| 2008 |
Reizes O, Benoit SC, Clegg DJ. The role of syndecans in the regulation of body weight and synaptic plasticity. The International Journal of Biochemistry & Cell Biology. 40: 28-45. PMID 17698399 DOI: 10.1016/J.Biocel.2007.06.011 |
0.371 |
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| 2008 |
Shen L, Tso P, Woods S, Clegg D, Barber K, Carey K, Liu M. Brain apolipoprotein E: An important regulator of food intake and body weight Appetite. 51: 399. DOI: 10.1016/J.Appet.2008.04.220 |
0.326 |
|
| 2008 |
Brown L, Clegg D, Benoit S, Woods S. Central administration of an NFκB antagonist prior to insulin reduces food intake and body weight in rats on a high-fat diet Appetite. 51: 356. DOI: 10.1016/J.Appet.2008.04.046 |
0.425 |
|
| 2007 |
Davidson TL, Kanoski SE, Schier LA, Clegg DJ, Benoit SC. A potential role for the hippocampus in energy intake and body weight regulation. Current Opinion in Pharmacology. 7: 613-6. PMID 18032108 DOI: 10.1016/J.Coph.2007.10.008 |
0.383 |
|
| 2007 |
Davis JF, Melhorn SJ, Shurdak JD, Heiman JU, Tschöp MH, Clegg DJ, Benoit SC. Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats. Physiology & Behavior. 92: 924-30. PMID 17689576 DOI: 10.1016/J.Physbeh.2007.06.024 |
0.364 |
|
| 2007 |
Musatov S, Chen W, Pfaff DW, Mobbs CV, Yang XJ, Clegg DJ, Kaplitt MG, Ogawa S. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proceedings of the National Academy of Sciences of the United States of America. 104: 2501-6. PMID 17284595 DOI: 10.1073/Pnas.0610787104 |
0.462 |
|
| 2007 |
Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N. Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes. 56: 1051-8. PMID 17251274 DOI: 10.2337/Db06-0015 |
0.425 |
|
| 2007 |
Brown LM, Benoit SC, Woods SC, Clegg DJ. Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats. Peptides. 28: 612-6. PMID 17196305 DOI: 10.1016/J.Peptides.2006.11.012 |
0.369 |
|
| 2007 |
Tracy A, Davis J, Heiman J, Schurdak J, Clegg D, Benoit S. Effect of high-fat diet-induced obesity on the efficacy of food and drug reinforcers. Appetite. 49: 335. DOI: 10.1016/J.Appet.2007.03.203 |
0.311 |
|
| 2007 |
Kemp C, Caldwell-lawson J, Clegg D, Benoit S. Interaction of MMP-3 and sex hormones in the control of energy balance. Appetite. 49: 303. DOI: 10.1016/J.Appet.2007.03.106 |
0.353 |
|
| 2007 |
Heiman J, Davis J, Tracy A, Moore R, Zigman J, Clegg D, Benoit S. Mice lacking the ghrelin receptor (GHS-R -/-) exhibit impaired hippocampal-dependent learning. Appetite. 49: 297. DOI: 10.1016/J.Appet.2007.03.087 |
0.326 |
|
| 2007 |
Choi D, Davis J, Clegg D, Benoit S. Mice exhibit enhanced macronutrient-specific conditioned place preference under hypocaloric conditions. Appetite. 49: 284. DOI: 10.1016/J.Appet.2007.03.048 |
0.351 |
|
| 2007 |
Chambers J, Schurdak J, Benoit S, Clegg D. Behavioral and metabolic phenotyping of GPR30 and neuronal estrogen receptor-α knockout mice. Appetite. 49: 283. DOI: 10.1016/J.Appet.2007.03.045 |
0.426 |
|
| 2007 |
Abplanalp W, Clegg D. Translocation of PKC theta by fatty acids causes hypothalamic insulin resistance. Appetite. 49: 274. DOI: 10.1016/J.Appet.2007.03.018 |
0.418 |
|
| 2006 |
Brown LM, Clegg DJ, Benoit SC, Woods SC. Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice. Physiology & Behavior. 89: 687-91. PMID 16979194 DOI: 10.1016/J.Physbeh.2006.08.008 |
0.448 |
|
| 2006 |
Clegg DJ, Brown LM, Woods SC, Benoit SC. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes. 55: 978-87. PMID 16567519 DOI: 10.2337/Diabetes.55.04.06.Db05-1339 |
0.388 |
|
| 2006 |
Gotoh K, Liu M, Benoit SC, Clegg DJ, Davidson WS, D'Alessio D, Seeley RJ, Tso P, Woods SC. Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R202-7. PMID 16166201 DOI: 10.1152/Ajpregu.00502.2005 |
0.324 |
|
| 2006 |
Woods SC, Benoit SC, Clegg DJ. The brain-gut-islet connection Diabetes. 55: S114-S121. DOI: 10.2337/Db06-S015 |
0.403 |
|
| 2006 |
Strader AD, Clegg DJ, Shi H, Chambers JB, Sorrell JE, Seeley RJ, Woods SC. WITHDRAWN: The leptin driven melanocortin pathway in the regulation of body fat and glucose homeostasis is sexually dimorphic Appetite. DOI: 10.1016/J.Appet.2006.03.291 |
0.355 |
|
| 2005 |
Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ. GM-CSF action in the CNS decreases food intake and body weight. The Journal of Clinical Investigation. 115: 3035-44. PMID 16276414 DOI: 10.1172/Jci25681 |
0.383 |
|
| 2005 |
Ogawa R, Strader AD, Clegg DJ, Sakai RR, Seeley RJ, Woods SC. Chronic food restriction and reduced dietary fat: risk factors for bouts of overeating. Physiology & Behavior. 86: 578-85. PMID 16176825 DOI: 10.1016/J.Physbeh.2005.08.028 |
0.384 |
|
| 2005 |
Benoit SC, Clegg DJ, Woods SC, Seeley RJ. The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides. Peptides. 26: 751-7. PMID 15808905 DOI: 10.1016/J.Peptides.2004.12.012 |
0.33 |
|
| 2005 |
Clegg DJ, Benoit SC, Reed JA, Woods SC, Dunn-Meynell A, Levin BE. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R981-6. PMID 15604298 DOI: 10.1152/Ajpregu.00675.2004 |
0.414 |
|
| 2004 |
Woods SC, D'Alessio DA, Tso P, Rushing PA, Clegg DJ, Benoit SC, Gotoh K, Liu M, Seeley RJ. Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiology & Behavior. 83: 573-8. PMID 15621062 DOI: 10.1016/J.Physbeh.2004.07.026 |
0.417 |
|
| 2004 |
Woods SC, Benoit SC, Clegg DJ, Seeley RJ. Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. Best Practice & Research. Clinical Endocrinology & Metabolism. 18: 497-515. PMID 15533772 DOI: 10.1016/J.Beem.2004.08.004 |
0.412 |
|
| 2004 |
Seeley RJ, Drazen DL, Clegg DJ. The critical role of the melanocortin system in the control of energy balance. Annual Review of Nutrition. 24: 133-49. PMID 15189116 DOI: 10.1146/Annurev.Nutr.24.012003.132428 |
0.385 |
|
| 2004 |
Benoit SC, Clegg DJ, Seeley RJ, Woods SC. Insulin and leptin as adiposity signals. Recent Progress in Hormone Research. 59: 267-85. PMID 14749506 DOI: 10.1210/Rp.59.1.267 |
0.402 |
|
| 2003 |
Drazen DL, Wortman MD, Schwartz MW, Clegg DJ, van Dijk G, Woods SC, Seeley RJ. Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. Diabetes. 52: 2928-34. PMID 14633853 DOI: 10.2337/Diabetes.52.12.2928 |
0.421 |
|
| 2003 |
Woods SC, Gotoh K, Clegg DJ. Gender differences in the control of energy homeostasis. Experimental Biology and Medicine (Maywood, N.J.). 228: 1175-80. PMID 14610257 DOI: 10.1177/153537020322801012 |
0.435 |
|
| 2003 |
Benoit SC, Clegg DJ, Barrera JG, Seeley RJ, Woods SC. Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. Diabetes. 52: 2684-8. PMID 14578286 DOI: 10.2337/Diabetes.52.11.2684 |
0.395 |
|
| 2003 |
Reizes O, Benoit SC, Strader AD, Clegg DJ, Akunuru S, Seeley RJ. Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway. Annals of the New York Academy of Sciences. 994: 66-73. PMID 12851299 DOI: 10.1111/J.1749-6632.2003.Tb03163.X |
0.391 |
|
| 2003 |
Clegg DJ, Benoit SC, Air EL, Jackman A, Tso P, D'Alessio D, Woods SC, Seeley RJ. Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology. 144: 2941-6. PMID 12810549 DOI: 10.1210/En.2002-0218 |
0.432 |
|
| 2003 |
Benoit SC, McQuade JA, Clegg DJ, Xu M, Rushing PA, Woods SC, Seeley RJ. Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. Behavioral Neuroscience. 117: 46-54. PMID 12619907 DOI: 10.1037/0735-7044.117.1.46 |
0.387 |
|
| 2003 |
Clegg DJ, Riedy CA, Smith KA, Benoit SC, Woods SC. Differential sensitivity to central leptin and insulin in male and female rats. Diabetes. 52: 682-7. PMID 12606509 DOI: 10.2337/Diabetes.52.3.682 |
0.39 |
|
| 2003 |
Clegg DJ, Edwards GL, Martin RJ. Central insulin potentiates eating elicited by 2-deoxy-D-glucose. Physiology & Behavior. 78: 331-6. PMID 12576132 DOI: 10.1016/S0031-9384(02)01000-4 |
0.372 |
|
| 2003 |
Clegg DJ, Air EL, Benoit SC, Sakai RS, Seeley RJ, Woods SC. Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R494-9. PMID 12557891 DOI: 10.1152/Ajpregu.00399.2002 |
0.316 |
|
| 2003 |
Niswender KD, Morrison CD, Clegg DJ, Olson R, Baskin DG, Myers MG, Seeley RJ, Schwartz MW. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 52: 227-31. PMID 12540590 DOI: 10.2337/Diabetes.52.2.227 |
0.355 |
|
| 2002 |
Clegg DJ, Wortman MD, Benoit SC, McOsker CC, Seeley RJ. Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes. 51: 3196-201. PMID 12401710 DOI: 10.2337/Diabetes.51.11.3196 |
0.363 |
|
| 2002 |
Brugman S, Clegg DJ, Woods SC, Seeley RJ. Combined blockade of both micro - and kappa-opioid receptors prevents the acute orexigenic action of Agouti-related protein. Endocrinology. 143: 4265-70. PMID 12399421 DOI: 10.1210/En.2002-220230 |
0.326 |
|
| 2002 |
Benoit SC, Air EL, Coolen LM, Strauss R, Jackman A, Clegg DJ, Seeley RJ, Woods SC. The catabolic action of insulin in the brain is mediated by melanocortins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9048-52. PMID 12388611 DOI: 10.1523/Jneurosci.22-20-09048.2002 |
0.396 |
|
| 2002 |
Clegg DJ, Air EL, Woods SC, Seeley RJ. Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated. Endocrinology. 143: 2995-3000. PMID 12130565 DOI: 10.1210/Endo.143.8.8977 |
0.364 |
|
| 2002 |
Air EL, Benoit SC, Clegg DJ, Seeley RJ, Woods SC. Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology. 143: 2449-52. PMID 12021212 DOI: 10.1210/Endo.143.6.8948 |
0.419 |
|
| 2002 |
Air EL, Benoit SC, Blake Smith KA, Clegg DJ, Woods SC. Acute third ventricular administration of insulin decreases food intake in two paradigms. Pharmacology, Biochemistry, and Behavior. 72: 423-9. PMID 11900815 DOI: 10.1016/S0091-3057(01)00780-8 |
0.385 |
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