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Ian M. Slaymaker, Ph.D. - Publications

Affiliations: 
2013 Biochemistry and Molecular Biology University of Southern California, Los Angeles, CA, United States 
Area:
Biochemistry
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chu SH, Packer M, Rees H, Lam D, Yu Y, Marshall J, Cheng LI, Lam D, Olins J, Ran FA, Liquori A, Gantzer B, Decker J, Born D, Barrera L, ... ... Slaymaker IM, et al. Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation. The Crispr Journal. 4: 169-177. PMID 33876959 DOI: 10.1089/crispr.2020.0144  0.307
2020 Porto EM, Komor AC, Slaymaker IM, Yeo GW. Base editing: advances and therapeutic opportunities. Nature Reviews. Drug Discovery. PMID 33077937 DOI: 10.1038/s41573-020-0084-6  0.338
2020 Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, et al. Directed evolution of adenine base editors with increased activity and therapeutic application. Nature Biotechnology. PMID 32284586 DOI: 10.1038/S41587-020-0491-6  0.32
2019 Slaymaker IM, Mesa P, Kellner MJ, Kannan S, Brignole E, Koob J, Feliciano PR, Stella S, Abudayyeh OO, Gootenberg JS, Strecker J, Montoya G, Zhang F. High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage. Cell Reports. 26: 3741-3751.e5. PMID 30917325 DOI: 10.1016/J.Celrep.2019.02.094  0.34
2017 Tangprasertchai NS, Di Felice R, Zhang X, Slaymaker IM, Vazquez Reyes C, Jiang W, Rohs R, Qin PZ. CRISPR-Cas9 mediated DNA unwinding detected using site-directed spin labeling. Acs Chemical Biology. PMID 28437608 DOI: 10.1016/J.Bpj.2017.11.1081  0.479
2017 Smargon AA, Cox DB, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. Molecular Cell. PMID 28065598 DOI: 10.1016/J.Molcel.2016.12.023  0.325
2016 Abudayyeh OO, Gootenberg JS, Konermann S, Joung J, Slaymaker IM, Cox DB, Shmakov S, Makarova KS, Semenova E, Minakhin L, Severinov K, Regev A, Lander ES, Koonin EV, Zhang F. C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector. Science (New York, N.Y.). PMID 27256883 DOI: 10.1126/Science.Aaf5573  0.358
2016 Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O. Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA. Cell. PMID 27114038 DOI: 10.1016/j.cell.2016.04.003  0.457
2015 Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science (New York, N.Y.). PMID 26628643 DOI: 10.1126/Science.Aad5227  0.385
2015 Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. PMID 26422227 DOI: 10.1016/J.Cell.2015.09.038  0.473
2014 Fu Y, Slaymaker IM, Wang J, Wang G, Chen XS. The 1.8-Å crystal structure of the N-terminal domain of an archaeal MCM as a right-handed filament. Journal of Molecular Biology. 426: 1512-23. PMID 24378617 DOI: 10.1016/J.Jmb.2013.12.025  0.639
2013 Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Zhou ZH, Chen XS. Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. Nucleic Acids Research. 41: 3446-56. PMID 23361460 DOI: 10.1093/Nar/Gkt022  0.652
2013 Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Hong Zhou Z, Chen XS. 123 Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology Journal of Biomolecular Structure and Dynamics. 31: 78-79. DOI: 10.1080/07391102.2013.786365  0.678
2012 Slaymaker IM, Chen XS. MCM structure and mechanics: what we have learned from archaeal MCM. Sub-Cellular Biochemistry. 62: 89-111. PMID 22918582 DOI: 10.1007/978-94-007-4572-8_6  0.609
2010 Brewster AS, Slaymaker IM, Afif SA, Chen XS. Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding. Bmc Molecular Biology. 11: 62. PMID 20716382 DOI: 10.1186/1471-2199-11-62  0.628
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