W Scott Young, M.D., Ph.D. - Publications

Affiliations: 
Section on Neural Gene Expression NIMH, NIH, Bethesda, MD, Bethesda, MD, United States 
Area:
oxytocin, vasopressin, behavior
Website:
http://www.nimh.nih.gov/labs-at-nimh/research-areas/clinics-and-labs/lcmr/snge/index.shtml

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cymerblit-Sabba A, Smith AS, Williams Avram SK, Stackmann M, Korgan AC, Tickerhoof MC, Young WS. Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Frontiers in Molecular Neuroscience. 13: 61. PMID 32390799 DOI: 10.3389/fnmol.2020.00061  0.638
2019 Williams Avram SK, Lee HJ, Fastman J, Cymerblit-Sabba A, Smith A, Vincent M, Song J, Granovetter MC, Lee SH, Cilz NI, Stackmann M, Chaturvedi R, Young WS. NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression. Frontiers in Behavioral Neuroscience. 13: 218. PMID 31787886 DOI: 10.3389/Fnbeh.2019.00218  0.721
2019 Smith AS, Korgan AC, Young WS. Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice. Pharmacological Research. 104324. PMID 31238093 DOI: 10.1016/j.phrs.2019.104324  0.608
2018 Cilz NI, Cymerblit-Sabba A, Young WS. Oxytocin and Vasopressin in the Rodent Hippocampus. Genes, Brain, and Behavior. e12535. PMID 30378258 DOI: 10.1111/gbb.12535  0.432
2017 Mayer B, Németh K, Krepuska M, Myneni VD, Maric D, Tisdale JF, Hsieh MM, Uchida N, Lee HJ, Nemeth MJ, Holmbeck K, Noguchi CT, Rogers H, Dey S, Hansen A, ... ... Young WS, et al. Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia. Science Translational Medicine. 9. PMID 29187641 DOI: 10.1126/Scitranslmed.Aao1632  0.763
2016 Patial S, Stumpo DJ, Young WS, Ward JM, Flake GP, Blackshear PJ. Effects of combined tristetraprolin/tumor necrosis factor receptor deficiency on the splenic transcriptome. Molecular and Cellular Biology. PMID 26976640 DOI: 10.1128/Mcb.01068-15  0.357
2016 Smith AS, Williams Avram SK, Cymerblit-Sabba A, Song J, Young WS. Targeted activation of the hippocampal CA2 area strongly enhances social memory. Molecular Psychiatry. PMID 26728562 DOI: 10.1038/mp.2015.189  0.544
2015 Pagani JH, Williams Avram SK, Cui Z, Song J, Mezey É, Senerth JM, Baumann MH, Young WS. Raphe serotonin neuron-specific oxytocin receptor knockout reduces aggression without affecting anxiety-like behavior in male mice only. Genes, Brain, and Behavior. 14: 167-76. PMID 25677455 DOI: 10.1111/gbb.12202  0.787
2015 Pagani JH, Zhao M, Cui Z, Avram SK, Caruana DA, Dudek SM, Young WS. Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2. Molecular Psychiatry. 20: 490-9. PMID 24863146 DOI: 10.1038/mp.2014.47  0.8
2013 Young WS. Shedding heat on oxytocin. Endocrinology. 154: 3961-2. PMID 24141993 DOI: 10.1210/en.2013-1885  0.307
2013 Choi JW, Kang SM, Lee Y, Hong SH, Sanek NA, Young WS, Lee HJ. MicroRNA profiling in the mouse hypothalamus reveals oxytocin-regulating microRNA. Journal of Neurochemistry. 126: 331-7. PMID 23682839 DOI: 10.1111/Jnc.12308  0.613
2012 Colaianni G, Sun L, Di Benedetto A, Tamma R, Zhu LL, Cao J, Grano M, Yuen T, Colucci S, Cuscito C, Mancini L, Li J, Nishimori K, Bab I, Lee HJ, ... ... Young WS, et al. Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton. The Journal of Biological Chemistry. 287: 29159-67. PMID 22761429 DOI: 10.1074/Jbc.M112.365049  0.635
2012 Pobbe RL, Pearson BL, Defensor EB, Bolivar VJ, Young WS, Lee HJ, Blanchard DC, Blanchard RJ. Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors. Hormones and Behavior. 61: 436-44. PMID 22100185 DOI: 10.1016/J.Yhbeh.2011.10.010  0.74
2012 Malkesman O, Austin DR, Tragon T, Wang G, Rompala G, Hamidi AB, Cui Z, Young WS, Nakazawa K, Zarate CA, Manji HK, Chen G. Acute D-serine treatment produces antidepressant-like effects in rodents. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1135-48. PMID 21906419 DOI: 10.1017/S1461145711001386  0.318
2012 Mok SI, Munasinghe JP, Young WS. Infusion-based manganese-enhanced MRI: a new imaging technique to visualize the mouse brain. Brain Structure & Function. 217: 107-14. PMID 21597966 DOI: 10.1007/s00429-011-0324-y  0.747
2011 Pagani JH, Lee HJ, Young WS. Postweaning, forebrain-specific perturbation of the oxytocin system impairs fear conditioning. Genes, Brain, and Behavior. 10: 710-9. PMID 21668734 DOI: 10.1111/j.1601-183X.2011.00709.x  0.819
2011 Roper J, O'Carroll AM, Young W, Lolait S. The vasopressin Avpr1b receptor: molecular and pharmacological studies. Stress (Amsterdam, Netherlands). 14: 98-115. PMID 20828336 DOI: 10.3109/10253890.2010.512376  0.341
2011 Pagani JH, Wersinger SR, Young WS. The roles of vasopressin and oxytocin in aggression Oxytocin, Vasopressin, and Related Peptides in the Regulation of Behavior. 193-212. DOI: 10.1017/CBO9781139017855.014  0.768
2010 Macbeth AH, Stepp JE, Lee HJ, Young WS, Caldwell HK. Normal maternal behavior, but increased pup mortality, in conditional oxytocin receptor knockout females. Behavioral Neuroscience. 124: 677-85. PMID 20939667 DOI: 10.1037/A0020799  0.782
2010 Lee HJ, Pagani J, Young WS. Using transgenic mouse models to study oxytocin's role in the facilitation of species propagation. Brain Research. 1364: 216-24. PMID 20732312 DOI: 10.1016/J.Brainres.2010.08.042  0.813
2010 Caldwell HK, Dike OE, Stevenson EL, Storck K, Young WS. Social dominance in male vasopressin 1b receptor knockout mice. Hormones and Behavior. 58: 257-63. PMID 20298692 DOI: 10.1016/J.Yhbeh.2010.03.008  0.826
2010 Katoh A, Fujihara H, Ohbuchi T, Onaka T, Young WS, Dayanithi G, Yamasaki Y, Kawata M, Suzuki H, Otsubo H, Suzuki H, Murphy D, Ueta Y. Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary. The Journal of Endocrinology. 204: 275-85. PMID 20026620 DOI: 10.1677/Joe-09-0289  0.334
2009 Macbeth AH, Edds JS, Young WS. Housing conditions and stimulus females: a robust social discrimination task for studying male rodent social recognition. Nature Protocols. 4: 1574-81. PMID 19816420 DOI: 10.1038/nprot.2009.141  0.381
2009 Lee HJ, Macbeth AH, Pagani JH, Young WS. Oxytocin: the great facilitator of life. Progress in Neurobiology. 88: 127-51. PMID 19482229 DOI: 10.1016/J.Pneurobio.2009.04.001  0.804
2009 Caldwell HK, Young WS. Persistence of reduced aggression in vasopressin 1b receptor knockout mice on a more "wild" background. Physiology & Behavior. 97: 131-4. PMID 19419666 DOI: 10.1016/J.Physbeh.2009.02.006  0.745
2009 DeVito LM, Konigsberg R, Lykken C, Sauvage M, Young WS, Eichenbaum H. Vasopressin 1b receptor knock-out impairs memory for temporal order. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2676-83. PMID 19261862 DOI: 10.1523/Jneurosci.5488-08.2009  0.454
2009 Caldwell HK, Stephens SL, Young WS. Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice. Molecular Psychiatry. 14: 190-6. PMID 18227836 DOI: 10.1038/Sj.Mp.4002150  0.676
2008 Lee HJ, Caldwell HK, Macbeth AH, Young WS. Behavioural studies using temporal and spatial inactivation of the oxytocin receptor. Progress in Brain Research. 170: 73-7. PMID 18655873 DOI: 10.1016/S0079-6123(08)00407-X  0.803
2008 Caldwell HK, Wersinger SR, Young WS. The role of the vasopressin 1b receptor in aggression and other social behaviours. Progress in Brain Research. 170: 65-72. PMID 18655872 DOI: 10.1016/S0079-6123(08)00406-8  0.821
2008 Lee HJ, Caldwell HK, Macbeth AH, Tolu SG, Young WS. A conditional knockout mouse line of the oxytocin receptor. Endocrinology. 149: 3256-63. PMID 18356275 DOI: 10.1210/En.2007-1710  0.826
2008 Stewart LQ, Roper JA, Young WS, O'Carroll AM, Lolait SJ. The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants. Psychoneuroendocrinology. 33: 405-15. PMID 18243568 DOI: 10.1016/j.psyneuen.2007.12.009  0.414
2008 Caldwell HK, Lee HJ, Macbeth AH, Young WS. Vasopressin: behavioral roles of an "original" neuropeptide. Progress in Neurobiology. 84: 1-24. PMID 18053631 DOI: 10.1016/J.Pneurobio.2007.10.007  0.804
2008 Scattoni ML, McFarlane HG, Zhodzishsky V, Caldwell HK, Young WS, Ricceri L, Crawley JN. Reduced ultrasonic vocalizations in vasopressin 1b knockout mice. Behavioural Brain Research. 187: 371-8. PMID 18005969 DOI: 10.1016/J.Bbr.2007.09.034  0.722
2008 Wersinger SR, Temple JL, Caldwell HK, Young WS. Inactivation of the oxytocin and the vasopressin (Avp) 1b receptor genes, but not the Avp 1a receptor gene, differentially impairs the Bruce effect in laboratory mice (Mus musculus). Endocrinology. 149: 116-21. PMID 17947352 DOI: 10.1210/En.2007-1056  0.796
2007 Yang M, Scattoni ML, Zhodzishsky V, Chen T, Caldwell H, Young WS, McFarlane HG, Crawley JN. Social approach behaviors are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+ tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice. Frontiers in Behavioral Neuroscience. 1: 1. PMID 18958184 DOI: 10.3389/Neuro.08.001.2007  0.701
2007 Crawley JN, Chen T, Puri A, Washburn R, Sullivan TL, Hill JM, Young NB, Nadler JJ, Moy SS, Young LJ, Caldwell HK, Young WS. Social approach behaviors in oxytocin knockout mice: comparison of two independent lines tested in different laboratory environments. Neuropeptides. 41: 145-63. PMID 17420046 DOI: 10.1016/J.Npep.2007.02.002  0.723
2007 Wersinger SR, Caldwell HK, Christiansen M, Young WS. Disruption of the vasopressin 1b receptor gene impairs the attack component of aggressive behavior in mice. Genes, Brain, and Behavior. 6: 653-60. PMID 17284170 DOI: 10.1111/J.1601-183X.2006.00294.X  0.819
2007 Wersinger SR, Caldwell HK, Martinez L, Gold P, Hu SB, Young WS. Vasopressin 1a receptor knockout mice have a subtle olfactory deficit but normal aggression. Genes, Brain, and Behavior. 6: 540-51. PMID 17083331 DOI: 10.1111/J.1601-183X.2006.00281.X  0.832
2006 Caldwell HK, Stewart J, Wiedholz LM, Millstein RA, Iacangelo A, Holmes A, Young WS, Wersinger SR. The acute intoxicating effects of ethanol are not dependent on the vasopressin 1a or 1b receptors. Neuropeptides. 40: 325-37. PMID 17049983 DOI: 10.1016/J.Npep.2006.08.001  0.776
2006 Lee HJ, Palkovits M, Young WS. miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation. Proceedings of the National Academy of Sciences of the United States of America. 103: 15669-74. PMID 17028171 DOI: 10.1073/Pnas.0605781103  0.627
2006 Young WS, Li J, Wersinger SR, Palkovits M. The vasopressin 1b receptor is prominent in the hippocampal area CA2 where it is unaffected by restraint stress or adrenalectomy. Neuroscience. 143: 1031-9. PMID 17027167 DOI: 10.1016/J.Neuroscience.2006.08.040  0.745
2006 Caldwell HK, Martinez L, Hu S, Young WS, Wersinger SR. Vasopressin 1a receptor knockout mice have altered circadian rhythm and olfaction Frontiers in Neuroendocrinology. 27: 126. DOI: 10.1016/J.Yfrne.2006.03.327  0.795
2004 Wersinger SR, Kelliher KR, Zufall F, Lolait SJ, O'Carroll AM, Young WS. Social motivation is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination task. Hormones and Behavior. 46: 638-45. PMID 15555506 DOI: 10.1016/J.Yhbeh.2004.07.004  0.731
2002 Hollon TR, Bek MJ, Lachowicz JE, Ariano MA, Mezey E, Ramachandran R, Wersinger SR, Soares-da-Silva P, Liu ZF, Grinberg A, Drago J, Young WS, Westphal H, Jose PA, Sibley DR. Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10801-10. PMID 12486173 DOI: 10.1523/Jneurosci.22-24-10801.2002  0.722
2002 Wersinger SR, Ginns EI, O'Carroll AM, Lolait SJ, Young WS. Vasopressin V1b receptor knockout reduces aggressive behavior in male mice. Molecular Psychiatry. 7: 975-84. PMID 12399951 DOI: 10.1038/sj.mp.4001195  0.755
2002 Hamelink C, Tjurmina O, Damadzic R, Young WS, Weihe E, Lee HW, Eiden LE. Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 461-6. PMID 11756684 DOI: 10.1073/pnas.012608999  0.589
1998 Young WS, Shepard E, DeVries AC, Zimmer A, LaMarca ME, Ginns EI, Amico J, Nelson RJ, Hennighausen L, Wagner KU. Targeted reduction of oxytocin expression provides insights into its physiological roles. Advances in Experimental Medicine and Biology. 449: 231-40. PMID 10026810 DOI: 10.1007/978-1-4615-4871-3_30  0.446
1998 Lautens LL, Chiou XG, Sharp JD, Young WS, Sprague DL, Ross LS, Felder CC. Cytosolic phospholipase A2 (cPLA2) distribution in murine brain and functional studies indicate that cPLA2 does not participate in muscarinic receptor-mediated signaling in neurons. Brain Research. 809: 18-30. PMID 9795110 DOI: 10.1016/S0006-8993(98)00806-3  0.375
1997 Chawla MK, Gutierrez GM, Young WS, McMullen NT, Rance NE. Localization of neurons expressing substance P and neurokinin B gene transcripts in the human hypothalamus and basal forebrain. The Journal of Comparative Neurology. 384: 429-42. PMID 9254037 DOI: 10.1002/(Sici)1096-9861(19970804)384:3<429::Aid-Cne8>3.0.Co;2-5  0.309
1997 Wang X, Brownstein MJ, Young WS. PG25, a pineal-specific cDNA, cloned by differential display PCR (DDPCR) and rapid amplification of cDNA ends (RACE). Journal of Neuroscience Methods. 73: 187-91. PMID 9196290 DOI: 10.1016/S0165-0270(97)02237-1  0.492
1997 DeVries AC, Young WS, Nelson RJ. Reduced aggressive behaviour in mice with targeted disruption of the oxytocin gene. Journal of Neuroendocrinology. 9: 363-8. PMID 9181490 DOI: 10.1046/J.1365-2826.1997.T01-1-00589.X  0.472
1996 Young WS, Shepard E, Amico J, Hennighausen L, Wagner KU, LaMarca ME, McKinney C, Ginns EI. Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition. Journal of Neuroendocrinology. 8: 847-53. PMID 8933362 DOI: 10.1046/J.1365-2826.1996.05266.X  0.417
1996 Wang X, Brownstein MJ, Young WS. Sequence analysis of PG10.2, a gene expressed in the pineal gland and the outer nuclear layer of the retina. Brain Research. Molecular Brain Research. 41: 269-78. PMID 8883960 DOI: 10.1016/0169-328X(96)00107-6  0.459
1995 Aguilera G, Young WS, Kiss A, Bathia A. Direct regulation of hypothalamic corticotropin-releasing-hormone neurons by angiotensin II. Neuroendocrinology. 61: 437-44. PMID 7783857 DOI: 10.1159/000126866  0.384
1995 Lolait SJ, O'Carroll AM, Mahan LC, Felder CC, Button DC, Young WS, Mezey E, Brownstein MJ. Extrapituitary expression of the rat V1b vasopressin receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 6783-7. PMID 7624319 DOI: 10.1073/Pnas.92.15.6783  0.503
1994 Rance NE, Young WS, McMullen NT. Topography of neurons expressing luteinizing hormone-releasing hormone gene transcripts in the human hypothalamus and basal forebrain. The Journal of Comparative Neurology. 339: 573-86. PMID 8144747 DOI: 10.1002/Cne.903390408  0.33
1994 Song ZH, Young WS, Brownstein MJ, Bonner TI. Molecular cloning of a novel candidate G protein-coupled receptor from rat brain. Febs Letters. 351: 375-9. PMID 8082799 DOI: 10.1016/0014-5793(94)00888-4  0.523
1993 Sukhov RR, Walker LC, Rance NE, Price DL, Young WS. Vasopressin and oxytocin gene expression in the human hypothalamus. The Journal of Comparative Neurology. 337: 295-306. PMID 8277003 DOI: 10.1002/Cne.903370210  0.305
1992 Ostrowski NL, Lolait SJ, Bradley DJ, O'Carroll AM, Brownstein MJ, Young WS. Distribution of V1a and V2 vasopressin receptor messenger ribonucleic acids in rat liver, kidney, pituitary and brain. Endocrinology. 131: 533-5. PMID 1535312 DOI: 10.1210/endo.131.1.1535312  0.458
1992 Belenky M, Castel M, Young WS, Gainer H, Cohen S. Ultrastructural immunolocalization of rat oxytocin-neurophysin in transgenic mice expressing the rat oxytocin gene. Brain Research. 583: 279-86. PMID 1504834 DOI: 10.1016/S0006-8993(10)80034-4  0.346
1992 Young WS, Lightman SL. Chronic stress elevates enkephalin expression in the rat paraventricular and supraoptic nuclei. Brain Research. Molecular Brain Research. 13: 111-7. PMID 1349719 DOI: 10.1016/0169-328X(92)90050-L  0.311
1991 Rance NE, Young WS. Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women. Endocrinology. 128: 2239-47. PMID 1708331 DOI: 10.1210/Endo-128-5-2239  0.324
1990 Young WS, Reynolds K, Shepard EA, Gainer H, Castel M. Cell-specific expression of the rat oxytocin gene in transgenic mice. Journal of Neuroendocrinology. 2: 917-25. PMID 19215438 DOI: 10.1111/j.1365-2826.1990.tb00660.x  0.381
1989 Grino M, Young WS, Burgunder JM. Ontogeny of expression of the corticotropin-releasing factor gene in the hypothalamic paraventricular nucleus and of the proopiomelanocortin gene in rat pituitary. Endocrinology. 124: 60-8. PMID 2783310 DOI: 10.1210/ENDO-124-1-60  0.3
1989 Burgunder JM, Young WS. Ontogeny of cholecystokinin gene expression in the rat thalamus--a hybridization histochemical study. Brain Research. Developmental Brain Research. 46: 221-32. PMID 2720955 DOI: 10.1016/0165-3806(89)90286-1  0.3
1987 Powers RE, DeSouza EB, Walker LC, Price DL, Vale WW, Young WS. Corticotropin-releasing factor as a transmitter in the human olivocerebellar pathway. Brain Research. 415: 347-52. PMID 2886191 DOI: 10.1016/0006-8993(87)90218-6  0.341
1981 Young WS, Kuhar MJ. Neurotensin receptor localization by light microscopic autoradiography in rat brain Brain Research. 206: 273-285. PMID 6260280 DOI: 10.1016/0006-8993(81)90532-1  0.515
1980 Young WS, Kuhar MJ. alpha 2-Adrenergic receptors are associated with renal proximal tubules European Journal of Pharmacology. 67: 493-495. PMID 6256180 DOI: 10.1016/0014-2999(80)90194-6  0.47
1980 Wamsley JK, Young WS, Kuhar MJ. Immunohistochemical localization of enkephalin in rat forebrain. Brain Research. 190: 153-74. PMID 6247008 DOI: 10.1016/0006-8993(80)91166-X  0.465
1980 Palacios JM, Young WS, Kuhar MJ. Autoradiographic localization of H1-histamine receptors in brain using 3H-mepyramine: preliminary studies. European Journal of Pharmacology. 58: 295-304. PMID 510360 DOI: 10.1016/0014-2999(79)90478-3  0.498
1980 Young W, Kuhar MJ, Roth J, Brownstein MJ. Radiohistochemical localization of insulin receptors in the adult and developing rat brain Neuropeptides. 1: 15-22. DOI: 10.1016/0143-4179(80)90004-9  0.601
1979 Young WS, Kuhar MJ. Autoradiographic localisation of benzodiazepine receptors in the brains of humans and animals [11] Nature. 280: 393-395. DOI: 10.1038/280393a0  0.528
1979 Kuhar MJ, Palacios JM, Young W. Radiohistochemical studies of the GABA and beiizodiazepine (BZ) receptors Brain Research Bulletin. 4: 700. DOI: 10.1016/0361-9230(79)90207-7  0.462
1978 Young WS, Uhl GR, Kuhar MJ. Iontophoresis of neurotensin in the area of the locus coeruleus. Brain Research. 150: 431-5. PMID 678982 DOI: 10.1016/0006-8993(78)90296-2  0.424
1977 Young WS, Bird SJ, Kuhar MJ. Iontophoresis of methionine-enkephalin in the locus coeruleus area. Brain Research. 129: 366-70. PMID 884509 DOI: 10.1016/0006-8993(77)90017-8  0.427
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