K Jane Grande-Allen - Publications

Affiliations: 
Rice University, Houston, TX 
Area:
Biomedical Engineering, Biomechanics Biophysics

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vukicevic M, Mehta SM, Grande-Allen KJ, Little SH. Development of 3D Printed Mitral Valve Constructs for Transcatheter Device Modeling of Tissue and Device Deformation. Annals of Biomedical Engineering. PMID 35220528 DOI: 10.1007/s10439-022-02927-y  0.309
2021 Zhu AS, Mustafa T, Connell JP, Grande-Allen KJ. Tumor necrosis factor alpha and interleukin 1 beta suppress myofibroblast activation via nuclear factor kappa B signaling in 3D-cultured mitral valve interstitial cells. Acta Biomaterialia. PMID 33831572 DOI: 10.1016/j.actbio.2021.03.075  0.338
2020 Chester AH, Grande-Allen KJ. Which Biological Properties of Heart Valves Are Relevant to Tissue Engineering? Frontiers in Cardiovascular Medicine. 7: 63. PMID 32373630 DOI: 10.3389/Fcvm.2020.00063  0.564
2020 Wilson RL, Sylvester CB, Wiltz DC, Kumar A, Malik TH, Morrisett JD, Grande-Allen KJ. The Ryanodine Receptor Contributes to the Lysophosphatidylcholine-Induced Mineralization in Valvular Interstitial Cells. Cardiovascular Engineering and Technology. PMID 32356274 DOI: 10.1007/S13239-020-00463-1  0.416
2019 Swaminathan G, Krishnamurthy VK, Sridhar S, Robson DC, Ning Y, Grande-Allen KJ. Hypoxia Stimulates Synthesis of Neutrophil Gelatinase-Associated Lipocalin in Aortic Valve Disease. Frontiers in Cardiovascular Medicine. 6: 156. PMID 31737648 DOI: 10.3389/Fcvm.2019.00156  0.53
2019 Smith BT, Bittner SM, Watson E, Smoak MM, Diaz-Gomez LA, Molina ER, Kim YS, Hudgins CD, Melchiorri AJ, Scott DW, Grande-Allen KJ, Yoo JJ, Atala A, Fisher JP, Mikos AG. Multi-Material Dual Gradient 3D Printing for Osteogenic Differentiation and Spatial Segregation. Tissue Engineering. Part A. PMID 31696784 DOI: 10.1089/Ten.Tea.2019.0204  0.315
2019 Monroe MN, Nikonowicz RC, Grande-Allen KJ. Heterogeneous multi-laminar tissue constructs as a platform to evaluate aortic valve matrix-dependent pathogenicity. Acta Biomaterialia. 97: 420-427. PMID 31362141 DOI: 10.1016/J.Actbio.2019.07.046  0.585
2019 Vekilov DP, Singh M, Aglyamov SR, Larin KV, Grande-Allen KJ. Mapping the spatial variation of mitral valve elastic properties using air-pulse optical coherence elastography. Journal of Biomechanics. PMID 31300156 DOI: 10.1016/J.Jbiomech.2019.06.015  0.475
2019 Smoak MM, Han A, Watson E, Kishan A, Grande-Allen KJ, Cosgriff-Hernandez E, Mikos AG. Fabrication and Characterization of Electrospun Decellularized Muscle-derived Scaffolds. Tissue Engineering. Part C, Methods. PMID 30909819 DOI: 10.1089/Ten.Tec.2018.0339  0.339
2019 Vekilov DP, Grande-Allen KJ. Mechanical Properties of Diseased Veins. Methodist Debakey Cardiovascular Journal. 14: 182-187. PMID 30410647 DOI: 10.14797/Mdcj-14-3-182  0.315
2019 Wilson RL, Connell JP, Grande-Allen KJ. Monitoring Oxygen Levels within Large, Tissue-Engineered Constructs Using Porphyin-Hydrogel Microparticles Acs Biomaterials Science & Engineering. 5: 4522-4530. DOI: 10.1021/Acsbiomaterials.9B00257  0.314
2018 Gomel MA, Lee R, Grande-Allen KJ. Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression. Frontiers in Cardiovascular Medicine. 5: 197. PMID 30687719 DOI: 10.3389/Fcvm.2018.00197  0.5
2018 Massé DD, Shar JA, Brown KN, Keswani SG, Grande-Allen KJ, Sucosky P. Discrete Subaortic Stenosis: Perspective Roadmap to a Complex Disease. Frontiers in Cardiovascular Medicine. 5: 122. PMID 30320123 DOI: 10.3389/Fcvm.2018.00122  0.34
2018 Sikes KJ, Renner K, Li J, Grande-Allen KJ, Connell JP, Cali V, Midura RJ, Sandy JD, Plaas A, Wang VM. Knockout of Hyaluronan Synthase 1, but not 3, Impairs Formation of the Retrocalcaneal Bursa. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29672913 DOI: 10.1002/Jor.24027  0.391
2018 Connell PS, Vekilov DP, Diaz CM, Kim SE, Grande-Allen KJ. Eliminating Regurgitation Reduces Fibrotic Remodeling of Functional Mitral Regurgitation Conditioned Valves. Annals of Biomedical Engineering. PMID 29404848 DOI: 10.1007/S10439-018-1987-9  0.527
2018 Zhu AS, Grande-Allen KJ. Heart valve tissue engineering for valve replacement and disease modeling Current Opinion in Biomedical Engineering. 5: 35-41. DOI: 10.1016/J.Cobme.2017.12.006  0.512
2017 Stephens EH, Han J, Trawick EA, Di Martino ES, Akkiraju H, Brown LM, Connell JP, Grande-Allen KJ, Vunjak-Novakovic G, Takayama H. Left-Ventricular Assist Device Impact on Aortic Valve Mechanics, Proteomics and Ultrastructure. The Annals of Thoracic Surgery. PMID 29223417 DOI: 10.1016/J.Athoracsur.2017.08.030  0.657
2016 Puperi DS, Kishan A, Punske ZE, Wu Y, Cosgriff-Hernandez E, West JL, Grande-Allen KJ. Electrospun Polyurethane and Hydrogel Composite Scaffolds as Biomechanical Mimics for Aortic Valve Tissue Engineering. Acs Biomaterials Science & Engineering. 2: 1546-1558. PMID 33440590 DOI: 10.1021/acsbiomaterials.6b00309  0.499
2016 Wu Y, Grande-Allen KJ, West JL. Adhesive Peptide Sequences Regulate Valve Interstitial Cell Adhesion, Phenotype and Extracellular Matrix Deposition. Cellular and Molecular Bioengineering. 9: 479-495. PMID 28220141 DOI: 10.1007/S12195-016-0451-X  0.381
2016 Sapp MC, Krishnamurthy VK, Puperi DS, Bhatnagar S, Fatora G, Mutyala N, Grande-Allen KJ. Differential cell-matrix responses in hypoxia-stimulated aortic versus mitral valves. Journal of the Royal Society, Interface. 13. PMID 28003526 DOI: 10.1098/Rsif.2016.0449  0.506
2016 Krishnamurthy VK, Stout AJ, Sapp MC, Matuska B, Lauer ME, Grande-Allen KJ. Dysregulation of hyaluronan homeostasis during aortic valve disease. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27856308 DOI: 10.1016/J.Matbio.2016.11.003  0.485
2016 Vukicevic M, Puperi DS, Grande-Allen KJ, Little SH. Erratum to: 3D Printed Modeling of the Mitral Valve for Catheter-Based Structural Interventions. Annals of Biomedical Engineering. PMID 27411706 DOI: 10.1007/S10439-016-1690-7  0.358
2016 Blancas AA, Balaoing LR, Acosta FM, Grande-Allen KJ. Identifying Behavioral Phenotypes and Heterogeneity in Heart Valve Surface Endothelium. Cells, Tissues, Organs. 201: 268-76. PMID 27144771 DOI: 10.1159/000444446  0.454
2016 Puperi DS, O'Connell RW, Punske ZE, Wu Y, West JL, Grande-Allen KJ. Hyaluronan Hydrogels for a Biomimetic Spongiosa Layer of Tissue Engineered Heart Valve Scaffolds. Biomacromolecules. PMID 27120017 DOI: 10.1021/Acs.Biomac.6B00180  0.56
2016 Arevalos CA, Berg JM, Nguyen JM, Godfrey EL, Iriondo C, Grande-Allen KJ. Valve Interstitial Cells Act in a Pericyte Manner Promoting Angiogensis and Invasion by Valve Endothelial Cells. Annals of Biomedical Engineering. PMID 26905695 DOI: 10.1007/S10439-016-1567-9  0.499
2016 Han RI, Wheeler TM, Lumsden AB, Reardon MJ, Lawrie GM, Grande-Allen KJ, Morrisett JD, Brunner G. Morphometric analysis of calcification and fibrous layer thickness in carotid endarterectomy tissues. Computers in Biology and Medicine. 70: 210-219. PMID 26851729 DOI: 10.1016/J.Compbiomed.2016.01.019  0.316
2016 Puperi DS, Kishan A, Punske ZE, Wu Y, Cosgriff-Hernandez E, West JL, Grande-Allen KJ. Electrospun Polyurethane and Hydrogel Composite Scaffolds as Biomechanical Mimics for Aortic Valve Tissue Engineering Acs Biomaterials Science & Engineering. 2: 1546-1558. DOI: 10.1021/Acsbiomaterials.6B00309  0.563
2015 Wu Y, Puperi DS, Grande-Allen KJ, West JL. Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds. Journal of Tissue Engineering and Regenerative Medicine. PMID 26631842 DOI: 10.1002/Term.2093  0.539
2015 Pankoval D, Chen Y, Terajima M, Schliekelman MJ, Baird BN, Fahrenholtz M, Sun L, Gill BJ, Vadakkan TJ, Kim MP, Ahn YH, Roybal JD, Liu X, Parra Cuentas ER, Rodriguez J, ... ... Grande-Allen KJ, et al. Cancer-associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma. Molecular Cancer Research : McR. PMID 26631572 DOI: 10.1158/1541-7786.Mcr-15-0307  0.31
2015 Stephens EH, Nguyen TC, Blazejewski JG, Vekilov DP, Connell JP, Itoh A, Ingels NB, Miller DC, Grande-Allen KJ. Extracellular matrix remodeling in wound healing of critical size defects in the mitral valve leaflet. Heart and Vessels. PMID 26563105 DOI: 10.1007/S00380-015-0768-8  0.648
2015 Scully BB, Fan C, Grigoryan B, Jacot JG, Vick GW, Kim JJ, Fraser CD, Grande-Allen KJ, Morales DL. Remodeling of ECM patch into functional myocardium in an ovine model: A pilot study. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 26348258 DOI: 10.1002/Jbm.B.33484  0.331
2015 Fahrenholtz MM, Wen S, Grande-Allen KJ. Development of a heart valve model surface for optimization of surface modifications. Acta Biomaterialia. 26: 64-71. PMID 26296937 DOI: 10.1016/J.Actbio.2015.08.021  0.377
2015 Puperi DS, Balaoing LR, O'Connell RW, West JL, Grande-Allen KJ. 3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model. Biomaterials. 67: 354-364. PMID 26241755 DOI: 10.1016/J.Biomaterials.2015.07.039  0.502
2015 Connell PS, Azimuddin AF, Kim SE, Ramirez F, Jackson MS, Little SH, Grande-Allen KJ. Regurgitation Hemodynamics Alone Cause Mitral Valve Remodeling Characteristic of Clinical Disease States In Vitro. Annals of Biomedical Engineering. PMID 26224524 DOI: 10.1007/S10439-015-1398-0  0.58
2015 Stephens EH, Connell PS, Fahrenholtz MM, Timek TA, Daughters GT, Kuo JJ, Patton AM, Ingels NB, Miller DC, Grande-Allen KJ. Heterogeneity of Mitral Leaflet Matrix Composition and Turnover Correlates with Regional Leaflet Strain. Cardiovascular Engineering and Technology. 6: 141-150. PMID 26213589 DOI: 10.1007/S13239-015-0214-1  0.619
2015 Stephens EH, Fahrenholtz MM, Connell PS, Timek TA, Daughters GT, Kuo JJ, Patton AM, Ingels NB, Miller DC, Grande-Allen KJ. Cellular and Extracellular Matrix Basis for Heterogeneity in Mitral Annular Contraction. Cardiovascular Engineering and Technology. 6: 151-159. PMID 26195991 DOI: 10.1007/S13239-014-0209-3  0.642
2015 Balaoing LR, Post AD, Lin AY, Tseng H, Moake JL, Grande-Allen KJ. Laminin Peptide-Immobilized Hydrogels Modulate Valve Endothelial Cell Hemostatic Regulation. Plos One. 10: e0130749. PMID 26090873 DOI: 10.1371/Journal.Pone.0130749  0.681
2015 Zhang X, Xu B, Puperi DS, Wu Y, West JL, Grande-Allen KJ. Application of hydrogels in heart valve tissue engineering. Journal of Long-Term Effects of Medical Implants. 25: 105-34. PMID 25955010 DOI: 10.1615/Jlongtermeffmedimplants.2015011817  0.507
2015 Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, ... ... Grande-Allen KJ, et al. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. The Journal of Clinical Investigation. 125: 1147-62. PMID 25664850 DOI: 10.1172/Jci74725  0.326
2015 Arevalos CA, Walborn AT, Rupert AA, Berg JM, Godfrey EL, Nguyen JM, Grande-Allen KJ. Regulation of valve endothelial cell vasculogenic network architectures with ROCK and Rac inhibitors. Microvascular Research. 98: 108-18. PMID 25660064 DOI: 10.1016/J.Mvr.2015.01.008  0.441
2015 Wong FF, Ho ML, Yamagami M, Lam MT, Grande-Allen KJ, Suh J. Effective Gene Delivery to Valvular Interstitial Cells Using Adeno-Associated Virus Serotypes 2 and 3. Tissue Engineering. Part C, Methods. PMID 25603445 DOI: 10.1089/Ten.Tec.2014.0493  0.444
2015 Kheradvar A, Groves EM, Dasi LP, Alavi SH, Tranquillo R, Grande-Allen KJ, Simmons CA, Griffith B, Falahatpisheh A, Goergen CJ, Mofrad MR, Baaijens F, Little SH, Canic S. Emerging trends in heart valve engineering: Part I. Solutions for future. Annals of Biomedical Engineering. 43: 833-43. PMID 25488074 DOI: 10.1007/S10439-014-1209-Z  0.476
2015 Sapp MC, Fares HJ, Estrada AC, Grande-Allen KJ. Multilayer three-dimensional filter paper constructs for the culture and analysis of aortic valvular interstitial cells. Acta Biomaterialia. 13: 199-206. PMID 25463506 DOI: 10.1016/J.Actbio.2014.11.039  0.506
2015 Kheradvar A, Groves EM, Goergen CJ, Alavi SH, Tranquillo R, Simmons CA, Dasi LP, Grande-Allen KJ, Mofrad MR, Falahatpisheh A, Griffith B, Baaijens F, Little SH, Canic S. Emerging trends in heart valve engineering: Part II. Novel and standard technologies for aortic valve replacement. Annals of Biomedical Engineering. 43: 844-57. PMID 25449148 DOI: 10.1007/S10439-014-1191-5  0.448
2015 Zhang X, Xu B, Puperi DS, Yonezawa AL, Wu Y, Tseng H, Cuchiara ML, West JL, Grande-Allen KJ. Integrating valve-inspired design features into poly(ethylene glycol) hydrogel scaffolds for heart valve tissue engineering. Acta Biomaterialia. 14: 11-21. PMID 25433168 DOI: 10.1016/J.Actbio.2014.11.042  0.715
2015 Kheradvar A, Groves EM, Simmons CA, Griffith B, Alavi SH, Tranquillo R, Dasi LP, Falahatpisheh A, Grande-Allen KJ, Goergen CJ, Mofrad MR, Baaijens F, Canic S, Little SH. Emerging trends in heart valve engineering: Part III. Novel technologies for mitral valve repair and replacement. Annals of Biomedical Engineering. 43: 858-70. PMID 25287646 DOI: 10.1007/S10439-014-1129-Y  0.469
2015 Balaoing LR, Post AD, Lin AY, Tseng H, Moake JL, Grande-Allen KJ. Laminin peptide-immobilized hydrogels modulate valve endothelial cell hemostatic regulation Plos One. 10. DOI: 10.1371/journal.pone.0130749  0.621
2015 Stephens EH, Fahrenholtz MM, Connell PS, Timek TA, Daughters GT, Kuo JJ, Patton AM, Ingels NB, Miller DC, Grande-Allen KJ. Cellular and Extracellular Matrix Basis for Heterogeneity in Mitral Annular Contraction Cardiovascular Engineering and Technology. 6: 151-159. DOI: 10.1007/s13239-014-0209-3  0.582
2014 Wiltz DC, Han RI, Wilson RL, Kumar A, Morrisett JD, Grande-Allen KJ. Differential Aortic and Mitral Valve Interstitial Cell Mineralization and the Induction of Mineralization by Lysophosphatidylcholine In Vitro. Cardiovascular Engineering and Technology. 5: 371-383. PMID 25419248 DOI: 10.1007/S13239-014-0197-3  0.505
2014 Kamel PI, Qu X, Geiszler AM, Nagrath D, Harmancey R, Taegtmeyer H, Grande-Allen KJ. Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells. Journal of the Royal Society, Interface / the Royal Society. 11: 20140852. PMID 25320066 DOI: 10.1098/Rsif.2014.0852  0.411
2014 Tseng H, Puperi DS, Kim EJ, Ayoub S, Shah JV, Cuchiara ML, West JL, Grande-Allen KJ. Anisotropic poly(ethylene glycol)/polycaprolactone hydrogel-fiber composites for heart valve tissue engineering. Tissue Engineering. Part A. 20: 2634-45. PMID 24712446 DOI: 10.1089/ten.TEA.2013.0397  0.694
2014 Balaoing LR, Post AD, Liu H, Minn KT, Grande-Allen KJ. Age-related changes in aortic valve hemostatic protein regulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 72-80. PMID 24177329 DOI: 10.1161/Atvbaha.113.301936  0.542
2014 Tseng H, Balaoing LR, Grigoryan B, Raphael RM, Killian TC, Souza GR, Grande-Allen KJ. A three-dimensional co-culture model of the aortic valve using magnetic levitation. Acta Biomaterialia. 10: 173-82. PMID 24036238 DOI: 10.1016/J.Actbio.2013.09.003  0.721
2014 Fahrenholtz M, Liu H, Kearney D, Wadhwa L, Fraser C, Grande-Allen K. Characterization of Dermal Fibroblasts as a Cell Source for Pediatric Tissue Engineered Heart Valves Journal of Cardiovascular Development and Disease. 1: 146-162. DOI: 10.3390/Jcdd1020146  0.474
2014 Connell P, Azimuddin A, Kim E, Jackson M, Little S, Grande-Allen KJ. EXPANDING THE CHARACTERIZATION OF MITRAL VALVE DISEASE USING MODELS CREATED IN A FLOW LOOP BIOREACTOR Journal of the American College of Cardiology. 63: A1930. DOI: 10.1016/S0735-1097(14)61933-1  0.402
2014 Kreuz JM, Erskine KN, Blancas AA, Grande-Allen KJ. Age and regional dependence of collagen crimp in heart valves Conference Proceedings of the Society For Experimental Mechanics Series. 4: 15-23. DOI: 10.1007/978-3-319-00777-9_3  0.42
2014 Connell PS, Krishnamurthy VK, Grande-Allen KJ. Bioreactor and biomaterial platforms for investigation of mitral valve biomechanics and mechanobiology Molecular Biology of Valvular Heart Disease. 95-106. DOI: 10.1007/978-1-4471-6350-3_12  0.488
2013 Tseng H, Kim EJ, Connell PS, Ayoub S, Shah JV, Grande-Allen KJ. The tensile and viscoelastic properties of aortic valve leaflets treated with a hyaluronidase gradient. Cardiovascular Engineering and Technology. 4: 151-160. PMID 38223558 DOI: 10.1007/s13239-013-0122-1  0.691
2013 Kumar A, Wiltz DC, Grande-Allen KJ. Gentamicin Reduces Calcific Nodule Formation by Aortic Valve Interstitial Cells In Vitro. Cardiovascular Engineering and Technology. 4: 16-25. PMID 25414733 DOI: 10.1007/S13239-012-0114-6  0.506
2013 Tseng H, Gage JA, Raphael RM, Moore RH, Killian TC, Grande-Allen KJ, Souza GR. Assembly of a three-dimensional multitype bronchiole coculture model using magnetic levitation. Tissue Engineering. Part C, Methods. 19: 665-75. PMID 23301612 DOI: 10.1089/Ten.Tec.2012.0157  0.649
2013 Tseng H, Cuchiara ML, Durst CA, Cuchiara MP, Lin CJ, West JL, Grande-Allen KJ. Fabrication and mechanical evaluation of anatomically-inspired quasilaminate hydrogel structures with layer-specific formulations. Annals of Biomedical Engineering. 41: 398-407. PMID 23053300 DOI: 10.1007/S10439-012-0666-5  0.647
2013 Osman N, Grande-Allen KJ, Ballinger ML, Getachew R, Marasco S, O'Brien KD, Little PJ. Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 22: 146-55. PMID 22999704 DOI: 10.1016/J.Carpath.2012.07.002  0.426
2013 Kamel P, Qu P, Nagrath D, Harmancey R, Taegtmeyer H, Grande-Allen KJ. Collagen gel contraction assay for evaluation of porcine aortic valve interstitial cell glycolytic metabolism Cardiovascular Pathology. 22: e36. DOI: 10.1016/J.Carpath.2013.01.030  0.491
2013 Zhang X, Xu B, Tseng H, Cuchiara ML, West JL, Grande-Allen KJ. Tissue engineering of aortic valve leaflets using biomimetic composite poly(ethylene glycol) diacrylate hydrogels Cardiovascular Pathology. 22: e32. DOI: 10.1016/J.Carpath.2013.01.019  0.663
2013 Arevalos CA, Martinez J, Farach-Carson MC, Grande-Allen KJ. Investigating the role of perlecan in modulating pathological angiogenesis in calcific aortic valve disease Cardiovascular Pathology. 22: e29-e30. DOI: 10.1016/J.Carpath.2013.01.011  0.4
2013 Gheewala N, Schwarz KA, Grande-Allen KJ. Organ Culture of Porcine Mitral Valves as a Novel Experimental Paradigm Cardiovascular Engineering and Technology. 4: 139-150. DOI: 10.1007/S13239-013-0140-Z  0.802
2013 Tseng H, Kim EJ, Connell PS, Ayoub S, Shah JV, Grande-Allen KJ. The Tensile and Viscoelastic Properties of Aortic Valve Leaflets Treated with a Hyaluronidase Gradient Cardiovascular Engineering and Technology. 4: 151-160. DOI: 10.1007/S13239-013-0122-1  0.697
2013 Aikawa E, Grande-Allen KJ. Biology of mitral valve disease Cardiac Valvular Medicine. 173-185. DOI: 10.1007/978-1-4471-4132-7_17  0.336
2012 Stephens EH, Saltarrelli JG, Balaoing LR, Baggett LS, Nandi I, Anderson KM, Morrisett JD, Reardon MJ, Simpson MA, Weigel PH, Olmsted-Davis EA, Davis AR, Grande-Allen KJ. Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves. Pathology, Research and Practice. 208: 642-50. PMID 23017666 DOI: 10.1016/J.Prp.2012.08.001  0.634
2012 Connell PS, Han RI, Grande-Allen KJ. Differentiating the aging of the mitral valve from human and canine myxomatous degeneration. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. 14: 31-45. PMID 22364720 DOI: 10.1016/J.Jvc.2011.11.003  0.411
2012 Stephens EH, Kearney DL, Grande-Allen KJ. Insight into pathologic abnormalities in congenital semilunar valve disease based on advances in understanding normal valve microstructure and extracellular matrix. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 21: 46-58. PMID 21349746 DOI: 10.1016/J.Carpath.2011.01.002  0.661
2012 Balaoing LR, Post AD, Lin AY, Nolasco L, Turner NA, Moake JL, Grande-Allen KJ. Biomechanical Stimuli Effects on Valve Endothelial Cell Anti-thrombotic Mechanisms Qscience Proceedings. 2012: 66. DOI: 10.5339/qproc.2012.heartvalve.4.66  0.302
2012 Tseng H, Grande-Allen K. Corrigendum to “Elastic fibers in the aortic valve spongiosa: A fresh perspective on its structure and role in overall tissue function” [Acta Biomater. 7 (2011) 2101–2108] Acta Biomaterialia. 8: 924. DOI: 10.1016/J.Actbio.2011.11.003  0.665
2011 Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, Simmons CA, Masters KS, Mathieu P, O'Brien KD, Schoen FJ, Towler DA, Yoganathan AP, Otto CM. Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Circulation. 124: 1783-91. PMID 22007101 DOI: 10.1161/Circulationaha.110.006767  0.438
2011 Durst CA, Cuchiara MP, Mansfield EG, West JL, Grande-Allen KJ. Flexural characterization of cell encapsulated PEGDA hydrogels with applications for tissue engineered heart valves. Acta Biomaterialia. 7: 2467-76. PMID 21329770 DOI: 10.1016/J.Actbio.2011.02.018  0.516
2011 Tseng H, Grande-Allen KJ. Elastic fibers in the aortic valve spongiosa: a fresh perspective on its structure and role in overall tissue function. Acta Biomaterialia. 7: 2101-8. PMID 21255691 DOI: 10.1016/J.Actbio.2011.01.022  0.604
2011 Grande-Allen KJ, Liao J. The heterogeneous biomechanics and mechanobiology of the mitral valve: implications for tissue engineering. Current Cardiology Reports. 13: 113-20. PMID 21221857 DOI: 10.1007/S11886-010-0161-2  0.545
2011 Stephens EH, Saltarrelli JG, Baggett LS, Nandi I, Kuo JJ, Davis AR, Olmsted-Davis EA, Reardon MJ, Morrisett JD, Grande-Allen KJ. Differential proteoglycan and hyaluronan distribution in calcified aortic valves. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 20: 334-42. PMID 21185747 DOI: 10.1016/J.Carpath.2010.10.002  0.647
2011 Qu X, Jimenez-Vergara AC, Munoz-Pinto DJ, Ortiz D, McMahon RE, Cristancho D, Becerra-Bayona S, Guiza-Arguello V, Grande-Allen KJ, Hahn MS. Regulation of smooth muscle cell phenotype by glycosaminoglycan identity. Acta Biomaterialia. 7: 1031-9. PMID 21094702 DOI: 10.1016/J.Actbio.2010.11.020  0.346
2011 Stephens EH, Shangkuan J, Kuo JJ, Carroll JL, Kearney DL, Carberry KE, Fraser CD, Grande-Allen KJ. Extracellular matrix remodeling and cell phenotypic changes in dysplastic and hemodynamically altered semilunar human cardiac valves. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 20: e157-67. PMID 20817569 DOI: 10.1016/J.Carpath.2010.07.004  0.691
2011 Stephens EH, Durst CA, West JL, Grande-Allen KJ. Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region. Acta Biomaterialia. 7: 75-82. PMID 20624493 DOI: 10.1016/J.Actbio.2010.07.001  0.646
2011 Scully B, Erskine K, Fan C, Durst C, Kwak M, Barzilla J, Grande-Allen K, Morales D. Matrix Degradation of a Small Intestinal Submucosa Patch Seeded with Mitral Valve Interstitial Cells Facilitates Tissue Remodeling: An In Vitro Study with a Novel Bioreactor Journal of Surgical Research. 165: 171. DOI: 10.1016/J.Jss.2010.11.869  0.776
2011 Haldar S, Gheewala N, Grande-Allen KJ, Sutton MA, Bruck HA. Multi-scale Mechanical Characterization of Palmetto Wood using Digital Image Correlation to Develop a Template for Biologically-Inspired Polymer Composites Experimental Mechanics. 51: 575-589. DOI: 10.1007/S11340-010-9422-7  0.76
2010 Stephens EH, Durst CA, Swanson JC, Grande-Allen KJ, Ingels NB, Miller DC. FUNCTIONAL COUPLING OF VALVULAR INTERSTITIAL CELLS AND COLLAGEN VIA αβ INTEGRINS IN THE MITRAL LEAFLET. Cellular and Molecular Bioengineering. 3: 428-437. PMID 37829550 DOI: 10.1007/s12195-010-0139-6  0.535
2010 Stephens EH, Carroll JL, Post AD, Kuo JJ, Grande-Allen KJ. Functional characterization of fibronectin-separated valve interstitial cell subpopulations in three-dimensional culture. The Journal of Heart Valve Disease. 19: 759-65. PMID 21214101  0.63
2010 Liao J, Guo X, Grande-Allen KJ, Kasper FK, Mikos AG. Bioactive polymer/extracellular matrix scaffolds fabricated with a flow perfusion bioreactor for cartilage tissue engineering. Biomaterials. 31: 8911-20. PMID 20797784 DOI: 10.1016/J.Biomaterials.2010.07.110  0.448
2010 Barzilla JE, McKenney AS, Cowan AE, Durst CA, Grande-Allen KJ. Design and validation of a novel splashing bioreactor system for use in mitral valve organ culture. Annals of Biomedical Engineering. 38: 3280-94. PMID 20661646 DOI: 10.1007/S10439-010-0129-9  0.493
2010 Stephens EH, Post AD, Laucirica DR, Grande-Allen KJ. Perinatal changes in mitral and aortic valve structure and composition. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 13: 447-58. PMID 20536360 DOI: 10.2350/09-11-0749-Oa.1  0.647
2010 Xu S, Grande-Allen KJ. The role of cell biology and leaflet remodeling in the progression of heart valve disease. Methodist Debakey Cardiovascular Journal. 6: 2-7. PMID 20360651 DOI: 10.14797/Mdcj-6-1-2  0.526
2010 Durst CA, Grande-Allen KJ. Design and physical characterization of a synchronous multivalve aortic valve culture system. Annals of Biomedical Engineering. 38: 319-325. PMID 19953323 DOI: 10.1007/S10439-009-9846-3  0.52
2010 Stephens EH, de Jonge N, McNeill MP, Durst CA, Grande-Allen KJ. Age-related changes in material behavior of porcine mitral and aortic valves and correlation to matrix composition. Tissue Engineering. Part A. 16: 867-78. PMID 19814589 DOI: 10.1089/Ten.Tea.2009.0288  0.664
2010 Ferdous Z, Peterson SB, Tseng H, Anderson DK, Iozzo RV, Grande-Allen KJ. A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts. Journal of Biomedical Materials Research. Part A. 93: 419-28. PMID 19569212 DOI: 10.1002/Jbm.A.32545  0.751
2010 Stephens EH, Huynh TN, Cieluch JD, Grande-Allen KJ. Fibronectin-based isolation of valve interstitial cell subpopulations: relevance to valve disease. Journal of Biomedical Materials Research. Part A. 92: 340-9. PMID 19189392 DOI: 10.1002/Jbm.A.32382  0.62
2010 Gheewala N, Grande-Allen KJ. Design and Mechanical Evaluation of a Physiological Mitral Valve Organ Culture System Cardiovascular Engineering and Technology. 1: 123-131. DOI: 10.1007/S13239-010-0012-8  0.825
2010 Stephens EH, Durst CA, Swanson JC, Grande-Allen KJ, Ingels NB, Miller DC. Functional coupling of valvular interstitial cells and collagen via α2β1 integrins in the mitral leaflet Cellular and Molecular Bioengineering. 3: 428-437. DOI: 10.1007/S12195-010-0139-6  0.588
2009 Stephens EH, Timek TA, Daughters GT, Kuo JJ, Patton AM, Baggett LS, Ingels NB, Miller DC, Grande-Allen KJ. Significant changes in mitral valve leaflet matrix composition and turnover with tachycardia-induced cardiomyopathy. Circulation. 120: S112-9. PMID 19752355 DOI: 10.1161/Circulationaha.108.844159  0.66
2009 Gupta V, Tseng H, Lawrence BD, Grande-Allen KJ. Effect of cyclic mechanical strain on glycosaminoglycan and proteoglycan synthesis by heart valve cells. Acta Biomaterialia. 5: 531-40. PMID 19004676 DOI: 10.1016/J.Actbio.2008.10.009  0.659
2009 Gupta V, Barzilla JE, Mendez JS, Stephens EH, Lee EL, Collard CD, Laucirica R, Weigel PH, Grande-Allen KJ. Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 18: 191-7. PMID 18621549 DOI: 10.1016/J.Carpath.2008.05.001  0.643
2008 Stephens EH, Nguyen TC, Itoh A, Ingels NB, Miller DC, Grande-Allen KJ. The effects of mitral regurgitation alone are sufficient for leaflet remodeling. Circulation. 118: S243-9. PMID 18824762 DOI: 10.1161/Circulationaha.107.757526  0.669
2008 Ofek G, Revell CM, Hu JC, Allison DD, Grande-Allen KJ, Athanasiou KA. Matrix development in self-assembly of articular cartilage. Plos One. 3: e2795. PMID 18665220 DOI: 10.1371/Journal.Pone.0002795  0.379
2008 Stephens EH, Chu CK, Grande-Allen KJ. Valve proteoglycan content and glycosaminoglycan fine structure are unique to microstructure, mechanical load and age: Relevance to an age-specific tissue-engineered heart valve. Acta Biomaterialia. 4: 1148-60. PMID 18448399 DOI: 10.1016/J.Actbio.2008.03.014  0.665
2008 Allison DD, Wight TN, Ripp NJ, Braun KR, Grande-Allen KJ. Endogenous overexpression of hyaluronan synthases within dynamically cultured collagen gels: Implications for vascular and valvular disease. Biomaterials. 29: 2969-76. PMID 18433861 DOI: 10.1016/j.biomaterials.2008.04.005  0.394
2008 Gupta V, Werdenberg JA, Lawrence BD, Mendez JS, Stephens EH, Grande-Allen KJ. Reversible secretion of glycosaminoglycans and proteoglycans by cyclically stretched valvular cells in 3D culture. Annals of Biomedical Engineering. 36: 1092-103. PMID 18425579 DOI: 10.1007/S10439-008-9501-4  0.695
2008 Ferdous Z, Lazaro LD, Iozzo RV, Höök M, Grande-Allen KJ. Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices. Biomaterials. 29: 2740-8. PMID 18394699 DOI: 10.1016/J.Biomaterials.2008.03.018  0.694
2008 Blevins TL, Peterson SB, Lee EL, Bailey AM, Frederick JD, Huynh TN, Gupta V, Grande-Allen KJ. Mitral valvular interstitial cells demonstrate regional, adhesional, and synthetic heterogeneity. Cells, Tissues, Organs. 187: 113-22. PMID 17851228 DOI: 10.1159/000108582  0.551
2008 Durst CA, Grande-Allen KJ. Design and development of an aortic valve culture system Society For Experimental Mechanics - 11th International Congress and Exhibition On Experimental and Applied Mechanics 2008. 1: 454-459.  0.428
2008 Barzilla JE, Grande-Allen KJ. Design of splashing bioreactor maintaining mitral valve structure in vitro Society For Experimental Mechanics - 11th International Congress and Exhibition On Experimental and Applied Mechanics 2008. 1: 446-453.  0.353
2008 Gheewala N, Grande-Allen KJ. Sterile flow loop design for mitral valve organ culture Society For Experimental Mechanics - 11th International Congress and Exhibition On Experimental and Applied Mechanics 2008. 1: 439-445.  0.814
2007 Stephens EH, Grande-Allen KJ. Age-related changes in collagen synthesis and turnover in porcine heart valves. The Journal of Heart Valve Disease. 16: 672-82. PMID 18095519  0.615
2007 Ferdous Z, Wei VM, Iozzo R, Höök M, Grande-Allen KJ. Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. The Journal of Biological Chemistry. 282: 35887-98. PMID 17942398 DOI: 10.1074/Jbc.M705180200  0.694
2007 Allison DD, Vasco N, Braun KR, Wight TN, Grande-Allen KJ. The effect of endogenous overexpression of hyaluronan synthases on material, morphological, and biochemical properties of uncrosslinked collagen biomaterials. Biomaterials. 28: 5509-17. PMID 17869336 DOI: 10.1016/J.Biomaterials.2007.08.037  0.471
2007 Grande-Allen KJ, Osman N, Ballinger ML, Dadlani H, Marasco S, Little PJ. Glycosaminoglycan synthesis and structure as targets for the prevention of calcific aortic valve disease. Cardiovascular Research. 76: 19-28. PMID 17560967 DOI: 10.1016/j.cardiores.2007.05.014  0.302
2007 Ferdous Z, Grande-Allen KJ. Utility and control of proteoglycans in tissue engineering. Tissue Engineering. 13: 1893-904. PMID 17518731 DOI: 10.1089/Ten.2006.0056  0.698
2007 Gupta V, Werdenberg JA, Blevins TL, Grande-Allen KJ. Synthesis of glycosaminoglycans in differently loaded regions of collagen gels seeded with valvular interstitial cells. Tissue Engineering. 13: 41-9. PMID 17518580 DOI: 10.1089/Ten.2006.0091  0.508
2007 Stephens EH, Carroll JL, Grande-Allen KJ. The use of collagenase III for the isolation of porcine aortic valvular interstitial cells: rationale and optimization. The Journal of Heart Valve Disease. 16: 175-83. PMID 17484468  0.585
2007 Grande-Allen K. Fibrotic vs. myxomatous remodeling of mitral valves. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2004: 3737-40. PMID 17271107 DOI: 10.1109/IEMBS.2004.1404049  0.436
2007 Stephens EH, Grande-Allen KJ. Porcine valve as a model for age-specific human heart valve disease: Analysis of collagen turnover throughout development and aging Journal of the American College of Surgeons. 205: S25. DOI: 10.1016/J.Jamcollsurg.2007.06.054  0.612
2007 Peterson SB, Ferdous Z, Höök M, Grande-Allen KJ. Decorin deficient cells demonstrate increased proliferation and altered phenotypic properties Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 985-986.  0.649
2006 Blevins TL, Carroll JL, Raza AM, Grande-Allen KJ. Phenotypic characterization of isolated valvular interstitial cell subpopulations. The Journal of Heart Valve Disease. 15: 815-22. PMID 17152790  0.36
2006 Gupta V, Grande-Allen KJ. Effects of static and cyclic loading in regulating extracellular matrix synthesis by cardiovascular cells. Cardiovascular Research. 72: 375-83. PMID 17010955 DOI: 10.1016/J.Cardiores.2006.08.017  0.463
2006 Allison DD, Grande-Allen KJ. Review. Hyaluronan: a powerful tissue engineering tool. Tissue Engineering. 12: 2131-40. PMID 16968154 DOI: 10.1089/Ten.2006.12.2131  0.378
2006 Barzilla JE, Blevins TL, Grande-Allen KJ. Age-related structural changes in cardiac valves: implications for tissue-engineered repairs. The American Journal of Geriatric Cardiology. 15: 311-5. PMID 16957451  0.387
2005 Grande-Allen KJ, Barber JE, Klatka KM, Houghtaling PL, Vesely I, Moravec CS, McCarthy PM. Mitral valve stiffening in end-stage heart failure: evidence of an organic contribution to functional mitral regurgitation. The Journal of Thoracic and Cardiovascular Surgery. 130: 783-90. PMID 16153929 DOI: 10.1016/J.Jtcvs.2005.04.019  0.426
2005 Grande-Allen KJ, Borowski AG, Troughton RW, Houghtaling PL, Dipaola NR, Moravec CS, Vesely I, Griffin BP. Apparently normal mitral valves in patients with heart failure demonstrate biochemical and structural derangements: an extracellular matrix and echocardiographic study. Journal of the American College of Cardiology. 45: 54-61. PMID 15629373 DOI: 10.1016/J.Jacc.2004.06.079  0.448
2004 Allison DD, Drazba JA, Vesely I, Kader KN, Grande-Allen KJ. Cell viability mapping within long-term heart valve organ cultures. The Journal of Heart Valve Disease. 13: 290-6. PMID 15086269  0.38
2004 Grande-Allen KJ, Calabro A, Gupta V, Wight TN, Hascall VC, Vesely I. Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: association with regions of tensile and compressive loading. Glycobiology. 14: 621-33. PMID 15044391 DOI: 10.1093/Glycob/Cwh076  0.426
2004 Grande-Allen KJ. Fibrotic vs. myxomatous remodeling of mitral valves Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 26: 3737-3740.  0.436
2003 Grande-Allen KJ, Griffin BP, Ratliff NB, Cosgrove DM, Vesely I. Glycosaminoglycan profiles of myxomatous mitral leaflets and chordae parallel the severity of mechanical alterations. Journal of the American College of Cardiology. 42: 271-7. PMID 12875763 DOI: 10.1016/S0735-1097(03)00626-0  0.536
2003 Grande-Allen KJ, Mako WJ, Calabro A, Shi Y, Ratliff NB, Vesely I. Loss of chondroitin 6-sulfate and hyaluronan from failed porcine bioprosthetic valves. Journal of Biomedical Materials Research. Part A. 65: 251-9. PMID 12734820 DOI: 10.1002/Jbm.A.10475  0.378
2002 Sedransk KL, Grande-Allen KJ, Vesely I. Failure mechanics of mitral valve chordae tendineae. The Journal of Heart Valve Disease. 11: 644-50. PMID 12358400  0.346
2001 Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Mechanisms of aortic valve incompetence: finite-element modeling of Marfan syndrome. The Journal of Thoracic and Cardiovascular Surgery. 122: 946-54. PMID 11689800 DOI: 10.1067/Mtc.2001.116314  0.409
2001 Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Finite-element analysis of aortic valve-sparing: influence of graft shape and stiffness. Ieee Transactions On Bio-Medical Engineering. 48: 647-59. PMID 11396595 DOI: 10.1109/10.923783  0.319
2000 Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Re-creation of sinuses is important for sparing the aortic valve: a finite element study. The Journal of Thoracic and Cardiovascular Surgery. 119: 753-63. PMID 10733765 DOI: 10.1016/S0022-5223(00)70011-0  0.454
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