Thomas Braulke - Publications

Affiliations: 
UKE Hamburg 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sachs W, Sachs M, Krüger E, Zielinski S, Kretz O, Huber TB, Baranowsky A, Westermann LM, Voltolini Velho R, Ludwig NF, Yorgan TA, Di Lorenzo G, Kollmann K, Braulke T, Schwartz IV, et al. Distinct Modes of Balancing Glomerular Cell Proteostasis in Mucolipidosis Type II and III Prevent Proteinuria. Journal of the American Society of Nephrology : Jasn. PMID 32641396 DOI: 10.1681/ASN.2019090960  0.32
2018 Pohl S, Angermann A, Jeschke A, Hendrickx G, Yorgan TA, Makrypidi-Fraune G, Steigert A, Kuehn SC, Rolvien T, Schweizer M, Koehne T, Neven M, Winter O, Velho RV, Albers J, ... ... Braulke T, et al. The lysosomal protein arylsulfatase B is a key enzyme involved in skeletal turnover. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30075049 DOI: 10.1002/jbmr.3563  0.32
2018 Di Lorenzo G, Voltolini Velho R, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S. Lysosomal proteome and secretome analysis identifies missorted enzymes and their non-degraded substrates in mucolipidosis III mouse cells. Molecular & Cellular Proteomics : McP. PMID 29773673 DOI: 10.1074/mcp.RA118.000720  0.32
2017 Ludwig NF, Velho RV, Sperb-Ludwig F, Acosta AX, Ribeiro EM, Kim C, Gandelman Horovitz DD, Boy R, Rodovalho-Doriqui MJ, Lourenço CM, Santos ES, Braulke T, Pohl S, Schwartz IVD. GNPTAB missense mutations cause loss of GlcNAc-1-phosphotransferase activity in mucolipidosis type II through distinct mechanisms. The International Journal of Biochemistry & Cell Biology. PMID 28918368 DOI: 10.1016/j.biocel.2017.09.006  0.32
2017 Velho RV, De Pace R, Klünder S, Di Lorenzo G, Schweizer M, Braulke T, Pohl S. Site-1 protease and lysosomal homeostasis. Biochimica Et Biophysica Acta. 1864: 2162-2168. PMID 28693924 DOI: 10.1016/j.bbamcr.2017.06.023  0.32
2016 Velho RV, De Pace R, Tidow H, Braulke T, Pohl S. Identification of the interaction domains between α- and γ-subunits of GlcNAc-1-phosphotransferase. Febs Letters. 590: 4287-4295. PMID 27736005 DOI: 10.1002/1873-3468.12456  0.32
2015 Blackler RJ, Evans DW, Smith DF, Cummings RD, Brooks CL, Braulke T, Liu X, Evans SV, Müller-Loennies S. Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide specific binding pocket that distinguishes N-glycan phosphorylation in a branch specific manner. Glycobiology. PMID 26503547 DOI: 10.1093/glycob/cwv093  0.32
2015 Kuehn SC, Koehne T, Cornils K, Markmann S, Riedel C, Pestka JM, Schweizer M, Baldauf C, Yorgan TA, Krause M, Keller J, Neven M, Breyer S, Stuecker R, Muschol N, ... ... Braulke T, et al. Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I. Human Molecular Genetics. PMID 26427607 DOI: 10.1093/hmg/ddv407  0.32
2015 De Pace R, Velho RV, Encarnação M, Marschner K, Braulke T, Pohl S. Subunit interactions of the disease-related hexameric GlcNAc-1-phosphotransferase complex. Human Molecular Genetics. 24: 6826-35. PMID 26385638 DOI: 10.1093/hmg/ddv387  0.32
2015 Varga RE, Khundadze M, Damme M, Nietzsche S, Hoffmann B, Stauber T, Koch N, Hennings JC, Franzka P, Huebner AK, Kessels MM, Biskup C, Jentsch TJ, Qualmann B, Braulke T, et al. In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11. Plos Genetics. 11: e1005454. PMID 26284655 DOI: 10.1371/journal.pgen.1005454  0.32
2015 Klünder S, Heeren J, Markmann S, Santer R, Braulke T, Pohl S. Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control. Journal of Lipid Research. 56: 1625-32. PMID 26108224 DOI: 10.1194/jlr.M060756  0.32
2015 Velho RV, De Pace R, Klünder S, Sperb-Ludwig F, Lourenço CM, Schwartz IV, Braulke T, Pohl S. Analyses of disease-related GNPTAB mutations define a novel GlcNAc-1-phosphotransferase interaction domain and an alternative site-1 protease cleavage site. Human Molecular Genetics. 24: 3497-505. PMID 25788519 DOI: 10.1093/hmg/ddv100  0.32
2014 Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, ... ... Braulke T, et al. Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metabolism. 19: 605-17. PMID 24703693 DOI: 10.1016/j.cmet.2014.03.014  0.32
2014 De Pace R, Coutinho MF, Koch-Nolte F, Haag F, Prata MJ, Alves S, Braulke T, Pohl S. Mucolipidosis II-related mutations inhibit the exit from the endoplasmic reticulum and proteolytic cleavage of GlcNAc-1-phosphotransferase precursor protein (GNPTAB). Human Mutation. 35: 368-76. PMID 24375680 DOI: 10.1002/humu.22502  0.32
2014 Madhavarao CN, Agarabi CD, Wong L, Müller-Loennies S, Braulke T, Khan M, Anderson H, Johnson GR. Evaluation of butyrate-induced production of a mannose-6-phosphorylated therapeutic enzyme using parallel bioreactors. Biotechnology and Applied Biochemistry. 61: 184-92. PMID 24033810 DOI: 10.1002/bab.1151  0.32
2013 Khundadze M, Kollmann K, Koch N, Biskup C, Nietzsche S, Zimmer G, Hennings JC, Huebner AK, Symmank J, Jahic A, Ilina EI, Karle K, Schöls L, Kessels M, Braulke T, et al. A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system. Plos Genetics. 9: e1003988. PMID 24367272 DOI: 10.1371/journal.pgen.1003988  0.32
2012 van Rahden VA, Brand K, Najm J, Heeren J, Pfeffer SR, Braulke T, Kutsche K. The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module. Human Molecular Genetics. 21: 5019-38. PMID 22907655 DOI: 10.1093/hmg/dds343  0.32
2012 Thelen M, Damme M, Da??e M, Schweizer M, Hagel C, Wong AM, Cooper JD, Braulke T, Galliciotti G. Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis. Plos One. 7: e35493. PMID 22536393 DOI: 10.1371/journal.pone.0035493  0.32
2011 Puig B, Altmeppen HC, Thurm D, Geissen M, Conrad C, Braulke T, Glatzel M. N-glycans and glycosylphosphatidylinositol-anchor act on polarized sorting of mouse PrP(C) in Madin-Darby canine kidney cells. Plos One. 6: e24624. PMID 21931781 DOI: 10.1371/journal.pone.0024624  0.32
2011 Lebrun AH, Moll-Khosrawi P, Pohl S, Makrypidi G, Storch S, Kilian D, Streichert T, Otto B, Mole SE, Ullrich K, Cotman S, Kohlschütter A, Braulke T, Schulz A. Analysis of potential biomarkers and modifier genes affecting the clinical course of CLN3 disease. Molecular Medicine (Cambridge, Mass.). 17: 1253-61. PMID 21863212 DOI: 10.2119/molmed.2010.00241  0.32
2011 Marschner K, Kollmann K, Schweizer M, Braulke T, Pohl S. A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolism Science. 333: 87-90. PMID 21719679 DOI: 10.1126/science.1205677  0.32
2011 Muschol N, Pohl S, Meyer A, Gal A, Ullrich K, Braulke T. Residual activity and proteasomal degradation of p.Ser298Pro sulfamidase identified in patients with a mild clinical phenotype of Sanfilippo A syndrome American Journal of Medical Genetics, Part A. 155: 1634-1639. PMID 21671382 DOI: 10.1002/ajmg.a.34053  0.32
2011 Encarnação M, Kollmann K, Trusch M, Braulke T, Pohl S. Post-translational modifications of the γ-subunit affect intracellular trafficking and complex assembly of GlcNAc-1-phosphotransferase Journal of Biological Chemistry. 286: 5311-5318. PMID 21173149 DOI: 10.1074/jbc.M110.202382  0.32
2010 Pohl S, Tiede S, Marschner K, Encarnação M, Castrichini M, Kollmann K, Muschol N, Ullrich K, Müller-Loennies S, Braulke T. Proteolytic processing of the γ-subunit is associated with the failure to form GlcNAc-1-phosphotransferase complexes and mannose 6-phosphate residues on lysosomal enzymes in human macrophages Journal of Biological Chemistry. 285: 23936-23944. PMID 20489197 DOI: 10.1074/jbc.M110.129684  0.32
2010 Pohl S, Encarnacão M, Castrichini M, Müller-Loennies S, Muschol N, Braulke T. Loss of N-acetylglucosamine-1-phosphotransferase gamma subunit due to intronic mutation in GNPTG causes mucolipidosis type III gamma: Implications for molecular and cellular diagnostics. American Journal of Medical Genetics. Part A. 152: 124-32. PMID 20034096 DOI: 10.1002/ajmg.a.33170  0.32
2010 Kollmann K, Pohl S, Marschner K, Encarnação M, Sakwa I, Tiede S, Poorthuis BJ, Lübke T, Müller-Loennies S, Storch S, Braulke T. Mannose phosphorylation in health and disease. European Journal of Cell Biology. 89: 117-23. PMID 19945768 DOI: 10.1016/j.ejcb.2009.10.008  0.32
2009 Pohl S, Tiede S, Castrichini M, Cantz M, Gieselmann V, Braulke T. Compensatory expression of human N-acetylglucosaminyl-1-phosphotransferase subunits in mucolipidosis type III gamma. Biochimica Et Biophysica Acta. 1792: 221-5. PMID 19708128 DOI: 10.1016/j.bbadis.2009.01.009  0.32
2009 Pohl S, Marschner K, Storch S, Braulke T. Glycosylation- and phosphorylation-dependent intracellular transport of lysosomal hydrolases. Biological Chemistry. 390: 521-7. PMID 19426136 DOI: 10.1515/BC.2009.076  0.32
2007 Pohl S, Mitchison HM, Kohlschütter A, van Diggelen O, Braulke T, Storch S. Increased expression of lysosomal acid phosphatase in CLN3-defective cells and mouse brain tissue. Journal of Neurochemistry. 103: 2177-88. PMID 17868323 DOI: 10.1111/j.1471-4159.2007.04920.x  0.32
2007 Storch S, Pohl S, Quitsch A, Falley K, Braulke T. C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes. Traffic (Copenhagen, Denmark). 8: 431-44. PMID 17286803 DOI: 10.1111/j.1600-0854.2007.00537.x  0.32
2004 Storch S, Pohl S, Braulke T. A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting. The Journal of Biological Chemistry. 279: 53625-34. PMID 15469932 DOI: 10.1074/jbc.M410930200  0.32
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