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Brian S. Freeze, Ph.D. - Publications

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Natural product synthesis
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Smith AB, Freeze BS. (+)-Discodermolide: Total Synthesis, Construction of Novel Analogues, and Biological Evaluation. Tetrahedron. 64: 261-298. PMID 21113402 DOI: 10.1016/j.tet.2007.10.039  0.375
2007 Jenkins TJ, Guan B, Dai M, Li G, Lightburn TE, Huang S, Freeze BS, Burdi DF, Jacutin-Porte S, Bennett R, Chen W, Minor C, Ghosh S, Blackburn C, Gigstad KM, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. Journal of Medicinal Chemistry. 50: 566-84. PMID 17266208 DOI: 10.1021/jm061118e  0.376
2005 Smith AB, Rucker PV, Brouard I, Freeze BS, Xia S, Horwitz SB. Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes. Organic Letters. 7: 5199-202. PMID 16268537 DOI: 10.1021/ol0520166  0.301
2005 Smith AB, Freeze BS, LaMarche MJ, Sager J, Kinzler KW, Vogelstein B. Discodermolide analogues as the chemical component of combination bacteriolytic therapy. Bioorganic & Medicinal Chemistry Letters. 15: 3623-6. PMID 15979874 DOI: 10.1016/J.Bmcl.2005.05.068  0.517
2005 Shaw SJ, Sundermann KF, Burlingame MA, Myles DC, Freeze BS, Xian M, Brouard I, Smith AB. Toward understanding how the lactone moiety of discodermolide affects activity. Journal of the American Chemical Society. 127: 6532-3. PMID 15869264 DOI: 10.1021/Ja051185I  0.511
2005 Smith AB, Freeze BS, Xian M, Hirose T. Total synthesis of (+)-discodermolide: a highly convergent fourth-generation approach. Organic Letters. 7: 1825-8. PMID 15844916 DOI: 10.1021/Ol050455Z  0.519
2005 Smith AB, Freeze BS, Lamarche MJ, Hirose T, Brouard I, Xian M, Sundermann KF, Shaw SJ, Burlingame MA, Horwitz SB, Myles DC. Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide. Organic Letters. 7: 315-8. PMID 15646986 DOI: 10.1021/Ol0476873  0.58
2005 Smith AB, Freeze BS, Lamarche MJ, Hirose T, Brouard I, Rucker PV, Xian M, Sundermann KF, Shaw SJ, Burlingame MA, Horwitz SB, Myles DC. Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide. Organic Letters. 7: 311-4. PMID 15646985 DOI: 10.1021/Ol047686A  0.584
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