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Marikki Laiho - Publications

Affiliations: 
Department of Radiation Oncology and Molecular Radiation Sciences Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ford BL, Wei T, Liu H, Scull CE, Najmi SM, Pitts S, Fan W, Schneider DA, Laiho M. Expression of RNA polymerase I catalytic core is influenced by RPA12. Plos One. 18: e0285660. PMID 37167337 DOI: 10.1371/journal.pone.0285660  0.604
2022 Pitts S, Laiho M. Regulation of RNA Polymerase I Stability and Function. Cancers. 14. PMID 36497261 DOI: 10.3390/cancers14235776  0.631
2022 Jacobs RQ, Fuller KB, Cooper SL, Carter ZI, Laiho M, Lucius AL, Schneider DA. RNA Polymerase I Is Uniquely Vulnerable to the Small-Molecule Inhibitor BMH-21. Cancers. 14. PMID 36428638 DOI: 10.3390/cancers14225544  0.681
2022 Pitts S, Liu H, Ibrahim A, Garg A, Felgueira CM, Begum A, Fan W, Teh S, Low JY, Ford B, Schneider DA, Hay R, Laiho M. Identification of an E3 ligase that targets the catalytic subunit of RNA polymerase I upon transcription stress. The Journal of Biological Chemistry. 102690. PMID 36372232 DOI: 10.1016/j.jbc.2022.102690  0.485
2022 Dorado TE, de León P, Begum A, Liu H, Chen D, Rajeshkumar NV, Rey-Rodriguez R, Hoareau-Aveilla C, Alcouffe C, Laiho M, Barrow JC. Discovery and Evaluation of Novel Angular Fused Pyridoquinazolinonecarboxamides as RNA Polymerase I Inhibitors. Acs Medicinal Chemistry Letters. 13: 608-614. PMID 35450366 DOI: 10.1021/acsmedchemlett.1c00660  0.667
2021 Jacobs RQ, Huffines AK, Laiho M, Schneider DA. The small-molecule BMH-21 directly inhibits transcription elongation and DNA occupancy of RNA polymerase I in vivo and in vitro. The Journal of Biological Chemistry. 298: 101450. PMID 34838819 DOI: 10.1016/j.jbc.2021.101450  0.628
2020 Low JY, Brennen WN, Meeker AK, Ikonen E, Simons BW, Laiho M. Stromal CAVIN1 controls prostate cancer microenvironment and metastasis by modulating lipid distribution and inflammatory signaling. Molecular Cancer Research : McR. PMID 32493699 DOI: 10.1158/1541-7786.Mcr-20-0364  0.356
2019 Low JY, Sirajuddin P, Moubarek M, Agarwal S, Rege A, Guner G, Liu H, Yang Z, De Marzo AM, Bieberich C, Laiho M. Effective targeting of RNA polymerase I in treatment-resistant prostate cancer. The Prostate. PMID 31524299 DOI: 10.1002/Pros.23909  0.471
2019 Shah AA, Laiho M, Rosen A, Casciola-Rosen L. Scleroderma patients with antibodies against the large subunits of both RNA polymerases-I and -III are protected against cancer. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30888702 DOI: 10.1002/Art.40893  0.487
2018 Wei T, Najmi SM, Liu H, Peltonen K, Kucerova A, Schneider DA, Laiho M. Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint. Cell Reports. 23: 404-414. PMID 29642000 DOI: 10.1016/j.celrep.2018.03.066  0.54
2017 Guner G, Sirajuddin P, Zheng Q, Bai B, Brodie A, Liu H, Af Hallstrom T, Kulac I, Laiho M, De Marzo AM. Novel Assay to Detect RNA Polymerase I Activity in vivo. Molecular Cancer Research : McR. PMID 28119429 DOI: 10.1158/1541-7786.Mcr-16-0246  0.425
2016 Bai B, Laiho M. Deep Sequencing Analysis of Nucleolar Small RNAs: Bioinformatics. Methods in Molecular Biology (Clifton, N.J.). 1455: 243-8. PMID 27576724 DOI: 10.1007/978-1-4939-3792-9_19  0.494
2016 Bai B, Laiho M. Deep Sequencing Analysis of Nucleolar Small RNAs: RNA Isolation and Library Preparation. Methods in Molecular Biology (Clifton, N.J.). 1455: 231-41. PMID 27576723 DOI: 10.1007/978-1-4939-3792-9_18  0.537
2015 Bai B, Laiho M. Sequential recovery of macromolecular components of the nucleolus. Methods in Molecular Biology (Clifton, N.J.). 1228: 43-51. PMID 25311121 DOI: 10.1007/978-1-4939-1680-1_5  0.412
2014 Peltonen K, Colis L, Liu H, Jäämaa S, Zhang Z, Af Hällström T, Moore HM, Sirajuddin P, Laiho M. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Molecular Cancer Therapeutics. 13: 2537-46. PMID 25277384 DOI: 10.1158/1535-7163.Mct-14-0256  0.563
2014 Bai B, Yegnasubramanian S, Wheelan SJ, Laiho M. RNA-Seq of the nucleolus reveals abundant SNORD44-derived small RNAs. Plos One. 9: e107519. PMID 25203660 DOI: 10.1371/Journal.Pone.0107519  0.517
2014 Bai B, Liu H, Laiho M. Small RNA expression and deep sequencing analyses of the nucleolus reveal the presence of nucleolus-associated microRNAs. Febs Open Bio. 4: 441-9. PMID 24918059 DOI: 10.1016/j.fob.2014.04.010  0.347
2014 Colis L, Ernst G, Sanders S, Liu H, Sirajuddin P, Peltonen K, DePasquale M, Barrow JC, Laiho M. Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors. Journal of Medicinal Chemistry. 57: 4950-61. PMID 24847734 DOI: 10.1021/Jm5004842  0.62
2014 Peltonen K, Colis L, Liu H, Trivedi R, Moubarek MS, Moore HM, Bai B, Rudek MA, Bieberich CJ, Laiho M. A targeting modality for destruction of RNA polymerase I that possesses anticancer activity. Cancer Cell. 25: 77-90. PMID 24434211 DOI: 10.1016/J.Ccr.2013.12.009  0.472
2013 Bai B, Moore HM, Laiho M. CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis. Nucleus (Austin, Tex.). 4: 315-25. PMID 23782956 DOI: 10.4161/nucl.25342  0.454
2013 Moore HM, Bai B, Matilainen O, Colis L, Peltonen K, Laiho M. Proteasome activity influences UV-mediated subnuclear localization changes of NPM. Plos One. 8: e59096. PMID 23554979 DOI: 10.1371/journal.pone.0059096  0.356
2012 Bai B, Laiho M. Efficient sequential recovery of nucleolar macromolecular components Proteomics. 12: 3044-3048. PMID 22890538 DOI: 10.1002/pmic.201200071  0.309
2012 Zhu L, Jäämaa S, Af Hällström TM, Laiho M, Sankila A, Nordling S, Stenman UH, Koistinen H. PSA forms complexes with α1-antichymotrypsin in prostate. The Prostate. 73: 219-26. PMID 22806587 DOI: 10.1002/pros.22560  0.347
2011 Ni X, Zhang Y, Ribas J, Chowdhury WH, Castanares M, Zhang Z, Laiho M, DeWeese TL, Lupold SE. Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts. The Journal of Clinical Investigation. 121: 2383-90. PMID 21555850 DOI: 10.1172/Jci45109  0.444
2008 Hällström TM, Laiho M. Genetic changes and DNA damage responses in the prostate. The Prostate. 68: 902-18. PMID 18324675 DOI: 10.1002/pros.20746  0.359
2007 Kiviharju-af Hällström TM, Jäämaa S, Mönkkönen M, Peltonen K, Andersson LC, Medema RH, Peehl DM, Laiho M. Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement. Proceedings of the National Academy of Sciences of the United States of America. 104: 7211-6. PMID 17431037 DOI: 10.1073/pnas.0609299104  0.303
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