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Andre Richters - Publications

Affiliations: 
2015-2017 Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Richters A, Doyle SK, Freeman DB, Lee C, Leifer BS, Jagannathan S, Kabinger F, Koren JV, Struntz NB, Urgiles J, Stagg RA, Curtin BH, Chatterjee D, Mathea S, Mikochik PJ, et al. Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors. Cell Chemical Biology. PMID 33086052 DOI: 10.1016/j.chembiol.2020.10.001  0.4
2018 Leifer BS, Doyle SK, Richters A, Evans HL, Koehler AN. An Array-Based Ligand Discovery Platform for Proteins With Short Half-Lives. Methods in Enzymology. 610: 191-218. PMID 30390799 DOI: 10.1016/Bs.Mie.2018.09.019  0.65
2017 Richters A. Targeting protein arginine methyltransferase 5 in disease. Future Medicinal Chemistry. PMID 29076773 DOI: 10.4155/Fmc-2017-0089  0.44
2017 Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, et al. Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Reports. 20: 2833-2845. PMID 28930680 DOI: 10.1016/J.Celrep.2017.08.082  0.469
2017 Plenker D, Riedel M, Brägelmann J, Dammert MA, Chauhan R, Knowles PP, Lorenz C, Keul M, Bührmann M, Pagel O, Tischler V, Scheel AH, Schütte D, Song Y, Stark J, ... ... Richters A, et al. Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Science Translational Medicine. 9. PMID 28615362 DOI: 10.1126/Scitranslmed.Aah6144  0.445
2017 Waldmann H, Robke L, Laraia L, Carnero Corrales MA, Konstantinidis G, Muroi M, Richters A, Winzker M, Engbring T, Tomassi S, Watanabe N, Osada H, Rauh D, Wu Y, Engel J. Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34. Angewandte Chemie (International Ed. in English). PMID 28544137 DOI: 10.1002/Anie.201703738  0.414
2017 Richters A, Koehler AN. Epigenetic Modulation using Small Molecules - Targeting Histone Acetyltransferases in Disease. Current Medicinal Chemistry. PMID 28240169 DOI: 10.2174/0929867324666170223153115  0.663
2016 Radi M, Schneider R, Fallacara AL, Botta L, Crespan E, Tintori C, Maga G, Kissova M, Calgani A, Richters A, Musumeci F, Rauh D, Schenone S. A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant. Bioorganic & Medicinal Chemistry Letters. PMID 27374241 DOI: 10.1016/J.Bmcl.2016.06.051  0.418
2015 Basu D, Richters A, Rauh D. Corrigendum to "Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR" [Bioorg. Med. Chem. 23, 2015, 2767-2780]. Bioorganic & Medicinal Chemistry. 23: 5075. PMID 32689707 DOI: 10.1016/J.Bmc.2015.06.001  0.361
2015 Engel J, Richters A, Getlik M, Tomassi S, Keul M, Termathe M, Lategahn J, Becker C, Mayer-Wrangowski S, Grütter C, Uhlenbrock N, Krüll J, Schaumann N, Eppmann S, Kibies P, et al. Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. Journal of Medicinal Chemistry. 58: 6844-63. PMID 26275028 DOI: 10.1021/Acs.Jmedchem.5B01082  0.462
2015 Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozretić L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, et al. A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer. Cell. 162: 146-59. PMID 26140595 DOI: 10.1016/J.Cell.2015.05.053  0.433
2015 Weisner J, Gontla R, van der Westhuizen L, Oeck S, Ketzer J, Janning P, Richters A, Mühlenberg T, Fang Z, Taher A, Jendrossek V, Pelly SC, Bauer S, van Otterlo WA, Rauh D. Covalent-Allosteric Kinase Inhibitors. Angewandte Chemie (International Ed. in English). 54: 10313-6. PMID 26110718 DOI: 10.1002/Anie.201502142  0.383
2015 Basu D, Richters A, Rauh D. Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR. Bioorganic & Medicinal Chemistry. 23: 2767-80. PMID 25975640 DOI: 10.1016/J.Bmc.2015.04.038  0.416
2015 Schröder P, Förster T, Kleine S, Becker C, Richters A, Ziegler S, Rauh D, Kumar K, Waldmann H. Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. Angewandte Chemie (International Ed. in English). PMID 25908259 DOI: 10.1002/Anie.201501515  0.399
2015 Richters A, Basu D, Engel J, Ercanoglu MS, Balke-Want H, Tesch R, Thomas RK, Rauh D. Identification and further development of potent TBK1 inhibitors. Acs Chemical Biology. 10: 289-98. PMID 25540906 DOI: 10.1021/Cb500908D  0.451
2015 Tintori C, Fallacara AL, Radi M, Zamperini C, Dreassi E, Crespan E, Maga G, Schenone S, Musumeci F, Brullo C, Richters A, Gasparrini F, Angelucci A, Festuccia C, Delle Monache S, et al. Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma. Journal of Medicinal Chemistry. 58: 347-61. PMID 25469771 DOI: 10.1021/Jm5013159  0.416
2015 Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozretić L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, et al. Erratum: A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer (Cell (2015) 162 (146-159)) Cell. 162. DOI: 10.1016/J.Cell.2015.08.017  0.397
2014 Richters A, Nguyen HD, Phan T, Simard JR, Grütter C, Engel J, Rauh D. Identification of type II and III DDR2 inhibitors. Journal of Medicinal Chemistry. 57: 4252-62. PMID 24754677 DOI: 10.1021/Jm500167Q  0.4
2014 Malchers F, Dietlein F, Schöttle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, ... ... Richters A, et al. Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer. Cancer Discovery. 4: 246-57. PMID 24302556 DOI: 10.1158/2159-8290.Cd-13-0323  0.443
2013 Baur B, Storch K, Martz KE, Goettert MI, Richters A, Rauh D, Laufer SA. Metabolically stable dibenzo[ b, e ]oxepin-11(6 H)-ones as highly selective p38 MAP kinase inhibitors: Optimizing anti-cytokine activity in human whole blood Journal of Medicinal Chemistry. 56: 8561-8578. PMID 24131218 DOI: 10.1021/Jm401276H  0.333
2013 Richters A, Ketzer J, Getlik M, Grütter C, Schneider R, Heuckmann JM, Heynck S, Sos ML, Gupta A, Unger A, Schultz-Fademrecht C, Thomas RK, Bauer S, Rauh D. Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design. Journal of Medicinal Chemistry. 56: 5757-72. PMID 23773153 DOI: 10.1021/Jm4004076  0.421
2013 Urich R, Wishart G, Kiczun M, Richters A, Tidten-Luksch N, Rauh D, Sherborne B, Wyatt PG, Brenk R. De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments. Acs Chemical Biology. 8: 1044-52. PMID 23534475 DOI: 10.1021/Cb300729Y  0.424
2012 Sos ML, Dietlein F, Peifer M, Schöttle J, Balke-Want H, Müller C, Koker M, Richters A, Heynck S, Malchers F, Heuckmann JM, Seidel D, Eyers PA, Ullrich RT, Antonchick AP, et al. A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 17034-9. PMID 23035247 DOI: 10.1073/Pnas.1207310109  0.448
2012 Grütter C, Simard JR, Mayer-Wrangowski SC, Schreier PH, Pérez-Martín J, Richters A, Getlik M, Gutbrod O, Braun CA, Beck ME, Rauh D. Targeting GSK3 from Ustilago maydis: type-II kinase inhibitors as potential antifungals. Acs Chemical Biology. 7: 1257-67. PMID 22545924 DOI: 10.1021/Cb300128B  0.387
2012 Koch A, Rode HB, Richters A, Rauh D, Hauf S. A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase. Acs Chemical Biology. 7: 723-31. PMID 22264160 DOI: 10.1021/Cb200465C  0.415
2010 Rabiller M, Getlik M, Klüter S, Richters A, Tückmantel S, Simard JR, Rauh D. Proteus in the world of proteins: conformational changes in protein kinases. Archiv Der Pharmazie. 343: 193-206. PMID 20336692 DOI: 10.1002/Ardp.201000028  0.353
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