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Harshad Ghodke, Ph.D. - Publications

Affiliations: 
2013 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
General Biophysics, Biochemistry
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Whinn KS, Sharma N, van Oijen AM, Ghodke H. Single-Molecule Fluorescence Imaging of DNA Replication Stalling at Sites of Nucleoprotein Complexes. Methods in Molecular Biology (Clifton, N.J.). 2694: 215-234. PMID 37824007 DOI: 10.1007/978-1-0716-3377-9_11  0.561
2023 Cherry ME, Dubiel K, Henry C, Wood EA, Revitt-Mills SA, Keck JL, Cox MM, van Oijen AM, Ghodke H, Robinson A. Spatiotemporal Dynamics of Single-stranded DNA Intermediates in . Biorxiv : the Preprint Server For Biology. PMID 37214928 DOI: 10.1101/2023.05.08.539320  0.475
2023 Whinn KS, Xu ZQ, Jergic S, Sharma N, Spenkelink LM, Dixon NE, van Oijen AM, Ghodke H. Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase. Nucleic Acids Research. PMID 36938885 DOI: 10.1093/nar/gkad186  0.528
2022 Shaw AE, Kairamkonda S, Ghodke H, Schauer GD. Biochemical and single-molecule techniques to study accessory helicase resolution of R-loop proteins at stalled replication forks. Methods in Enzymology. 673: 191-225. PMID 35965008 DOI: 10.1016/bs.mie.2022.03.012  0.304
2021 Whinn KS, van Oijen AM, Ghodke H. Single-molecule studies of helicases and translocases in prokaryotic genome-maintenance pathways. Dna Repair. 108: 103229. PMID 34601381 DOI: 10.1016/j.dnarep.2021.103229  0.365
2020 Henrikus SS, Henry C, McGrath AE, Jergic S, McDonald JP, Hellmich Y, Bruckbauer ST, Ritger ML, Cherry ME, Wood EA, Pham PT, Goodman MF, Woodgate R, Cox MM, van Oijen AM, ... Ghodke H, et al. Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair. Nucleic Acids Research. PMID 32687193 DOI: 10.1093/Nar/Gkaa597  0.549
2020 Ghodke H, Ho HN, van Oijen AM. Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair. Nature Communications. 11: 1477. PMID 32198385 DOI: 10.1038/S41467-020-15179-Y  0.497
2020 Ho HN, van Oijen AM, Ghodke H. Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells. Nature Communications. 11: 1478. PMID 32198374 DOI: 10.1038/S41467-020-15182-3  0.525
2019 Whinn KS, Kaur G, Lewis JS, Schauer GD, Mueller SH, Jergic S, Maynard H, Gan ZY, Naganbabu M, Bruchez MP, O'Donnell ME, Dixon NE, van Oijen AM, Ghodke H. Nuclease dead Cas9 is a programmable roadblock for DNA replication. Scientific Reports. 9: 13292. PMID 31527759 DOI: 10.1038/S41598-019-49837-Z  0.545
2019 Ho HN, Zalami D, Köhler J, van Oijen AM, Ghodke H. Identification of Multiple Kinetic Populations of DNA-Binding Proteins in Live Cells. Biophysical Journal. PMID 31383358 DOI: 10.1016/J.Bpj.2019.07.015  0.392
2019 Ghodke H, Paudel BP, Lewis JS, Jergic S, Gopal K, Romero ZJ, Wood EA, Woodgate R, Cox MM, van Oijen AM. Spatial and temporal organization of RecA in the DNA-damage response. Elife. 8. PMID 30717823 DOI: 10.7554/Elife.42761  0.586
2019 Henrikus SS, Henry C, Ghodke H, Wood EA, Mbele N, Saxena R, Basu U, van Oijen AM, Cox MM, Robinson A. RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli. Nucleic Acids Research. PMID 30657965 DOI: 10.1093/Nar/Gkz003  0.592
2019 Ghodke H, Paudel BP, Lewis JS, Jergic S, Gopal K, Romero ZJ, Wood EA, Woodgate R, Cox MM, Oijen AMv. Author response: Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response Elife. DOI: 10.7554/Elife.42761.026  0.429
2019 Whinn KS, Oijen AMv, Ghodke H. Spy-ing on Cas9: Single-molecule tools reveal the enzymology of Cas9 Current Opinion in Biomedical Engineering. 12: 25-33. DOI: 10.1016/J.Cobme.2019.08.013  0.431
2018 Monachino E, Ghodke H, Spinks RR, Hoatson BS, Jergic S, Xu ZQ, Dixon NE, van Oijen AM. Design of DNA rolling-circle templates with controlled fork topology to study mechanisms of DNA replication. Analytical Biochemistry. PMID 30016625 DOI: 10.1016/J.Ab.2018.07.008  0.555
2018 Ren W, Wen S, Tawfik SA, Su QP, Lin G, Ju LA, Ford MJ, Ghodke H, van Oijen AM, Jin D. Anisotropic functionalization of upconversion nanoparticles. Chemical Science. 9: 4352-4358. PMID 29780568 DOI: 10.1039/C8Sc01023D  0.324
2018 Ho HN, van Oijen AM, Ghodke H. The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage. Nature Communications. 9: 1570. PMID 29679003 DOI: 10.1038/S41467-018-03790-Z  0.421
2017 Ghodke H, Lewis JS, van Oijen AM. Resolving the Gordian Knot: Srs2 Strips Intermediates Formed during Homologous Recombination. Trends in Biochemical Sciences. PMID 29290471 DOI: 10.1016/J.Tibs.2017.12.004  0.449
2017 Ghodke H, Ho H, van Oijen AM. Single-molecule live-cell imaging of bacterial DNA repair and damage tolerance. Biochemical Society Transactions. PMID 29196610 DOI: 10.1042/Bst20170055  0.563
2016 Ghodke H, Caldas VE, Punter CM, van Oijen AM, Robinson A. Single-Molecule Specific Mislocalization of Red Fluorescent Proteins in Live Escherichia coli. Biophysical Journal. PMID 27338860 DOI: 10.1016/J.Bpj.2016.05.047  0.325
2015 Robinson A, McDonald JP, Caldas VE, Patel M, Wood EA, Punter CM, Ghodke H, Cox MM, Woodgate R, Goodman MF, van Oijen AM. Regulation of Mutagenic DNA Polymerase V Activation in Space and Time. Plos Genetics. 11: e1005482. PMID 26317348 DOI: 10.1371/Journal.Pgen.1005482  0.489
2015 Caldas VE, Punter CM, Ghodke H, Robinson A, van Oijen AM. iSBatch: a batch-processing platform for data analysis and exploration of live-cell single-molecule microscopy images and other hierarchical datasets. Molecular Biosystems. 11: 2699-708. PMID 26198886 DOI: 10.1039/C5Mb00321K  0.347
2014 Ghodke H, Wang H, Hsieh CL, Woldemeskel S, Watkins SC, Rapić-Otrin V, Van Houten B. Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates. Proceedings of the National Academy of Sciences of the United States of America. 111: E1862-71. PMID 24760829 DOI: 10.1073/Pnas.1323856111  0.578
2013 Paredes E, Zhang X, Ghodke H, Yadavalli VK, Das SR. Backbone-branched DNA building blocks for facile angular control in nanostructures. Acs Nano. 7: 3953-61. PMID 23600590 DOI: 10.1021/Nn305787M  0.549
2013 Hughes CD, Wang H, Ghodke H, Simons M, Towheed A, Peng Y, Van Houten B, Kad NM. Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic Acids Research. 41: 4901-12. PMID 23511970 DOI: 10.1093/Nar/Gkt177  0.582
2013 Godin S, Wier A, Kabbinavar F, Bratton-Palmer DS, Ghodke H, Van Houten B, VanDemark AP, Bernstein KA. The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Research. 41: 4525-34. PMID 23460207 DOI: 10.1093/Nar/Gkt138  0.527
2013 Ghodke H, Wang H, Hsieh CL, Gibson G, Watkins S, Rapic-Otrin V, Levine AS, Houten BV. WT UV-DDB Performs a 3D Search on DNA whereas the XP-E Mutant (K244E DDB2) Mutant Slides Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.462  0.574
2012 Yeh JI, Levine AS, Du S, Chinte U, Ghodke H, Wang H, Shi H, Hsieh CL, Conway JF, Van Houten B, Rapić-Otrin V. Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proceedings of the National Academy of Sciences of the United States of America. 109: E2737-46. PMID 22822215 DOI: 10.1073/Pnas.1110067109  0.567
2011 Wang H, Nora GJ, Ghodke H, Opresko PL. Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding. The Journal of Biological Chemistry. 286: 7479-89. PMID 21183684 DOI: 10.1074/Jbc.M110.205641  0.536
2010 Ghodke H, Wang H, Cotner-Gohara E, Kim I, Ellenberger T, Houten BV. Direct Visualization Of Joining of DNA Fragments By LigIIIβ Using Atomic Force Microscopy Biophysical Journal. 98: 67. DOI: 10.1016/J.Bpj.2009.12.383  0.58
2007 Ghodke HB, Krishnan R, Vignesh K, Kumar GV, Narayana C, Krishnan Y. The I-tetraplex building block: rational design and controlled fabrication of robust 1D DNA scaffolds through non-Watson-Crick interactions. Angewandte Chemie (International Ed. in English). 46: 2646-9. PMID 17330917 DOI: 10.1002/Anie.200604461  0.303
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