| Year |
Citation |
Score |
| 2024 |
Chen Z, Yu J, Wang H, Xu P, Fan L, Sun F, Huang S, Zhang P, Huang H, Gu S, Zhang B, Zhou Y, Wan X, Pei G, Xu HE, et al. Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell. PMID 38552625 DOI: 10.1016/j.cell.2024.02.034 |
0.403 |
|
| 2023 |
Liu H, Zheng Y, Wang Y, Wang Y, He X, Xu P, Huang S, Yuan Q, Zhang X, Wang L, Jiang K, Chen H, Li Z, Liu W, Wang S, et al. Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature. PMID 37935377 DOI: 10.1038/s41586-023-06775-1 |
0.5 |
|
| 2023 |
Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, et al. Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nature Communications. 14: 5004. PMID 37591889 DOI: 10.1038/s41467-023-40705-z |
0.454 |
|
| 2023 |
Xu P, Huang S, Krumm BE, Zhuang Y, Mao C, Zhang Y, Wang Y, Huang XP, Liu YF, He X, Li H, Yin W, Jiang Y, Zhang Y, Roth BL, et al. Structural genomics of the human dopamine receptor system. Cell Research. PMID 37221270 DOI: 10.1038/s41422-023-00808-0 |
0.518 |
|
| 2023 |
You C, Zhang Y, Xu Y, Xu P, Li Z, Li H, Huang S, Chen Z, Li J, Xu HE, Jiang Y. Structural basis for motilin and erythromycin recognition by motilin receptor. Science Advances. 9: eade9020. PMID 36921049 DOI: 10.1126/sciadv.ade9020 |
0.53 |
|
| 2023 |
Duan J, Xu P, Zhang H, Luan X, Yang J, He X, Mao C, Shen DD, Ji Y, Cheng X, Jiang H, Jiang Y, Zhang S, Zhang Y, Xu HE. Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature Communications. 14: 519. PMID 36720854 DOI: 10.1038/s41467-023-36170-3 |
0.456 |
|
| 2022 |
Xu P, Huang S, Guo S, Yun Y, Cheng X, He X, Cai P, Lan Y, Zhou H, Jiang H, Jiang Y, Xie X, Xu HE. Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119. Nature Structural & Molecular Biology. PMID 35970999 DOI: 10.1038/s41594-022-00816-5 |
0.524 |
|
| 2022 |
Duan J, Xu P, Luan X, Ji Y, He X, Song N, Yuan Q, Jin Y, Cheng X, Jiang H, Zheng J, Zhang S, Jiang Y, Xu HE. Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature. PMID 35940204 DOI: 10.1038/s41586-022-05173-3 |
0.424 |
|
| 2022 |
Huang S, Xu P, Shen DD, Simon IA, Mao C, Tan Y, Zhang H, Harpsøe K, Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE, et al. GPCRs steer G and G selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Molecular Cell. PMID 35714614 DOI: 10.1016/j.molcel.2022.05.031 |
0.426 |
|
| 2022 |
Tan Y, Xu P, Huang S, Yang G, Zhou F, He X, Ma H, Xu HE, Jiang Y. Structural insights into the ligand binding and G coupling of serotonin receptor 5-HT. Cell Discovery. 8: 50. PMID 35610220 DOI: 10.1038/s41421-022-00412-3 |
0.422 |
|
| 2022 |
Shao Z, Tan Y, Shen Q, Hou L, Yao B, Qin J, Xu P, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, et al. Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discovery. 8: 44. PMID 35570218 DOI: 10.1038/s41421-022-00403-4 |
0.534 |
|
| 2022 |
You C, Zhang Y, Xu P, Huang S, Yin W, Eric Xu H, Jiang Y. Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nature Communications. 13: 2045. PMID 35440625 DOI: 10.1038/s41467-022-29683-w |
0.463 |
|
| 2022 |
Duan J, Shen DD, Zhao T, Guo S, He X, Yin W, Xu P, Ji Y, Chen LN, Liu J, Zhang H, Liu Q, Shi Y, Cheng X, Jiang H, et al. Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors. Nature Communications. 13: 1364. PMID 35292680 DOI: 10.1038/s41467-022-29072-3 |
0.471 |
|
| 2021 |
Duan J, Xu P, Cheng X, Mao C, Croll T, He X, Shi J, Luan X, Yin W, You E, Liu Q, Zhang S, Jiang H, Zhang Y, Jiang Y, et al. Structures of full-length glycoprotein hormone receptor signalling complexes. Nature. PMID 34552239 DOI: 10.1038/s41586-021-03924-2 |
0.496 |
|
| 2021 |
Wang Y, Guo S, Zhuang Y, Yun Y, Xu P, He X, Guo J, Yin W, Xu HE, Xie X, Jiang Y. Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor. Nature Communications. 12: 5064. PMID 34417468 DOI: 10.1038/s41467-021-25364-2 |
0.511 |
|
| 2021 |
Huang S, Xu P, Tan Y, You C, Zhang Y, Jiang Y, Xu HE. Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT-G protein complex. Cell Research. PMID 34239069 DOI: 10.1038/s41422-021-00527-4 |
0.431 |
|
| 2021 |
Cong Z, Chen LN, Ma H, Zhou Q, Zou X, Ye C, Dai A, Liu Q, Huang W, Sun X, Wang X, Xu P, Zhao L, Xia T, Zhong W, et al. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nature Communications. 12: 3763. PMID 34145245 DOI: 10.1038/s41467-021-24058-z |
0.402 |
|
| 2021 |
Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, et al. Structural insights into the lipid and ligand regulation of serotonin receptors. Nature. PMID 33762731 DOI: 10.1038/s41586-021-03376-8 |
0.349 |
|
| 2021 |
Zhuang Y, Xu P, Mao C, Wang L, Krumm B, Zhou XE, Huang S, Liu H, Cheng X, Huang XP, Shen DD, Xu T, Liu YF, Wang Y, Guo J, et al. Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell. PMID 33571431 DOI: 10.1016/j.cell.2021.01.027 |
0.486 |
|
| 2021 |
Xu P, Huang S, Mao C, Krumm BE, Zhou XE, Tan Y, Huang XP, Liu Y, Shen DD, Jiang Y, Yu X, Jiang H, Melcher K, Roth BL, Cheng X, et al. Structures of the human dopamine D3 receptor-G complexes. Molecular Cell. PMID 33548201 DOI: 10.1016/j.molcel.2021.01.003 |
0.546 |
|
| 2020 |
Duan J, Shen DD, Zhou XE, Bi P, Liu QF, Tan YX, Zhuang YW, Zhang HB, Xu PY, Huang SJ, Ma SS, He XH, Melcher K, Zhang Y, Xu HE, et al. Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy. Nature Communications. 11: 4121. PMID 32807782 DOI: 10.1038/S41467-020-17933-8 |
0.558 |
|
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