Keith A. Wafford
Affiliations: | Eli Lilly, Indianapolis, IN, United States |
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| Kato AS, Burris KD, Gardinier KM, et al. (2016) Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine |
| Jensen ML, Wafford KA, Brown AR, et al. (2013) A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors. British Journal of Pharmacology. 168: 1118-32 |
| Gilmour G, Broad LM, Wafford KA, et al. (2013) In vitro characterisation of the novel positive allosteric modulators of the mGluâ‚… receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. Neuropharmacology. 64: 224-39 |
| Mirza NR, Atack J, Wafford K. (2012) GABA(A) Receptor Subtypes: Novel Targets for Novel Medicines. Advances in Pharmacological Sciences. 2012: 529861 |
| Mirza NR, Atack J, Wafford K. (2012) GABA A receptor subtypes: Novel targets for novel medicines Advances in Pharmacological Sciences. 2012 |
| Atack JR, Hallett DJ, Tye S, et al. (2011) Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist. Journal of Psychopharmacology (Oxford, England). 25: 329-44 |
| Atack JR, Wafford KA, Street LJ, et al. (2011) MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans. Journal of Psychopharmacology (Oxford, England). 25: 314-28 |
| Mortensen M, Ebert B, Wafford K, et al. (2010) Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors. The Journal of Physiology. 588: 1251-68 |
| Wafford KA, van Niel MB, Ma QP, et al. (2009) Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus. Neuropharmacology. 56: 182-9 |
| Herd MB, Haythornthwaite AR, Rosahl TW, et al. (2008) The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. The Journal of Physiology. 586: 989-1004 |